Central New York Regional Emergency Medical Services Council, Inc. Jefferson Tower – Suite LL1 50 Presidential Plaza Syracuse, New York 13202 www.cnyems.org Phone: (315) 701-5707 (800) 295-2195 Fax: (315) 701-5709 Zofran Fact Sheet Brand name: Zofran ODT, Zofran Generic name: Ondansetron hydrochloride Classification: Antiemetic Indications: For the prevention and treatment of nausea and vomiting caused by radiation therapy or chemotherapy for cancer, and, in some cases, to prevent these problems following surgery. Contraindications: Known hypersensitivity to medication or similar medications such as Anzemet or Kytril. Decreased liver function, intestinal obstruction, and cardiac arrhythmias. Side Effects: Constipation, diarrhea, dizziness, fatigue, headache, hypotension Dose: Ondansetron (Zofran) 0.1 mg/kg up to 4 mg IV. Repeat once after 2 minutes as needed. Additional dose per medical control. CNYEMS Minimum Required Equipment: 2ml single dose vial (2mg/ml) ALS Ambulances: 2 vials ambulance and 1 vial portable kit ALS FR: 3 vials portable kit