COMBINED LIST OF DRUGS THAT PROLONG QT AND/OR CAUSE TORSADES DE POINTES (TDP)
Crediblemeds.org is your trusted partner providing reliable information on medicines. This
is a composite list of drugs that CredibleMeds has concluded either 1) have a risk of TdP,
2) prolong QT and therefore have a possible risk of TdP or 3) have a risk of TdP under
certain conditions such as overdose, drugdrug interactions or when administered to
certain high-risk individuals (e.g. congenital long QT syndrome).
Generic Name
Brand Name
Generic Name
Brand Name
Generic Name
Brand Name
Alfuzosin
Uroxatral®
Desipramine
Pertofrane® and others
Ibutilide
Corvert®
Amantadine
Symmetrel® and others
Dexmedetomidine
Precedex® and others
Iloperidone
Fanapt® and others
Amiodarone
Cordarone® and others
Dihydroartemisinin+piperaquine
Eurartesim®
Imipramine (melipramine)
Tofranil®
Amisulpride
Solian® and others
Diphenhydramine
Benadryl® and others
Indapamide
Lozol® and others
Amitriptyline
Elavil® (Discontinued 6/13)
and others
Disopyramide
Norpace®
Isradipine
Dynacirc®
Dofetilide
Tikosyn®
Itraconazole
Sporanox® and others
Amoxapine
Asendin® and others
Dolasetron
Anzemet®
Ivabradine (Not on US mkt)
Procoralan® and others
Anagrelide
Agrylin® and others
Domperidone (Not on US mkt)
Motilium® and others
Ketoconazole
Nizoral® and others
Apomorphine
Apokyn® and others
Doxepin
Sinequan® and others
Lapatinib
Tykerb® and others
Aripiprazole
Abilify® and others
Dronedarone
Multaq®
Levofloxacin
Levaquin® and others
Arsenic trioxide
Trisenox®
Droperidol
Inapsine® and others
Levomethadyl (Off US mkt)
Orlaam®
Astemizole (Off US mkt)
Hismanal®
Eribulin
Halaven®
Lithium
Eskalith® and others
Atazanavir
Reyataz®
Erythromycin
E.E.S.® and others
Mesoridazine (Off US mkt)
Serentil®
Azithromycin
Zithromax® and others
Escitalopram
Cipralex® and others
Methadone
Dolophine® and others
Bedaquiline
Sirturo®
Famotidine
Pepcid® and others
Metronidazole
Flagyl® and many others
Bepridil (Off US mkt)
Vascor®
Felbamate
Felbatol®
Mifepristone
Korlym® and others
Bortezomib
Velcade® and others
Fingolimod
Gilenya®
Mirabegron
Myrbetriq®
Bosutinib
Bosulif®
Flecainide
Tambocor® and others
Mirtazapine
Remeron
Chloral hydrate
Aquachloral® and others
Fluconazole
Diflucan® and others
Moexipril/HCTZ
Uniretic® and others
Chloroquine
Aralen®
Fluoxetine
Prozac® and others
Moxifloxacin
Avelox® and others
Chlorpromazine
Thorazine® and others
Foscarnet
Foscavir®
Nelfinavir
Viracept®
Ciprofloxacin
Cipro® and others
Fosphenytoin
Cerebyx® and others
Nicardipine
Cardene®
Cisapride (Off US mkt)
Propulsid®
Furosemide (Frusemide)
Lasix® and others
Nilotinib
Tasigna®
Citalopram
Celexa® and others
Galantamine
Reminyl® and others
Norfloxacin
Noroxin® and others
Clarithromycin
Biaxin® and others
Gatifloxacin (Off US mkt)
Tequin®
Nortriptyline
Pamelor® and others
Clomipramine
Anafranil®
Gemifloxacin
Factive®
Ofloxacin
Floxin®
Clozapine
Clozaril® and others
Granisetron
Kytril® and others
Olanzapine
Zyprexa® and others
Cocaine
Cocaine
Halofantrine
Halfan®
Ondansetron
Zofran® and others
Crizotinib
Xalkori®
Haloperidol
Haldol® (US & UK) and others
Oxytocin
Pitocin® and others
Dabrafenib
Tafinlar®
Hydrochlorothiazide
Apo-Hydro® and others
Paliperidone
Invega® and others
Dasatinib
Sprycel®
If list is printed, check website for updates: www.crediblemeds.org •Please see Disclaimer and list continued
COMBINED LIST OF DRUGS THAT PROLONG QT AND/OR CAUSE TORSADES DE POINTES (TDP)
Crediblemeds.org is your trusted partner providing reliable information on medicines. This
is a composite list of drugs that CredibleMeds has concluded either 1) have a risk of TdP,
2) prolong QT and therefore have a possible risk of TdP or 3) have a risk of TdP under
certain conditions such as overdose, drugdrug interactions or when administered to
certain high-risk individuals (e.g. congenital long QT syndrome).
Generic Name
Brand Name
Generic Name
Brand Name
Paroxetine
Paxil® and others
Sorafenib
Nexavar®
Pasireotide
Signifor®
Sotalol
Betapace® and others
Pazopanib
Votrient®
Sparfloxacin (Off US mkt)
Zagam®
Pentamidine
Pentam®
Dogmatil® and others
Perflutren lipid
microspheres
Sulpiride (Not on US
Mkt.)
Definity®
Sunitinib
Sutent®
Pimozide
Orap®
Tacrolimus
Prograf® and others
Pipamperone (Not on
US Mkt)
Dipiperon (E.U) and
others
Tamoxifen
Nolvadex®(discontinued
6/13) and others
Posaconazole
Noxafil® and others
Telaprevir
Incivek® and others
Probucol (Off US mkt)
Lorelco®
Telavancin
Vibativ®
Procainamide (Oral off
US mkt)
Pronestyl® and others
Telithromycin
Ketek®
Terfenadine (Off US mkt)
Seldane®
Promethazine
Phenergan®
Protriptyline
Vivactil®
Tetrabenazine (Orphan
drug in US)
Nitoman® and others
Quetiapine
Seroquel®
Thioridazine
Mellaril® and others
Quinidine
Quinaglute® and others
Tizanidine
Zanaflex® and others
Quinine sulfate
Qualaquin®
Tolterodine
Detrol® and others
Ranolazine
Ranexa® and others
Toremifene
Fareston®
Rilpivirine
Edurant® and others
Trazodone
Risperidone
Risperdal®
Desyrel® (discontinued
6/13) and others
Ritonavir
Norvir®
Trimethoprim-Sulfa
Septra® and others
Trimipramine
Surmontil® and others
Vandetanib
Caprelsa®
Vardenafil
Levitra®
Vemurafenib
Zelboraf®
Venlafaxine
Effexor® and others
Voriconazole
VFend®
Vorinostat
Zolinza®
Ziprasidone
Geodon® and others
Roxithromycin (Not on
US Mkt)
Rulide® and others
Saquinavir
Invirase®(combo)
Sertindole (Not on US
mkt)
Serdolect® and others
Sertraline
Zoloft® and others
Sevoflurane
Ulane® and others
Solifenacin
VESIcare®
Generated: June 2, 2014.
Note: Medicines on this list are reviewed on an ongoing
basis to assure that the available evidence supports their
continued placement on this list. The list changes regularly
and we recommend checkingthe website at
crediblemeds.org for the most up-todate information.
There may be many additional brand names that are not
listed on this form.
Disclaimer and Waiver: The information presented is
intended solely for the purpose of providing general
information about health-related matters. It is not intended
for any other purpose, including but not limited to medical
advice and/or treatment, nor is it intended to substitute for
the users relationships with their own health care
providers. To that extent, by use of this website and the
information it contains, the user affirms the understanding
of the purpose and releases AZCERT, Inc. from any
claims arising out of his/her use of the website and its lists.
The absence of drugs from these lists should not be
considered an indication that they are free of risk of QT
prolongation or TdP. Many medicines have not been
tested for this risk in patients, especially those with
congenital long QT syndrome.
List last revised: May 31, 2014