References To Introduction Slide 3 1. What is Longevity Management Medicine? http://www.baucominstitute.com/management/. 2. Longevity and Age Management / http://www.worldhealth.net/list/news/. 3. Richard F Walker. Challenges facing age-management/longevity medicine / Clin Interv Aging. 2007; 2(2): 175– 177. Slide 4 4. Life extension / http://en.wikipedia.org/wiki/Life_extension Slide 5 5. Trumpeter Lionel Ferbos, 102: Jazz keeps him going. By STACEY PLAISANCE — Jul. 19 12:55 PM EDT http://bigstory.ap.org/article/trumpeter-lionel-ferbos-102-jazz-keeps-him-going 6. Ida Herbert, 96, holds Guinness World Record for oldest yoga teacher http://www.thestar.com/news/canada/2012/09/10/ida_herbert_96_holds_guinness_world_record_for_olde st_yoga_teacher.html 7. 'Turbaned tornado', world's oldest marathon runner, retires. By Katie Hunt, for CNN - February 25, 2013 -Updated 0813 GMT (1613 HKT) http://edition.cnn.com/2013/02/25/world/marathon-man-retires Slide 6 8. Steroid. From Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Steroid 9. Steroid hormone biosynthesis - Reference pathway. http://www.genome.jp/keggbin/show_pathway?map00140 Slide 7 10. Berson SA, Yalow RS. Peptide hormones in plasma / Harvey Lect 1966-1967; 62:107-163. 11. Farfel Z, Bourne HR, Iiri T. The expanding spectrum of G protein diseases / N Engl J Med 1999; 340:1012-1020. 12. Larsen PR, Kronenberg HM, Melmed S, Polonsky KS (eds). Williams Textbook of 13. Endocrinology, 10th ed. Philadelphia: WB Saunders, 2003. 14. Losel RM, Falkenstein E, Feuring M, et al. Nongenomic steroid action: Controversies, questions, and answers / Physiol Rev 2003; 83:965-1016. 15. Missale C, Nash SR, Robinson SW, et al. Dopamine receptors: From structure to function / Physiol Rev 1998; 78:189-225. 16. Scatchard G. The attraction of proteins for small molecules and ions / Ann N Y Acad Sci 1949; 51:660-672. Slide 8 17. Berson SA, Yalow RS: Assay of insulin in human subjects by immunological methods / Nature 1959; 184:19481949. 18. Elgin RC, Busby WL, Clemmons DR: An insulin-like growth factor inding protein enhances the biological response to IGF-1 / Proc Natl Acad Sci U S A 1987; 84:3254-3258. 19. Upton GV, Amatruda TT Jr: Evidence for the presence of tumor peptides with corticotropin-releasing-factor– like activity in the ectopic ACTH syndrome / N Engl J Med 1971; 285:419-424. 20. Yu D, Yu S, Schuster V, et al: Identification of two novel deletion mutations within the Gs alpha gene (GNAS1) in Albright hereditary osteodystrophy / J Clin Endocrinol Metab. 1999; 84:3254-3259. Slide 9 21. Hormones in Harmony. http://genesisgold.com/hormones-in-harmony_329.html. ©LONGEVITY IS LIFE, LLC 2013 UNAUTHORIZED DUPLICATION IS ILLEGAL FORM 107 Slide 10 22. Receptor (biochemistry) From Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Receptor_(biochemistry) 23. Mechanism of Action: Hormones with Cell Surface Receptors. http: //www.vivo.colostate.edu/hbooks/pathphys/endocrine/moaction/surface.html 24. Pietras RJ, Nemere I, Szego CM. Steroid hormone receptors in target cell membranes / Endocrine. 2001 Apr;14(3):417-27. Slide 11 25. Leung PC, Cheng CK, Zhu XM. Multi-factorial role of GnRH-I and GnRH-II in the human ovary / Mol. Cell. Endocrinol. 2004, 202 (1–2): 145–153. 26. Guillemin R. Hypothalamic hormones a.k.a. hypothalamic releasing factors / J Endocrinol 2005;184:11-28. Slide 12 27. Endocrine gland. From Wikipedia, the free encyclopedia http://en.wikipedia.org/wiki/Endocrine_gland 28. Glands of the Human Endocrine System http://www.ivy-rose.co.uk/HumanBody/Endocrine/Endocrine_Glands.php Slide 13 29. Changes in Hormone Levels. http://www.menopause.org/for-women/sexual-health-menopauseonline/changes-at-midlife/changes-in-hormone-levels 30. LifeKick Time Machine. Testosterone and Growth Hormone booster for men http://www.lifekick.us/hormonesthatdecline.htm Slide 14 31. Estrogen. From Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Estrogen 32. Testosterone. From Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Testosterone 33. Dehydroepiandrosterone. From Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Dehydroepiandrosterone Slide 15 34. Bioidentical Hormone Replacement Therapy - BHRT - Healthy Living and Longevity. http://www.hllmc.com/bioidentical-hormone-replacement-therapy.html 35. S Panico, R Galasso, E Celentano, A V Ciardullo, L Frova, R Capocaccia, M Trevisan, and F Berrino. Large-scale hormone replacement therapy and life expectancy: results from an international comparison among European and North American populations / Am J Public Health. 2000 September; 90(9): 1397–1402. Slide 16 36. 9 Differences between the Male and Female Brain. http://www.brainfitnessforlife.com/9-differencesbetween-the-male-and-female-brain/ 37. How Male and Female Brains Differ. Researchers reveal sex differences in the brain's form and function. http://www.webmd.com/balance/features/how-male-female-brains-differ ©LONGEVITY IS LIFE, LLC 2013 UNAUTHORIZED DUPLICATION IS ILLEGAL FORM 107 Slide 17 38. Pitcher Aging Curves: Starters and Relievers. Bill Petti - May 2, 2012. http://www.fangraphs.com/blogs/pitcher-aging-curves-starters-and-relievers/ Slide 18 39. Live Longer Live Better. C. Chauchard. Limited and exclusive VIP version Slide 19 40. Bioidentical Hormones London. http://bio-identical-london.webs.com/hormonedecline.htm 41. Rainer Fischer. Bioidentical Hormones For Symptoms of Menopause in Women And Declined Sex Hormones in Men. http://www.aznd.com/ Slide 20 42. Medroxyprogesterone acetate. From Wikipedia, the free encyclopedia http://en.wikipedia.org/wiki/Medroxyprogesterone_acetate 43. Medroxyprogesterone Acetate. http://www.drugs.com/monograph/medroxyprogesterone-acetate.html Slide 21 44. Topical medication. From Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Topical_medication 45. Zaghi, D; Maibach. Survey of Safety and efficacy information in drug inserts for topical prescription medications / American Journal of Clinical Dermatology. 2007; 8 (1): 43–46. 46. Guidance for Industry. Bioavailability and Bioequivalence Studies for Orally Administered Drug Products — General Considerations. U.S. Department of Health and Human Services. Food and Drug Administration. Center for Drug Evaluation and Research (CDER). March 2003. BP Revision 1. Slide 22 47. Hormonal Balancing: Menopause, Andropause and Other Pauses. Dr. M. Nunley. http://marshanunleymd.com/bio-identical-hormones-balancing/ 48. Avoiding Problems with Progesterone. Article by Dr. Michael Borkin, N.M.D. Alternative Medicine Magazine September 1999. http://www.healthyhormones.com/news/news02.htm Slide 23 49. Tsai EC, Matsumoto AM, Fujimoto WY, Boyko EJ. Association of bioavailable, free, and total testosterone with insulin resistance: influence of sex hormone-binding globulin and body fat / Diabetes Care. 2004;27(4):861-8. 50. Alicia Stanton, Vera Tweed. Hormone Harmony: How to Balance Insulin, Cortisol, Thyroid, Estrogen, Progesterone and Testosterone To Live Your Best Life. http://www.amazon.com/Hormone-HarmonyCortisol-Progesterone-Testosterone/dp/0967873398 Slide 24 51. Hormone Restoration for Health and Quality of Life. Dr. H. Lindner. http://hormonerestoration.com/ 52. Optimal Hormone Levels Key to 'Longevity' Posted on April 9, 2013. http://www.king5.com/new-daynorthwest/Optimal-Hormone-Levels-Key-to-Longevity-202145561.html ©LONGEVITY IS LIFE, LLC 2013 UNAUTHORIZED DUPLICATION IS ILLEGAL FORM 107