Maths for Healthcare Professionals Mathematics Skills Guide All the information that you require to enable you to pass the mathematics tests within your course is contained within. Contents Fractions Page 2 Decimals Page 11 Ratio Page 17 Percentages Page 21 BMI Page 29 Averages Page 30 Unit Conversion Page 31 Dosage Calculations Page 36 Web: www.hull.ac.uk/skills Email: skills@hull.ac.uk Fractions A fraction is the ratio of two integers (whole numbers) Example , The number at the top is called the numerator, the number at the bottom is called the denominator. has a numerator 2 and denominator 5. It is spoken ‘two fifths’. has a numerator 3 and denominator 7. It is spoken ‘three sevenths’. Equivalent Fractions Here is shaded Here is shaded Here is shaded In all three diagrams the shaded regions represent the same quantity so that = = The fractions are said to be equivalent. Fractions are equivalent if you can convert one into the other by multiplying (or dividing) the numerator and the denominator by the same number. Examples is equivalent to since → is equivalent to 2 → since is equivalent to → since Equivalent fractions are needed when we come to addition and subtraction of fractions. The preferred form for a fraction is the simplest i.e. when numerator and denominator have no common factors so that we cannot divide any further. For example can be made simpler by dividing numerator and denominator by 7 to get and we cannot make any simpler. This simplification is called cancelling. Cancelling fractions makes them easier to work with particularly when multiplying and dividing them. The four operations we need to look at are , +, - and ÷ and in that order:Multiplication We can get a simple rule for this operation as follows: ↑ The shaded area in the diagram Represents 3 x 4 = 12 4 ↓ ← → 3 and if we use the same idea but the sides of the diagram now represent 1 unit we can illustrate The shaded area in the diagram represents x = ↑ (= after cancelling) ↓ ← → 3 The rule is:- multiply numerators, multiply denominators Examples i) ii) iii) Algebraically = (= after cancelling) = Addition + Type I If two (or more) fractions have the same denominator, then we just add the numerators Examples It is easy to see this is the correct method by looking at the following diagram ← →+← 2/8 → The shaded region is Similarly Type II If the fractions have different denominators then it is not possible to use the above method. We do, however, have a technique for changing fractions to equivalent fractions and we use this to convert two fractions with different denominators into two fractions with the same denominator and then just use the Type I method. Examples i) If we multiply the numerator and denominator of 4 by 4 i.e. → and if we multiply the numerator and denominator of by 5 i.e. → we have produced two equivalent fractions whose denominators are the same. We can now simply add:ii) = + Multiply numerator and denominator of by 4 and multiply numerator and denominator of by 3 to produce two equivalent fractions:- → , and + = Choosing what we multiply by is not difficult. It is (usually) the denominator of the other fraction. Example + Multiply numerator and denominator of by 5 (the denominator of ) to get Multiply numerator and denominator of by 7 (the denominator of to get = Then Do not forget to cancel your fractions, if possible, to produce the simplest form of your answer. Example = and So, , which equals , which equals (simplest form) Subtraction This is done in exactly the same way except instead of adding we subtract! Example (same denominators, so Type I subtraction) 5 - (different denominators so produce equivalent fractions) → and → so Algebraically, so + - = = and - = = This looks a little awkward, but if we look at the answer we can, very quickly, produce it as follows + 2nd term A C + B D 3rd term 1st term 3 1 1 4 + 3 7 = + 3 4 12 3 4 4 12 12 5 2 + 1 5 2 = 10 4 + 5 = 9 10 10 4 Division ÷ To find a method for this operation we proceed as follows: 6 (just rewriting the sum) = (multiply numerator and denominator by the same number to produce an equivalent fraction) x 12 = 2 x 124 31 3 x 123 41 = = (simplifying) Before working this out (using the method from multiplying fractions) look at the expression we have obtained. has become i.e. the first fraction has remained the same, the divide sign ÷ has become times x, and the second fraction has turned upside down. This happens in general and gives us a simple method for dividing fractions. Examples i) ii) = iii) Algebraically Summarising i) = 7 ii) iii) It is best NOT to remember these as formulas but as methods. Mixed Numbers If we have a, so called, mixed number to deal with, i.e. a fraction and a whole number Examples 2 , 4 , it is best to convert the whole number to a top heavy fraction or improper fraction, perform the operation using the above rules, and then convert back to a mixed number if necessary. Examples i) 2 3 2 → So 2 ii) 3 3 So 3 and 3 → (cancelling) and 2 → = To convert a mixed number to a fraction we multiply the whole number by the denominator of the fraction and then add on the numerator. Schematically A Again do NOT remember this as a formula but as a method. 8 Fractions Exercise 1. For each group of fractions, state which fractions are equivalent: a) 1,1,2,3 2 4 4 4 6 4 b) 83 , 72 , 21 , 15 9 2 12 c) 54 , 10 , 3 , 15 2. Cancel the following fractions down to their simplest form: a) 5 25 36 108 b) 20 c) 64 3. For each of the following pairs of fractions, state which one is the larger: a) 3 7 , 4 8 b) 5,6 8 7 c) 12 , 3 15 5 4. Convert the following mixed fractions into improper fractions: a) 5 78 5 c) 2 16 b) 6 81 5. Convert the following improper fractions into mixed fractions: a) 18 5 c) 19 3 b) 26 7 6. Work out the following (simplify your answer if possible): a) 4× 15 3 c) 6× 12 b) 5× 89 Note: Any whole number can be written as a fraction with denominator 1, ie. 3 = , 7 = , and we just use the usual rules so 3 x = x = 7. Work out the following (simplify your answer if possible): a) 1 4 × 15 b) 3 8 × 12 c) 54 × 23 8. Work out the following divisions (simplify your answer if possible): a) 8 9 ÷ 23 b) 3 7 ÷ 1 2 c) 4 5 ÷ 15 9. Work out the following divisions (simplify your answer if possible): a) 2 3 ÷4 b) 1 2 ÷8 c) 9 5 8 ÷6 Fractions Exercise - Answers 1. a) 1 , 2 2 4 6 b) 72 , 21 c) 4 , 12 6. a) 54 b) 40 9 c) 32 2. a) 1 5 b) 13 5 c) 16 7. 1 a) 20 3 b) 16 8 c) 15 3. a) 7 8 b) 8. a) 43 b) 76 c) 4 4. a) 47 8 b) 49 8 37 c) 16 9. a) 16 1 b) 16 5 c) 48 5. a) 3 3 5 b) 3 75 c) 6 13 6 7 5 15 c) 12 15 10 Decimals 1.5, 2.7, 1.333, 12.6 are all decimals. The decimal point (.) is used to distinguish the parts of the number. Numbers to the left of the decimal point are the normal counting numbers. Numbers to the right of the decimal point are parts of numbers. Example 123.456. Here we have 123 and a bit. The bit is 0.456. Place Value The value of a number is dependent upon its position. This is called its place value. Thousands Tens Units • Tenths Hundredths Thousandths 1 1 • 0 2 • 5 5 7 • 9 6 0 • 0 1 0 4 The table above shows how place value works for decimals. 1.01 means one unit and one hundredth. 2.5 means two units and 5 tenths. 57.9 means five tens, seven units and 9 tenths 160.004 means one hundred, 6 tens, and 4 thousandths Decimal-Speak It is usual to say the numbers after the decimal point as individual numbers. For example 4.93 would be said as ‘four point nine three’ not ‘four point ninety three’ Notice that where a number does not have a value for a column, a nought is used. This preserves the value of the numbers following. In this way 0.2 is different from 0.02 in the same way that 20 is different from 2. As with numbers in front of the decimal point, noughts not contained within a number are not usually written i.e. 5.1 is really 5.1000000000000000000000000… but we can just assume that the following noughts are there. 11 Multiplying and dividing by 10/100/1000 etc. When we multiply a number by ten its digits remain the same but the decimal point moves one place to the right. Examples 12.4 x 10 = 124 231.47 x 10 = 2314.7 14 x 10 = 140 0.03 x 10 = 0.3 When we multiply a number by one hundred its digits remain the same but the decimal point moves two places to the right. Examples 1.24 x 100 = 124 433.62 x 100 = 43362 8.4124 x 100 = 841.24 When we multiply a number by one thousand its digits remain the same but the decimal point moves three places to the right. Examples 2.316 x 1000 = 2316 81.42 x 1000 = 81420 0.0031 x 1000 = 3.1 When multiplying we just move the decimal point as many places as there are noughts to the right. Division is the inverse process to multiplication so that when dividing by 10/100/1000 we simply reverse the above process. Examples 12 ÷ 10 = 1.2 21 ÷ 100 = 0.21 274 ÷ 1000 = 0.274 ie. we move the decimal one, two or three places but this time to the left. 12 Multiplying Decimals We get a method for this by noting that 32.4 = and 2.42 = using the ideas from the previous section. So 32.4 x 2.42 = x We perform the usual long multiplication 324 242 64800 And now divide by 10 and 100, ie. move the decimal point three places,1 place from 32.4 and 2 places from 2.42 to get 78.408 12960 648 78408 This is why the method works. We can abbreviate it to: Just perform a long multiplication, ignoring the decimal point Now put the decimal point back in the answer – it will have just as many decimal places as the two original numbers combined. Example 214 231 42800 6420 214 49434 Example 11 3 33 21.4 x 2.31 We have 1 dp from 21.4 and 2 dp from 2.31 giving a total of 3 dp Putting the decimal point in gives 49.434 0.03 x 1.1 We have 2 dp from 0.03 and 1 dp from 1.1 giving a total of 3 dp Putting the decimal point in gives 0.033 13 You should always perform a rough check to make sure your answer is of the correct order. Example 20.42 x 3.12 2042 312 612600 We have 2 dp from 20.42 and 2 dp from 3.12 giving a total of 4 dp 20420 4084 637104 Putting the decimal point in gives 63.7104 As a rough check 20.42 is approximately 20 and 3.12 is approximately 3 So our answer should be about 60, which it is. Dividing decimals To get a method for this operation we use the idea of equivalent fractions. (Remember we can produce a fraction equivalent to a given fraction by multiplying (or dividing) the numerator and denominator by the same number) 5.39 ÷ 1.1 = 5.39 1.1 Now multiply numerator and denominator by 10 to produce 53.9 and we can now perform the usual long division 11 Example 11 4.9 53.9 So that 5.39 = 4.9 1.1 As with multiplication, do a rough check to make sure your answer is of the correct order. Example ie. 0.0325 ÷ 0.013 0.0325 0.013 14 Multiply numerator and denominator by 1000 to produce 32.5 and then perform the long division. 13 2.5 32.5 13 Once again a rough check shows the answer is of the correct order. As with multiplication of decimals we can abbreviate the method to: Move the decimal point in the denominator to produce a whole number Move the decimal point in the numerator the same number of places Perform the long division Example Find 0.275 0.25 This becomes 27.5 (two places in the numerator and denominator) 25 25 1.1 27.5 A rough check shows the answer is of the correct order Find 2.405 0.37 This becomes 240.5 (two places in the numerator and denominator) 37 37 6.5 240.5 Once again a rough check shows the answer is of the correct order 15 Decimals Exercise 1. Express the following in terms of hundreds, tens, units, tenths etc: a) 125.9 b) 87.03 c) 102.065 2. Write these numbers in figures: a) One unit, six tenths and one thousandth b) Five tens and five tenths c) Three hundreds, six units, nine hundredths and one thousandth 3. Evaluate the following: a) 18 × 10 b) 1.4 × 10 c) 0.02 × 10 d) 26.8 × 100 e) 2.09 × 100 f) 3.94 × 100 g) 2.1 × 1000 h) 12.9 × 1000 i) 1.08 × 1000 4. Evaluate the following: a) 18 10 b) 1.4 10 c) 0.02 10 d) 26.8 100 e) 2.09 100 f) 3.94 100 g) 2.1 1000 h) 12.9 1000 i) 1.08 1000 5. Find: a) 2.54 ÷ 0.2 b) 34.56 ÷ 0.9 d) 30.72 ÷ 2.4 e) 0.085 ÷ 0.025 c) 18.48 ÷ 1.2 Decimals Exercise - Answers 1. a) one hundred, two tens, five units and nine tenths b) eight tens, seven units, and three hundredths c) one hundred, two units, six hundredths and five thousandths 2. 3. a) 1.601 a) 180 f) 394 b) 50.5 b) 14 g) 2100 c) 306.091 c) 0.2 h) 12900 16 d) 2680 i) 1080 e) 209 4. 5. a) 1.8 f) 0.0394 a) 12.7 b) 0.14 g) 0.0021 b) 38.4 c) 0.002 h) 0.0129 c) 15.4 d) 0.268 i) 0.00108 d) 12.8 e) 0.0209 e) 3.4 Ratio Ratio describes the relationship between two quantities. Here we have 3 grey squares and 2 white squares. We can say that the ratio of grey squares to white squares is 3 to 2. This is usually written 3:2 where the colon replaces the ‘to’. 3:2 means that for every 3 items of the first type we have 2 items of the second. Similarly the ratio of white squares to grey squares is 2:3. In the top part of this diagram, we have 16 grey squares and 8 white squares. The ratio of grey squares to white squares is 16:8. However, as can be seen from the bottom part of the diagram, in each row we have 4 grey squares for each 2 white squares. This means that a ratio of 16:8 is the same as a ratio of 4:2. We have cancelled down the ratio by dividing both sides by a common factor (in this case 4). Looking at the ratio 4:2, we can see that 4 and 2 have a common factor of 2. This means that the ratio can be cancelled down further (as we did with fractions in the fractions section). So ‘for every 16 grey we have 8 white’ becomes: The ratio of grey to white is 16:8 This is the same as 4:2 Which is the same as 2:1. So the ratio of grey to white, is 2:1. 17 Using Ratios Examples 1. The small intestine is about 20 feet in length. If the ratio of the small intestine to the large intestine is 4:1 how long is the large intestine? We have small:large ≡ 4:1 meaning to every 4 feet of small intestine we have 1 foot of large. So that for 20 feet of small intestine we must have 5 feet of large. The large intestine is about 5 feet long. 2. Solution X is made from the contents of bottles A and B in the ratio of 3:2. We have already measured out 600mL of A. How many mL of B are required to make up X? 3:2 means that for every 3 parts of A we need 2 parts of B. We have 600mL of A. This is the same as 3 parts of 200mL each. To make up the solution we need 2 parts of B. So we need 2 x 200mL = 400mL. Ratios can also be linked to fractions. Examples 1. The ratio of drug A to water in a solution is 1:4. This means that for every part of A we need four parts of water. Alternatively, it means that for every 5 parts of the solution, 1 is A and 4 are water. So, 15 of the solution is A. 2. The ratio of A to B in a solution is 3:4. This means that for every 3 parts of A there are 4 parts of B. It also means that out of every 7 parts, 3 are A and 4 are B. So, 73 of the solution is A and 74 is B. 18 Note Some drugs may be labelled by ratios of milligrams to millilitres; in these situations the units are not the same on both sides. Always check labels carefully. Also 10mg per mL may be written 10mg/mL. Ratio Exercise 1. For the following diagrams, state i) the ratio of grey to white; ii) the ratio of white to grey: a) b) c) d) If possible cancel the ratios down to their simplest form. 2. Draw diagrams to represent the following ratios: a) 1:3 b) 3:5 c) 6:7 3. Write the following ratios in their simplest forms a) 12:8 b) 5:15 c) 28:7 4. The ratio on ward X of male patients to female patients is 2:5. a) If there are 6 male patients, how many female patients are there? b) If there are 20 female patients, how many male patients are there? 5. Medication Q is made up of solutions A, B and C. To make 50 mg of the medication you need 10mL of A 20mL of B 5mL of C a) What is the ratio of: i) A to B? ii) B to C? iii) C to A? b) If you needed to produce 100mg of Q how many mL of A, B and C would you need? c) There are 40mL of A left. i) What is the maximum dosage of Q that you can produce? ii) What quantities of B and C are needed to produce this dose? 6. For the following ratios of A:B, state what fraction of the solution is A and what fraction of the solution is B. Cancel down where possible. a) 2:6 b) 1:8 c)12:3 d) 2:3 19 Ratio Exercise – Answers a) i) 5:2 c) i) 3:3 = 1:1 2. a) ii) 2:5 ii) 3:3 = 1:1 b) 3. a) 3:2 4. a) 15 women 5. a) i) 10:20 = 1:2 b) 20mL of A c) i) 200mg 6. a) A. 82 14 c) A. b) i) 1:4 d) i) 3:2 12 15 4 5 ii) 4:1 ii) 2:3 c) b) 1:3 b) 8 men ii) 20:5 = 4:1 40mL of B ii) 80mL of B B. 86 34 B. 3 15 c) 4:1 iii) 5:10 = 1:2 10mL of C 20mL of C b) A. 19 B. 89 1 5 d) A. 20 2 5 B. 3 5 Percentages ‘Per cent’ literally means ‘per hundred’, so percentage is concerned with parts of a hundred. The symbol % is used to denote percentages. Some commonly used percentages are: 100% of something means the whole amount. (Literally 100 per 100) 50% of something means that you are looking at half of it, as 50 is half of 100. 10% of something means that you are looking at a tenth of it as 10 is a tenth of 100. We can work out percentages in many different ways. Two of the methods are detailed below. Method 1- Using Fractions As percentages are closely linked to fractions, we can use this fact to help with our calculations. We know that 50% means ‘50 out of a hundred’, so we can write this as 50 1 100 in the same way as we know that 1out of 2 can be written as 2 . The following table shows the fraction form of some common percentages: Percentage Fraction 100% 50% 25% 10% 5% 1% Simplified Fraction 100 100 50 100 25 100 10 100 5 100 1 100 1 1 2 1 4 1 10 1 20 1 100 You may wish to perform the cancelling down yourself to check the final column. 21 The general procedure for converting a percentage (say 15%) into a fraction is: Write the percentage as a fraction of 100 i.e. Cancel the fraction down to its simplest form. In this case we can divide top and bottom by the common factor, 5. 3 When the fraction is in its simplest form, we are done. 15%= 20 15 100 Cancelling the fraction down means that any subsequent calculation we perform uses the smallest possible numbers and is thus easier to work out. When we have converted our percentage to a fraction it is quite simple to use. Example Find 10% of 50. 10% is the same as So 10% of 50 = 501 10 1 10 1 10 (from the table). ×50 as we first multiply by the numerator. 50 5 as 50 and 10 have a common factor of 10 10 1 =5 Example Find 30% of 25. 30 3 30%= 100 10 3 30% of 25 =25× 10 253 10 75 10 As 75 and 10 have a common factor of 5, we can cancel the fraction down 75 10 15 2 This is an improper fraction or top heavy fraction, so we convert it into a mixed number. =7 Method 2 - Using Decimals As the number 1 is used to represent a whole, we can also use it to represent 100%. We know that 50% is half of 100%, so 50% of 1 must be half of 1, which as a decimal is 0.5. The following table shows the decimal form of some common percentages: Percentage 100% 50% 25% Decimal 1 0.5 0.25 22 10% 5% 1% 0.1 0.05 0.01 The general procedure for converting a percentage (say 15%) into a decimal is: Take the numerical value of the percentage, in this case 15, and divide it by 100. So 15% = 0.15, 17% = 0.17, 37% = 0.37 Example Find 10% of 50. 10÷100 = 0.1 so 10% of 50 = 0.1×50 = 5 Notice that this result is the same as the one we found earlier, using fractions. Both methods will give the same answer for any percentage problem. Note In calculating medicines, it is vital that your calculations are accurate. A decimal point in the wrong place can make a large difference to a dose. For this reason it is always a good idea to check your results, preferably by performing the calculation again using a different method, or by performing it in reverse. More Examples John weighs 120lbs and is 6ft 1in He is in hospital and cannot leave until he has increased his weight by 25%. How much must he weigh before he is allowed to leave? The question asks for the total weight after the gain. To start off we need to know how much he needs to gain. He currently weighs 120lbs. We need to find 25% of 120 Method 1 - Fractions 25 205 14 by cancelling 25% 100 1 4 × 120=30 so 25% of 120 is 30 His total weight will be 120+30=150 150 lbs Method 2 - Decimals 25 0.25 25% 100 0.25×120=30 His total weight will be 120+30=150 150 lbs An alternative method is to notice that his total weight will be 100% of his original weight + 25% of his original weight. So his eventual weight will be 125% of his original weight. This means that we can shorten the above calculations: 125 125% 100 25 20 54 by 125 1.25 125% 100 23 cancelling 5 4 × 120=150 His total weight will be 150 lbs 1.25×120=150 His total weight will be 150 lbs Increasing by a percentage Example A patient weights 150 kg. They have a 12% weight gain. What is his new weight? Method 1 Find out what 12% of 150 is and add that to the original weight. 12% = = 0.12 And 0.12 x 150 = 18 So that 150 + 18 = 168 The patient’s new weight is 168 kg Method 2 Notice that if we add 12% to the original We now have 112% 1.12 x 150 = 168 As above the patient’s new weight is 168 kg Decreasing by a percentage Example The dose of a drug given to a patient is to be reduced by 15%. If the patient had been originally prescribed 300 mg of drug A what is the new dosage in mg? Method 1 Find out what 15% of 300 is and subtract that from the original dose 15% = = 0.15 And 0.15 x 300 = 45 24 So that 300 – 45 = 255 The new dosage is 255 mg Method 2 Notice that if we reduce the dosage by 15% We have 85% left 85% = 0.85 0.85 x 300 = 255 As above, the new dosage is 255 mg Always check that your answer makes sense. A good check is to perform your calculation in reverse, so if you’ve found 25% of something, multiply it by 4 and you should have your original quantity back. 25 Percentages Exercise 1 1. Express as i) a fraction (simplify if possible), ii) a decimal a) 20% b) 30% c) 45% e) 9% f) 12% g) 84% d) 95% h) 29% 2. Using the method of your choice, evaluate the following: a) 20% of 15 b) 30% of 10 c) 45% of 200 d) 95% of 100 e) 9% of 300 f) 12% of 50 g) 84% of 25 h) 29% of 300 3. A baby’s weight has increased since birth by 10%. When it was born it weighed 3kg. What is its new weight? 4. A young adult’s height was measured and found to be 1.3m. They grow by 10% over the next year. What is their new height? 5. A patient loses 7% of their body weight after surgery. If they originally weighed 195 kg what is their new weight? For extra help with Percentages consult Mathematics leaflets ‘Fractions, Decimals and Percentages: how to link them’ and ‘Percentages’ available on the web at www.hull.ac.uk/studyadvice Percentages Exercise 1 - Answers 1. a) e) 20 100 9 100 2. a) 3 e) 27 102 15 0.2 0.09 b) f) 30 100 b) 3 f) 6 12 100 103 0.3 6 50 3 25 c) g) 0.12 3. New weight is 3.3kg or 3300g 4. 1.43m 26 45 100 9 20 c) 90 g) 21 84 100 42 50 0.45 21 25 0.84 d) h) 95 100 29 100 d) 95 h) 87 19 20 0.95 0.29 5. 181.35 kg Percentage increase/decrease We often need to find the percentage increase or decrease in a patient’s weight. To do this we use the formula: Change in Weight x 100 Original Weight Example: A patient who originally weighed 50kg loses 2 kg. What is her percentage weight loss? Her change in weight is 2 kg and her original weight is 50 kg. So we have 2_ x 100 = 4 50 This represents a 4% weight loss. A patient who originally weighed 125 kg now weighs 135 kg. What is his percentage weight gain? Here the change in weight is 10 kg and the original weight is 125 kg. So that we have 10__ x 100 = 8 125 This represents an 8% weight gain. 27 Percentages Exercise 2 Find the weight gain/loss of the following patients. a) Weight originally 80 kg, final weight 92 kg b) Weight originally 60 kg, final weight 63 kg c) Weight originally125 kg, final weight 120 kg d) Weight originally 200 kg, final weight 195 kg e) Weight originally 250 kg, final weight 245 kg Percentages Exercise 2 – Answers a)15% weight increase b) 5% weight increase c) 4% weight decrease d) 2.5% weight decrease e) 2% weight decrease 28 Body Mass Index (BMI) The BMI provides a simple numeric measure of a person’s ‘fatness’ or ‘thinness’ which allows healthcare professionals to discuss over and underweight problems objectively. The current settings are: BMI < 20 – Underweight 20 < BMI < 25 – Optimum weight 25 < BMI < 30 – Overweight BMI > 30 – Obese BMI > 40 – Morbidly obese BMI is calculated by dividing the person’s weight (in Kg) by their height 2 (in metres). The formula is written W H2 Example Find the BMI of a patient who weighs 75 kg and is 1.42 m tall BMI = 75 / (1.42 x 1.42) = 34.72 To the nearest whole number this is 35, therefore this patient is in the obese range. Find the BMI of a patient who weighs 93 kg and is 1.95m tall BMI = 93 / (1.95 x 1.95) = 24.46 To the nearest whole number this is 24, therefore this patient is in the optimum weight range. Body Mass Index Exercise with answers Find the BMI of the following patients to the nearest whole number a) Weight 80 kg, height 1.83m b) Weight 115 kg, height 2.00m c) Weight 78 kg, height 1.54m (24) (29) (33) d) Weight 62 kg, height 1.8m e) Weight 132 kg, height 1.64m 29 (19) (49) Averages The average or the mean of a set of numbers is just the value you get after adding the set of numbers up and dividing by how many numbers you have. Examples 1. Find the average of 2, 6, 4, 8, 5 2+6+4+8+5 = 25 =5 The average is 5 2. If a patient’s oral fluid intake on successive days is 120 mL, 200 mL 140 mL and 260 mL, what was the average intake over 4 days? 120+200+140+260 = 720 = 180 The average intake is 180 mL Averages Exercise 1. A patient’s pulse was taken every 30 minutes over 2 hours It was found to be 110, 105, 95 and 90 What is the average pulse rate over the 2 hours? 2. A patient’s temperature was taken every 30 minutes over 4 hours. It was 38°C, 38°C, 38.5°C, 39.1°C, 38.4°C, 38.1C°, 37.4°C, and 42.1°C What is the average temperature over: a) The first two hours b) The second two hours Averages Exercise 1. 100 2. a) 38.4°C b) 39.0°C 30 Unit Conversion In your chosen field you are likely to need to convert weights and volumes from one unit to another. Metric Measurements of Weight Name Kilogram Gram Milligram Microgram Nanogram Abbreviation kg g mg mcg ng Notes Approx. the weight of a litre of water One thousand grams to a kilogram One thousand mg to the gram One million mcg to the gram One thousand ng to the mcg Conversion Chart Number of Kilograms ÷1000 x 1000 Number of Grams ÷1000 x 1000 Number of Milligrams ÷1000 x 1000 Number of Micrograms ÷1000 x 1000 Number of Nanograms 31 As we move down the diagram the arrows are on the right and we move the decimal point three places to the right. As we move up the diagram the arrows are on the left and we move the decimal point three places to the left. Metric Measurements of Liquids Name Litre Millilitre Abbreviation Notes L An upper case L mL One thousand millilitres to a litre Conversion Chart Number of Litres ÷1000 x 1000 Number of Millilitres There is also the centilitre (cL), so named as there are a hundred of them in a litre. A single centilitre is equivalent to 10mL. Centilitres are normally used to measure wine. DO NOT USE A LOWER CASE L AS AN ABBREVIATION FOR LITRES. There is a chance of misreading 3l as thirty one (31) when it should be 3L. Always use L even in mL! Examples 1. Convert 575 millilitres into litres. From the diagram, we see that to convert millilitres to litres, we divide the number of millilitres by 1000. So we have 575÷1000=0.575 litres 2. Convert 2.67 litres into millilitres. To convert litres to millilitres we multiply the number of litres by 1000. So we have 2.67×1000=2670 millilitres Estimation Always look at the answers you produce to check they are sensible. A good way to do this is to estimate the answer. 32 In Example 1 above we can use our knowledge of litres and millilitres to estimate the result. We have 575 millilitres. If we had 1000 millilitres we would have a litre. Half a litre would be 500 millilitres, so our result will be a little over half a litre. Conversions of lbs ⇾ kg, kg ⇾ lbs It is sometimes necessary to change from imperial units to metric units and vice versa. The method is shown below: Weights in kg x 2.2 = weights in pounds. A patient weighs 124 kg, what is this in pounds (lbs)? 124 x 2.2 = 272.8 lbs Weights in pounds ÷ 2.2 = weights in kg. A patient weighs 212 lbs, what is this in kg? 212 ÷ 2.2 = 96.37 (2dp) kg 33 Unit Conversion Exercise 1 1. Copy and complete the following, using the tables and diagrams a) 1 kilogram = ____ grams b) 1 gram = ____ milligrams c) 1 gram = ____ micrograms d) 1 microgram = ____ nanograms e) 1 litre = ____ millilitres 2. Convert the following into milligrams a) 6 grams b) 26.8 grams c) 3.924 grams d) 405 grams 3. Convert the following into grams a) 1200mg b) 650mg c) 6749mg d) 3554mg 4. Convert the following into milligrams a) 120 micrograms b) 1001 micrograms d) 12034 mcg c) 2675 micrograms 5. Convert the following: (you may find it easier to work out the answers in two stages): a) 1.67grams into micrograms b) 0.85grams into micrograms c) 125 micrograms into grams d) 6784 micrograms into grams e) 48.9 milligrams into nanograms f) 3084 nanograms into milligrams 6. Convert the following into litres a) 10 millilitres b) 132 millilitres c) 2389 millilitres d) 123.4 millilitres 7. Convert the following into millilitres a) 4 litres b) 6.2 litres c) 0.94 litres d) 12.27 litres 8. A patient needs a dose of 0.5 g of medicine A. They have already had 360mg. a) How many more mg do they need? b) What is this value in grams? c) A dose of 1400 mcg has been prepared. Will this be enough? 34 Unit Conversion Exercise 1 - Answers 1 a) 1kg=1000g d) 1 mcg=1000ng b) 1g=1000mg e) 1 litre=1000Ml c) 1g=1000000mcg 2 a) 6g=6000mg b) 268g=26.800mg d) 405g=405000mg 3 a) 1200mg=1.2g d) 3554mg=3.554g b) 650mg=0.65g c) 3.924g=3924mg c) 6749mg=6.749g 4 a)120mcg=0.12mg b) 1001mcg=1.001mg c)2675 mcg= 2.675mg d) 12034mcg=12.034mg 5 a) 1.67g=1670000mcg c) 125 mcg=0.000125g e) 48.9mg=48900000ng b) 0.85g=850000mcg d) 6784mcg=0.006784g f) 3084ng=0.003084mg 6 a) 10mL=0.01litres b) 132mL=0.132litres d) 123.4mL=0.1234 litres c) 2389mL=2.389litres 7 a) 4litres=4000mL b) 6.2litres=6200mL d) 12.27litres=12270mL c) 0.94litres=940mL 8 a) 140 milligrams b) 0.14 grams c) no, the correct dose would be 140000mcg 35 Dosage Calculations Working out a dosage in either tablets or liquids is straightforward. The formula used is always the same. What you want x What it’s in What you’ve got When working with tablets what it’s in is always one tablet. To calculate a dosage you must write down 3 numbers. They are: What you want – this is what is prescribed/ordered/required/needed by the patient. What you have got – this is what is available. What it’s in – this is either 1 when we are working with tablets or in mL when working with liquids. The order in which you write these down is not difficult to remember, if you think ‘The patient always comes first’ ie. What you want. Note: In order to use this formula, the units of ‘What you want’ and ‘What you’ve got’ must be the same, ie. both in mcg, or both in mg, or both in g. Examples 1. A patient needs 500mg of drug X per day. X is available in 125mg tablets. How many tablets per day does he need to take? What you want = 500mg What you’ve got = 125mg What it is in = one tablet } } The units are both the same So our calculation is x1=4 The patient needs 4 tablets a day. 2. We need a dose of 500mg of Y. Y is available in a solution of 250mg per 50mL. In this case, What you want = 500mg } both in mg 36 What you’ve got = 250mg } What it’s in = 50mL So our calculation is 500 × 250 50 =100 We need 100mL of solution. 3. We need a dose of 250mg of Z. Z is available in a solution of 400mg per 200mL. In this case, What you want = 250mg } both in mg What you’ve got = 400mg } What it’s in = 200mL So our calculation is 250 × 400 200 = 125 We need 125mL of solution. 4. A patient is prescribed 250mg of erythromycin IV. Stock on hand contains 1g in 10mL once diluted. What you want = 250mg What you’ve got = 1g What it’s in = 10mL The units of What you want are mg and the units of What you’ve got are g. They must be the same units. Both in mg 1g = 1000mg So: What you want = 250mg What you’ve got = 1000mg What it’s in = 10mL Both in g 250mg = 0.25g Our calculation is 250 x 10 = 2.5 1000 We need 2.5mL Our calculation is 0.25 x 10 = 2.5 1 We need 2.5mL = 0.25g =1g =10mL Medicine over Time Tablets/liquids This differs from the normal calculations in that we have to split our answer for the total dosage into 2 or more smaller doses. Example A child weighing 12.5kg is prescribed a drug which is to be given in four equally divided doses. The dosage the child requires is 100mg/kg body weight. The child requires 12.5 x 100mg = 1250mg of the drug. 37 So for four equally divided doses 1250 = 312.5 4 They need 312.5mg four times a day. Drugs delivered via infusion For calculations involving infusion, we need the following information: The total dosage required The period of time over which medication is to be given How much medication there is in the solution A patient is receiving 500mg of medicine X over a 20 hour period. X is delivered in a solution of 10mg per 50mL. What rate should the infusion be set to? Here our total dosage required is 500mg Period of time is 20 hours There are 10mg of X per 50mL of solution Firstly we need to know the total volume of solution that the patient is to receive. Using the formula for liquid dosage we have: 500 10 ×50=2500 so the patient needs to receive 2500mL. We now divide the amount to be given by the time to be taken: 2500 20 =125 The patient needs 2500mL to be given at a rate of 125mL per hour Note: Working out medicines over time can appear daunting, but all you need to do is work out how much medicine is needed in total, and then divide it by the amount of doses needed or the time over which it is to be given. Drugs labelled as a percentage Some drugs may be labelled in different ways from those used earlier. V/V and W/V Some drugs may have V/V or W/V on the label. V/V means that the percentage on the bottle corresponds to volume of drug per volume of solution i.e 15% V/V means for every 100mL of solution, 15mL is the drug. W/V means that the percentage on the bottle corresponds to the weight of drug per volume of solution. Normally this is of the form ‘number of grams per number of millilitres’. So in this case 15% W/V means that for every 100mL of solution there are 15 grams of the drug. 38 If we are converting between solution strengths, such as diluting a 20% solution to make it a 10% solution, we do not need to know whether the solution is V/V or W/V. Examples 1. We need to make up 1 litre of a 5% solution of A. We have stock solution of 10%. How much of the stock solution do we need? How much water do we need? We can adapt the formula for liquid medicines here: What we want × What we want it to be in What we’ve got We want a 5% solution. This is the same as 5 100 We’ve got a 10% solution. This is the same as or 201 . 10 100 or 1 10 . We want our finished solution to have a volume of 1000mL. Our formula becomes 1 20 1 10 ×1000 = 201 × 101 ×1000 (using the rule for dividing fractions) = 12 ×1000=500 . We need 500mL of the A solution. Which means we need 1000-500=500mL of water. (Alternatively you can use the fact that a 5% solution is half the strength of a 10% solution to see that you need 500mL of solution and 500mL of water) 2. You have a 20% V/V solution of drug F. The patient requires 30mL of the drug. How much of the solution is required? 20% V/V means that for every 100mL of solution we have 20mL of drug F. Using our formula: What you want × What it’s in What you’ve got This becomes 30 20 ×100=150 We need 150mL of solution. 3. Drug G comes in a W/V solution of 5%. The patient requires 15 grams of G. How many mL of solution are needed? 39 5% W/V means that for every 100mL of solution, there are 5 grams of G. Using the formula gives us 15 5 ×100=300 300mL of solution are required. Note In very rare cases, a drug may be labelled with a ratio. If this is the case, refer to the Drug Information Sheet for the specific medication in order to be completely sure how the solution is made up. Dosage Calculations Exercise 1 1. How many 30mg tablets of drug B are required to produce a dosage of: a) 60mg b) 120mg c) 15mg d) 75mg 2. Medicine A is available in a solution of 10mg per 50mL. How many mL are needed to produce a dose of: a) 30mg b) 5mg c) 200mg d) 85mg 3. Medicine C is available in a solution of 15 micrograms per 100mL. How many mL are needed to produce a dose of: a)150mcg b) 45mcg c)30mcg d) 75mcg 4. Medicine D comes in 20mg tablets. How many tablets are required in each dose for the following situations: a) total dosage 120mg , 3 doses b) total dosage 60mg, 2 doses c) total dosage 100mg, 5 doses d) total dosage 30mg, 3 doses 5. At what rate per hour should the following infusions be set? a) Total dosage 300mg, solution of 25mg per 100mL, over 12 hours b) Total dosage 750mg, solution of 10mg per 30mL, over 20 hours c) Total dosage 450mg, solution of 90mg per 100mL, over 10 hours 6. Drug B comes in a 20% V/V stock solution. i) How much of the solution is needed to provide: a) 50mL of B b) 10mL of B c) 200mL of B ii) How would you make up the following solutions from the stock solution? a) Strength 20% volume 1 litre b) Strength 10% volume 750mL iii) What strength are the following solutions? a) Volume 1 litre, made up of 600mL stock solution, 400mL water b) Volume 600mL, made up of 300mL stock solution, 300mL water 7. Drug C comes in a 15% W/V stock solution. i) How much of the solution is needed to provide: 40 a) 30g of C b) 22.5g of C c) 90g of C ii) How would you make up the following solutions from the stock solution? a) Strength 5% volume 900mL b) Strength 10% volume 750mL iii) How many grams of C are in the following solutions? a) Volume 1 litre, made up of 400mL stock solution, 600mL water b) Volume 800mL, made up of 450mL stock solution, 350mL water Dosage Calculations Exercise 1 – Answers 1. a) 2 tablets b) 4 tablets c) 1 2 tablet d) 2 12 tablets 2. a) 150mL b) 25mL c) 1000mL d) 425mL 3. a) 1000mL b) 300mL c) 200mL d) 500mL 4. a) 2 tablets b) 1 12 tablets c) 1 tablet d) 5. a) 100mL per hour b) 112.5 mL per hour 1 2 tablet c) 50mL per hour 6. i) a) 250mL b) 50mL ii) a) 1 litre stock, no water iii) a) 600mL stock contains 120mL B 120 So 120mL in 1000mL= 1000 =12% c) 1 litre b) 375mL stock, 375mL water b) 300mL stock contains 60mL B 60 So 60mL in 600mL= 600 =10% 7. i) a) 200mL b) 150mL ii) a) 300mL stock, 600mL water iii) a) 60g b) 67.5g c) 600mL b) 500mL stock, 250mL water Dosage Calculations Exercise 2 A drug is available in 1 mg, 2 mg, 5 mg and 10 mg tablets. What is the best combination of these (i.e. the smallest number of tablets) to give the following dosages? Dosage 1 3 mg 2 7 mg 3 8 mg 4 10mg 5 11 mg Tablets required Number of tablets 41 6 14 mg Dosage Calculations Exercise 2 – Answers Tablets required Number of tablets Tablets required Number of tablets 1 1 mg & 2 mg 2 2 2 mg & 5 mg 2 3 1 mg, 2 mg & 5 mg 3 4 5 mg & 5 mg 2 5 5 mg, 5 mg & 1 mg 3 6 5 mg, 5 mg, 2 mg & 2 mg 4 Dosage Calculations Exercise 3 1. A solution contains furosemide (frusemide) 10 mg/mL. How many milligrams of frusemide are in a 2 mL b 3 mL c 5 mL of the solution? 2. A solution contains morphine hydrochloride 2 mg/mL. How many milligrams of morphine hydrochloride are in a 3 mL b 5 mL c 7 mL of the solution? 3. Another solution contains morphine hydrochloride 40 mg/mL. How many milligrams of morphine hydrochloride are in a 2 mL b 5 mL c 10 mL of this solution? 4. A suspension contains phenytoin 125 mg/5 mL. How many milligrams of phenytoin are in a 20 mL b 30 mL c 40 mL of the suspension? 42 5. A solution contains fluoxetine 20 mg/5 mL. How many milligrams of fluoxetine are in a 10 mL b 25 mL c 40 mL of the solution? 6. A suspension contains erythromycin 250 mg/5 mL. How many milligrams of erythromycin are in a 10 mL b 20 mL c 30 mL of the suspension? 7. A syrup contains chlorpromazine 25 mg/5 mL. How many milligrams of chlorpromazine are in a 10 mL b 30 mL c 50 mL of the syrup? 8. A mixture contains penicillin 250 mg/5 mL. How many milligrams of penicillin are in a 15 mL b 25 mL c 35 mL of the mixture? Dosage Calculations Exercise 3 – Answers All answers are in mg 1 a) 20 b) 30 c) 50 2 a) 6 b) 10 c) 14 3 a) 800 b) 200 c) 400 4 a) 500 b) 750 c) 1000 5 a) 40 b) 100 c) 6 a) 500 b) 1000 7 a) 50 b) 150 8 a) 750 b) 1250 160 c) 1500 c) 250 c) 1750 43 Dosage Calculations Exercise 4 In each example, you are given the prescribed dosage and the strength of stock on hand. Calculate the volume to be given: 1. Ordered: penicillin 500 mg On hand: syrup 125 mg/5 mL 2. Ordered: furosemide (frusemide) 40 mg On hand: solution 10 mg/mL 3. Ordered: morphine hydrochloride 100 mg On hand: solution 40 mg/mL 4. Ordered: paracetamol 180 mg On hand: suspension 120 mg/5 mL 5. Ordered: phenytoin 150 mg On hand: suspension 125 mg/5 mL 6. Ordered: erythromycin 1250 mg On hand: suspension 250 mg/5 mL 7. Ordered: fluoxetine 30 mg On hand: solution 20 mg/5 mL 8. Ordered: penicillin 1000 mg On hand: mixture 250 mg/5 mL 9. Ordered: chlorpromazine 35 mg On hand: syrup 25 mg/5 mL 10. Ordered: penicillin 1200 mg On hand: mixture 250 mg/5 mL 11. Ordered: erythromycin 800 mg On hand: mixture 125 mg/5 mL Dosage Calculations Exercise 4 - Answers All answers are in mL 1. 20 5. 6 9. 7 2. 4 6. 25 10. 24 3. 2.5 7. 7.5 11. 32 4. 7.5 8. 20 44 Dosage Calculations Exercise 5 Dosages of oral medications 1. A patient is ordered paracetamol 1 g, orally. Stock on hand is 500 mg tablets. Calculate the number of tablets required. 2. Ordered: codeine 15 mg, orally. Stock on hand: codeine tablets, 30 mg. How many tablets should the patient take? 3. A patient is ordered furosemide (frusemide) 60 mg, orally. In the ward are 40 mg tablets. How many tablets should be given? 4. How many 30 mg tablets of codeine are needed for a dose of 0.06 gram? 5. 750 mg of ciprofloxacin is required. On hand are tablets of strength 500 mg. How many tablets should be given? 6. A patient is prescribed 150 mg of soluble aspirin. On hand we have 300 mg tablets. What number should be given? 7. 450 mg of soluble aspirin is ordered. Stock on hand is 300 mg tablets. How many tablets should the patient receive? 8. 25 mg of captopril is prescribed. How many 50 mg tablets should be given? 9. The stock on hand of diazepam is 5 mg tablets. How many tablets are to be administered if the order is diazepam 12.5 mg? 10. Digoxin 125 mcg is ordered. Tablets available are 0.25 mg. How many tablets should be given? Check that you have used the same unit of weight throughout a calculation. Are both weights in milligrams (mg)? Or are both weights in micrograms (mcg)? 45 Dosage Calculations Exercise 5 - Anwers All answers are in tablets 1. 2 5. 2. 1 6. 3. 1 7. 4. 2 8. 9. 1 or 0.5 1 or 0.5 46 10. or 0.5 Dosage Calculation Exercise 6 Calculate the volume of stock required. Give answers greater than 1 mL correct to one decimal place; answers less than 1 mL correct to two decimal places. Ordered Stock ampoule 1. Morphine 12 mg 15 mg/mL 2. Calciparine 7000 units 25 000 units in 1 mL 3. Benzylpenicillin 1500 mg 1.2 g in 10 mL 4. Heparin 3000 units 5000 units/mL 5. Phenobarbitone 70 mg 200 mg/mL 6. Pethidine 80 mg 100 mg/2 mL 7. Buscopan 0.24 mg 0.4 mg/2mL 8. Digoxin 200 mcg 500 mcg in 2 mL 9. Furosemide (frusemide) 150 mg 250 mg in 5 mL 10. Ondansetron 5 mg 4 mg in 2 mL 11. Capreomycin 800 mg 1 g in 5 mL 12. Tramadol 120 mg 100 mg in 2 mL 13. Gentamicin 70 mg 80 mg in 2 mL 14. Vancomycin 800 mg 1 g in 5 mL 15. Morphine 7.5 mg 10 mg in 1 mL 16. Ceftriaxone 1250 mg 1 g/3 mL 17. Buscopan 25 mg 20 mg in 1 mL 18. Dexamethasone 3 mg 4 mg/mL 19. Vancomycin 1.2 g 1000 mg/5 mL 20. Naloxone 0.5 mg 0.4 mg/mL 47 Dosage Calculations Exercise 6 – Answers All answers are in mL 1. 0.8 6. 1.6 11. 4 16. 3.8 2. 0.28 7. 1.2 12. 2.4 17. 1.3 3. 12.5 8. 0.8 13. 1.8 18. 0.75 4. 0.6 9. 3 14. 4 19. 6 5. 0.35 10. 2.5 15. 0.75 20. 1.3 48 Dosage Calculations Exercise 7 Calculate the volume of stock to be drawn up for injection. 1. Pethidine 60 mg is ordered. Stock ampoules contain 100 mg in 2 mL. 2. An adult is ordered metoclopramide 15 mg, for nausea. On hand are ampoules containing 10 mg/mL. 3. A patient is prescribed erythromycin 250 mg, I.V. Stock on hand contains 1 g in 10 mL, once diluted. 4. Tramadol hydrochloride 80 mg is required. Available stock contains 100 mg in 2 mL. 5. A patient is ordered benzylpenicillin 800 mg. On hand is benzylpenicillin 1.2 g in 6 mL. 6. An adult patient with TB is to be given 500 mg of capreomycin every second day, I.M.I. Stock on hand contains 1 g in 3 mL. 7. Digoxin ampoules on hand contain 500 mcg in 2 mL. Digoxin 150 mcg is ordered. 8. Stock Calciparine contains 25 000 units in 1 mL. 15 000 units of Calciparine are ordered. 9. Penicillin 450 mg is ordered. Stock ampoules contain 600 mg in 5 mL. Dosage Calculations Exercise 7 - Answers All answers are in mL 1. 1.2 4. 1.6 7. 0.6 2. 1.5 5. 4 8. 0.6 3. 2.5 6. 1.5 9. 3.75 (3.8 to 1dp) 49 Dosage Calculations Exercise 8 1. An injection of morphine 8 mg is required. Ampoules on hand contain 10 mg in 1 mL. What volume is drawn up for injection? 2. Digoxin ampoules on hand contain 500 mcg in 2 mL. What volume is needed to give 350 mcg? 3. A child is ordered 9 mg of gentamicin by I.M.I. Stock ampoules contain 20 mg in 2 mL. What volume is needed for the injection? 4. A patient is to be given flucloxacillin 250 mg by injection. Stock vials contain 1 g in 10 mL, after dilution. Calculate the required volume. 5. Stock heparin has a strength of 5000 units per mL. What volume must be drawn up to give 6500 units? 6. Pethidine 85 mg is to be given I.M. Stock ampoules contain pethidine 100 mg in 2 mL. Calculate the volume of stock required. 7. A patient is to receive an injection of gentamicin 60 mg, I.M. Ampoules on hand contain 80 mg/2 mL. Calculate the volume required. 8. A patient is prescribed naloxone 0.6 mg, I.V. Stock ampoules contain 0.4 mg/2 mL. What volume should be drawn up for injection? Think about each answer. Does it make sense? Is it ridiculously large? Dosage Calculations Exercise 8 - Answers All answers are in mL 1. 0.8 4. 2.5 7. 1.5 2. 1.4 5. 1.3 8. 3.0 3. 0.9 6. 1.7 50 Suggested Reading Drug Calculations for Nurses-A Step By Step Approach Robert Lapham and Heather Agar ISBN 0-340-60479-4 Nursing Calculations Fifth Edition J.D. Gatford and R.E.Anderson ISBN 0-443-05966-7 Disclaimer Please note that the author of this document has no nursing or medical experience. The topics in this leaflet are dealt with in a mathematical context rather than a medical one. We would appreciate your comments on this worksheet, especially if you’ve found any errors, so that we can improve it for future use. Please contact the Maths Skills Adviser by email at skills@hull.ac.uk The information in this leaflet can be made available in an alternative format on request using the email above. 51