ACCESSORY ORCANS OF THE f[l| SKIN 7L Form a medical word that means an inflammation of the skin: / Myc/o/dermat/itis,an inflammation of the skin, @ : is caused by a i E The combining form trich/o refers to t}'e hai,r Construct medical terms meaning H F T È à disease of the hair: r .á abnormal condition of the hair: Ë ü iI Combine úich/o .| myc * -osis to form a medical term that means an abnormal condition of the hair caused by a fungus: @| a' ä # /- Wl pil/o /_ Another combining form for the hair is pillo. Whenever you or tncln/o in a word, you will know it refers to the see Pil/o/cyst/ic refers to a d.erm/ord cyst containing hair. The @ element in this frame that refers to hair is in this frame that means resembling is _. /-; f[p| the element Label the structures of the fingernail in Figure 3-B as you read the following material. Each nail is formed in the (l) nail root and is composed of keratin, a hard fibrous protein, which is also the main component of hair. As the nail grows from a (2) matrix of active cells beneath the (3) cuticle, it stays attached and slides forward over the epithelial layer called the (4) nail bed. Most of the (5) nail body appears pink because of the underlying blood vessels. The (6) lunula is the crescent-shaped area at the base of the nail. It has a whitish appearance because the vascular tissue underneath does not show through. (2',) (s) (6) (3) Figure 5-5 Structure of a fingernail. 72 cHAprER J. tNTEcuMENTARy sysTEM Here is a revíew of the three basic rules of word buílding. Rule l: A word root links a suffix that begins with a vowel. Rule 2: A combining form (root + o) links a suffix that begins with a consonant. Rule 5: A combining form (root + o) links a root to another root to form a compound word. This holds true even if the next root begins with a vowel. EI The combining form onych/o refers ro the zøil(s). Form medical words meaning tumor of the nail (or nailbed): disease / of the nails: ffl The term malacia refers to an abnormal softening of tissue. This term also is used in words as a suffix. Build a word with the suffix -malacia that means softening of the nail(s): /- / ][| The nails become white, opaque, thickened, and brittle when a person has a disease called onych/o/myc/osis. Identif the word elements in onydn/o/myc,/osis that mean nail: fungus: abnormal condition: @ When you see the term onych/o/myc/osis in a medical charr, you will know it means a fungus infection of the The noun suffix -derma also is used to denote skin. Aperson @ with excessive dryness of skin has a condition called xer/o/derm,a. From xer,/o /derma, identify the combining form that means dry: /-. f@ Jne surnx -cere rerers to a or -' CELL p' 75 Combining Forms Denoting Colors Wl Examine the combining forms and their meanings that denote color in the left-hand column below Examples of medical terms with their defrnitions are provided in che middle column. In che far right-hand column of this frame, use a slash to break down each word into its basic elements. Combining Form MedicalTerm Word Breakdown albin/o: white albinism: white cond,ition albinism cyan/o: blue cyanoderma: blue shin cyarroderma erythr/o: red erythroderma: erythroderma leuk/o: white leukoderma: white skin leukoderma melan/o: black melanoderma: blnck skin melanoderma xanth,/o: yellow xanthoma: yellnw tumor xanthoma red skin fftf,| The -a ending in cyanoderma, erythroderma, leukoderma, and melanoderma designates that these words are (adjectives, nouns) ![p| Use -derma to build medical words meaning /- skin that is red: /- skin that is black: / / skin that is yellow: skin that is dry: /- / Cells lpil You have already learned that a cell is the smallest basic unit of the human organism and that every tissue and organ in your body is made up of cells. gt/o EII and @/o/logy is the study of {yte are used to build words that designate a Cyt/o/logy is the study of -. 76 CHAPTER 3. INTEGUMENTARY SYSTEM |ff;II Use -cyte (cell) to form words meaning cell that is white: /- cell chat is black: cell that -Eil / /- cell that is red: is yellow: /- / /- / Leuk/o/cyt/o/penia, an abnormal decrease in white blood cells (WBCs), may be caused by an adverse drug reaction, radiatjon poisoning, or a pathological condition. One or all kinds of WBCs may be affected. The word leuk/o /cyt/o/penia is formed from the following word elements: The suffrx meaning decrease or deficiency is is form for cell is The combining form for white The combining EÐ /-. /-. A person with a decrease or deficiency in white blood cell production may be diagnosed with a condition known asleuk/o/penia or ffl The abbreviation forwhite blood count orwhite blood cell(s) is EE The suffix -emia is used in words to mean blood, cond,ition. Xanthr/emia, an occurrence of yellow pigment in the blood, literally means yellow |ff;Íl High cholesterol levels may cause small yellow tumors called EEEI Leuk,/emia is a progressive malignant disease of the bloodforming organs charactertzed by proliferation and development of immatureleuk/o/cytes in the blood and bone marrow Leuk,/emia literallY means white Lettk/o/cytes are A disease of unrestrained EÐ is called / blood cells. growth of immature white blood cells CELL 77 The activity of melan/o/cytes, which produce melanin, is genetically regulated and inherited. Local accumulations of melanin are seen in pigmented moles and freckles. Environmental and physiological factors also play a role in skin color. Locate the basal layer (stratum germinativum) @ in Figure 3-1. The absence of pigment in the skin, eyes, and hair is most likely due to an inherited inability to produce melanin. This lack of melanin results in the condition called albin/ism. A person with this condition is called an albino. f[[ When a person has a deficiency or absence of pigment in the skin, hair, and eyes due to an abnormality in production of melanin, the condition is known as /-. The number of melan/ o/cytes is about the same in all races. Differences in skin color are attributed to production of melanin. In people with dark skin, melan,/o/cytes continuously produce large amounts of melanin. In people with light skin, melan/ o/ cytes produce less @ Mehn,/oma is a malignant neoplasm that originates in the skin is and composed of melan/o/cytes. f,[| Form medical words that literally mean /- black cell: / black tumor: The lesion of melan/oma is characterized by its asymmetry, ![[| irregular border, and lack of uniform color. Malignant melan/oma is the most dangerous form of skin cancer because of its tendency to metastasize rapidly. The medical term that literally means black tumor is / Cyan/osis, also called cyan/o/d,mna, is caused by a deficiency of oxygen and an excess ofcarbon dioxide in the blood. A person who is rescued from drowning exhibits a dark bluish or purplish discoloration of the skin. This condition is known as cyan/osis or @ /- / 78 cHAprER 3. INTEcUMENTARy sysrEM f[!f Use -osis to develop medical words meaning / abnormal condition of blue (skin): abnormal condition of red (skin) abnormal condition of black (pigmentation) abnormal condition of yellow (skin) As you already know, the suffix -osis is used in words to mean abnormal condition. When -osis is used in a word related to blood, however, it means increase. The complete meaning of -osis is øbnorrnøI cond,ition; i,ncrease (used þi.mariþ with blood cell^s). Erythr/o/cyt,/osis is defined as an in red blood cells. @ Use leuk/o (whitQ to build a term meaning increase in white blood cells: /_ / / f[il Skin cancer is the most common type of cancer. There has been an increase in the rate of skin cancel mainly caused by exposure to ülttavi- olet rays in sunlight. Sun exposure, especially excessive tanning of the skin, can cause the lethal black tumor called / Other Related Terms Basal cell carcin/omais a type of skin cancer that affects the basal cell layer of the epidermis (see Figure 3-4). Metastasis is rare, but local invasion destroys underþing and adjacent tissue. This condition. occurs most frequently on areas of the skin exposed to the sun. @ A type of skin cancer that affects the basal layer is called basal cell Figure 5-4 Basal cell carcinoma (late stage). From Goldsmith, l-A, Lazarus, GS, and Tharp, MD: Adult and Pediatric Dermatology: A Color Guide to Diagnosis and Treatment, page 144, FA Davis, 1997, with permission. OTHER RELATED TERMS 79 Kaposi sarcoma, a malignant skin E@ tumor with patients who have acquired iñrmunodeficiency frequently associated syndromå (AIDS), is often fatal. Initially the tumor appears as a purplish brown terion. The abbreviation for acquired immunodeficiency syndrome is .---. A typ. of skin cancer associated with the AIDS virus is @ necr/osis. The combining form necr/o is used in words to denote d¿ath or Necr/ o/tic is a word that means pertaining to necr,/osis or Irltr The term necr,/osis is used to denote the death of areas of tissue or bone surrounded by healthy tissue. Cellular necr/osis means that the cells are lls. f I I. b tn iir'¡¡il @ Necr/o/cyt/ osis also means that the cells are @of blood Bony necr,/osis occurs when dead bone tissue results from the supply (for example, after a fracture) The term thar means abnormal condition of death is Ioss i.vl- il - IìEtf Gangrene is a form of necr,/osis associated with loss of blood supply. Before healing can take place, the dead matter must be removed. When there is an injury to blood flow, a form of necr,/ osis may develop that is known as @ oneself. In the English language, an autorlgraph In medical words, auto- is used as a prefix Autolh¡pnosis is hypnosis of one's _ Auto,/examination is an examination of one,s An auto/graft is skin transplanted from is a signature written by and means self, own. one,s lær A graft is tissue that is transplanted or implanted m a part of the body to repair a defect. Grafts done with tissue transplanted from the patient's own skin are called / 80 CHAPTER 3. INTEGUMENTARY SYSTEM Ad.erm/a/tome* is an instrument used to incise or cut. When the physician wants to graft a thin slice of skin, the physician asks for an instrument called a // Elf EÐ Skin transplanted from another person will not survive long, so from the patient's own skin. This surgical procedure is called an / a graft is performed using tissue transplanted r *The use of ¿ as the connecting vowel is an exception to the rule of using an o,