Marfan Syndrome
OVERVIEW:
As part of our unit on genetics, we have studied how recessive, dominant and sex-linked
traits are inherited. Some genetic conditions can also result from a condition known as trisomy
(3 chromosomes) that can occur during meiosis. To apply the knowledge that you have
learned, you will be researching the genetic condition known as Marfan Syndrome. Using the
internet, you will search for answers to a given set of research questions.
PRODUCT:
Refer to the handout of requirements of this project.
RESEARCH QUESTIONS:
1a) Is Marfan Syndrome caused by a dominant, recessive or sex-linked gene?
1b) What chromosome can this be found on?
2) What is the only possible way to inherit Marfan Syndrome?
3) What are the chances of a child with Marfan Syndrome having the disease if one
parent has Marfan Syndrome? (Use a Punnett Square to demonstrate)
4) What are the symptoms of Marfan Syndrome?
5) How is Marfan Syndrome diagnosed?
6a) How many people are diagnosed with Marfan Syndrome each year?
6b) Is Marfan Syndrome more common in any particular race or gender?
7a) How is Marfan Syndrome treated?
7b) What is the prognosis (future) for someone with Marfan Syndrome?
8) What is aorta dissection and how does this relate to Marfan Syndrome?
9) What can be done to prevent aortic dissection in people with Marfan Syndrome?
10a) What famous historical politician is thought to have had Marfan Syndrome?
10b) Why do historians believe this (what were their reasons)?
GRADING:
Refer to the handout of requirements of this project.
RESOURCES:
Lurgio Internet Encyclopedias
Internet sites from Wikipages
Classroom Time
Classroom Handouts
Personal Interviews (if possible)