LS3-1, W09
C. Lin,
Life Science 3 (LS3-1)
Introduction to Molecular Biology
Winter 2009 (January 5 – March 17, 2008)
Instructor:
Chentao Lin, Ph.D.
Professor of Molecular, Cell & Developmental Biology
Office: 3317 Life Science Building (LSB),
Phone: 310-206-9576, email: clin@mcdb.ucla.edu
Homepage: http://www.mcdb.ucla.edu/Research/Lin/
Lectures
Office Hours:
Textbook:
Course Web site:
Bruincast
MWF 2:00 am - 2:50 pm, LaKretz 110
MWF 3:00 am - 4:00 pm, LSB 3317
“Molecular Biology” (4th Edition, 2008) by R.F. Weaver.
http://www.lsic.ucla.edu/webapps/login/
http://www.bruincast.ucla.edu/
Exams & Grading:
Laboratory:
Midterm I (Tue. 1/27, 5-6:50pm, lectures 1-8)
Midterm II (Tue, 2/ 17, 5-6:50pm, lectures 9-17)
Final (Tue, 3/17, 6:30-9:30pm, lectures 1-28)
100pts
100pts
100pts
200pts
20%
20%
20%
40%
Lab & Discussion Sections: Discussion sections (wk 1, 3, 5, 7, 8) and Lab (wk 2, 4, 6, 9, 10)
will be lead by Drs. Gaston Pfluegl (Gaston@lsic.ucla.edu, 794-4113), Rhonda Murotake
(rhondam@lifesci.ucla.edu, 825-8860), and your TAs. See the “LS3 lab manual” for details.
Honor Section (LS89)
A honor section will be offered for the LS3-1 students who want to learn more about Mol. Biol.
In the honor sections, research papers cornering a specific biological question will be discussed.
LS89 will meet in LS3326, Friday, 4-6pm, starting week 3 (1/23/09).
Teaching Assistants:
Mariam Aghajan, maghajan@mednet.ucla.edu
Hume Stroud-Drinkwater, hstroudd@ucla.edu
Jenny Hernandez, hernandj@ucla.edu
Mary Clark, clarkm@ucla.edu
Shawn Jia, shawnjia@gmail.com
Minglei Zhao, mlzhao@ucla.edu
Genaro Villa, grvilla@ucla.edu
Administration:
Life Science Core Curriculum Office (LSB2305, Lily Yanez,
lyanez@lifesci.ucla.edu, or Mark Katayama, katayama@lifesci.ucla.edu) will address all
administrative issues.
LS3-1 (W2009) Syllabus
Week
Lecture
1
1
Monday, 1/5/09
Introduction
Chapter 1-3
2
Wednesday, 1/7
DNA and genome
Chapter 1-3
3
Friday, 1/9
RNA and Proteins
Chapter 1-3
4
Monday, 1/12
Molecular Biology Methods
Chapter 4-5
5
Wednesday, 1/14
Molecular Biology Methods
Chapter 4-5
6
Friday, 1/16
Molecular Biology Methods
Chapter 4-5
Monday, 1/19
Martin Luther King, Jr, Holiday
7
Wednesday, 1/21
Molecular Biology Methods
Chapter 4-5
8
Friday, 1/23 (lect 8) Molecular Biology Methods
Chapter 4-5
9
Monday, 1/26
Prokaryotic Transcription I
Chapter 6-8
Tuesday 1/27/09
(Midterm I, Lectures 1-8)
5:00-6:50pm
10
Wednesday, 1/28
Prokaryotic Transcription II
Chapter 6-8
11
Friday, 1/30
Prokaryotic Transcription III
Chapter 6-8
12
Monday, 2/2 (PO)
Eukaryotic Transcription I
Chapter 9-13
13
Wednesday, 2/4 (PO) Eukaryotic Transcription II
Chapter 9-13
14
Friday, 2/6 (PO)
Eukaryotic Transcription III
Chapter 9-13
15
Monday, 2/9
Eukaryotic Transcription IV
Chapter 9-13
16
Wednesday, 2/11
Eukaryotic Transcription V
Chapter 9-13
17
Friday, 2/13 (lec 17) Chromatin structure and Transcription
2
3
4
5
6
7
8
9
10
11
Date
Topics
Reading
Chapter 9-13
Monday, 2/16
Presidents’ Day Holiday
Tuesday 2/17/09
(Midterm II, Lectures 9-17)
5:00-6:50pm
18
Wednesday, 2/18
RNA processing I
Chapter 14-16
19
Friday, 2/20
RNA processing II
Chapter 14-16
20
Monday, 2/23
RNA processing III
Chapter 14-16
21
Wednesday, 2/25
Translation I
Chapter 17-19
22
Friday, 2/27
Translation II
Chapter 17-19
23
Monday, 3/2
Translation III
Chapter 17-19
24
Wednesday, 3/4
DNA Replication I
Chapter 20-21
25
Friday, 3/6
DNA Replication II
Chapter 20-21
26
Monday, 3/9
DNA Replication III
Chapter 20-21
27
Wednesday, 3/11
Genome structure and genomics I
Chapter 23-24
28
Friday, 3/13
Genome structure and genomics II
Chapter 23-24
Wednesday, 3/17
Final Exam (Lectures 1-17)
6:30- 9:30PM