LIFE SCIENCES 3 (LS 3.2)
Introduction to Molecular Biology, Spring 2010
Tue & Thu, 2-3;15pm, La Kretz 110
Dr. April Pyle & Dr. Randolph Wall
Lecture
Date
Topics
Reading
Pyle
Pyle
Pyle
Pyle
Pyle
Pyle
Pyle
Pyle
Pyle
Pyle
Wall
March 30
April 1
April 6
April 8
April 13
April 15
April 20
April 22
April 27
April 29
May 4
Pyle
Wall
Wall
May 5
May 6
May 11
Wall
Wall
Wall
Wall
Wall
May 13
May 18
May 20
May 25
May 27
Wall
Wall
Wall
June 1
June 3
June 9
Molecular Components
43-56
Protein structure
71-94
Protein function & Techniques
764-774
DNA Structure
101-126
DNA Replication
195-255
RNA structure
127-133
Transcription
377-414
Regulation of Prokaryotic Transcription 547-560
Regulation of Eukaryotic Transcription
589-631
Midterm Exam Review
Eukaryotic Genes & mRNA Processing 406-410, 415-425,
430-435, 452-453
Midterm Exam (5-7:50pm)
Translation I: Genetic Code & tRNA 457-469, 521-538
Translation II: Ribosomes & Protein 469-496, 502-503
Synthesis
Viruses & the New Central Dogma
783-794
Restriction Enzymes & DNA Mapping
739-746
Recombinant DNA Cloning & PCR
746-752
Screening Libraries & Microarrays
743-749, 662
Sequencing Genes & Genomes/The
641-655, 659,
Transcriptome & RNA Silencing
703-707, 753-764
Comparative Genomics
711-715
Final Exam Review
Final Exam (11:30-2:30pm)
Text: Molecular Biology of the Gene (Sixth Edition), Cold Spring Harbor Press.
J. D. Watson, T.A. Baker, S. P. Bell, A. Gann, M. Levine, & R. Losick
Note: LS3 is an impacted course. Students have up to Friday of Week 2 to
drop this course.
Instructors:
Dr. April Pyle
Dr. Randolph Wall
Office Hours:
Dr. Pyle (Tuesdays 3:30-5PM @ BSRB 277A)
Dr. Wall (Tuesdays 3:30-5PM @ Boyer 529)
TAs:
Feng, Jiaying (jiayingfeng@mednet.ucla.edu)
Huang, Tsung-Pai (James) (huangjames@ucla.edu)
Ulgherait, Matthew (mju24@ucla.edu)
Yang, Gang (Alvin) (yanggang03@gmail.com)
Yun, Jina (jinayun@ucla.edu)
Zhou, Xi (Josie) (xizhou@ucla.edu)
Websites:
http://www.lsic.ucla.edu/classes/spring10
http://lslab.lscore.ucla.edu
Lab Management: Dr. Gaston Pfluegl. Slichter 2875 (gaston@lifesci.ucla.edu)
LS Core Student Affairs Officers:
Lily Yanez. LS 2305 (lscore@lifesci.ucla.edu)
Jane Park. LS 2305 (lscore@lifesci.ucla.edu)
Grading:
Midterm Exam on 05/05 (5-6:50PM)
200 points
Labs
100 points
Final Exam on 06/09 (11:30-2:30PM)
200 points
(20 points of the final exam will pertain to lab material)
Total: 500 points
Make-up Policy:
No make up examination will be given. If you are unable to take an examination due
to illness or other emergency, you are responsible for contacting the Life Sciences
Core Curriculum Office located in LSB 2305 before the examination. You are
required to have written verification from a physician regarding the illness or
emergency.