Basic Medical Course II
Subject:
INTRODUCTION TO MEDICAL CHEMISTRY, 2013/2014
LECTURES:
T. Building, Lecture hall
Monday:
Thursday:
SEMINARS:
10-12 h
10-12 h
T. Building Seminar Room #1
SEMINAR I:
I.
Monday: 14-16h, Tuesday: 8-10, and 10-12 h; Wednesday: 10-12 and 12-14 h
SEMINAR II:
II.
Thursday:
12-14, 14-16, and 16-18 h
Friday: 8-10 and 12-14 h
Textbooks:
McMurry-Fay: Chemistry, 6th edition
Erdődi-Csortos: Organic Chemistry for Premedical Students
1st week
January 13-17
Monday: NO lecture, seminars ONLY
Seminars: Introduction to general chemistry. Elements. Symbols for
the elements. The SI system of measurement (McMurry pp. 1-25).
Thursday: Atoms. The structure of atoms. Nuclear arithmetic
Molecules and ions, compounds and mixtures (McMurry pp. 34-46).
2nd week
January 20-24
Monday: Chemical formulas. Empirical and molecular formulas
Naming chemical compounds. Chemical equations. Balancing
chemical equations. (McMurry pp. 46-47, 54-66, 75-78).
Thursday: Avogadro’s number and the mole. Atomic, molecular and
molar mass relationships Stoichiometry: chemical arithmetic.Yields of
chemical reactions. (McMurry pp. 79-92, 94-99).
3rd week
January 27-31
Monday: Light and the electromagnetic spectrum. Atomic spectra. The
Bohr model of the hydrogen atom. The quantum mechanical model of the
atom. Orbitals and quantum numbers. (McMurry pp.151-169).
Thursday: Self control test
1
4th week
February 3-February 7
Monday: Electron configurations and the periodic table. Classification
of the elements. Representative and transition elements. (McMurry
pp.169-176, 203-208)
Thursday: The sizes of atoms and ions. Ionization energy, electron
affinity (McMurry pp. 177-178, 187-197).
5th week
February 10-14
Monday: Chemical bonds: metallic, ionic and covalent bonds.
Electron-dot structures for molecular compounds and polyatomic ions
(McMurry pp. 859-863, 198-201, 217-235).
Thursday: Single and multiple covalent bonds. Molecular shapes: the
VSEPR model. Valence bond theory. Hybridization (McMurry pp. 236 249).
6th week
February 17-21
Monday: Intermolecular forces (McMurry pp.347-356).
Thursday: First control test
7th week
February 24-28
Monday: The gaseous state. Gases and gas pressure. The gas laws. The
ideal gas law. Stoichiometric relationships with gases. Kinetic-molecular
theory of gases (McMurry pp. 309-332).
Thursday: Liquid and solid states. Phase changes. Evaporation, vapor
pressure, boiling point. (McMurry pp. 357-363, 366-367, 370-377).
8th week
March 3-March 7
Monday: Solutions and their properties. Concentration of solutions.
Units of concentration: molarity, mass percent, molality. Dilution of
solutions. Some factors affecting solubility (McMurry pp.88-92, 393405).
Thursday: The chemistry of water. Ions in aqueous solution: electrolytes
and nonelectrolytes. Reactions in aqueous solution (McMurry 113-126).
9th week
March 10-14
Monday: Chemical equilibrium. The equilibrium constant. Factors that
alter the composition of an equilibrium mixture. (McMurry pp. 493-521).
Thursday: Second control test
10th week
March 17-March 21
Monday: Acids and bases. The pH in solutions of strong acids and strong
bases (McMurry pp. 539-551, 573-575).
Thursday: Equilibria in solutions of weak acids. Equilibria in
solutions of weak bases. (McMurry pp. 552-563).
11th week
March 24-28
Monday: Thermochemistry. Energy changes and energy conservation.
Internal energy and state functions. Expansion work. Energy and
enthalpy. The thermodynamic standard state. Enthalpies of physical and
chemical changes. Hess’s law (McMurry pp. 267-277, 281-285).
2
Thursday: Oxidation and reduction. Oxidation state. The activity series
of the elements. Balancing redox reactions. Galvanic cells (McMurry pp.
124-135, 681-694).
12th week
March 31-April 4
Monday: Discussion of general chemistry
Thursday: Third control test
13th week
April 7-11
Monday: Introduction to organic chemistry (Erdődi pp.1-18).
Thursday: Saturated hydrocarbons: alkanes (Erdődi pp. 19-36).
14th week
April 14-18
Monday: Cycloalkanes (Erdődi pp. 36-45).
Thursday: Unsaturated hydrocarbons: alkenes and alkynes (Erdődi pp.
46-61).
15th week
April 21-25 Easter!!
Monday: Easter
Thursday: Self control test
16th week
April 28-May 2 Thursday May 1!!
Monday: Aromatic compounds: the structure and properties of benzene
and its derivatives (Erdődi pp. 62-70).
Thursday: Holiday 1st May
17th week
May 5 -May 9
Monday: Heteroaromatic compounds. The reactions of benzene (Erdődi
pp. 70-84).
Thursday: Organic halogen compounds (Erdődi pp. 85-95).
18th week
May 12-16
Monday: Alcohols and phenols (Erdődi pp. 96-113).
Thursday: Important alcohols (Erdődi pp. 113-117). Ethers and organic sulfur
compounds (Erdődi pp. 118-134).
May 19-23
Monday: Fourth control test
Thursday: Aldehydes, ketones and quinones (Erdődi pp. 135-162).
19th week
20th week
May 26-30
Monday: Nitrogen containing organic compounds: the structure and
properties of amines. Basicity and reactions of amines (Erdődi pp. 163184).
Thursday: Heterocyclic amines. Amines of biological importance
(Erdődi pp. 185-199).
21st week
June 2-6
Monday: Carboxylic acids: classification and nomenclature (Erdődi pp. 200209).
Thursday: Fifth control test
3
22nd week
June 9-13 Pentecost
Monday:
Thursday: Properties of carboxylic acids. Important carboxylic acids. (Erdődi
pp. 209-221).
23rd week
June 16-20
Monday: Reactions of carboxylic acids. Substituted carboxylic acids
(Erdődi pp. 221-232).
Thursday: Carboxylic acid derivatives (Erdődi pp. 233-264).
24th week
June 23-27
Monday: Stereochemistry. Optical activity: properties of enantiomers
and diastereomers (Erdődi pp. 265-277, 285-288).Absolute and relative
configurations. (Erdődi pp. 278-284, 288-298).
Thursday: Sixth control test
14th January, 2014.
4