SIGMA-ALDRICH
Material Safety Data Sheet
Version 3.0
Revision Date 10/20/2009
Print Date 09/10/2010
1. PRODUCT AND COMPANY IDENTIFICATION
Product name
:
Phenylmagnesium bromide solution
Product Number
Brand
:
:
257117
Aldrich
Company
:
Telephone
Fax
Emergency Phone #
:
:
:
Sigma-Aldrich
3050 Spruce Street
SAINT LOUIS MO 63103
USA
+18003255832
+18003255052
(314) 776-6555
2. COMPOSITION/INFORMATION ON INGREDIENTS
Formula
CAS-No.
:
C6H5BrMg
EC-No.
Index-No.
Concentration
Bromophenylmagnesium
100-58-3
202-867-2
-
59.62 %
Diethyl ether
60-29-7
603-022-00-4
40.38 %
200-467-2
3. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards
Flammable liquid, Water Reactive, Target Organ Effect, Harmful by ingestion., Corrosive
Target Organs
Central nervous system, Liver, Kidney, Gastrointestinal tract, Skeletal muscle.
HMIS Classification
Health hazard:
Chronic Health Hazard:
Flammability:
Physical hazards:
3
*
3
2
NFPA Rating
Health hazard:
Fire:
Reactivity Hazard:
Special hazard.:
3
3
2
W
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Potential Health Effects
Inhalation
Skin
Eyes
Ingestion
May be harmful if inhaled. Material is extremely destructive to the tissue of the
mucous membranes and upper respiratory tract.
May be harmful if absorbed through skin. Causes skin burns.
Causes eye burns.
Harmful if swallowed. Causes burns.
4. FIRST AID MEASURES
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Continue rinsing eyes during transport to hospital.Rinse thoroughly with plenty of water for at least 15 minutes and
consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult
a physician.
5. FIRE-FIGHTING MEASURES
Flammable properties
Flash point
-40 °C (-40 °F) - closed cup
Ignition temperature
no data available
Suitable extinguishing media
Carbon dioxide (CO2) Dry powder
Extinguishing media which shall not be used for safety reasons
Water
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all
sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive
concentrations. Vapours can accumulate in low areas.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods for cleaning up
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth,
vermiculite) and place in container for disposal according to local / national regulations (see section 13). Do not flush
with water.
7. HANDLING AND STORAGE
Handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electrostatic charge.
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Storage
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully
resealed and kept upright to prevent leakage. Store in cool place.
Never allow product to get in contact with water during storage.
Light sensitive.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Components with workplace control parameters
Components
CAS-No.
Value
Diethyl ether
60-29-7
TWA
Remarks
Central Nervous System impairment Upper Respiratory Tract irritation
STEL
Control
parameters
400 ppm
500 ppm
Update
Basis
2007-01-01
USA. ACGIH Threshold
Limit Values (TLV)
2007-01-01
USA. ACGIH Threshold
Limit Values (TLV)
Central Nervous System impairment Upper Respiratory Tract irritation
TWA
400 ppm
1,200 mg/m3
1989-01-19
USA. OSHA - TABLE Z-1
Limits for Air Contaminants
- 1910.1000
STEL
500 ppm
1,500 mg/m3
1989-01-19
USA. OSHA - TABLE Z-1
Limits for Air Contaminants
- 1910.1000
TWA
400 ppm
1,200 mg/m3
1997-08-04
USA. Occupational
Exposure Limits (OSHA) Table Z-1 Limits for Air
Contaminants
The value in mg/m3 is approximate.
Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If
the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and
components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Hand protection
Handle with gloves.
Eye protection
Tightly fitting safety goggles. Faceshield (8-inch minimum).
Skin and body protection
Choose body protection according to the amount and concentration of the dangerous substance at the work
place.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end
of workday.
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9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Form
liquid
Safety data
pH
no data available
Melting point
no data available
Boiling point
no data available
Flash point
-40 °C (-40 °F) - closed cup
Ignition temperature
no data available
Lower explosion limit
no data available
Upper explosion limit
no data available
Density
1.134 g/mL at 25 °C (77 °F)
Water solubility
no data available
10. STABILITY AND REACTIVITY
Storage stability
Stable under recommended storage conditions.
Conditions to avoid
Heat, flames and sparks. Exposure to moisture.
Materials to avoid
Water, Oxidizing agents, Strong oxidizing agents, Strong acids, Alcohols, acids
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen bromide gas,
Magnesium oxide
Hazardous reactions
Vapours may form explosive mixture with air.
Reacts violently with water.
11. TOXICOLOGICAL INFORMATION
Acute toxicity
no data available
Irritation and corrosion
no data available
Sensitisation
no data available
Chronic exposure
IARC:
No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
ACGIH:
No component of this product present at levels greater than or equal to 0.1% is identified as
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a carcinogen or potential carcinogen by ACGIH.
NTP:
No component of this product present at levels greater than or equal to 0.1% is identified as
a known or anticipated carcinogen by NTP.
OSHA:
No component of this product present at levels greater than or equal to 0.1% is identified as
a carcinogen or potential carcinogen by OSHA.
Signs and Symptoms of Exposure
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin.,
spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis,
pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea
Potential Health Effects
Inhalation
Skin
Eyes
Ingestion
Target Organs
May be harmful if inhaled. Material is extremely destructive to the tissue of the
mucous membranes and upper respiratory tract.
May be harmful if absorbed through skin. Causes skin burns.
Causes eye burns.
Harmful if swallowed. Causes burns.
Central nervous system, Liver, Kidney, Gastrointestinal tract, Skeletal muscle.,
12. ECOLOGICAL INFORMATION
Elimination information (persistence and degradability)
no data available
Ecotoxicity effects
no data available
Further information on ecology
no data available
13. DISPOSAL CONSIDERATIONS
Product
Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and local environmental regulations. Contact a licensed
professional waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
DOT (US)
UN-Number: 3399 Class: 4.3 (3)
Packing group: I
Proper shipping name: Organometallic substance, liquid, water-reactive, flammable (Bromophenylmagnesium, Diethyl
ether)
Reportable Quantity (RQ): 248 lbs
Marine pollutant: No
Poison Inhalation Hazard: No
IMDG
UN-Number: 3399 Class: 4.3 (3)
Packing group: I
EMS-No: F-G, S-N
Proper shipping name: ORGANOMETALLIC SUBSTANCE, LIQUID, WATER-REACTIVE, FLAMMABLE (Diethyl
ether, Bromophenylmagnesium)
Marine pollutant: No
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IATA
UN-Number: 3399 Class: 4.3 (3)
Packing group: I
Proper shipping name: Organometallic substance, liquid, water-reactive, flammable (Diethyl ether,
Bromophenylmagnesium)
IATA Passenger: Not permitted for transport
15. REGULATORY INFORMATION
OSHA Hazards
Flammable liquid, Water Reactive, Target Organ Effect, Harmful by ingestion., Corrosive
DSL Status
All components of this product are on the Canadian DSL list.
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the
threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards
Fire Hazard, Reactivity Hazard, Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
Diethyl ether
CAS-No.
60-29-7
Revision Date
2007-03-01
CAS-No.
60-29-7
100-58-3
Revision Date
2007-03-01
CAS-No.
60-29-7
100-58-3
Revision Date
2007-03-01
Pennsylvania Right To Know Components
Diethyl ether
Bromophenylmagnesium
New Jersey Right To Know Components
Diethyl ether
Bromophenylmagnesium
California Prop. 65 Components
This product does not contain any chemicals known to the State of California to cause cancer, birth, or any other
reproductive defects.
16. OTHER INFORMATION
Further information
Copyright 2009 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only.
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a
guide. The information in this document is based on the present state of our knowledge and is applicable to the
product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the
product. Sigma-Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with
the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.
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