Biology Long Question Exercise for HKDSE (Supplement to Book 1-1st Edition) Supplement to Book 1 -1st Edition © Takka Education Books Co. All rights reserved. No part of this book may be reproduced in any form or by any means, including electronic copies, without the prior permission from the copyright owner. Takka Education Books Co. 德嘉教育出版社 CONTENTS Chapter 1 Molecules of life ......................................................... 3 Chapter 2 Cellular organisation .................................................. 5 Chapter 3 Movement of substances across a membrane ............... 7 Chapter 4 Enzymes ................................................................... 7 Answer ....................................................................................... 8 Chapter 1 3 Molecules of life 這本書主要修訂是在第一章大幅刪去 "molecular structure" (分子結構) 的部分, 原版第二冊 中的 "Energetic - respiration" 移到修訂版第一冊, 其餘變動不大。 Chapter 1 A) Molecules of life The following questions are removed from Chapter 1 of the previous edition: 1.9 1.11 1.13 1.15 1.17 1.18 1.19 1.20 1.21 1.22 1.27-(a) 1.28 1.31 1.33 1.35 1.36 1.37 1.39 1.41-(a) 1.44 1.58 1.59 1.63 1.64 These removed questions are chiefly related with the molecular structures of carbohydrates proteins, and fats. B) In the revised edition, biuret test for proteins was replaced by Albustix paper test. C) Three questions are added to Chapter 1. Proteins 1.1 Describe a test to find out if soybean contains protein. (4 marks) (這是原 1.25-c 的題目 , 答案中的 biuret test 改為 Albustix paper test.) 1.2 Globular proteins are proteins with a specific shape (conformation). Describe how globular proteins can have different shapes and how these shapes enable them to have different functions in a human body. (Description of fibrous protein is not required.) (13 marks) (This question requires answers in essay form. Some marks are given on the presentation of the answers, which should be logical and with coherent layout.) 4 Chapter 1 Molecules of life Food tests 1.3 The table below shows the results of some food tests on four foodstuffs. (這是原題目 1.49, 修訂版將原本 biuret test 改為 Albustix paper test.) Result of food test Foodstuff Colour on Albustix paper test Colour on Benedict’s solution test Appearance on emulsion test A blue-green blue milky B yellow blue milky C yellow brick-red clear D yellow blue clear (a) Name the food types in foodstuffs (i) A , (ii) B , and (iii) C as indicated by the results of the tests. (3 marks) (b) Describe a further test to find out if foodstuff D contains non-reducing sugar. (c) Describe a test to find out if starch is present in foodstuff C. (3 marks) (1 mark) Chapter 2 Chapter 2 5 Cellular Organisation Cellular organisation A) Question 2.10 is removed from the previous edition. B) Three questions have been added to Chapter 2. 2.1 Draw a labelled diagram to show the structures of a biological membrane, such as the plasma membrane. The following are some structures that you may have to include in your diagram. (7 marks) phospholipid 2.2 glycoprotein cholesterol carrier protein The vacuoles of the beetroot cells contain a red pigment. This red pigment would be released if the cell membrane and the vacuole membrane have been damaged. In an investigation, two beetroot cubes of similar size cut from a peeled beetroot were put separately in two test tubes (X and Y) containing the same volumes of alcohol but of different concentrations as shown in Diagram A. After 20 minutes, red colours of different intensities appeared in the alcohol as that shown in Diagram B. X Y X alcohol of different concentrations beetroot cube Diagram A: at the start beetroot cube Y red colour of different intensities Diagram B: after 20 minutes 6 Chapter 2 Cellular Organisation (a) From the result in Diagram B, explain which test tube contains alcohol with a higher concentration. (5 marks) (b) After two hours, it was found that the red colours in X and Y has the same intensity. Explain why. (2 marks) 2.3 At the 17th century with the invention of compound light microscopes, scientists at that time found that the semi-fluid materials inside the cells could carry out all life activities such as respiration, enzyme actions and cell divisions. They called this semi-fluid "protoplasm", which was believed to be the basis of life. After the invention of electron microscopes, scientists discovered that this semi-fluid actually contained even smaller structures, which they named them "organelles". On isolating these organelles, they confirmed that most life activities are actually carried out by these organelles. (a) From the above information, explain why protoplasm is a term that is no longer appropriate in modern biology. (1 mark) (b) Explain why electron microscope with a magnification of 20 000x can see cell structures in greater detail than a light microscope with the same magnification. (2 marks) (c) In the following table, elaborate on how the above information demonstrates the nature of science in the building of knowledge. (3 marks) Nature of Science (i) Science is based on existing evidence. (ii) Scientific knowledge is tentative and can be changed. (iii) New technology adds new knowledge to science. Elaboration Chapter 4 Chapter 3 A) 7 Enzyme Movement of substances across a membrane The following questions are removed from Chapter 3 of the previous edition: 3.6 3.8-(a) B) cm3 and dm3 are replaced by mL and L. C) No question is added to Chapter 3. Chapter 4 Enzymes A) The questions listed below are removed from Chapter 4. They are mainly those related with competitive and non-competitive inhibitions. 4.17 4.18 4.19 4.20 B) One question is changed in Chapter 4. 4.1 (這代替原版中的 4.17。) The diagram on the right shows an enzyme. X and Y are two kinds of molecules that can combine with the enzyme. X is the substrate. (a) Y Draw a circle on the diagram to indicate the active site. (1 mark) Enzyme (b) Explain how X is broken down by the enzyme. (4 marks) (c) Molecules Y is an inhibitor of the reaction between X and the enzyme. (d) X Explain how Y leads to the inhibition. (3 marks) Explain why heating may cause an enzyme to lose its activities. (4 marks) End Answer 8 Book 1 - Answer 1 Molecules of life The answers below are split in separate lines for the clarity of ideas. In the examination, candidate should present them in an essay form 1.1 Soak the soybeans overnight to soften it. 1 Grind with water to obtain an extract. 1 Test the extract with Albustix paper. Positive result: If protein is present, the reagents at the tip change from yellow to [blue-green / blue / green] 1 (1) Role of DNA There are about 20 kinds of amino acids. 1 1 These amino acids join with each other to form a polypeptide, which will become a protein with a specific conformation. 1 The type and sequence of amino acids in a particular polypeptide is determined by genetic codes, which are inherited from the parents and are carried by the DNA in the nucleus. A certain section of the DNA constitutes a gene. 1 Each gene has a specific base sequence and this sequence will direct the formation of a specific polypeptide with a specific amino acid sequence. 1 (Accept: Biuret test.) 1.2 Layout of the answer: 1. Having a special conformation Role of DNA => Amino acids with a specific sequence forming a polypeptide => coiling to form 3-dimentional shape. (The concept is that different arrangements of amino acids in a polypeptide would lead to different conformations.) 2. Different functions Enzymes and active sites. Antibodies for body defense. (Reject "formation of a specific protein" at this stage.) (2) Folding to a 3-dimentional shape Hydrogen bonds can be formed between the amino acids in a polypeptide. These bonds link up different parts of the polypeptide so that the polypeptide folds into a 3dimensional shape, so forming a protein. 1 Since a polypeptide has its specific amino acids sequence, the positions of the hydrogen bonds are also specific. This gives a specific conformation to the protein. 1 Haemoglobin for carrying oxygen. Proteins on cell membrane, receptors for neurotransmitters and hormones. Note: Don't include hormones because peptide or protein hormones are usually short peptide chains with no special conformation. Marks will be lost for including irrelevant materials. Maximum 4 marks for parts (1) and (2) 9 Answer For example, the cell membrane of the postsynaptic cell has receptors for the neurotransmitters released from the pre-synaptic cell. This allows nerve impulses to cross the synapse. (3) Different functions Each protein, with its specific conformation, can carry out a specific function that depends on the conformation. The following are some examples. Enzyme: Enzymes are biological catalysts that control the reactions in a human body, from cellular metabolic activities to the digestion of foods. Each enzyme has a location called active site, which has a special shape that is complementary to the shape of the substrate molecules. Reaction occurs when the substrate molecules have fitted into the active site to form an enzyme-substrate complex. Antibodies: Antibodies are a chief mechanism of body defence. When a pathogen with a special antigen has entered a human body, antibodies with a shape complementary to the antigen are produced. The antibodies will bind to the antigen and so making the pathogen inactive. Haemoglobin: A haemoglobin molecule consists of four polypeptide chains. There are sites which can bind with oxygen. At the lung, oxygen bind to haemoglobin, which then carries the oxygen to other parts of the body. Cell surface receptors: Some cells have protein receptors on the cell membrane. These protein receptors have special shapes that serve as a binding site for the molecules with a shape complementary to the binding site. 1 Another example is the receptors on the cell membrane of the target cells of insulin (or a hormone). These receptors have a special shape that enables them to act as a binding site for only insulin (or a particular hormone). So insulin has effects only on its target cells. 1 1 1 1 (Accept general description on hormones instead of insulin.) 1 Maximum 6 marks for part (3) 1 Marks on communication: Answers incoherent with many irrelevant materials. 0 mark 1 Answers incoherent but still can be made out by readers spending time on it. With some irrelevant materials. 1 mark Answers can be easily understood but still with some irrelevant materials. 2 marks 1 Answers logical and coherent. With no or negligible irrelevant materials. 3 marks Maximum for total final = 13 1 1.3 (a) (i) A: protein and [triglyceride / fat / oil / lipid] 1 1 (Both correct for one mark.) (ii) B: triglyceride / fat / oil / lipid 1 (iii) C: reducing sugar 1 (Reject sugar's name such as glucose.) 1 (b) Boil the foodstuff with acid, then neutralise with hydrogencarbonate. 1 10 Answer (No mark if neutralised.) the Heat the resulting Benedict's solution. solution is not General quality of drawing and title: Clear and large diagram, without shading. solution The appearance of a [red / brick-red / orange] precipitate indicates the presence of non-reducing sugar in the foodstuff. (c) Add iodine solution to the foodstuff. A blue black colour indicates the presence of starch. 1 A proper title for the diagram. 1 The following parts correctly drawn and labelled: Phospholipid molecules line up as a layer. 1 1 (Reject "iodine" instead of "iodine solution". Reject "blue colour" instead of "blue black colour".) 2 ½ ½ Neat guide lines without crossing. with 1 Phospholipid bilayer with orientations of the molecules. correct 1 A transmembrane protein labelled as [carrier / channel / transmembrane] protein 1 A labelled glycoprotein shown on the surface 1 A cholesterol among the hydrophobic tail of the phospholipid molecules. 1 Cellular organisation 2.1 All that is required is a simple line drawing showing the important structures and without much touch up such as shading or too much dotting. For example: glycoprotein (or glycolipid) phospholipid molecule cholesterol carrier protein (or channel protein) Structures of a plasma membrane 2.2 (a) The alcohol in tube Y had a higher concentration 1 because the alcohol in tube Y had higher red colour intensity. 1 The alcohol dissolved the phospholipid of the membranes. The red pigment in the vacuole was released and dissolved in the alcohol. 1 The alcohol in tube Y had a higher concentration and so the membranes were dissolved faster. 1 The alcohol could also reach the deeper part of the beetroot cube faster. 1 In tube Y, more red pigment was released. 1 Maximum 5 Answer (b) In two hours time, all membranes in both cubes had been dissolved and so all pigments diffused and distributed evenly in the alcohol. 1 Sine the two cubes came from the same beetroot and had similar size, the concentrations of the red pigment in the two alcohols are similar. 1 2.3 (a) Because most life activities are carried out by the organelles and not just by a semi-fluid materials. 1 11 (ii) Protoplasm was once believed to be the material responsible for life. Later it is known that the organelles are responsible for life activities after scientists had identified the organelles under electron microscope and studied their activities. (iii) Most organelle cannot be seen under light microscope and so scientists know the existence of organelles only after the invention of electron microscope. 1 1 (Do not accept the general description on the advantage of electron microscope. The answer must be focused on the identification of organelles.) (Accept any idea of the complexity of the cell that is more than just protoplasm.) (b) Because an electron beam has a shorter wavelength than a light beam, and so the electron microscopes can have a higher resolution than the light microscopes even both have the same magnification. 1 4 Enzymes 1 4.1 (a) A circle around the active site 1 For example: (c) This type of question requires a candidate just to select from the provided information the material that fits the statement on the left column and then write a comment on it. No other materials are required unless specified. And don't just copy the question as the answer. (i) Scientists believed that the protoplasm was the basis of life because they found that the protoplasm could show all life activities. (Or: Scientists isolated organelles and found they showed life activities. So life depends on these organelles.) (b) The shape of X is complementary to the shape of the active site. 1 1 (Reject "[same / similar] shape as the active site".) X fits into the active site, 1 forming an enzyme-substrate complex, 1 in which the activation energy is lowered. 1 12 Answer After the reaction, the products no long fit the active site and they detach from the active site. 1 Maximum 4 (c) Y can fit into the active site. 1 This blocks the active site and so X cannot fit into the active site. 1 No enzyme-substrate complex can be formed. 1 (d) Heating increases the kinetic energy of the [molecules / atoms in the molecule]. 1 (Or: increases the vibrations of the [molecules / atoms in the molecule].) This causes the breaking of the hydrogen bonds and ionic bonds in the enzyme molecule, which then leads to a change in the [tertiary structure / configuration] of the enzyme. 1 1 (or leads to denaturation). The shape of the active site is changed. 1 The substrate cannot fit into the active site. / Enzyme-substrate complex cannot be formed. 1 Maximum 4 End