YALE NEUROLOGY RESIDENT SURVIVAL GUIDE 2011-2012 Contributors: Mary Bailey, MD Pooia Fattahi, MD Ben Keung, MD Imanuel Lerman, MD Laura Ment, MD Karin Nystrom, APRN Imran Quraishi, MD Katherine Ruzhansky, MD Anna Sorokin, MD Editors: Nicholas A. Blondin, MD Kumar Narayanan MD PhD Kamil Detyniecki, MD Christopher Gottschalk, MD Kim Robeson, MD David Greer, MD 1 Table of Contents Emergencies IV tPA administration ...................................................................................................... 3 Intracranial Hemorrhage s/p IV tPA ................................................................................. 5 Acute Management of Intracranial Hemorrhage .............................................................. 6 Management of Acute Elevations in ICP ......................................................................... 8 Mannitol Protocol for elevated ICP .................................................................................. 9 Status Epilepticus (adult) ............................................................................................... 10 Guillain Barré Syndrome ............................................................................................... 11 Myasthenic Crisis ......................................................................................................... 12 Chill Alert ...................................................................................................................... 13 Ward Issues Typical Day ................................................................................................................... 14 Transfers, Computer Systems ........................................................................................ 15 Dictation Instructions Dial 688-6406 ............................................................................. 16 Discharging a patient ..................................................................................................... 17 Lumbar Puncture ........................................................................................................... 18 Common Consults Ischemic Stroke ............................................................................................................. 19 Young Stroke ................................................................................................................. 20 Seizure .......................................................................................................................... 21 Altered Mental Status .................................................................................................... 22 Coma Exam ................................................................................................................... 23 Headache ...................................................................................................................... 23 Spinal Cord .................................................................................................................... 25 Multiple Sclerosis Exacerbation .................................................................................... 26 Dizziness ....................................................................................................................... 27 Pediatric Seizure Phone Call .......................................................................................... 30 Useful Information Pediatric Anticonvulsants .............................................................................................. 31 Common Anticonvulsants .............................................................................................. 32 Muscles, Nerves and Roots ............................................................................................ 33 Computer Remote Access .............................................................................................. 34 Phone Numbers.............................................................................................................. 35 2 Emergencies: IV tPA administration IV tPA Administration Review all exclusion criteria and confirm patient is eligible Review benefits and risks with the patient and family and provide IV tPA information sheet Obtain informed consent Ensure 2 peripheral IV lines or more access Call the pharmacy (688-1111) with patient information and instructions to mix and immediately deliver drug to patient location Make sure pump available to deliver drug Dose: 0.9 mg/kg body weight (maximum 90 mg) 10% of dose given as a bolus – over one minute Remainder of dose to be infused over 60 minutes (via pump) When infusion is complete, attach a NS bag to tPA IV tubing & deliver remaining drug in tubing to administer full dose Management of Anaphylaxis If stridor, oropharyngeal swelling, urticaria develop, immediately discontinue tPA infusion. Administer IV methylprednisolone 125 mg, IV diphenhydramine 50 mg, IV famotidine 20 mg, Consider early elective intubation if significant stridor or oropharyngeal swelling. Early ENT notification if cricothyrotomy may be needed Consider medicine consultation if no improvement Consider CT scan to exclude retropharyngeal hematoma if suspected Post IV tPA Administration Admit to NICU NPO until patient is screened for dysphagia Continue cardiac monitoring Neurochecks q 15 mins x 2 hours, then q 30 mins x 6 hours, then q 1 hour x 16 hours Rotate blood pressure cuff to avoid excessive bruising No anticoagulants or antiplatelet agents for 24 hours DVT prophylaxis Repeat head CT, labs, U/A and guaiac stools at 24 hours post infusion from YNHH Stroke Service Policy “Administration of IV t-PA for Acute Ischemic Stroke” 3 4 Emergencies: Intracranial Hemorrhage s/p IV tPA Administration of blood products will be at the discretion of the stroke attending After administration of IV t-PA, monitor for following concerning symptoms: Worsening or new deficits, worsening GCS or NIHSS or decreased level of consciousness Nausea, vomiting, sudden severe headache Seizure Sudden elevated blood pressure and/or bradycardia If intracranial hemorrhage is presumed Immediately discontinue t-PA infusion Obtain STAT head CT scan Re-assess the patient’s neurologic status – perform and document NIHSS Draw labs: type and screen to blood bank ONLY if patient is new to YNHH - - Immediately, upon documentation of intracranial hemorrhage by CT scan (preliminary read is acceptable): Call blood bank (688-2443) Order 10 units (volume approximately 50 mL) of cryoprecipitate If patient received an antiplatelet agent during the prior 2 weeks, or if an antiplatelet use during that interval is unknown, also order 8-10 units platelets (volume approximately 400-500 ml) Consider pre-medication 30 mins prior to transfusion (acetaminophen 650 mg PO or PR and/or diphenhydramine 25 mg IV) - Cryoprecipitate will be administered IV (using a 22 gauge) over 15 mins Platelets will be administered IV (using a 22 gauge) over 30-60 mins If the patient exhibits signs of transfusion reaction, immediately stop platelet infusion - STAT Neurosurgery consult (370-4492) Consider Hematology consult (688-2443) Discuss medical versus surgical therapy - Repeat lab draw (PT, PTT, INR, fibrinogen) after administration of cryoprecipitate If PT/PTT is elevated, consult heme for further recommendations If fibrinogen < 150 mg/dl, order and administer additional 10 units cryoprecipitate Consider serial CT scans to assess size and change of hemorrhage - 5 Emergencies: Acute Management of Intracranial Hemorrhage Control BP: Goal SBP 100-140 Labetalol 10-20mg IV q1h prn OR Nicardipine drip (5 mg/hr increased by 2.5 mg/hr q15 minutes to max 15 mg/hr) Arterial line placement while patient is in ED Check BP q5mins x 1 hr then q15mins x 2hrs then q30mins If patient is on Coumadin: INR goal <1.4: o STAT FFP: 10-20 ml/kg or 4-6 Units, if has CHF, give Lasix after infusion – send runner to blood bank o Vitamin K 10mg IV x 1 (slow push over 5 minutes) (takes 6 hrs to normalize INR), check PT/INR q6hrs If patient is on Heparin gtt: o Protamine 1mg/100 Units if received heparin in last 3 hours. o Check PTT q1hr x 4 hrs then q4hrs If patient is on Enoxaparin: o Protamine 1mg per 1mg of enoxaparin o Recheck PTT in 2-4 hrs; if still elevated consider giving additional 0.5mg of Protamine If patient received IV tPA < 24 hrs ago then give (see reversal of t-PA protocol): Cryoprecipitate and Platelets If patient is on Direct Thrombin Inhibitors (Argatroban, Lepirudin, Bivalirudin, Dabigatran): There is no specific antidote for these drugs at this time Von Willebrand syndrome: Treat with 0.3 mcg/kg DDAVP over 30 min If platelets are < 100k, transfuse platelets No need for prophylactic AEDs. No indication for steroids. Osmotic therapy only if significant edema is present and patient exam compromised. No data for platelet transfusion if patient was on ASA, Plavix or NSAIDs (but is often given by neurosurgery). May restart antiplatelets in one week after ICH DVT/PE prophylaxis: on admission place patient on SCDs. Patients with DVT/PE may need to get IVC filter. May start prophylaxis SQ Heparin/LMWH 48 hours post-ICH Consult neurosurgery (370 4492) if warranted Repeat Head CT in 6 hrs or STAT PRN change in neurological exam Neurochecks q1hrs, HOB 30 degrees Adopted from http://www2.massgeneral.org/stopstroke/protocolAdultHemorrhage.aspx 6 ICH Volume estimation = (A x B x C) / 2 A = longest diameter B = diameter perpendicular to A C = number of slices multiplied by slice thickness in cm 7 Emergencies: Management of Acute Elevations in ICP ETIOLOGY: variety of causes (tumor, malignancy, stroke, encephalitis, hemorrhage, hydrocephalus, trauma, global anoxic brain injury) SIGNS AND SYMPTOMS: headache, nausea / vomiting, somnolence or coma, hiccups, yawning, focal deficits especially brainstem findings, seizures, anisocoria, unreactive or blown pupil, posturing, abnormal breathing pattern, Cushing’s triad [hypertension, bradycardia and irregular respirations] WORKUP: ABCs, clinical exam and STAT HEAD CT (wheel the patient yourself) MANAGEMENT (If high suspicion, may want to start treatment on your way to CT) ABCs: vital signs and cardiac monitoring, consider intubation HOB elevated at 30 degrees, head facing forward Consult neurosurgery (370 4492) for possible intervention Goal ICP < 20 mm Hg and cerebral perfusion pressure (CPP) > 60 (see below for equation) If herniation present: STAT mannitol 100 g and then proceed to mannitol protocol (see next page) OR hypertonic saline Hyperventilation: for goal pCO2 ~ 30 If ICP due to tumor: dexamethasone 10 mg IV x 1, then 4 mg q6hr For any patient with a mass lesion, stroke, tumor, hemorrhage, keep goal Na 140-145 (may need to go higher depending on what ICP does). Avoid free water in IVF such as D5W, ½ NS, D5 ½ NS, LR CPP = MAP – ICP MAP ≈ (2DBP+SBP)/3 8 Emergencies: Mannitol Protocol for elevated ICP For a patient with ICP monitoring: Mannitol 1 g/kg q6hr PRN ICP ≥ X, Hold for Osm Gap > 10 or Na > 160 or Serum Osm > 320 For a patient without ICP monitoring: Mannitol 1 g/kg q6hr, Hold for Osm Gap > 10 or Na > 160 or Serum Osm > 320 Check Na, BUN, Cr, Gluc, Osm q6hr, one hour before mannitol dosing ↓ Is Osm Gap >10 or Na > 160 or Serum Osm > 320? ↓ ↓ Yes No Hold Mannitol Administer next dose if indicated by ICP Equations: Osm Gap = measured Osm – calculated Osm Calculated Osm = 2(Na) + BUN/2.8 + Glu/18 + 10 Osm gap < 0 may be due to miscalculation or minor variation in lab values; mannitol may be given if calculation correct May order hypertonic saline in the presence of a gap Unexpected gaps may be caused by alcohol or propylene glycol carrier (lorazepam, diazepam, midazolam, pentobarb and phenobarb) Adapted from http://www2.massgeneral.org/stopstroke/osmalarGap.aspx 9 Emergencies: Status Epilepticus (adult) Interventions Initial Rapid Assessment: Airway, Breathing, Circulation Record Vital Signs, Monitor 02 saturation, EKG Establish IV access and have bloods sent: fingerstick, CBC, electrolytes, BUN/Cr, Ca/Mg/Phos, LFTs, AED levels, tox screen, ABG, HCG for women of reproductive age Thiamine 100 mg IV followed by 50% dextrose, 50 cc IV Lorazepam 0.1 mg/kg IV (<2 mg/min) OR Diazepam 0.25 mg/kg IV (<5 mg/min) Phenytoin 18-20 mg/kg IV (50 mg/min) or Fosphenytoin 20 mg/kg IV (150 mg/min), begin concurrently with benzodiazepine and monitor EKG, check BP q60 sec May use Valproic Acid 30 mg/kg IV (150 mg/min) or levetiracetam 50 mg/kg IV (100 mg/min, request *non-formulary*) as alternatives Perform follow up assessment including history, exam, check labs, STAT head CT, **STAT EEG** if still seizing or unresponsive, consider empiric antibiotics / LP if febrile / not known epileptic If still seizing, then: Additional phenytoin 7-10 mg/kg IV (<50 mg/min) or Fosphenytoin 10 mg/kg IV (150 mg/min), monitor EKG, check BP q60 sec Send repeat Phenytoin and free phenytoin level 20 min after load Intubate if not done previously If still seizing, then: Phenobarbital 20 mg/kg (75 mg/min) Establish arterial line for BP monitoring Initiate EEG monitoring If still seizing, options for next step include: Midazolam 0.2 mg/kg IV (loading dose, preferred if BP unstable), titrate dose (0.1-0.4 mg/kg/hr) to stop electrographic and clinical seizures. Use fluid or pressor support if needed. OR Pentobarbital 5mg/kg IV (loading dose) to obtain burst suppression on EEG, titrate dose (0.3-9mg/kg/hr, avg=4mg/kg/hr) to maintain burst suppression on EEG, use fluid to support BP if needed, add pressor only if fluid fails or not clinically advisable OR Propofol 1-2 mg/kg IV (loading dose), 2-10 mg/kg/hr maintenance drip to stop clinical and EEG seizures or maintain burst suppression on EEG Seizure activity 0 min 0-2 min 2-10 minutes 5-10 minutes 10-20 min 30-40 min 30-60 min 50-60 minutes STAT EEG: daytime – EEG lab 688-3109 / 688-2495; nighttime – attending approval 10 needed; notify technologist in CAVE 688-3269 Emergencies: Guillain Barré Syndrome - - - Admit to NICU q 1 hour neuro checks Place on Telemetry Watch for autonomic instability, avoid beta-blockers given risk of complete heart block Address Code Status while in ED, may need intubation Check NIF (Negative Inspiratory Force) and FVC q2hrs x 12hrs then q4hrs. Intubate if NIF < 20 or FVC < 15cc/kg (or 1 liter) or rapid downward trend Do not go by the O2 sat or ABGs for need for intubation as these patients will become hypercarbic before hypoxic. Call RRT at the first sign of respiratory distress Lumbar Puncture (look for albumino-cytological dissociation) Check HIV, CMV, Hepatitis panel, Campylobacter in stool DVT prophylaxis including SCDs EMG/NCS: absence of ‘F’ waves, conduction block, temporal dispersion May need Plasmapheresis. Consult IR for placement of the line and consult Lab Medicine for initiation of Plasmapheresis May need IVIg 0.4gr/kg/day x 5 days. Check IgA level prior to administration of IVIg as it may cause anaphylaxis in patients with IgA deficiency. Give Acetaminophen and Benadryl prior to each IVIg to decrease HA’s FEN: swallow eval, aspiration risk 11 Emergencies: Myasthenic Crisis - - - Admit to NICU q 1 hour neuro checks Place on Telemetry Address Code Status while in ED, may need intubation Check NIF (Negative Inspiratory Force) and FVC q2hrs x 12 hrs then q4hrs. Intubate if NIF < 20 or FVC < 15cc/kg (or 1 liter) or rapid downward trend Do not look at the O2 sat or ABGs as these patients will become hypercarbic before hypoxic. Call RRT at the first sign of respiratory distress Rule out infection with panculture May need Plasmapheresis. Consult IR for placement of the line and consult Lab Medicine for initiation of Plasmapheresis May need IVIg 2gr/kg over 2-5 days. Check IgA level prior to administration of IVIg as it may cause anaphylaxis in patients with IgA deficiency. Give Acetaminophen and Benadryl prior to each IVIg to decrease HA’s Immunomodulatory treatment: o Steroids: may acutely worsen weakness, monitor closely, methylprednisolone 60mg IV daily o If steroid ineffective or contraindicated: azathioprine, mycophenolate mofetil, or cyclosporine Cholinergics: do not give during crisis. FEN: swallow eval, aspiration risk EMG/NCS: decremental response with repetitive stim Avoid: aminoglycosides, erythromycin, azithromycin, tetracyclines, ciprofloxacin, clindamycin, phenytoin, lithium, beta-blockers, procainamide, quinidine and magnesium 12 Emergencies: Chill Alert CHILL ALERT: called for patients who suffer cardiac arrest and meet a number of criteria to undergo cooling to decrease the degree of neurologic injury. Neurology is paged on the stroke alert pager (688-xxxx number tagged with 3333; NOT 688-3333, which is the pediatric emergency room) and should respond immediately. Protocol: Examine patient. Patient should be comatose, GCS < 8. Patients who are waking up are not likely to require hypothermia. When in doubt, call the oncall hypothermia attending Obtain non-contrast head CT if possible, r/o ICH Obtain emergent portable EEG # 1 during hypothermia (core temperature 32-34 degrees Celsius) during daytime, contact the EEG lab (688-3109 / 688-2495) at night needs approval by the on-call critical care EEG attending and communicated to the technologist in the CAVE (688-3269, pager 412-7557) Document in your note: date / time of initial arrest (if known) time to CPR date / time of Restoration Of Spontaneous Circulation (ROSC) date / time of arrival in the hospital date / time of your neurologic exam and whether patient is on sedating or neuromuscular blockade agents and whether they are intubated coma exam (please refer to coma exam under Common Consults section) In your assessment and plan, please include the Arctic Sun EEG Protocol (this can be found in the acronym expander template available in Sunrise. Go to Preferences ---> Acronym expansion ---> Import from other user ---> Curiale, Gioaccino ---> @arcticsun): Phase I (initiation of cooling), day 1: EEG (portable, to be done in ICU) Phase II (rewarming), day 2: EEG (portable) Phase II (rewarmed), day 3: EEG at temperature >36C normal core body temperature If non-convulsive status epilepticus is suspected, then please call neurology to obtain emergent portable EEG 13 Wards Issues: Typical Day 6:15-7:30 AM Please arrive no later than 6:15 AM. You may need to arrive earlier depending on your patient load. Every morning you will be assigned to new patients, so please factor in the time to repeat a patient history and full exam. Get sign out from the overnight resident first. If they are not in the resident’s room then they are probably seeing a consult. Page them (203 370 5298). Pre-round until 7:30 THINGS TO DO IN ADDITION TO CHECKING ON YOUR PTS if you know that a pt is to be discharged make sure all of their paperwork is done (see note on how to discharge patients) ask nightfloat if the patient’s primary care physician was called (if not this needs to be done prior to rounds begin – even if it is just leaving a message with the answering service) make sure MRI safety sheet has been done check on what time all pertinent studies are scheduled for and have this info available for rounds (TTE, Carotid US, MRI etc) 7:30 – 8:00 AM (Mon, Tues, Thurs, Fri) MORNING REPORT Please arrive on time Wednesday is Grand Rounds that begin at 8am and thus there is no AM report. 8:00 – 8:30 AM: Finish pre-rounding; Write ICU progress notes 8:30 – 11 AM ROUNDS Meet in NICU to begin rounds We will be doing walk rounds. Please make sure the patient’s nurse is present. You can get the nurse’s personal phone number from the BA or from the main patient board. Make sure you call all consults very early! 12:00 PM : Noon conference, refer to schedule. Lunch usually provided 1:00-5:30 PM: Finish the day’s work. LPs need to be done no later than 2pm ideally Update the sign out daily. Remove non-pertinent information and make sure family contact info and code status are clearly stated. Please put one line in on their most updated exam findings. Goal is to be ready to sign out to the inpatient night float resident at 5:30 pm. Patient discharge: make sure to have all documentation finished the day prior to anticipated discharge All priority dictations need to be done! For the weekend: On Fridays please put all daily labs orders for Saturday and Sunday and note on your sign out that this is done 14 Wards Issues: Transfers, Computer Systems Transfers: When accepting a transfer from another service, or transferring a patient to another service: 1) Make sure that the patient has been accepted by the senior resident and attending on accepting service. 2) Ensure that the transferring team has provided you with the following in writing regardless of how long the patient has been on their service: - Hospital course by organ system. If there are no pulmonary issues, for example, they must state “no active pulmonary issues.” - All medications administered and justification for doing such. If a beta blocker was d/c’d due to bradycardia, for example, this must be communicated to the accepting resident. - All Abx, days thereof, and the reason for using one antibiotic versus another must also be communicated. - All lines placed must be signed out with dates of placement. If a line was d/c and then replaced, the transferring teams needs to make us aware. - After the transferring team has completed their transfer note, they must give verbal sign out to the accepting resident. The same process is applicable to patients being transferred to other services from neurology. When accepting a transfer from an outside hospital, which is done through Yaccess, request the name and contact info of the transfering physician and obtain a faxed discharge summary in addition to getting a verbal sign out with all of the above, and request that the patient must be transferred with CDs of their neuroimaging; an imaging report is not enough. An attending needs to accept any patient transferred to the service. Computer Systems: there are multiple systems at Yale for which you need individual passwords; VA has one Sunrise Clinical Manager (SCM): inpatient Yale system containing majority of inpatient info Centricity / Logician: outpatient Yale system. Will contain clinic notes, and used for ordering outpatient studies, including if you want to order a test for after discharge. Will also contain inpatient imaging reports, EEG reports, labs and discharge summaries. Synapse: Imaging at Yale ED charts: scanned Yale ED paper charts; username and password are your SCM username VA system is CPRS; VistaWeb contains records from outside VAs 15 Wards Issues: Dictation Instructions Dial 688-6406 - enter your dictation ID number _________ followed by the # key - Enter work type followed by the # key 2 for Discharge summary 4 for Priority discharge summary (for patients being transferred to another facility) - when prompted, enter patient's medical record number followed by the # key TO DICTATE: Press 2 to begin dictation Press 2 to pause (soft tone is heard in pause mode) Press 2 again to resume dictating DISCHARGE SUMMARY MUST INCLUDE THE FOLLOWING: your name (spell it out) and ID number attending physician (spell it out) date of admission and date of discharge principle discharge diagnosis secondary diagnoses (list all PMH diagnoses) operations, if performed during hospitalization. Otherwise state “None” disposition (home, rehabilitation facility, other hospital, hospice, morgue) chief complaint / HPI PMH medications on admission Allergies Family History Social History Review of Systems (MUST contain at least 7 systems) physical exam on admission hospital course (may want to dictate by system) pertinent labs and imaging with dates physical exam on discharge if patient is being transferred to a facility, discharge plan, also by system follow up appointments "please CC this discharge summary to..." and list names and addresses / phone numbers for patient's follow up physicians including follow up neurologist, primary care physician and any pertinent specialists TO END DICTATION OR EXIT SYSTEM: State “this will end dictation. Thank you.” Press 5 and hang up TO EDIT: press 2 to stop, press 3 to play back, press 7 to rewind, press 4 to move to end of dictation 16 Wards Issues: Discharging a patient Yale: Discharges at Yale require a few necessary components. Once the patient is ready for discharge, the following need to be completed: 1) If the patient needs to go home with services, or is going to a facility, please talk to our care coordinator about this plan. In this case, the patients will need to have a priority discharge summary dictated and a W-10 filled out in Sunrise 2) Follow up appointments: most patients should be made appointments for follow up with neurology, and should also be instructed to follow up with PMD in 1-2 weeks as well as any relevant specialists. Please refer to phone numbers list for follow up clinics. 3) Discharge instructions: This is in a Sunrise template and at minimum should include follow up appointments made with contact info / clinic address, the medication reconciliation, and reasons to come to the ED (in the case of stroke or TIA, should include changes in speech, hearing, vision, balance, numbness, weakness, tingling, headache, mentation) 4) Medication reconciliation: please reconcile admitting and discharging medications (you may need to confirm home meds with patient's pharmacy) and perform the medication reconciliation including giving patient any new prescriptions 5) Performance measures: a separate document on the Sunrise template, needs to be done before you can put in a discharge order 6) Discharge summary (please refer to dictation sheet as all discharge summaries are dictated); indicate in dictation to cc patient’s summary to PMD and any follow up physicians 7) Discharge order WHVA: 1. Discharge note 2. Discharge Medication Reconciliation 3. Discharge Instructions (Instruction <Patient DC Instruction>) 4. Fill any new medications at the outpatient pharmacy 5. Discharge summary to be done in CPRS 6. Follow up appt with neurology (place consult for Neurology Clinics, call 3118) and primary care (call appropriate primary care clinic) 17 Procedures: Lumbar Puncture Materials: LP tray, chlorprep x 4 or iodine solution, extra lidocaine, gown and face mask, sterile gloves, extra container (urine cup) Before procedure: 1. 2. 3. 4. Check Head CT r/o intracranial mass lesion Check INR, must be < 1.5 Check Platelets, must be > 100 obtain informed consent and perform “time-out” prior to procedure After procedure: document procedure via SCM procedure note afterwards, check for intact leg strength and sensation, instruct patient to lay flat and administer IV fluids Urgent indication: Suspected CNS infection (with the exception of brain abscess or a parameningeal process). Do funduscopic examination and head CT first to rule out raised ICP. Suspected subarachnoid hemorrhage (SAH) in a patient with a negative CT scan Potential Contraindications: Possible raised intracranial pressure: rule out increased ICP by head CT Thrombocytopenia: if platelet is less than 100k then give platelets prior to LP Anticoagulation: if INR > 1.5, then give 4 units of FFP, once finished then proceed with LP Suspected spinal epidural abscess Normal CSF pressure is 6-20 cm H20; obese patients may have up to 25cm H20 Bring CSF to the Specimen Drop-Off, Park Street 4th Floor, back of the chemistry lab What to Order: NOTE that SCM will print the tube number on the label Tube 1: Cell count Tube 2: Protein, glucose, FTA-ABS, CSF lyme, Cryptococcus, fungal cx Tube 3: Viral studies, bacterial culture Tube 4: Cell count, IgG index, MBP, oligoclonal bands Extra Tube: Cytology (use specimen cup, ideally 10 cc, at least 5 cc Evaluate for malignant cells in CSF Bring to Pathology Drop Off, EP-2 across from back elevators Extra Tube: Flow Cytometry (use specimen cup, 5 cc) Evaluate for lymphoma in the CSF Bring to Flow Cytometry, Park Street 5th floor Extra Tube: Gene rearrangement analysis (use specimen cup, 10 cc) Evaluate for lymphoma in the CSF: IgH – B cell, TCR – T cell High false negative rate with < 50 nucleated cells in CSF Bring to Molecular, EP 2-631. DO NOT bring to Molecular on Park St 18 Common Consults: Ischemic Stroke Right or left handed? Onset sudden or gradual? Symptoms at onset and progression in time Symptoms fluctuating? Had these symptoms in the past? Time of onset? If not witnessed, then last seen normal? If awoke with symptoms, what time were they last awake with no symptoms? Associated symptoms: headache / neck pain, alteration of consciousness, abnormal movements Is the patient on antiplateles / anticoagulation? Stroke risk factors: HTN, HL, DM, CAD, smoker, illicit drug use, personal or family history of hypercoagulable states, cardiac arrhythmias, cardiomyopathy, history of migraines, prior stroke /TIA EXAM: full physical and neurologic exam paying attention to BP and fingerstick, cardiac and carotid exam, new or old focal deficits, perform and document NIHSS WORKUP in the ED: Non-contrast head CT, labs: PT/PTT/INR, CBC, BMP, urine: UA, urine tox, CXR, EKG, Consider CTA neck to Circle of Willis (COW) PLAN: Determine stroke mechanism. Can use stroke order set (type “stroke”). Admit to neurology; neurochecks, vital sign parameters Initiate antiplatelet agent MRI brain w/wo with MRA TTE with bubble study Carotid Doppler if no CTA obtained Telemetry AND 24-hour Holter monitor PT/OT AM labs: lipid panel, HgbA1c, ESR/CRP, TSH/T4, cardiac enzymes, homocysteine, fasting glucose May consider permissive hypertension if blood pressure dependent exam and flow limiting lesion seen on vascular imaging; hold antihypertensives and halve betablocker dose 3 oz bedside swallow eval Fingersticks QID-AC and RISS Neurosurgery consult if large hemispheric or posterior fossa infarct Bowel regimen DVT ppx: heparin/venodynes Code status 19 Common Consults: Young Stroke HISTORY: Regular ischemic stroke workup and additionally ask about: FH of hyper-coagulable states, early heart disease, connective tissue disease If female, on oral contraceptives? Smoker? EXAM: same as adult ischemic stroke, include Fundoscopic exam to eval for sinus thrombosis. WORKUP: In addition to the regular stroke w/u, you may check the following: Hypercoaguable State: 1. PT, PTT, thrombin time, fibrinogen 2. “Hypercoagulable panel:” Includes APC Resistance, Antithrombin III, Protein C, Protein S 3. Acquired hypercoaguable screening: Lupus anticoagulant screen (DRVVT) (order in SCM is Dilute Russell Venom Viper”) Anti-Cardiolipin antibody Anti Beta-2 glycoprotein-1 antibody Anti-phospholipid antibody (APLS) (order in SCM is “Lupus”) 4. Hemoglobin screen if African American or Mediterranean 5. Fasting homocysteine (If above 14, check folate, vitamin B12 and MTHFR 677T gene mutation) 6. Lipoprotein A 7. Prothrombin 20210 gene mutation 8. If suspect metabolic disorder, urine amino and organic acids and lactate and pyruvate Rheumatologic Disorders: 1. ESR, CRP 2. ANA, ENA, dsDNA, Rheumatoid Factor, ANCA 3. Antiphospholipid Antibody 4. C3 (total level), C4 (total level) 5. Cryoglobulins 6. Hepatitis Panel 7. HIV Imaging: 1. MRV or CTV brain 2. TTE with bubble study 3. TEE 4. Lower extremity Dopplers (including calves) 5. MRV of the pelvic veins (order MRA abdomen/pelvis w/ gad and specify venogram in comments) 6. CT chest/abdomen/pelvis to look for malignancy 20 Common Consults: Seizure HISTORY: New onset seizure or known epileptic? If known epileptic, goal is to determine AED regimen and compliance, seizure type/frequency and last seizure, epilepsy physician, any recent triggers (see below). Check AED levels and if low or they are non-compliant, re-load; if not, consider increasing AED dose. Ask about prior AEDs tried. If new onset seizures, obtain comprehensive first seizure history: RISK FACTORS: history of febrile seizures, family history of seizures, prenatal and perinatal complications, developmental delay, history of head trauma, history of CNS infection, history of CNS mass TRIGGERS LOWERING SEIZURE THRESHOLD: medications, antiepileptic noncompliance, infection, metabolic abnormalities, toxic ingestion, menses, stress, sleep deprivation, EtOH / benzo withdrawal, bright lights or loud noise CHARACTERISTICS: aura (visual, auditory, olfactory, epigastric rising sensation, psychic (déjà vu, derrealization, depersonalization, fear, anxiety), type of seizure (especially how its starts), eyes open or closed, lateral eye or head deviation, length of seizure, associated tongue bite or other injury, incontinence, presence of post-ictal confusion, post-ictal weakness. SUBTLE SEIZURE SIGNS: history of staring, automatisms, waking up incontinent or injured (tongue bite). myoclonic jerks. EXAM: full neurologic exam paying close attention to mental state, post-ictal paralysis or other focal deficits, subtle signs of ongoing seizures such as abnormal movements, head or eye deviation, eyelid twitching, pupillary abnormalities or hippus; also check for tongue bite / other injury, and check meningeal signs ED WORKUP: AED levels, non-contrast head CT, basic labs including electrolytes and CBC, infectious workup (UA, CXR), tox screen, LP if concern for meningitis PLAN: AED: load and then standing dose if warranted EEG: for new onset seizure if EEG done within 24-48 hrs has highest yield. Order sleep deprived if possible. MRI with and without contrast, seizure protocol if warranted seizure precautions ativan IV PRN seizure activity evaluate medication list to see if anything lowers seizure threshold code status no driving for ≥ 3 months per CT state law Refer to the “First Seizure Clinic.” Kathleen.wilson@yale.edu or 203-785-3582 and leave message with patient contact and demographics 21 Common Consults: Altered Mental Status HISTORY: Onset Any precipitating factor Baseline level of functioning (history of dementia?) Recent infectious symptoms (dysuria, diarrhea / vomiting, URI symptoms) Symptoms to suggest CNS infection (neck stiffness, headache, nausea) Access to toxic ingestion / illicit substances Associated focal deficits or abnormal movements EtOH history EXAM: full general exam with attention to signs of intoxication, dehydration and infection, neurologic exam including MMSE and paying close attention to level of consciousness, focus / concentration, focal neurologic deficits; also check and document meningeal signs, asterixis and look for subtle signs of seizure WORKUP: determined by above but typically includes Fingerstick, Chem-7, Ca/Mg/Phos, BUN/Cr, LFTs, ammonia level, TSH, RPR, B12 Tox screen and alcohol level Carefully review medication list for medications that can cause AMS UA / UCx, CXR Non-contrast head CT +/- LP if fever / white count of unknown source, meningeal signs / symptoms, concern for HSV limbic encephalitis EEG to r/o non-convulsive status and assess degree of encephalopathy PLAN: Determine and treat underlying cause, often multifactorial Can consider IV thiamine empirically if malnourished or EtOH history Supportive measures in acute delirium: reorienting (clocks, calendars), familiar staff / family if possible, encourage sleep-wake cycles, visual and hearing aids if visually / hearing impaired Differential of altered mental status: Drugs Endocrine, Electrolytes, Ethanol, Emotional, Eyes/Ears Low O2, Lack of drugs, Liver Infection Retention Intracranial (stroke/hemorrhage/mass), Ictal Uremia, Under-nutrition, Under-hydration Metabolic 22 Common Consults: Coma Exam 1. Determine if patient is on sedating or neuromuscular blockade agents and whether they are intubated 2. Check vital signs, determine respiratory rate and pattern. 3. General physical exam (R/o head trauma, bruit, murmur, rales, ascites, edema) 4. Neurologic exam: MENTAL STATUS: o spontaneous eye opening o obeys verbal command o verbal effort o eye opening to sounds CRANIAL NERVES: o spontaneous eye movements (conjugate or orienting), o blink to visual threat o pupillary responses o corneal responses o oculocephalic reflex o cold calorics o facial grimace to noxious o facial symmetry o cough and gag reflexes MOTOR: o tone, arm / leg strength o seizures or myoclonus seen o Positive Motor: follows commands, localizes pain, flexor posturing o Negative Motor: extensor posturing, no response SENSORY: o eye opening to pain o localizes / withdraws from pain in extremities and whether this is symmetric REFLEXES: o deep tendon reflexes o presence of Babinski's or triple flexion response Glasgow Coma Scale: Eyes Open Best Motor Response Best Verbal Response Spontaneous 4 Obeys verbal command 6 Oriented, conversant 5 To command 3 Localizes painful stimuli 5 Disoriented, conversant 4 To pain 2 Withdraws 4 Inappropriate words 3 No response 1 Flexion to noxious 3 Inappropriate sounds 2 Extension to noxious 2 No response 1 No response 1 Common Consults: Headache 23 HISTORY: New headache or personal history of headaches, and is this one different? Location ? Quality ? Severity ? Onset (sudden or gradual)? Preceding aura? Transient visual obscuration, especially with valsalva? Associated features (nausea / vomiting / photophobia / phonophobia / diplopia / tinnitis)? What and how much have they taken for the headaches? Worsening factors (e.g. laying down, standing up, straining)? Diurnal pattern (e.g. worse in the morning)? OCP or Vitamin A / retinoid use? Recent weight gain? Any patient recently postpartum or with systemic cancer, HIV, or taking immunosuppressive drugs should be assumed to have a secondary headache until proven otherwise If chronic headache syndrome, ask about family history of headaches and screen for lifestyle factors: caffeine use, sleep, hydration status, frequency of analgesic use, relation to menses, stress, relation to weather If new headache syndrome, screen for red flags: recent head or neck trauma, chiropractor visits, fevers or chills, recent travel or sick contacts, altered mental state, neck stiffness, focal neurologic or visual deficits If associated visual changes in an older person, screen for GCA: fever, weight loss, jaw claudication, scalp tenderness, proximal limb myalgias, constitutional symptoms EXAM: vitals including temp and blood pressure full neurologic exam including Fundoscopic and visual fields, nuchal rigidity, focal neurologic deficits including Horner’s syndrome, scalp tenderness WORKUP: ESR necessary if patient is older (corrected ESR = (age + 10 if female)/2) PLAN: should be dictated by patient’s history and physical If no red flags, can start treatment with: IV hydration Reglan 10 mg IV (can repeat q6h, benadryl/ativan to reverse akathisia) Toradol 30 mg IV (can repeat q6h, caution for renal disease) Magnesium sulfate 2 g IV Refractory: Depakote 1000 mg IV x 1, Solu-medrol 1 g IV x 1 If red flags present: further workup including LP, neuro-imaging, and ophtho consult may be warranted 24 Common Consults: Spinal Cord HISTORY: Timeline and pattern of weakness and numbness, leg heaviness or warmth, back pain, trauma history, bowel or bladder symptoms, sexual dysfunction, perianal or saddle anesthesia, recent infectious symptoms, baseline ambulatory status. EXAM: In addition to standard exam, check pinprick and vibration on both sides of spine to assess for spinal cord sensory level, palpate / percuss for paraspinal tenderness, rectal exam for perianal sensation and anal sphincter tone, palpate bladder, bulbocavernosus reflex (pull Foley or squeeze glans, S1-3), carefully assess muscle tone, skin exam for rash if you suspects an inflammatory disorder, pay attention to DTRs (triceps C6-7, biceps C5-6, brachioradialis C5-6, knee L2-4, ankle S1) and cutaneous reflexes (upper abdominal T8-10, lower abdominal T10-12, plantar L5-S1) as well as check Hoffman’s and Clonus DIFFERENTIAL: Herniated disc, myelitis, spinal tumor, AIDP (if reflexes are lost), neuropathy, neurosarcoidosis, syringomyelia. CORD SYNDROMES: Brown-Sequard: Hemisection leading to ipsilateral dorsal column signs, contralateral spinothalamic signs, usually spared bladder function. Central cord: Segmental pain and temperature loss, segmental DTRs lost, segmental weakness/atrophy, UMN signs below the lesion, urinary urgency Extrinsic compression: Segmental symptoms indicate nerve root involvement, long tract findings (UMN signs, numbness, weakness, urinary urgency) indicate cord involvement. Pain and temperature loss begins sacrally. Spondylotic myelopathy: From disc disease or osteophytes, begin with segmental findings such as dropped reflexes at the level of the lesion and spastic weakness with hyperreflexia below the lesion, sensory findings usually come later. Conus medullaris: Sudden, bilateral, symmetric, spastic distal lower extremity weakness, loss of ankle jerks, low back pain, perianal numbness, early onset of urinary retention and overflow incontinence, impotence. Cauda equina: Flaccid lower extremity weakness, urinary retention late in the disease, decreased anal tone, occasional sexual dysfunction, saddle anesthesia, loss of knee and ankle reflexes, severe radicular pain, presentation may be asymmetric and gradual. CORD TUMORS: Extramedullary (outside cord) may be intradural (meningiomas and schwannomas) or extradural (metastatic tumors from breasts, lungs, prostate, leukemia, or lymphomas). Intramedullary are rare and usually gliomas (astrocytomas or ependymomas), in children usually lowgrade astrocytomas. WORKUP : 1. PVR with bladder scan or catheter for urinary retention 2. If you suspect acute cord compression, conus or cauda equina syndrome – this is a surgical emergency! Give dexamethasone 10 mg IV x 1, call spine service immediately (alternates between trauma and neurosurgery) for decompression, get STAT imaging 3. MRI spine w/wo, choose appropriate level; include diffusion if you suspect ischemia 4. Based on above, consider: Brain MRI for MS plaques; serum RPR, copper, B12, NMO Ab, ACE, ESR, ANA, Lyme, HIV, HTLV-1, Mycoplasma, hep panel; CSF for basic studies and AFB / TB cx, crypto ag, fungal stain/cx, viral PCR, Lyme, VZV, EBV, CMV, enterovirus, ACE, HHV-6/7, WNV 25 Common Consults: Multiple Sclerosis Exacerbation HISTORY: Symptoms (onset, duration, progression)? If suspected MS, other neurologic symptoms they may have had in the past which resolved? Recent signs of infection (fever, chills, URI symptoms, dysuria)? If known MS, have they ever had these exact symptoms before? This may suggest recrudescence due to systemic issue If known MS, MS history: when and how they were diagnosed type of MS (RRMS, PPMS, SPMS, NMO, etc.) what MS medication are they on and compliance last exacerbation, last round of steroids baseline deficits or character of their past flares EXAM: Vitals, full physical looking for signs of infection and full neurologic exam and specifically looking for APD / optic nerve pallor, INO, Lhermitte’s sign, spasticity / hyper-reflexia ED WORKUP: obtain UA / Ucx, CXR, basic labs PLAN: If suspected exacerbation: admit to neurology may need to consider changing or starting a disease modifying agent (discuss on rounds with attending) Make sure to call there neurologist if they are private consider steroids (solumedrol 1gram IV daily x 5 days) or IVIG if starting steroids, also start on PPI / H2 blocker and insulin sliding scale MRI with and without contrast of pertinent areas (brain, spine) PT/OT If suspected new diagnosis: Full differential needs to be considered and ruled out, possible further testing includes MRI brain and spine w/wo, ACE, Lyme, anti-NMO, RPR/VDRL, vasculitic and autoimmune panel, CSF for basic studies and oligoclonal bands, myelin basic protein, IgG index, Lyme, ACE 26 Common Consults: Dizziness HISTORY: Onset? Description of symptoms (lightheadedness, room spinning, walking on a boat) Severity Duration (brief episodes, long episodes, or constant) Worse with head turning or getting up? Nausea or vomiting? Headache or neck pain? Chest pain or palpitations? Recent head or neck trauma or neck manipulations? Associated ear pain, URI symptoms, aural fullness, tinnitus? Hydration status? Able to walk? Feel off balance or pulled to one side? Associated neurologic deficits, especially ataxia and brainstem symptoms (diplopia or other visual changes, tongue heaviness, taste changes, changes in voice, trouble chewing or swallowing EXAM: orthostatics if indicated, physical exam including otoscopic exam, full neurologic exam including detailed brainstem exam (include taste, LT and PP sensation of face, gag, tongue and uvula deviation, skew deviation of eyes), nystagmus (direction, extinguishing or not), head impulse test, Dix-Hallpike test, as well as cerebellar testing and gait exam WORKUP: to be dictated as above If there are red flags or you cannot rule out central etiology, obtain neuro-imaging such as non-contrast head CT, CTA neck up to circle of Willis, and admission to rule out posterior circulation stroke. Following admission, obtain MRI to rule-out stroke. If no red flags and symptoms suggest BPPV or other benign etiology: IV fluids Meclizine (25-100 mg/day in divided doses) or Valium (5-10 mg q3-4 hr PRN) Antiemetic (raglan or zofran) Teach Epley maneuver and give them a handout or PT for vestibular rehab 27 EPLEY Maneuver for BPPV - Right 28 EPLEY Maneuver for BPPV - Left 29 Common Consults: Pediatric Seizure Phone Call 1. Look up patient info Does patient have epilepsy? Most recent EEG? Most recent neuro-imaging? Med list Most recent note 2. Call parent to get history is patient sick or having a fever? any recent sleep problem, dehydration, or other provoking factor? what meds is patient on? when did patient get most recent drug levels checked? what is the pt's current weight? Tell parent you need to discuss case with a colleague, and that you will call them back with recommendations 3. Call senior resident, discuss case 4. Develop action plan: Does patient need to come to ED? (usually not) Check levels soon Increase AED dose for weight (as most kids gain weight) Consider another EEG or MRI Follow-up appointment 5. Call back parent Give them recommendations Tell them that pediatric neuro office is closed, but they will be contacted with an upcoming appt on the next business day 6. REMEMBER TO CALL Gerry at the pedi neuro office at 785-5708, ext 6, or Sheryl at 737-3654, to make the follow-up appointment. 7. Route note to appropriate pediatric neurology attending for review 30 Information: Pediatric Anticonvulsants Anticonvulsant Load Maintenance Level (mg/kg) (mg/kg/d) (ug/ml) Carbamazepine 15 – 20 6 – 12* Ethosuximide 15 – 30 40 – 100* 5 – 15** Lamotrigine Levetiracetam 4 – 16* 20 - 40 10 – 30 Oxcarbazepine Phenobarbital 15 - 20 5 15 – 30 Phenytoin 18 - 20 5 10 – 20 Topiramate 10 – 30 Valproic acid 15 – 30 Zonisamide 4–8 50 – 150* 10 – 40 * check trough levels ** if child on VPA, maintenance 1 – 5 mg/kg/d 31 Information: Common Anticonvulsants Medication Carbamazepine (CBZ) Side Effects Diplopia, blurred vision, lethargy, liver failure, SIADH, aplastic anemia Interaction PHT, PB, VPA – decrease levels Diltiazem, verapamil, cephalosporins, antifungals – increase levels None Gabapentin (GPN) Levetiracetam (LEV) Lamotrigine (LMG or LTG) Lethargy, ataxia, weight gain Lethargy, dizziness, depression, psychosis Insomnia, rash (severe) Oxcarbazepine (OXC) Hyponatremia, nausea, rash Phenobarbital (PB) Lethargy, sedation, depression VPA Phenytoin (PHT or DPH) Nausea/vomiting, dizziness, sedation, ataxia, gingival hyperplasia, liver failure, osteoporosis CBZ, PB – decrease levels None PHT, PB, OCPs – decrease levels VPA – increase levels CBZ, PB, PHT, VPA, verapamil – decrease levels VPA – increase levels Decrease OCP effectiveness Topiramate (TOP or TPM) Valproic Acid (VPA) Zonisamide (ZNS) Cognitive impairment, dizziness, metabolic acidosis, kidney stones, hypohidrosis PHT, CBZ, VPA – decrease levels Weight gain, hepatotoxicity, hyperammonemia, tremor, rash PHT, PB, TOP, CBZ – decrease levels Sedation, rash, kidney stones, hypohidrosis PHT, CBZ, PB – decrease levels Decrease OCP effectiveness Elavil – increase levels 32 Information: Muscles, Nerves and Roots Muscle Action Nerve Root Deltoid abduction & elevation of arm axillary C5, C6 Biceps flexion & supination of forearm musculocutaneous C5, C6 Brachialis flexion of elbow musculocutaneous C5, C6 Triceps extension of forearm radial C6-8 Brachioradialis flex. of elbow, forearm mid position radial C5, C6 Ext. Carpi Radialis wrist extension & radial deviation radial C6, C7 Abd. Poll. Brev. abduction of thumb median C7, C8 Pronator teres pronation of forearm median C6, C7 Flexor Carpi Radialis wrist flexion & radial deviation median C6, C7 Palmaris longus median C7-T1 Opponens Pollicis draws thumb forward and medially median C8, T Ext. Dig. Comm. extension of fingers posterior interosseous C7, C8 Ext. Carpi Ulnaris wrist extension & ulnar deviation posterior interosseous C7, C8 First Dors. Inter. abduction & adduction of fingers ulnar C8, T1 Flexor Carpi Ulnaris wrist flexion & ulnar deviation ulnar C7-T1 Abd. Digiti Minimi abduction of 5th digit ulnar C8, T1 Teres minor external rotation of arm axillary C5, C6 Supraspinatus abduction arm suprascapular C5, C6 Infraspinatus external rotation of flexed arm suprascapular C5, C6 Levator scapulae dorsal scapular C4, C5 Rhomboideus elevation & retraction of scapula dorsal scapular C5 Teres major internal rotation, add., & extension subscapular C5-C7 Serratus anterior arm rotation of scapula, abduction long thoracic C5-C7 Pectoralis major arm adduction & internal rotation anterior thoracic C5-C8 Pectoralis minor anterior thoracic C6-C8 Latissimus dorsi arm adduction, int. rotation & ext. thhoracodorsal C6-C8 Tibialis Anterior dorsiflexion & inversion of foot deep peroneal L4, L5 Ext. Digit. Brevis extension of toes deep peroneal L5, S1 Ext. Hallucis Longus extension of great toe deep peroneal L5, S1 Gastrocnemius plantar flexion tibial S1, S2 Tibialis Posterior inversion and plantar flexion tibial L4, L5 Soleus plantar flexion tibial L5-S Flexor Hall. Longus flexion of great toe tibial L5-S2 Vastus medialis leg extension at knee femoral L2-4 Iliopsoas flexion of hip femoral L2, L3 Rectus Femoris knee extension & hip flexion femoral L2-4 Gracilis knee flexion, leg internal rotation obturator L2-4 Adductor Magnus adduction of the thigh obturator L2-4 Gluteus Medius abd. & int. rotation of thigh superior gluteal L4-S1 Gluteus Maximus extension of hip inferior gluteal L5-S2 Biceps Femoris hip extension, knee flexion Sciatic trunk, peron. div.L5-S2 33 Information: Computer Remote Access How to access the Yale desktop while at the VA: 1. Logon to the VA desktop 2. Go to My Computer > M:\ 3. Double click on "scan.rdp" found near the bottom of the file list, click "Connect" 4. Logon to the VA desktop 5. Double click the "mstsc" icon 6. In the Remote Desktop Connection box, enter VHACONTMS5, then click "connect" 7. Logon to the VA desktop 8. Start menu > Internet Explorer 9. Enter the web address https://cag.ynhhs.org 10. Logon to the Yale portal with your Synapse (Novell) username and password How to get Synapse at Home: 1. Go to Yale ITS Software Library - http://www.yale.edu/its/software/ 2. Enter netID and password, select operating system 3. Download synpase 4. Login as you would at YNHH How to get SCM and Yale Desktop at Home: 1. Download Citrix XenApp client (formerly Metaframe Server) onto home PC 2. Obtain remote access privileges: Contact ITS Helpdesk at 688-4357 for current application forms 34 Information: Phone Numbers YNHH 20 York St. 06510 8=688 5=785 7=737 Neurology Consult Pager 370 5298 RADIOLOGY MRI Inpt Scheduling 200-5142/5143 / 5144 / 5145 MRI Suite 200-5130 Neuroradiology fellow: reading rm 2003181 Pager days: 688-3175; nights: 688-6180 CT Inpt Scheduling 82749 / 85639 CT Outpt Scheduling 84572 / 82433 CT Scanner (for Stroke Code) 85952 CT ED 82749 CT 2nd floor 85639 ED/night/weekend reading Rm 86180 CTAngio 86215 Holter lab 8-4134 Ultrasound Scheduling 200-5600; 200-5684 Ultrasound Reading Rm 200-1923 ECHO Scheduling 81296 ECHO appt 7411 / 54629 ECHO read 89404 / 89228 / 89359 X-Ray Tech 83515 Nuclear Med 2005610 CXR Reading Rm Weekdays 86170 Portable Xray 86172 / 86170 Fluoro LP: phone 86215, fax 85319 Youngson: 737-2691; 370-1359 Angiogram 88441 /85127 IR 85358; IR consults: 370-0915 Film Library 86054 Ballroom 688-3363 Conscious Sedation 688-5608 CALLING A STROKE CODE go to www.myairmail.com username: Stroke1, password: Yale; pick Mastergroup1 and send your text page OR Send text page via myairmail to: 203 370 6660 CLINICS - NEUROLOGY Page Operator 83111 Stroke Phone 688-7111 NEUROPHYSIOLOGY EEG/EMG Scheduling 82495 EEG reading room 54380 EEG tech on-call pager 412-7557 Tamara (EEG tech) c: 782-9174 LABS Chemistry 82444 Heme 82434 Immuno 82440 Micro 82460 Virology 83524 / 81872 Cytology 55430 Flow cytometry 82437 Surg path 52788 Blood Bank 55406 ADD ONS: Fax to 688-8281 or 8-8569 NEUROLOGY UNITS 6-3 and 6-2 Neuro Consult Pager 370-5298 SP6-3 82342 NICU 6-2 82341 6-3 Fax 81322 Neuro Residents Rm 87524 / 87451 CAVE: 83269, 83976 Geoff (OT) 128-3076 EMERGENCY ROOM ED Bubble 82222 AB-Side 85213 C-Side 84713 Pediatric ED 83333 CIU (Psych ED) 8-1616 Pharmacy Amber- 688-9946; 128-4933 Pharm Inpt 81111 Stroke Pharm 82212 / 82213 / 82215 Pharm Nonformulary 766-8652 CONSULTS 35 General Neuro, Epilepsy, Movement, Headache, Neuromuscular – 800 Howard Ave, YPB LL; 785-4085 / 785-5783 Email (weekends/holidays) tanya.smith@yale.edu MS Clinic – 40 Temple st, 785-5684 Stroke Clinic – 800 Howard Ave, YPB LL; 737-1057, e-mail (weekends/holidays) at stroke1@email.med.yale.edu First Seizure Clinic – 800 Howard Ave, YPB LL; 785-3582 or kathleen.wilson@yale.edu Pediatric Neuro Clinic - 785-5708 or 7854081 Dr. Baehring Clinic – Smilow Cancer Center, 8th flr, contact 785-7284 Yale Health Plan, Dr. Machado, 432-0038 Hearing and Balance Center, Dr. Navaratnam, 800 Howard ave, YPB, 7852467 Yale Primary Care Clinic 85555, 82471 Hill Health Clinic 503-3698 / 3000 / 3010 Coumadin Clinic 85102; 766-1552 Ophtho Clinic 785-2020; 54629 Dr. Lesser-neurophtho New Haven 7892020 Dr. Lesser-neurophtho Waterbury 5979100 Dental Clinic 82464 Fair Haven Health 777-7411 Nathan Smith Clinic 8-5303 Neurosurgery Clinic 785-2802 PT/OT 8-6811 MISCELLANEOUS Sue Fanning (Gaylord) 203-741-3348 CT Public Health 860-509-8500 Interpreter Services 8-7523 Alternative Therapy 200-6129 Cindie Peterson 5-6054 LOCAL NEUROLOGISTS Neurosurg beeper 370-4492 General Surgery 128-2199 Med Consult 128-2330 Anesthesia 4444 Dermatology 2454 Speech/Language Heather 128-3377 Speech/Swallow Dr. Leder 128-3104 Gaylord- Dave Rosenblum 741-3348; 284-2400 ID consult 860-260-7101 Psych consult 52618; 860-340-4213 Diabetic Service 412-4559 PICC service 766-6507 IR PEG Consult 370-0915 IR PEG Scheduling 85127 Plasmapheresis 200-4707 MEDICAL RECORDS East Pavilion Ground 82231 / 82224 Dictation Line 86406 ADMISSION/BED ASSIGNMENT Admission 82221 Bed Assignment 85051 / 128-2712 Care Coordinators NICU- Pam 412-0747 FLOOR/HOSPITAL OFFICE NUMBERS Hospitalist 84748 Rehab 8-8 82175 9W 87993 Dialysis 8-2407 Hospitalist Coverage 766-7633 Hospitalist Admission 766-7416 36 Norman Werdiger office 624-7893 Door Codes: Res Room 4-3-1 Supply room 6-3: 1-2-4 WEST HAVEN VA HOSPITAL 932-5711 NEURO DEPT General Number 932-5711 Neuro VA Call Pager 784-1222 Neuro Residents Rm 2657 (code 4951*) Neuro Call Rm 2143 (code 4951*) Neuro Office (George Gregoire) 4724 Fax Neuro office 937-3464 Specialty Clinic/Debbie 3118 IR 2940 / 2941 6th Floor Conf. Rm. 2657 HOSPITAL/WARDS/ED EEG/Jean 2653 Admission: 3966 / 3967 Gloria (transfers) 2667 Nursing Supervisor 1006 Bed Mgr: 477-1581 Medicine Paging 203 688 6569 xxxx PT 2887 (inpt) / 2885 (outpt) ED 4777 Sue - Care Coordinator: 3626 Psych ED 4471 Psych consult 867-3291 / 1048 Psych Inpt Unit 4481 LABS Phlebotomy 2906 / 3925 Chem lab. 2929, 2931 Cytology 2972 Heme lab. 4476 Urinalysis 2926 Micro lab: 2917 / 2918 Door Codes 4E Supply room 6875* 4W Supply room 2931* MICU supply room (23) + (51) SDU Supply room 2351* Josh Hasbani o 562-8071 6-5 Call room: 4-2-5 CAVE: 1-5-3 RADIOLOGY Neuroradiology 7466 CT 4646 / 2948 / 4187 / 4188 MRI 2983 Inpt ECHO 2774 IR 2940 / 2941 / 5595 U/S 5444 / 5594 / 5595 MRI tech 7467 / 2983 MRI Copy 2939 Ash (neurorads) 477 4735 Nuc Med 4684 PET 4403 Bed Management (day) 477 1581 Pharm inpt : 4498 Pharm outpt : 4708, 7227 MICU 3976 / 3980 / 3979 SW 477-2567 Yale RadED 688-6180 4E : 4441 / 4442 4W : 4451 / 4452 SDU 3155 SDU charge nurse 1020 Surgery consult 1003 Cyto 2972 Blood Bank 2924 Add-ons 2931 Surg Path 2974 Printers Resident room: NEU6 4th floor work room: med 21 5th floor work room: med 22 Clinic: AMB35 Labels: 4E: nur43 4W: nur44 SDU: nur29 37