姓名：李正達
科部：精神部
聯絡方式：
電話
Email
+886-2-28757027#298
ctli2@vghtpe.gov.tw
學歷：
1996-2003
國立陽明大學醫學系 MD
2009-2012
國立陽明大學腦科所 PHD
經歷：
2003-2005
2005-2007
2008-2010
2009.7-2010.6
2010.7-2010.10
2010.11-
玉里榮民醫院精神部 住院醫師
台北榮民總醫院精神部 住院醫師、總醫師
台北榮民總醫院精神部腦功能實驗室 臨床研究醫師
美國國家衛生研究院分子影像研究部 研究員
台北榮民總醫院社區復健精神科 臨床研究醫師
台北榮民總醫院精神部 主治醫師
2014 -
台北榮總庇護工場 副執行長
研究方向：
1.
2.
3.
4.
5.
腦功能影像
腦部刺激術(rTMS, TBS, tDCS)
難治型憂鬱症
躁鬱症
焦慮症
五年內研究著作：
1. Cheng-Ta Li, Yuan-Hwa Chou, Tung-Ping Su. Duloxetine in treating medically
unexplained pain and Raynaud’s phenomenon. J Neuropsychiatry and Clinical
Neurosciences. 2009 Fall; 21: 4 (SCI)
2. Ya-Mei Bai, Kun-Hsien Chou, Ching-Po Lin, Cheng-Ta Li, Kai-Chun Yang,
Yuan-Hwa Chou, Tung-Ping Su. White Matter Abnormalities in Schizophrenia
Patients with Tardive Dyskinsia : A Diffusion Tensor Image Study. Schizophrenia
Research. 2009; Mar 2. (SCI)
3. Cheng-Ta Li, Yuan-Hwa Chou, Cheng-Hung Yang, Ying-Chiao Lee, Tung-Ping
Su. Medically unexplained symptoms and somatoform disorders: clinical
challenges to psychiatrists? Journal of the Chinese Medical Associations. 2009
May; 72(5): 251-256 (SCI)
4. Cheng-Ta Li, Tung-Ping Su, Yuan-Hwa Chou, Ying-Chiao Lee, Mu-En Liu,
Hsiao-Lun Ku, Ian-Kai Shan, Ya-Mei Bai. Symptomatic Resolution Among
Chinese Patients With Schizophrenia and Associated Factors. Journal of the
Formosan Association. 2010;109 (5):378–388 (SCI)
5. Cheng-Ta Li, Ching-Po Lin, Kun-Hsien Chou, I-Yun Chen, Jen-Chuen Hsieh,
Chia-Liang Wu, Wei-Chen Lin, Tung-Ping Su. Structural and cognitive deficits in
remitting and non-remitting recurrent depression: A vox el-based morphometric
study. NeuroImage. 2010 (5): 347–356 (SCI, 2013 IF=6.132)
6. Cheng-Ta Li, Shyh-Jen Wang, Jussi Hirvonen, Jen-Chuen Hsieh, Ya-Mei Bai,
Chen-Jee Hong, Ying-Jay Liou, Tung-Ping Su. Antidepressant Mechanism of
Repetitive Transcranial Magnetic Stimulation in Medication-Resistant Depression
Using Cerebral Glucose Metabolism. Journal of Affective Disorders. 2010 July 1.
(SCI)
7. Lei Zhang, Tung-Ping Su, Kwang Choi, Maree J. Webster, Cheng-Ta Li, Ming-Yi
Chung, Ying-Sheue Chen, Ya-Mei Bai, Yuan-Hwa Chou, Jeffery L. Barker, James
E. Barrett, Xiao Xia Li, He Li, David M. P11 (S100A10) as a potential biomarker
of psychiatric patients at risk of suicide. Journal of Psychiatric Research. 2010
Sep 21. (SCI)
8. Lei Zhang1, Cheng-Ta Li1, Tung-Ping Su1, Kwang Choi, Maree J. Webster,
Ming-Yi Chung, Yu-Hua Hsu, Ying-Sheue Chen, Ya-Mei Bai, Yuan-Hwa Chou,
Jeffery L. Barker, James E. Barrett, Xiao Xia Li, He Li, David M. Benedek and
Robert Ursano. P11 expression and PET in bipolar disorders. Journal of Psychiatric
Research 2011 Nov; 45 (11): 1426-31 (SCI)
9. Cheng-Ta Li and Tung-Ping Su. Principle and efficacy of repetitive transcranial
magnetic stimulation on treatment-resistant depression. Clinical Medicine. 2011;
67(4): 256-261
10. Jussi Hirvonen, Robert S. Goodwin, Cheng-Ta Li, Garth E. Terry, Sami S.
Zoghbi, Cheryl Morse, Victor W. Pike, Nora D. Volkow, Marilyn A. Huestis,
Robert B. Innis. Reversible and regionally selective downregulation of brain
cannabinoid CB1 receptors in chronic daily cannabis smokers. Molecular
Psychiatry. 2011 July 12. (Accepted) (SCI, 2013 IF=14.897)
11. Pei-Chi Tu, Jen-Chuen Hsieh, Cheng-Ta Li, Ya-Mei Bai, Tung-Ping Su.
Cortico-striatal disconnection within the cingulo-opercular network in
schizophrenia revealed by intrinsic functional connectivity analysis: a resting fMRI
study. NeuroImage 2011 July (Accepted) (SCI)
12. Pei-Chi Tu, Li-Fen Chen, Jen-Chuen Hsieh,Cheng-Ta Li, Ya-Mei Bai, Tung-Ping
Su. Regional cortical thinning in patients with major depressive disorder: a
surface-based morphometry study. Psychiatry Research, NeuroImaging 2011 June
(Accepted) (SCI)
13. Cheng-Ta Li, Ya-Mei Bai Pei-Chi Tu, Ying-Chiao Lee, Yu-Lin Huang, Tzeng-Ji
Chen, Wen-Han Chang, Tung-Ping Su. Major Depressive Disorder and Stroke
Risks: a Population-Based, Matched Cohort Study. PLoS One, September 2012
(Accepted) (SCI)
14. Cheng-Ta Li, Ya-Mei Bai, Yu-Lin Huang, Ying-Sheue Chen, Tzeng-Ji Chen,
Ju-Yin Cheng, Tung-Ping Su. Antidepressant Resistance in Unipolar Depression
Predict Subsequent Bipolarity: The 1996-2007 National Health Insurance
Database in Taiwan. British Journal of Psychiatry. 2012 Jan; 200: 45-51 (SCI,
2013 IF=7.343)
15. Jussi Hirvonen, Paolo Zanotti-Fregonara, John Umhau, David T. George, Chul
Hyoung Lyoo, Cheng-Ta Li, Christina S. Hines, Hui Sun, Garth E. Terry, Cheryl
Morse, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis, Markus Heilig. Reduced
Cannabinoid CB 1 Receptor Binding in Alcohol Dependence Measured with
Positron Emission Tomography. Molecular Psychiatry. 2012 June 12. (Accepted)
(SCI, 2013 IF=14.897)
16. Cheng-Ta Li, Jen-Chuen Hsieh, Shyh-Jen Wang, Ya-Mei Bai, Bang-Hung Yang,
Wei-Chen Lin, Chen-Chia Lan, Tung-Ping Su. Differential relations between
limbic-thalamic-frontal metabolism and executive function in remitted patients
with bipolar I and bipolar II disorder. Bipolar Disorders, August, 2012 (accepted)
(SCI)
17. Mu-Hong Chen, Tung-Ping Su, Cheng-Ta Li, Wen-Han Chang, Tzeng-Ji Chen,
Ya-Mei Bai. Symptomatic Menopausal Transition Increases the Risk of
New-onset Depressive Disorder in Later Life: A Nationwide Prospective Cohort
Study in Taiwan. PLoS One, 2013;8(3):e59899 (SCI)
18. Ya-Mei Bai, Ching-Jui Chang, Shang-Ying Tsai, Yi-Chyan Chen, Mei-Chun
Hsiao, Cheng-Ta Li, Peichi Tu, Shang-Wen Chang, Winston W. Shen,
Tung-Ping Su. Taiwan consensus of pharmacological treatment for Bipolar
Disorder. Journal of the Chinese Medical Associations, 2013 Oct;76(10):547-56.
(SCI)
19. Cheng-Ta Li, Li-Fen Chen, Pei-Chi Tu, Shyh-Jen Wang, Mu-Hong Chen,
Tung-Ping Su*, Jen-Chuen Hsieh*. Impaired Prefronto-Thalamic Functional
Connectivity as a Key Feature of Treatment-Resistant Depression: a Combined
MEG, PET and rTMS Study. PLoS One, 2013 Aug 2;8(8):e70089. (SCI) (SCI,
2013 IF=3.534)
20. Pei-Chi Tu, Ying-Chiao Lee, Ying-Shiue Chen, Cheng-Ta Li, Tung-Ping Su.
Schizophrenia and the brain's control network: Aberrant within- and
between-network connectivity of the frontoparietal network in schizophrenia.
Schizophrenia Research, 2013 Jul;147(2-3):339-47. (SCI).
21. Hsiao-Lun Ku, Chia-Shu Lin, Hsiang-Tai Chao, Pei-Chi Tu, Cheng-Ta Li,
Chou-Ming Cheng, Tung-Ping Su, Ying-Chiao Lee*, Jen-Chuen Hsieh*. Brain
signature characterizing the body-brain-mind axis of transsexuals, PLoS One,
2013, June (Accepted) (SCI)
22. Yen-Ling Chen, Pei-Chi Tu, Ying-Chiao Lee, Ying-Shiue Chen, Cheng-Ta Li,
Tung-Ping Su. Resting-state fMRI mapping of cerebellar functional
dysconnections involving multiple large-scale networks in patients with
schizophrenia. Schizophr Res. 2013 Sep;149(1-3):26-34. (SCI)
23. Cheng-Ta Li*, Tung-Ping Su, Jen-Chuen Hsieh, Shung-Tai Ho. Efficacy and
Practical Issues of Repetitive Transcranial Magnetic Stimulation on Chronic
Medically Unexplained Symptoms of Pain: a Review. Acta Anaesthesiologica
Taiwanica, 2013 April (Accepted).
24. Teng S, Lu CF, Wang PS, Hung CI, Li CT, Tu PC, Su TP, Wu YT. Classification
of bipolar disorder using basal-ganglia-related functional connectivity in the
resting state. Conf Proc IEEE Eng Med Biol Soc. 2013 Jul;2013:1057-60.
25. Cheng-Ta Li1, Kun-Hsien Chou1, Tung-Ping Su, Chu-Chung Huang, Mu-Hong
Chen, Ya-Mei Bai, Ching-Po Lin. Gray Matter Abnormalities in Schizophrenia
Patients with Tardive Dyskinesia: A Magnetic Resonance Imaging Voxel-Based
Morphometry Study. PLoS One, 2013, June (Accepted).(SCI) (SCI, 2013
IF=3.534)
26. Chang PT, Cheng-Ta Li*. Mania induced by varenicline. F1000Research.
2013, 2:183 (corresponding author)
27. Yuan-Lin Liao, Po-Shan Wang, Chia-Feng Lu, Chih-I Hung, Cheng-Ta Li,
Ching-Po Lin, Jen-Chuen Hsieh, Tung-Ping Su*, Yu-Te Wu*. Cortical Shape and
Curvedness Analysis of Structural Deficits in Remitting and Non-Remitting
Depression. PLoS One. 2013 July 8 (7): e68625. (SCI)
28. Chia-Shu Lin, Hsiao-Lun Ku, Hsiang-Tai Chao, Pei-Chi Tu, Cheng-Ta Li,
Chou-Ming Cheng, Tung-Ping Su, Ying-Chiao Lee, Jen-Chuen Hsieh. Neural
Network of Body Representation Differs between Transsexuals and Cissexuals.
PLoS One. 2014 Jan 20;9(1):e85914. (SCI)
29. Cheng-Ta Li*, Ya-Mei Bai, Ying-Chiao Lee, Wei-Chung Mao, Mu-Hong Chen,
Pei-Chi Tu, Ying-Sheue Chen, Tzeng-Ji Chen, Wen-Hang Chang, Tung-Ping Su*.
High Dosage of Hypnotics Predicts Subsequent Sleep-Related Breathing
Disorders and Is Associated with Worse Outcomes for Depression: A Nationwide
Population-Based Cohort Study. Sleep, Apr 1;37(4):803-9. (SCI, 2013 IF=5.062)
30. Bai YM, Chiou WF, Su TP, Cheng-Ta Li, Chen MH. Pro-inflammatory cytokine
associated with somatic and pain symptoms in depression. J Affect Disord. 2014
Feb;155:28-34. (SCI)
31. Chen MH, Wei HT, Su TP, Cheng-Ta Li, Lin WC, Chang WH, Chen TJ, Bai YM.
Risk of depressive disorder among patients with herpes zoster: a nationwide
population-based prospective study. Psychosom Med. 2014 May;76(4):285-91.
(SCI)
32. Teng S, Lu CF, Wang PS, Cheng-Ta Li, Tu PC, Hung CI, Su TP, Wu YT. Altered
Resting-State Functional Connectivity of Striatal-Thalamic Circuit in Bipolar
Disorder. PLoS One. 2014 May 2;9(5):e96422. (SCI)
33. Chen MH, Wu YH, Su TP, Chen YS, Hsu JW, Huang KL, Cheng-Ta Li, Lin WC,
Chang WH, Chen TJ, Bai YM. Risk of epilepsy among patients with atopic
dermatitis: A nationwide longitudinal study. Epilepsia. 2014 Jun 10 (SCI)
34. Bai YM, Su TP, Tsai SJ, Wen-Fei C, Cheng-Ta Li, Pei-Chi T, Mu-Hong C.
Comparison of inflammatory cytokine levels among type I/type II and
manic/hypomanic/euthymic/depressive states of bipolar disorder. J Affect Disord.
2014 Sep;166:187-92. (SCI)
35. Cheng-Ta Li*, Mu-Hong Chen, Chi-Hung Juan, Hsiang-Hsuan Huang, Li-Fen
Chen, Jen-Chuen Hsieh, Pei-Chi Tu, Ya-Mei Bai, Shin-Jen Tsai, Ying-Chiao Lee,
and Tung-Ping Su*. Efficacy of Prefrontal Theta-Burst Stimulation in Refractory
Depression: A Randomized Sham-Controlled Study. Brain, 2014 Jul;137(Pt
7):2088-98. (SCI, 2013 IF=10.226)
36. Chen MH, Li Cheng-Ta, Tsai CF, Lin WC, Chang WH, Chen TJ, Pan TL, Su TP,
Bai YM. Risk of Dementia Among Patients With Asthma: A Nationwide
Longitudinal Study. J Am Med Dir Assoc. 2014 Jul 15. pii:
S1525-8610(14)00344-2. (SCI)
37. Chen MH, Chen YS, Hsu JW, Huang KL, Cheng-Ta Li, Lin WC, Chang WH,
Chen TJ, Su TP, Bai YM. Comorbidity of ADHD and subsequent bipolar disorder
among adolescents and young adults with major depression: a nationwide
longitudinal study. Bipolar Disorders, 2014 July (SCI)
38. Cheng-Ta Li*, Jen-Chuen Hsieh, Hsiang-Hsuan Huang, Mu-Hong Chen,
Chi-Hung Juan, Pei-Chi Tu, Ya-Mei Bai, Ying-Chiao Lee, Shyh-Jen Wang,
Chih-Ming Cheng, and Tung-Ping Su*. Cognition-Modulated Frontal Activity in
Prediction and Augmentation of Antidepressant Efficacy: A Randomized
Controlled Pilot Study. Cerebral Cortex, 2014 July (Accepted) (SCI, 2013 IF =
8.325)
39. Mu-Hong Chen, Cheng-Ta Li, Wei-Chen Lin, Hang-Tin Wei, Wen-Han Chang,
Tzeng-Ji Chen, Tai-Long Pan, Tung-Ping Su, Ya-Mei Bai. A predisposition for
allergies predicts subsequent hypertension, dyslipidemia, and diabetes mellitus
among patients with schizophrenia or bipolar disorder: A nationwide longitudinal
study. Schizophrenia Research, August 9, 2014.
40. Cheng-Ta Li, Tung-Ping Su*, Shyh-Jen Wang, Pei-Chi Tu, Jen-Chuen Hsieh*.
Decreased Prefrontal Glucose Metabolism as a Characteristic Feature of
Medication-Resistant Major Depression. British Journal of Psychiatry, 2015
Apr;206(4): 316-23 (SCI, 2013 IF = 7.343)
41. Ya-Mei Bai, Tung-Ping Su, Cheng-Ta Li, Shyh-Jen Tsai, Mu-Hong Chen,
Pei-Chi Tu, WF Chiou. Comparison of pro-inflammatory cytokines among
patients with bipolar disorder and unipolar depression and normal controls.
Bipolar Disord. 2015 May;17(3):269-77. (SCI)
42. Mu-Hong Chen#, Tai-Long Pan#, Cheng-Ta Li, Wei-Chen Lin, Ying-Sheue Chen,
Ying-Chiao Lee, Shih-Jen Tsai, Ju-Wei Hsu, Kai-Lin Huang, Chia-Fen Tsai,
Wen-Han Chang, Tzeng-Ji Chen, Tung-Ping Su, Ya-Mei Bai. Risk of Stroke
among Patients with Post-traumatic Stress Disorder: A Nationwide Longitudinal
Study. British Journal of Psychiatry, 2015 Apr;206(4):302-7. (SCI, 2013 IF =
7.343)
43. Cheng-Ta Li, Ya-Mei Bai, Jen-Chuen Hsieh, Hsin-Chen Lee, Bang-Hung Yang,
Mu-Hong Chen, Wei-Chen Lin, Chia-Fen Tsai, Pei-Chi Tu, Shyh-Jen Wang,
Tung-Ping Su. Peripheral and Central Glucose Utilizations Modulated by
Mitochondrial DNA 10398A in Bipolar Disorder. Psychoneuropharmacology,
2015 Feb (Accepted) (SCI, 2013 IF = 5.591)
44. Wen-Hsuan Lan, Ya-Mei Bai, Ju-Wei Hsu, Kai-Lin Huang, Tung-Ping Su,
Cheng-Ta Li, Albert C. Yang, Wei-Chen Lin, Wen-Han Chang, Tzeng-Ji Chen,
Shih-Jen Tsai, Mu-Hong Chen. Comorbidity of ADHD and suicide attempts
among adolescents and young adults with bipolar disorder: A nationwide
longitudinal study. Journal of Affective Disorders. 16 February 2015. (SCI,
IF=3.705)
45. Mu-Hong Chen, Cheng-Ta Li, Chia-Fen Tsai, Wei-Chen Lin, Wen-Han Chang,
Tzeng-Ji Chen, Tai-Long Pan, Tung-Ping Su, Ya-Mei Bai. Risk of Subsequent
Dementia Among Patients With Bipolar Disorder or Major Depression: A
Nationwide Longitudinal Study in Taiwan. J Am Med Dir Assoc. 2015 Feb 27.
pii: S1525-8610(15)00091-2. (SCI)
46. Chih-Ming Cheng, Ju-Wei Hsu, Kai-Lin Huang, Ya-Mei Bai, Tung-Ping Su,
Cheng-Ta Li, Albert C. Yang, Wen-Han Chang, Tzeng-Ji Chen, Shih-Jen Tsai,
Mu-Hong Chen. Risk of developing major depressive disorder and anxiety
disorders among adolescents and adults with atopic dermatitis: A nationwide
longitudinal study. Journal of Affective Disorders. Available online 5 March 2015.
(SCI, IF=3.705)
47. Cheng-Ta Li, Pei-Chi Tu, Jen-Chuen Hsieh, Hsin-Chen Lee, Ya-Mei Bai,
Chia-Fen Tsai, Shyh-Jen Wang, Ju-Wei Hsu, Kai-Lin Huang, Chen-Jee Hong,
Tung-Ping Su. Functional Dysconnection in the Prefrontal-Amygdala Circuitry in
Unaffected Siblings of Bipolar I Patients. Bipolar Disord. 2015 March 23
(Accepted) (SCI, IF=4.888)
48. Kuan-I Lee, Chin-Wei Chiang, Hui-Ching Lin, Jin-Feng Zhao, Cheng-Ta Li,
Song-Kun Shyue, Tzong-Shyuan Lee*. 2015. Maternal di-(2-ethylhexyl)
phthalate exposure deregulates blood pressure, adiposity, cholesterol metabolism
and social interaction in offspring. Archives of Toxicology. 2015 May 21. (SCI,
IF=5.078)
49. Chang MH, Hsu JW, Huang KL, Su TP, Bai YM, Li Cheng-Ta, Yang AC, Chang
WH, Chen TJ, Tsai SJ, Chen MH. Bidirectional association between depression
and fibromyalgia syndrome: A nationwide longitudinal study. J Pain. 2015 Jun 24.
(SCI, IF=4.220)
50. Tu PC, Lee YC, Chen YS, Hsu JW, Li Cheng-Ta, Su TP. Network-specific
cortico-thalamic dysconnection in schizophrenia revealed by intrinsic functional
connectivity analyses. Schizophr Res. 2015 Jun 13. (SCI, IF=4.430)
51. Li CT, Chen MH, Lin WC, Hong CJ, Yang BH, Liu RS, Tu PC, Su TP. The
effects of low-dose ketamine on the prefrontal cortex and amygdala in
treatment-resistant depression: A randomized controlled study. Hum Brain Mapp.
2016 Mar;37(3):1080-90. doi: 10.1002/hbm.23085. Epub 2016 Jan 29.
研究室成員：研究助理 張雯涵