Stability of Living Systems In its stable state, the human body is something like a wellbalanced mobile. To make a mobile hang evenly, you need to adjust the positions of the various objects so that they balance one another. All systems, including mobiles and the human body, need a way of maintaining equilibrium, or balance. When a system is in equilibrium, it is stable, and all its parts function smoothly. All organisms, whether they are humans, bacteria, or plants, must maintain internal equilibrium no matter what happens in their environment. The process by which the body’s internal environment is kept stable in spite of changes in the external environment is called homeostasis (hoh mee oh STAY sis). Homeostasis is at work when your body returns to its normal state after a startling or frightening event, such as a nightmare. The body’s resistance to disease also demonstrates homeostasis. You are surrounded by microorganisms that can make you sick, but you probably stay well most of the time. And when people become ill, they usually recover quickly. The immune system helps maintain homeostasis by killing diseasecausing organisms before they can do much harm. Negative Feedback Organisms have different ways of keeping internal stability. Negative feedback is one way in which living systems maintain internal equilibrium, or homeostasis. In negative feedback, a process is turned off by the condition it produces. To understand how negative feedback works, consider how a thermostat regulates the temperature in a room. When the room becomes cool, the thermostat “senses” the drop in temperature. The thermostat then turns the heater on. Later, when the heater has made the room warmer, the thermostat “senses” the rise in temperature and turns the heater off. Negative feedback is a cycle, as you can see in the diagram below. In humans, negative feedback helps regulate many functions. For example, negative feedback helps control the temperature of your body and the level of the sugar glucose in your blood. Negative Feedback The operation of a thermostat is an example of negative feedback. In negative feedback, a process, such as heating a room, is turned off by the condition it produces. Interpreting Diagrams What happens when a room becomes too cool? Keeping Body Temperature Constant Whether the air is cold or hot, the internal body temperature of birds and mammals is always about the same. A healthy human, for example, always has a temperature that is close to 37°C. Several processes keep body temperatures stable. Staying Cool Sweating is one thing that helps keep the human body at a stable temperature. When you become warm, you perspire. Perspiration, which is mostly water, then evaporates from your skin. Heat is needed to make water evaporate. That heat comes from your body. Therefore, the process of evaporation cools your body by removing heat. Some animals, such as dogs, get rid of excess heat by panting. When an animal pants, some of the saliva in its mouth evaporates. The evaporation of saliva, like the evaporation of perspiration, helps cool the body. Negative feedback is at work in both perspiration and panting. That is because excessive body heat leads to perspiration or panting, which in turn results in a reduction in body heat. Shivering While perspiration helps the body cool off, shivering helps keep it warm. If you become chilled, you shiver. When you shiver, muscles in your body contract involuntarily. These muscle contractions require energy, and the production of energy generates heat. Therefore, shivering has the effect of warming the body. This method of temperature regulation, like perspiration and panting, is an example of negative feedback. When the body becomes uncomfortably cool, shivering results. Then shivering makes the body warmer Maintaining Glucose Levels in the Blood The energy your body needs to function comes from the breakdown of the sugar glucose in chemical reactions inside your cells. Glucose comes from the food you eat. After glucose is absorbed by the digestive system, blood transports the glucose and delivers it to cells. The level of glucose in the blood is regulated by chemical reactions. The chemical reactions are controlled by hormones of the endocrine system. A hormone is a chemical produced by an endocrine gland that affects the activity of a tissue or organ. One hormone that helps regulate glucose levels is insulin, which is produced by an organ called the pancreas. When the level of glucose in the blood is high, the pancreas releases insulin. Insulin stimulates body cells to take up glucose from the blood. This lowers the level of glucose in the blood. Low levels of glucose in the blood, in turn, “turn off” the production of insulin. This is a negative feedback process because high levels of glucose eventually lead to the reduction of glucose levels in the blood. Maintaining Water Equilibrium in Plant Cells To maintain homeostasis, living things need some way of regulating the amount of water in their cells and tissues. Like all organisms, plants need to maintain water equilibrium in spite of changing conditions. Diffusion Many plants obtain water through roots. Water enters these plants through root cells. The cells in a plant’s roots, like all cells, are bound by a thin, flexible structure called the cell membrane. The cell membrane is selectively permeable—that is, some substances can pass through, while others cannot. Substances move back and forth through the cell membrane by a process called diffusion. In diffusion, molecules move from an area in which they are highly concentrated into one in which their concentration is lower. Diffusion Molecules move from an area of higher concentration to an area of lower concentration. (A) There is a lower concentration of molecules inside the cell than outside. (B) Molecules from the Water Equilibrium in Animals Animals, like plants, need to maintain water balance. When your body needs water, you become thirsty, and you drink fluids. This action enables your body to obtain the water it needs. Many animals have excretory systems that help maintain water balance in the body. Your kidneys, which are part of your excretory system, remove wastes produced by your cells. Another role of the kidneys is to adjust the amount of water in your blood. They do this by changing the concentration of water in the urine they produce. Suppose, for example, that you drink a lot of water—too much for your body to use right away. When that happens, the kidneys produce urine in which the concentration of water molecules is high. When the urine is eliminated from the body, the excess water is eliminated too. In contrast, on a hot day, you might lose a lot of water through perspiration. In that case, the urine that the kidneys produce will have relatively little water. This helps keep water inside the body, where it is needed