Karyotyping Activity
Go to:
Name _______________________
www.biology.arizona.edu
Click on karyotyping under human biology.
1. What causes a dark band on the chromosome?
2. What is a centromere?
Click on Patient Histories
Click COMPLETE PATIENT A’S KARYOTYPE
3. Summarize (tell the main ideas) about Patient A’s medical history.
4. Count the total chromosomes in the karyotype.
5. The last set of chromosomes is the sex chromosomes. If you have 2 large chromosomes, your patient is XX
(female); one large and one small chromosome indicates XY (male). What sex chromosomes does your patient
have?
6. Which set has an extra chromosome?
7. What diagnosis would you give this patient? What disease does this patient have?
Click COMPLETE PATIENT B’S KARYOTYPE
8. Summarize (tell the main ideas) about Patient B’s medical history.
9. Count the total chromosomes in the karyotype.
10. The last set of chromosomes is the sex chromosomes. If you have 2 large chromosomes, your patient is XX
(female); one large and one small chromosome indicates XY (male). What sex chromosomes does your patient
have?
11. Which set has an extra chromosome?
12. What diagnosis would you give this patient? What disease does this patient have?
Click COMPLETE PATIENT C’S KARYOTYPE
13. Summarize (tell the main ideas) about Patient C’s medical history.
14. Count the total chromosomes in the karyotype.
15. The last set of chromosomes is the sex chromosomes. If you have 2 large chromosomes, your patient is XX
(female); one large and one small chromosome indicates XY (male). What sex chromosomes does your patient
have?
16. Which set has an extra chromosome?
17. What diagnosis would you give this patient? What disease does this patient have?
Do a webquest to find out about each of the diseases:
Disease
What it looks like on a karyotype
Klinefelter’s Syndrome
Trisomy 21 (Down’s Syndrome)
Trisomy 13
Go to: http://learn.genetics.utah.edu/content/begin/traits/predictdisorder/
Watch each of the first 5 files and answer the questions.
Normal Meiosis
1. How many human cells are made from meiosis?
2. How many chromosomes are in each cell?
Normal Fertilization
1. How many chromosomes are in a sperm or egg cell?
2. What is the new cell called when sperm and egg combine?
3. How many chromosomes are in the zygote?
Abnormal meiosis
1.
What happens to make meiosis abnormal (not correct or normal)?
What the symptoms are
Trisomy
1. Does trisomy happen before or after fertilization?
2. What does trisomy mean?
3. How can this happen?
Monosomy
1. Does monosomy happen before or after fertilization?
2. What does monosomy mean?
3. How can this happen?
Scroll to the bottom of the page and take the quiz.
Situation
Result
Situation
X+X
21X + 21X
No sex chs + X
XY + X
Y+X
21 + 21
Y +XX
X + no sex chs
Result