Online Appendix for the following August 1 JACC article TITLE: Antianginal Efficacy of Ranolazine When Added to Treatment With Amlodipine: The Efficacy of Ranolazine in Chronic Angina Trial AUTHORS: Peter H. Stone, MD, FACC, Brigham and Women’s Hospital, Cardiovascular Division, Boston, Massachusetts, Nikolay A. Gratsiansky, MD, Center for Atherosclerosis, Institute of Physico-Chemical Medicine, Moscow, Russia, Alexey Blokhin, MD, Outpatient Clinic of Medical Center of Russian Federation President’s Management Department, Moscow, Russia, I-Zu Huang, MD, CV Therapeutics, Palo Alto, California, Lixin Meng, MS, MPH, CV Therapeutics, Palo Alto, California on behalf of the ERICA Investigators APPENDIX Bulgaria Investigators Investigator Name Address Phone/Fax/E-mail Benov, Haralambi, Dr. Site Address: Multiprofile Hospital for Active Treatment "Dr. Stefan Cherkezov" 1, Nish St. 5000, Veliko Tarnovo, Bulgaria Phone: +359 62 479 11 Fax: +359 62 479 11 Grigorova, Valentina, Dr. Site Address: First Multiprofile Hospital for Active Treatment 35, Patriarh Evtimii Blvd. 1000, Sofia, Bulgaria Private Cardiology Practice Address: 33, Tsar Samuil Street 1000, Sofia, Bulgaria Phone: +359 2 953 1784 Fax: +359 2 953 1784 Mihov, Atanas, Dr. Site Address: Multiprofile Hospital for Active Treatment "Sveta Ekaterina" 26, Hristo Botev Street 6300, Dimitrovgrad, Bulgaria Phone: +359 391 63 494 Fax: +359 391 63 494 Perchev, Ivan, Assoc. Prof. Site Address: Fifth Multiprofile Hospital for Active Treatment Cardiology Clinic 67a Gen. Stoletov Blvd. 1233 Sofia, Bulgaria Phone: +359 2 926 8118 Fax: +359 2 926 8118 Raev, Dimitar, Assoc. Prof. Site Address: Medical Institute Central Clinical Hospital-Ministry of Interior Clinic of Cardiology and Intensive Care 79, Skobelev Blvd. 1606, Sofia, Bulgaria Phone: +359 2 982 72 647 Fax: +359 2 515 73 26 E-mail: raev@mvr.bg Tsanova, Veska, Dr. Site/Institution Address: National Multiprofile Transport Hospital "Tsar Boris III" Clinic of Cardiorheumatology 104, Maria Louisa Blvd. 1233, Sofia, Bulgaria Phone: +359 29 32 22 37 Fax: +359 29 31 16 50 Yordanova, Virginia, Dr. Site Address: Multiprofile Hospital for Active Treatment œ Pleven Clinic of Cardiology 8, Georgi Kochev St. 5800, Pleven, Bulgaria Phone: +359 64 427 556 Fax: +359 64 803 388 Canada Investigator Investigator Name Address Phone/Fax/E-mail Klinke, Peter, Dr. Site Address: Victoria Heart Institute Foundation 315-1900 Richmond Avenue Victoria British Columbia, V8R 4R2, Canada Phone: (250) 595-1884 Fax: (250) 595-5367 Georgia Investigators (Eastern Europe) Investigator Name Address Phone/Fax/E-mail Chapidze, Gulnara, Prof. Site/Office Address: Emergency Cardiology Centre 4, Lubliana Street 0159, Tbilisi, Georgia Phone: +995 32 98 52 60 Fax: +995 32 53 06 32 Chumburidze, Vakhtang, Prof. Site/Office Address: National Center of Therapy 3, Chachava Street 0159, Tbilisi, Georgia Phone: +995 32 51 70 06 Fax: +995 32 51 70 06 E-mail: vchumburidze@yahoo.com Emukhvari, Nodar, Prof. Site Address: Clinic N1 of the Tbilisi State Medical University 103, Uznadze Street 0102, Tbilisi, Georgia Phone: +995 32 96 95 88 Fax: +995 32 96 95 88 E-mail: ettset@posta.ge Kobulia, Bondo, Prof. Site/Office Address: Institute of Cardiology 2, Gudamakari Street 0141, Tbilisi, Georgia Phone: +995 32 60 75 35 (Office) Fax: +995 32 95 51 14 E-mail: drugmono@myoffice.ge Megreladze, Irakli, Prof. Site/Office Address: Cardiology Clinic 9, Tsinandali Street 0144, Tbilisi, Georgia Phone: +995 32 74 28 69 Fax: +995 32 92 02 98 E-mail: irameg@hotmail.com Melia, Anzor, MD, PhD Site Address: Cardiological Clinic "GULI" 9, Tsinandali Street 0144 Tbilisi, Georgia Phone: +995 32 94 00 11 Fax: +995 32 77 07 40 Paposhvili, Kakhi, MD Site/Office Address: Tbilisi Multiprofile Clinical Hospital #22, Constitution Street 0164, Tbilisi, Georgia Phone: +995 32 95 42 66 Fax: +995 32 95 98 45 E-mail: kakha@nilc.org.ge Shaburishvili, Tamaz, Prof. Site Address: Diagnostic Services Clinic 33, Chavchavadze Avenue 0179, Tbilisi, Georgia Phone: +995 32 25 10 00 Fax: +995 32 25 17 12 E-mail: cardvasc@access.sanet.ge Investigator Name Address Phone/Fax/E-mail Cristea, Madalina Ioana, MD Site Address: Medical Center for Ambulatory Diagnostic, Treatment and Preventive Medicine 8-10th Washington St., Sector 1 011794, Bucharest, Romania Phone: +40 07 21916099 Fax: +40 21 2300409 E-mail: oenache@cmdtamp.ro Tanaseanu, Cristina Mihaela, MD, PhD Site Address: "Sfantul Pantelimon" Clinical Emergency Hospital, Department of Internal Medicine 340œ342th Pantelimon Avenue, Sector 2 021659, Bucharest, Romania Phone: +40 21 2554025 Fax: +40 21 2552329 E-mail: mpopescumail@yahoo.com Investigator Name Address Phone/Fax/E-mail Aleksandrov, Andrey, Prof. Site Address: Endocrinology Scientific Center of Russian Academy of Medical Science, Cardiology Department 11, Dmitry Ulyanov Street 117036, Moscow, Russia Phone: +7 095 126 21 14 Fax: +7 095 718 05 22 Andreev, Denis, MD., PhD Site/Institution/Office Address: Problem Laboratory for Drugs Development, Investigation, Application, Manufacturing and Marketing of Medications of RAMS based at "Medsantrud" City Hospital #23 11/5, Yauzskaya Street 109240, Moscow, Russia Phone: +7 095 915 72 64 Fax: +7 095 915 72 64 E-mail: dennan@mail.ru Ballyuzek, Marina F., Prof. Site Address: Saint-Petersburg Clinical Hospital of Russian Academy of Sciences Outpatient Department 72, Morisa Toreza Avenue 194017, Saint-Petersburg, Russia Phone: +7 812 553 33 98 Fax: +7 812 553 33 98 E-mail: Marina.Ballyzek@mail.ioffe.ru Baranova, Elena, Prof. Site Address: Saint-Petersburg State Medical University n.a. Academician I.P. Pavlov Institute of Cardiovascular Diseases 6/8, L. Tolstoy Street 197022, Saint-Petersburg, Russia Phone: +7 812 234 90 82 Fax: +7 812 234 90 82 E-mail: elena@spmu.rssi.ru Barbarash, Olga L. Prof. Site Address: Kemerovo State Medical Academy Department of Cardiology and Cardiovascular Surgery based at Kemerovo Cardiology Dispensary 6, Sosnovy Blvd. 650002, Kemerovo, Russia Phone: +7 384 252 14 74 Fax: +7 384 252 14 74 E-mail: olb@relay.kuzbass.net Romania Investigators Russia Investigators Barbarich, Vladimir B., MD Site Address: State Clinical Immunology Research Institute Department of Internal Medicine 6, Zalesskogo Street 630047, Novosibirsk, Russia Phone: +7 383 225 59 36 Phone: +7 383 228 25 47 Fax: +7 3832 25 05 22 E-mail: ivs@online.nsk.ru Belousov, Yuri, Prof. Site Address: Russian State Medical University, Department of Clinical Pharmacology based at City Hospital #6 26/4, Novobasmannaya Street 107066, Moscow, Russia Phone: +7 095 261 25 90 Fax: +7 095 261 65 10 E-mail: belouspharma@mtunet.ru Blokhin, Alexey, MD, PhD Site Address: Outpatient Clinic #1 of Medical Center of Russian Federation President's Management Department 31, Grokholsky Lane 129010, Moscow, Russia Phone: +7 095 280 96 01 Fax: +7 095 280 96 01 E-mail: bab@pmc.ru Bootomo, Maria, MD, PhD Site/Office Address: Saint-Petersburg State Medical University n.a. Academician I.P. Pavlov Hospital Therapy Chair and Department 6/8, L. Tolstoy Street 197022, Saint-Petersburg, Russia Phone: +7 812 233 44 96 Fax: +7 812 326 61 94 Esip, Valeria, Dr. Site/Office Address: Diagnostic Center #85 89/3, Prospect Veteranov 198260, SaintPetersburg, Russia Phone: +7 812 900 7751 Fax: +7 812 152 27 20 E-mail: esip_lera@fromru.com Fitilev, Sergey, Prof. Site Address: Central Medical Division #47 (Glavmosstroy Hospital) 56, Michurinsky Prospect 117192, Moscow, Russia Phone: +7 0959 32 37 01 Fax: +7 0959 32 37 01 E-mail: clphtest@yandex.ru Gordeev, Ivan, MD, PhD Site Address: Russian State Medical University of Ministry of Health of Russian Federation Department of Hospital Therapy #1 based at O.M. Filatov City Clinical Hospital #15 23/Main Building, Veshnyakovskaya Street 111539, Moscow, Russia Phone: +7 095 918 72 84 Fax: +7 095 918 72 84 E-mail: Cardio-15@yandex.ru Gratsiansky, Nikolai, Prof. Site Address: Laboratory of Clinical Cardiology based at Bauman City Hospital #29 Corp. 3, 2, Hospitalnaya Sq. 111020, Moscow, Russia Office Address: 1A, M. Pirogovskaya Street 119992, Moscow, Russia Phone: +7 095 261 43 45 Fax: +7 095 261 46 44 E-mail: n.gra@relcom.ru Jakushin, Sergej, Prof. Site Address: Rjazan State Medical University n.a. Academician I.P. Pavlov, Chair of Hospital Therapy with Course of OutPatient Clinic Therapy based at Rjazan Regional Clinical Cardiology Dispensary 96, Strojcova Street 390026, Rjazan, Russia Phone: +7 0912 76 84 06 Fax: +7 0912 76 84 06 E-mail: yakushin@kafedra.ryazan.ru Kostenko, Viktor, Dr. Site Address: St. Petersburg Dzhanelidze Research Institute for Emergency Medical Care, Cardiology Department 3, Budapeshtskaya Street 192242, SaintPetersburg, Russia Phone: +7 812 174 91 64 Fax: +7 812 109 60 90 E-mail: vico@ccu.emergency.spb.ru Kukharchuk, Valery, Prof. Site/Office Address: Russian Cardiology Research Complex, Myasnikov Clinical Cardiology Institute, Laboratory of Haemodialysis and Plasmapheresis 15-A/9, 3rd Cherepkovskaya Street 121552, Moscow, Russia Phone: +7 095 149 01 41 Fax: +7 095 414 66 68 E-mail: vkukharch@mtu-net.ru Kuleshova, Elvira V., Prof. Site Address: Almazov State Research Institute of Cardiology Department of Coronary Artery Disease 15, Parkhomenko Avenue 194156, Saint-Petersburg, Russia Phone: +7 812 552 87 51 Fax: +7 812 244 29 70 E-mail: natl03@rol.ru Martynov, Anatoly, Acad. Site Address: Moscow State Medical Dentistry University, Hospital Therapy Department #1 based at City Clinical Hospital #40 7/6, Kasatkina Street 129301, Moscow, Russia Mailing Address: Moscow State Medical Dentistry University 20/1, Delegatskaya Street 127473, Moscow, Russia Phone: +7 095 286 32 21 Fax: +7 095 286 52 16 E-mail: kafedra1@mtu-net.ru Milyagin, Viktor, Prof. Site Address: Smolensk State Medical Academy "Diagnostics and Medical Agents Clinical Trials Center" 27, Prospect Gagarina 214018, Smolensk, Russia Phone: +7 081 261 13 27 Phone: +7 081 261 13 01 Fax: +7 081 261 12 94 E-mail: olga@antibiotic.ru Perepech, Nikita B., Prof. Site Address: Saint-Petersburg Mechnikov State Medical Academy of Ministry of Health of Russian Federation Faculty of Postgraduate Education Chair of Cardiology based at City Hospital #31 Cardiology Department #5 3, Dinamo Avenue 197110, Saint-Petersburg, Russia Phone: +7 812 230 67 60 Fax: +7 812 230 67 60 E-mail: irinamikhailova@mail.ru Rebrov, Andrey, Prof. Site Address: Saratov State Medical University, Hospital Therapy Department Based at Saratov Regional Clinical Hospital 1, Smirnovskoe Ravine 410053, Saratov, Russia Phone: +7 845 251 49 60 Fax: +7 845 252 02 53 E-mail: rebrov@sgu.ru Rudakova, Tamara, Prof. Site Address: Saint-Petersburg State Medical University n.a. Academician I.P. Pavlov of Ministry Faculty Therapy Chair and Department 6/8, L. Tolstoy Street 197022, Saint-Petersburg, Russia Phone: +7 812 238 71 25 Fax: +7 812 238 71 25 E-mail: rutl@spmu.rssi.ru Shalnova, Svetlana, Prof. Site Address: State Research Center for Preventive Medicine of Ministry of Health of Russian Federation 10, Petroverigsky Lane 101990, Moscow, Russia Phone: +7 095 925 45 44 Fax: +7 095 928 57 52 E-mail: sshalnova@gnicpm.ru Shilkina, Nataliya, Prof. Site Address: City Healthcare Institution Clinical Hospital #8 Cardiology Department 39, Suzdalskoye Avenue 150030, Yaroslavl, Russia Phone: +7 0852 44 54 04 Fax: +7 0852 44 54 14 E-mail: hosp8nm@mail.yar.ru Shubik, Yuri, Prof. Site Address: Northwestern Center of Diagnostic and Therapy of Arrhythmias attached to Saint-Petersburg Mechnikov State Medical Academy of Ministry of Health of Russian Federation 8, Deputatskaya Street, Krestovsky Ostrov 197110, Saint-Petersburg, Russia Phone: +7 812 235 70 41 Fax: +7 812 235 70 41 E-mail: vshubik@mail.ru Shvarts, Yury, Prof. Site/Office Address: Saratov State Medical University, Faculty Therapy Chair based at City Hospital #3, Cardiology Department 137, Bolshaya Sadovaya Street 410054, Saratov, Russia Phone: +7 845 235 70 41 Fax: +7 845 235 70 41 E-mail: shwartz@forpost.ru Sidorenko, Boris, Prof. Site Address: Educational Research Centre of Medical Centre of Russian Federation President's Management Department, Department of Cardiology and General Therapy, Central Clinical Hospital 15, Marshal Timoshenko Street 121359, Moscow, Russia Phone: +7 095 414 05 17 Fax: +7 095 414 05 17 E-mail: kardiosid@cch.pmc.ru Vishnevskiy, Alexander, Dr. Site/Institution Address: Pokrovskaya City Hospital Cardiology Department #3 85, Bolshoy Prospect V.O. 199106, SaintPetersburg, Russia Phone: +7 812 322 10 41 Fax: +7 812 322 04 20 E-mail: alvishn@pokrov.spb.ru United States Investigators Investigator Name Address Phone/Fax/E-mail Henry, Timothy, MD Site/Office Address: Minneapolis Heart Institute Foundation Department of Research 920 East 28th Street, Suite 40 Minneapolis, MN 55407, USA Phone: (612) 863-3976 Fax: (612) 863-2490 Email: henry003@umn.edu Smith, William B., MD Site/Office Address: New Orleans Center for Clinical Research 2820 Canal Street New Orleans, LA 70119, USA Office Addresses: New Orleans Center for Clinical Research 1040 Calhoun Street Helis Bldg., 2nd & 3rd Floors New Orleans, LA 70118, USA Canal Street Cardiology Associates 2820 Canal Street New Orleans, LA 70119, USA Volunteer Research Group University of Tennessee Medical Center 1928 Alcoa Highway, Suite G50 Knoxville, TN 37920, USA Phone: (504) 821-8158 Fax: (504) 821-8343 E-mail: wbsmd@noccr.com The randomization was managed by Dynarand (now United BioSource Corporation), 55 Francisco St. Suite 780, San Francisco, CA 94133. Phone: 888-794-4877. Statistical analyses were conducted by CV Therapeutics, Inc.