Cellular Basis of Nutrition Instructor: Shere Byrd Office: 790 Berndt Hall Office Hours: 11-12; MWF; 11-12 Th; others as needed Email: byrd_s@fortlewis.edu Webpage: http://faculty.fortlewis.edu/byrd_s Course Description In this course students will investigate the cellular role of the major vitamins, minerals, and other nutrients. We will also explore the scientific efficacy of natural supplements by examining purported use for the supplement, and evidence supporting those claims. Students should have a general understanding of basic chemistry and cellular metabolic processes. Required Texts 1. Advanced Nutrition and Human Metabolism. SS Gropper, JL Smith, and JL Groff. 4th Edition. Thomson Wadsworth Publishing, 2005. 2. Natural Health Bible. Bratman, and Kroll. 2nd Edition. Three Rivers Press, 2000. Suggested, but Optional Texts: 1. General Physiology text 2. General Biochemistry text Grading Exams – Each worth 100 points Group Presentation – Popular Diets Compared 100 points Cooperative Learning Groups – Case Study Presentations 100 points List item expansion – 50 points each Final grades will be based on a 90%-80%-70%-60%-50% scale, with no curving. 90%+ = A, etc. All assignments must be typewritten. If you use outside sources for assignments, Web resources are a fine starting point, but should not replace peer-reviewed, library resources. Assignments must be turned in on time for full credit. There will be 5% loss in possible points per day late. No late assignment will be accepted after the instructor has graded and turned that assignment back. Make-up exams may be given at the discretion of the instructor, if arrangements have been made PRIOR to the exam date. Plagiarism As with any course, plagiarism of any written or other assignment will result in a failing (F) grade. If you are unsure whether you understand what plagiarism is (ie. copying work word-for-word, using web materials verbatim, looking at someone’s work and writing down their answer – also called cheating) please come and see me and we can discuss appropriate citation usage. Disabilities Students with disabilities have equal access and equal opportunity in this course. If you require reasonable accommodations to fully participate in course activities or meet course requirements, you must register with Disability Services, 280 Noble Hall, 247-7459. If you qualify for services, bring your letter of accommodation to me as soon as possible. Classroom behavior Students are expected to adhere to Fort Lewis College student behavior policies. Tolerance of individual viewpoints and civil behavior toward fellow students and me is required. Classes work best if students arrive on time. I respect the fact that everyone has a life outside of the college, but ask to be informed when your life interferes with your ability to participate in classroom activities, or to fulfill assignments. Grievance processes: If you feel that you have not been treated fairly by your peers or by me during this course, there is a grievance process outlined on the Fort Lewis College website at http://www.fortlewis.edu/current_students/student_grievance/default.asp#top Tentative Schedule Please come to class for updates and possible changes to this schedule. Exam dates will NOT CHANGE under any circumstances) ANM = Advanced Nutrition and Human Metabolism NHB = Natural Health Bible Week Date Readings Topics/ Questions 1 8.29 to 9.2 2 9.5 to 9.9 9.12 to 9.16 9.19 to 9.23 ANM -Review Ch1; Read to discuss Ch2 NHB – List #1 (see attached at back of syllabus) ANM – Read to discuss Ch 16; Phytochemicals p. 123-127 NHB – XV-XVII ANM – Review Ch 3; Read to discuss Ch. 4 NHB - p 65-69; List #2 ANM - Read to discuss Ch 5 NHB – p.37, 57-58, 91, 19394;108-09 Case Study #1 ANM – Read to discuss Ch 6 NHB – p. 16-21, 88-93; List #4 ANM – Read to discuss Ch 7 NHB – p.163,208,310,350, 376 Exam 1 Monday, Oct. 3 ANM – read to discuss Ch 15 NHB – pp 192-96; 251,395, 328, 277, 261, 304, 413, 198 Reserve Readings Presentations Class organization; expectations; policies How does our digestive system do its thing? What regulates the process? What can happen when things go wrong? Nutrition research design and analysis Herbal supplements - phytochemicals 3 4 5 9.26 to 9.30 6 10.3 to 10.7 7 10.10 to 10.14 10.17 to 10.21 10.24 8 9 10 10.31 to 11.4 Reserve Readings & List #3 Presentations ANM – Read to discuss Ch 9 NHB -9,40, 55, 97, 43, 122, 436, 23, 67, 69, 91, 438-39, 3,16, 17, 64, 78, 111, 28,116, 51 ANM - Ch 9 (continued) ANM – Read to discuss Ch 10 NHB – 2, 32, 46, 56, 433-34 Carbs – Sweets – Starch The “sweet and low” on sugars. Diabetes and other diseases related to carbohydrate metabolism. Dietary fiber – what’s with Metamucil? More about your bowels than you’ll ever want to know…… Fat – Adipose – Lipid – Cellulite – Beer Belly – Love Handles – Saddlebags - What do we do with it all? Protein: Not all amino acids are equal Exam 1 over Chapters 2,4-7, 16 Body Composition and Energy Expenditure You are what you do or don’t metabolize Popular diets; pros and cons Class presentations NO CLASS ON FRIDAY, OCTOBER 14 Popular diets; pros and cons Class presentations Bring Your Diet Food Buffet – Friday 10/21 Water soluble vitamins – Bs (Have you had your Wheaties today?) and C (Linus Pauling can’t be all wrong) Water soluble vitamins (continued) Fat-soluble vitamins (DEAK) – Great for your eyes, brain, and blood 11 12 13 14 15 11.7 to 11.11 11.14 11.21 to 11.25 11.28 to 12.2 12.5 to 12.9 ANM - Ch 10 (continued) Case Study #2 Fat soluble vitamins (continued) ANM – Read to discuss Ch 11 NHB – 234-37, 136-139, 145147, 351-53, 120-22, 390, Thanksgiving Macrominerals (Ca,Cl,Mg,PO4,K,Na, S) ANM – Ch 11 (continued) ANM – Read to discuss Ch 13 NHB – 251-53, 262, 33135354-55, 407-09, 463-65 ANM- Ch 13 (continued) ANM – Read to discuss Ch 14 NHB – 227, 430-431, Final Exam 9:45-11:45 am Wednesday, December 14 Macrominerals (continued) Microminerals – Minute but important Cr, Cu, Fl, I, Fe, Mn, Mb,Se,Zn Thanksgiving Microminerals (continued Ultratrace minerals – A little bit goes a long way! As, B, Ni, Si, Vn Instructions for List “Expansion” Type a one page analysis of the chosen list item. For list items that are a disease/ailment, the analysis should include: 1. A description of the symptoms of the particular ailment 2. A description of the underlying etiology (cause(s)) of the disease/ailment 3. How the disease/ailment is linked to nutrition. For a list item that is a nutritional herb or supplement the analysis should include: 1. The scientifically validated uses of the supplement or herb, 2. The nutritional function/metabolic pathways it is involved in, 3. The active ingredient, if known. These mini-analyses must be supported by scientifically validated literature. A list of those references must be included. Each list analysis is due 1 week following its assignment in class. List #1 GI ulcers Nausea Liver cirrhosis Kidney stones Irritable bowel syndrome Gallstones Eating disorder Bullemia Anorexia Constipation Colic List #2 Carnitine Aloe CoQ10 Fenugreek Glucomannan Gymnema List #3 Diet for Altitude sickness Cancer prevention Candida Chronic obstructive pulmonary disease Colic (list #3 continued) Cyclic mastalgia Interstitial cystitis Osteoarthritis Kidney stones Angina Atherosclerosis High cholesterol Insomnia List #4 Fish oil Flaxseed oil Green tea GAGs Magnesium DHEA Genistein Garlic Red yeast rice Stanols B3 Soy Policosanol Artichoke leaf