NURSING DEPARTMENT
Date
Course Title
Nursing Math and
Pharmacology
Credits
Course
Number
3 credits
NUR 1141
MAT0002, DEP 1000,
Co-requisite None
NUR 1889, 1822, 1045,
(s)
1025, 1025C, 1025L
Hours
45 theory hours/45 clock Total outside 90 hours
hours
hours
Note: A minimum of 2 hours of outside work is assigned per clock hour.
Pre-requisite (s)
Place and Time of Class Meeting
Institute of Healthcare Professions
2100 45th Street, Suite A2A
West Palm Beach, FL 33407
Hybrid
Name and Contact Information of Instructor
Instructor: Johnnetta Wider RN, MSN
Email: JWider@ihpedu.com
Office Hours: By Appointment
Campus Telephone: (561) 202-6333
Method of Delivery: Online
Book required
Pharmacology: Connections to Nursing Practice, 2/e, Michael Adams & Carol Urban
©2012 | Pearson | Published: 2/2012
ISBN-13:978-0132814423
Classroom expectations for students
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NURSING DEPARTMENT
Attendance Policy
Students are expected to participate in all required instructional activities in their
courses. Online courses are no different in this regard; however, participation must be defined in
a different manner.
1. Student “attendance” in an online course is defined as active participation in the
course as described in the course syllabus. Instructors are responsible for incorporating specific
instructional activities within their course and will, at a minimum, have weekly mechanisms for
documenting student participation. These mechanisms may include, but are not limited to,
participating in a weekly discussion board, submitting/completing assignments in the online
platform, or communicating with the instructor.
2. Students aware of necessary absences must inform the professor with as much advance
notice as possible in order to make appropriate arrangements.
3. Any student absent 20 percent or more of the online course, i.e., non-participatory during
3 or more weeks of an 11 week term, may receive an F for that course.
4. Any student who has not actively participated in an online class prior to the census date
for any given term is considered a "no-show" and will be administratively withdrawn from
the class without record. To be counted as actively participating, it is not sufficient to log in
and view the course. The student must be submitting work as described in the course
syllabus.
5. Additional attendance and participation policies for each course, as defined by the
instructor in the course syllabus, are considered a part of the attendance policy
Termination may occur for any of the following attendance situations:
1. Eight (8) consecutive absences per semester.
2. Absence in excess of 20 percent (20%) of available course hours.
3. Absence in excess of 20 percent (20%) of externship hours.
Student Tardiness Policy
Tardiness for didactic or clinical education will not be tolerated. Anytime beyond the scheduled
reporting time will be considered late or tardy. When attending clinical externship, if a student is
to be late, he or she must notify the clinical instructor at the facility and the program clinical
coordinator. If a student must miss class, he or she must contact the program director or
instructor at least 30 minutes prior to the class beginning for didactic education five episodes of
tardiness or leaving IHP early per semester will result in an absence.
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NURSING DEPARTMENT
NOTE: Plagiarism is defined as the use, without proper acknowledgment, of the ideas, phrases,
sentences, or larger units of discourse from another writer or speaker. Plagiarism includes the
unauthorized copying of software and the violation of copyright laws. Students who commit
plagiarism will obtain a grade of “Failure” on their exam or assignment.
Course Description (must correspond exactly to Catalog description)
This course combines theory and laboratory experiences to allow for mastery of the basic
principles of pharmacotherapeutics and the role of the nurse in safe effective administration of
medications with emphasis places on dosage calculations.
Learning Objectives
The primary goal is to establish knowledge and skills for the safety administration of drug
therapy within the role of the registered professional nurse.
STUDENT LEARNING OUTCOMES (SLO)
All students successfully completing this course will be able to:
1.1.Collect, analyze, and prioritize relevant physical, developmental, psychosocial, cultural,
spiritual, and functional assessment data to provide individualized patient care.
2 2. Utilize the nursing process, critical thinking, evidence-based information, and knowledge
from the arts and sciences to support sound clinical decisions.
3 3. Communicate effectively through verbal, nonverbal, written, and technological means with
individuals, families, and health care team members.
4 4. Plan and implement nursing care in a safe, compassionate, culturally sensitive manner that
preserves human dignity and promotes growth of individuals and families.
5 5. Manage the efficient, effective use of human, physical, financial, and technological
resources in providing continuity of care within and across healthcare settings.
6 6. Collaborate with individuals, families, and healthcare team members in providing
comprehensive, individualized patient care.
7 7. Demonstrate accountability in adhering to standards of professional practice within legal
and ethical frameworks.
8.8. Participate in activities that promote professional development and personal growth.
COURSE OBJECTIVES (CO)
All students successfully completing this course will be able to:
1. Describe the mechanism of action, therapeutic uses, side effects, and adverse reactions for
each major drug class. (SLO – 1, 2)
2. Discuss basic physiological and pathophysiological mechanisms involved in the rationale for
drug therapy. (SLO – 1, 2)
3. Examine recent research findings and developments related to drug therapy. (SLO-2)
4. Demonstrate the ability to accurately calculate drug dosages. (SLO- 3,4, 5)
5. Identify physical, developmental, psychosocial, religious, and cultural factors that impact
drug therapy. (SLO-1, 3, 4, 6)
6. Describe the nursing interventions and patient education necessary for safe administration of
the major drug classes. (SLO– 2, 3, 5, 7)
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NURSING DEPARTMENT
7. Explain the nurse’s role in teaching patients receiving drug therapy. (SLO – 3, 5)
8. Identify the legal and ethical standards related to the nurse’s role in drug therapy. (SLO – 3, 7)
9. Recognize the responsibility for continued learning regarding drug therapy. (SLO –3, 8)
Topical Outline and Schedule
DATE
WEEK 1
Describe the course.
SPECIFIC
OBJECTIVES Discuss the library and library resources.
1. Identify key events in the history of pharmacology.
2. Compare and contrast the terms drug, pharmacology, and
pharmacotherapy.
3. Explain the importance of pharmacotherapy to clinical nursing
practice.
4. Using specific examples, explain the difference between the
pharmacologic and therapeutic methods of classifying drugs.
5. Identify the advantages of using protype drugs to study pharmacology
6. Classify drugs by their chemical, generic and trade names
7. Compare the advantages and disadvantages of a pharmaceutical
company being granted exclusivity for the development of a new drug
8. Analyze possible differences generic drugs and their brand-name
equivalents
9. Assess the responsibilities of the nurse in drug administration.
10. Explain the role of patient medicines in the history of pharmacology
and the legislation of drugs.
11. Outline the key U.S. drug regulations and explain how each has
contributed to the safety and effectiveness of medications
12. Describe how the United States Pharmacopia-National Formulary
(USP-NF) controls drug purity and standards
13. Evaluate the role of the U.S. Food and Drug Administration in the drug
approval process.
14. Categorize the four stages of new drug testing
15. Discuss how recent changes to the approval process have increased the
speed at which new drugs reach consumers.
16. Compare and contrast prescription and over-the-counter drugs
17. Explain how scheduled drugs are classified and regulated
18. Describe the Canadian drug approval process and identify similarities
to the drug approval process in the United States.
19. Outline a plan for improving patient adherence to the medical regimen.
20. Describe how the storage of drugs can affect their effectiveness.
21. Describe the components of a legal prescription and the abbreviations
associated with drug orders.
22. Outline a plan for improving patient adherence to the medical regimen.
23. Describe how the storage of drugs can affect their effectiveness.
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NURSING DEPARTMENT
24. Describe the components of a legal prescription and the abbreviations
associated with drug orders.
TOPIC (S)
LEARNING
ACTIVITIES
Syllabus
Introduction to Pharmacology: Concepts and Connections
Drug Regulations
Principles of Drug Administration
Chapters 1,2,3 (CO 1,2,3,4,8,9)
Complete Math assignment
Quiz 1 covering Chapters 1-3 ( available Wednesday- Saturday 11:55 pm
EST)
Chapter readings: Chapters 6,7,9,15,36
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
Week 2
At the end of this lesson, you will be able to:
SPECIFIC
OBJECTIVES 1. Differentiate health care services based on primary, secondary and tertiary
disease prevention categories.
2. Outline a plan for improving patient adherence to the medical regimen.
3. Describe how the storage of drugs can affect their effectiveness.
4. Describe the components of a legal prescription and the abbreviations
associated with drug orders.
5. Explain how idiosyncratic reactions differ from other types of adverse
effects.
6. Explain why certain drugs with carcinogenic or teratogenic potential are
used in pharmacotherapy.
7. Report the characteristic signs, symptoms, and treatment for each of the
following organ-specific adverse events: nephrotoxicity, neurotoxicity,
hepatotoxicity, dermatologic toxicity, bone marrow toxicity,
cardiotoxicity, and skeletal muscle toxicity.
8. Use examples to explain the importance of drug interactions to
pharmacotherapy.
9. Describe the mechanisms of drug interactions that alter absorption,
distribution, metabolism, or excretion.
10. Differentiate among additive, synergistic, and antagonistic drug
interactions.
11. Identify examples of drug–food interactions that may impact
pharmacotherapeutic outcomes.
12. Identify examples of drug–food interactions that may impact
pharmacotherapeutic outcomes.
13. Identify examples of drug–food interactions that may impact
pharmacotherapeutic outcomes.
14. Identify examples of drug–food interactions that may impact
pharmacotherapeutic outcomes.
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NURSING DEPARTMENT
15. Identify efforts recommended by health care agencies to monitor
medication errors and provide information to health care providers
16. Compare and contrast the different phases of the nursing process.
17. Provide examples of how the nursing process is used during
pharmacotherapy.
18. Identify the purposes of collecting data in the assessment phase of the
nursing process.
19. Explain how nursing diagnoses are identified and worded.
20. Describe the steps in the planning phase of the nursing process.
21. Identify specific pharmacology topics employed in the implementation
phase of the nursing process.
22. Explain the purpose of the evaluation phase in the nursing process.
23. Explain what actions follow the evaluation phase of the nursing process.
24. Explain the role of complementary and alternative therapies in promoting
patient wellness.
25. Analyze why herbal and dietary supplements have increased in popularity.
26. Identify the parts of an herb that contain active ingredients and the types of
formulations made from these parts.
27. Compare the strengths and weaknesses of the Dietary Supplement Health
and Education Act of 1994 with the Dietary Supplement and
Nonprescription Drug Consumer Protection Act of 2006.
28. Describe specific adverse effects that may be caused by herbal
preparations.
29. Discuss the role of the nurse in teaching patients about complementary and
alternative therapies.
30. Identify common drug–herb interactions.
31. Explain why it is important to standardize herbal products based on
specific active ingredients.
32. Describe the exchange of fluids that occurs among the different fluid
compartments in the body.
33. Identify conditions for which intravenous fluid therapy may be indicated.
34. Explain how changes in the osmolality or tonicity of a fluid can cause
water to move to a different compartment.
35. Compare and contrast the use of blood products, crystalloids, and colloids
in intravenous therapy.
36. Explain the importance of electrolyte balance in the body.
37. Explain the pharmacotherapy of sodium and potassium imbalances.
38. Discuss medications used to treat acidosis and alkalosis.
39. Describe the nurse’s role in the pharmacologic management of fluid
imbalance, electrolyte, and acid–base disorders.
40. For each of the classes shown in the chapter outline, identify the prototype
and representative drugs and explain the mechanism(s) of drug action,
primary indications, contraindications, significant drug interactions,
pregnancy category, and important adverse effects.
41. Apply the nursing process to care for patients receiving drug therapy for
fluid imbalance, electrolyte, and acid–base disorders.
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NURSING DEPARTMENT
TOPIC (S)
LEARNING
ACTIVITIES
OUTSIDE
WORK &
ASSIGNED
READINGS
Adverse Drug Effects and Drug Interactions
Medication Errors and Risk Reduction
Pharmacology and the Nursing Process
The Role of Complementary and Alternative Therapies in Pharmacotherapy
Discussions
PowerPoints
Chapters 6,7,9,15,36
Quiz 2 covering Chapters 6,7,9,15,36
Biphosphonate Therapy Case Study
Cellular Disorders
Read: Ch. 49,50,51,52,53
WEEK 3
SPECIFIC
At the end of this lesson, you will be able to:
OBJECTIVES
1. Explain the mechanisms by which pathogens infect the body.
2. Describe methods for classifying bacteria.
3. Explain the mechanisms by which anti-infective drugs act to kill
pathogens or restrict their growth.
4. Describe the clinical significance of bacterial resistance
5. Identify steps that the nurse can take to limit the development of
resistance.
6. Describe the clinical rationale for selecting specific antibiotics.
7. Identify the role of the nurse in preventing, identifying, and treating
adverse effects due to antibiotic therapy.
8. Explain how the patient’s immune status, history of allergic reactions,
age, pregnancy status, genetics, or local tissue conditions influence
anti-infective pharmacotherapy.
9. Explain the clinical importance of selecting the correct antibiotic for
the individual patient.
10. Describe the development of superinfections.
11. Explain the structure of a bacterial cell wall and its importance to
pharmacotherapy.
12. Identify the classes of antibiotics that act by affecting the synthesis of
the bacterial cell wall.
13. Explain the mechanisms by which antibiotics affect the bacterial cell
wall.
14. Compare and contrast the four classes of penicillins.
15. Compare and contrast the five generations of cephalosporins.
16. Identify similarities and differences among drugs in the carbapenem
class
17. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
18. Apply the nursing process to care for patients who are receiving
pharmacotherapy with bacterial cell wall inhibitors.
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NURSING DEPARTMENT
TOPIC (S)
LEARNING
ACTIVITIES
19. Explain the steps in the synthesis of bacterial proteins.
20. Identify the classes of antibiotics that act by inhibiting bacterial protein
synthesis.
21. Explain mechanisms by which antibiotics inhibit bacterial protein
synthesis.
22. Explain how protein synthesis inhibitors exert selective toxicity toward
bacterial, rather than human, cells.
23. Describe means by which bacteria become resistant to protein
synthesis inhibitors.
24. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
25. Apply the nursing process to care for patients who are receiving
pharmacotherapy with bacterial protein synthesis inhibitors.
Basic Principles of Anti-Infective Pharmacotherapy
Antibiotics Affecting the Bacterial Cell Wall
Antibiotics Affecting Bacterial Protein Synthesis
Chapter readings
Discussion post
Case Study
Quiz 3: covering : Ch. 49,50,51,52,53
Read: Cellular Disorders Chapters 54,55,56,57,58
Case Study
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
WEEK 4
At
the
end
of
this
lesson,
you
will
be
able to:
SPECIFIC
1. Compare and contrast the types of infections caused by mycobacteria.
OBJECTIVES
2. Explain the pathogenesis of tuberculosis.
3. Describe how the pharmacotherapy of tuberculosis differs from that of
bacterial infections.
4. Identify the most common drug regimens for treating tuberculosis.
5. Compare and contrast the types of infections caused by mycobacteria.
6. Explain the pathogenesis of tuberculosis.
7. Describe how the pharmacotherapy of tuberculosis differs from that of
bacterial infections.
8. Identify the most common drug regimens for treating tuberculosis.
9. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
10. Explain significant patient variables that must be considered for
effective pharmacotherapy with antimycobacterial drugs.
11. Apply the nursing process to care for patients receiving
pharmacotherapy for mycobacterial infections.
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NURSING DEPARTMENT
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
Compare and contrast the pharmacotherapy of fungal and bacterial
infections.
Classify mycoses based on the location of the infection and the
causative organism.
Compare and contrast the pharmacotherapy of superficial and systemic
fungal infections.
Identify the types of patients at greatest risk of acquiring serious fungal
infections.
Describe the nurse’s role in the pharmacologic management of fungal
infections.
For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
Apply the nursing process to care for patients receiving
pharmacotherapy for fungal infections.
Identify features of protozoa and helminths that distinguish them from
bacteria.
Identify protozoan and helminthic infections that may benefit from
pharmacotherapy.
Explain why an understanding of Plasmodium’s life cycle is important
to the successful pharmacotherapy of malaria.
Explain the etiology, pathogenesis, and pharmacotherapy of amebiasis,
giardiasis, cryptosporidiosis, toxoplasmosis, trichomoniasis,
trypanosomiasis, and leishmaniasis.
Explain the etiology, pathogenesis, and pharmacotherapy of ascariasis,
enterobiasis, hookworm, and tapeworm infections.
Describe the nurse’s role in the pharmacologic management of
protozoan and helminthic infections
For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
Apply the nursing process to care for patients receiving
pharmacotherapy for protozoan and helminthic infections.
Describe the major structural components of viruses.
Identify viral infections that benefit from pharmacotherapy.
Explain the five principal stages in the pathogenesis of a viral
infection.
Explain general principles related to the pharmacotherapy of viral
infections.
Describe the nurse’s role in the pharmacologic management of patients
receiving medications for herpes viruses, influenza viruses, and
hepatitis viruses.
For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
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NURSING DEPARTMENT
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
TOPIC (S)
LEARNING
ACTIVITIES
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
Apply the nursing process to care for patients receiving
pharmacotherapy for viral infections.
Describe the primary steps in the pathogenesis of HIV infection.
Explain reasons for treatment failure during HIV-AIDS
pharmacotherapy.
Explain the purpose and expected outcomes of HIV-AIDS
pharmacotherapy.
Describe the advantages of highly active antiretroviral therapy in the
pharmacotherapy of HIV infection.
Compare and contrast the six classes of antiretroviral medications.
Describe the difficulties in developing a vaccine to prevent HIV-AIDS.
Explain the protocol and rationale for postexposure prophylaxis
following occupational exposure to HIV-infected fluids.
Describe the antiretroviral protocol used for reducing the risk of
perinatal transmission and for treating pediatric patients with HIVAIDS.
Identify opportunistic infections commonly acquired by patients with
AIDS and the drugs used to treat them.
Describe the nurse’s role in the pharmacologic management of patients
receiving antiretroviral medications.
For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
Apply the nursing process to care for patients receiving
pharmacotherapy for HIV-AIDS.
Pharmacotherapy of Mycobacterial Infections
Pharmacotherapy of Fungal Infections
Pharmacotherapy of Protozoan and Helminthic Infections
Pharmacotherapy of Non-HIV Infections
Pharmacotherapy of HIV-AIDS
Chapter readings
Discussion post
Quiz covering : Chapters 54,55,56,57,58
Read: Immunological Disorders Chapters 43,44,45,46
Read: Integumentary Disorders Chapter 76
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
WEEK 5
At the end of this lesson, you will be able to:
SPECIFIC
OBJECTIVES 1. Identify the major components of the lymphatic system.
2. Describe the components of the nonspecific body defense system and their
functions.
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NURSING DEPARTMENT
3. Compare and contrast specific and nonspecific body defenses.
4. Identify the signs and symptoms of inflammation.
5.Outline the basic steps in the acute inflammatory response.
6.Explain the role of histamine and other chemical mediators in the
inflammatory response.
7. Compare and contrast the humoral and cell-mediated immune responses.
8.Explain the pathophysiology of inflammation and fever.
9.Identify drug classes used to treat inflammation and fever.
10.Explain how aspirin damages the gastrointestinal mucosa.
11.Describe the symptoms and treatment of salicylism.
12.Compare the actions and adverse effects of aspirin to ibuprofen and
ibuprofen-like drugs.
13.Compare the actions and adverse effects of the cyclooxygenase-2 inhibitors
to other nonsteroidal anti-inflammatory drugs.
14. Describe the nurse’s role in the pharmacologic management of
inflammation and fever.
15. For each of the classes shown in the chapter outline, identify the prototype
and representative drugs and explain the mechanism(s) of drug action, primary
indications, contraindications, significant drug interactions, pregnancy
category, and important adverse effects.
16. Apply the nursing process to care for patients who are receiving drug
therapy for fever or inflammation
17. Compare and contrast the therapeutic applications of the two classes of
immunomodulators.
18. Describe the roles of interferons, interleukins, and other cytokines in
modulating the immune response.
19. Explain how pegylation of the interferon molecule allows for less frequent
dosing.
20. Explain why therapy with immunosuppressant medications is necessary
following organ transplants.
21. Identify the classes of drugs used as immunosuppressants.
22. Compare and contrast polyclonal and monoclonal antibodies.
23.For each of the classes shown in the chapter outline, identify the prototype
and representative drugs and explain the mechanism(s) of drug action, primary
indications, contraindications, significant drug interactions, pregnancy
category, and important adverse effects.
24.Apply the nursing process to care for patients who are receiving
immunostimulants and immunosuppressants.
25. Explain why the development of a smallpox vaccine was one of the most
significant discoveries of modern medicine.
26. Compare and contrast active and passive immunity.
27. Explain the immune response that leads to the development of active
immunity.
28. Prepare a table listing the types of vaccines, their indications, and potential
adverse effects.
29. Explain why it is important to administer childhood vaccines at specific
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NURSING DEPARTMENT
TOPIC (S)
LEARNING
ACTIVITIES
OUTSIDE
WORK &
ASSIGNED
READINGS
ages.
30. Identify contraindications for vaccine administration.
31. Describe the pathogenesis and immunization of bacterial infections,
including diphtheria, pertussis, tetanus, pneumococcus, and
meningococcus.
32. Describe the pathogenesis and immunization of viral infections, including
hepatitis A and B, influenza, rabies, measles, mumps, rubella, polio,
varicella zoster, human papillomavirus, and rotavirus.
33. Explain the rationale for administering antibodies to establish passive
immunity.
34. For each of the major vaccines and patient age groups, identify the
schedule for the recommended dosage sequence established by the Centers for
Disease Control and Prevention.
35. Apply the nursing process to care for patients receiving immunizing
agents.
36. Identify the structure and functions of the skin and associated structures.
37. Explain the process by which superficial skin cells are replaced.
38. Explain how skin diseases are classified.
39. Describe the drug therapies for bacterial, fungal, viral, and parasitic
infections of the skin.
40. Explain the etiology, pathogenesis, and pharmacotherapy for acne vulgaris,
rosacea, dermatitis, and psoriasis.
41. Outline the stepwise approach to treating psoriasis.
42. Describe the prevention and management of minor burns.
43. Explain the pharmacotherapy of alopecia.
44. Describe the nurse’s role in the pharmacologic management of skin
disorders.
45. For each of the classes shown in the chapter outline, identify the prototype
and representative drugs and explain the mechanism(s) of drug action,
primary indications, contraindications, significant drug interactions,
pregnancy category, and important adverse effects.
46. Apply the nursing process to the care of patients who are receiving
pharmacotherapy for skin disorders.
Pharmacotherapy of Inflammation and Fever
Review of Body Defenses and the Immune System
Immunostimulants and Immunosuppressants
Immunizing Agents
Pharmacotherapy of Dermatologic Disorders
Chapter readings
Discussion post
Quiz covering : Chapters 43,44,45,46 and 76
Cardiovascular Disorders
Read: (Ch 31,32,33,37,38)
Case Study
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NURSING DEPARTMENT
DATE
WEEK 6
At the end of this lesson, you will be able to:
SPECIFIC
1. Describe the major structures of the cardiovascular system.
OBJECTIVES
2. Identify the components of blood and their functions.
3. Construct a flowchart diagramming the primary steps of hemostasis.
4. Describe the structure of the heart and the function of the myocardium.
5. Describe the role of coronary arteries in supplying the myocardium
with oxygen.
6. Illustrate the flow of electrical impulses through the normal heart.
7. Explain the major factors affecting cardiac output.
8. Explain the effects of cardiac output, peripheral resistance, and blood
volume on hemodynamics.
9. Discuss how the vasomotor center, baroreceptors, chemoreceptors, and
hormones regulate blood pressure.
10. Summarize the link between high blood cholesterol, low-density
lipoprotein levels, and atherosclerosis.
11. Compare and contrast the different types of lipids.
12. Illustrate how lipids are transported through the blood.
13. Compare and contrast the clinical importance of the different types of
lipoproteins.
14. Give examples of how cholesterol and low-density lipoprotein levels
can be controlled with nonpharmacologic means.
15. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
16. Categorize antihyperlipidemic drugs based on their classification and
mechanism of action.
17. Explain the nurse’s role in the safe administration of drugs for lipid
disorders.
18. Apply the nursing process to care for patients receiving drug therapy
for lipid disorders.
19. Describe the role of calcium ions in the contraction of smooth and
cardiac muscle.
20. Explain why the actions of the beta1-adrenergic antagonists are similar
to those of the calcium channel blockers.
21. Describe how calcium channel blockers interact with the L-type
calcium channel.
22. Identify the physiological effects of calcium channel blockers on
arterial smooth muscle and cardiac muscle.
23. Explain the classification of calcium channel blockers.
24. Compare and contrast the actions of dihydropyridine versus
nondihydropyridine calcium channel blockers.
25. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
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NURSING DEPARTMENT
TOPIC (S)
LEARNING
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
26. Apply the nursing process to care for patients receiving calcium
channel blockers.
27. Explain how hypertension is classified.
28. Summarize the long-term consequences of untreated hypertension.
29. Compare and contrast the roles of nonpharmacologic and
pharmacologic methods in the management of hypertension.
30. Describe general principles guiding the pharmacotherapy of
hypertension.
31. Identify drug classes used in the primary and alternate management of
hypertension.
32. Describe the pharmacologic management of hypertensive emergencies.
33. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
34. Apply the nursing process to care for patients receiving
antihypertensive drugs.
35. Describe factors that affect myocardial oxygen supply and demand.
36. Explain the relationship between atherosclerosis and coronary artery
disease.
37. Explain the pathophysiology of angina pectoris and myocardial
infarction.
38. Discuss the role of therapeutic lifestyle changes in the management of
coronary artery disease.
39. Describe the pharmacologic management of the different types of
angina.
Describe the pharmacologic management of myocardial infarction
40. Discuss the role of therapeutic lifestyle changes in the management of
coronary artery disease.
41. Describe the pharmacologic management of the different types of
angina.
42. Describe the pharmacologic management of myocardial infarction.
43. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
44. Apply the nursing process to care for patients receiving drug therapy
for angina and myocardial infarction
Review of the Cardiovascular System
Pharmacotherapy of Hyperlipidemia
Calcium Channel Blockers
Pharmacotherapy of Hypertension
Pharmacotherapy of Angina Pectoris and Myocardial Infarction
Chapter readings
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ACTIVITIES
OUTSIDE
WORK &
ASSIGNED
READINGS
Discussion post
Case Study
Quiz covering: Chapters 31,32,33,37,38
Read: Cardiovascular Disorders (39,40,41)
Read: Respiratory Disorders (Ch 47,48)
Case Study
DATE
WEEK 7
At the end of this week, the students will be able to:
SPECIFIC
18. Identify the major diseases associated with heart failure.
OBJECTIVES
19. Relate how the symptoms associated with heart failure may be caused
by weakened heart muscle and diminished cardiac output.
20. Identify compensatory mechanisms used by the body to maintain
cardiac output in patients with heart failure.
21. Describe how heart failure is classified.
22. Describe the nurse’s role in the pharmacologic management of heart
failure.
23. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
24. Apply the nursing process to care for patients receiving drug therapy
for heart failure.
25. Identify disorders associated with an increased risk of dysrhythmias.
26. Explain how rhythm abnormalities can affect cardiac function.
27. Sketch a typical cardiac action potential and label the flow of
potassium, sodium, and calcium ions during each phase.
28. Design a table that indicates the classification of dysrhythmias and the
types of drugs used to treat them.
29. Describe general principles guiding the management of dysrhythmias.
30. Identify the primary mechanisms of action of antidysrhythmic drugs
31. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
32. Apply the nursing process to care for patients receiving drug therapy
for dysrhythmias.
16. Describe primary risk factors for thromboembolic disorders.
17. Explain the etiology and symptoms of coagulation disorders.
18. Identify the primary mechanisms by which coagulation-modifying
drugs act.
19. Explain how laboratory testing of coagulation parameters is used to
monitor anticoagulant pharmacotherapy.
20. Describe the nurse’s role in the pharmacologic management of patients
with coagulation disorders
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TOPIC (S)
21. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, Pregnancy category, and important adverse effects.
22. Apply the nursing process to care for patients receiving drug therapy
for coagulation disorders.
23. Identify the anatomic structures associated with the lower respiratory
tract and their functions.
24. Explain how the autonomic nervous system regulates airway diameter.
25. Explain the role of inflammation and bronchospasm in the
pathogenesis of asthma.
26. Compare the advantages and disadvantages of using the inhalation
route of drug administration for pulmonary drugs.
27. Describe the types of devices used to deliver aerosol therapies via the
inhalation route.
28. Explain the three basic principles of asthma management
recommended by the National Asthma Education and Prevention Program.
29.Compare and contrast the indications for pharmacotherapy with the
short- versus long-acting beta-adrenergic agonists.
30. Describe the nurse’s role in the pharmacologic management of lower
respiratory tract disorders
31. Apply the nursing process to care for patients receiving
pharmacotherapy for lower respiratory tract disorders
32. Identify structures of the upper respiratory tract that serve as body
defenses against foreign substances.
33. Describe the common causes and symptoms of allergic rhinitis.
34. Differentiate between H1 and H2 histamine receptors.
35. Compare and contrast the first- and second-generation antihistamines.
36. Explain why intranasal corticosteroids are the drugs of choice for the
treatment of allergic rhinitis.
37. Compare and contrast the oral and intranasal decongestants.
38. Explain why it is usually better to take individual drugs for the common
cold, rather than a multisymptom combination product.
39. Describe the appropriate use of cough suppressants.
40. Describe the use of drugs prescribed to treat thick bronchial secretions.
41. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of drug
action, primary indications, contraindications, significant drug interactions,
pregnancy category, and important adverse effects.
42. Apply the nursing process to care for patients who are receiving
pharmacotherapy for allergic rhinitis and the common cold.
Pharmacotherapy of Heart Failure
Pharmacotherapy of Dysrhythmias
Pharmacotherapy of Coagulation Disorders
Pharmacotherapy of Asthma and Other Pulmonary Disorders
Pharmacotherapy of Allergic Rhinitis and the Common Cold
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LEARNING
ACTIVITIES
Discussion post
Case study
Quiz covering : Cardiovascular Disorders (39,40,41)
Read: Respiratory Disorders (Ch 47,48)
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
SPECIFIC
OBJECTIVES
Gastrointestinal Disorders
Read: (Ch 61,62,63,64)
Prepare for Mid-term
WEEK 8
At the end of this lesson, you will be able to:
1. 1. Describe the major anatomic structures of the digestive system.
2. Outline the steps in the process of digestion.
3. Describe the primary functions of the stomach.
4. Analyze how the anatomic structures of the small intestine promote the
absorption of nutrients and drugs
5. Describe the primary structures and functions of the large intestine.
6. Describe the functions of the liver and their relevance to drug therapy.
7. Explain the hepatic portal system and its importance to drug therapy.
8. Explain the nervous control of digestion.
9. Explain the enzymatic breakdown of nutrients by the digestive system.
10. Explain the physiological regulation of gastric acid secretion.
11. Describe factors that suppress and those that promote the formation of
peptic ulcers.
12. Compare and contrast duodenal ulcers and gastric ulcers.
13. Identify the etiology, signs, and symptoms of peptic ulcer disease and
gastroesophageal reflux disease.
14. Outline the treatment goals for the pharmacotherapy of peptic ulcer
disease and gastroesophageal reflux disease.
15. Identify the classification of drugs used to treat peptic ulcer disease and
gastroesophageal reflux disease.
16. Explain the pharmacologic strategies for eradicating Helicobacter
pylori.
17. Describe the nurse’s role in the pharmacologic management of patients
with peptic ulcer disease and gastroesophageal reflux disease.
18. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
19. Apply the nursing process to care for patients who are receiving
pharmacotherapy for peptic ulcer disease and gastroesophageal reflux
disease.
20. Compare and contrast the definition of constipation used by patients to
that used for diagnosis by health care providers.
21. Compare and contrast the different mechanisms of action of laxatives.
22. Explain the pathogenesis of constipation and diarrhea.
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23. Compare and contrast the types of drugs used to treat inflammatory
bowel disease and irritable bowel syndrome.
24. Explain conditions in which the pharmacotherapy of nausea and
vomiting is indicated.
25. Identify drugs that are used to treat acute and chronic pancreatitis.
26. Describe the nurse’s role in the pharmacologic management of bowel
disorders, nausea and vomiting, and other gastrointestinal conditions
27. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of drug
action, primary indications, contraindications, significant drug interactions,
pregnancy category, and important adverse effects.
28. Apply the nursing process to care for patients who are receiving
pharmacotherapy for bowel disorders, nausea and vomiting, and other
gastrointestinal conditions.
29. Describe the role of vitamins in maintaining wellness.
30. Identify conditions for which vitamin and mineral therapy may be
indicated.
31. Explain the governmental regulation of vitamins and minerals.
32. Discuss the role of the recommended dietary allowance in determining
the standardized requirement of various vitamins and minerals.
33. Compare and contrast fat-soluble and water-soluble vitamins.
34. For each of the major vitamins, identify the mechanism(s) of action,
primary indications, contraindications, significant drug interactions, pregnancy
category, and important adverse effects.
35. Identify the major functions of macrominerals and microminerals.
36. Apply the nursing process to care for patients who are receiving
vitamin and mineral supplementation therapy.
Review of the Gastrointestinal System
TOPIC (S)
Pharmacotherapy of Peptic Ulcer Disease
Pharmacotherapy of Bowel Disorders and Other Gastrointestinal Conditions
Vitamins and Minerals
LEARNING Chapter readings
ACTIVITIES Discussion post
Case Study
Midterm exam covering weeks 1-8
Read: Gastrointestinal Disorders (65,66)
OUTSIDE
Read: Genitourinary (Ch 35, 53)
WORK &
Case Study
ASSIGNED
Quiz
READINGS
DATE
Week 9
At the end of this lesson, you will be able to:
SPECIFIC
1. Identify conditions that may benefit from parenteral or enteral
OBJECTIVES
nutrition.
2. Compare and contrast enteral and parenteral methods of nutrition.
3. Compare and contrast methods by which enteral feedings are
administered.
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4. Distinguish among polymeric, elemental, semielemental, and modular
formulas for enteral nutrition.
5. Identify the basic classes of nutrients contained in enteral formulas and
their functions.
6. Identify the possible complications and adverse effects of enteral
nutrition administration.
7. Describe the types of drug interactions that can occur when enteral
nutrition formulas are given.
8. Explain the differences between delivering parenteral nutrition through
a peripheral line versus a central line
9. Describe the components of total parenteral nutrition solutions and the
function of each element in attaining the body’s daily requirements.
10. Describe the possible complications of parenteral nutrition therapy.
11. Identify drugs that may be incompatible with parenteral nutrition
solutions.
12. Apply the nursing process to care for patients who are receiving enteral
or parenteral nutrition.
13. Explain the role of the urinary system in maintaining fluid, electrolyte,
and acid–base homeostasis.
14. Explain the physiological processes that change the composition of
filtrate as it travels through the nephrons.
15. Describe the adjustments in pharmacotherapy that must be considered
in patients with renal failure.
16. Identify indications for diuretics.
17. Compare and contrast the loop, thiazide, potassium-sparing, osmotic,
and carbonic anhydrase inhibitor diuretics.
18. Describe the nurse’s role in the pharmacologic management of renal
failure and in diuretic therapy.
19. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
20. Use the nursing process to care for patients who are receiving diuretics
or drug therapy for renal failure.
24. Classify types of urinary tract infections based on their anatomic
location.
25. Explain the epidemiology and pathogenesis of urinary tract infections.
26. Compare and contrast the pharmacotherapy of complicated versus
uncomplicated urinary tract infections.
27. Identify the classes of antibiotics used to treat urinary tract infections.
28. Describe modifications in the pharmacotherapy of urinary tract
infections for infants and children, pregnancy, older adults, and those with
recurring infections.
29. Explain why folate inhibitors exert selective toxicity toward bacterial
cells.
30. For each of the classes shown in the chapter outline, identify the
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TOPIC (S)
LEARNING
ACTIVITIES
prototype and representative drugs and explain the mechanism(s) of drug
action, primary indications, contraindications, significant drug interactions,
pregnancy category, and important adverse effects.
31.Apply the nursing process to care for patients receiving
pharmacotherapy for urinary tract infections.
Enteral and Parenteral Nutrition
Weight Reduction Strategies and the Pharmacotherapy of Obesity
Diuretic Therapy and the Pharmacotherapy of Renal Failure
Sulfonamides and the Pharmacotherapy of Urinary Tract Infections
Chapter readings
Discussion post
Quiz covering: Gastrointestinal Disorders (65,66) and
Genitourinary (Ch 35, 53)
Read: Endocrine Disorders Chapters 34, 35, 67, 68, 69
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
WEEK 10
At the end of this lesson, you will be able to:
SPECIFIC
1. Illustrate the steps in the renin-angiotensin-aldosterone pathway.
OBJECTIVES
2. Identify the primary physiological factors that control renin secretion.
3. Explain the two primary functions of angiotensin-converting enzyme.
4. Describe multiple mechanisms by which angiotensin II raises blood
pressure.
5. Explain how the actions of aldosterone can lead to high blood pressure.
6. Identify the specific steps in the renin-angiotensin-aldosterone system
that can be blocked by medications.
7. Explain how the actions of aldosterone can lead to high blood pressure.
8. Identify the specific steps in the renin-angiotensin-aldosterone system
that can be blocked by medications.
9. Apply the nursing process to care for patients receiving drugs affecting
the renin-angiotensin-aldosterone system.
10. Explain the role of the urinary system in maintaining fluid, electrolyte,
and acid–base homeostasis.
11. Explain the physiological processes that change the composition of
filtrate as it travels through the nephrons.
12. Describe the adjustments in pharmacotherapy that must be considered
in patients with renal failure.
13. Identify indications for diuretics.
14. Compare and contrast the loop, thiazide, potassium-sparing, osmotic,
and carbonic anhydrase inhibitor diuretics.
15. Describe the nurse’s role in the pharmacologic management of renal
failure and in diuretic therapy.
16. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of drug
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action, primary indications, contraindications, significant drug interactions,
pregnancy category, and important adverse effects.
17. Use the nursing process to care for patients who are receiving diuretics
or drug therapy for renal failure.
18. Describe the general structure and functions of the endocrine system.
19. Compare and contrast the nervous and endocrine systems in the control
of homeostasis.
20. Explain circumstances in which hormone receptors may be upregulated or down-regulated.
21. Through the use of a specific example, explain the concept of negative
feedback in the endocrine system.
22. Explain the three primary types of stimuli that regulate hormone
secretion.
23. Identify indications for hormone pharmacotherapy.
24. Explain the principal actions of the hormones secreted by the
hypothalamus and pituitary gland.
25. Identify indications for hypothalamic hormone therapy.
26. Explain the pharmacotherapy of growth hormone disorders in children
and adults.
27. Explain the pharmacotherapy of antidiuretic hormone disorders.
28. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
29. Apply the nursing process to care for patients receiving
pharmacotherapy for disorders of the hypothalamus and pituitary
gland.
30. Explain how blood glucose levels are maintained within narrow limits
by insulin and glucagon.
31. Compare and contrast the etiology and pathogenesis of type 1, type 2,
and gestational diabetes.
32. Describe the signs and diagnosis of diabetes.
33. Describe the acute complications of diabetes.
34. Identify the chronic complications of diabetes.
35. Compare and contrast the pharmacotherapy of the different types of
diabetes.
36. For each type of insulin, identify the onset of action, peak action and
duration of action, administration routes, when it is given related to
meals, compatibility with other insulins, and adverse effects.
37. Apply the nursing process to care for patients who are receiving
pharmacotherapy for diabetes.
38. Explain how blood glucose levels are maintained within narrow limits
by insulin and glucagon.
39. Compare and contrast the etiology and pathogenesis of type 1, type 2,
and gestational diabetes.
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TOPIC (S)
LEARNING
ACTIVITIES
OUTSIDE
WORK &
ASSIGNED
READINGS
40. Describe the signs and diagnosis of diabetes.
41. Describe the acute complications of diabetes.
42. Identify the chronic complications of diabetes.
43. Compare and contrast the pharmacotherapy of the different types of
diabetes.
44. Describe the acute complications of diabetes.
45. Identify the chronic complications of diabetes.
46. Compare and contrast the pharmacotherapy of the different types of
diabetes.
47. Describe the acute complications of diabetes.
48. Identify the chronic complications of diabetes.
49. Compare and contrast the pharmacotherapy of the different types of
diabetes.
Drugs Affecting the Renin-Angiotensin-Aldosterone System
Diuretic Therapy and the Pharmacotherapy of Renal Failure
Review of the Endocrine System
Hypothalamic and Pituitary Drugs
Pharmacotherapy of Diabetes Mellitus
Chapter readings
Discussion post
Quiz covering: Endocrine Disorders Chapters 34, 35, 67, 68, 69
Read: Endocrine Disorders (70,71)
Read: Musculoskeletal Disorders (Ch 27, 75)
Case Study
DATE
WEEK 11
At the end of this lesson, you will be able to:
SPECIFIC
1. 1. Explain the functions of thyroid hormone.
OBJECTIVES
2. Explain the negative feedback control of thyroid function.
3. Explain how thyroid disorders are diagnosed.
4. Describe the pathophysiology of thyroid disorders.
5. Describe the pharmacotherapy of thyroid disorders.
6. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
7. drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
8. Apply the nursing process to the care of patients receiving
pharmacotherapy for thyroid disorders.
9. Apply the nursing process to the care of patients receiving
pharmacotherapy for thyroid disorders.
10. Identify the functions of the three classes of hormones secreted by the
adrenal gland.
11. Diagram the negative feedback regulation of corticosteroid secretion.
12. Identify common properties of the corticosteroid medications.
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TOPIC (S)
LEARNING
ACTIVITIES
OUTSIDE
13. Describe the potential adverse effects of long-term corticosteroid
therapy.
14. Compare and contrast the pharmacotherapy of acute and chronic
adrenocortical insufficiency.
15. Explain how corticosteroids affect the inflammatory and immune
responses.
16. Recognize nonendocrine disorders that respond to corticosteroid
therapy.
17. Describe indications for pharmacotherapy with mineralocorticoids.
18. Explain the pharmacotherapy of Cushing’s syndrome.
19. Describe the nurse’s role in the pharmacologic management of adrenal
disorders.
20. Apply the nursing process to the care of patients who are receiving
pharmacotherapy with corticosteroids and mineralocorticoids.
21. Compare and contrast the etiology and pathophysiology of muscle
spasms and muscle spasticity.
22. Describe the nonpharmacologic management of muscle spasms and
muscle spasticity.
23. Identify drug classes used to treat muscle spasms and spasticity.
24. Compare and contrast the actions of the centrally acting and directacting skeletal muscle relaxants.
25. Explain the role of skeletal muscle relaxants as surgical adjuncts.
26. Describe the nurse’s role in the pharmacologic management of muscle
spasms and muscle spasticity.
27. Apply the nursing process to care for patients receiving
pharmacotherapy for muscle spasms and spasticity.
28. Describe the role of calcium in maintaining homeostasis in the
nervous, muscular, skeletal, and cardiovascular systems.
29. Identify the recommended dietary allowance and the normal serum
levels of calcium.
30. Explain the roles of parathyroid hormone, calcitonin, and vitamin D in
maintaining calcium balance.
31. Explain the etiology, pathogenesis, and pharmacotherapy for
hypocalcemia, osteomalacia, osteoporosis, rickets, osteoarthritis,
rheumatoid arthritis, and gout.
Pharmacotherapy of Thyroid Disorders
Corticosteroids and Drugs Affecting the Adrenal Cortex
Pharmacotherapy of Muscle Spasms and Spasticity
Pharmacotherapy of Bone and Joint Disorders
Chapter readings
Discussion post
Case Study
Quiz covering: Endocrine Disorders (70,71) and
Musculoskeletal Disorders (Ch 27, 75)
Read: Neurological (Ch 16, 17, 18, 19, 20)
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WORK &
ASSIGNED
READINGS
DATE
SPECIFIC
OBJECTIVES
Case Study
Review the Pharmacology of the Central Nervous
WEEK 12
At the end of this lesson, you will be able to:
1. Distinguish between the functions of the central and peripheral nervous
systems.
2. Compare and contrast the two divisions of the peripheral nervous
system.
3. Compare and contrast the actions of the sympathetic and
parasympathetic divisions of the autonomic nervous system.
4. Explain the process of synaptic transmission.
5. Explain mechanisms by which drugs affect synaptic transmission.
6. Describe the actions of acetylcholine at cholinergic synapses.
7. Describe the actions of norepineprhine at adrenergic synapses.
8. Compare the actions of the adrenal medulla with those of other
sympathetic effector organs.
9. Explain how higher centers in the brain can influence autonomic
function.
10. Design a method for classifying autonomic drugs based on which
receptors are affected.
11. Identify the physiological responses produced when a drug activates
cholinergic receptors.
12. Compare and contrast the mechanisms of action for direct- and
indirect-acting cholinergic agonists.
13. Differentiate among the following types of cholinergic drugs: direct
muscarinic agonists, indirect muscarinic agonists, and nicotinic
agonists.
14. Differentiate between the pharmacotherapy of cholinergic crisis and
myasthenic crisis.
15. Describe the pharmacotherapy of myasthenia gravis.
16. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
17. Apply the nursing process to care for patients receiving drug therapy
with cholinergic agonists.
18. Identify the physiological responses produced when a drug activates
adrenergic receptors.
19. Explain the direct and indirect mechanisms by which adrenergic
agonists act.
20. Compare and contrast the characteristics of catecholamines and
noncatecholamines.
21. Identify indications for pharmacotherapy with adrenergic agonists.
22. Compare and contrast the types of responses that occur when a drug
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TOPIC (S)
LEARNING
ACTIVITIES
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
SPECIFIC
OBJECTIVES
activates alpha1-, alpha2-, beta1-, or beta2-adrenergic receptors.
23. Apply the nursing process to care for patients receiving drug therapy
with adrenergic agonists.
24. Identify the physiological responses produced when a drug blocks
adrenergic receptors.
25. Compare and contrast the types of physiological responses that occur
when a drug blocks alpha1-, alpha2-, beta1-, and beta2-adrenergic
receptors.
26. Identify indications for pharmacotherapy with adrenergic antagonists.
27. Describe the first-dose phenomenon and how it may be prevented.
28. Explain the advantages of selective beta antagonists versus
nonselective beta antagonists.
29. Explain why beta-adrenergic antagonists should never be abruptly
discontinued.
Review of Neurotransmitters and the Autonomic Nervous System
Cholinergic Agonists
Andrenergic Agonists
Andrenergic Antagonists
Cholinergic Antagonists
Chapter readings
Discussion post
Quiz covering: Neurological (Ch 16, 17, 18, 19, 20)
Read: Hematological Disorders (Ch 42,43,44,45,46)
WEEK 12
At the end of this lesson, you will be able to:
1. Distinguish between the functions of the central and peripheral nervous
systems.
2. Compare and contrast the two divisions of the peripheral nervous
system.
3. Compare and contrast the actions of the sympathetic and
parasympathetic divisions of the autonomic nervous system.
4. Explain the process of synaptic transmission.
5. Explain mechanisms by which drugs affect synaptic transmission.
6. Describe the actions of acetylcholine at cholinergic synapses.
7. Describe the actions of norepineprhine at adrenergic synapses.
8. Compare the actions of the adrenal medulla with those of other
sympathetic effector organs.
9. Explain how higher centers in the brain can influence autonomic
function.
10. Design a method for classifying autonomic drugs based on which
receptors are affected.
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TOPIC (S)
LEARNING
ACTIVITIES
11. Identify the physiological responses produced when a drug activates
cholinergic receptors.
12. Compare and contrast the mechanisms of action for direct- and
indirect-acting cholinergic agonists.
13. Differentiate among the following types of cholinergic drugs: direct
muscarinic agonists, indirect muscarinic agonists, and nicotinic
agonists.
14. Differentiate between the pharmacotherapy of cholinergic crisis and
myasthenic crisis.
15. Describe the pharmacotherapy of myasthenia gravis.
16. For each of the classes shown in the chapter outline, identify the
prototype and representative drugs and explain the mechanism(s) of
drug action, primary indications, contraindications, significant drug
interactions, pregnancy category, and important adverse effects.
17. Apply the nursing process to care for patients receiving drug therapy
with cholinergic agonists.
18. Identify the physiological responses produced when a drug activates
adrenergic receptors.
19. Explain the direct and indirect mechanisms by which adrenergic
agonists act.
20. Compare and contrast the characteristics of catecholamines and
noncatecholamines.
21. Identify indications for pharmacotherapy with adrenergic agonists.
22. Compare and contrast the types of responses that occur when a drug
activates alpha1-, alpha2-, beta1-, or beta2-adrenergic receptors.
23. Apply the nursing process to care for patients receiving drug therapy
with adrenergic agonists.
24. Identify the physiological responses produced when a drug blocks
adrenergic receptors.
25. Compare and contrast the types of physiological responses that occur
when a drug blocks alpha1-, alpha2-, beta1-, and beta2-adrenergic
receptors.
26. Identify indications for pharmacotherapy with adrenergic antagonists.
27. Describe the first-dose phenomenon and how it may be prevented.
28. Explain the advantages of selective beta antagonists versus
nonselective beta antagonists.
29. Explain why beta-adrenergic antagonists should never be abruptly
discontinued.
Review of Neurotransmitters and the Autonomic Nervous System
Cholinergic Agonists
Andrenergic Agonists
Andrenergic Antagonists
Cholinergic Antagonists
Chapter readings
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Discussion post
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
SPECIFIC
OBJECTIVES
Quiz covering: Hematological Disorders (Ch 42,43,44,45,46)
Read: Hematological Disorders (Ch 42,43,44,45,46)
WEEK 13
At the end of the week, the student will be able to:
1. Describe the physiology of hematopoiesis.
2. Describe how aspects of hematopoiesis can be modified by the
administration of pharmacologic agents.
3. Explain the functions of erythropoietin.
4. Explain the functions of colony-stimulating factors.
5. Classify types of anemia based on their causes.
6. Illustrate the metabolism, storage, and transfer of iron in the body.
7. Identify the role of intrinsic factor in the absorption of vitamin B12.
8. Compare and contrast anemias caused by vitamin B12 and folate
deficiency.
9. Describe the nurse’s role in the pharmacologic management of
hematopoietic disorders.
10. Apply the nursing process to care for patients who are receiving drug
therapy for hematopoietic disorders.
11. Identify the major components of the lymphatic system.
12. Describe the components of the nonspecific body defense system and
their functions.
13. Compare and contrast specific and nonspecific body defenses.
14. Identify the signs and symptoms of inflammation.
15. Outline the basic steps in the acute inflammatory response.
16. Explain the role of histamine and other chemical mediators in the
inflammatory response.
17. Compare and contrast the humoral and cell-mediated immune
responses
18. Explain the pathophysiology of inflammation and fever.
19. Identify drug classes used to treat inflammation and fever.
20. Explain how aspirin damages the gastrointestinal mucosa.
21. Describe the symptoms and treatment of salicylism.
22. Compare the actions and adverse effects of aspirin to ibuprofen and
ibuprofen-like drugs.
23. Compare the actions and adverse effects of the cyclooxygenase-2
inhibitors to other nonsteroidal anti-inflammatory drugs.
24. Describe the nurse’s role in the pharmacologic management of
inflammation and fever.
25. Apply the nursing process to care for patients who are receiving drug
therapy for fever or inflammation.
26. Compare and contrast the therapeutic applications of the two classes of
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immunomodulators.
27. Describe the roles of interferons, interleukins, and other cytokines in
modulating the immune response.
28. Explain how pegylation of the interferon molecule allows for less
frequent dosing.
29. Explain why therapy with immunosuppressant medications is
necessary following organ transplants.
30. Identify the classes of drugs used as immunosuppressants.
31. Compare and contrast polyclonal and monoclonal antibodies.
32. Apply the nursing process to care for patients who are receiving
immunostimulants and immunosuppressants.
33. Explain why the development of a smallpox vaccine was one of the
most significant discoveries of modern medicine.
34. Compare and contrast active and passive immunity.
35. Explain the immune response that leads to the development of active
immunity.
36. Explain why the development of a smallpox vaccine was one of the
most significant discoveries of modern medicine.
37. Compare and contrast active and passive immunity.
38. Explain the immune response that leads to the development of active
immunity.
39. Explain why the development of a smallpox vaccine was one of the
most significant discoveries of modern medicine.
40. Compare and contrast active and passive immunity.
41. Explain the immune response that leads to the development of active
immunity.
42. Explain why the development of a smallpox vaccine was one of the
most significant discoveries of modern medicine.
43. Compare and contrast active and passive immunity.
44. Explain the immune response that leads to the development of active
immunity.
45. Explain why the development of a smallpox vaccine was one of the
most significant discoveries of modern medicine.
46. Compare and contrast active and passive immunity.
47. Explain the immune response that leads to the development of active
immunity.
48. Explain why the development of a smallpox vaccine was one of the
most significant discoveries of modern medicine.
49. Compare and contrast active and passive immunity.
50. Explain the immune response that leads to the development of active
immunity.
51. Explain why the development of a smallpox vaccine was one of the
most significant discoveries of modern medicine.
52. Compare and contrast active and passive immunity.
53. Explain the immune response that leads to the development of active
immunity.
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TOPIC (S)
LEARNING
ACTIVITIES
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
SPECIFIC
OBJECTIVES
54. Describe the pathogenesis and immunization of viral infections,
including hepatitis A and B, influenza, rabies, measles, mumps,
rubella, polio, varicella zoster, human papillomavirus, and rotavirus.
55. Explain the rationale for administering antibodies to establish passive
immunity.
56. For each of the major vaccines and patient age groups, identify the
schedule for the recommended dosage sequence established by the
Centers for Disease Control and Prevention.
57. Apply the nursing process to care for patients receiving immunizing
agents.
Pharmacotherapy of Hematopoietic Disorders
Review of Body Defenses and the Immune System
Pharmacotherapy of Inflammation and Fever
Immunostimulants and Immunosuppressants
Immunizing Agents
Chapter readings
Discussion post
Quiz covering: Hematological Disorders (Ch 42,43,44,45,46)
Read: Reproductive Disorders (Chapter 10,72, 73, 74)
WEEK 14
At the end of this lesson, the student will be able to:
1. Justify the rationale for using drugs during pregnancy and lactation.
2. Describe physiological changes during pregnancy that may affect the
absorption, distribution, metabolism, and excretion of drugs.
3. Describe the placental transfer of drugs from mother to infant.
4. Differentiate among the U.S. Food and Drug Administration pregnancy
risk categories.
5. Explain how drugs administered during the different stages of fetal
development affect the potential for teratogenic effects.
6. Identify factors that influence the transfer of drugs into breast milk.
7. Describe signs of adverse drug reactions in the breast-feeding infant.
8. Outline important points in the patient and family education regarding
drug use during pregnancy and lactation
9. Describe signs of adverse drug reactions in the breast-feeding infant.
10. Outline important points in the patient and family education regarding
drug use during pregnancy and lactation
11. Compare and contrast the advantages and disadvantages of hormone
replacement therapy during menopause.
12. Explain the use of uterine stimulants to promote labor and delivery.
13. Discuss the use of uterine relaxants in suppressing preterm labor.
14. Explain how drug therapy may be used to treat female infertility.
15. Describe the nurse’s role in the pharmacologic management of
disorders and conditions of the female reproductive system.
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TOPIC (S)
LEARNING
ACTIVITIES
OUTSIDE
WORK &
ASSIGNED
READINGS
DATE
TOPIC (S)
16. Apply the nursing process to the care of patients who are receiving
pharmacotherapy for disorders and conditions of the female
reproductive system.
17. Identify the choices available for birth control.
18. Delineate advantages and disadvantages of the different contraceptive
options.
19. Explain the mechanisms by which estrogens and progestins prevent
conception.
20. Compare the safety and effectiveness of different birth control
methods.
21. Explain how drugs may be used to provide emergency contraception
and to terminate pregnancy.
22. Describe the nurse’s role in the pharmacologic management of patients
who are taking oral contraceptives.
23. Compare and contrast the options available for long-term
contraception.
24. Explain the use of drugs for emergency contraception and inducing
pharmacologic abortion.
25. Apply the nursing process to the care of patients who are receiving
pharmacotherapy for contraception
Pharmacotherapy During Pregnancy and Lactation
Estrogens, Progestins, and Drugs Modifying Uterine Function
Drugs for Modifying Conception
Drugs for Disorders and Conditions of the Male Reproductive System
Chapter readings
Discussion post
Quiz covering: (Chapter 10,72, 73, 74)
Prepare for final exam covering weeks 9-14
WEEK 15
Final Exam
Instructional Methods
The following strategies may be used in this class:
1. Threaded Discussions
2. Case studies
3. Quizzes
4. Readings
5. Exams
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Academic Honesty: When learners fail to complete their own work, they are cheating
themselves out of their education and are committing plagiarism. Plagiarism, or failing to meet
the academic honesty policy, will result in disciplinary actions by the institution.
Plagiarism is dishonest behavior that will not be tolerated. A student will not receive credit if
found to have plagiarized his/her work and may result in suspension or dismissal from the
school. Follow the link for examples of
plagiarism: http://examples.yourdictionary.com/examples/examples-of-plagiarism.html
APA Format: All of your writing must be done following APA format. For more information
regarding this format, go to Purdue Owl or follow this
link:https://owl.english.purdue.edu/owl/resource/560/01/
Late work & Educational Responsibility: All assignments must be completed by the last day
of the schedule unless an alternate due date has been previously approved by your instructor or
documentation has been provided regarding extreme circumstances. It is the learner's
responsibility to communicate with the instructor about extreme circumstances or ask questions
concerning the assignment and their due dates.
Threaded discussions: Students are to respond to the instructor’s weekly discussion post by
Wednesday at 1159 PM (EST). The responses must be substantial (at least 125 words in length
using correct grammar).
These are intended to stimulate discussion and re-enforce course content. The student must also
respond to two other student posts by Friday at 11:59 PM (EST). Please refer to the assignment
calendar for assignment due dates.
ASSESSMENT TESTING FOR NURSING PROGRAM REQUIREMENT:
As part of certain nursing courses, students are required to take third-party computerized
assessments, These assessments are intended to provide students with the tools they need to be
successful in the Nursing program and on the NCLEX; as well as. Increase confidence and
familiarity with computerized testing, The assessments typically include various types of
formats, including multiple choice items, multiple response items, fill-in-the-blank items, dragand drop items, hot spots items, chart/exhibit items, and other items,. The assessments help
identify deficit areas and provide students opportunities to practice and learn. Each assessment
can represent up to the percent (10%) of a student’s course grade. Failure to achieve the
minimum assessment score may result in a loss of points on an examination, or required
remediation or retesting (as outlined in the course syllabus). Students who do not successfully
complete the remediation or retest associated with an assessment examination (as outlined in the
course syllabus) may receive an incomplete in a course and may be required to repeat the course
in its entirety. An incomplete due to failure to successfully complete the assessment testing
remediation or successfully retest is considered a failure for the course.
Additional Resources
Web sites
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Assessment Criteria and Methods of Evaluating Students
90 – 100%
80 – 89%
75 – 79%
< 75%
A
B
C
F
Do not count on a curve!
Generally, the grades “A” through “C-” are considered passing grades. Grades "W" and "I" indicate that
no grades were earned for the course. A "W" grade indicates that the student withdrew from the course. An
"I" grade indicates that the student was passing the course, but failed to complete all the required course
work. The instructor, in his/her discretion may grant an "I" grade instead of an "F", pending completion of
the course work by the student within a specified time arranged by the instructor and told to the student. It
is the student's responsibility to follow-up with the instructor to complete the course work. If the course
work is not completed by the arranged time, the “I” grade becomes an “F".
Distribution of Grade Elements
Discussions
20%
Assignments/Homework:
(Case studies)
20%
Midterm
20%
Quizzes
20%
Final
20%
Total:
100 %
Revised: March 13, 2015
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