The Cell Cycle and Mitosis, Control of Cell Growth
Teacher Name: Ann Schultz
Classes and Grades Taught: Honors Biology for 9 th through 12 th grades, Regular Biology for 9 th through 12 th grades
Lesson Dates: January 9-13, 2012
Unit Topic: The Cell Cycle, Mitosis and Control f the Cell Growth
Unit Objectives: Explain how characteristics of living things are passed from generation to generation.
Previous Lesson Topic: Exploration of the cell cycle and mitosis
Current Lesson Topics: Reinforce knowledge of the cell cycle and mitosis; explore control of the cell cycle, DNA and chromosomal mutations, and uncontrolled cell growth; quiz on the cell cycle
Next Lesson Topic: Introduction to meiosis
Lesson Objectives
Students will be able to:
Explain that hereditary information is contained in genes, located in the chromosomes of each cell; that cells contain many thousands of different genes; that one or many genes can determine an inherited trait of an individual, and a single gene can influence more than one trait; and that before a cell divides, this genetic information must be copied and apportioned evenly into the daughter cells.
Standards Addressed:
B1.1D Identify patterns in data and relate them to theoretical models.
B1.2C Develop an understanding of a scientific concept by accessing information from multiple sources. Evaluate the scientific accuracy and significance of the information.
B1.2D Evaluate scientific explanations in a peer review process or discussion format.
B4.2B Recognize that every species has its own characteristic DNA sequence.
B4.3A Compare and contrast the processes of cell division (mitosis and meiosis), particularly as those processes relate to production of new cells and to passing on genetic information between generations.
Students will demonstrate accomplishment of objectives by:
Responding to Impromptu questions
TE894 – Spring 2012 1/7

The Cell Cycle and Mitosis, Control of Cell Growth
Completing cell cycle and mitosis activities
Completing cancer case study partner reading, reporting and answering class questions
Answering online Cook E-Question on www.edmodo.com
Completing quiz on the cell cycle
Focus Question: How does each daughter cell receive a complete set of chromosomes?
Objective: Explain how characteristics of living things are passed on from generation to generation.
Vocabulary
Centriole
Chromatid
Daughter cell
Homologous chromosomes
Spindle Fiber
Flashcards
1. Cell division
– definition
2. Three stages of cell division – name them (I, M, C)
3. Interphase – definition, including Gap 1 Phase, S Phase, Gap 2 Phase
4. S-Phase
– what happens during
5. Chromosomes – definition and drawing with centromere and sister chromatids labeled
6. Mitosis – definition
7. Phases of mitosis
– name them (P, M, A, T)
8. Prophase
– definition and drawing
9. Metaphase – definition and drawing
10. Anaphase – definition and drawing
11. Telophase
– definition and drawing
12. Cytokinesis – definition and drawing
Possible Class Activities:
Mitosis video (1 ½ minutes) http://www.teachersdomain.org/resource/tdc02.sci.life.stru.dnadivide/
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The Cell Cycle and Mitosis, Control of Cell Growth
Mitosis animation http://www.teachersdomain.org/asset/lsps07_int_celldivision/
Cell cycle review through pipe cleaner chromosome activity
Percentage of time cells spend in each phase of the cell cycle (interactive) http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/activity_description.html
How Cancer Cells Grow and Divide http://www.pbs.org/wgbh/nova/teachers/body/how-cancer-cells-grow-divide.html
Mitosis and meiosis exploration activity http://www.indiana.edu/~ensiweb/lessons/gen.mm.html
Understanding Cancer Teacher Guide: http://science.education.nih.gov/supplements/nih1/cancer/guide/pdfs/ACT2.pdf
,
Masters: http://science.education.nih.gov/supplements/nih1/cancer/guide/pdfs/ACT2M.PDF
Cancer and the Cell Cycle – 5 short animations http://science.education.nih.gov/supplements/nih1/cancer/activities/activity2_animations.htm
Cell Biology and Cancer http://science.education.nih.gov/supplements/nih1/cancer/default.htm
The Faces of Cancer (case studies) http://science.education.nih.gov/supplements/nih1/cancer/guide/activity1-1.htm
, http://science.education.nih.gov/supplements/nih1/cancer/guide/pdfs/ACT1M.PDF
How Cancer Grows (NOVA) http://www.pbs.org/wgbh/nova/body/how-cancer-grows.html
Protein Synthesis animation http://sciencenetlinks.com/tools/protein-synthesis/
Gene Inheritance Lesson Plan http://www.teachersdomain.org/resource/tdc02.sci.life.repro.lp_inherit/
Inheritance of Genetic Disorders Lesson Plan http://www.teachersdomain.org/resource/tdc02.sci.life.gen.lp_disorder/
Cancer Research News http://www.cancer.gov/newscenter/
Gene Therapy Used to Treat Sickle Cell Disease in Mice http://news.nationalgeographic.com/news/2001/12/1213_TVsickle.html
Personal Pedigree assignment http://www.indiana.edu/~ensiweb/connections/genetics/pedi.student.pdf
Heredity and Traits http://learn.genetics.utah.edu/content/begin/traits/
PBS Race, the Power of an Illusion http://www.pbs.org/race/000_General/000_00-Home.htm
PBS Race, the Power of an Illusion teacher information http://www.pbs.org/race/000_About/002_04-teachers.htm
Ovarian cancer case study and PowerPoint presentation http://sciencecases.lib.buffalo.edu/cs/collection/detail.asp?case_id=481&id=481
Animal and plant cell interactive animations: http://www.cellsalive.com/cells/cell_model.htm
Animal cell mitosis animations: http://www.cellsalive.com/mitosis.htm
, http://www.johnkyrk.com/mitosis.html
, http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter2/animation__mitosis_and_cytokinesis.html
23 and Me videos:
“Genetics 101 Part 1 “What are genes?” (4:26) https://www.23andme.com/gen101/genes/
“Genetics 101 Part 2 “What are SNPs?” (1:53) (SNP Single Nucleotide Polymorphism) https://www.23andme.com/gen101/snps/
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The Cell Cycle and Mitosis, Control of Cell Growth
“Genetics 101 Part 3 “Where do your genes come from?” (4:14) https://www.23andme.com/gen101/origins/
“Genetics 101 Part 4 “What is phenotype?” (2:03) https://www.23andme.com/gen101/phenotype/
“Surprisingly Interconnected” (1:00) https://www.23andme.com/members/gallery/interconnected/
Genome BC
Mutations activity http://www.genomebc.ca/education/teachers/classroom-activities/bees-beetles-dna/
Sickle Cell Anemia case study http://www.genomebc.ca/education/teachers/classroom-activities/case-studiesoverview/sickle-cell-anemia/
Possible NetBook Activities:
Animal and plant cell interactive animations: http://www.cellsalive.com/cells/cell_model.htm
Animal cell mitosis animation: http://www.cellsalive.com/mitosis.htm
Mitosis crossword puzzle: http://www.cellsalive.com/puzzles/mitosis/index.html
Percentage of time cells spend in each phase of the cell cycle (NetBook interactive activity) http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/activity_description.html
Mighty Mutation Maker DNA name alias mutation activity: http://nature.ca/genome/04/0413_e.cfm
Materials Needed:
Cards for Impromptu responses
Pipe cleaners and beads for cell cycle activity
Cancer Truth or Myth surveys
Cancer Truth or Myth case studies for ten student groups
Internet access
Projector
NetBooks
Homework
Complete online Cook E-Question on www.edmodo.com
Complete three worksheets on the cell cycle
Study for quiz on the cell cycle
MONDAY, JANUARY 9
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The Cell Cycle and Mitosis, Control of Cell Growth
Beginning of Class (5 minutes)
Teacher will take attendance
Students will respond to Impromptu: What are the three phases of Interphase and what happens during each one? P. 206
Lesson Activities (45 minutes)
Teacher will review Impromptu, respond to student responses, correct misinformation and provide missing information.
Teacher will show cellular transport, diffusion, cell cycle and mitosis video
Teacher will introduce students to pipe cleaner chromosome cell cycle activity and assign student partners
Students will work in pairs to demonstrate chromosomes at each stage of the cell cycle using pipe cleaners and beads
Teacher will distribute Chapter 8 worksheets
End of Class Activities (5 minutes)
Cellular Transport and the Cell Cycle Chapter 8 assessment worksheet
Teacher will remind students to study for cell cycle quiz on Friday
Teacher will remind students to prepare their biology binders for teacher evaluation next Wednesday, January 18
TUESDAY, JANUARY 10
Beginning of Class (5 minutes)
Teacher will take attendance
Students will demonstrate pipe cleaner chromosomes through the phases of the cell cycle
Lesson Activities (45 minutes)
Teacher will review Impromptu, respond to student responses, correct misinformation and provide missing information
Teacher will present uncontrolled cell growth PowerPoint slides
Students will take notes on uncontrolled cell growth
Teacher will present Cancer and the Cell Cycle animation 1 http://science.education.nih.gov/supplements/nih1/cancer/activities/activity2_animations.htm
Teacher will distribute Chapter 8 worksheets
End of Class Activities (5 minutes)
Cellular Transport and the Cell Cycle Chapter 8 Sections 8.2 and 8.3 worksheet
Teacher will remind students to study for cell cycle quiz on Friday
TE894 – Spring 2012 5/7

The Cell Cycle and Mitosis, Control of Cell Growth
WEDNESDAY, JANUARY 11
Beginning of Class (5 minutes)
Teacher will take attendance
Students will respond to Impromptu: What controls the cell cycle? Page 211
Lesson Activities (45 minutes)
Teacher will review Impromptu, respond to student responses, correct misinformation and provide missing information
Teacher will review concepts that will be included on quiz
Teacher will distribute Cancer Truth or Myth surveys
Teacher will individually complete Cancer Truth or Myth surveys
Teacher will assign student partners
Teacher will distribute Cancer Truth or Myth case studies
Student partners will read and evaluate Reading for Evidence short cancer passages and present to class
Student partners will answer questions from classmates about their cases
Teacher will distribute Chapter 8 worksheets
End of Class Activities (5 minutes)
Cellular Transport and the Cell Cycle Chapter 8 Section 8.2 worksheet
Teacher will remind students that new Cook E-question will be posted on edmodo.com.
Teacher will remind students to study for cell cycle quiz on Friday
Teacher will remind students to prepare their biology binders for teacher evaluation next Wednesday, January 18
THURSDAY, JANUARY 12
Beginning of Class (5 minutes)
Teacher will take attendance
Students will respond to Impromptu: What is uncontrolled cell growth? P. 211-213
Lesson Activities (45 minutes)
Teacher will review Impromptu, respond to student responses, correct misinformation and provide missing information
Student partners will read and evaluate Reading for Evidence short cancer passages and present to class
Student partners will answer questions from classmates about their cases
Teacher will answer student questions about the cell cycle
Students will complete previously-distributed worksheets, study for quiz organize biology notebooks for review next week
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The Cell Cycle and Mitosis, Control of Cell Growth
End of Class Activities (5 minutes)
Teacher will remind students that new Cook E-question has been posted on edmodo.com.
Teacher will remind students to study for cell cycle quiz on Friday
Teacher will remind students to prepare their biology binders for teacher evaluation next Wednesday, January 18
FRIDAY, JANUARY 13
Beginning of Class (5 minutes)
Teacher will take attendance
Students will respond to Impromptu: What results from uncontrolled cell division? P. 211
Lesson Activities (45 minutes)
Teacher will review Impromptu, respond to student responses, correct misinformation and provide missing information
Teacher will distribute quiz on the cell cycle
Students will take quiz on the cell cycle
Students will continue watching “And the Band Played On”
End of Class Activities (5 minutes)
Teacher will remind students that new Cook E-question has been posted on edmodo.com.
Teacher will remind students to prepare their biology binders for teacher evaluation next Wednesday, January 18
WEEK OF JANUARY 16-20
Finish watching “And the Band Played On”
Biology Notebook evaluations
Review for Biology I final exam
WEEK OF JANUARY 23-27
Biology I final exam
Student cancer research and PowerPoint presentation projects
DNA and chromosomal mutations
Introduce meiosis
TE894 – Spring 2012 7/7