The 5th China-Korea Joint Symposium on Chemistry (Nov. 22-23, 2012 Hebei University, China) Symposium Presentations November 22 (Thursday) 8:30~8:40 Opening Ceremony, Prof. Zhengping Li (李正平) Morning session I Chairman: Prof. Min Jae Lee (李民宰) 8:40~9:10 Sunmin Ryu (柳三民) 9:10~9:40 Zhengping Li (李正平) 9:40~10:10 Raman spectroscopy studies of 2-dimensional materials Highly sensitive detection of microRNAs by using nanoparticle probes and the techniques of nucleic acid amplification Taking a Picture Morning session II Chairman: Prof. Gang Ma(马 刚) 10:10~10:40 Min Jae Lee (李民宰) Characterization of the Mammalian N-degrons and Development of Heterovalent Inhibitors of the N-recognin 10:40~11:10 Jung Hoon Lee (李荣勋) Dioxin receptor and hepatic lipid metabolism 11:10~11:430 Cuimiao Zhang (张翠妙) Defect-Related Luminescent Materials: Synthesis, Emission Properties, and Applications Afternoon session I 14:00~14:30 14:30~15:00 Chairman: Prof. Sunmin Ryu Min Hyung Lee (李民亨) Huajie Zhu (朱华杰) 15:00~15:30 Afternoon session II 15:30~16:00 16:00~16:30 16:30~18:30 p-InP Nanopillar Photocathodes for Efficient Solar-Driven Hydrogen Production Recent progresses in configurtion determination in medicinal chemsitry Coffee Break Chairman: Prof. Zhengping Li (李正平) Xiaoliang Li (李晓亮) Jingchong Xiao (肖金冲) Development of fluorescent sensors for metal ions Synthesis, physical properties and application based on oligoacene derivatives Exchange and Interview with Students Curriculum vitae Sunmin Ryu Personal Information Assistant Professor Department of Applied Chemistry Kyung Hee University 1 Seocheon Giheung Yongin, 446-701, Korea Email: sunryu@khu.ac.kr http://sunryu.khu.ac.kr Phone: (82)-31-201-2267 Cell Phone: (82)-10-7268-1080 Fax: (82)-31-202-7337 EDUCATION PhD in Physical Chemistry, Seoul National University, Korea, 2005 (advisor: Seong Keun Kim) MS in Physical Chemistry, Seoul National University, Korea, 2000 (advisor: Seong Keun Kim) BS in Chemistry, Seoul National University, Korea, 1998 PROFESSIONAL EXPERIENCE Faculty, Kyung Hee University, Mar 2009 to present Postdoctoral researcher, Columbia University, Apr 2006 to Feb 2009 (Advisor: Louis E. Brus) Postdoctoral researcher, Korea Research Institute of Standards and Science (KRISS), Mar 2005 to Apr 2006 SELECTED PUBLICATIONS 1. J. E. Lee, G. Ahn, J. Shim, Y. S. Lee, and S. Ryu,* “Optical Separation of Mechanical Strain from Charge Doping in Graphene”, Nature Commun. 3, 1024 (2012); 2. J. Shim, C. H. Lui, T. Y. Ko, Y.-J. Yu, P. Kim, T. F. Heinz, and S. Ryu,* “Water-Gated Charge Doping of Graphene Induced by Mica Substrates”, Nano Lett. 12, 648 (2012) 3. S. Ryu,* J. Maultzsch, M. Y. Han, P. Kim, and L. E. Brus, “Raman Spectroscopy of Lithographically Patterned Graphene Nanoribbons”, ACS Nano, 5, 4123 (2011) 4. S. Ryu, Li Liu, S. Berciaud, Y.-J. Yu, H. Liu, P. Kim, G. W. Flynn, and L. E. Brus, “Atmospheric Oxygen Binding and Hole Doping in Deformed Graphene on a SiO2 Substrate”, Nano Lett. 10, 4944 (2010) 5. C. Lee, H. Yan, L. E. Brus, T. F. Heinz, J. Hone and S. Ryu,* “Anomalous Lattice Vibrations of Single- and Few-Layer MoS2”, ACS Nano, 4, 2695 (2010) 6. H. Liu, S. Ryu, Z. Chen, M. L. Steigerwald, C. Nuckolls, and L. E. Brus, “Photochemical Reactivity of Graphene”, J. Am. Chem. Soc. 131, 17099 (2009) 7. Y.-J. Yu, Y. Zhao, S. Ryu, L. E. Brus, K. S. Kim, and P. Kim, “Tuning the Graphene Work Function by Electric Field Effect”, Nano Lett. 9, 3430 (2009) 8. S. Berciaud, S. Ryu, L. E. Brus, and T. F. Heinz, “Probing the Intrinsic Properties of Exfoliated Graphene: Raman Spectroscopy of Free-Standing Monolayers”, Nano Lett. 9, 346 (2009) 9. S. Ryu, M. Y. Han, J. Maultzsch, M. L. Steigerwald, T. F. Heinz, P. Kim, and L. E. Brus, “Reversible Basal Plane Hydrogenation of Graphene”, Nano Lett. 8, 4597 (2008) 10. L. Liu,† S. Ryu,† M. R. Tomasik, E. Stolyarova, N. J. Jung, M. S. Hybertsen, M. L. Steigerwald, L. E. Brus, and G. W. Flynn, “Graphene Oxidation: Thickness Dependent Etching and Strong Chemical Doping”, Nano Lett., 8, 1965 (2008) (†equal authorship) 11. E. Stolyarova, K. T. Rim, S. Ryu, J. Maultzsch, P. Kim, L. E. Brus, T. F. Heinz, M. S. Hybertsen, and G. W. Flynn, “High-resolution Scanning Tunneling Microscopy Imaging of Mesoscopic Graphene Sheets on an Insulating Surface”, Proc. Natl. Acad. Sci. USA, 104, 9209 (2007) 12. S. Ryu, J. Chang, H. Kwon, and S. K. Kim, “Dynamics of Solvated Electron Transfer in Thin Ice Film Leading to a Large Enhancement in Photodissociation of CFCl3”, J. Am. Chem. Soc., 128, 3500 (2006) MIN JAE LEE WORK: Department of Applied Chemistry College of Applied Sciences Kyung Hee University 446-701 Yong-In, Korea (031) 201 – 377 1 email: mjlee@khu.ac.kr HOME: Apt #105-1102 Youngtong 1 dong Suwon, Korea (010) 3951-6051 FAX : (031) 202 - 7337 PROFESSIONAL EXPERIENCE: 2011 - present Assistant Professor, Department of Applied Chemistry, Kyung Hee University Research Projects: 1. Understanding and characterizing regulatory mechanisms of proteasomeassociated proteins 2. Development of small molecule inhibitors/activators of the regulatory proteins 3. Application of the small molecules in various disease models including cancer, cardiac diseases, and neurodegenerative diseases 2011 Full-time Instructor , Department of Applied Chemistry, Kyung Hee University 2007 – 2011 Postdoctoral Research Fellow, Department of Cell Biology, Harvard Medical School Research Projects: 1. Understanding Usp14 as an endogenous inhibitor of the mammalian proteasome 2. Screening and characterizing small molecule inhibitors of Usp14 3. Applying the inhibitors on degradation of various neurodegenerative diseaserelated proteins Principle Investigator: Daniel Finley, Ph.D. EDUCATION & TRAINING: 2007 Ph.D., Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy Research Projects: 1. Identification and characterization of RGS proteins as first in vivo N-end rule substrates 2. Elucidation of the molecular circuits underlying cardiac phenotypes of ATE1-/- mice 3. Development of in vivo small molecule inhibitors of the N-end rule pathway Dissertation title: Role of the N-end rule pathway in cardiovascular development, signaling and homeostasis (Advisor: Yong Tae Kwon, Ph.D.) 2002 M.S., Chemistry, Seoul National University, Korea Research Projects: 1. Organic syntheses of non-viral gene carriers and their in vitro and in vivo applications 2. Development of a novel ovarian cancer mouse model for quantitative study of gene delivery Thesis title: Intraperitoneal gene delivery mediated by a novel cationic liposome in a peritoneal disseminated ovarian cancer model (Advisor: Jong Sang Park, Ph.D.) 2000 B.S., Chemistry, Seoul National University, Korea PUBLICATION 1. An, J. Y., Kim, E., Zakrzewska, A., Yoo, Y. D., Jang, J. M., Han, D. H., Lee, M. J. , Seo, J. W., Lee, Y. J., Kim, T.-Y., de Rooij, D. G., Kim, B. Y., & Kwon, Y. T. UBR2 of the N-end rule pathway is required for chromosome stability vis histone ubiquitylation in spermatocytes and somatic cells. PLoS One, 7, e37414. doi:10.1371/ journal.pone. 0037414 (2012) 2. Son, J. Y., Jung, I., & Lee, M. J. Local crystallization of non-crystallized PbTiO3 thin film by a heated atomic force microscope tip. J Am Ceram Soc 95, 1511-1513 (2012) 3. Lee, J. H., & Lee, M. J. , Emerging roles of the ubiquitin-proteasome system in the steroid receptor signaling. Arch Pharm Res 35, 397-407 (2012) 4. Lee, S., Saito, K., Lee, H.-R., Lee, M. J. , Shibasaki, Y. Oishi, Y., & Kim., B.-S. Hyperbranched Double Hydrophilic Block Copolymer Micelles of Poly(ethylene oxide) and Polyglycerol for pH-sensitive Drug Delivery. Biomacromol 13, 1190-1196 (2012) 5. Pang, S.-C., Hyun, H., Lee, S., Jang, D., Lee, M. J. ,* Kang, S. H.,* & Ahn, K. H.* Photoswitchable fluorescent diarylethene in a turn-on mode for live cell imaging. Chem Commun 48, 3745-3747 (2012) (*: co-corresponding authors) 6. Lee, J. H., & Lee, M. J. Liposome-mediated cancer gene therapy: clinical trials and their lessons to stem cell therapy. Bull Kor Chem Soc 33, 433-442. (2012) 7. Tian, G., Park, S., Lee, M. J. , Huck, B., McAllister, F., Hill, C. P., Gygi, S. P., & Finley, D. An asymmetric interface between the regulatory particle and core particle of the proteasome. Nat Struct Mol Biol 18, 1259-1267 (2011) 8. Lee, B.-H.*, Lee, M. J. *, Park, S., Chen, P.-C., Gartner, C., Oh, D.-C., Dimova, N., Hanna, J., Gygi, S. P., Wilson, M. W., King, R. W., & Finley, D. Enhancement of proteasome activity by a small-molecule inhibitor of Usp14. Nature 467, 179-184. (2010) (*, equal contribution) 9. Lee, M. J. , Lee, B.-H., Hanna, J., King, R. W., & Finley, D. Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes. Mol Cell Proteomics Epub. doi:10.1074/mcp.R110.003871 (2011) 10.Lee, J. H., Wada, T., Febbraio, M., Matsubara, T., He, J., Lee, M. J. , He, J., Gonzalez, F. J., & Xie, W. A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis. Gastroenterology 139, 653-663. (2010) 11.An, J. Y., Kim, E., Jiang, Y., Zakrzewska, A., Kim, D.E., Lee, M. J. , Mook-Jung, I., Zhang, Y., & Kwon., Y. T. UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination. Proc Natl Acad Sci USA 107, 1912- Junghoon Lee Work: Home: Kyung Hee University 150-1102, 955-1 Department of Applied Chemistry Yongtong-dong, Yongtong-gu Yongin-si, Kyungi-do EDUCATIONS 08/2004-04/2009: Suwon-si, Kyungi-do South Korea 446-701 South Korea 443-740 Phone 82-31-201-2444 Cell 82-10-3955-6051 Fax 82-31-201-2340 email: jhlee7802@gmail.com PhD, Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA Mentor: Wen Xie, MD, PhD Thesis title: The role of the aryl hydrocarbon receptor and the liver X receptor in gene regulation and metabolic homeostasis. 08/2001-06/2003: MS, Biochemistry, Seoul National University, Seoul, Korea. Mentor: Jong-sang Park, PhD. Thesis title: Polyplexes assembled with internally quaternized PAMAM- OH dendrimer and plasmid DNA in gene delivery and their potency. 03/1996-02/2001: BS, Chemistry, Dongguk University, Seoul, Korea. PROFESSIONAL EXPERIENCES 09/2012-present: Lecturer, Kyung Hee University Dept. of Chemical Engineering 01/2012-present: Research Fellow, Kyung Hee University Dept. of Applied Chemistry 03/2012-06/2012: Lecturer, Eulji University Dept. of Environmental Health and Safety 08/2012-12/2011: Lecturer, Kunkuk University Dept. of Bioengineering 04/2009-07/2011: Postdoctoral Fellow, Harvard School of Public Health, Boston, MA PUBLICATIONS J.H. Lee, M.J. Lee, Liposome-mediated cancer gene therapy, B. Kor. Chem. Soc. 2012, 33, 433-442 J.H. Lee, M.J. Lee, Emerging roles of the ubiquitin-proteasome system in the steroid receptor signaling, Arch. Pharm. Res., 2012, 35, 397-409 S. Saini, B. Zhang, Y. Niu, J. Gao, Y. Zhai, J. H. Lee, H. Uppal, H. Tian, M. Tortorici, S. Poloyac, W. Qin, R. Venkataramanan, W. Xie, Activation of LXR increases acetaminophen clearance and prevents its toxicity, Hepatology, 2011, 54, 2208-2217 J. He, J. H. Lee, M. Febbraio, W. Xie, The emerging roles of fatty acid translocase (FAT)/CD36 and the aryl hydrocarbon receptor (AhR) in fatty liver disease. Exp. Biol. Med., 2011, 236, 1116-1121. J. H. Lee, P. Giannikopoulos, S. A. Duncan, J. Wang, Johansen, C. T., Brown, J. D., Plutzky, J., R. A. Hegele, L. H. Glimcher, and A. Lee, The transcription factor cyclic AMP response element-binding protein H regulates triglyceride metabolism. Nat. Med. 2011, 17, 812-815. B. Zhang, Q Cheng, Z Ou, J. H. Lee, M. Xu, U. Kochhar, S. Ren, M Huang, B.R. Pflug, W. Xie,. Pregnane X receptor as a therapeutic target to inhibit androgen activity, Endocrinology, 2010, 151, 5721-5719 J. H. Lee, T. Wada, M. Febbraio, T. Matsubara, M.J. Lee, J. He, F.J. Gonzalez, W. Xie, A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis. Gastroenterology, 2010, 139, 653-663 H. Gong, J. He, J.H. Lee, E. Mallick , X. Gao, S. Li, G.E. Homanics, W. Xie, Activation of the liver X receptor prevents lipopolysaccharide-induced lung injury. J. Biol. Chem. 2009, 284, 30113-30121 J. H. Lee, H. Gong, S. Khadem, Y. Lu, X. Gao, S. Li, J. Zhang, and W. Xie, Androgen deprivation by activating the liver X receptor. Endocrinology, 2008, 149, 3778-3788 H. Gong, M. J. Jarzynka, T. J. Cole, J. H. Lee, T. Wada, B. Zhang, J. Gao, W. Song, D. B. DeFranco, S.Cheng, and W. Xie, Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase. Cancer Research, 2008, 68, 7386-7393 J. H. Lee, J. Zhou and W. Xie, PXR and LXR in hepatic steatosis: A new dog and an old dog with new tricks, Mol. Pharm., 2008, 5, 60-66 (featured as a most-accessed article of the 1st quarter of 2008) Min Hyung Lee Department of Applied Chemistry, Kyung Hee University 1732 Deogyeong-daero, Yongin, Gyeonggi, Korea Tel.: +82-31-201-3881 E-mail: minhlee@khu.ac.kr Employment History Assistant Professor Mar 2012 - present Department of Applied Chemistry, Kyung Hee University, Yongin, South Korea. Post-doctoral Fellow Aug 2011 – Feb 2012 Joint Center for Artificial Photosynthesis (JCAP), Lawrence Berkeley present National Laboratory (LBNL), Berkeley, California, USA Advisor: Dr. Joel Ager Research Theme: Development of High-Efficiency Water Splitting Cells Post-doctoral Scholar July 2010 - Aug 2011 Department of EECS, University of California at Berkeley, Berkeley, CA Advisor: Professor Ali Javey Research Theme: Development of Large-area Nanoscale Electronic and Photovoltaic Devices Education Ph. D., Chemistry June 2010 Department of Chemistry, Northwestern University, Evanston, IL Advisor: Professor Teri W. Odom Thesis Title: Soft Nanolithographic Approaches for Patterning Large-area Plasmonic Structures M.S., Analytical Chemistry Feb 2003 Department of Chemistry, Kwangwoon University, Seoul, Republic of Korea Thesis Advisor: Professor Geun Sig Cha Thesis Title: Development of Calcium Ion Sensor with Reduced Anionic Interference B.S., Chemistry Feb 2001 Department of Chemistry, Kwangwoon University, Seoul, Republic of Korea Advisor: Professor Geun Sig Cha Research Project Post-doctoral Fellow, Joint Center for Artificial Photosynthesis (JCAP), Lawrence Berkeley National Laboratory (LBNL), Berkeley, California, USA 2011-present, Berkeley, CA -efficiency water splitting Post-doctoral Scholar, EECS, University of California at Berkeley 2010-2011, Berkeley, CA -efficiency water splitting -to-roll nano-texturization methods -top sub-50 nm nanopatterning methods for nanoelectronics Graduate Research Assistant, Chemistry, Northwestern University 2004-Present, Evanston, IL Min Hyung Lee – Curriculum Vitae 3 Publications (Paper) 1. M. H. Lee, K. Takei, J. Zhang, R. Kapadia, M. Zheng, Y.-Z. Chen, J. Nah, T. S. Matthews, Y.-L. Chueh, J. W. Ager, A. Javey. "p-InP nanopillar photocathodes for highly efficient, solar-driven hydrogen production," Angew. Chem. Int. Ed., 2012, 51, 10760-10764. Hot Paper 2. J. Nah, H. Fang, C. Wang, K Takei, M. H. Lee, E. Plis, S. Krishna, A. Javey. "III-V Complementary metal-oxide-semiconductor Electronics on Si Substrates," Nano Letters, 2012, 12, 3592-3595. 3. M. H. Lee*, N. Lim*, D. J. Ruebusch*, A. Jamshidi, R. Kapadia, R. Lee, T. J. Seok, K. Takei, K. Y. Cho, Z. Fan, H. Jang, M. Wu, G. Cho, A. Javey, "Roll-to-Roll Anodization and Etching of Aluminum Foils for High-Throughput Surface Nano-Texturing," Nano Letters, 2011, 11, 3425-3430. *Equally contributed 4. X. Zhang, C. L. Pint, C. L., M. H. Lee, B. E. Schubert, A. Jamshidi, K. Takei, H. Ko, A. Gillies, R. Bardhan, J. J. Urban, M. Wu, R. Fearing, A. Javey, "Opticallyand Thermally-Responsive Programmable Materials Based on Carbon Nanotube-Hydrogel Polymer Composites," Nano Letters, 2011, 11, 3239-3244. (Highlighted in Nature, 2011, 475, 426; Highlighted in Nanotechweb.org.) 5. Madsen, M.; Takei, K.; Kapadia, R.; Fang, H.; Ko, H.; Takahashi, T.; Ford, A. C.; Lee, M. H.; Javey, A. "Nanoscale Semiconductor “X” on Substrate “Y” – Processes, Devices and Applications," Advanced Materials, 2011, 23, 3115-3127. 6. Cho, K.; Ruebusch, D. J.; Lee, M. H.; Moon, J. H.; Ford, A. C.; Kapadia, R.; Takei, K.; Ergen, O.; Javey, A. "Molecular Monolayers for Conformal, Nanoscale Doping of InP Nanopillar Photovoltaics," Applied Physics Letters, 2011, 98, 203101. 7. Lee, M. H.; Javey, A. "Power Surfing on Waves," Nature (News & Views), 2011, 472, 304-305. 8. Lee, M. H.; Huntington, M. D.; Zhou, W.; Yang, J. -C.; Odom, T. W. "Programmable Soft Lithography: Solvent-assisted Nanoscale Embossing," Nano Letters, 2011, 11, 311-315 (Cover article). (Highlighted in Chemical & Engeneering News, 2010, 88, 41; Highlighted in Nanowerk.com, Futurity.org, and other sites.) 9. Gao, H.; Hyun, J. K.; Lee, M. H.; Yang, J.-C.; Lauhon, L. J.; Odom, T. W. "Broadband Plasmonic Microlenses Based on Patches of Nanoholes," Nano Letters, 2010, 10, 4111-4116. (Highlighted in Nanotechweb.org) 10. Yang, J. -C.; Gao, H.; Suh, J. Y.; Zhou, W.; Lee, M. H.; Odom, T.W. "Enhanced Optical Transmission Mediated by Localized Plasmons in Anisotropic, 3D Nanohole Arrays." Nano Letters, 2010, 10, 3173-3178. 11. Gao, H.; Yang, J.-C.; Lin, J. Y.; Stuparu, A. D.; Lee, M. H.; Mrksich, M.; Odom, T. W. "Using the Angle-Dependent Resonances of Molded Plasmonic Crystals to Improve the Sensitivities of Biosensors," Nano Letters, 2010, 10, 2549-2554. Xiaoliang Li Name Nationality Tel. Email Address XiaoLiang Li P. R. CHINA 82-10-9619-1980 xiaoliangli@khu.ac.kr 443 room, Department of Applied Chemistry, Global Campus, Kyung Hee University, YongIn, 446-701, South Korea. Professional Experience: 3.2011-present Postdoctor in nanoanalytic lab; Department of Applied Chemistry, Kyung Hee University. Advisor: Prof. SungIk Yang Education 9. 2007~2.2011 Ph.D. candidate in nanoanalytic lab; Department of Applied Chemistry, Kyung Hee University. Advisor: Prof. SungIk Yang 9. 2004~7. 2007 Environment M.Sc. Organic Chemistry, College of Chemistry and Science, Hebei University. Advisor: Prof. JiTai Li 9. 2000~7. 2004 B.S. Chemistry, College of Chemistry and Environment Science, Hebei University Research field Organic synthesis under ultrasound Synthesis of fluorescent sensors for heave metal ions PUBLICATIONS 1. Li, Ji-Tai; Li, Xiao-Liang; Li, Tong-Shuang Synthesis of oximes under ultrasound irradiation, Ultrasonics Sonochemistry, 2006, 13, 200-202. 2. Li, Ji-Tai; Li, Xiao-Liang; Li, Tong-Shuang Synthesis of Benzaldoximes in Aqueous Media under Ultrasound Irradiation, Chin. J. Org. Chem. 2006, 26 (11), 1594-1596. 3. Li, Ji-Tai; Li, Xiao-Liang An efficient and practical synthesis of methylene dioximes by combination of ultrasound and phase transfer catalyst, Ultrasonics Sonochemistry, 2007, 14, 677-679. 4. Li, Xiao-Liang; Li, Ji-Tai Synthesis of ketoximes under ultrasound irradiation, Chemical Journal on Internet, 2006, 8(9), 57. 5. Li, Ji-Tai; Liu, Xian-Feng; Li, Xiao-Liang Synthesis of 2,3-Epoxy-1-phenyl-3-(un)substituted Phenyl-1- propanone in Aqueous Media under Ultrasound Irradiation, Chin. J. Org. Chem. 2007 27 (11), 1428-1431. 6. Li, Ji-Tai; Chen, Yan-Xue; Li, Xiao-Liang; Deng, Hai-Jian. An efficient procedure for synthesis of oximes by grinding, Asian Journal of Chemistry 2007, 19(3), 2236-2240. 7. Li, Ji-Tai; Li, Xiao-Liang; Liu, Xian-Feng; MA, Jie-Jie Synthesis of O-Benzyloximes by Combination of Phase Transfer Catalysis and Ultrasound Irradiation, Chin. J. Org. Chem. 2008, 28 (4), 628~631. 8. Li, Xiao-Liang; He, Yong Wu; Yang, Sung Ik Synthesis and Characterization of a Rapid and Highly Selective Fluorescent Hg2+ Sensor in Aqueous Media, Bull. Korean Chem. Soc. 2011, 32, 338-340.