CURRICULUM VITAE
OF
KEHINDE ONWOCHEI OKONJO
1.
2.
PERSONAL PARTICULARS
1.1
Name, with titles:
Prof. Kehinde Onwochei Okonjo, BSc (Hons.) (Chemistry), PhD (Ibadan)
1.2
Status: Professor of Biophysical Chemistry
1.3
Date and place of birth: 15th July, 1942; Lagos, Nigeria
1.4
Postal address:
1.4.1 Official:
Department of Chemistry, Covenant University, Ota, Ogun State
1.5
Nationality: Nigerian
1.6
State of origin: Delta
1.7
Marital status: Married (five children)
INSTITUTIONS ATTENDED
2.1.1 Government School, Ogwashi-Ukwu
1949-1953
2.1.2
Ibadan Boys’ High School (Primary Section), Ibadan.
1954-1955
2.1.3 Banham Memorial Methodist School, Port Harcourt (Primary) 1956
2.1.4
King’s College, Lagos
1957-1961
2.1.5
King’s College, Lagos
1962-1963
School Prefect
House Captain, Hyde-Johnson’s House
2.1.6 University of Ibadan, Ibadan (Undergraduate Studies)
1964-1967
2.1.7 University of Ibadan, Ibadan (Postgraduate Studies)
1969-1972
2.1.8 Goethe Institut, Göttingen
1973
2.1.9 Max-Planck-Institut für Biophysikalische Chemie,
Göttingen, Germany
1973-1975
2.1.10 Medical College of Georgia, Augusta (USA)
1980-1981
2.1.11
3.
4.
Max-Planck-Institut für Ernährungsphysiologie,
Dortmund, Germany
1989-1991
2.1.12 Institut für Physiologische Chemie, Johannes Gutenberg Universität,
Mainz, Germany, 1991
2.1.13 Institut für Anorganische Chemie, Universität Erlangen-Nürnberg,
Erlangen, Germany
1998
EDUCATIONAL QUALIFICATIONS
3.1.1 West African School Certificate
1961
3.1.2
Cambridge Higher School Certificate
1963
3.1.3 BSc (Hons.) Chemistry (University of Ibadan)
1967
3.1.4 PhD Biophysical Chemistry (University of Ibadan)
1972
SCHOLARSHIPS, FELLOWSHIPS & PRIZES
4.3.1 Federal Government of Nigeria Scholarship, 1964-1967
4.3.2 Studentship of the National Institutes of Health (U.S.A.), 1970 – 1972, from a grant
awarded to my PhD supervisor, Professor John G. Beetlestone.
4.3.3 Fellowship of the Alexander von Humboldt Foundation, Bonn, Germany,
for postdoctoral studies, 1973 – 1975
4.3.4 Fellowship of the Alexander von Humboldt Foundation, Bonn, Germany
1989-1990
4.3.5 Fellowship of the Max Planck Society, Germany, 1990 -1991
4.3.6 Winner of the Royal Society of Chemistry Grant for International Authors
(1998) in recognition of my publications in The Journal of the Chemical
Society (Faraday Transactions), an international journal of physical chemistry
1
based in Cambridge, United Kingdom.
MEMBERSHIP OF LEARNED SOCIETIES
5.
5.1
5.2
5.3
5.4
6.
Member, American Chemical Society
Member, New York Academy of Sciences
Life member, Science Association of Nigeria
Member, Chemical Society of Nigeria
RESEARCH GRANTS AWARDED & ACADEMIC DISTINCTIONS
6.1
6.2
6.3
6.4
6.5
Research Grant from the Alexander von Humboldt Foundation, 1975.
Research Grant from the Alexander von Humboldt Foundation, 1982.
Research Grant from the Alexander von Humboldt Foundation, 1991.
Research Grant from the Third World Academy of Sciences/UNESCO, 1995
First Multidisciplinary Research Grant of the Postgraduate School, University of
Ibadan, for science-based disciplines, 1995. Led the team that won the single grant
awarded.
6.6 Research Grant from the Alexander von Humboldt Foundation, 1998
6.7 Research Grant from the Alexander von Humboldt Foundation, 2006
6.8 Research Grant from the Postgraduate School, University of Ibadan, 2006
6.9 At least two of my published papers were refereed by the Nobel Laureate, Max F.
Perutz (now late) of Cambridge University, UK, prior to their publication in the
international journal Biochimica et Biophysica Acta.
WORK AND OTHER PROFESSIONAL EXPERIENCE
7.
7.1
7.2
WORK EXPERIENCE
7.1.1 Molusi College, Ijebu-Igbo (1963.-1964), Master teaching Chemistry
7.1.2 St. Rose’s College, Ogwashi-Ukwu (July –Aug. 1965)
Master teaching Mathematics
7.1.3 Anglican Grammar School, Ubulu-Ukwu (Aug. 1967 – Dec. 1968)
Master teaching Mathematics and Physics
7.1.4 St. Anthony’s College, Ubulu-Ukwu (1968)
Master teaching Chemistry at the Higher School Certificate (HSC) level
7.1.5 Demonstrator in chemistry, Department of Chemistry, University of Ibadan (Jan. 1969
to Feb. 1972)
7.1.6 Research Fellow (Grade II), Department of Chemistry, University of Ibadan (Mar. 1972
– August 1973)
7.1.7 Postdoctoral Research Fellow, Max Planck Institut für Biophysikalische Chemie,
Göttingen, Germany (Nov. 1973 – April 1975)
7.1.8 Lecturer Grade II, University of Benin (April 1975 – Aug. 1976)
7.1.9 Lecturer Grade I, University of Ibadan (Sept. 1976 – Sept. 1981)
7.1.10 Assistant Research Professor, Medical College of Georgia, Augusta (USA) (1980 –
1981
7.1.11 Senior Lecturer, University of Ibadan (Oct. 1981 – Sept. 1994)
7.1.12 Research Fellow, Max Planck Institut für Ernährungsphysiologie, Dortmund,
Germany (1989 – 1991)
7.1.13 Professor, University of Ibadan (Oct. 1994)
OTHER PROFESSIONAL EXPERIENCE
7.2.1
Departmental Examinations Coordinator, Department of Chemistry, University
of Ibadan (1982-1984).
In this position I was responsible for the preparation of the question papers
required for all undergraduate examinations and for the calculation of results. I
was also responsible for liaising with External Examiners.
2
7.2.2
7.2.3
Member, University of Ibadan Senate (1984 to 2007)
Departmental Stores Officer, Department of Chemistry, University of Ibadan,
(1985-1987).
In this position I was responsible for the tracking, ordering and disbursement of
chemicals, instruments and apparatus in the departmental store.
7.2.4 PhD External Examiner, Obafemi Awolowo University, Ife (1987)
7.2.5 Member, Faculty of Science Finance Committee, University of Ibadan (2001-2003).
7.2.6 Chairman, Departmental Welfare Committee, Department of Chemistry,
University of Ibadan, 2000-2006
7.2.7 Chairman, Coffee Room Committee, Department of Chemistry, University of
Ibadan (2000-2006)
7.2.8 External Examiner (undergraduate), University of Lagos (2001-2006)
7.2.9 Member, University of Ibadan Central Appointments & Promotions Committee
(2002/2003 and 2004-2006).
7.2.10 Chairman (2004/2005) of the Committee that investigated allegations of
malpractice in the Dept. of Mathematics, University of Ibadan.
7.2.11 Member of the Planning Committee for the establishment of a Central
Multidisciplinary Research Laboratory, University of Ibadan (2005)
7.2.12 Member and Secretary, Planning and Implementation Committee,
Anioma University of Science and Technology, 2004-2006
7.2.13 Dean, College of Natural and Applied Sciences, Bells University of Technology,
Ota, Ogun State (2006)
7.2.14 Member, Strategic Planning Committee, Bells University of Technology, Ota,
Ogun State.
7.2.15 Chairman, Programme Focus Sub-Committee, Bells University of Technology,
Ota, Ogun State
8.
DETAILS OF TEACHING EXPERIENCE
8.1
TEACHING OF RECEIVED KNOWLEDGE AT SECONDARY SCHOOL
LEVEL
8.1.1 Master teaching Chemistry at Molusi College, Ijebu-Igbo, 1963-1964
8.1.2 Master teaching mathematics, St. Roses College, Ogwashi-Ukwu, July-Aug. 1965
8.1.3 Master teaching mathematics and physics, Anglican Grammar School, Ubulu-Ukwu, 1967-1968
8.1.4 Master i/c chemistry at the Higher School Certificate level, St. Anthony’s College, Ubulu-Ukwu,
1968
8.2 TEACHING OF RECEIVED KNOWLEDGE AT UNIVERSITY LEVEL (BSc AND MSc)
8.2.1 Thermodynamics and kinetics, University of Benin, 1975-1976
8.2.2 Thermodynamics and kinetics, University of Ibadan, 1976 to 2006
8.2.3 Thermodynamics, kinetics, statistical mechanics, University of Ibadan, 1981 to 2006
8.2.4 Structures and Functions of Biological Macromolecules (MSc), University of Ibadan
8.2.5 Chemical Relaxation Kinetics (MSc), University of Ibadan, 1981 to 2006
8.2.6 Physical and Inorganic Chemistry (100-200 levels), Bells University of Tech., Ota.
9.
TEACHING OF KNOWLEDGE CREATION (RESEARCH) AT
POSTGRADUATE LEVEL
9.1 I have supervised 8 PhD and 27 MSc theses in the following areas:
9.1.1 Thermodynamics of ligand binding to aquomethemoglobins.
9.1.2 Temperature jump kinetic studies and mechanism of ligand binding to
aquomethemoglobins.
9.1.3 pH dependence of ligand binding to aquomethemoglobins.
9.1.4 Temperature jump studies of conformational changes in hemoglobins.
9.1.5 Studies on abnormal hemoglobins and hemoglobinopathies.
3
9.1.6 Reactivities of the sulphydryl groups of hemoglobins with one reactive sulphydryl group as a
function of pH.
9.1.7 Reactivities of the sulphydryl groups of hemoglobins with multiple reactive sulphydryl groups
as a function of pH.
9.1.8 Equilibrium studies of the reactions of hemoglobins with Ellman’s reagent,
5,5'-dithiobis(2-nitrobenzoate)
9.1.9 Kinetic studies of the reactions of hemoglobins with Ellman’s reagent,
5,5'-dithiobis(2-nitrobenzoate)
9.2 SUPERVISION OF KNOWLEDGE CREATION (RESEARCH) -COMPLETED MSc THESES
9.2.1 Godwin Onuoha (MSc, University of Ibadan, 1982), Professor, Federal University of
Technology, Owerri.
Thesis: Thermodynamics of inositol hexakisphosphate binding to carbonmonoxyhemoglobin
9.2.2 C.O. Ubochi (MSc, University of Ibadan, 1982), Senior Lecturer, Imo State University, Uturu
Thesis: Relaxation studies of isomerization in carbonmonoxyhemoglobin
9.2.3 E.I. Iwuoha (MSc, University of Ibadan, 1983), Professor, University of Western Cape, Cape
Town, South Africa
Thesis: Relaxation amplitude analysis of thiocyanate binding to human methemoglobin A
9.2.4 O.J. Odeyemi (MSc, University of Ibadan, 1983), Lecturer at a college of education (address
unknown)
Thesis: Kinetics of cyanide binding to the methaemoglobin of pigeon.
9.2.5 C.O. Aboluwoye (MSc, University of Ibadan, 1986), Professor of Chemistry, Ondo State
University, Akumgba
Thesis: Kinetic analysis of cyanide binding to methemoglobins A and S
9.2.6 T.O. Okia (MSc, University of Ibadan, 1988), Ugandan national (address and current position
unknown)
Thesis: The pH dependence of the reactivities of the sulphydryl groups of pigeon hemoglobin
9.2.7 I.A. Adejoro (MSc, University of Ibadan, 1988), Lecturer, University of Ibadan
Thesis: The pH dependence of the kinetics of the reaction of 5,5'-dithiobis(2-nitrobenzoic
acid) with the sulphydryl groups of dog hemoglobin
9.2.8 Florence A. Oloo (MSc, University of Ibadan, 1992) Kenyan national and Lecturer, Jomo
Kenyatta University, Nairobi
Thesis: Kinetic studies of the reaction of 5,5'-dithiobis(2-nitrobenzoic acid with guinea pig
Haemoglobin
9.2.9 J.O. Babalola (MSc, University of Ibadan, 1993) Senior Lecturer, University of Ibadan
Thesis: Kinetics of cyanide binding to chicken hemoglobin
9.2.10 N.A.A Babarinde (MSc, University of Ibadan, 1993) Senior Lecturer, Olabisi Onabanjo
University, Ago Iwoye
Thesis: The pH dependence of the reactivities of the sulphydryl groups of chicken
hemoglobin
9.2.11 F. U. Akhigbe (MSc, University of Ibadan, 1994) Lecturer, University of Ibadan
Thesis: Effect of ionic strength on the pH dependence profile of the reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with human hemoglobins
9.2.12 Ita A. Usanga (MSc, University of Ibadan, 1994) Whereabouts unknown.
Thesis: The effect of the dimer-tetramer equilibrium on the sulphydryl reactivity of
haemoglobin
9.2.13 Oladele Oyelakin (MSc, University of Ibadan, 1997) Lecturer, University of Gambia, Banjul
Determination of the tetramer-dimer equilibrium constant of rabbit hemoglobin
9.2.14 Adedayo A. Fodeke (MSc → PhD conversion examination, University of Ibadan, 2001)
Lecturer, Obafemi Awolowo University, Ile-Ife
Thesis: Effects of pH, ionic strength and inositol hexakisphosphate on the reactivity of the
sulphydryl groups of rabbit hemoglobin
9.2.15 Abimbola M. Babafunso (MSc, University of Ibadan, 2002) Assistant Lecturer, University
of Ibadan
4
Thesis: Kinetics of the reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with guinea fowl
carbonmomoxyhemoglobin
9.2.16 E.O. Fehintola (MSc, University of Ibadan, 2002) Lecturer, Adeyemi College of Education,
Ondo
Thesis: Kinetics of the reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with guinea fowl
methemoglobin
9.2.17 Olugbenga S. Bello (MSc, University of Ibadan, 2002) Lecturer, Ladoke Akintola
University of Technology, Ogbomoso
Thesis: Kinetics of the reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with guinea fowl
oxyhemoglobin
9.2.18 T.A. Adesipo (MSc, University of Ibadan, 2002) PhD student, University of Ibadan
Thesis: Reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with human hemoglobin A treated
with carboxypeptidase A
9.2.19 Faith Momoh (MSc, University of Ibadan, 2003) Assistant Lecturer, University of
Agriculture, Makurdi
Thesis: Reversible reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with human hemoglobin A
9.2.20 E.F. Olasehinde (MSc, University of Ibadan, 2003) Assistant Lecturer & postgraduate
student, Federal University of Technology, Akure
Thesis: Kinetics of the reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with rabbit
oxyhemoglobin
9.2.21 Matthew A. Adebayo (MSc, University of Ibadan, 2004) PhD student, University of
Ibadan
Thesis: Kinetics of the reaction of 2,2′-dithiobispyridine with guinea pig
carbonmonoxyhemoglobin
9.2.22 A.M. Akinlade (MSc, University of Ibadan, 2004) Lecturer, College of Education, Ilesa
Thesis: Determination of reactive sulphydryl groups in guinea pig oxyhemoglobin and
kinetics of reaction of 2,2′-dithiobispyridine with guinea pig oxyhemoglobin
9.2.23 Vincent O. Akpoveta (MSc, University of Ibadan, 2005) Lecturer, College of Education,
Agbor, Delta State.
Thesis: Equilibrium studies of the reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with
pigeon hemoglobin
9.2.24 Kamil O. Yusuff (MSc, University of Ibadan, 2005) PhD student, University of Ibadan.
Thesis: Equilibrium studies of the reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with
guinea pig hemoglobin
9.2.25 Omolara Adeboye (MSc, University of Ibadan, 2006) Lecturer, College of Education, Oyo
The pH dependence of the equilibrium constant for the reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with cow hemoglobin
9.2.26 Musbaudeen Abdulhameed (MSc, University of Ibadan, 2006)
Kinetics of the reversible reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with rabbit
carbonmonoxyhemoglobin
9.2.27 Oluwatoyin Ajelabi (MSc, University of Ibadan, 2006) PhD student, University of Ibadan.
Kinetics of the reversible reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with rabbit
oxyhemoglobin
9.3
SUPERVISION OF KNOWLEDGE CREATION (RESEARCH) – MSc
THESES IN PROGRESS
--
9.4
SUPERVISION OF KNOWLEDGE CREATION (RESEARCH) -COMPLETED PhD THESES
9.4.1
E.I. Iwuoha (PhD, University of Ibadan, 1986). Professor, University of Western
Cape, Cape Town, South Africa
5
Thesis: The role of the transition between iron spin states in the reaction of
methemoglobin with ligands
9.4.2 C.O. Aboluwoye (PhD, University of Ibadan, 1990). Professor, Adekunle Ajasin
University, Akungba, Ondo State.
Thesis: Effect of electrostatically linked ionizable groups on the sulphydryl reactivities of
hemoglobins
9.4.3 J.O. Babalola (PhD, University of Ibadan, 1999). Senior Lecturer, University of Ibadan,
Ibadan
Thesis: Effects of neighbouring groups and aggregation state on the reactivities of
hemoglobin sulphydryl groups
9.4.4 Sarah O. Nwozo (PhD, University of Ibadan, 1999). Lecturer Grade I, University of
Ibadan.
Thesis: Influence of allosteric effectors on the reactivities of the F9[93]β and B5[23]β
sulphydryl groups of chicken and pigeon hemoglobins
9.4.5 N.A.A. Babarinde (PhD, University of Ibadan, 2003). Senior Lecturer, Olabisi Onabanjo
University, Ago-Iwoye, Ogun State.
Thesis: Reactivities of the sulphydryl groups of duck hemoglobins
9.4.6 A.A. Fodeke (PhD, University of Ibadan, 2005). Lecturer Grade I, Obafemi Awolowo
University, Ile-Ife.
Thesis: Equilibrium and kinetic studies of the reactivities of the sulphydryl groups of the
major and minor haemoglobins of the domestic cat (felis catus)
9.4.7. O.S. Bello (PhD, University of Ibadan, 2008). Lecturer Grade I, Ladoke Akintola
University of Technology, Ogbomosho.
Thesis: Equilibrium and kinetic parameters of the reaction of 5,5′-dithiobis(2
nitrobenzoate) with the sulphydryl groups of the haemoglobins of the quail (Cortunix
cortunix japonica).
9.4.8 I.A. Adeogun (PhD, University of Ibadan, 2009), Lecturer Grade II, University of
Agriculture, Abeokuta.
Thesis: Equilibrium and kinetic parameters of the reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with the haemoglobins of the sheep
9.4.9 Matthew Adebayo (PhD, University of Ibadan, 2009), Lecturer Grade II, Ajayi Crowther
University, Oyo.
Thesis: Equilibrium and kinetic parameters of the reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with the hemoglobins of the guinea fowl
9.5
SUPERVISION OF KNOWLEDGE CREATION (RESEARCH) – PhD
THESES IN PROGRESS
After my retirement on Sept. 30, 2007, the University of Ibadan requested me to continue
supervising my PhD students who were yet to complete their doctoral work. The remaining seven (7)
students and their PhD projects are:
9.5.1 John Ajaelu, Equilibrium and kinetic studies of the reaction of Ellman’s reagent
with the hemoglobins of the goat
9.5.2 Temilade A. Adediji, Equilibrium and kinetic studies of the reaction of Ellman’s
6
reagent with the hemoglobins of turkey
9.5.3 Fred Akhigbe, Equilibrium and kinetic parameters of the reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with the hemoglobins of the goose
9.5.4 Orighomisan B. Atolaye, Equilibrium and kinetic parameters of the reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with donkey hemoglobin
9.5.5 Oluwatoyin Ajelabi
Equilibrium and kinetic parameters of the reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with chicken hemoglobins
9.5.6 Abimbola Olatunde
Equilibrium and kinetic parameters of the reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with horse hemoglobins
10.
PUBLICATIONS
10.1
BOOKS AND MONOGRAPHS
10.1.1
Huisman, T.H.J., Webber, B., Okonjo, K.O., Reese, A.L. & Wilson, J.B. (1981)
The separation of human hemoglobin chains by high pressure liquid
chromatography in Advances in Hemoglobin Analysis (Alan R. Liss Inc., New
York) pp. 23-38
10.1.2
Atoms, Molecules and Intermolecular Forces in Fundamental Physical
Chemistry (K.O. Okonjo, ed.) Ibadan University Press (2005) pp. 1-35
10.1.3 History of Science in Science, Industry and Mankind (K.O. Okonjo & A.T.
Bolarinwa, eds.) (2006).
10.2
ARTICLES IN NIGERIAN JOURNALS
10.2.1 Okonjo, K.O. & Vega-Catalan, F.J. (1986)
Temperature-jump studies on hemoglobin: Derivation of a relaxation time
expression for an isomerization involving dimers and tetramers
Nigerian Journal of Applied Science 3, 63-79
10.2.2 Okonjo, K.O. (1987)
Theoretical aspects of the effect of heme-linked ionisable groups on the kinetics
of ligand binding to ferric hemeproteins
Nigerian Journal of Applied Science 5, 9-15
10.2.3 Fodeke, A.A., Aboluwoye, C.O. & Okonjo, K.O. (2005)
The effect of thiol-linked ionisable groups on the kinetics of reaction of
haemoglobin with 5,5'-dithiobis(2-nitrobenzoate)
Ife Journal of Science 7, 229-236
10.3
ARTICLES IN INTERNATIONAL JOURNALS
10.3.1 Beetlestone, J.G. & Okonjo, K.O. (1976)
The variation with ionic strength of the formation constant for the azide complex
of methaemoglobins of guinea pig and pigeon
Journal of the Chemical Society (Dalton Transactions) pp. 1257-1259
10.3.2 Beetlestone, J.G., Goddard, J.E. & Okonjo, K.O. (1976)
The reactions of azide, formate and fluoride ions with chemically modified
7
methemoglobins
Journal of the Chemical Society (Dalton Transactions) pp. 1271-1275
10.3.3 Beetlestone, J.G., Adeosun, O.S., Goddard, J.E., Ogunlesi, M.M. & Okonjo,
K.O. (1976)
The acid Bohr effect
Journal of the Chemical Society (Dalton Transactions) pp. 1275-1278
10.3.4 Okonjo, K.O. & Ilgenfritz, G. (1978)
Temperature-jump studies on formate binding to methemoglobin and
metmyoglobin
Archives of Biochemistry and Biophysics 189, 499-507
10.3.5 Okonjo, K.O., Taiwo, A., Balogun, M. & Ekisola, O.B. (1979)
Reactivities of the sulphydryl groups of dog hemoglobin
Biochimica et Biophysica Acta 576, 30-38
10.3.6 Okonjo, K.O. (1980)
Kinetic and thermodynamic parameters of the iron spin state transition in human
aquomethemoglobin
European Journal of Biochemistry 105, 329-334
10.3.7 Okonjo, K.O. (1980)
The effect of organic phosphates on the sulphydryl reactivities of
oxyhemoglobins A and S
Journal of Biological Chemistry 255, 3274-3277
10.3.8 Huisman, T.H.J., Gravely, M.E., Webber, B., Okonjo, K.O., Henson, J. &
Reese, A.L. (1981)
The gamma chain heterogeneity of fetal hemoglobin in black thalassemia and
HPFH heterozygotes
Blood 58, 62-70
10.3.9 Huisman, T.H.J., Altay, C., Webber, B., Reese, A.L., Gravely, M.E., Okonjo, K.O. &
Wilson, J.B. (1981)
Quantitation of three types of gamma chain of hemoglobin by HPLC
Blood 87, 75-82
10.3.10 Huisman, T.H.J., Reese, A.L., Webber, B., Okonjo, K.O., Altay, C. & Felice, A.E.
(1981)
In vitro synthesis of hemoglobin and hemoglobin chains
American Journal of Hematology 10, 227-237
10.3.11 Iwuoha, E.I. & Okonjo, K.O. (1985)
Relaxation amplitude analysis of thiocyanate and formate binding to human
aquomethemoglobin
Biochimica et Biophysica Acta 829, 327-334
10.3.12 Vega-Catalan, F.J., Odeyemi, O.J. & Okonjo, K.O. (1986)
The effect of heme-linked ionisable groups on cyanide binding to methemoglobin
Journal of Biological Chemistry 261, 10576-10581
10.3.13 Okonjo, K.O. & Iwuoha, E.I. (1986)
Subunit iron spin heterogeneity in human aquomethemoglobin
Biochimica et Biophysica Acta 873, 304-307
8
10.3.14 Okonjo, K.O. & Vega-Catalan, F.J. (1987)
The uptake of protons by heme-linked ionisable groups on azide binding to
methemoglobin
European Journal of Biochemistry 169, 413-416
10.3.15 Okonjo, K.O. & Iwuoha, E.I. (1989)
Kinetic and amplitude analyses of thiocyanate binding to chemically modified
human aquomethemoglobins A
African Journal of Science & Technology, Series B, 3, 24-32
10.3.16 Okonjo, K.O., Vega-Catalan, F.J. & Ubochi, C.O. (1989)
Temperature-jump studies on hemoglobin: Kinetic evidence for a non-quaternary
isomerization process in deoxy- and carbonmonoxyhemoglobin
Journal of Molecular Biology 208, 347-354
10.3.17 Okonjo, K.O., Kuhlmann, J. & Maelicke, A. (1991)
A second pathway of activation of the torpedo acetylcholine receptor channel
European Journal of Biochemistry 200, 371-377
10.3.18 Kuhlmann, J., Okonjo, K.O. & Maelicke, A. (1991)
Desensitization is a property of the cholinergic binding region of the nicotinic
acetylcholine receptor-integral ion channel
Federation of European Biochemical Societies Letters 279, 216-218
10.3.19 Okonjo, K.O. & Aboluwoye, C.O. (1992)
Ionizable groups linked to the reaction of hemoglobin with 2,2'-dithiobispyridine
Biochimica et Biophysica Acta 1159, 303-310
10.3.20 Iwuoha, E.I. & Okonjo, K.O. (1993)
Temperature-jump method for determining the equilibrium constant of the iron
spin states in human haemoglobin A
Journal of the Chemical Society (Faraday Transactions) 89, 1361-1364
10.3.21 Iwuoha, E.I. & Okonjo, K.O. (1993)
Role of the relaxation of the iron (III) ion spin states equilibrium in the kinetics
of ligand binding to methaemoglobin
Journal of the Chemical Society (Faraday Transactions) 89, 3921-3924
10.3.22 Okonjo, K.O. & Okia, T.O. (1993)
Hemoglobins with multiple reactive sulphydryl groups: The reaction of pigeon
hemoglobin with 5,5'-dithiobis(2-nitrobenzoic acid)
Journal of Protein Chemistry 12, 639-646
10.3.23 Okonjo, K.O. & Adejoro, I.A. (1993)
Hemoglobins with multiple reactive sulphydryl groups: The reaction of dog
hemoglobin with 5,5'-dithiobis(2-nitrobenzoic acid)
Journal of Protein Chemistry 12, 33-37
10.3.24 Schrattenholz, A, Coban, T., Schroeder, B., Okonjo, K.O., Kuhlmann, J.,
Pereira, E.F., Albuqueque, E.X. & Maelicke, A. (1993)
Biochemical characterization of a novel channel-activating site on nicotinic
acetylcholine receptors
Journal of Receptor Research 13 (1-4) 393-412
10.3.25 Okonjo, K.O., Aboluwoye, C.O., Babalola, J.O. & Usanga, I.A. (1995)
Organic phosphate binding groups electrostatically linked to the reactivity of the
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CysF9[93]β sulphydryl group of human haemoglobin A
Journal of the Chemical Society (Faraday Transactions) 91, 2095-2100
10.3.26 Okonjo, K.O., Aken’ova, Y., Aboluwoye, C.O., Nwozo, S., Akhigbe, F.U.,
Babalola, J.O. & Babarinde, N.A.A. (1996)
Effect of the A3[6] βGlu→Val mutation on the reactivity of the CysF9[93]β
sulphydryl group of human haemoglobin S
Journal of the Chemical Society (Faraday Transactions) 92, 1739-1746
10.3.27 Aboluwoye, C.O., Okonjo, K.O., Moosavi-Movahedi, A.A. & Bordbar, A.K.
(1996)
Effect of anionic surfactants on the reaction of 2,2'-dithiobispyridine with bovine
oxyhemoglobin as a function of temperature
Italian Journal of Biochemistry 45, 357-362
10.3.28 Okonjo, K.O. & Nwozo, S. (1997)
Ligand-dependent reactivity of the CysB5[23]β sulphydryl group of the major
haemoglobin of chicken.
Journal of the Chemical Society (Faraday Transactions) 93, 1361-1366
10.3.29 Babalola, J.O., Uko, L.U., Okonjo, K.O. & van Eldik, R. (2002)
Hemoglobins with multiple reactive sulphydryl groups: Reaction of
5,5'-dithiobis(2-nitrobenzoic acid) with guinea pig hemoglobin
Bulletin of the Chemical Society of Ethiopia 16, 175-186
10.3.30 Okonjo, K.O. & Fodeke, A. (2006)
Reversible reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with the hemoglobins
of the domestic cat: Acetylation of NH3+ terminal group of the β
chain transforms the complex pH dependence of the forward apparent second
order rate constant to a simple form.
Biophysical Chemistry 119 (2), 196-204
10.3.31 Okonjo, K.O., Fodeke, A. & Kehinde, T.A. (2006)
Reversible reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with the hemoglobins
of the domestic cat (felis catus): Variation of the equilibrium and reverse rate
constants with pH.
Biophysical Chemistry 121 (1) 65-73
10.3.32 Okonjo, K.O., Adediji, T.A., Fodeke, A.A., Adeboye, O. & Ezeh, C.V. (2007)
Transition of hemoglobin between two tertiary conformations: Determination of
equilibrium and thermodynamic parameters from the reaction of 5,5'-dithiobis(2nitrobenzoate) with the CysF9[93]β sulfhydryl group
Biophysical Chemistry 128, 56-62
10.3.33 Okonjo, K.O., Bello, O.S., Babalola, J.O. (2008)
Transition of hemoglobin between two tertiary conformations: The transition constant
differs significantly for the major and minor hemoglobins of the Japanese quail
(Cortunix cortunix japonica)
Biochimica et Biophysica Acta 1784, 464-471.
10.3.34 Okonjo, K.O., Adeogun, I., Babalola, J.O. (2009)
Transition of hemoglobin between two tertiary conformations: Inositol
hexakisphosphate increases the transition constant and the affinity of sheep
haemoglobins for 5,5'-dithiobis(2-nitrobenzoate)
Biochimica et Biophysica Acta 1794, 398-409.
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10.3.35 Okonjo, K.O., Adeogun, I., Babalola, J.O. (2010)
Tertiary conformational transition in sheep haemoglobins induced by reaction with
5,5´-dithiobis(2-nitrobenzoate) and by binding of inositol hexakisphosphate
Biophysical Chemistry 146, 65-75.
11. Conference Paper
11.1 Okonjo, K.O., Kuhlmann, J. & Maelicke, A. (1990)
A new pathway of activation of the nicotinic acetylcholine receptor?
88. Konferenz der Gesellschaft für Biologische Chemie (Biochemie des
Nervensystems) (Proceedings of the Autumn meeting of the Neurochemistry Study
Group held 18-19 October 1990 in Mainz, Germany) pp. 1037-1038
12. Hobbies:
Reading; walking
11