Manipulative Physiol Ther. 1999 Jun;22(5):348-9. Comparative efficacy of conservative medical and chiropractic treatments for carpal tunnel syndrome: a randomized clinical trail. Davis PT, Hulbert JR, Kassak KM, Meyer JJ. Northwestern College of Chiropractic, Bloomington, MN 55431, USA. OBJECTIVE: To compare the efficacy of conservative medical care with chiropractic care in the treatment of carpal tunnel syndrome. DESIGN: Two-group, randomized, single-blind trial with 9 wk of treatment and a 1-month follow-up interview. SETTING: Wolfe-Harris Center for Clinical Studies at Northwestern College of Chiropractic in Bloomington, Minnesota. PATIENTS: Ninety-one of 96 eligible subjects who reported symptoms that were confirmed by clinical exam and nerve conduction studies. INTERVENTIONS: Interventions included ibuprofen (800 mg 3 times a day for 1 wk, 800 mg twice a day for 1 wk and 800 mg as needed to a maximum daily dose of 2400 mg for 7 wk) and nocturnal wrist supports for medical treatment. Chiropractic treatment included manipulation of the soft tissues and bony joints of the upper extremities and spine (three treatments/week for 2 wk, two treatments/week for 3 wk and one treatment/week for 4 wk), ultrasound over the carpal tunnel and nocturnal wrist supports. MAIN OUTCOME MEASURES: Outcome measures were pre- and postassessments of self-reported physical and mental distress, nerve conduction studies and vibrometry. RESULTS: There was significant improvement in perceived comfort and function, nerve conduction and finger sensation overall, but no significant differences between groups in the efficacy of either treatment. CONCLUSIONS: Carpal tunnel syndrome associated with median nerve demyelination but not axonal degeneration may be treated with commonly used components of conservative medical or chiropractic care. : J Manipulative Physiol Ther. 1994 May;17(4):246-9. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt=pub med_pubmed&from_uid=8046280>Related Articles, Links Chiropractic manipulation in carpal tunnel syndrome. Valente R, Gibson H. Department of Chiropractic Principles and Practice, Cleveland Chiropractic College and Clinic, Kansas City, MO. OBJECTIVE: To determine if chiropractic manipulation could relieve carpal tunnel syndrome (CTS). CLINICAL FEATURES: A 42-yr-old female suffered from pain, tingling and numbness in the right wrist. Paresthesia along the C6 dermatome, a positive Phalen's test and Tinel's sign was present. EMG testing confirmed the clinical diagnosis of CTS. INTERVENTION AND OUTCOME: Chiropractic manipulations were rendered 3 times per week for 4 wk, to the subject's cervical spine, right elbow and wrist using a low amplitude, short lever, low force, high velocity thrust. Significant increase in grip strength and normalization of motor and sensory latencies were noted. Orthopedic tests were negative. Symptoms dissipated. CONCLUSION: In this case study, chiropractic made a demonstrable difference through objective and subjective outcomes. Further investigations using double-blind, cross-over designs with larger samples are warranted. J Okla State Med Assoc. 2002 Jan;95(1):7-14. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt=pub med_pubmed&from_uid=11799804>Related Articles, Links Conservative treatment of carpal tunnel syndrome: an outcome study of adjunct exercises. Seradge H, Parker W, Baer C, Mayfield K, Schall L. Orthopaedic & Reconstructive Center, 1044 SW 44th Street, 6th Floor, Oklahoma City, OK 73109, USA. We conducted a prospective study to evaluate the effect of a new non-surgical protocol for treating carpal tunnel syndrome (CTS). It incorporates the Carpal Tunnel Decompression Exercise Program (Exercise Program) into conventional non-surgical treatment. Twenty-eight patients (33 hands) met the inclusion criteria and were followed for 18 months. The outcome measurement tools used were the Symptom Severity Scale (SSS) and the Functional Status Scale (FSS). The outcome tools were administered at admission and repeated at 1, 2, and 18 months after admission to the treatment program. Using the adjunct treatment, 80% of the hands in the mild category and 71% in the moderate category were successfully treated without surgery. All patients in the severe category required surgery. The average success rate of our adjunct non-surgical treatment protocol was 67%, a substantial improvement over the 18% to 34% success rate reported nationally for conventional treatment methods. Furthermore, improvement in the outcome of carpal tunnel syndrome by the adjunct non-surgical treatment can result in significant savings in human suffering, medical cost, lost work time, and socioeconomic distress. PMID: 11799804 [PubMed - indexed for MEDLINE] J Am Osteopath Assoc. 1998 Dec;98(12):679-86. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt=pub med_pubmed&from_uid=9885488>Related Articles, Links Comment in: * <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abst ract&list_uids=9885484>J Am Osteopath Assoc. 1998 Dec;98(12):662. Manipulative treatment of carpal tunnel syndrome: biomechanical and osteopathic intervention to increase the length of the transverse carpal ligament. Sucher BM, Hinrichs RN. Center For Carpal Tunnel Studies, Paradise Valley, AZ 85253, USA. SucherCTS@msn.com To quantify the amount of transverse carpal ligament (TCL) elongation in response to osteopathic manipulation or sustained load bearing (or both), a study involving seven cadaver limbs was conducted. Distances from the trapezium to the hamate (distance A) and from the scaphoid to the pisiform (distance B) were measured in five mounted cadaver limbs during and after the limbs bore the weight (2 newtons [N] to 4 N) for 2 several-hour periods. A several-hour period occurred between the weight bearing to assess recoil. Distances A and B were measured before and after the limbs were manipulated, according to previously described techniques, as well as with a new maneuver, termed the "guywire" technique. Two dissected limbs also were subjected to further weight bearing, this time increased to 8 N. Greater weight loads produced greater lengthening of the TCL, and recoil after removal of weight loads was slower than recoil after manipulation. Manipulation was more effective than weight loading for increasing distance A (distal canal), but weight loading generally was more effective than manipulation for increasing distance B (proximal canal). The guywire manipulation combined with direct transverse extension appeared to have the greatest impact on lengthening the TCL distally. These results show promise for the effective use of manipulation and load bearing for TCL elongation and nonsurgical relief of pressure on the median nerve in patients with carpal tunnel syndrome. PMID: 9885488 [PubMed - indexed for MEDLINE] References 1. Tetro AM, Evanoff BA, Hollstein SB, Gelberman RH. A new provocative test for carpal tunnel syndrome. Assessment of wrist flexion and nerve compression. J Bone Joint Surg Br. 1998:80(3):493-8. 2. Davis PT, Hulbert JR, Kassak KM, Meyer JJ. 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Oakland, CA: New Harbinger Publications, 2001. 3. Prudden B. Pain Erasure. New York: M. Evans & Co., 1980.