Educational Fact Sheet: Medical Marijuana 8/23/10 Disclaimer: The W-ONE Legislative Committee, as an educational service to its membership, develops fact sheets to provide information on previous or potential legislative issues. A W-ONE approved “Educational Fact Sheet” does not present a position for or against the issue. Introduction: Cannabis preparations have been used as a remedy for thousands of years. The use of this plant in traditional medicine has been documented in a range of countries, extending from China to the rest of the world. It is used for the treatment of strained muscles, convulsions, asthma, depression, pain, nausea and vomiting or as an appetite stimulant. At this time the possible medical applications of the plant or its natural or synthetic pharmacologically active agents are tightly restricted both for ethical and legal reasons. Research: There have been many studies done on the use of medical marijuana and results differ from study to study which unfortunately does not help either side in this debate. The American Academy of Pain Medicine in 2009 printed a study done by researchers from Spain and Japan on the use of marijuana for medical purposes. They found evidence of efficacy in the use of marijuana for patients with chronic pain, and also found it helpful in the treatment of nausea and vomiting in patients undergoing chemotherapy. Yet they also found a high number of serious adverse events in the short term, principally associated with the central nervous system, including: effects on cognitive function, motor function and alterations in perceptions. Their conclusion was that use of marijuana for pain control would entail more risk than benefit. In another study done by a group from the Department of Anesthesiology from the University of San Diego, they wanted to study the effect of smoked marijuana on pain. What they found was that in low doses the marijuana had no effect on pain, with medium doses it significantly reduced pain and in high doses it actually increased the pain. They felt that they cannot advocate a place for using the drug in the treatment of pain due to more information needed about abuse potential, tolerance, efficacy in neuropathic pain, and safety issues of inhaled marijuana. Concern over the clinical use of inhaled marijuana are health related issues that result from the delivery method; long term use has been shown to be associated with increased respiratory symptoms suggestive of chronic lung disease and also digestive cancers. They too found concerns with some side effects as they relate to psychotropic effects, such as depressed mood. The UCLA School of Medicine conducted a study in 1997 on 243 marijuana smokers over an 8 year period. They reported the following: Findings from the long term study of heavy, habitual marijuana smokers demonstrated that neither the continuing or intermittent smokers exhibited any significantly different rates of decline in lung function as compared to those individuals who never smoked marijuana. In an article from the Canadian Medical Association Journal, they referenced a research study that was done by the Australian National Health and Medical Research Council. What this council found in their study was that the short term use of marijuana for medical purposes had an acceptable safety profile. They found that most of the adverse events were not serious; dizziness was the most common of these. Thus, they felt that short term use for symptom relief of nausea and vomiting in cancer treatment and for the relief of acute pain would be acceptable. Since their trials were of short duration (8-12 months) they felt they could not comment of use of marijuana for long term use such as in chronic disorders like MS. Summary of Pros and Cons Pros Marijuana is effective at relieving nausea and vomiting; especially cased by chemotherapy used to treat cancer Marijuana can relieve spasticity of the muscles that is sometimes associated with MS and paralysis Marijuana can help treat appetite loss associated with HIV-AIDS and certain types of cancers Marijuana can relieve certain types of pain Marijuana is safe, safer in fact than many other prescribed medications to treat the same symptoms Studies do show that smoking marijuana alone (without the concurrent use of tobacco) does not increase the risk of lung disease Marijuana has been used for centuries as a medicinal agent with good effect Cons Frequent marijuana use can seriously affect your short-term memory Frequent use can impair your cognitive ability Smoking anything can seriously damage your lung tissue, however, marijuana smoke contains 50-70% more carcinogenic ingredients than cigarette smoke Not enough evidence supports marijuana as a n effective pain relieving agent Marijuana carries a risk of abuse and addiction Smoked marijuana contains cancer-causing compounds Smoked marijuana has been implicated in a high percentage of automobile accidents and workplace accidents Other States Response: 14 states and Washington D.C. have now adopted medical marijuana laws since 1996, those states are: Alaska California Colorado Hawaii Maine Michigan Montana New Jersey New Mexico Nevada Oregon Rhode Island Vermont Washington Washington D.C. These states have laws which allow patients to use and possess small quantities of marijuana for medical purposes without being subject to state criminal penalties. They also allow a patient’s caregiver, which is an adult who agrees to assist with a patient’s medical use of marijuana to possess but not use marijuana. Most state laws protect “qualifying patients” who have received a diagnosis of a debilitating medical condition and have written documentation from their physician indicating that they might or would benefit from the medical use of marijuana or that the benefits outweigh the risks involved. Definitions of debilitating conditions vary by state, but typically include: HIV-AIDS, cachexia, cancer, glaucoma, epilepsy and other seizure disorders, severe nausea, severe and chronic pain, muscle spasms from MS or Crohn’s disease and some other conditions also. State laws do not regulate quality or potency and most don’t address how to obtain the drug. Most all states allow patients to cultivate the drug, but do limit the amount they can cultivate. Missing from many state laws is a requirement that physicians recommending use of marijuana to adult patients provide the rudimentary disclosure of risks and benefits necessary for informed consent. This disclosure is required for minors. Wisconsin’s Legislative Response: Jackie Rickert, a state activist and a long-time Mondovi patient has been leading the cause to get legislation introduced regarding use of marijuana in the state of Wisconsin. This past legislative year 2009-2010, Assembly Bill 554 and Senate Bill 368 were introduced into Wisconsin legislature under the support of Representative Mark Pocan (D- Madison) and Senator Jon Erpenbach (D- Waunakee). The legislation was very similar to what the other states have in place. However, the session ended prior to these bills getting passed. Governor Doyle supported this legislation. In December of 2009 there was a public hearing on this bill and there was a combination of 104 patients and physicians testifying or registering their support of this legislation and only 6 against it. This legislation will now have to be re-introduced and depending on how elections go in the fall, it is uncertain what kind of support this legislation will get. In the meantime, this activist group is working within counties to place local advisory referendums in support of this legislation on their November ballots, Dane County voted in July to do this in November. Organizations in Support: - Wisconsin Nurses Association (Oct. 1999) - American Nurses Association (March 2004) - American Civil Liberties Union(2005) - Wisconsin Public Health Association (1999) - American Bar Association(1998) - American Public Health Association (Jan. ,1995) - American Academy of HIV Medicine (2003) - American Academy of Family Physicians( 2001) - Lymphoma Foundation of America (Jan. 1997) - Institute of Medicine (1999) Organizations in Opposition: American Medical Association (No. 2008) - The Wisconsin Medical Society does not feel that marijuana is any more helpful than other current drugs on the market for pain control (2009) The U.S. Drug Enforcement Administration is not in favor of legalizing the use of marijuana - Crohn’s and Colitis Foundation of America (Oct. 2009) - National Eye Institute (May 2009) - National Multiple Sclerosis Society (Mar. 2009) - US Food and Drug Administration (Sept. 2009) Organizations neither in support or opposition: The American Medical Association has recently called for changing the status of marijuana from a Schedule 1 to a Schedule II drug in order to enable more research on medical marijuana No information was able to be found on this topic from the American Organization of Nurse Executives Conclusion: Obviously, there are opposing views on this subject matter. One question is who should be deciding what is best for patients; individuals and their physicians or federal bureaucrats? Supporters of medical marijuana want to protect medical privacy and the physician/patient relationship. Opponents are looking to put some control by government on these decisions. Although some states have enacted laws, we need to remember that Federal law still treats the use of marijuana as a criminal offense even if the use is for medical reasons. The DEA has actually increased enforcement efforts against Americans who use or grow marijuana for medicinal use, even in states where such use is legal under state law. Thus, the battle continues and it does not seem that the fight will be over soon. Prepared by: Joyce Schaefer, Adm. Pt. Care Services Amery Regional Medical Center and Legislative Committee of the W-ONE Bibliography Articles: 1. Degenhardt, Louisa and Wayne D. Hall. “The adverse effects of cannabinoids: implications for use of medical marijuana.” Canadian Medical Association Journal, 17 June 2008: 1685-1686. 2. Hoffmann, Diane E. and Ellen Weber. “Medical Marijuana and the Law.” The New England Journal of Medicine Vol. 362; 16, 22 April 2010: 1453-1457. 3. Sanchez, Eva Martin, Toshiaki A. Furukawa, Julian Taylor and Jose Luis R. Martin. “Systematic Review and Meta-analysis of Cannabis Treatment for Chronic Pain.” American Academy of Pain Medicine Vol. 10, Number 8, 2009: 1353-1368. 4. Seamon, Matthew J., Jennifer A. Fass, Maria Maniscalco-Feichti, and Nada A. AbuShraie. “Medical marijuana and the developing role of the pharmacist.” American Journal Health System Pharmacists Vol.64, 15 May 2007: 1037-1044. 5. Wallace, Mark, et al. “Dose dependent Effects of Smoked Cannabis on CapsaicinInduced Pain and Hyperalgesia in Healthy Volunteers.” Anesthesiology Vol. 107, No. 5, November 2007: 785-795. Websites: 1. “Medical Marijuana.” ProCon.org. 8 May 2008. 23 August 2010. http://www.medicalmarijuana.procon.org/view.source.php?sourceID=001402 2. “Medical Marijuana Fact Sheet.” DrugPolicy.org. 9 June 2004. 21 August 2010. http://www.drugpolicy.org/library/factsheets/06_09_04mmjfactsheet.cfm 3. “Speaking out against Drug Legalization.” U.S. Drug Enforcement Administration. May 2003. 25 August 2010. http://www.justice.gov/dea/demand/speakout/index.html 4. “What are the Pros and Cons of Medical Marijuana?” About.com. 26 April 2009. 5 August 2010. http://dying.about.com/od/symptommanagement/f/med_mj_procon.htm