Building the Backbone
In the nucleus you have nucleotide triphosphates dTTP, dATP, dGTP and
dCTP
If you break off 2 phosphates get a huge amount
of Energy released (just like when the cell uses
ATP in other reactions)
To build the backbone DNA Polymerase takes a nucleotide triphosphate minus
2 of the phosphates and uses the energy to build the phosphodiester bond
between the OH on the 3’ carbon of the nucleotide above to the P on the 5’
carbon from the new nucleotide (the one that has lost the 2 phosphates).
Telomers
Telomers - http://faculty.plattsburgh.edu/donald.slish/Telomerase.html