俞松良，国立阳明大学微生物及免疫学研究所博士，台湾大学博士后。自 2002
年起，先后在国立台湾大学杨泮池的生物晶片实验室、国立台湾大学医研部任教
职。现任国立台湾大学医学院医事检验暨生物技术学系副教授、国立台湾大学附
设医院检验医学部兼任医检师。致力于基因体学、肿瘤医学及微生物学研究.由
基因层次（DNA、RNA、核糖核酸和表观基因体）探讨癌生成与转移的机制、
发展癌症标记及预测肺癌病人的复发与存活率，最终找出癌症标记，并针对个别
病人的状况进行个人化医疗评估。现任国立台湾大学医学检验暨生物技术学系副
教授和国立台湾大学附设医院检验医学部兼任医检师
教育经历
1986 年-1990 年，国立台湾大学医学院医事技术学系 学士
1990 年-1992 年，国立台湾大学医事技术学研究院 硕士
1992 年-1999 年，国立阳明大学微生物及免疫学研究所 博士
工作经历
1999 年-2003 年． 国立台大医院 外科部 博士后研究
2003 年-2006 年，台湾大学医学院基因体医学研究中心 博士后研究
2005 年-2007 年，台湾大学附设医院医学研究部 助理研究员
2007 年-2010 年，台湾大学医学检验暨生物技术学系 助理教授
2010 年- 至今，
国立台湾大学医学检验暨生物技术学系 副教授
国立台湾大学附设医院检验医学部 兼任医检师
荣誉：
2009 年 经济部生物科技研发成果创意应用竞赛银牌奖
2009 年 经济部生物科技研发成果创意应用竞赛佳作奖。
2009 年 国科会「科学 50」研究团队。
2007 年 国科会杰出技术移转贡献奖。
2007 年 国立台湾大学医学院新聘专任教师教学研究额外加给。
Selected articles
1. Kang-Yi Su; Hsuan-Yu Chen; Ker-Chau Li; Min-Liang Kuo; James Chih-Hsin
Yang; Wing-Kai Chan; Bing-Ching Ho; Gee-Chen Chang; Jin-Yuan Shih;
Sung-Liang Yu; et al.Pretreatment Epidermal Growth Factor Receptor (EGFR)
T790M Mutation Predicts Shorter EGFR Tyrosine Kinase Inhibitor Response
Duration in Patients With Non-Small-Cell Lung Cancer.Journal of clinical
oncology : official journal of the American Society of Clinical Oncology 2012;
30(4):433-40.
2. Wan-Yu Hsieh; Cheng-Chung Chou; Chao-Chi Ho; Sung-Liang Yu; Hsuan-Yu
Chen; Han-Yi E Chou; Jeremy J W Chen; Huei-Wen Chen; Pan-Chyr Yang.
Single-walled carbon nanotubes induce airway hyperreactivity and parenchymal
injury in mice.American journal of respiratory cell and molecular biology 2012;
46(2):257-67.
3. Shinsheng Yuan; Sung-Liang Yu; Hsuan-Yu Chen; Yi-Chiung Hsu; Kang-Yi Su;
Huei-Wen Chen; Chih-Yi Chen; Chong-Jen Yu; Jin-Yuan Shih; Yih-Leong Chang;
et al.Clustered genomic alterations in chromosome 7p dictate outcomes and
targeted treatment responses of lung adenocarcinoma with EGFR-activating
mutations.Journal of clinical oncology : official journal of the American Society of
Clinical Oncology 2011;29(25):3435-42.
4.Xiaoming Yang; Qian Shi; Shuenn-Chen Yang; Chi-Yuan Chen; Sung-Liang Yu;
Kenneth F Bastow; Susan L Morris-Natschke; Pei-Chi Wu; Chin-Yu Lai;
Tian-Shung Wu; et al.Antitumor agents 288: design, synthesis, SAR, and biological
studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as
potent and selective antitumor agents.Journal of medicinal chemistry 2011;54(14):
5097-107.
5.Tzu-Hua Chang; Meng-Feng Tsai; Kang-Yi Su; Shang-Gin Wu; Cheng-Po Huang;
Sung-Liang Yu; Yung-Luen Yu; Chou-Chin Lan; Chih-Hsin Yang; Shwu-Bin Lin;
et al.Slug confers resistance to the epidermal growth factor receptor tyrosine kinase
inhibitor.American journal of respiratory and critical care medicine 2011;183(8):
1071-9.
6.Kyoko Nakagawa-Goto; Pei-Chi Wu; Kenneth F Bastow; Shuenn-Chen Yang;
Sung-Liang Yu; Hsuan-Yu Chen; Jau-Chen Lin; Masuo Goto; Susan L
Morris-Natschke; Pan-Chyr Yang; et al.
Antitumor agents 283. Further elaboration of desmosdumotin C analogs as potent
antitumor agents: activation of spindle assembly checkpoint as possible mode of
action.
Bioorganic & medicinal chemistry 2011;19(5):1816-22.
7. Bing-Ching Ho; Sung-Liang Yu; Jeremy J W Chen; Sui-Yuan Chang; Bo-Shiun
Yan; Qi-Sheng Hong; Sher Singh; Chuan-Liang Kao; Hsuan-Yu Chen; Kang-Yi Su;
et al.Enterovirus-induced miR-141 contributes to shutoff of host protein translation
by targeting the translation initiation factor eIF4E.Cell host &
microbe 2011;9(1):58-69.
8.Jen-Yi Lee; Yee-Ming Lee; Gee-Chen Chang; Sung-Liang Yu; Wan-Yu Hsieh;
Jeremy J W Chen; Huei-Wen Chen; Pan-Chyr Yang.Curcumin induces EGFR
degradation in lung adenocarcinoma and modulates p38 activation in intestine: the
versatile adjuvant for gefitinib therapy.PloS one 2011;6(8):e23756.
9.Chi-Yu Lai; Sung-Liang Yu; Ming H Hsieh; Chun-Houh Chen; Hsuan-Yu Chen;
Chun-Chiang Wen; Yung-Hsiang Huang; Po-Chang Hsiao; Chuhsing Kate Hsiao;
Chih-Min Liu; et al. MicroRNA expression aberration as potential peripheral blood
biomarkers for schizophrenia.PloS one 2011;6(6):e21635.
10.T-C Lin; H-A Hou; W-C Chou; D-L Ou; S-L Yu; H-F Tien; L-I Lin.CEBPA
methylation as a prognostic biomarker in patients with de novo acute myeloid
leukemia.Leukemia : official journal of the Leukemia Society of America,
Leukemia Research Fund, U.K 2011;25(1):32-40.
11. Bo-Zhi Chen; Sung-Liang Yu; Sher Singh; Li-Pin Kao; Zong-Yun Tsai;
Pan-Chyr Yang; Bai-Hsiun Chen; Steven Shoei-Lung Li.Identification of
microRNAs expressed highly in pancreatic islet-like cell clusters differentiated
from human embryonic stem cells.Cell biology international 2011;35(1):29-37.
12.Sung-Liang YU; Shih-bin LIN; Yung-luen YU; Min-hui CHIEN; Kuo-jung SU;
Ching-Ju LIN; Tzong-der WAY; Giou-Teng YIANG; Chai-Ching LIN; De-Chuan
CHAN; et al. Isochaihulactone protects PC12 cell against H(2)O(2) induced
oxidative stress and exerts the potent anti-aging effects in D-galactose aging
mouse model.Acta pharmacologica Sinica 2010;31(12):1532-40.
13. Da-Liang Ou; Ying-Chun Shen; Sung-Liang Yu; Kuen-Feng Chen; Pei-Yen Yeh;
Hsiang-Hsuan Fan; Wen-Chi Feng; Ching-Tzu Wang; Liang-In Lin; Chiun Hsu;
et al.Induction of DNA damage-inducible gene GADD45beta contributes to
sorafenib -induced apoptosis in hepatocellular carcinoma cells.Cancer
research 2010;70(22): 9309-18.
14. Yung-Li Yang; Shu-Rung Lin; Jiann-Shiuh Chen; Chih-Cheng Hsiao; Kai-Hsin
Lin; Jiunn-Ming Sheen; Chao-Neng Cheng; Kang-Hsi Wu; Shu-Wha Lin;
Sung-Liang Yu; et al.Multiplex reverse transcription-polymerase chain reaction
as diagnostic molecular screening of 4 common fusion chimeric genes in
Taiwanese children with acute lymphoblastic leukemia.Journal of pediatric
hematology/ oncology 2010;32(8):e323-30.
15.Sheng-Yi Lin; Chi-Mei Hsueh; Sung-Liang Yu; Chih-Chung Su; Weng-Yoon
Shum; Kuan-Chuan Yeh; Gee-Chen Chang; Jeremy J W Chen.HLJ1 is a novel
caspase-3 substrate and its expression enhances UV-induced apoptosis in nonsmall cell lung carcinoma.Nucleic acids research 2010;38(18):6148-58.
16.Steven Shoei-Lung Li; Sung-Liang Yu; Sher Singh.Epigenetic states and
expression of imprinted genes in human embryonic stem cells.World journal of
stem cells 2010;2(4):97-102.
17.Shih-Ting Cha; Pai-Sheng Chen; Gunnar Johansson; Chia-Yu Chu; Ming-Yang
Wang; Yung-Ming Jeng; Sung-Liang Yu; Jin-Shing Chen; King-Jen Chang;
Shiou-Hwa Jee; et al.MicroRNA-519c suppresses hypoxia-inducible factor-1alpha
expression and tumor angiogenesis.Cancer research 2010;70(7):2675-85.
18.Pei-Min Chen; Yi-Ywan M Chen; Sung-Liang Yu; Singh Sher; Chern-Hsiung Lai;
Jean-San Chia.Role of GlnR in acid-mediated repression of genes encoding
proteins involved in glutamine and glutamate metabolism in Streptococcus
mutans.Applied and environmental microbiology 2010;76(8):2478-86.
19.Kai-Hung Wang; An-Pei Kao; Sher Singh; Sung-Liang Yu; Li-Pin Kao; Zong
Yun Tsai; Sin-Daw Lin; Steven Shoei-Lung Li.Comparative expression profiles of
mRNAs and microRNAs among human mesenchymal stem cells derived from
breast, face, and abdominal adipose tissues.The Kaohsiung journal of medical
sciences 2010;26(3):113-22.
20.Tzu-Pei Chang; Sung-Liang Yu; Sheng-Yi Lin; Yi-Jing Hsiao; Gee-Chen Chang;
Pan-Chyr Yang; Jeremy J W Chen.Tumor suppressor HLJ1 binds and functionally
alters nucleophosmin via activating enhancer binding protein 2alpha complex
formation.
Cancer research 2010;70(4):1656-67.
21.Yung-Luen Yu; Sung-Liang Yu; Kuo-Jung Su; Chyou-Wei Wei; Min-Hui Jian;
Po-Cheng Lin; I-Hsuan Tseng; Chai-Ching Lin; Chin-Cheng Su; De-Chuan Chan;
et al.Extended O6-methylguanine methyltransferase promoter hypermethylation
following n-butylidenephthalide combined with 1,3-bis(2-chloroethyl)-1
-nitrosourea (BCNU) on inhibition of human hepatocellular carcinoma cell
growth.Journal of agricultural and food chemistry 2010;58(3):1630-8.
22.Zong-Yun Tsai; Sher Singh; Sung-Liang Yu; Chi-Hsien Chou; Steven
Shoei-Lung Li.A feeder-free culture using autogeneic conditioned medium for
undifferentiated growth of human embryonic stem cells: comparative expression
profiles of mRNAs, microRNAs and proteins among different feeders and
conditioned media.BMC cell biology 2010;11():76.
23.Yung-Li Yang; Shu-Rung Lin; Jiann-Shiuh Chen; Shu-Wha Lin; Sung-Liang Yu;
Hsuan-Yu Chen; Ching-Tzu Yen; Chien-Yu Lin; Jing-Fang Lin; Kai-Hsin Lin; et
al.Expression and prognostic significance of the apoptotic genes BCL2L13, Livin,
and CASP8AP2 in childhood acute lymphoblastic leukemia.Leukemia
research 2010;34(1):18-23.
24.Zong-Yun Tsai; Sher Singh; Sung-Liang Yu; Li-Pin Kao; Bo-Zhi Chen; BingChing Ho; Pan-Chyr Yang; Steven Shoei-Lung Li.Identification of microRNAs
regulated by activin A in human embryonic stem cells..Journal of cellular
biochemistry 2010;109(1):93-102.