CURRICULUM VITAE
Name: Pauline Mary Rudd PhD, MA (Oxon), B.Sc., L.R.I.C. Date of Birth: 17.09.42
Address: 29, Sadlers Court,
Abingdon, Oxon, OX14 2PA
Marah’s, Knockaphrumpa, Roundwood, Moneystown, Co Wicklow, Ireland
HIGHER EDUCATION
1961-1964 B.Sc. Special Chemistry Westfield College, University of London
1967 L.R.I.C. (Licentiate of the Royal Institute of Chemistry)
1995 Ph.D. The Open University, Milton Keynes
1998 MA Oxon
EXPERIENCE
1964-1969: Wessex Biochemicals/Sigma London: Founding Scientist, Senior Chemist
responsible for Research, Development and Production of sugars and sugar phosphates.
Restart of Career after bringing up 4 children:
1983-present Department of Biochemistry, University of Oxford
1983-1984: Research Technician, Glycobiology Institute
1984-1996: Post Graduate Research Assistant
1996- 2000 Senior Research Fellow
1996-present Head of GlycoImmunology group
1998-2000 University Research lecturer
2000-2006 University Reader in Glycobiology
Current position: NIBRT Professor of Glycoproteomics and Glycobiology at University College, Dublin
Other positions held concurrently:
1991-1993 Glycoconjugate Journal: Assistant to Advisory Editor
1991-present University Liason Officer for Technology Transfer to Oxford GlycoSciences
1993-2002 Consultant to Oxford GlycoSciences Ltd.
1996-1999 Biochemistry Departmental committee
1996-present: Senior Departmental Teaching Associate (Dept. of Biochemistry)
Co-Chair: Committee for organising Rodney Porter Annual Memorial Lecture
1996-2000 Chair: D.Phil. induction course and transferable skills courses
1998- present Scientific Advisory Board for Jenner bi-annual conferences
1998-1999 Visiting Research Associate, The Scripps Research Institute, La Jolla, CA
1999-2001 Visiting Professor of Biochemistry, Shanghai Medical University, PRC
2001 Visiting scientist Ben Gurion University of the Negev, Israel
2002 Elected Founder member: International Society for Science and Religion
2000- Committee member, Wellcome graduate student scheme
2002- 2005 Royal Society Committee for Grants for Eastern Europe
2003 Examiner Part 2, Biochemistry Department, Oxford University
2003-4 Scientific Advisory Board for FEBS course in Croatia (2004)
2000-3 Scientific Advisory Board for Immunology Programme, FIU,Miami
2004 Erskine Visiting Fellow, Canterbury University, Christchurch, New Zealand
Annual entry in Who’s Who in the World 1997-present
PUBLICATIONS
1. Wittwer, A.J., et al., Effects of N-glycosylation on in vitro activity of Bowes melanoma and
2. human colon fibroblast derived tissue plasminogen activator.
Biochemistry, 1989. 28 (19): p.
7662-9.
Parekh, R.B., et al., N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell
3. line.
Biochemistry, 1989. 28 (19): p. 7670-9.
Rudd, P.M., et al., Diversification of the IgG molecule by oligosaccharides.
Mol Immunol,
1991. 28 (12): p. 1369-78.
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Rudd, P.M., et al., Separation and analysis of the glycoform populations of ribonuclease B using capillary electrophoresis.
Glycoconj J, 1992. 9 (2): p. 86-91.
Opdenakker, G., et al., Concepts and principles of glycobiology.
Faseb J, 1993. 7 (14): p.
1330-7.
Field, M.C., et al., Structural analysis of the N-glycans from human immunoglobulin A1: comparison of normal human serum immunoglobulin A1 with that isolated from patients with rheumatoid arthritis.
Biochem J, 1994. 299 ( Pt 1) : p. 261-75.
Rudd, P.M., et al., Glycoforms modify the dynamic stability and functional activity of an enzyme.
Biochemistry, 1994. 33 (1): p. 17-22.
Rudd, P.M., et al., A human T-cell receptor recognizes 'O'-linked sugars from the hinge region of human IgA1 and IgD.
Immunology, 1994. 83 (1): p. 99-106.
Rudd, P.M., et al., The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator.
Biochim Biophys Acta, 1995.
1248 (1): p. 1-10.
Mori, K., et al., The activation of type 1 and type 2 plasminogen by type I and type II tissue plasminogen activator.
J Biol Chem, 1995. 270 (7): p. 3261-7.
Opdenakker, G., et al., Cells regulate the activities of cytokines by glycosylation.
Faseb J,
1995. 9 (5): p. 453-7.
Malhotra, R., et al., Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein.
Nat Med, 1995. 1 (3): p. 237-43.
Rudd, P., et al., Lectin-carbohydrate interactions in disease. T-cell recognition of IgA and
IgD; mannose binding protein recognition of IgG0.
Adv Exp Med Biol, 1995. 376 : p. 147-52.
Iourin, O., et al., The identification of abnormal glycoforms of serum transferrin in carbohydrate deficient glycoprotein syndrome type I by capillary zone electrophoresis.
Glycoconj J, 1996. 13 (6): p. 1031-42.
Guile, G.R., et al., A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles.
Anal Biochem, 1996.
240 (2): p. 210-26.
Zapun, A., et al., Conformation-independent binding of monoglucosylated ribonuclease B to calnexin.
Cell, 1997. 88 (1): p. 29-38.
Rudd, P.M., et al., The glycosylation of the complement regulatory protein, human erythrocyte CD59.
J Biol Chem, 1997. 272 (11): p. 7229-44.
Wormald, M.R., et al., Variations in oligosaccharide-protein interactions in immunoglobulin
G determine the site-specific glycosylation profiles and modulate the dynamic motion of the
Fc oligosaccharides.
Biochemistry, 1997. 36 (6): p. 1370-80.
Rudd, P.M. and R.A. Dwek, Glycosylation: heterogeneity and the 3D structure of proteins.
Crit Rev Biochem Mol Biol, 1997. 32 (1): p. 1-100.
Rudd, P.M. and R.A. Dwek, Rapid, sensitive sequencing of oligosaccharides from glycoproteins.
Curr Opin Biotechnol, 1997. 8 (4): p. 488-97.
Rudd, P.M., et al., Oligosaccharide sequencing technology.
Nature, 1997. 388 (6638): p.
205-7.
Mehta, A., et al., A strategy for anti-viral intervention: the use of alpha-glucosidase inhibitors to prevent chaperone-mediated folding of viral envelope glycoproteins.
Biochem Soc Trans,
1997. 25 (4): p. 1188-93.
Rudd, P.M., et al., Roles for glycosylation in the anti-inflammatory molecule CD59.
Biochem
Soc Trans, 1997. 25 (4): p. 1177-84.
Mattu, T.S., et al., The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fc alpha receptor interactions.
J Biol Chem,
1998. 273 (4): p. 2260-72.
Rudd, P.M., et al., The glycosylation of the complement regulatory protein, human erythrocyte CD59.
Adv Exp Med Biol, 1998. 435 : p. 153-62.
Hennet, T., et al., Genomic cloning and expression of three murine UDP-galactose: beta-Nacetylglucosamine beta1,3-galactosyltransferase genes.
J Biol Chem, 1998. 273 (1): p. 58-
65.
Roberts, D.B., et al., Mutant analysis reveals an alternative pathway for N-linked glycosylation in Drosophila melanogaster.
Eur J Biochem, 1998. 253 (2): p. 494-8.
Routier, F.H., et al., Quantitation of the oligosaccharides of human serum IgG from patients with rheumatoid arthritis: a critical evaluation of different methods.
J Immunol Methods,
1998. 213 (2): p. 113-30.
Van den Steen, P., et al., Concepts and principles of O-linked glycosylation.
Crit Rev
Biochem Mol Biol, 1998. 33 (3): p. 151-208.
Mehta, A., et al., Alpha-glucosidase inhibitors as potential broad based anti-viral agents.
FEBS Lett, 1998. 430 (1-2): p. 17-22.
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McAlister, M.S., et al., Structural analysis of the CD5 antigen--expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1.
Eur J Biochem, 1998. 257 (1): p. 131-41.
Van den Steen, P., et al., Oligosaccharides of recombinant mouse gelatinase B variants.
Biochim Biophys Acta, 1998. 1425 (3): p. 587-98.
Rudd, P.M., M.R. Wormald, and R.A. Dwek, Glycosylation and the immune system.
J
Protein Chem, 1998. 17 (6): p. 519.
Rudd, P.M., et al., Glycoproteins: rapid sequencing technology for N-linked and GPI anchor glycans.
Biotechnol Genet Eng Rev, 1999. 16 : p. 1-21.
Rudd, P.M., et al., Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells.
Glycobiology, 1999. 9 (5): p. 443-58.
Watson, M., et al., Sugar printing rheumatic diseases: a potential method for disease differentiation using immunoglobulin G oligosaccharides.
Arthritis Rheum, 1999. 42 (8): p.
1682-90.
Rudd, P.M., et al., Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.
Biochemistry, 1999. 38 (42): p. 13937-50.
Rudd, P.M., et al., Roles for glycosylation of cell surface receptors involved in cellular immune recognition.
J Mol Biol, 1999. 293 (2): p. 351-66.
Rudd, P.M., et al., Glycosylation differences between the normal and pathogenic prion protein isoforms.
Proc Natl Acad Sci U S A, 1999. 96 (23): p. 13044-9.
Martinez-Pomares, L., et al., Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor.
J Biol Chem, 1999.
274 (49): p. 35211-8.
Devasahayam, M., et al., The glycan processing and site occupancy of recombinant Thy-1 is markedly affected by the presence of a glycosylphosphatidylinositol anchor.
Glycobiology, 1999. 9 (12): p. 1381-7.
Rudd, P.M., et al., Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.
Biochemistry, 2000. 39 (7): p. 1596-603.
Garred, P., et al., Two edged role of mannose binding lectin in rheumatoid arthritis: a cross sectional study.
J Rheumatol, 2000. 27 (1): p. 26-34.
Zitzmann, N., et al., Protein structure controls the processing of the N-linked oligosaccharides and glycosylphosphatidylinositol glycans of variant surface glycoproteins expressed in bloodstream form Trypanosoma brucei.
Glycobiology, 2000. 10 (3): p. 243-9.
Joshi, L., et al., Influence of baculovirus-host cell interactions on complex N-linked glycosylation of a recombinant human protein.
Biotechnol Prog, 2000. 16 (4): p. 650-6.
Mattu, T.S., et al., O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme.
Biochemistry, 2000. 39 (51): p. 15695-704.
Rudd, P.M., et al., A high-performance liquid chromatography based strategy for rapid, sensitive sequencing of N-linked oligosaccharide modifications to proteins in sodium dodecyl sulphate polyacrylamide electrophoresis gel bands.
Proteomics, 2001. 1 (2): p. 285-
94.
Rudd, P.M., et al., Prion glycoprotein: structure, dynamics, and roles for the sugars.
Biochemistry, 2001. 40 (13): p. 3759-66.
Rudd, P.M., et al., Glycosylation and the immune system.
Science, 2001. 291 (5512): p.
2370-6.
Garner, B., et al., Structural elucidation of the N- and O-glycans of human apolipoprotein(a): role of o-glycans in conferring protease resistance.
J Biol Chem, 2001. 276 (25): p. 22200-8.
Rudd, P.M., G. Opdenakker, and R.A. Dwek, Holistic approaches to glycobiology.
Nat
Biotechnol, 2001. 19 (6): p. 531-2.
Garner, B., et al., Characterization of human apolipoprotein B100 oligosaccharides in LDL subfractions derived from normal and hyperlipidemic plasma: deficiency of alpha-Nacetylneuraminyllactosyl-ceramide in light and small dense LDL particles.
Glycobiology,
2001. 11 (10): p. 791-802.
Saphire, E.O., et al., Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.
Science, 2001. 293 (5532): p. 1155-9.
Peretz, D., et al., Antibodies inhibit prion propagation and clear cell cultures of prion infectivity.
Nature, 2001. 412 (6848): p. 739-43.
Van den Steen, P.E., et al., Matrix remodelling enzymes, the protease cascade and glycosylation.
Biochim Biophys Acta, 2001. 1528 (2-3): p. 61-73.
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Magnadottir, B., et al., The carbohydrate moiety of serum IgM from Atlantic cod (Gadus morhua L.).
Fish Shellfish Immunol, 2002. 12 (3): p. 209-27.
Harvey, D.J., et al., "Internal residue loss": rearrangements occurring during the fragmentation of carbohydrates derivatized at the reducing terminus.
Anal Chem, 2002.
74 (4): p. 734-40.
Ritchie, G.E., et al., Glycosylation and the complement system.
Chem Rev, 2002. 102 (2): p.
305-20-19.
Wheeler, S.F., et al., Comparison of the N-linked glycans from soluble and GPI-anchored
CD59 expressed in CHO cells.
Glycobiology, 2002. 12 (4): p. 261-71.
Royle, L., et al., An analytical and structural database provides a strategy for sequencing Oglycans from microgram quantities of glycoproteins.
Anal Biochem, 2002. 304 (1): p. 70-90.
Merry, A.H., et al., Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis.
Anal Biochem, 2002. 304 (1): p. 91-9.
Saphire, E.O., et al., Contrasting IgG structures reveal extreme asymmetry and flexibility.
J
Mol Biol, 2002. 319 (1): p. 9-18.
Scanlan, C.N., et al., The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.
J Virol, 2002. 76 (14): p. 7306-21.
Rudd, P.M., et al., Glycosylation and prion protein.
Curr Opin Struct Biol, 2002. 12 (5): p.
578-86.
Radcliffe, C.M., et al., Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57.
J Biol Chem, 2002. 277 (48): p.
46415-23.
Navazio, L., et al., Monitoring endoplasmic reticulum-to-Golgi traffic of a plant calreticulin by protein glycosylation analysis.
Biochemistry, 2002. 41 (48): p. 14141-9.
Van den Steen, P.E., et al., Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9).
Crit Rev Biochem Mol Biol, 2002. 37 (6): p. 375-536.
Peracaula, R., et al., Glycosylation of human pancreatic ribonuclease: differences between normal and tumor states.
Glycobiology, 2003. 13 (4): p. 227-44.
Kim, S., et al., Structural determination of the N-glycans of a lepidopteran arylphorin reveals the presence of a monoglucosylated oligosaccharide in the storage protein.
Glycobiology,
2003. 13 (3): p. 147-57.
Peracaula, R., et al., Altered glycosylation pattern allows the distinction between prostatespecific antigen (PSA) from normal and tumor origins.
Glycobiology, 2003. 13 (6): p. 457-70.
Merry, A.H., et al., O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8.
J Biol Chem, 2003. 278 (29): p. 27119-28.
Royle, L., et al., Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems.
J Biol Chem, 2003. 278 (22): p. 20140-53.
Butler, M., et al., Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis.
Glycobiology, 2003. 13 (9): p. 601-22.
Scanlan, C.N., et al., The carbohydrate epitope of the neutralizing anti-HIV-1 antibody
2G12.
Adv Exp Med Biol, 2003. 535 : p. 205-18.
Lukacik, P., et al., Complement regulation at the molecular level: the structure of decayaccelerating factor.
Proc Natl Acad Sci U S A, 2004. 101 (5): p. 1279-84.
Ko, K., et al., Function and glycosylation of plant-derived antiviral monoclonal antibody.
Proc Natl Acad Sci U S A, 2003. 100 (13): p. 8013-8.
Calarese, D.A., et al., Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science, 2003. 300 (5628): p. 2065-71.
Saphire, E.O., et al., Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.
Adv Exp Med Biol, 2003. 535 : p. 55-66.
Lee, H.K., et al., Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.
Angew Chem Int Ed Engl,
2004. 43 (8): p. 1000-3.
Tekoah, Y., et al., Controlled glycosylation of therapeutic antibodies in plants.
Arch
Biochem Biophys, 2004. 426 (2): p. 266-78.
Wearsch, P.A., et al., Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status.
J Biol Chem, 2004. 279 (24): p. 25112-21.
Crispin, M.D., et al., Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure.
FEBS Lett, 2004. 566 (1-
3): p. 270-4.
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Khalaila, I., et al., Structural characterization of the N-glycan moiety and site of glycosylation in vitellogenin from the decapod crustacean Cherax quadricarinatus.
Glycobiology, 2004. 14 (9): p. 767-74.
Rudd, P.M., M.R. Wormald, and R.A. Dwek, Sugar-mediated ligand-receptor interactions in the immune system.
Trends Biotechnol, 2004. 22 (10): p. 524-30.
Tian, G., et al., Inhibition of alpha-glucosidases I and II increases the cell surface expression of functional class A macrophage scavenger receptor (SR-A) by extending its half-life.
J Biol Chem, 2004. 279 (38): p. 39303-9.
Arnold, J.N., et al., The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin.
J Immunol,
2004. 173 (11): p. 6831-40.
Omtvedt, L.A., et al., Artefacts formed by addition of urea to N-linked glycans released with peptide-N-glycosidase F for analysis by mass spectrometry.
Rapid Commun Mass
Spectrom, 2004. 18 (19): p. 2357-9.
O'Leary, J.M., et al., Identification and removal of O-linked and non-covalently linked sugars from recombinant protein produced using Pichia pastoris.
Protein Expr Purif, 2004. 38 (2): p.
217-27.
Jorgensen-Tye, B., et al., Epitope recognition of antibodies that define the sialomucin, 89.
90.
91.
92.
93.
94.
95. endolyn (CD164), a negative regulator of haematopoiesis.
Tissue Antigens, 2005. 65 (3): p.
220-39.
Jerkovic, L., et al., Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression.
J Proteome Res, 2005. 4 (3): p. 889-99.
Zajonc, D.M., et al., Molecular mechanism of lipopeptide presentation by CD1a.
Immunity,
2005. 22 (2): p. 209-19.
Arnold, J.N., et al., Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin.
J Biol Chem, 2005. 280 (32): p. 29080-7.
Su, Y., et al., Glycosylation influences the lectin activities of the macrophage mannose receptor.
J Biol Chem, 2005. 280 (38): p. 32811-20.
Zitzmann, N., et al., Glycosylation: disease targets and therapy.
Adv Exp Med Biol, 2005.
564 : p. 1-2.
Scanlan, C., et al., Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design.
Adv Exp Med Biol, 2005. 564 : p. 7-8.
Su, Y.R., et al., Glycosylation influences the ligand binding activities of mannose receptor.
96.
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Adv Exp Med Biol, 2005. 564 : p. 25-6.
Arnold, J.N., et al., Human immunoglobulin glycosylation and the lectin pathway of complement activation.
Adv Exp Med Biol, 2005. 564 : p. 27-43.
Shore, D.A., et al., Glycosylation and the function of the T cell co-receptor CD8.
Adv Exp
99.
Med Biol, 2005. 564 : p. 71-84.
Mimura, Y., et al., Immunogenicity of calreticulin-bound murine leukemia virus glycoprotein gp90.
Adv Exp Med Biol, 2005. 564 : p. 85-94.
100. Fry, S.A., et al., Differential glycosylation of gelatinase B from neutrophils and breast cancer cells.
Adv Exp Med Biol, 2005. 564 : p. 103-12.
101. Tabares, G., et al., Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
Glycobiology, 2006. 16 (2): p. 132-45.
102. Van den Steen, P.E., et al., The hemopexin and O-glycosylated domains tune gelatinase
B/MMP-9 bioavailability via inhibition and binding to cargo receptors.
J Biol Chem, 2006.
281 (27): p. 18626-37.
103. Doores, K.J., et al., Direct deprotected glycosyl-asparagine ligation.
Chem Commun
(Camb), 2006(13): p. 1401-3.
104. Webber, D., et al., Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation.
Febs J, 2006.
273 (13): p. 3024-37.
105. Jacquemin, M., et al., Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.
J Thromb Haemost, 2006. 4 (5): p. 1047-55.
106. Opdenakker, G., et al., Remnant epitopes, autoimmunity and glycosylation.
Biochim
Biophys Acta, 2006. 1760 (4): p. 610-5.
107. Arnold, J.N., et al., Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family?
J Biol
Chem, 2006. 281 (11): p. 6955-63.
108. Shore, D.A., et al., Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.
J Mol Biol, 2006.
358 (2): p. 347-54.
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109. Kim, Y.G., et al., The identification and characterization of xenoantigenic nonhuman carbohydrate sequences in membrane proteins from porcine kidney.
Proteomics, 2006.
6 (4): p. 1133-42.
110. Royle, L., et al., Detailed structural analysis of N-glycans released from glycoproteins in
SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions.
Methods Mol Biol, 2006. 347 : p. 125-43.
111. Rudd, P.M. and R.A. Dwek, Editorial overview - Structural glycobiology in medicine:
Carbohydrates and glycoconjuates.
Current opinion in structural biology, 2006. 16 : p. 559-
560.
112. Bardor, M., et al., Analytical strategies to investigate plant N-glycan profiles in the context of plant-made pharmaceuticals.
Curr Opin Struct Biol, 2006. 16 (5): p. 576-83.
113. Jayachandran, R., et al., Oligosaccharides modulate the apoptotic activity of glycodelin.
Glycobiology, 2006. 16 (11): p. 1052-63.
114. Crispin, M., et al., Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway.
Glycobiology, 2006. 16 (8): p. 748-56.
115. Wopereis, S., et al., Abnormal glycosylation with hypersialylated O-glycans in patients with
Sialuria.
Biochim Biophys Acta, 2006. 1762 (6): p. 598-607.
116. Rudd, P.M. and R.A. Dwek, Glycobiology and medicine.
The Biochemist, 2006. 28 (3): p.
18-21.
117. Omtvedt, L.A., et al., Glycan analysis of monoclonal antibodies secreted in deposition disorders indicates that subsets of plasma cells differentially process IgG glycans.
Arthritis
Rheum, 2006. 54 (11): p. 3433-40.
118. Arnold, J.N., et al., Mannan binding lectin and its interaction with immunoglobulins in health and in disease.
Immunol Lett, 2006. 106 (2): p. 103-10.
119. Fry, S.A., et al., Cancer-Associated Glycoforms of Gelatinase B Exhibit a Decreased Level of Binding to Galectin-3.
Biochemistry, 2006. 45 (51): p. 15249-15258.
120. Tsiftsoglou, S.A., et al., Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides.
Biochim Biophys Acta, 2006. 1764 (11): p.
1757-66.
121. Oortwijn, B.D., et al., Differential glycosylation of polymeric and monomeric IgA: a possible role in glomerular inflammation in IgA nephropathy.
J Am Soc Nephrol, 2006. 17 (12): p.
3529-39.
122. Robijn, M.L., et al., Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody.
Mol Biochem Parasitol, 2007. 151 (2): p.
148-61.
123. Barrabes, S., et al., Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer.
Glycobiology,
2007. 17 (4): p. 388-400.
124. Wada, Y., et al., Comparison of the methods for profiling glycoprotein glycans--HUPO
Human Disease Glycomics/Proteome Initiative multi-institutional study.
Glycobiology, 2007.
17 (4): p. 411-22.
125. Radcliffe, C.M., et al., Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.
J Biol Chem, 2007. 282 (10): p. 7405-15.
126. Block, T.M., et al., Glycobiology - discovery, diagnostics and drugs , in Glycobiology , C.
Sansom and O. Markman, Editors. 2007, Scion publishing Limited. p. 8 - 11.
127. Mimura, Y., et al., Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing.
Proc Natl Acad Sci U S A, 2007. 104 (14): p. 5983-
8.
128. Arnold, J.N., et al., The Impact of Glycosylation on the Biological Function and Structure of
Human Immunoglobulins.
Annu Rev Immunol, 2007. 25 : p. 21-50.
129. Sanchez, O., et al., The goat mammary glandular epithelial (GMGE) cell line promotes polyfucosylation and N,N'-diacetyllactosediaminylation of N-glycans linked to recombinant human erythropoietin.
Arch Biochem Biophys, 2007. 464 (2): p. 322-34.
130. Scanlan, C.N., et al., Inhibition of Mammalian Glycan Biosynthesis Produces Non-self
Antigens for a Broadly Neutralising, HIV-1 Specific Antibody.
J Mol Biol, 2007. 372 (1): p.
16-22.
131. Domann, P.J., et al., Separation-based Glycoprofiling Approaches using Fluorescent
Labels.
Proteomics, 2007. 7 Suppl 1 : p. 70-6.
132. Saldova, R., et al., Ovarian Cancer is Associated with Changes in Glycosylation in Both
Acute-Phase Proteins and IgG.
Glycobiology, 2007. 17 (12): p. 1344-56.
133. Gornik, O., et al., Changes of serum glycans during sepsis and acute pancreatitis.
Glycobiology, 2007. 17 (12): p. 1321-32.
6
134. Royle, L., et al., HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software.
Anal Biochem, 2007.
135. Brooks, S.A., et al., Altered glycosylation of proteins in cancer: what is the potential for new anti-tumour strategies.
Anticancer Agents Med Chem, 2008. 8 (1): p. 2-21.
136. Packer, N.H., et al., Frontiers in glycomics: Bioinformatics and biomarkers in disease An
NIH White Paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11-13, 2006).
Proteomics, 2008. 8 (1): p. 8-20.
EDITORIALS
Glycoconjugate Journal: (Assistant to the Advisory Editor)
Glycopinion Column: Bi-monthly Editorials (1991-1993) to the following papers:
1. Evaluation of Recombinant Proteins: Ken Seamon
2. Automation of Glycosylation Analysis: Raj Parekh
3. Will Complex Carbohydrate Ligands of Vascular Selectins be the next Generation of
Non-Steroidal Anti-Inflammatory Drugs?: Jeffrey Winklehake
4. Glycosylation in Parasitic Protozoa of the Trypanosomatid Family: Susanne Zamze
5. The Role of Mass Spectrometry in Glycobiology: David Harvey
6. Viral Glycoprotein Heterogeneity-Enhancment of Functional Diversity: Irene Schultze
and Ian Manger
7. Ganglioside GM1 and Sphingolipid breakdown Products in Cellular Proliferation and Signal
Transduction Pathways: Ana Olivera and Sarah Spiegel
8. Inositol Acylation of Glycophosphatidylinositol Membrane Anchors: Mark Field
9. Mucous Glycoproteins, Super Glycoforms: how to solve a Sticky Problem: Tony Corfield
10. Glycosylation of Pituitary Hormones: A Necessary and Multistep Control of Biopotency:
Catherine Ronin
11. The Biology of Glycoconjugates: Minoru Fukuda
12. Neural Glycoproteins : Do they provide specific clues for our understanding of glycan
functions? David Wing
13. The Glycosylation of antibody molecules: functional significance: Roy Jeffries
BOOK REVIEWS:
1. 1993 Glycoconjugates from A-Z: P.M. Rudd. Trends in Biotechnology 11, 313-314
Review of Glycoconjugates ed. H.J. Allen and A.C. Kisailus, Marcel Dekker (1992)
2. 1998 Society for General Microbiology Web page and ref….
Glycoanalysis Protocols Ed. E.F. Hounsell (Methods in Molecular Biology vol 76)
3. 2002 Introduction to Functional & Molecular Glycobiology Susan A. Brooks, Miriam V.
Dwek & Udo Schumacher (Bios Ltd)
COURSES/MEETINGS ORGANISED:
1. 1992 EMBO Course: Glycoprotein Analysis, Glycobiology Institute, Oxford
2. 1993 'Glycoprotein Analysis' University of Bialystok Medical School, Poland.
Combined Glycobiology Institute/ Oxford Glycosystems Workshop.
3. 1994 EMBO Course: Advanced Technologies for Oligosaccharide Analysis.
Glycobiology Institute, Oxford
4. 1996-2000 Annual D.Phil Induction Course: Biochemistry Department, Oxford
5. 1998-2005 host for Rodney Porter Memorial lectures (given by Dr. John Walker, Dr John
Gurdon, Dr. Richard Lerner, Dr. Stanley Prusiner, Prof. Andrew McMichael, Prof. Paul
Nurse, Prof. Stanley Prusiner)
6. 2002 Organising committee Jenner 6 Glycobiology and Medicine Seillac, France
7. 2004 Organising committee Jenner 7 Glycobiology and Medicine Oxford, UK
8. 2004 Organising committee FEBS Satellite meeting Glycoproteomics Dubrovnik, Croatia
7
Invited lectures
1. 1989 Weizmann Institute of Science, Israel
2. 1989 Soroka Medical School, Beersheva, Israel
3. 1992 Beckman Instruments Seminar Series, Oxford
4. 1992 Monsanto Corporation, St. Louis
5. 1992 Genentech Corporation, San Francisco
6. 1992 Beckman Instruments, Fullerton, USA
7. 1992 Organic Chemistry Group, Open University, Milton Keynes
8. 1993 Oxford Glycosystems European Seminar Series: London, Heidleburg, Basle, Paris,
9. Copenhagen
10. 1993 London Hospital Medical School (Dept. of Immunology)
11. 1993 University of Gdansk Medical School, Poland
12. 1993 Inaugural lecture at the Foundation of the Biotechnology Faculty, University of Gdansk
13. Medical School, Poland
14. 1993 Institute of Cellular and Molecular Biology, Chang-Gung Medical College, Taiwan
15. 1993 Nippon Shinyaku Co., Ltd, Tokyo, Japan
16. 1993 Kinki University, Osaka, Japan
17. 1993 Hong Kong University of Science and Technology
18. 1993 Bristol Immunology Group
19. 1994 London Hospital Medical School
20. 1994 Bristol Royal Infirmary
21. 1995 Introductory lecture: Glycotechnology Today (OGS workshop) University College,
London
22. 1995 Organic Chemistry Group, Open University, Milton Keynes
23. 1995 Cellular Immunology Unit, Sir William Dunn School of Pathology, Oxford
24. 1996 Wlodzimierz Mozolowski Memorial Lecture, Gdansk, Poland
25. 1996 German Biochemical Society, Leipzig, East Germany
26. 1997 Bristol University Medical School
27. 1997 SmithKline Beecham Inauguration of DITC/BBSRC grant
28. 1998 Prion group, Dept. of Neurobiology UCSF, USA
29. 1998 Viral Hepatitis Group Jefferson Medical College, Philadelphia, USA
30. 1998 SmithKline Beecham: Current status : DITC/BBSRC grant
31. 1998 Cellular Nutrition Research Group, Dept. of Biochemistry, Oxford
32. 1998 Max-Planck Institute for Molecular Genetics, Berlin
33. 1998 Glycobiology Institute, Oxford
34. 1999 The Scripps Research Institute, La Jolla CA USA
35. 1999 Glycobiology Institute, Oxford
36. 1999 McGill University, Montreal
37. 1999 Shanghai Medical University, PRC (2 lectures)
38. 1999 Fudan University, Department of Biochemistry
39. 1999 Beijing Medical University, PRC
40. 1999 St. George's Medical School, London
41. Institute for Animal Health, Compton
42. 2000 Western Oregon University
43. St Mary's College, Marago, CA
44. 2000 University of San Francisco
45. University of Kiev, Ukraine
46. 2000 University of Dniepropetrovsk, Ukraine
47. 2001 Thomas Jefferson University (Hepatitis Foundation Institute Delaware Valley College)
48. 2001 UC Davis California USA
49. 2001 The Scripps Research Institute
50. 2001 Celltech Ltd., UK
51. 2001 Glyko Ltd workshop, Imperial College of Science and Technology, University of
London
52. 2001 Ben Gurion University of the Negev (2 lectures)
53. 2 001 St. Mary’s Hospital, Paddington
54. 2001 Immunology Seminar Series, University of Cambridge
55. 2001 Department of Nephrology, DP3, Leiden University Medical Center, The Netherlands
56. 2001 Institute of Medical Biology and Human Genetics, University of Innsbruck, Austria
57. 2002 University of Cardiff Medical School
58. 2002 University of Girona, Spain
59. 2002 Polish Academy of Sciences, Centre of Excellence in Molecular Biotechnology,
Warsaw
60. 2002 University of Harvard Medical School, Boston
8
61. 2002 Okayama University Medical School, Japan
62. 2002 Oxford Virology Group
63. 2003 University of Oxford Virology Group
64. 2003 International University of Florida
65. 2003 University of Cambridge Virology Group
66. 2003 Celltech Ltd., UK
67. 2003 University of Grodno, Bellarus
68. 2004 School of Biological Sciences, University of Canterbury, New Zealand
69. 2004 NZ Society of Chemistry
70. 2004 University of Wellington NZ Biological Sciences Deptl. Seminar
71. 2004 Massey University Palmerston North NZ Dept Biochemistry
72. 2004 University of Auckland Dept Biochemistry
73. 2004 University of Otago, Dept Biochemistry
74. 2005 University of Girona
75. 2005 Singapore Bioprocessing Technology Institute
76. 2005 University of Craiova
77. 2005 University of Leiden
78. 2006 University of Utrecht
79. 2006 University of Newcastle
80. 2006 Biotech University, Avula, India
81. 2006 Shire Pharmaceuticals lunch meeting
82. 2006 Dublin City University Future
TCD
Invited papers given at Conferences
1. 1990 First Jenner International Workshop: Glycosylation and Rheumatoid Arthritis, Bristol,
UK
2. 1992 Fourth International Conference on High Performance Capillary Electrophoresis,
Amsterdam
3. 1992 International Biotechnology Expo and Scientific Conference, SF USA
4. 1993 Perspectives on protein engineering symposium (LINK), Oxford
5. 1993 British Electrophoresis Society Annual Conference
6. 1994 Protein Engineering Conference, Oxford
7. Chair for Session: Glycoprotein Structure and Function
8. 1994 Third Jenner International GlycoImmunology Meeting
9. 1996 4th Jenner International GlycoImmunology Meeting
10. 1997 EC Platform: Carbohydrate Engineering, Lisbon
11. 1997 Carbohydrate Bioengineering Conference, La Rochelle
12. 1997 Royal Flemish Chemical Society Symposium on Glycobiology
13. 1997 British Biochemical Society Meeting, Dundee
14. 1997 XIVth International Symposium on Glycoconjugates, Zurich
15. 1998 Biochemistry Department Research Staff Seminar Day
16. 1998 The Scientific Instrument Association Conference, London
17. 1998 EC Platform: Carbohydrate Engineering, Oulu, Finland
18. 1998 Structural Immunology Conference, Sweden
19. 1998 Protein Society (Methods in Protein Structural Analysis), Halkidiki, Greece
20. 1998 Polish Biochemical Society, Bialystok, Guest lecture
21. 1998 Romanian Biochemical Society
22. 1999 BSI meeting-Oxford Immunology Group T lymphocytes- Structure and Function
23. 1999 XVth International Symposium on Glycoconjugates, Tokyo
24. 1999 FEBS advanced course, Opatije, Croatia
25. 1999 European Commission Pharmacopia Conference, Strasbourg
26. 2000 Fairchild Review Meeting Prion protein UCSF CA USA
27. 2000 Javitts Meeting Prion protein UCSF CA USA
28. 2000 Glycobiology and Medicine, Royal Society of Medicine, London: 2 presentations
29. 2000 Plenary lecture HS Sequencing Project Workshop, 2000, Berlin
30. 2000 Plenary lecture British Electrophoresis Society, 2000, York
31. 2000 Lectins and Carbohydrates Conference, Brussels
32. 2000 Molecular Chaperone Club, 11th Meeting University of Oxford
33. 2000 British Electrophoresis Society, International meeting on Proteomics, York
34. 2000 Glyco XVI The Hague, The Netherlands
35. 2000 Munich Proteomics conference
36. 2001 Ben Gurion University, Israel
37. 2001 San Francisco Annual Glycobiology conference
9
38. 2001 Society of Chemical Industry, London
39. 2001 Invited meeting, The Scripps Research Institute, Indian Wells, CA
40. 2001 International Union of Biochemistry and Molecular Biology, Bergen
41. 2001 First Croatian Congress on Molecular Life sciences, Opatija
42. 2001 Polysaccharide conference, Nottingham
43. 2001 Jenner 6, Seillac, France
44. 2002 Glycobiology Conference, Boston
45. 2002 The Mitzutani International Symposium on Glycoscience to celebrate 10 th anniversary of Foundation, Tokyo, Japan
46. 2003 5 th Comparative Immunology Symposium Florida International University (Plenary lecture)
47. 2003 Royal Society of Chemistry Bracknell
48. 2004 ESACT conference Granada
49. 2004 ICES Proteomics meeting Glasgow
50. 2003 Havana Biotechnolgy conference
51. 2003 Havana AIDS workshop
52. 2003 FEBS meeting Kiev
53. 2003 Oslo Biochemistry Society
54. 2004 3rd International conference on recombinant antibodies, Munich
55. 2004 Biochem. Soc. Glasgow
56. 2004 Jenner Sept 4-8
57. 2004 Rega Institute 50 th anniversary
58. 2004 IBC conference Washington post-translational modifications
59. 2004 15th Joint Meeting Netherlands Society for Glycobiology Wageningen
60. 2004 Joint vaccine meeting, Eijkman graduate school, Utrecht
61. 2005 Consortium for Congenital Disorders of Glycosylation, Athens
62. 2005 Consortium for functional genomics NIH Bethesda USA
63. 2005 FEBS Satellite meeting Glycoproteomics Dubrovnik, Croatia
64. 2005 GlycoXVIII Florence
65. 2005 Glycobiology Satellite technology meeting Boston
66. 2005 Glycobiology main meeting Boston
67. 2005 BSI Harrogate
68. 2006 Glycobiology meeting Indian Institutes of Science, Bangalore
69. 2006 SBNet Tallberg Sweden
70. 2006 Tsukuba City Glycosyl transferases
71. 2006 International Proteomics meeting Hinxton Cambridge
72. 2006 Cancer glycosylated biomarkers conference, NCI Frederick, US
73. 2006 Cancer diagnostics workshop NIH Bethesda Washington US
74. 2006 Cancer biomarkers conference, Conway Institute, Dublin
75. 2006 Shire Annual meeting DYNEPO® Scientific Global Workshop, 30–31 October 2006
Future
Euroscion
Lyons antibody conference
Vincents
Workshops/conferences
1. 1995 EC project: Eurocarb workshop, GlycoImmunology, Dublin
2. 1996 4th Jenner International GlycoImmunology Meeting:
3. 1997 EC project: O-linked glycans. Three workshops Oxford, Copenhagen, Zurich
4. 1998 EC workshop, Oulu
5. 1998 EC workshop, Julich
6. 1999 Gordon Conference, Ventura, CA USA
7. 1999 Round Table Discussions EU platform with China
8. 2000 Chairman discussion section Internet conference on Carbohydrates
9. 2000 Invited meeting, The Scripps Research Institute, Indian Wells, CA
10. 2001 Gordon Conference, Ventura, CA USA
11. 2005 Eurocarb data base consortium, Heidelberg
12. 2006 Hinxton Eurocarb DB
13. 2006 Cancer diagnostics workshop NIH Bethesda Washington US (Session and workshop chair)
Lectures given at taught courses
10
1. 1992 EMBO Course: Glycoprotein Analysis, Oxford
2. 1992 Short Course in Glycobiology: Continuing Professional Development, Oxford
3. 1993 Glycobiology workshop: Bialystok Medical School, Poland
4. 1993 Glycobiology Course & Examination for Master's Degree & Continuing
Professional Education. Inst.e of Biochemical Sciences, National Taiwan University
5. 1994 Summer School Glycobiology Course: Gdansk University Biotechnology
Faculty
6. 1994 EMBO Course: Advanced Technologies for Oligosaccharide Analysis, Oxford
7. 1995 Summer School Gdansk University Biotechnology Faculty
8. 1996 Summer School Gdansk University Biotechnology Faculty
9. 1997 2nd Year Undergraduate lectures
10. 1997 Romanian Academy (2 lectures) An Introduction to Glycobiology
11. 1997 FEBS course (Hatfield) Protein Engineering
12. 1997 Summer School: Gdansk University Biotechnology Faculty
13. 1998 2nd Year Undergraduate lectures An Introduction to Glycobiology
14. 1999 2nd Year Undergraduate lectures An Introduction to Glycobiology
15. 1999 FEBS Advanced Course, Opatije, Croatia
16. 2000 2nd Year Undergraduate lectures An Introduction to Glycobiology
17. 2000 Western Oregon University
18. 2000 St Mary's College, Marago, CA
19. 2000 Seminars at University of San Franscisco CA
20. 2001 Wellcome prize students lecture course
21. 2001 FEBS Advanced Course, Dubrovnik, Croatia
22. 2002 3rd Year Undergraduate lectures An Introduction to Glycobiology
23. 2002 Undergraduate lecture University of Girona, Spain
24. 2002 University of Oxford Wellcome prize students lecture
25. 2003 University of Oxford Part 2 lecture
26. 2003 University of Oxford Wellcome students lecture
27. 2004 University of Namur, Belgium MSc lecture course
28. 2004 University of Canterbury, NZ (4 th year course Medicinal Glycobiology)
29. 2004 University of Canterbury New Zealand (2nd year course Biotechnology)
Selection of Poster presentations
1. 1999 Gordon Conference Ventura The influence of Baculovirus-host cell interactions on N-glycosylation of a recombinant human protein. Joshi, L., Davis, T.R., Mattu, T.S.,
Rudd, P.M., Dwek, R.A., Shuler, M.L. and Wood, H.A.
2. 1999 XVth International Symposium on Glycoconjugates, Tokyo Van den Steen,
P., Rudd, P.M. and Opdenakker, G. The glycosylation of gelatinase B Glycoconjugate
J. 16 S20-21
3. 2000 TSE Workshop (BBSRC, MRC, Dept Health and MAFF) University of Keele .
Ritchie, M., McGill, A., Colominas, C., Wing, D.R., Rudd, P.M., Dwek, R.A. and Hope,
J. Characterisation of the N-linked glycans of the prion protein: 87V Scrapie in VM mice
4. 2000 18th International Congress of Biochemistry and Molecular Biology Innate
Immunity Satellite Meeting 21 July, 2000 Sim R.B., Tran, T., Royle, L., Merry, T.M.,
Rudd, P.M. The N- and O-glycosylation of C1 inhibitor.
5. 2000 Mucins in Health and disease (6th International workshop on carcinomaassociated mucins, July 29-August 2, 2000) Royle, L., Mattu., T.S., Murphy, N.,
Langridge, J., Harvey, D.J., Dwek, R.A. and Rudd, P.M. Rapid profiling and characterisation of mucin O-glycan pools by HPLC and LC/MS/MS
6. 2000 15th International Mass Spectrometry Conference, Barcelona. Ritchie, M.,
McGill, A., Colominas, C., Wing, D.R., Rudd, P.M., Dwek, R.A. and Hope, J.
Characterisation of the N-linked glycans of the prion protein.
7. 2000 International Lipoprotein Club, Tutzing, Germany Garner, B., Harvey, D.,
Royle, L., Rudd, P.M. Structural elucidation of the N- and O-glycans attached to
ApoB100.
8. 2001 Boston Glycobiology Conference Royle, L., Mattu., T.S., Murphy, N.,
Langridge, J., Harvey, D.J., Dwek, R.A. and Rudd, P.M. Rapid profiling and
11
characterisation of mucin O-glycan pools by HPLC and LC/MS/MS
9. 2001 Gordon Conference , Ventura, CA USA Royle, L., Mattu., T.S., Murphy, N.,
Langridge, J., Harvey, D.J., Dwek, R.A. and Rudd, P.M. Rapid profiling and characterisation of mucin O-glycan pools by HPLC and LC/MS/MS
10. 2001 72nd European Atherosclerosis Society Congress Garner, B., Harvey, D.,
Frischmann, M., Nigon, F., Chapman, M.J. and Rudd, P.M. Human Apolipoprotein B-
100 oligosaccharide structure is not altered in familial hypercholesterolaemia or noninsulin dependent diabetes
11. 2001 Gordon Conference, Ventura, CA USA Merry, T., Astrautsova, S., Brown, G.,
Ellis, T., Royle, L. and Rudd, P.M. New approaches to analysis of sulphated glycans
12. 2001 Recognition Events In Glycobiology 4th Electronic Glycoscience Meeting
A.H. Merry, S. Astrautsova, G. Brown, T. Ellis, L. Royle, P.M. Rudd New Approaches to the Sulphation Analysis of Glycans:
13. 2001 Glycoconjugate XVI New Approaches to the Analysis of Sulphated Glycans
T.S. Ellis, A.H. Merry, S. Astrautsova, L. Royle, P.M. Rudd and G. Brown.
14. 2001 Calcium-binding proteins and calcium function in health and disease
Cavalese,The Dolomites, Italy L. Navazio, M. Miuzzo, P. Mariani, L. Royle, T. Merry and
P.M. Rudd. Monitoring Endoplasmic Reticulum-To-Golgi Traffic Of A Plant Calreticulin
By Protein Glycosylation Analysis
15. 2002 European Life Scientist Organization L. Navazio, M. Miuzzo, B. Baldan, P.
Mariani, L. Royle, T. Merry and P.M. Rudd Glycan analysis of a plant calreticulin reveals the presence of complex carbohydrate chains.
16. 2002 Jenner 6 Y. Su, L. Martinez-Pomares, C.M. Radcliffe, L. Royle, D.J. Harvey, R. A.
Dwek, P.M. Rudd The glycosylation of mannose receptor and its multiple binding properties.
17. 2002 Jenner 6 S.A. Fry, L. Royle, R.A. Dwek and P.M. Rudd Sequencing O-glycans from breast tissue.
18. 2002 Jenner 6 Rapid profiling and characterisation of mucin O-glycan pools by
HPLC and LC/MS/MS Royle, L., Mattu., T.S., Murphy, N., Langridge, J., Harvey, D.J.,
Dwek, R.A. and Rudd, P.M.
19. 2002 Jenner 6 Inhibition of
-glucosidases I and II causes increased expression and activity of the class A macrophage scavenger receptor G. Tian, F.M. Platt,
R.A. Dwek, P.M. Rudd and N. Platt
20. 2002 Jenner 6 Detailed glycan analysis of serum glycoproteins from CDG patients indicates the specific enzyme defect, provides a diagnosis and an insight into pathogenesis A.J. Critchley, M. Butler, H. Carchon, H. F. Hebestreit, R.G.
Hibbert, P. Argibay, D.J. Harvey, R.A. Dwek, J. Jaeken and P.M. Rudd
21. 2002 Jenner 6 Structural analysis of glycosylation in the complement system
G.E. Ritchie, B.E. Moffat, R.B. Sim, B.P. Morgan, R.A. Dwek and P.M. Rudd
22. 2002 Jenner 6 Identification of specific glycoforms of MHC class I heavy chains indicates that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57. C.M. Radcliffe, G. Diedrich, D.J. Harvey,
R.A. Dwek, P.r Cresswell and P.M. Rudd
23. 2003 39th Biochemistry Contact Meeting, Geilo, Norway, Glycosylation Studies of Immunoglobulin Deposition Disorders L. A. Omtvedt, G.
Husby K. Sletten, L. Royle, C. Radcliffe, D. J. Harvey, R. A. Dwek, P. M. Rudd
12
24. 2003 International Symposium on Bioinspired Engineering, Technion, Israel
Glycan analysis of a plant derived Antiviral monoclonal antibody by
Oligosaccharide sequencing technology Tekoah, Y. Rudd, P.M., and Dwek, R.A.
25. 2004 10th International Symposium on Urolithiasis to be held in Hong Kong
Characterisation of N-Linked Glycans on Urinary Prothrombin Fragment 1 from
White and Black South Africans (2004) D.Webber, C.M. Radcliffe, A.H. Merry, A.L.
Rodgers, E.D. Sturrock, R.A. Dwek & P.M. Rudd
26. 2004 Complement meeting Hawaii (2004) Immunoglobulin Glycosylation: The
Search for MBL Binding Targets Arnold, J.N, Radcliffe, C.M., Royle, L., Dwek, R.A.,
Rudd, P.M. & Sim,R.B.
27. Post-Translational Modifications (PTMs): Maintaining Comparability and Managing
PTMs in Biological Manufacture. 07 - 08 Nov 2006 , Basel, Switzerland Validation of
Capillary Electrophoresis (CE)/ Liquid Chromatography (LC) /Mass Spectrometry
(MS) Coupled Methods for Improved Microheterogeneity Discrimination of
Glycoproteins P. J. Vickers, A. C. Pardos-Pardos, M. Quaglia, R. Jawad, D. L.
Fernandes, R. A. Gardener, D. I. R. Spencer, C. M. Radcliffe, L. Royle, P. M. Rudd, R.
A. Dwek, D. J. Harvey, A. Adams, A.S. McIntyre, C. Neususs, R. Brown. C. Jones.
Applicants
Project title
Funding agency
Applicants
PM Rudd et al
EuroCarb DB
EU
PM Rudd et al
338,584 €
Project title
Funding agency
GLYFDIS
EU
540K
Supervision of visitors
1. 1995 Dr. Kazuya Mori, Nippon Shinyaku Co. (Japan)
2. 1997 Dr. Mando Watson, St. Georges' Hospital, London
3. 1998 Philippe Van den Steen (University of Leuven)
4. 1998 Dr. Bergljot Magnadottir (University of Iceland, Reykjavík); RS grant
5. 1998 Dr. Lokesh Joshi (University of Cornell)
6. 1998 Ricardo Gutierrez Gallego (University of Utrecht); EU grant
7. 1998 Dr Regina Sattarova (University of Tashkent, Uzbequistan); RS grant
8. 1999 Dr. Olga Miroshnichenko (University of Kiev, Ukraine); RS grant
9. 1999 Steven Rodgers (Immunology Department, Haywards Heath Hospital)
10. 1999 Dr. Kim Sooyun (University of Korea)
11. 1999 Dr. Pru Bird - John Radcliffe Hospital
12. 2000 Mr. Mark Ritchie (Institute for Animal Health, Compton)
13. 2000 Dr. Bergljot Magnadottir (Unive rsity of Iceland, Reykjavík)
14. 2000 Beryl Moffat (MRC Unit, Dept. Biochemistry, Oxford
€
15. 2000 Nony Emmanuel (LFB, Paris)
16. 2000 Dr. Svetlana Astraucou (University of Grodno, Bellaruss) RS grant
17. 2000 Thuy Tran (University of Paris) Wellcome grant
18. 2000 Steven Rodgers (Immunology Department, Haywards Heath Hospital)
19. 2000 Dr. Lorella Navazio Dept. of Biology, University of Padova, Italy
20. 2000 Dr. Brett Garner: Wellcome Trust award (University of Wollongong, Australia)
21. 2000 Dr. Michael Butler (University of Manitoba) on sabbatical
22. 2001 Dr. Tian Dang (Xian Medical University): RS Royal Fellowship
23. 2001 Dr. Rosa Peracaula (Barcelona)
24. 2001 Dr. Irina Pimentiskya (Universityof Dniepropetrovsk, Ukraine)
25. 2001 Dr. Pablo Argibay (University of Buenos Aries, Argentina)
26. 2001 Manuela Miuzzo (University of Padua)
27. 2001 Monica Barclay (University of Manchester)
28. 2001 Britt Jorgensen (IMM)
29. 2002 Dr. Robert Boehm University of Bonn, Germany
13
30. 2002 Dr. Lone Omtvedt University of Oslo
31. 2002 Helen Bryant University of Bristol
32. 2002 Tracey Carter Brookes University, Oxford
33. 2002 Dr. Svetlana Astraucou (University of Grodno, Bellaruss) RS grant
34. 2002 Dr. Marjolein Robyn (University of Leiden)
35. 2002 Dr. Anja Roos (University of Leiden)
36. 2002 Dr. Y. Kimura (University of Okayama)
37. 2002 David Suter (University of Geneva)
38. 2002 Dr. Yoram Yedakh (Ben Gurion University, Israel)
39. 2003 Dr. Antonio Vallín García (Cuba)
40. 2003 Dawn Webber (University of Capetown)
41. 2003 Liz Matthews (University of Dublin)
42. 2004 Dr. Rosa Peracaula (University of Girona)
43. 2004 Dr. Sophie Richert (Serono Ltd)
44. 2004 Crina Paduara (University of Bucharest)
45. 2005 Dr. Yungon Kim (University of Seoul)
46. 2005 Dr. Jose Cremata (Biotech University, Cuba)
47. 2005 Dr. Sylvia Barrabes (University of Girona)
48. 2005 Claire
49. 2005 Sarah (Nottingham)
Co-supervisor (with Prof. R.A. Dwek) of students
Taj Mattu D.Phil
Peter Catellino M.Sc
Part 2 students
Gail Ritchie
Max Crispin
Manuela Miuzzo (Padova) Erasmus scheme
Chloe Tosevin
Gemma Tobiasen
Rachel Evans
Ben Sharpe
D.Phil. students
Su Yunpeng
David Shore
Chris Scanlan
Gail Ritchie
Max Crispin
Alison Critchley
Simon Fry
Maximilliano Jiminez (with Dr. Ian Wilson TSRI)
Huiping Ding (with Dr. Dennis Burton TSRI)
Karen Muindi (with Dr. M. Brenner, Harvard)
Crina Paduraru (with Dr. S. Petrescu, Bucharest and Dr. Peter Cresswell, Yale)
Stephanie Pollock (with Dr. Ian Wilson TSRI)
Jean Xu (with Dr. Dennis Burton TSRI)
Umi Hamid
Wellcome prize students:
Robin Schlinkert
Richard Hibbert
University Examining
1. 1998 - 2000 Oxford Biochemistry Department, Examiner Part 1
2. 1998 PhD Pauline Kemp (University of Canterbury, UK)
3. 1998 D.Phil. Transfer report Alpana Prasad (Dept. of Biochemistry, Oxford)
4. 2001 PhD Anna Hills (University of Canterbury)
5. 2001 PhD Philippe Van den Steen (University of Leuven)
6. 2001 PhD Fanning Zeng (University of Leeds)
7. 2002 DPhil transfer report Antu Dey
8. 2003 Oxford University examiner Biochemistry Part II
9. 2003 DPhil transfer report James Arnold
14
10. 2003 PhD Inge Nellison (University of Leuven)
11. 2004 DPhil transfer report Freddie Partridge
The Royal Society
Member of Panel of International Exchanges Committee covering the former Soviet Union
Public understanding of Science
Invited lectures:
1. 1990 General Studies Group: Headington School, Oxford
2. 1991 British Association of Young Scientists, Oxford
3. 1994 Sixth Form General Studies: St. Edward’s School, Oxford
4. 1994 Vale of the White Horse Deanery, Diocese of Oxford, Clergy Chapter
5. 1997 British Association of Young Scientists, Oxford
6. 1997/8 Centre for Theology and the Natural Sciences, University of Berkely,
California Participation in Three Workshops on Science and Religion:
7. 1997 Presentation: Science and Religion, CTNS, Berkeley, CA
8. 1998 Presentation: Science and Spirituality, CTNS, Berkeley, CA
9. 1998 Member of a Panel consisting of a Philoshopher, Psychologist, Theologian and Biochemist: Great Milton, Oxfordshire ’Knowing who you are’.
10. 1998 Theology Faculty, Postgraduate Seminar Oxford: Scientific method
11. 1998 Ian Ramsey Centre: respondent to lecture by Dr. J. Poulton Mitcohondrial
DNA: evolution and genetic counselling
12. 1998 Public conference Science and the Spiritual Quest, Berkeley, CA: Science and Spirituality
13. 1998 Advanced-level research conference for winners of the 1998 Templeton
Science and Religion course prize competition, Berkeley, CA.
14. 1998 Communi ty of St. Mary the Virgin, Wantage, Berks ‘Science and Spirituality’.
15. 1999 Undergraduate seminar on Biomedical ethics, Stanford University
16. 1999 Undergraduate seminar on Science and Religion, St. Mary’s College, Marago,
CA (Templeton Prize course, Prof. Ron Olowin)
17. 1999Undergraduate lecture, Caldwell College, Idaho (Templeton Prize course)
18. 1999 Public lecture, Caldwell College, Idaho (Templeton Prize course)
19. 1999 CTNS Public Forum, Berkeley
20. 1999 Theology Faculty, Oxford. Postgraduate Seminar (Templeton Prize course
21. 1999 Yeshiva University, New York (Templeton Prize course, Prof. Carl Feit)
22. 1999 Science and Religion course, Los Medanos College, CA (Templeton Prize course, Dr. Kate Boisvert)
23. 1999 Chautaqua Institution, New York State Opening lecture for 1999 season
24. 2000 Oxford University Sermon at St. Mary's: Religion and Science
25. 2000 Public Seminar at Western Oregon University Sc and Re course
26. 2000 Public Seminar at St Mary's College, Marago, CA Sc and Re course
27. 2000 University of San Francisco Public seminar Sc/Re course
28. 2000 Ian Ramsey Centre: respondent to lecture by Prof. Berj Bardakjian 'Cues of
Consciousness in Brain Cells
29. 2000 Venturfest: Talk on University spin off companies in ISIS section.
30. 2000 After Dinner Forum, State of the World Conference, New York
31. 2000 Seminar: Science, Intuition and Imagination, State of the World Conference,
New York
32. 2000 Seminar: Science, Altruism and Purpose, State of the World Conference,
New York
33. 2001 Co-chair SSQII Biological Sciences workshop, Universite Interdisciplinaire,
Paris
34. 2001 Theology Faculty Seminar, University of Oxford
35. 2001 New York: Public Conference at General Theological Seminary
36. 2001 Frontiers of Medicine: Human Genome-Human Being: London
37. 2001 Theology Faculty Seminar, University of Oxford
38. 2001 International symposium: Theology, Natural Sciences and Cultural Studies on
Resurrection Ruprecht-Karls-Universitat, Heidelberg
39. 2001 Introductory presentation in public conference with the Orthodox church on
Science and Religion, Bucharest, Romania
40. 2002 Ethics and Molecular Life Sciences in Technology, Medicine and Ecology, IC
London
41. 2002 Theology Faculty Ethics Seminar, University of Oxford
42. 2002 Universite Interdisciplinaire de Paris, Al Akhawayn University, Morocco
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43. 2002 Science and Spirit Summer Conference, Oxford
44. 2002 CS Lewis Seminar Series, Oxford
45. 2002 Chair Biology discussion section: SSQ conference, Granada, Spain
46. 2002 Fine tuning in the Universe St. George’s Windsor
47. 2002 Gakushuin University,Japan
48. 2002 Sermon at Mansfield College, Oxford
49. 2002 Ian Ramsey Centre, Oxford
50. 2003 M.Theol students, Oxford
51. 2004 University of Canterbury, Christchurch New approaches to anti-viral therapies
52. 2004 University of Canterbury, Christchurch Potential diagnostics for cancer
53. 2004 Bhaktivedanta Institute, Rome
54. 2005 Metanexus Institute, Philadelphia
55. 2005 Universitie Interdisciplinaire, Senlis, Paris
56. 2005 Bucharest and Constanza, Romania
57. 2006 Little Flower Seminary, Avula, India
58. 2006 Workshop on Creativity (Hirota) Kyoto
59. 2006 Meetings in ISSR Cambridge
60. 2006 GPSS meeting, Paris
Television
1. 2001 Central News (HIV)
2. 2001 Channel 4 News (Prions)
3. 2001 Channel 6 live (Prions)
4. 2001 French TV7 (Prions)
5. 2001 Romanian TV (Science and Religion)
6. 2002 Croatian TV (Glycosylation and immunity)
Radio
1. 1999 Chataqua local radio (Science and Religion)
2. 2001 Oxford radio (HIV b12 antibody; Science paper)
3. 2001 Fusion radio (HIV)
4. 2001 Fox FM (HIV)
5. 2001 Fusion radio (Prions D18 Fab, Nature paper)
6. 2001 Fox FM (Prions)
7. 2001 Sky radio News (Prions)
8. 2003 Oxford University students ’ radio
Prizes
2001 Templeton/ASA Prize for best video of a Science and Religion talk
PUS Publications:
1. Rapid Quantitative HPLC profiling of IgG glycans P.M. Rudd (1996) Oxford
GlycoSystems GlycoNews.
2. Release and enzymatic sequencing of human serum transferrin glycans Rudd, P.M.,
Iourin, O., Mattu, T.S., Guile, G.R. and Dwek, R.A. (1997) Oxford GlycoSystems
GlycoNews.
3. An automated strategy for carbohydrate sequencing OGS Technical bulletin 12
(1994) Resolution of glycoforms of RNase B by P/ACE Capillary Electrophoresis
PM. Rudd and E. Coghill Technical Information, Beckman (1993).
4. An automated strategy for carbohydrate sequencing P.M. Rudd OGS Technical
Bulletin 12 (1994).
5. Oligosaccharides in Biology P.M. Rudd Oxford Glycosystems GlycoNews Third (1993).
6. The Quest for God Rudd, P.M. (1989) Toc H Journal Point 3.
7. Science and the Spiritual Quest Rudd, P.M. (1997) CTNS Winter Bulletin 17 4 1-5.
8. The Science and Spiritual Quest Rudd, P.M. Science and Spirit Winter 1998-9 2-3.
9. Life the Universe and Everything - what is it for? Rudd, P.M. (2000) 189-191 God for the 21st century: Editor: Russell Stannard Templeton Press
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10. Mind the Light Rudd P.M. (2001) Metanexus web site.
11. Law, Chance and Opportunity in Nature: Insight into Natural and Human Creativity
Rudd P.M. (2001) Metanexus internet journal.
12. Science and the Spiritual Quest: New Essays by Leading
Scientists
Rudd, P.M. Editors Philip Clayton, et al., (London and New York:
Routledge, 2002).
13. Law, Chance and Opportunity Rudd, P.M. (2002) Proceedings
Romanian Academy.
14. Functional complexity in biology and religion (2005) Metanexus conference proceedings.
15. The proceedings of the Congress of October 2005, "Science and Orthodoxy, a Necessary
Dialogue", eds. Basarab Nicolescu and Magda Stavinschi, came out finally, besides two translations in Romanian: "When Science Meets Religion" by Ian Barbour and "Quarks,
Chaos and Christianity" by John Polkinghorne".
16. The Oxford Handbook of Religion and Science Eds Philip clayton and Zachary Simpson
OUP 2006 p 388-404
Membership of Boards and Learned Societies
Advisory Board of Ian Ramsay Centre, Oxford.
Elected member: International Society for Science and Religion
Global perpectives in Science and Spirituality: Judging panel for funding 2004, 2006
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