CURRICULUM VITAE - Bioinformatics

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CURRICULUM VITAE

Name: Pauline Mary Rudd PhD, MA (Oxon), B.Sc., L.R.I.C. Date of Birth: 17.09.42

Address: 29, Sadlers Court,

Abingdon, Oxon, OX14 2PA

Marah’s, Knockaphrumpa, Roundwood, Moneystown, Co Wicklow, Ireland

HIGHER EDUCATION

1961-1964 B.Sc. Special Chemistry Westfield College, University of London

1967 L.R.I.C. (Licentiate of the Royal Institute of Chemistry)

1995 Ph.D. The Open University, Milton Keynes

1998 MA Oxon

EXPERIENCE

1964-1969: Wessex Biochemicals/Sigma London: Founding Scientist, Senior Chemist

responsible for Research, Development and Production of sugars and sugar phosphates.

Restart of Career after bringing up 4 children:

1983-present Department of Biochemistry, University of Oxford

1983-1984: Research Technician, Glycobiology Institute

1984-1996: Post Graduate Research Assistant

1996- 2000 Senior Research Fellow

1996-present Head of GlycoImmunology group

1998-2000 University Research lecturer

2000-2006 University Reader in Glycobiology

Current position: NIBRT Professor of Glycoproteomics and Glycobiology at University College, Dublin

Other positions held concurrently:

1991-1993 Glycoconjugate Journal: Assistant to Advisory Editor

1991-present University Liason Officer for Technology Transfer to Oxford GlycoSciences

1993-2002 Consultant to Oxford GlycoSciences Ltd.

1996-1999 Biochemistry Departmental committee

1996-present: Senior Departmental Teaching Associate (Dept. of Biochemistry)

Co-Chair: Committee for organising Rodney Porter Annual Memorial Lecture

1996-2000 Chair: D.Phil. induction course and transferable skills courses

1998- present Scientific Advisory Board for Jenner bi-annual conferences

1998-1999 Visiting Research Associate, The Scripps Research Institute, La Jolla, CA

1999-2001 Visiting Professor of Biochemistry, Shanghai Medical University, PRC

2001 Visiting scientist Ben Gurion University of the Negev, Israel

2002 Elected Founder member: International Society for Science and Religion

2000- Committee member, Wellcome graduate student scheme

2002- 2005 Royal Society Committee for Grants for Eastern Europe

2003 Examiner Part 2, Biochemistry Department, Oxford University

2003-4 Scientific Advisory Board for FEBS course in Croatia (2004)

2000-3 Scientific Advisory Board for Immunology Programme, FIU,Miami

2004 Erskine Visiting Fellow, Canterbury University, Christchurch, New Zealand

Annual entry in Who’s Who in the World 1997-present

PUBLICATIONS

1. Wittwer, A.J., et al., Effects of N-glycosylation on in vitro activity of Bowes melanoma and

2. human colon fibroblast derived tissue plasminogen activator.

Biochemistry, 1989. 28 (19): p.

7662-9.

Parekh, R.B., et al., N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell

3. line.

Biochemistry, 1989. 28 (19): p. 7670-9.

Rudd, P.M., et al., Diversification of the IgG molecule by oligosaccharides.

Mol Immunol,

1991. 28 (12): p. 1369-78.

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Rudd, P.M., et al., Separation and analysis of the glycoform populations of ribonuclease B using capillary electrophoresis.

Glycoconj J, 1992. 9 (2): p. 86-91.

Opdenakker, G., et al., Concepts and principles of glycobiology.

Faseb J, 1993. 7 (14): p.

1330-7.

Field, M.C., et al., Structural analysis of the N-glycans from human immunoglobulin A1: comparison of normal human serum immunoglobulin A1 with that isolated from patients with rheumatoid arthritis.

Biochem J, 1994. 299 ( Pt 1) : p. 261-75.

Rudd, P.M., et al., Glycoforms modify the dynamic stability and functional activity of an enzyme.

Biochemistry, 1994. 33 (1): p. 17-22.

Rudd, P.M., et al., A human T-cell receptor recognizes 'O'-linked sugars from the hinge region of human IgA1 and IgD.

Immunology, 1994. 83 (1): p. 99-106.

Rudd, P.M., et al., The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator.

Biochim Biophys Acta, 1995.

1248 (1): p. 1-10.

Mori, K., et al., The activation of type 1 and type 2 plasminogen by type I and type II tissue plasminogen activator.

J Biol Chem, 1995. 270 (7): p. 3261-7.

Opdenakker, G., et al., Cells regulate the activities of cytokines by glycosylation.

Faseb J,

1995. 9 (5): p. 453-7.

Malhotra, R., et al., Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein.

Nat Med, 1995. 1 (3): p. 237-43.

Rudd, P., et al., Lectin-carbohydrate interactions in disease. T-cell recognition of IgA and

IgD; mannose binding protein recognition of IgG0.

Adv Exp Med Biol, 1995. 376 : p. 147-52.

Iourin, O., et al., The identification of abnormal glycoforms of serum transferrin in carbohydrate deficient glycoprotein syndrome type I by capillary zone electrophoresis.

Glycoconj J, 1996. 13 (6): p. 1031-42.

Guile, G.R., et al., A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles.

Anal Biochem, 1996.

240 (2): p. 210-26.

Zapun, A., et al., Conformation-independent binding of monoglucosylated ribonuclease B to calnexin.

Cell, 1997. 88 (1): p. 29-38.

Rudd, P.M., et al., The glycosylation of the complement regulatory protein, human erythrocyte CD59.

J Biol Chem, 1997. 272 (11): p. 7229-44.

Wormald, M.R., et al., Variations in oligosaccharide-protein interactions in immunoglobulin

G determine the site-specific glycosylation profiles and modulate the dynamic motion of the

Fc oligosaccharides.

Biochemistry, 1997. 36 (6): p. 1370-80.

Rudd, P.M. and R.A. Dwek, Glycosylation: heterogeneity and the 3D structure of proteins.

Crit Rev Biochem Mol Biol, 1997. 32 (1): p. 1-100.

Rudd, P.M. and R.A. Dwek, Rapid, sensitive sequencing of oligosaccharides from glycoproteins.

Curr Opin Biotechnol, 1997. 8 (4): p. 488-97.

Rudd, P.M., et al., Oligosaccharide sequencing technology.

Nature, 1997. 388 (6638): p.

205-7.

Mehta, A., et al., A strategy for anti-viral intervention: the use of alpha-glucosidase inhibitors to prevent chaperone-mediated folding of viral envelope glycoproteins.

Biochem Soc Trans,

1997. 25 (4): p. 1188-93.

Rudd, P.M., et al., Roles for glycosylation in the anti-inflammatory molecule CD59.

Biochem

Soc Trans, 1997. 25 (4): p. 1177-84.

Mattu, T.S., et al., The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fc alpha receptor interactions.

J Biol Chem,

1998. 273 (4): p. 2260-72.

Rudd, P.M., et al., The glycosylation of the complement regulatory protein, human erythrocyte CD59.

Adv Exp Med Biol, 1998. 435 : p. 153-62.

Hennet, T., et al., Genomic cloning and expression of three murine UDP-galactose: beta-Nacetylglucosamine beta1,3-galactosyltransferase genes.

J Biol Chem, 1998. 273 (1): p. 58-

65.

Roberts, D.B., et al., Mutant analysis reveals an alternative pathway for N-linked glycosylation in Drosophila melanogaster.

Eur J Biochem, 1998. 253 (2): p. 494-8.

Routier, F.H., et al., Quantitation of the oligosaccharides of human serum IgG from patients with rheumatoid arthritis: a critical evaluation of different methods.

J Immunol Methods,

1998. 213 (2): p. 113-30.

Van den Steen, P., et al., Concepts and principles of O-linked glycosylation.

Crit Rev

Biochem Mol Biol, 1998. 33 (3): p. 151-208.

Mehta, A., et al., Alpha-glucosidase inhibitors as potential broad based anti-viral agents.

FEBS Lett, 1998. 430 (1-2): p. 17-22.

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McAlister, M.S., et al., Structural analysis of the CD5 antigen--expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1.

Eur J Biochem, 1998. 257 (1): p. 131-41.

Van den Steen, P., et al., Oligosaccharides of recombinant mouse gelatinase B variants.

Biochim Biophys Acta, 1998. 1425 (3): p. 587-98.

Rudd, P.M., M.R. Wormald, and R.A. Dwek, Glycosylation and the immune system.

J

Protein Chem, 1998. 17 (6): p. 519.

Rudd, P.M., et al., Glycoproteins: rapid sequencing technology for N-linked and GPI anchor glycans.

Biotechnol Genet Eng Rev, 1999. 16 : p. 1-21.

Rudd, P.M., et al., Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells.

Glycobiology, 1999. 9 (5): p. 443-58.

Watson, M., et al., Sugar printing rheumatic diseases: a potential method for disease differentiation using immunoglobulin G oligosaccharides.

Arthritis Rheum, 1999. 42 (8): p.

1682-90.

Rudd, P.M., et al., Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.

Biochemistry, 1999. 38 (42): p. 13937-50.

Rudd, P.M., et al., Roles for glycosylation of cell surface receptors involved in cellular immune recognition.

J Mol Biol, 1999. 293 (2): p. 351-66.

Rudd, P.M., et al., Glycosylation differences between the normal and pathogenic prion protein isoforms.

Proc Natl Acad Sci U S A, 1999. 96 (23): p. 13044-9.

Martinez-Pomares, L., et al., Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor.

J Biol Chem, 1999.

274 (49): p. 35211-8.

Devasahayam, M., et al., The glycan processing and site occupancy of recombinant Thy-1 is markedly affected by the presence of a glycosylphosphatidylinositol anchor.

Glycobiology, 1999. 9 (12): p. 1381-7.

Rudd, P.M., et al., Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.

Biochemistry, 2000. 39 (7): p. 1596-603.

Garred, P., et al., Two edged role of mannose binding lectin in rheumatoid arthritis: a cross sectional study.

J Rheumatol, 2000. 27 (1): p. 26-34.

Zitzmann, N., et al., Protein structure controls the processing of the N-linked oligosaccharides and glycosylphosphatidylinositol glycans of variant surface glycoproteins expressed in bloodstream form Trypanosoma brucei.

Glycobiology, 2000. 10 (3): p. 243-9.

Joshi, L., et al., Influence of baculovirus-host cell interactions on complex N-linked glycosylation of a recombinant human protein.

Biotechnol Prog, 2000. 16 (4): p. 650-6.

Mattu, T.S., et al., O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme.

Biochemistry, 2000. 39 (51): p. 15695-704.

Rudd, P.M., et al., A high-performance liquid chromatography based strategy for rapid, sensitive sequencing of N-linked oligosaccharide modifications to proteins in sodium dodecyl sulphate polyacrylamide electrophoresis gel bands.

Proteomics, 2001. 1 (2): p. 285-

94.

Rudd, P.M., et al., Prion glycoprotein: structure, dynamics, and roles for the sugars.

Biochemistry, 2001. 40 (13): p. 3759-66.

Rudd, P.M., et al., Glycosylation and the immune system.

Science, 2001. 291 (5512): p.

2370-6.

Garner, B., et al., Structural elucidation of the N- and O-glycans of human apolipoprotein(a): role of o-glycans in conferring protease resistance.

J Biol Chem, 2001. 276 (25): p. 22200-8.

Rudd, P.M., G. Opdenakker, and R.A. Dwek, Holistic approaches to glycobiology.

Nat

Biotechnol, 2001. 19 (6): p. 531-2.

Garner, B., et al., Characterization of human apolipoprotein B100 oligosaccharides in LDL subfractions derived from normal and hyperlipidemic plasma: deficiency of alpha-Nacetylneuraminyllactosyl-ceramide in light and small dense LDL particles.

Glycobiology,

2001. 11 (10): p. 791-802.

Saphire, E.O., et al., Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.

Science, 2001. 293 (5532): p. 1155-9.

Peretz, D., et al., Antibodies inhibit prion propagation and clear cell cultures of prion infectivity.

Nature, 2001. 412 (6848): p. 739-43.

Van den Steen, P.E., et al., Matrix remodelling enzymes, the protease cascade and glycosylation.

Biochim Biophys Acta, 2001. 1528 (2-3): p. 61-73.

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Magnadottir, B., et al., The carbohydrate moiety of serum IgM from Atlantic cod (Gadus morhua L.).

Fish Shellfish Immunol, 2002. 12 (3): p. 209-27.

Harvey, D.J., et al., "Internal residue loss": rearrangements occurring during the fragmentation of carbohydrates derivatized at the reducing terminus.

Anal Chem, 2002.

74 (4): p. 734-40.

Ritchie, G.E., et al., Glycosylation and the complement system.

Chem Rev, 2002. 102 (2): p.

305-20-19.

Wheeler, S.F., et al., Comparison of the N-linked glycans from soluble and GPI-anchored

CD59 expressed in CHO cells.

Glycobiology, 2002. 12 (4): p. 261-71.

Royle, L., et al., An analytical and structural database provides a strategy for sequencing Oglycans from microgram quantities of glycoproteins.

Anal Biochem, 2002. 304 (1): p. 70-90.

Merry, A.H., et al., Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis.

Anal Biochem, 2002. 304 (1): p. 91-9.

Saphire, E.O., et al., Contrasting IgG structures reveal extreme asymmetry and flexibility.

J

Mol Biol, 2002. 319 (1): p. 9-18.

Scanlan, C.N., et al., The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

J Virol, 2002. 76 (14): p. 7306-21.

Rudd, P.M., et al., Glycosylation and prion protein.

Curr Opin Struct Biol, 2002. 12 (5): p.

578-86.

Radcliffe, C.M., et al., Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57.

J Biol Chem, 2002. 277 (48): p.

46415-23.

Navazio, L., et al., Monitoring endoplasmic reticulum-to-Golgi traffic of a plant calreticulin by protein glycosylation analysis.

Biochemistry, 2002. 41 (48): p. 14141-9.

Van den Steen, P.E., et al., Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9).

Crit Rev Biochem Mol Biol, 2002. 37 (6): p. 375-536.

Peracaula, R., et al., Glycosylation of human pancreatic ribonuclease: differences between normal and tumor states.

Glycobiology, 2003. 13 (4): p. 227-44.

Kim, S., et al., Structural determination of the N-glycans of a lepidopteran arylphorin reveals the presence of a monoglucosylated oligosaccharide in the storage protein.

Glycobiology,

2003. 13 (3): p. 147-57.

Peracaula, R., et al., Altered glycosylation pattern allows the distinction between prostatespecific antigen (PSA) from normal and tumor origins.

Glycobiology, 2003. 13 (6): p. 457-70.

Merry, A.H., et al., O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8.

J Biol Chem, 2003. 278 (29): p. 27119-28.

Royle, L., et al., Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems.

J Biol Chem, 2003. 278 (22): p. 20140-53.

Butler, M., et al., Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis.

Glycobiology, 2003. 13 (9): p. 601-22.

Scanlan, C.N., et al., The carbohydrate epitope of the neutralizing anti-HIV-1 antibody

2G12.

Adv Exp Med Biol, 2003. 535 : p. 205-18.

Lukacik, P., et al., Complement regulation at the molecular level: the structure of decayaccelerating factor.

Proc Natl Acad Sci U S A, 2004. 101 (5): p. 1279-84.

Ko, K., et al., Function and glycosylation of plant-derived antiviral monoclonal antibody.

Proc Natl Acad Sci U S A, 2003. 100 (13): p. 8013-8.

Calarese, D.A., et al., Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.

Science, 2003. 300 (5628): p. 2065-71.

Saphire, E.O., et al., Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.

Adv Exp Med Biol, 2003. 535 : p. 55-66.

Lee, H.K., et al., Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.

Angew Chem Int Ed Engl,

2004. 43 (8): p. 1000-3.

Tekoah, Y., et al., Controlled glycosylation of therapeutic antibodies in plants.

Arch

Biochem Biophys, 2004. 426 (2): p. 266-78.

Wearsch, P.A., et al., Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status.

J Biol Chem, 2004. 279 (24): p. 25112-21.

Crispin, M.D., et al., Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure.

FEBS Lett, 2004. 566 (1-

3): p. 270-4.

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Khalaila, I., et al., Structural characterization of the N-glycan moiety and site of glycosylation in vitellogenin from the decapod crustacean Cherax quadricarinatus.

Glycobiology, 2004. 14 (9): p. 767-74.

Rudd, P.M., M.R. Wormald, and R.A. Dwek, Sugar-mediated ligand-receptor interactions in the immune system.

Trends Biotechnol, 2004. 22 (10): p. 524-30.

Tian, G., et al., Inhibition of alpha-glucosidases I and II increases the cell surface expression of functional class A macrophage scavenger receptor (SR-A) by extending its half-life.

J Biol Chem, 2004. 279 (38): p. 39303-9.

Arnold, J.N., et al., The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin.

J Immunol,

2004. 173 (11): p. 6831-40.

Omtvedt, L.A., et al., Artefacts formed by addition of urea to N-linked glycans released with peptide-N-glycosidase F for analysis by mass spectrometry.

Rapid Commun Mass

Spectrom, 2004. 18 (19): p. 2357-9.

O'Leary, J.M., et al., Identification and removal of O-linked and non-covalently linked sugars from recombinant protein produced using Pichia pastoris.

Protein Expr Purif, 2004. 38 (2): p.

217-27.

Jorgensen-Tye, B., et al., Epitope recognition of antibodies that define the sialomucin, 89.

90.

91.

92.

93.

94.

95. endolyn (CD164), a negative regulator of haematopoiesis.

Tissue Antigens, 2005. 65 (3): p.

220-39.

Jerkovic, L., et al., Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression.

J Proteome Res, 2005. 4 (3): p. 889-99.

Zajonc, D.M., et al., Molecular mechanism of lipopeptide presentation by CD1a.

Immunity,

2005. 22 (2): p. 209-19.

Arnold, J.N., et al., Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin.

J Biol Chem, 2005. 280 (32): p. 29080-7.

Su, Y., et al., Glycosylation influences the lectin activities of the macrophage mannose receptor.

J Biol Chem, 2005. 280 (38): p. 32811-20.

Zitzmann, N., et al., Glycosylation: disease targets and therapy.

Adv Exp Med Biol, 2005.

564 : p. 1-2.

Scanlan, C., et al., Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design.

Adv Exp Med Biol, 2005. 564 : p. 7-8.

Su, Y.R., et al., Glycosylation influences the ligand binding activities of mannose receptor.

96.

97.

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Adv Exp Med Biol, 2005. 564 : p. 25-6.

Arnold, J.N., et al., Human immunoglobulin glycosylation and the lectin pathway of complement activation.

Adv Exp Med Biol, 2005. 564 : p. 27-43.

Shore, D.A., et al., Glycosylation and the function of the T cell co-receptor CD8.

Adv Exp

99.

Med Biol, 2005. 564 : p. 71-84.

Mimura, Y., et al., Immunogenicity of calreticulin-bound murine leukemia virus glycoprotein gp90.

Adv Exp Med Biol, 2005. 564 : p. 85-94.

100. Fry, S.A., et al., Differential glycosylation of gelatinase B from neutrophils and breast cancer cells.

Adv Exp Med Biol, 2005. 564 : p. 103-12.

101. Tabares, G., et al., Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.

Glycobiology, 2006. 16 (2): p. 132-45.

102. Van den Steen, P.E., et al., The hemopexin and O-glycosylated domains tune gelatinase

B/MMP-9 bioavailability via inhibition and binding to cargo receptors.

J Biol Chem, 2006.

281 (27): p. 18626-37.

103. Doores, K.J., et al., Direct deprotected glycosyl-asparagine ligation.

Chem Commun

(Camb), 2006(13): p. 1401-3.

104. Webber, D., et al., Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation.

Febs J, 2006.

273 (13): p. 3024-37.

105. Jacquemin, M., et al., Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.

J Thromb Haemost, 2006. 4 (5): p. 1047-55.

106. Opdenakker, G., et al., Remnant epitopes, autoimmunity and glycosylation.

Biochim

Biophys Acta, 2006. 1760 (4): p. 610-5.

107. Arnold, J.N., et al., Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family?

J Biol

Chem, 2006. 281 (11): p. 6955-63.

108. Shore, D.A., et al., Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.

J Mol Biol, 2006.

358 (2): p. 347-54.

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109. Kim, Y.G., et al., The identification and characterization of xenoantigenic nonhuman carbohydrate sequences in membrane proteins from porcine kidney.

Proteomics, 2006.

6 (4): p. 1133-42.

110. Royle, L., et al., Detailed structural analysis of N-glycans released from glycoproteins in

SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions.

Methods Mol Biol, 2006. 347 : p. 125-43.

111. Rudd, P.M. and R.A. Dwek, Editorial overview - Structural glycobiology in medicine:

Carbohydrates and glycoconjuates.

Current opinion in structural biology, 2006. 16 : p. 559-

560.

112. Bardor, M., et al., Analytical strategies to investigate plant N-glycan profiles in the context of plant-made pharmaceuticals.

Curr Opin Struct Biol, 2006. 16 (5): p. 576-83.

113. Jayachandran, R., et al., Oligosaccharides modulate the apoptotic activity of glycodelin.

Glycobiology, 2006. 16 (11): p. 1052-63.

114. Crispin, M., et al., Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway.

Glycobiology, 2006. 16 (8): p. 748-56.

115. Wopereis, S., et al., Abnormal glycosylation with hypersialylated O-glycans in patients with

Sialuria.

Biochim Biophys Acta, 2006. 1762 (6): p. 598-607.

116. Rudd, P.M. and R.A. Dwek, Glycobiology and medicine.

The Biochemist, 2006. 28 (3): p.

18-21.

117. Omtvedt, L.A., et al., Glycan analysis of monoclonal antibodies secreted in deposition disorders indicates that subsets of plasma cells differentially process IgG glycans.

Arthritis

Rheum, 2006. 54 (11): p. 3433-40.

118. Arnold, J.N., et al., Mannan binding lectin and its interaction with immunoglobulins in health and in disease.

Immunol Lett, 2006. 106 (2): p. 103-10.

119. Fry, S.A., et al., Cancer-Associated Glycoforms of Gelatinase B Exhibit a Decreased Level of Binding to Galectin-3.

Biochemistry, 2006. 45 (51): p. 15249-15258.

120. Tsiftsoglou, S.A., et al., Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides.

Biochim Biophys Acta, 2006. 1764 (11): p.

1757-66.

121. Oortwijn, B.D., et al., Differential glycosylation of polymeric and monomeric IgA: a possible role in glomerular inflammation in IgA nephropathy.

J Am Soc Nephrol, 2006. 17 (12): p.

3529-39.

122. Robijn, M.L., et al., Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody.

Mol Biochem Parasitol, 2007. 151 (2): p.

148-61.

123. Barrabes, S., et al., Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer.

Glycobiology,

2007. 17 (4): p. 388-400.

124. Wada, Y., et al., Comparison of the methods for profiling glycoprotein glycans--HUPO

Human Disease Glycomics/Proteome Initiative multi-institutional study.

Glycobiology, 2007.

17 (4): p. 411-22.

125. Radcliffe, C.M., et al., Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.

J Biol Chem, 2007. 282 (10): p. 7405-15.

126. Block, T.M., et al., Glycobiology - discovery, diagnostics and drugs , in Glycobiology , C.

Sansom and O. Markman, Editors. 2007, Scion publishing Limited. p. 8 - 11.

127. Mimura, Y., et al., Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing.

Proc Natl Acad Sci U S A, 2007. 104 (14): p. 5983-

8.

128. Arnold, J.N., et al., The Impact of Glycosylation on the Biological Function and Structure of

Human Immunoglobulins.

Annu Rev Immunol, 2007. 25 : p. 21-50.

129. Sanchez, O., et al., The goat mammary glandular epithelial (GMGE) cell line promotes polyfucosylation and N,N'-diacetyllactosediaminylation of N-glycans linked to recombinant human erythropoietin.

Arch Biochem Biophys, 2007. 464 (2): p. 322-34.

130. Scanlan, C.N., et al., Inhibition of Mammalian Glycan Biosynthesis Produces Non-self

Antigens for a Broadly Neutralising, HIV-1 Specific Antibody.

J Mol Biol, 2007. 372 (1): p.

16-22.

131. Domann, P.J., et al., Separation-based Glycoprofiling Approaches using Fluorescent

Labels.

Proteomics, 2007. 7 Suppl 1 : p. 70-6.

132. Saldova, R., et al., Ovarian Cancer is Associated with Changes in Glycosylation in Both

Acute-Phase Proteins and IgG.

Glycobiology, 2007. 17 (12): p. 1344-56.

133. Gornik, O., et al., Changes of serum glycans during sepsis and acute pancreatitis.

Glycobiology, 2007. 17 (12): p. 1321-32.

6

134. Royle, L., et al., HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software.

Anal Biochem, 2007.

135. Brooks, S.A., et al., Altered glycosylation of proteins in cancer: what is the potential for new anti-tumour strategies.

Anticancer Agents Med Chem, 2008. 8 (1): p. 2-21.

136. Packer, N.H., et al., Frontiers in glycomics: Bioinformatics and biomarkers in disease An

NIH White Paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11-13, 2006).

Proteomics, 2008. 8 (1): p. 8-20.

EDITORIALS

Glycoconjugate Journal: (Assistant to the Advisory Editor)

Glycopinion Column: Bi-monthly Editorials (1991-1993) to the following papers:

1. Evaluation of Recombinant Proteins: Ken Seamon

2. Automation of Glycosylation Analysis: Raj Parekh

3. Will Complex Carbohydrate Ligands of Vascular Selectins be the next Generation of

Non-Steroidal Anti-Inflammatory Drugs?: Jeffrey Winklehake

4. Glycosylation in Parasitic Protozoa of the Trypanosomatid Family: Susanne Zamze

5. The Role of Mass Spectrometry in Glycobiology: David Harvey

6. Viral Glycoprotein Heterogeneity-Enhancment of Functional Diversity: Irene Schultze

and Ian Manger

7. Ganglioside GM1 and Sphingolipid breakdown Products in Cellular Proliferation and Signal

Transduction Pathways: Ana Olivera and Sarah Spiegel

8. Inositol Acylation of Glycophosphatidylinositol Membrane Anchors: Mark Field

9. Mucous Glycoproteins, Super Glycoforms: how to solve a Sticky Problem: Tony Corfield

10. Glycosylation of Pituitary Hormones: A Necessary and Multistep Control of Biopotency:

Catherine Ronin

11. The Biology of Glycoconjugates: Minoru Fukuda

12. Neural Glycoproteins : Do they provide specific clues for our understanding of glycan

functions? David Wing

13. The Glycosylation of antibody molecules: functional significance: Roy Jeffries

BOOK REVIEWS:

1. 1993 Glycoconjugates from A-Z: P.M. Rudd. Trends in Biotechnology 11, 313-314

Review of Glycoconjugates ed. H.J. Allen and A.C. Kisailus, Marcel Dekker (1992)

2. 1998 Society for General Microbiology Web page and ref….

Glycoanalysis Protocols Ed. E.F. Hounsell (Methods in Molecular Biology vol 76)

3. 2002 Introduction to Functional & Molecular Glycobiology Susan A. Brooks, Miriam V.

Dwek & Udo Schumacher (Bios Ltd)

COURSES/MEETINGS ORGANISED:

1. 1992 EMBO Course: Glycoprotein Analysis, Glycobiology Institute, Oxford

2. 1993 'Glycoprotein Analysis' University of Bialystok Medical School, Poland.

Combined Glycobiology Institute/ Oxford Glycosystems Workshop.

3. 1994 EMBO Course: Advanced Technologies for Oligosaccharide Analysis.

Glycobiology Institute, Oxford

4. 1996-2000 Annual D.Phil Induction Course: Biochemistry Department, Oxford

5. 1998-2005 host for Rodney Porter Memorial lectures (given by Dr. John Walker, Dr John

Gurdon, Dr. Richard Lerner, Dr. Stanley Prusiner, Prof. Andrew McMichael, Prof. Paul

Nurse, Prof. Stanley Prusiner)

6. 2002 Organising committee Jenner 6 Glycobiology and Medicine Seillac, France

7. 2004 Organising committee Jenner 7 Glycobiology and Medicine Oxford, UK

8. 2004 Organising committee FEBS Satellite meeting Glycoproteomics Dubrovnik, Croatia

7

Invited lectures

1. 1989 Weizmann Institute of Science, Israel

2. 1989 Soroka Medical School, Beersheva, Israel

3. 1992 Beckman Instruments Seminar Series, Oxford

4. 1992 Monsanto Corporation, St. Louis

5. 1992 Genentech Corporation, San Francisco

6. 1992 Beckman Instruments, Fullerton, USA

7. 1992 Organic Chemistry Group, Open University, Milton Keynes

8. 1993 Oxford Glycosystems European Seminar Series: London, Heidleburg, Basle, Paris,

9. Copenhagen

10. 1993 London Hospital Medical School (Dept. of Immunology)

11. 1993 University of Gdansk Medical School, Poland

12. 1993 Inaugural lecture at the Foundation of the Biotechnology Faculty, University of Gdansk

13. Medical School, Poland

14. 1993 Institute of Cellular and Molecular Biology, Chang-Gung Medical College, Taiwan

15. 1993 Nippon Shinyaku Co., Ltd, Tokyo, Japan

16. 1993 Kinki University, Osaka, Japan

17. 1993 Hong Kong University of Science and Technology

18. 1993 Bristol Immunology Group

19. 1994 London Hospital Medical School

20. 1994 Bristol Royal Infirmary

21. 1995 Introductory lecture: Glycotechnology Today (OGS workshop) University College,

London

22. 1995 Organic Chemistry Group, Open University, Milton Keynes

23. 1995 Cellular Immunology Unit, Sir William Dunn School of Pathology, Oxford

24. 1996 Wlodzimierz Mozolowski Memorial Lecture, Gdansk, Poland

25. 1996 German Biochemical Society, Leipzig, East Germany

26. 1997 Bristol University Medical School

27. 1997 SmithKline Beecham Inauguration of DITC/BBSRC grant

28. 1998 Prion group, Dept. of Neurobiology UCSF, USA

29. 1998 Viral Hepatitis Group Jefferson Medical College, Philadelphia, USA

30. 1998 SmithKline Beecham: Current status : DITC/BBSRC grant

31. 1998 Cellular Nutrition Research Group, Dept. of Biochemistry, Oxford

32. 1998 Max-Planck Institute for Molecular Genetics, Berlin

33. 1998 Glycobiology Institute, Oxford

34. 1999 The Scripps Research Institute, La Jolla CA USA

35. 1999 Glycobiology Institute, Oxford

36. 1999 McGill University, Montreal

37. 1999 Shanghai Medical University, PRC (2 lectures)

38. 1999 Fudan University, Department of Biochemistry

39. 1999 Beijing Medical University, PRC

40. 1999 St. George's Medical School, London

41. Institute for Animal Health, Compton

42. 2000 Western Oregon University

43. St Mary's College, Marago, CA

44. 2000 University of San Francisco

45. University of Kiev, Ukraine

46. 2000 University of Dniepropetrovsk, Ukraine

47. 2001 Thomas Jefferson University (Hepatitis Foundation Institute Delaware Valley College)

48. 2001 UC Davis California USA

49. 2001 The Scripps Research Institute

50. 2001 Celltech Ltd., UK

51. 2001 Glyko Ltd workshop, Imperial College of Science and Technology, University of

London

52. 2001 Ben Gurion University of the Negev (2 lectures)

53. 2 001 St. Mary’s Hospital, Paddington

54. 2001 Immunology Seminar Series, University of Cambridge

55. 2001 Department of Nephrology, DP3, Leiden University Medical Center, The Netherlands

56. 2001 Institute of Medical Biology and Human Genetics, University of Innsbruck, Austria

57. 2002 University of Cardiff Medical School

58. 2002 University of Girona, Spain

59. 2002 Polish Academy of Sciences, Centre of Excellence in Molecular Biotechnology,

Warsaw

60. 2002 University of Harvard Medical School, Boston

8

61. 2002 Okayama University Medical School, Japan

62. 2002 Oxford Virology Group

63. 2003 University of Oxford Virology Group

64. 2003 International University of Florida

65. 2003 University of Cambridge Virology Group

66. 2003 Celltech Ltd., UK

67. 2003 University of Grodno, Bellarus

68. 2004 School of Biological Sciences, University of Canterbury, New Zealand

69. 2004 NZ Society of Chemistry

70. 2004 University of Wellington NZ Biological Sciences Deptl. Seminar

71. 2004 Massey University Palmerston North NZ Dept Biochemistry

72. 2004 University of Auckland Dept Biochemistry

73. 2004 University of Otago, Dept Biochemistry

74. 2005 University of Girona

75. 2005 Singapore Bioprocessing Technology Institute

76. 2005 University of Craiova

77. 2005 University of Leiden

78. 2006 University of Utrecht

79. 2006 University of Newcastle

80. 2006 Biotech University, Avula, India

81. 2006 Shire Pharmaceuticals lunch meeting

82. 2006 Dublin City University Future

TCD

Invited papers given at Conferences

1. 1990 First Jenner International Workshop: Glycosylation and Rheumatoid Arthritis, Bristol,

UK

2. 1992 Fourth International Conference on High Performance Capillary Electrophoresis,

Amsterdam

3. 1992 International Biotechnology Expo and Scientific Conference, SF USA

4. 1993 Perspectives on protein engineering symposium (LINK), Oxford

5. 1993 British Electrophoresis Society Annual Conference

6. 1994 Protein Engineering Conference, Oxford

7. Chair for Session: Glycoprotein Structure and Function

8. 1994 Third Jenner International GlycoImmunology Meeting

9. 1996 4th Jenner International GlycoImmunology Meeting

10. 1997 EC Platform: Carbohydrate Engineering, Lisbon

11. 1997 Carbohydrate Bioengineering Conference, La Rochelle

12. 1997 Royal Flemish Chemical Society Symposium on Glycobiology

13. 1997 British Biochemical Society Meeting, Dundee

14. 1997 XIVth International Symposium on Glycoconjugates, Zurich

15. 1998 Biochemistry Department Research Staff Seminar Day

16. 1998 The Scientific Instrument Association Conference, London

17. 1998 EC Platform: Carbohydrate Engineering, Oulu, Finland

18. 1998 Structural Immunology Conference, Sweden

19. 1998 Protein Society (Methods in Protein Structural Analysis), Halkidiki, Greece

20. 1998 Polish Biochemical Society, Bialystok, Guest lecture

21. 1998 Romanian Biochemical Society

22. 1999 BSI meeting-Oxford Immunology Group T lymphocytes- Structure and Function

23. 1999 XVth International Symposium on Glycoconjugates, Tokyo

24. 1999 FEBS advanced course, Opatije, Croatia

25. 1999 European Commission Pharmacopia Conference, Strasbourg

26. 2000 Fairchild Review Meeting Prion protein UCSF CA USA

27. 2000 Javitts Meeting Prion protein UCSF CA USA

28. 2000 Glycobiology and Medicine, Royal Society of Medicine, London: 2 presentations

29. 2000 Plenary lecture HS Sequencing Project Workshop, 2000, Berlin

30. 2000 Plenary lecture British Electrophoresis Society, 2000, York

31. 2000 Lectins and Carbohydrates Conference, Brussels

32. 2000 Molecular Chaperone Club, 11th Meeting University of Oxford

33. 2000 British Electrophoresis Society, International meeting on Proteomics, York

34. 2000 Glyco XVI The Hague, The Netherlands

35. 2000 Munich Proteomics conference

36. 2001 Ben Gurion University, Israel

37. 2001 San Francisco Annual Glycobiology conference

9

38. 2001 Society of Chemical Industry, London

39. 2001 Invited meeting, The Scripps Research Institute, Indian Wells, CA

40. 2001 International Union of Biochemistry and Molecular Biology, Bergen

41. 2001 First Croatian Congress on Molecular Life sciences, Opatija

42. 2001 Polysaccharide conference, Nottingham

43. 2001 Jenner 6, Seillac, France

44. 2002 Glycobiology Conference, Boston

45. 2002 The Mitzutani International Symposium on Glycoscience to celebrate 10 th anniversary of Foundation, Tokyo, Japan

46. 2003 5 th Comparative Immunology Symposium Florida International University (Plenary lecture)

47. 2003 Royal Society of Chemistry Bracknell

48. 2004 ESACT conference Granada

49. 2004 ICES Proteomics meeting Glasgow

50. 2003 Havana Biotechnolgy conference

51. 2003 Havana AIDS workshop

52. 2003 FEBS meeting Kiev

53. 2003 Oslo Biochemistry Society

54. 2004 3rd International conference on recombinant antibodies, Munich

55. 2004 Biochem. Soc. Glasgow

56. 2004 Jenner Sept 4-8

57. 2004 Rega Institute 50 th anniversary

58. 2004 IBC conference Washington post-translational modifications

59. 2004 15th Joint Meeting Netherlands Society for Glycobiology Wageningen

60. 2004 Joint vaccine meeting, Eijkman graduate school, Utrecht

61. 2005 Consortium for Congenital Disorders of Glycosylation, Athens

62. 2005 Consortium for functional genomics NIH Bethesda USA

63. 2005 FEBS Satellite meeting Glycoproteomics Dubrovnik, Croatia

64. 2005 GlycoXVIII Florence

65. 2005 Glycobiology Satellite technology meeting Boston

66. 2005 Glycobiology main meeting Boston

67. 2005 BSI Harrogate

68. 2006 Glycobiology meeting Indian Institutes of Science, Bangalore

69. 2006 SBNet Tallberg Sweden

70. 2006 Tsukuba City Glycosyl transferases

71. 2006 International Proteomics meeting Hinxton Cambridge

72. 2006 Cancer glycosylated biomarkers conference, NCI Frederick, US

73. 2006 Cancer diagnostics workshop NIH Bethesda Washington US

74. 2006 Cancer biomarkers conference, Conway Institute, Dublin

75. 2006 Shire Annual meeting DYNEPO® Scientific Global Workshop, 30–31 October 2006

Future

Euroscion

Lyons antibody conference

Vincents

Workshops/conferences

1. 1995 EC project: Eurocarb workshop, GlycoImmunology, Dublin

2. 1996 4th Jenner International GlycoImmunology Meeting:

3. 1997 EC project: O-linked glycans. Three workshops Oxford, Copenhagen, Zurich

4. 1998 EC workshop, Oulu

5. 1998 EC workshop, Julich

6. 1999 Gordon Conference, Ventura, CA USA

7. 1999 Round Table Discussions EU platform with China

8. 2000 Chairman discussion section Internet conference on Carbohydrates

9. 2000 Invited meeting, The Scripps Research Institute, Indian Wells, CA

10. 2001 Gordon Conference, Ventura, CA USA

11. 2005 Eurocarb data base consortium, Heidelberg

12. 2006 Hinxton Eurocarb DB

13. 2006 Cancer diagnostics workshop NIH Bethesda Washington US (Session and workshop chair)

Lectures given at taught courses

10

1. 1992 EMBO Course: Glycoprotein Analysis, Oxford

2. 1992 Short Course in Glycobiology: Continuing Professional Development, Oxford

3. 1993 Glycobiology workshop: Bialystok Medical School, Poland

4. 1993 Glycobiology Course & Examination for Master's Degree & Continuing

Professional Education. Inst.e of Biochemical Sciences, National Taiwan University

5. 1994 Summer School Glycobiology Course: Gdansk University Biotechnology

Faculty

6. 1994 EMBO Course: Advanced Technologies for Oligosaccharide Analysis, Oxford

7. 1995 Summer School Gdansk University Biotechnology Faculty

8. 1996 Summer School Gdansk University Biotechnology Faculty

9. 1997 2nd Year Undergraduate lectures

10. 1997 Romanian Academy (2 lectures) An Introduction to Glycobiology

11. 1997 FEBS course (Hatfield) Protein Engineering

12. 1997 Summer School: Gdansk University Biotechnology Faculty

13. 1998 2nd Year Undergraduate lectures An Introduction to Glycobiology

14. 1999 2nd Year Undergraduate lectures An Introduction to Glycobiology

15. 1999 FEBS Advanced Course, Opatije, Croatia

16. 2000 2nd Year Undergraduate lectures An Introduction to Glycobiology

17. 2000 Western Oregon University

18. 2000 St Mary's College, Marago, CA

19. 2000 Seminars at University of San Franscisco CA

20. 2001 Wellcome prize students lecture course

21. 2001 FEBS Advanced Course, Dubrovnik, Croatia

22. 2002 3rd Year Undergraduate lectures An Introduction to Glycobiology

23. 2002 Undergraduate lecture University of Girona, Spain

24. 2002 University of Oxford Wellcome prize students lecture

25. 2003 University of Oxford Part 2 lecture

26. 2003 University of Oxford Wellcome students lecture

27. 2004 University of Namur, Belgium MSc lecture course

28. 2004 University of Canterbury, NZ (4 th year course Medicinal Glycobiology)

29. 2004 University of Canterbury New Zealand (2nd year course Biotechnology)

Selection of Poster presentations

1. 1999 Gordon Conference Ventura The influence of Baculovirus-host cell interactions on N-glycosylation of a recombinant human protein. Joshi, L., Davis, T.R., Mattu, T.S.,

Rudd, P.M., Dwek, R.A., Shuler, M.L. and Wood, H.A.

2. 1999 XVth International Symposium on Glycoconjugates, Tokyo Van den Steen,

P., Rudd, P.M. and Opdenakker, G. The glycosylation of gelatinase B Glycoconjugate

J. 16 S20-21

3. 2000 TSE Workshop (BBSRC, MRC, Dept Health and MAFF) University of Keele .

Ritchie, M., McGill, A., Colominas, C., Wing, D.R., Rudd, P.M., Dwek, R.A. and Hope,

J. Characterisation of the N-linked glycans of the prion protein: 87V Scrapie in VM mice

4. 2000 18th International Congress of Biochemistry and Molecular Biology Innate

Immunity Satellite Meeting 21 July, 2000 Sim R.B., Tran, T., Royle, L., Merry, T.M.,

Rudd, P.M. The N- and O-glycosylation of C1 inhibitor.

5. 2000 Mucins in Health and disease (6th International workshop on carcinomaassociated mucins, July 29-August 2, 2000) Royle, L., Mattu., T.S., Murphy, N.,

Langridge, J., Harvey, D.J., Dwek, R.A. and Rudd, P.M. Rapid profiling and characterisation of mucin O-glycan pools by HPLC and LC/MS/MS

6. 2000 15th International Mass Spectrometry Conference, Barcelona. Ritchie, M.,

McGill, A., Colominas, C., Wing, D.R., Rudd, P.M., Dwek, R.A. and Hope, J.

Characterisation of the N-linked glycans of the prion protein.

7. 2000 International Lipoprotein Club, Tutzing, Germany Garner, B., Harvey, D.,

Royle, L., Rudd, P.M. Structural elucidation of the N- and O-glycans attached to

ApoB100.

8. 2001 Boston Glycobiology Conference Royle, L., Mattu., T.S., Murphy, N.,

Langridge, J., Harvey, D.J., Dwek, R.A. and Rudd, P.M. Rapid profiling and

11

characterisation of mucin O-glycan pools by HPLC and LC/MS/MS

9. 2001 Gordon Conference , Ventura, CA USA Royle, L., Mattu., T.S., Murphy, N.,

Langridge, J., Harvey, D.J., Dwek, R.A. and Rudd, P.M. Rapid profiling and characterisation of mucin O-glycan pools by HPLC and LC/MS/MS

10. 2001 72nd European Atherosclerosis Society Congress Garner, B., Harvey, D.,

Frischmann, M., Nigon, F., Chapman, M.J. and Rudd, P.M. Human Apolipoprotein B-

100 oligosaccharide structure is not altered in familial hypercholesterolaemia or noninsulin dependent diabetes

11. 2001 Gordon Conference, Ventura, CA USA Merry, T., Astrautsova, S., Brown, G.,

Ellis, T., Royle, L. and Rudd, P.M. New approaches to analysis of sulphated glycans

12. 2001 Recognition Events In Glycobiology 4th Electronic Glycoscience Meeting

A.H. Merry, S. Astrautsova, G. Brown, T. Ellis, L. Royle, P.M. Rudd New Approaches to the Sulphation Analysis of Glycans:

13. 2001 Glycoconjugate XVI New Approaches to the Analysis of Sulphated Glycans

T.S. Ellis, A.H. Merry, S. Astrautsova, L. Royle, P.M. Rudd and G. Brown.

14. 2001 Calcium-binding proteins and calcium function in health and disease

Cavalese,The Dolomites, Italy L. Navazio, M. Miuzzo, P. Mariani, L. Royle, T. Merry and

P.M. Rudd. Monitoring Endoplasmic Reticulum-To-Golgi Traffic Of A Plant Calreticulin

By Protein Glycosylation Analysis

15. 2002 European Life Scientist Organization L. Navazio, M. Miuzzo, B. Baldan, P.

Mariani, L. Royle, T. Merry and P.M. Rudd Glycan analysis of a plant calreticulin reveals the presence of complex carbohydrate chains.

16. 2002 Jenner 6 Y. Su, L. Martinez-Pomares, C.M. Radcliffe, L. Royle, D.J. Harvey, R. A.

Dwek, P.M. Rudd The glycosylation of mannose receptor and its multiple binding properties.

17. 2002 Jenner 6 S.A. Fry, L. Royle, R.A. Dwek and P.M. Rudd Sequencing O-glycans from breast tissue.

18. 2002 Jenner 6 Rapid profiling and characterisation of mucin O-glycan pools by

HPLC and LC/MS/MS Royle, L., Mattu., T.S., Murphy, N., Langridge, J., Harvey, D.J.,

Dwek, R.A. and Rudd, P.M.

19. 2002 Jenner 6 Inhibition of

-glucosidases I and II causes increased expression and activity of the class A macrophage scavenger receptor G. Tian, F.M. Platt,

R.A. Dwek, P.M. Rudd and N. Platt

20. 2002 Jenner 6 Detailed glycan analysis of serum glycoproteins from CDG patients indicates the specific enzyme defect, provides a diagnosis and an insight into pathogenesis A.J. Critchley, M. Butler, H. Carchon, H. F. Hebestreit, R.G.

Hibbert, P. Argibay, D.J. Harvey, R.A. Dwek, J. Jaeken and P.M. Rudd

21. 2002 Jenner 6 Structural analysis of glycosylation in the complement system

G.E. Ritchie, B.E. Moffat, R.B. Sim, B.P. Morgan, R.A. Dwek and P.M. Rudd

22. 2002 Jenner 6 Identification of specific glycoforms of MHC class I heavy chains indicates that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57. C.M. Radcliffe, G. Diedrich, D.J. Harvey,

R.A. Dwek, P.r Cresswell and P.M. Rudd

23. 2003 39th Biochemistry Contact Meeting, Geilo, Norway, Glycosylation Studies of Immunoglobulin Deposition Disorders L. A. Omtvedt, G.

Husby K. Sletten, L. Royle, C. Radcliffe, D. J. Harvey, R. A. Dwek, P. M. Rudd

12

24. 2003 International Symposium on Bioinspired Engineering, Technion, Israel

Glycan analysis of a plant derived Antiviral monoclonal antibody by

Oligosaccharide sequencing technology Tekoah, Y. Rudd, P.M., and Dwek, R.A.

25. 2004 10th International Symposium on Urolithiasis to be held in Hong Kong

Characterisation of N-Linked Glycans on Urinary Prothrombin Fragment 1 from

White and Black South Africans (2004) D.Webber, C.M. Radcliffe, A.H. Merry, A.L.

Rodgers, E.D. Sturrock, R.A. Dwek & P.M. Rudd

26. 2004 Complement meeting Hawaii (2004) Immunoglobulin Glycosylation: The

Search for MBL Binding Targets Arnold, J.N, Radcliffe, C.M., Royle, L., Dwek, R.A.,

Rudd, P.M. & Sim,R.B.

27. Post-Translational Modifications (PTMs): Maintaining Comparability and Managing

PTMs in Biological Manufacture. 07 - 08 Nov 2006 , Basel, Switzerland Validation of

Capillary Electrophoresis (CE)/ Liquid Chromatography (LC) /Mass Spectrometry

(MS) Coupled Methods for Improved Microheterogeneity Discrimination of

Glycoproteins P. J. Vickers, A. C. Pardos-Pardos, M. Quaglia, R. Jawad, D. L.

Fernandes, R. A. Gardener, D. I. R. Spencer, C. M. Radcliffe, L. Royle, P. M. Rudd, R.

A. Dwek, D. J. Harvey, A. Adams, A.S. McIntyre, C. Neususs, R. Brown. C. Jones.

Current Funding

Applicants

Project title

Funding agency

Applicants

PM Rudd et al

EuroCarb DB

EU

PM Rudd et al

338,584 €

Project title

Funding agency

GLYFDIS

EU

540K

Supervision of visitors

1. 1995 Dr. Kazuya Mori, Nippon Shinyaku Co. (Japan)

2. 1997 Dr. Mando Watson, St. Georges' Hospital, London

3. 1998 Philippe Van den Steen (University of Leuven)

4. 1998 Dr. Bergljot Magnadottir (University of Iceland, Reykjavík); RS grant

5. 1998 Dr. Lokesh Joshi (University of Cornell)

6. 1998 Ricardo Gutierrez Gallego (University of Utrecht); EU grant

7. 1998 Dr Regina Sattarova (University of Tashkent, Uzbequistan); RS grant

8. 1999 Dr. Olga Miroshnichenko (University of Kiev, Ukraine); RS grant

9. 1999 Steven Rodgers (Immunology Department, Haywards Heath Hospital)

10. 1999 Dr. Kim Sooyun (University of Korea)

11. 1999 Dr. Pru Bird - John Radcliffe Hospital

12. 2000 Mr. Mark Ritchie (Institute for Animal Health, Compton)

13. 2000 Dr. Bergljot Magnadottir (Unive rsity of Iceland, Reykjavík)

14. 2000 Beryl Moffat (MRC Unit, Dept. Biochemistry, Oxford

15. 2000 Nony Emmanuel (LFB, Paris)

16. 2000 Dr. Svetlana Astraucou (University of Grodno, Bellaruss) RS grant

17. 2000 Thuy Tran (University of Paris) Wellcome grant

18. 2000 Steven Rodgers (Immunology Department, Haywards Heath Hospital)

19. 2000 Dr. Lorella Navazio Dept. of Biology, University of Padova, Italy

20. 2000 Dr. Brett Garner: Wellcome Trust award (University of Wollongong, Australia)

21. 2000 Dr. Michael Butler (University of Manitoba) on sabbatical

22. 2001 Dr. Tian Dang (Xian Medical University): RS Royal Fellowship

23. 2001 Dr. Rosa Peracaula (Barcelona)

24. 2001 Dr. Irina Pimentiskya (Universityof Dniepropetrovsk, Ukraine)

25. 2001 Dr. Pablo Argibay (University of Buenos Aries, Argentina)

26. 2001 Manuela Miuzzo (University of Padua)

27. 2001 Monica Barclay (University of Manchester)

28. 2001 Britt Jorgensen (IMM)

29. 2002 Dr. Robert Boehm University of Bonn, Germany

13

30. 2002 Dr. Lone Omtvedt University of Oslo

31. 2002 Helen Bryant University of Bristol

32. 2002 Tracey Carter Brookes University, Oxford

33. 2002 Dr. Svetlana Astraucou (University of Grodno, Bellaruss) RS grant

34. 2002 Dr. Marjolein Robyn (University of Leiden)

35. 2002 Dr. Anja Roos (University of Leiden)

36. 2002 Dr. Y. Kimura (University of Okayama)

37. 2002 David Suter (University of Geneva)

38. 2002 Dr. Yoram Yedakh (Ben Gurion University, Israel)

39. 2003 Dr. Antonio Vallín García (Cuba)

40. 2003 Dawn Webber (University of Capetown)

41. 2003 Liz Matthews (University of Dublin)

42. 2004 Dr. Rosa Peracaula (University of Girona)

43. 2004 Dr. Sophie Richert (Serono Ltd)

44. 2004 Crina Paduara (University of Bucharest)

45. 2005 Dr. Yungon Kim (University of Seoul)

46. 2005 Dr. Jose Cremata (Biotech University, Cuba)

47. 2005 Dr. Sylvia Barrabes (University of Girona)

48. 2005 Claire

49. 2005 Sarah (Nottingham)

Co-supervisor (with Prof. R.A. Dwek) of students

Taj Mattu D.Phil

Peter Catellino M.Sc

Part 2 students

Gail Ritchie

Max Crispin

Manuela Miuzzo (Padova) Erasmus scheme

Chloe Tosevin

Gemma Tobiasen

Rachel Evans

Ben Sharpe

D.Phil. students

Su Yunpeng

David Shore

Chris Scanlan

Gail Ritchie

Max Crispin

Alison Critchley

Simon Fry

Maximilliano Jiminez (with Dr. Ian Wilson TSRI)

Huiping Ding (with Dr. Dennis Burton TSRI)

Karen Muindi (with Dr. M. Brenner, Harvard)

Crina Paduraru (with Dr. S. Petrescu, Bucharest and Dr. Peter Cresswell, Yale)

Stephanie Pollock (with Dr. Ian Wilson TSRI)

Jean Xu (with Dr. Dennis Burton TSRI)

Umi Hamid

Wellcome prize students:

Robin Schlinkert

Richard Hibbert

University Examining

1. 1998 - 2000 Oxford Biochemistry Department, Examiner Part 1

2. 1998 PhD Pauline Kemp (University of Canterbury, UK)

3. 1998 D.Phil. Transfer report Alpana Prasad (Dept. of Biochemistry, Oxford)

4. 2001 PhD Anna Hills (University of Canterbury)

5. 2001 PhD Philippe Van den Steen (University of Leuven)

6. 2001 PhD Fanning Zeng (University of Leeds)

7. 2002 DPhil transfer report Antu Dey

8. 2003 Oxford University examiner Biochemistry Part II

9. 2003 DPhil transfer report James Arnold

14

10. 2003 PhD Inge Nellison (University of Leuven)

11. 2004 DPhil transfer report Freddie Partridge

The Royal Society

Member of Panel of International Exchanges Committee covering the former Soviet Union

Public understanding of Science

Invited lectures:

1. 1990 General Studies Group: Headington School, Oxford

2. 1991 British Association of Young Scientists, Oxford

3. 1994 Sixth Form General Studies: St. Edward’s School, Oxford

4. 1994 Vale of the White Horse Deanery, Diocese of Oxford, Clergy Chapter

5. 1997 British Association of Young Scientists, Oxford

6. 1997/8 Centre for Theology and the Natural Sciences, University of Berkely,

California Participation in Three Workshops on Science and Religion:

7. 1997 Presentation: Science and Religion, CTNS, Berkeley, CA

8. 1998 Presentation: Science and Spirituality, CTNS, Berkeley, CA

9. 1998 Member of a Panel consisting of a Philoshopher, Psychologist, Theologian and Biochemist: Great Milton, Oxfordshire ’Knowing who you are’.

10. 1998 Theology Faculty, Postgraduate Seminar Oxford: Scientific method

11. 1998 Ian Ramsey Centre: respondent to lecture by Dr. J. Poulton Mitcohondrial

DNA: evolution and genetic counselling

12. 1998 Public conference Science and the Spiritual Quest, Berkeley, CA: Science and Spirituality

13. 1998 Advanced-level research conference for winners of the 1998 Templeton

Science and Religion course prize competition, Berkeley, CA.

14. 1998 Communi ty of St. Mary the Virgin, Wantage, Berks ‘Science and Spirituality’.

15. 1999 Undergraduate seminar on Biomedical ethics, Stanford University

16. 1999 Undergraduate seminar on Science and Religion, St. Mary’s College, Marago,

CA (Templeton Prize course, Prof. Ron Olowin)

17. 1999Undergraduate lecture, Caldwell College, Idaho (Templeton Prize course)

18. 1999 Public lecture, Caldwell College, Idaho (Templeton Prize course)

19. 1999 CTNS Public Forum, Berkeley

20. 1999 Theology Faculty, Oxford. Postgraduate Seminar (Templeton Prize course

21. 1999 Yeshiva University, New York (Templeton Prize course, Prof. Carl Feit)

22. 1999 Science and Religion course, Los Medanos College, CA (Templeton Prize course, Dr. Kate Boisvert)

23. 1999 Chautaqua Institution, New York State Opening lecture for 1999 season

24. 2000 Oxford University Sermon at St. Mary's: Religion and Science

25. 2000 Public Seminar at Western Oregon University Sc and Re course

26. 2000 Public Seminar at St Mary's College, Marago, CA Sc and Re course

27. 2000 University of San Francisco Public seminar Sc/Re course

28. 2000 Ian Ramsey Centre: respondent to lecture by Prof. Berj Bardakjian 'Cues of

Consciousness in Brain Cells

29. 2000 Venturfest: Talk on University spin off companies in ISIS section.

30. 2000 After Dinner Forum, State of the World Conference, New York

31. 2000 Seminar: Science, Intuition and Imagination, State of the World Conference,

New York

32. 2000 Seminar: Science, Altruism and Purpose, State of the World Conference,

New York

33. 2001 Co-chair SSQII Biological Sciences workshop, Universite Interdisciplinaire,

Paris

34. 2001 Theology Faculty Seminar, University of Oxford

35. 2001 New York: Public Conference at General Theological Seminary

36. 2001 Frontiers of Medicine: Human Genome-Human Being: London

37. 2001 Theology Faculty Seminar, University of Oxford

38. 2001 International symposium: Theology, Natural Sciences and Cultural Studies on

Resurrection Ruprecht-Karls-Universitat, Heidelberg

39. 2001 Introductory presentation in public conference with the Orthodox church on

Science and Religion, Bucharest, Romania

40. 2002 Ethics and Molecular Life Sciences in Technology, Medicine and Ecology, IC

London

41. 2002 Theology Faculty Ethics Seminar, University of Oxford

42. 2002 Universite Interdisciplinaire de Paris, Al Akhawayn University, Morocco

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43. 2002 Science and Spirit Summer Conference, Oxford

44. 2002 CS Lewis Seminar Series, Oxford

45. 2002 Chair Biology discussion section: SSQ conference, Granada, Spain

46. 2002 Fine tuning in the Universe St. George’s Windsor

47. 2002 Gakushuin University,Japan

48. 2002 Sermon at Mansfield College, Oxford

49. 2002 Ian Ramsey Centre, Oxford

50. 2003 M.Theol students, Oxford

51. 2004 University of Canterbury, Christchurch New approaches to anti-viral therapies

52. 2004 University of Canterbury, Christchurch Potential diagnostics for cancer

53. 2004 Bhaktivedanta Institute, Rome

54. 2005 Metanexus Institute, Philadelphia

55. 2005 Universitie Interdisciplinaire, Senlis, Paris

56. 2005 Bucharest and Constanza, Romania

57. 2006 Little Flower Seminary, Avula, India

58. 2006 Workshop on Creativity (Hirota) Kyoto

59. 2006 Meetings in ISSR Cambridge

60. 2006 GPSS meeting, Paris

Television

1. 2001 Central News (HIV)

2. 2001 Channel 4 News (Prions)

3. 2001 Channel 6 live (Prions)

4. 2001 French TV7 (Prions)

5. 2001 Romanian TV (Science and Religion)

6. 2002 Croatian TV (Glycosylation and immunity)

Radio

1. 1999 Chataqua local radio (Science and Religion)

2. 2001 Oxford radio (HIV b12 antibody; Science paper)

3. 2001 Fusion radio (HIV)

4. 2001 Fox FM (HIV)

5. 2001 Fusion radio (Prions D18 Fab, Nature paper)

6. 2001 Fox FM (Prions)

7. 2001 Sky radio News (Prions)

8. 2003 Oxford University students ’ radio

Prizes

2001 Templeton/ASA Prize for best video of a Science and Religion talk

PUS Publications:

1. Rapid Quantitative HPLC profiling of IgG glycans P.M. Rudd (1996) Oxford

GlycoSystems GlycoNews.

2. Release and enzymatic sequencing of human serum transferrin glycans Rudd, P.M.,

Iourin, O., Mattu, T.S., Guile, G.R. and Dwek, R.A. (1997) Oxford GlycoSystems

GlycoNews.

3. An automated strategy for carbohydrate sequencing OGS Technical bulletin 12

(1994) Resolution of glycoforms of RNase B by P/ACE Capillary Electrophoresis

PM. Rudd and E. Coghill Technical Information, Beckman (1993).

4. An automated strategy for carbohydrate sequencing P.M. Rudd OGS Technical

Bulletin 12 (1994).

5. Oligosaccharides in Biology P.M. Rudd Oxford Glycosystems GlycoNews Third (1993).

6. The Quest for God Rudd, P.M. (1989) Toc H Journal Point 3.

7. Science and the Spiritual Quest Rudd, P.M. (1997) CTNS Winter Bulletin 17 4 1-5.

8. The Science and Spiritual Quest Rudd, P.M. Science and Spirit Winter 1998-9 2-3.

9. Life the Universe and Everything - what is it for? Rudd, P.M. (2000) 189-191 God for the 21st century: Editor: Russell Stannard Templeton Press

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10. Mind the Light Rudd P.M. (2001) Metanexus web site.

11. Law, Chance and Opportunity in Nature: Insight into Natural and Human Creativity

Rudd P.M. (2001) Metanexus internet journal.

12. Science and the Spiritual Quest: New Essays by Leading

Scientists

Rudd, P.M. Editors Philip Clayton, et al., (London and New York:

Routledge, 2002).

13. Law, Chance and Opportunity Rudd, P.M. (2002) Proceedings

Romanian Academy.

14. Functional complexity in biology and religion (2005) Metanexus conference proceedings.

15. The proceedings of the Congress of October 2005, "Science and Orthodoxy, a Necessary

Dialogue", eds. Basarab Nicolescu and Magda Stavinschi, came out finally, besides two translations in Romanian: "When Science Meets Religion" by Ian Barbour and "Quarks,

Chaos and Christianity" by John Polkinghorne".

16. The Oxford Handbook of Religion and Science Eds Philip clayton and Zachary Simpson

OUP 2006 p 388-404

Membership of Boards and Learned Societies

Advisory Board of Ian Ramsay Centre, Oxford.

Elected member: International Society for Science and Religion

Global perpectives in Science and Spirituality: Judging panel for funding 2004, 2006

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