Chemistry 226 - Nicholls State University

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Chemistry 226 – 5T
Organic Chemistry Laboratory I
Spring 2010
Instructor: Dr. Jeremy Wessel
Office: Pel 245C
Office Phone: (985) 448-4504
E-mail: [email protected]
Office Hours: 10:00-12:00 MWF, 1:00-2:00 MW, 10:30-11:30 TR
Catalog Description: CHEM 226. Organic Chemistry Laboratory. 2-0-6. Prerequisite: CHEM
110. Prerequisite or co-requisite: CHEM 222. An introduction to the study of the properties and
preparation of organic compounds.
Prerequisite: CHEM 110
Prerequisite or corequisite: CHEM 222
Required Texts and Other Materials:
1 – The Organic Chem Lab Survival Manual, A Student's Guide to Techniques, 8th
Edition by Zubrick
2 - Safety goggles
3 - Laboratory notebook. Bound, duplicating with tear out sheets
Required Supplemental Readings: Experimental procedures will be posted on Blackboard.
Student Outcome Goals and Objectives:
At the end of this course the student will be able to
 Learn the 12 principles of green chemistry
 Compare and contrast green chemical routes with older methods
 Use melting point/mixed melting point to characterize compounds
 Extract products from various solvents,
 Recrystallize products,
 Perform fractional and simple distillation,
 Synthesize various organic compounds,
 Analyze and identify organic compounds by infrared spectroscopy, thin-layer
chromatography, gas chromatography, and nuclear magnetic resonance.
Schedule of Experiments
(Reading assignments from Zubrick in parentheses.)
Day
Experiment
26 January
Solventless Aldol (ch. 1-4,
7, 9, 11, 13; pp. 88-93)
Greener Bromination of EStilbene (pp. 146, 201-2)
2 February
9 February
16 February
NMR (ch. 33) and GC (ch.
30)
Mardi Gras Holiday
Day
21 January
28 January
Experiment
Check In/Safety
4 February
Start Ethanol from
Molasses
Distillation of Ethanol
from Molasses (ch. 19, 29,
34)
11 February
NMR and GC
18 February
Dehydration (ch. 10) and
IR (ch. 32)
23 February
2 March
9 March
16 March
23 March
30 March
6 April
13 April
20 April
27 April
4 May
Synthesis and
Recrystallization of Adipic
Acid
Start Solid Phase
Photochemistry
25 February
Synthesis and
Recrystallization of Adipic
Acid*
4 March
Review
Midterm
11 March
18 March
Liquid CO2 Extraction
Oxidative Coupling of
Alkynes: Glaser-EglintonHay Coupling
Friedel-Crafts Reaction:
Acetylation of Ferrocene*
Oxidative Coupling of
Alkynes: Glaser-EglintonHay Coupling (ch. 21, 27)
Friedel-Crafts Reaction:
Acetylation of Ferrocene
Electrophilic Aromatic
Iodination
Spring Vacation
Biodiesel
Microwave Synthesis of
5,10,15,20Tetraphenylporphyrin
Combinatorial Chemistry2
25 March
1 April
8 April
15 April
22 April
29 April
Finish Solid Phase
Photochemistry
Spring Vacation
Microwave Synthesis of
5,10,15,20Tetraphenylporphyrin (ch.
28)
Nucleophilic Substitution
of Fabric Dyes1
Review
Final
Course Content: 1freshly washed 100% cotton material or T-shirt required by each student
2
samples require 24 hours incubation so each student will be required to return the next day
(not class day) to view the plates
Method of Evaluation:
All students will perform experiments using proper safety practices.
Notebook: 25 points/experiment
14 experiments
350 points
*Formal reports on adipic acid, acetylferrocene (50 pts. each) 100 pts
Midterm Exam
100 points
Final Exam
100 points
650 points
Grades will be determined using the following scale:
A: 90-100
B: 80-90
C: 70-80
D: 60-70
F: <60
Academic Dishonesty Policy: Any student found cheating will be subject to the penalties stated in
Student Code of Conduct; including, but not limited to, a score of zero on exam, expulsion from
the class, or expulsion from the University.
Attendance Policy: Attendance is mandatory.
Make-up Policy: Missed labs can be made up for an excused absence. Make-ups must be
completed within two weeks of the experiment date.
Academic Disabilities Policy: If you have a documented disability that requires assistance, you
will need to register with the Office of Disability Services for coordination of your academic
accommodations. The Office of Disability Services is located in Peltier Hall, Room 100-A. The
phone number is (985) 448-4430 (TDD 449-7002).
Academic Grievances:
The proper procedure for filing grade appeals or grievances related to academic matters is listed
in Section 5 of the Code of Student Conduct and at the following link:
http://www.nicholls.edu/documents/student_life/code_of_conduct.pdf.
Continued Learning following an Extreme Emergency
The following guidelines are meant: to help the business of education continue at Nicholls State
University in the aftermath of an extreme emergency situation; to help faculty and students
understand their roles in completing education requirements for courses in progress when the
emergency began; and to encourage faculty to be imaginative and resourceful in finding ways to
continue the education of students and the work of the university.
Faculty responsibilities:
• Faculty members are responsible for their development in the use of the Blackboard (or
designated) software.
• Faculty members are responsible for having a plan for continuing their courses using only
Blackboard and email.
• Faculty members should be allowed to continue their course in whatever way suits the
completion of the course best, and encouraged to be creative in the continuation of these courses.
• Any adjustments or compensations made to a student’s progress in special programs with labs,
clinical sequences (i.e. Culinary, Nursing, etc.), or the like should be made only in the immediate
semester following the emergency.
 Faculty members are responsible for including these guidelines in all syllabi.
Student responsibilities:
• Students are responsible for reading regular emergency notifications on the NSU website.
• Students are responsible for knowing how to use and access Blackboard.
• Students are responsible for being familiar with emergency guidelines.
• Students are responsible for evacuating textbooks and other course materials.
• Students are responsible for knowing their Blackboard login and password
• Students are responsible for contacting faculty regarding their intentions for completing the
course.
NOTE: Faculty and students should be open, flexible, and show compassion in determining the
precise course of action.
Semester Withdrawals: The last day to withdraw from the class with a ‘W’ is March 31, 2010.
Class Disruptions: The use of cellular phones, pagers or any other electronic personal device is
prohibited in class. Any infractions will result in dismissal from class and 0 for the experiment.
DISCLAIMER. This syllabus is not a contract and no part of it should be construed as
such. The syllabus is subject to change. Students will be notified of these changes in a
timely manner.
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