Course Syllabus STS 6674 Ethical Considerations of Science, Technology and Policy Summer 2003 Tuesdays, 6:30-9:15pm Instructor: Mark S. Frankel, Ph.D. Phone: 202.326.6793 Fax: 202.289.4950 Email: mfrankel@aaas.org Office: 1200 New York Ave., NW, Washington, DC 20005 Office Hours: By appointment. Contact me by phone or email to arrange an appointment, as needed. Course Description This course will focus on the ethical dimensions of science and technology in the context of policy making. Ethics is essentially about doing the “right thing.” Simple in principle, but much more complicated in the policy environment, where so much can be at stake. On the one hand, people may not know what the “right thing” to do is in a complex situation, and will look to whatever guidelines and policies exist to help them. On the other hand, people know precisely the “right thing” to do, but fail to follow through because of external influences (e.g., political pressure, promise of financial gain, the rush to publish first). The course will examine both situations by focusing on specific policy debates, some of which have been highly visible during the past few years. The course will begin with an introduction to ethical analysis. Students will be introduced to various ethical theories and concepts that have been used to interpret and assess both individual and institutional behavior. Students will be expected to apply this knowledge to the specific policy debates covered in the course. For each policy debate examined, students should seek to answer the following questions: What are the values at stake and the ethical issues in the particular debate? How were they handled by key participants in the debates? To what extent did ethical considerations shape the outcomes/policy? What is your assessment of how the ethical issues were resolved/unresolved? What outcome(s) would you have preferred and why? These will be the core questions that will frame our class discussions and that should frame your out-of-class assignments as well. We will apply those questions (and others) to the policy debates surrounding: research misconduct, stem cell research, human subjects research in the social and behavioral sciences, the increasing connection between science and commerce, how the events of 9/11 and broader national security concerns affect the conduct, use, and dissemination of science, the uses and abuses of anonymity in the context of information technologies, and how science is used by the courts and the ethics associated with scientists and engineers serving as an expert witness. Course Requirements The course consists of readings, lectures, in-class student presentations, and writing assignments. A list of required readings for each class session appears below. I will introduce the topic for each session. After that, students will be asked to make short presentations (15-20 minutes). There may be more than one student presentation for each session. A form for listing your session preferences will be handed out at the first class and due the following week. Prior to each session, I will distribute a list of questions that will help focus the student presentations, but students are encouraged to expand the list. Students presenting are expected to consult source materials beyond the required readings. During the course, I will distribute “case scenarios” related to some of the topics covered. I anticipate 3-4 such cases during the term. The week after distribution, students will be expected to hand in a 3-5 page (double spaced) analysis of the case, and we will begin the class with a brief discussion of that case. Final Exam Paper: The assignment is to prepare a paper on a scientific advance or technology not covered in the course and to map out its social implications, identify the specific ethical issues it raises, and recommend policy for its (non) development and use. On August 5, students will present their papers for class discussion and my critique. Students will then revise their papers and submit a final version to me by August 8. What will be key to my evaluation of this paper is how well your analysis and documentation support your recommendations. The paper should be no more than 12 double-spaced pages plus references. Grading 50% Class participation. Students will receive a grade for their assigned presentations; all students will be graded on their general participation. 25% Written analyses of the case scenarios 25% Final exam paper Session Topics and Required Readings (Readings are subject to change.) May 20 Introductions and Course Overview May 27 Ethical Theory and Concepts Excerpts from Peter Y. Windt, et al., Ethical Issues in the Professions (NJ: Prentice Hall, 1989), pp. 9-16, pp. 527-534 (handout) William Gellermann, Mark S. Frankel, & Robert F. Ladenson, Values and Ethics in Organization and Human Systems Development: Responding To Dilemmas in Professional Life (CA: Jossey-Bass Publishers, 1990), pp. 61-108 (handout) Larry R. Churchill, Rationing Health Care in America: Perceptions and Principles of Justice (Indiana: University of Notre Dame Press, 1987), pp.43-69 (handout) June 3 Scientific Misconduct & Research Integrity National Academy of Sciences, Responsible Science: Ensuring the Integrity of the Research Process, Vol. I (Washington, DC: National Academy Press, 1992), pp. 36-46 (handout) Frederick Grinell, The Scientific Attitude, 2nd Edition (N.Y.: The Guilford Press, 1992), pp.153-57 (handout) Albert H. Teich & Mark S. Frankel, Good Science and Responsible Scientists (Washington, DC: AAAS, March 1992); (handout) Howard Schachman, “What is Misconduct in Science?” Science, vol. 261:148-49, July 9,1993 (handout) Nicholas H. Steneck, “Assessing the Integrity of Publicly Funded Research,” Proceedings of the First ORI Research Conference on Research Integrity, November 2000; http://ori.hhs.gov/multimedia/acrobat/papers/steneck.pdf Federal Policy on Research Misconduct; http://www.ostp.gov/html/001207_3.html Bruce Alberts and Kenneth Shine, “Scientists and the Integrity of Research,” Science, vol. 266: 1660-1661, December 9, 1994 (handout) PHS Policy on Instruction in the Responsible Conduct of Research (RCR)—Suspended; http://ori.dhhs.gov/html/programs/finalpolicy.asp Institute of Medicine, Integrity in Scientific Research (2002), Executive Summary (handout) June 10 Stem Cell Research Audrey R. Chapman, Mark S. Frankel, & Michele S. Garfinkel, Stem Cell Research and Its Applications (Washington, DC: AAAS, November 1999); http://www.aaas.org/spp/dspp/sfrl/projects/stem/main.htm National Bioethics Advisory Commission, Ethical Issues in Human Stem Cell Research (1999), Executive Summary; http://www.georgetown.edu/research/nrcbl/nbac/execsumm.pdf National Institutes of Health Policy on Stem Cell Research (2001); http://www.nih.gov/news/stemcell/082701list.htm Institute of Medicine, Stem Cells and the Future of Regenerative Medicine, Executive Summary, 2002; http://books.nap.edu/html/stem_cells/report.pdf President’s Council on Bioethics, Human Cloning and Human Dignity: An Ethical Inquiry (2002), Executive Summary; http://www.bioethics.gov/cloningreport/execsummary.html U.S. Department of Justice position on human cloning, May 15, 2002 (handout) California Senate Bill No. 253, Stem Cells, Human Tissue, Research (2002) (handout) George J. Annas, “Cloning and the U.S. Congress,” New England Journal of Medicine 346: 1599-1602, May 16, 2002 (handout) Janet D. Rowley, et al., “Harmful Moratorium on Stem Cell Research,” Science 297: 1957, September 20, 2002 (handout) June 17 Human Subjects Research The Belmont Report (1978); http://ohrp.osophs.dhhs.gov/humansubjects/guidance/belmont.htm Common Rule; http://ohrp.osophs.dhhs.gov/humansubjects/guidance/45cfr46.htm American Association of University Professors, “Protecting Human Beings: Institutional Review Boards and Social Science Research” 2001; http://www.aaup.org/statements/Redbook/repirb.htm C.K. Gunsalus, “Rethinking Protections for Human Subjects,” The Chronicle of Higher Education, November 15, 2002 (handout) NHRPAC Social & Behavioral Science Working Group, “Draft Recommendations Regarding Risk and Harm”; http://www.asanet.org/public/humanresearch/riskharm.html Mark S. Frankel & Sanyin Siang, Ethical and Legal Aspects of Human Subjects Research on the Internet, November 1999; http://www.aaas.org/spp/sfrl/projects/intres/report.pdf June 24 Science & Commerce I Michael S. Pritchard, “Conflicts of Interest: Conceptual and Normative Issues,” Academic Medicine, vol. 71:1305-1313, December 1996 (handout) Mark S. Frankel, “Perception, Reality, and the Political Context of Conflict of Interest in University-Industry Relationships,” Academic Medicine, vol. 71: 1297-1304, December 1996 (handout) Eyal Press and Jennifer Washburn, “The Kept University,” The Atlantic Monthly, March 2000; http://www.theatlantic.com/issues/2000/03/press.htm Kenneth J. Rothman, “Conflict of Interest: The New McCarthyism in Science,” The Journal of the American Medical Association, vol. 269: 2782-2784, June 2, 1993 (handout) July 1 Science & Commerce II Public Health Service, “Objectivity in Science,” (1995); http://grants1.nih.gov/grants/guide/notice-files/not95-179.html Association of American Universities, Report on Individual and Institutional Financial Conflict of Interest (October 2001); http://www.aau.edu/research/COI.01.pdf Association of American Medical Colleges, Protecting Subjects, Preserving Trust, Promoting Progress (December 2001); http://www.aamc.org/members/coitf/firstreport.pdf Association of American Medical Colleges, Protecting Subjects, Preserving Trust, Promoting Progress II (October 2002); http://www.aamc.org/members/coitf/2002coireport.pdf July 8 Science and National Security I Harold C. Relyea (ed.), Striking a Balance: National Security and Scientific Freedom, First Discussions (Washington, DC: American Association for the Advancement of Science, May 1985), pp. 1-5, 29-46, 51-55, 68-74 (handout) “On Balancing Openness and Secrecy At U.S. Weapons Laboratories,” U.S. National Academies, November 19, 1999 (handout) Committee on Science & Technology for Countering Terrorism, Making the Nation Safer: The Role of Science and Technology in Countering Terrorism (Washington, DC: National Academies Press, 2002), pp. 25-38 (handout) “On Scientific Openness and National Security,” U.S. National Academies, May 21, 1999 (handout) “The Universality of Science and Freedom in the Conduct of Research,” AAAS Board of Directors, June 25, 1999; http://www.aaas.org/spp/scifree/resolution.shtml “Current Visa Restrictions Interfere with U.S. Science and Engineering Contributions to Important National Needs,” U.S. National Academies, December 13, 2002 (handout) July 15 Science and National Security II Faith McLellan, “Academic Freedom or Speaking with the Enemy,” The Lancet, 360: 731, September 7, 2002 (handout) H. Res. 514, U.S. House of Representatives, July 26, 2002; http://www.fas.org/sgp/congress/2002/hres514.html Raymond A. Zilinskas & Jonathan B. Tucker, “Limiting the Contribution of the Open Scientific Literature to the Biological Weapons Threat,” Journal of Homeland Security, December 2002; http://www.homelandsecurity.org/journal/Articles/tucker.html “Statement on Scientific Publication and Security,” February 2003; http://www.sciencemag.org/cgi/reprint/299/5610/1149 Statement from Bruce Alberts, Wm. A. Wulf, and Kenneth I. Shine, U.S. National Academies, October 29, 2001 (handout) The White House, National Security Decision Directive 189, “National Policy on the Transfer of Scientific, Technical and Engineering Information,” September 21, 1985 (handout) Mitchel B. Wallerstein, “Science in an Age of Terrorism,” Science, 297: 2169, September 27, 2002; http://www.sciencemag.org/cgi/reprint/297/5590/2169.pdf William Matthews, “OMB Weighs Info Classification,” FCWCOM, September 16, 2002; http://www.fcw.com/fcw/articles/2002/0916/newsomb-09-16-02.asp “Science and Security in an Age of Terrorism,” U.S. National Academies, October 18, 2002 (handout) July 22 Information Technology John C. Dvorak, “Pros and Cons of Anonymity,” PC Magazine, December 30, 2002; http://www.pcmag.com/print_article/0,3048,a=35187,00.asp Helen Nissenbaum, “The Meaning of Anonymity in an Information Age,” The Information Society, 15: 141-144, April-June 1999 (handout) John Markoff, “Pentagon Plans a Computer System that Would Peak at Personal Data of Americans,” The New York Times, November 9, 2002 (handout) John Markoff, “Agency Weighed, but Discarded, Plan Reconfiguring the Internet,” The New York Times, November 22, 2002 (handout) “AOL loses Internet Privacy Ruling,” Reuters/MSNBC News, November 4, 2002 (handout) Rob Kling, et al., “Assessing Anonymous Communications on the Internet: Policy Deliberations,” The Information Society, 14: 79-90, April-June 1999; http://www.slis.Indiana.edu/TIS/readers/full-text/152%20kling.pdf July 29 Science in the Legal System Stephen G. Breyer, “The Interdependence of Science and Law,” 1998; http://www.aaas.org/meetings/1998/breyer98.htm Margaret A. Berger, “Expert Testimony: The Supreme Court’s Rules,” Issues in Science and Technology, Summer 2000; http://www.nap.edu/issues/16.4/berger.htm John Hardwig,” Toward an Ethics of Expertise,” in Daniel E. Wuesta (ed.), Professional Ethics and Social Responsibility (Lanham, MD: Rowman & Littlefield Publishers, Inc., 1994), pp.83-101 (handout) William W. Schwarzer, “Ethics and the Expert Witness,” Shepard’s Expert and Scientific Evidence, vol. 2 (3): 587-592, Winter 1995 (handout) Mark S. Frankel, “Ethics and the Forensic Sciences: Professional Autonomy in the Criminal Justice System,” Journal of Forensic Sciences, vol. 34 (3): 763-771, May 1989 (handout) Anthony Champagne, et al., “Are Court-Appointed Experts the Solution to the Problems of Expert Testimony?” Judicature, vol. 84 (4): 178-183, January-February 2001(handout) Ned Miltenberg, “Myths About ‘Neutral’ Scientific Experts,” TRIAL, January 2000 (handout) August 5 Presentation and Discussion of Final Exam Papers