Skin Deep January/February 2013 An Advanced Tissue newsletter written by Carolyn Brown BS, MEd, RN, ARM, CWS, FACCWS Ask Carolyn: Q: I am a new treatment nurse in Utah and have a question. Our Medical Director is ordering Silvadene Cream for all chronic wounds. Would you describe this product and summarize any precautions. A Silvadene A: Sil d Cream C is i a topical t i l antimicrobial ti i bi l drug d used d ffor the th prevention ti and d treatment of wound infection in patients with second- and third-degree burns. Before using Silvadene, obtain a medical history specifically including: •Allergy to silver sulfadiazine or another sulfa antibiotic (such as sulfamethoxazole) •Kidney or liver problems or low WBC Various products may interact with Silvadene, including: •Cimetidine (Tagamet) •Phenytoin (Dilantin),skin products containing sodium sulfacetamide •Enzymes used to remove dead tissue such as collagenase (Santyl) Have a question for Carolyn? E-mail mhendrix@advtis.com . What is the difference between Slough and Eschar isn’t it all dead tissue? Injury or lack of blood flow to the skin results in necrotic or dead tissue. As the tissue dies, it changes color and consistency and adheres to the wound bed. bed Necrotic tissue is called either slough or eschar. Slough is hydrated (moist) necrotic tissue. The color of slough varies, including: yellow, gray, tan and brown. Slough is soft and thin, fibrinous or stringy. Eschar is dryy ((no moisture)) necrotic tissue;; it has a firm, dry, leather, black-to-brown appearance. As eschar is moistened, it slowly turns to slough. The presence of slough or eschar indicates full thickness tissue damage and effective treatment requires debridement. Possible Alternative for Silvadene Cream An alternative treatment for wounds not caused by a burn is SilvaSorb Gel. A detailed study comparing Silvadene Cream and SilvaSorb Gel can be found on the Advanced Tissue website for your review. www.advtis.com Weight Loss: Indicator for delayed healing Adequate nourishment is critical to healthy skin and wound healing. Literature suggests that weight loss is a significant predictor of pressure ulcer development and a strong indicator of delayed healing. The dietician should be consulted regarding significant weight loss as a prevention intervention. intervention Variations in Normal Healing The events associated with wound healing do not always proceed smoothly. Two deviations in healing may occur even with optimal care: Exuberant granulation, or proud flesh,, results from the formation of excessive ggranulation tissue that may protrude above the margins of the wound. Keloids are large, bulging, scars caused by abnormal amounts of collagen present in the connective tissue. Consult the physician for treatment orders. For more information about Advanced Tissue, please call 866‐217‐9900 or go to advtis.com We recommend you copy our newsletter and post for your clinicians to read. After all clinicians have initialed--file in an education binder. During survey, this binder will document multiple educational opportunities you have provided.