Product Data Sheet
Product Name:
Misoprostol
CAS No.:
59122-46-2
Cat. No.:
HY-B0610
MWt:
382.53
Formula:
C22H38O5
Purity :
>98%
DMSO
y
Solubility:
Mechanisms:
Pathways:GPCR/G protein; Target:Prostaglandin Receptor
Biological Activity:
Misoprostol(SC29333) is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric
ulcers, to treat missed miscarriage, to induce labor, and to induce abortion.
Target: Prostaglandin Receptor
Misoprostol is a synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of
gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective antiulcer agent and also has oxytocic properties. Misoprostol seems to inhibit gastric acid secretion by a
direct action on the parietal cells through binding to the prostaglandin receptor. Administration of
misoprostol to EP3+/+ and EP3-/- mice showed similar levels of infarct rescue, indicating that
misoprostol
p
p
protection was not mediated through
g the EP3 receptor.
p
Taken together,
g
, these findings
g
suggest a novel function for misoprostol as a protective agent in cereb...
References:
[1]. Li, J., et al., Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against
cerebral ischemia. Neurosci Lett, 2008. 438(2): p. 210-5.
[2]. http://www.drugbank.ca/drugs/DB00929
Caution: Not fully tested. For research purposes only
Medchemexpress LLC
www.medchemexpress.com
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