Couse Code & Title : CM1051 Basic Biology and Biochemistry Academic Units : 3 AU Pre-requisite : H2 Level Chemistry or equivalent Course Description : CM1051 Basic Biology and Biochemistry [Online interactive digital media (IDM)-based courseware with self-assessments: 3040 hours depending on the background and proficiency of students; Tutorial with team-based learning elements: 18 hours] Course Outline IDM-based online courseware structured into Learning Objects (LOs) will be posted on NTULearn according to the schedule shown. This will be followed by 2 h tutorials on 9 of the weeks as shown below. Week 1 LO 1 2 2 3 3 4 5 6 7 8 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Module : Content Introduction 1: Orientation to the “study of life” Introduction 2: Basics from chemistry: elements of matter, water and buffer Introduction 3: Origins of life & biological diversity (include virus) Introduction 4: The human body Macromolecules 1: Introduction Macromolecules 2: Carbohydrates Macromolecules 3: Nucleic Acids Macromolecules 4: Proteins Macromolecules 5: Lipids Cells 1: The basic unit of life (Introduction) Cells 2: Prokaryotes Cells 3: Eukaryotes Genetic basis of life 1: Introduction Genetic basis of life 2: The central dogma Genetic basis of life 2: Regulation of gene expression Genetic basis of life 4: Diversity within Population Continuity of Life 1: DNA replication Continuity of Life 2: Cell division - Prokaryotes Continuity of Life 3: Cell division - Eukaryotes (cell cycle, mitosis, meiosis) Continuity of Life 4: Concepts of asexual and sexual reproduction Tutorial (2h) Yes Yes Yes Yes Yes Yes 21 9 10 11 12 22 23 24 25 26 27 28 29 30 31 32 Continuity of Life 5: Reproduction at the macroorganism level Mutation 1: Mendelian genetics vs Molecular Yes genetics Mutation 2: Evolution Mutation 3: Molecular biotechnology Metabolism 1: Bioenergetics Metabolism 2: Digestive system (extracellular metabolism) Metabolism 3: Cellular metabolism Yes Metabolism 4: Cellular respiration Metabolism 5: Metabolic integration Perspectives 1: The era of “-Omics” Yes Perspectives 2: Personalization of healthcare Perspectives 3: Beyond the discipline of Biology Learning Outcomes 1. 2. 3. 4. To understand the basics of biology at the “molecular level” To appreciate the link of the molecular level to the macrobiology level To appreciate the unifying theme of living things To gain an awareness of the link of biology with other disciplines Student Assessment Students will be assessed by: a. Final 2.5-hour written examination (60%) b. Continual Assessment comprising of: - Mid-semester quiz (30%) - Presentation (10%) Written Examination: The final examination will consist of multiple choice questions with one correct (best) answer and multiple choice questions with more than one correct answers (and students are required to choose all correct answers to be awarded any marks). Mid-semester Quiz: The quiz will consist of questions requiring short response answers. Presentation: Each student will be rostered to present the team’s conclusion to the class at the end of tutorial sessions. These will be graded on an individual basis. Textbooks/References Johonson et al, Essentials of the Living World (4th Edition), McGraw-Hill, International Edition, 2012 Mader et al, Biology (11th Edition), McGraw-Hill International Edition, 2013 Biochemistry: The Molecular Basis of Life, by Trudy Mckee & James R. Mckee, 5th, McGraw-Hill, 2013