CURRICULUM VITAE NAME Alison DeLong TITLE Assistant

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DeLong CV-- 1
CURRICULUM VITAE
NAME
Alison DeLong
TITLE
Assistant Professor of Biology
Brown University
ADDRESS
Department of Molecular Biology, Cell Biology and Biochemistry
Box G-J119
phone: 401-863-3888
Brown University
FAX: 401-863-2421
Providence, RI 02912
email: [email protected]
EDUCATION
1989 Ph.D., Microbiology and Molecular Genetics, Harvard University, Cambridge MA
1982 B.A. with Honors, English Literature, Swarthmore College, Swarthmore, PA
POSITIONS
2002 - present Assistant Professor, Department of Molecular Biology Cell Biology and
Biochemistry, Brown University
1996 - 2002 Assistant Professor (Research), Department of Molecular Biology Cell Biology
and Biochemistry, Brown University
1994 - 1995 Associate Research Scientist with Prof. Dieter Söll, Department of Molecular
Biophysics and Biochemistry, Yale University
1992 - 1994 Postdoctoral Fellow with Prof. Dieter Söll, Department of Molecular
Biophysics and Biochemistry, Yale University
1989 - 1992 Postdoctoral Fellow with Prof. Stephen Dellaporta, Biology Department, Yale
University
HONORS
1989-1992 National Science Foundation Postdoctoral Fellowship
1982-1985 National Science Foundation Graduate Fellowship
1982 Phi Beta Kappa
DeLong CV-- 2
MEMBERSHIPS
Genetics Society of America
American Society of Plant Biologists
GRANTS
Current
Regulation of Protein Phosphatase 2A Activity in Arabidopsis by the RCN1 Protein, (NSF
IOB-0446039) 2/1/05 - 1/31/08. PI
Past
Regulation of Protein Phosphatase 2A Activity in Arabidopsis by the RCN1 Protein, (NSF
IBN-0135458) 2/1/02 - 1/31/05
Center for Genetics and Genomics (NIH/NCRR 1 P20 RR15578-01; John Sedivy, P.I.)
10/01/00-9/30/05. This award funded several interdisciplinary projects and core
facilities in a Center of Biomedical Research Excellence (COBRE). Dr. Sedivy was
the Director of the Center.
Functions of Protein Phosphatase 2A Isoforms in Arabidopsis Development (NSF IBN9986017) 3/1/00 - 2/29/04
Function of Protein Phosphatase 2A in Control of Proliferation: Isolation and Analysis of
Dominant-Defective Mutants (U.S. Army Breast Cancer Research Program
BC962351) 5/15/97 - 6/14/00
Functions of Protein Phosphatase 2A Isoforms in Arabidopsis Development (NSF IBN9604782) 2/1/97 - 1/31/00
Molecular Genetics of Gravitropism in Arabidopsis (Co-PI with Dieter Söll, Yale
University; NSF IBN-9416027) funded by the NASA/NSF Joint Program in Plant
Biology 9/1/94 - 8/31/99
PUBLICATIONS
DeLong A. (2006) Switching the flip: protein phosphatase roles in signaling
pathways. Invited review for Current Opinion in Plant Biology 9:470477.
Muday, G.K., S. Brady, C. Argueso, J. Deruère, J. Kieber and A. DeLong (2006) RCN1regulated phosphatase activity and EIN2 modulate hypocotyl gravitropism by a
mechanism that does not require ethylene signaling. Plant Physiology 141:16171629.
DeLong CV-- 3
Zhou, H.W., C. Nussbaumer, Y. Chao and A DeLong (2004) Disparate roles for the
regulatory A subunit isoforms in Arabidopsis protein phosphatase 2A. The Plant
Cell 16:709-722.
Kwak, J.M., J.-H. Moon, Y. Murata, K. Kuchitsu, N. Leonhardt, A. DeLong, and Schroeder,
J.I. (2002 ) Disruption of a guard cell-expressed protein phosphatase 2A regulatory
subunit, RCN1, confers abscisic acid insensitivity in Arabidopsis. The Plant Cell
14:2849-2861.
DeLong, A., K. Mockaitis and S. Christensen (2002) Protein phosphorylation in the
delivery of and response to auxin signals. Plant Mol Biol. 49:285-303.
Muday, G.K. and A. DeLong (2001) Polar auxin transport: Controlling where and how
much. Trends in Plant Science 6:535-542.
Rashotte, A. M., A. DeLong and G. K. Muday (2001) Genetic and chemical reductions in
protein phosphatase activity alter auxin transport, gravity response and lateral root
growth. The Plant Cell. 13:1683-1697.
Willows R. D., S. M. Mayer, M. S. Foulk, A. DeLong, K. Hanson, J. Chory, and S. I. Beale
(2000) Phytobilin biosynthesis: the Synechocystis sp. PCC 6803 heme oxygenaseencoding ho1 gene complements a phytochrome-deficient Arabidopsis thaliana hy1
mutant. Plant Mol Biol. 43:113-20.
Lizotte, D., D. D. McManus, H. R. Cohen, and A. DeLong (1999) Functional expression of
human and Arabidopsis protein phosphatase 2A in Saccharomyces cerevisiae and
isolation of dominant-defective mutants. Gene 234:35-44.
Deruère, J., K. Jackson, C. Garbers, D. Söll and A. DeLong (1999) The RCN1-encoded A
subunit of protein phosphatase 2A increases phosphatase activity in vivo. The Plant
Journal 20: 389-399.
Garbers, C., A. DeLong, J. Deruère, P. Bernasconi and D. Söll (1996) A mutation in Protein
Phosphatase 2A Regulatory Subunit A Affects Auxin Transport in Arabidopsis.
EMBO J. 15: 2115-2124.
DeLong, A., A. Calderon-Urrea, and S. Dellaporta (1993) Sex Determination Gene
TASSELSEED2 of Maize Encodes a Short-Chain Alcohol Dehydrogenase Required
for Stage-Specific Floral Organ Abortion. Cell 74: 757-768.
Dellaporta, S., M. Moreno and A. DeLong (1991) Cell lineage analysis of the gynoecium
of maize using the transposable element Ac. Development Supplement 1: 141-147.
DeLong, A. and M. Syvanen (1991) Trans-acting transposase mutant from Tn5. Proc. Natl.
Acad Sci. USA 88: 6072-6076.
DeLong CV-- 4
DeLong, A. and M. Syvanen (1990) Membrane Association of the Tnp and Inh Proteins of
IS50R. J. Bacteriol. 172: 5516-5519.
Ward, D. F., A. DeLong and M. E. Gottesman (1983) E. coli nusB Mutations that Suppress
nusA1 Exhibit λ N Specificity. J. Mol. Biol. 168: 73-85.
Lizotte, D., Blakeslee, J.J., Siryaporn A., Heath, J. and A. DeLong A PP2A active site
mutant impedes growth and causes misregulation of native catalytic subunit
expression. In revision.
INVITED LECTURES
The Missouri Symposium: Plant Protein Phosphorylation and Dephosphorylation,
Columbia, Missouri, 5/22 - 5/25/07
Universität für Bodenkultur Wien (Institute of Applied Genetics and Cell Biology) 3/23/07
Tel Aviv University (Plant Science Program) 3/21/07
Hebrew University Jerusalem (Plant Science Program) 3/19/07
Wake Forest University (Biology Department) 1/31/07
Purdue University (Horticulture Department) 12/2/04
Indiana University-Purdue University Indianapolis (Biology Department) 4/30/04
The Missouri Symposium: Plant Protein Phosphorylation and Dephosphorylation,
Columbia, Missouri, May 28 - 31, 2003
University of New Hampshire (Genetics Program) 5/7/01
EMBO Workshop on Auxin Biology, Calcatoggio, Corsica, France, May 13 - 18, 2000
The Missouri Symposium: Plant Protein Phosphorylation and Dephosphorylation,
Columbia, Missouri, 4/12 - 4/15/00
McGill University (Biology Department) 11/9/98
University of Massachusetts/Amherst (Plant Biology Graduate Program) 11/13/97
DeLong CV-- 5
PROFESSIONAL SERVICE
Panel member, NSF Integrative Plant Biology grant program 2001, 2003, 2005
Panel member, USDA National Research Initiative Competitive Grants Program (Plant
Growth and Development) 2000, 2002
Ad hoc grant reviewer for National Science Foundation (Integrative Plant Biology Program)
1996, 2000, 2002, 2004, 2005, 2006; (Plant Genome Initiative) 1998, 2004; (Signal
Transduction and Regulation) 1999; USDA National Research Initiative Competitive
Grants Program (Plant Genetic Mechanisms, Plant Growth and Development) 1996,
1997, 2001, 2003, 2006.
Manuscript reviews for Proceedings of the National Academy of Sciences U.S.A. (2005),
FEBS Letters (2005), Trends in Plant Science (2005, 2007), Plant Physiology (1997,
2000, 2001, 2003, 2007) The Plant Journal (2000, 2001), Genetics (2000), Plant
Science (2001), Journal of Biological Chemistry (2002), The Plant Cell (2002, 2003,
2007) Plant Molecular Biology (2007).
Editorial adviser, Biochemical Journal, July 1 2003 - present.
Discussion leader, Gordon Conference on Mechanotransduction and Gravity Signaling in
Biological Systems, July 20 -25, 2003
Participation in production of an educational video “Roots of Discovery” as part of
NASA/NASF Network for Research on Plant Sensory Systems
MEETINGS ATTENDED
Plant Protein Phosphorylation Workshop, Asilomar, CA November 2 - 5, 2006
Gordon Conference on Plant Molecular Biology, Plymouth, NH, July 16–21 2006
Plant Protein Phosphorylation Workshop, Sanibel Island, FL November 3 - 6, 2005
16th International Conference on Arabidopsis Research, Madison, WI, June 15 - 19, 2005
Plant Genomes: From Sequence to Phenome, Dec. 9 – 12, 2004
Auxin 2004 Conference, Kolympari, Greece 5/22 – 5/27/04
Plant Protein Phosphorylation Workshop, Clearwater Beach, FL, 10/23 - 10/26/03
Gordon Conference on Mechanotransduction and Gravity Signaling in Biological Systems,
July 20 -25, 2003
DeLong CV-- 6
Plant Protein Phosphorylation Workshop, Jackson Hole, WY, 10/11 - 10/14/03
Gordon Conference on Plant Biological Regulatory Mechanisms, Plymouth, NH, 7/7 7/12/02
International Conference on Plant Protein Phosphorylation, Vienna, Austria, 9/12/01 9/15/01
12th International Conference on Arabidopsis Research, Madison, WI, 6/23 - 6/27/01
New England Arabidopsis Meeting, Cambridge, MA (bi-monthly regional meeting; talks
presented 10/04/00 and 12/4/03)
Functional Genomics of Plant Phosphorylation Workshop, Breckenridge, CO 10/21 10/24/00
Gordon Conference on Plant Molecular Biology, Plymouth, NH, 7/16 - 7/21/00
Plant Protein Phosphorylation Workshop, Snowbird, UT, 5/27 - 5/30/99
Gordon Conference on Plant Molecular Biology, Henniker, NH, 7/19 - 7/24/98
8th International Conference on Arabidopsis Research, Madison, WI, 6/25 - 6/29/97
Annual meetings, NASA/NSF Joint Program in Plant Biology, Network for Research on
Plant Sensory Systems 9/4 - 9/7/97, 6/4 - 6/7/98 & 3/13 - 3/15/99
LABORATORY PERSONNEL SUPERVISED
Predoctoral students
Donna L. Lizotte, 6/98 - 1/04
Predoctoral rotation students
Lisa R. Williams, spring 1999
Andrew Castiglioni, summer 2000
Aubrey Frank, summer 2005
Yuko Hasegawa, winter 2007
Kyle Skottke, spring 2007
Undergraduate independent research students
David D. McManus, spring 1997 - spring 1998
Elizabeth Gerlach, summer 1998 - spring 1999
Kimberly Hemond, summer 1998 - spring 1999
Todd I. Strochlich, summer 1999 - spring 2000
Jay W. Song, summer - winter 2000
Eric T. Block, summer 2000 - spring 2001
Yvonne Chao, spring 2003 - spring 2004
DeLong CV-- 7
Su-Yang Liu, spring 2003- spring 2004
Michael Clarke-Pearson, fall 2004 – spring 2006
Roland Remenyi, spring 2005 – 2006
Alexander Leydon, spring 2006 – present
Christopher Inra, spring 2007 –
Jorge Rodriguez Barrios summer 2007
Undergraduate summer research students
Hannah R. Cohen, 1997
Albert Siryaporn, 1999
Rona Jia Luo, 2002
Yvonne Chao, 2003
Su-Yang Liu, 2003
Sylvia Cho, 2004
Postdoctoral Associates
Hong-Wei Zhou 6/02 – 2/06
Qin Zhou 9/05 – 3/06
Joshua Blakeslee, 6/06 - present
Research assistants
Michael S. Foulk, 2/98 - 5/00
Cindy Nussbaumer 2/02 - 1/04
Tina Simolari 4/04 – 8/05
Jeffrey Heath 8/05 - present
Visiting (sabbatical) scholar
Prof. Jerry Melaragno, Rhode Island College, spring 2000
SERVICE TO UNIVERSITY
Member MCB Curriculum Committee 09/06 - present
Member MCB Faculty Search Committee (Developmental Biologist) 05/06
Member MCB Faculty Search Committee (Plant Biologist) 03/04
Sc.B. Biology Concentration Advising (9 students; Spring '03 - present)
Member MCB Faculty Search Committee (Developmental Biologist) 02/03
Campus Representative, MCB Graduate Program Executive Committee, 2000
Co-chair, MCB Graduate Program Annual Retreat, 1998 & 1999
Member, MCB Graduate Program Admissions Committee, 1997, 1998, 2002, 2006
Member, Thesis Committees for MCB students Aubrey Frank, Shannon Ballard, Dane
Hazelbaker, Donna Lizotte, Caroline Savery, Marta Radman-Livaja and Ongkar
Khalsa, 1996 – present
Member, Thesis Committee for Pathobiology student Jung-Sun Yoo, 2004
DeLong CV-- 8
TEACHING
Plant Organism (BI 44) Spring 2008 (with Mark Johnson)
BI 203 Fall 2007 (with T. Serio, J. Laney and K. Mowry) Foundations for Advanced Study
in Experimental Biology
BI 203 Fall 2006 (with T. Serio, J. Laney and W. Atwood) Foundations for Advanced
Study in Experimental Biology
Plant Organism (BI 44) Spring 2006 (with Mark Johnson)
Current Topics in Biochemistry and Molecular Biology: Novel Regulatory Mechanisms
(BI 221) Fall 2005 (with Arthur Landy)
Current Topics in Biochemistry and Molecular Biology: Chromatin Regulation of Gene
Expression in Development and Disease (BI 220) Spring 2005 (with Richard
Freiman)
Plant Organism (BI 44) Spring 2004, 2005 (with Carol Reiss)
Guest lectures in Plant Organism (BI 44) 3/31/98 & 4/2/98, 3/11/99 & 3/25/99, 4/4/00,
4/6/00 & 4/11/00, 4/17/01 & 4/19/01, 3/5/02 & 3/7/02
Guest lectures in Signal Transduction and the Cell Cycle (BI 293) 9/30/98 & 9/28/99
Guest lecture in Advanced Cell Biology (BI 105) 10/16/97
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