WISCONSIN
UNIVERSITY OF WISCONSIN–MADISON
www.d2p.wisc.edu
REDI Committee – Board of Regents
By Paul M. DeLuca, Jr. and Mark E. Cook
February 6, 2014
Paul DeLuca
Provost
Medical Physics
Mark Cook
Chair of D2P Advisory Board
Animal Sciences
www.d2p.wisc.edu
UW-Madison’s research engine
UW-Madison research expenditures=$1B
UW discloses 350 inventions/year to WARF
WARF applies for 200 patents per year
WARF has over 50 new license agreements/year
WARF will help spin out 5-7 new companies this
year, impressive but….
• UW-Madison and WARF have identified a gap in
technology transfer
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Raiders and the Lost Ark
$1 billion in research expenditures. Are we missing something?
WISCONSIN
UNIVERSITY OF WISCONSIN–MADISON
Harris_01
WISCONSIN
UNIVERSITY OF WISCONSIN–MADISON
Harris_01
WISCONSIN
UNIVERSITY OF WISCONSIN–MADISON
SHINE
Medical
and
Phoenix
Nuclear
Labs
SHINE Medical and Phoenix Nuclear Labs
Introduction to SHINE Medical Technologies
Health. Illuminated.
• SHINE Medical Technologies™ is dedicated to being the world
leader in safe, clean, affordable production of medical tracers and
cancer treatment elements
• Highest priority is safely delivering a highly reliable, high-quality
supply of the medical ingredients required by nearly 100,000
patients each day
• Spun out of ideas developed at the University of Wisconsin—
Madison
• Will create hundreds of jobs in Janesville, WI, solve a critical global
problem facing the supply of vital medical radioisotopes
Examples
Medical
Isotope
Examples of of
Medical
Isotope
Scans Scans
Approximately 45 million procedures are performed
with medical isotopes each year (> 1 every second)
 Some examples

Stress Test (Cardiac perfusion)
Brain Perfusion
Cancer Screening (Bone scans)
Gall Bladder Function
Alzheimer’s disease
Thyroid Scans
Lung Perfusion
Salivary Gland Scans
Kidney Scan and Function
Meckel’s Scans
Liver Scans
Sentinel Lymph Node
Localization
New Technology is Accelerator based:
New Technology
Accelerator
dramatically is
improves
safety,based:
efficiency
Dramatically improves safety, efficiency
• Accelerator generates only neutrons
and stable helium
• Uranium target reusable; moly-99
separated after several days and
target put back into system
• Radioactive byproducts reduced by
hundreds of times compared to
other production methods
Solid
Progress
to Market
Solid Progress
to Market
• Technology: All elements
demonstrated at full scale
• Regulatory: Major applications filed
and accepted—first since 1961!
• Market: Existing suppliers raising
prices, shortages persisting, supply
agreements with major customers
imminent
• Financing: $30 M spent on project
so far, $150 M remaining to market
Confidential information of Shine Medical
Technologies, Inc.
Inventor Initiated
D2P Shepherds
Scout, Connect, Incubation, Launch
UW ACE
D2P Structure
UW
Madison
WARF
Target Areas – High Potential Technologies
Physical
Sciences/
Engineering
Agriculture
Medical
Devices
Comp.
Science/
Info Tech
Pharma
Other Target
areas
Wisconsin Resources
Mark E. Cook
Chair, D2P Advisory Board
Professor of Animal Sciences
Focuses on nutritional regulation of immune function
Founder of several companies, including Isomark, LLC.
Holds patents related to immunity, body mass and
composition.
D2P Shepherding
An Example of Use of Funds for Economic Development
D2P Goal
• Enable UW-Madison/WARF to:
–Create and grow IP
•That benefits the world
–Is valued by society
»Creates new WI jobs
D2P’s Mission
I. Cultivate entrepreneurship
II. Secure intellectual property
III. Accelerate transfer of campus innovations
IV.Create a sense of urgency in tech transfer
V. Leverage internal and external resources
VI.Expand investment capital and entrepreneurial
talent
VII.Improve UW-Madison/WARF’s 80+ year
collaboration through a new joint venture
D2P Principles of Operation
D2P expert team will:
• Champion innovation and IP protection
• Serve as “go-to” contact for technology
commercialization
• Connect innovators to commercialization
resources
• Act as trusted advisor to UW innovators
D2P Leadership Structure
UW/VCR
WARF
Advisory
Board
Director
D2P Structure
UW
Madison
WARF
Target Areas – High Potential Technologies
Physical
Sciences/
Engineering
Agriculture
Medical
Devices
Comp.
Science/
Info Tech
Pharma
Other Target
areas
Structure for Each Target Area
Target
Area
Advisors
Lead Mentor
in Residence
50% time
PROJECTS
D2P Leadership Understands
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Faculty want to be faculty
Support is needed to mature an idea
Advancement of technology must be seamless
Additional activity must advantage the
research laboratory
The D2P Approach
• Targeted technologies
• Collaborative engagement model
• Maximize leverage of existing resources
• Trusted advisor to guide the way
• “House Calls”
• Mentors-in-Residence
• Accounting skills to support pro-forma
financials
• Public/Private partnership
Campus exit
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Executable business plan
Channel through regulatory
Path to revenue
Assembled leadership team and board
Immediate access to capital
Attractive to venture funding
Igniter
• $2.4 Million provided to “IGNITE” new
companies through D2P
• Funds provided through the System
Incentive Grant program. (Thank you!)
IMPACT on Wisconsin
• Economic development for the State of
Wisconsin
– New companies
– New jobs
– Better prepared workforce
– Increased venture funding