05/11/2015
We will begin momentarily at 2pm ET
Slides available now! Recordings will be available to ACS members after one week.
www.acs.org/acswebinars
Contact ACS Webinars ® at acswebinars@acs.org
1
Have Questions?
“Why am I muted?”
Don’t worry. Everyone is
muted except the presenter
and host. Thank you and
enjoy the show.
Type them into questions box!
Contact ACS Webinars ® at acswebinars@acs.org
2
1
05/11/2015
Have you discovered the missing element?
www.acs.org/2joinACS
Find the many benefits of ACS membership!
3
Benefits of ACS Membership
Chemical & Engineering News (C&EN)
The preeminent weekly news source.
NEW! Free Access to ACS Presentations on Demand®
ACS Member only access to over 1,000 presentation
recordings from recent ACS meetings and select events.
NEW! ACS Career Navigator
Your source for leadership development, professional
education, career services, and much more.
www.acs.org/2joinACS
4
2
05/11/2015
Let’s get Social…post, tweet, and link to
ACS Webinars during today’s broadcast!
facebook.com/acswebinars
@acswebinars
Search for “acswebinars”
and connect!
5
How has ACS Webinars
benefited you?
®
“Advanced Pyrotechnics 2 was a great presentation. It
was well organized and covered a good deal of very
fundamental key descriptions about pyrotechnics. I
really appreciated Chris Mocella emphasizing clubs
and pyrotechnics organizations.”
Paul Smith,
Director of Lecture Demonstrations, Purdue University
Vice President, Pyrotechnics Guild International
Be a featured fan on an upcoming webinar! Write to us @ acswebinars@acs.org
6
3
05/11/2015
facebook.com/acswebinars
@acswebinars
youtube.com/acswebinars
Search for “acswebinars” and connect!
7
Learn from the best and brightest minds in chemistry!
Hundreds of webinars presented by subject matter experts
in the chemical enterprise.
Recordings are available to current ACS members one
week after the Live broadcast date. www.acs.org/acswebinars
®
Broadcasts of ACS Webinars continue to be available to
the general public LIVE every Thursday at 2pm ET!
www.acs.org/acswebinars
8
4
05/11/2015
®
Upcoming ACS Webinars
www.acs.org/acswebinars
Thursday, November 12, 2015
“Chemistry of Addiction”
Anthony Rappé, Professor of Chemistry, Colorado State University
Darren Griffen, Professor of Genetics, University of Kent
Thursday, November 19, 2015
“Prodrugs in Drug Discovery”
John Higgins, Senior Principal Scientist and Network Technology Lead, Merck
Nicholas Meanwell, Executive Director, Discovery Chemistry, Bristol-Myers
Squibb
9
Contact ACS Webinars ® at acswebinars@acs.org
“From Truth Serum to Anesthesia:
The Discovery and Uses of Sodium Thiopental”
Michael Matson
Reservoir Engineer,
Kinder Morgan CO2
David Harwell
Asst. Director of Industry
Member Programs, ACS
Slides available now! Recordings will be available to ACS members after one week
www.acs.org/acswebinars
Contact ACS Webinars at acswebinars@acs.org
10
5
05/11/2015
From Truth Serum to Anesthesia:
The Discovery and Uses of Sodium Thiopental
Michael Matson, Kinder Morgan
Remember, remember, the 5th of November,
The gunpowder treason and plot…
12
6
05/11/2015
Johann Friedrich Wilhelm
Adolf von Baeyer
13
Barbituric Acid
14
7
05/11/2015
Audience Survey Question
ANSWER THE QUESTION ON BLUE SCREEN IN ONE MOMENT
Where do barbiturates get their name?
•
In honor of Adolf von Bayer’s girlfriend, Barbara
•
The urea first used was concentrated from the urine of a dog named
Barbara
•
The molecule was discovered on the day of the Feast of Saint
Barbara
•
The urea first used was concentrated from the urine of a Munich
barmaid named Barbara
15
Saint Barbara
16
8
05/11/2015
Barbital
Josef von Mering
Hermann Emil Fischer
17
Audience Survey Question
ANSWER THE QUESTION ON BLUE SCREEN IN ONE MOMENT
Where does the drug Veronal get its name?
•
The drug makes you sleepy, and the city of Verona was considered
the most tranquil city in Europe
•
Von Mering was on vacation in Verona when he got a telegram from
Emil Fischer about the drug’s discovery
•
Stems from the Latin root “verum” meaning ‘truth’
•
The discovery was celebrated over a bottle of wine made from veron
grapes
18
9
05/11/2015
Veronal
19
Obtained from the site http://www.wellcomeimages.org/ and is under the Creative Commons Attribution only license CC BY 4.0
Audience Survey Question
ANSWER THE QUESTION ON BLUE SCREEN IN ONE MOMENT
Which celebrity’s death was NOT due to barbiturate overdose?
•
Judy Garland
•
Jimi Hendrix
•
Michael Jackson
•
Marilyn Monroe
•
None. All of the above died of barbiturate overdose.
20
10
05/11/2015
Nembutal
21
Pentothal
Transferred from Flickr by User:JohnnyMrNinja using flickr2commons
22
11
05/11/2015
Liquid Anaesthetics
Credit: Science Museum, London. Wellcome Images images@wellcome.ac.uk http://wellcomeimages.org
23
WWII
24
12
05/11/2015
Narcoanalysis
25
This is an image from the Nationaal Archief, the Dutch National Archives, and Spaarnestad Photo, donated in the context of a partnership program.
Audience Survey Question
ANSWER THE QUESTION ON BLUE SCREEN IN ONE MOMENT
Which of the following is true about “Truth Serum”?
•
The term "truth serum" came onto the scene in the 1920’s.
•
Confessions of guilt under the influence of truth serum were ruled in
admissible in US courts in 1963.
•
Scopolamine, Pentothal, Sodium Amytal, and Ethyl Alcohol have all
been used as “truth serums.”
•
“Truth serums” don’t insure the truth but instead disorient and
create positive feelings that make lying more difficult.
•
All of the above are true.
26
13
05/11/2015
Truth Serum
27
Sodium Amytal
Credit: Science Museum, London. Wellcome Images images@wellcome.ac.uk http://wellcomeimages.org
28
14
05/11/2015
Lethal Injection
29
Hospira
This file is licensed under the Creative Commons Attribution 3.0 Unsupported license. Attribution: Acherubini2020 at en.wikipedia
30
15
05/11/2015
Propofol
"Ampoule prefilled JPN" by ignis - Own work. Licensed under CC BY-SA 3.0 via Wikimedia Commons https://commons.wikimedia.org/wiki/File:Ampoule_prefilled_JPN.jpg#/media/File:Ampoule_prefilled_JPN.jpg
31
“From Truth Serum to Anesthesia:
The Discovery and Uses of Sodium Thiopental”
Michael Matson
Reservoir Engineer,
Kinder Morgan CO2
David Harwell
Asst. Director of Industry
Member Programs, ACS
Slides available now! Recordings will be available to ACS members after one week
www.acs.org/acswebinars
Contact ACS Webinars at acswebinars@acs.org
32
16
05/11/2015
How has ACS Webinars
benefited you?
®
“Advanced Pyrotechnics 2 was a great presentation. It
was well organized and covered a good deal of very
fundamental key descriptions about pyrotechnics. I
really appreciated Chris Mocella emphasizing clubs
and pyrotechnics organizations.”
Paul Smith,
Director of Lecture Demonstrations, Purdue University
Vice President, Pyrotechnics Guild International
Be a featured fan on an upcoming webinar! Write to us @ acswebinars@acs.org
33
facebook.com/acswebinars
@acswebinars
youtube.com/acswebinars
Search for “acswebinars” and connect!
34
17
05/11/2015
Benefits of ACS Membership
Chemical & Engineering News (C&EN)
The preeminent weekly news source.
NEW! Free Access to ACS Presentations on Demand®
ACS Member only access to over 1,000 presentation
recordings from recent ACS meetings and select events.
NEW! ACS Career Navigator
Your source for leadership development, professional
education, career services, and much more.
www.acs.org/2joinACS
35
®
ACS Webinars does not endorse any products or
services. The views expressed in this
presentation are those of the presenter and do
not necessarily reflect the views or policies of the
American Chemical Society.
Contact ACS Webinars ® at acswebinars@acs.org
36
18
05/11/2015
®
Upcoming ACS Webinars
www.acs.org/acswebinars
Thursday, November 12, 2015
“Chemistry of Addiction”
Anthony Rappé, Professor of Chemistry, Colorado State University
Darren Griffen, Professor of Genetics, University of Kent
Thursday, November 19, 2015
“Prodrugs in Drug Discovery”
John Higgins, Senior Principal Scientist and Network Technology Lead, Merck
Nicholas Meanwell, Executive Director, Discovery Chemistry, Bristol-Myers
Squibb
Contact ACS Webinars ® at acswebinars@acs.org
37
19