Granulocytes
Innate Immunity · Acute phase proteins · Western blot · Antimicrobial peptides · Complement Research ·
LPS, Microbial toxins · Flow cytometry · Scavenger receptors · TLR · Assays · Inflammation · Adhesion molecules ·
Immunohistochemistry · Coagulation molecules · Cytokines · Chemokines · Antibodies · Cell & Tissue damage ·
Functional studies · Lipid binding proteins · Immunoprecipitation · Oxidative stress · Organ & Tissue related research ·
Proteins · Unique
products
www.hycultbiotech.com
General introduction
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate
immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase
proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by
pathogens or oxidation factors.
Granulocytes
Basophils, eosinophils and neutrophils
are the three cell types that belong to the
granulocytes. Granulocytes are a type
of white blood cells characterized by the
presence of granules in their cytoplasm.
The nucleus shaped into the usual three
lobes are typical for a granulocyte.
They are released by bone marrow under
the influence of complement through a
process called granulopoiesis.
Activation of granulocytes play a central
role in the pathogenesis of many
autoimmune diseases and are an
important clinical hallmark for acute
inflammation, sepsis and allergic
conditions. Granulocytes form the first
line of defense to many pathogens by
releasing antimicrobial peptides.
In this Product Leaflet the following
abbreviations for the applications and
cross reactivity have been used:
FC: Flow Cytometry
FS: Functional studies
IA:Immunoassays
IF:Immunofluorescence
IHC:Immunohistochemistry
F: Frozen sections
P: Paraffin sections
IP: Immunoprecipitation
W: Western Blot
More information about products within
the field of Innate Immunity, Antimicrobial
peptides, Microbial toxins, TLR,
Inflammation, Cell & Tissue damage,
Lipid binding proteins and Oxidative
stress can be found on our website.
Please feel free to subscribe to our
newsletter to remain up-to-date on
Hycult Biotech’s product information!
If you have any questions regarding
pricing and ordering, please contact your
local distributor. Distributor information
can be found on our website.
Figure 1: A blood smear showing a basophil surrounded by
erythrocytes
Figure 2: A blood smear showing a neutrophil stained with
Wright’s stain
Hycult Biotech has worldwide distribution
through a network of over 45 distributors.
We believe technical support is essential
when using our products or when looking
into buying them for your research needs.
For product specific information
please visit our website:
www.hycultbiotech.com or contact us
on support@hycultbiotech.com.
Figure 3: An eosinophil from a peripheral blood smear
Assays
Proteins/Peptides
Product
Quantity Cat.#
Product
Quantity Cat.#
Calprotectin, Human
Elafin (Trappin-2), Human
Elastase, Human
HNP 1-3, Human
Lactoferrin, Human
LL-37, Human
MPO, Human
MPO, Mouse
MPO, Rat
S100A9/Calprotectin, Mouse
1 x 96 det.
1 x 96 det.
1 x 96 det.
1 x 96 det.
1 x 96 det.
1 x 96 det.
1 x 96 det.
1 x 96 det.
1 x 96 det.
1 x 96 det.
HK325
HK318
HK319
HK317
HK329
HK321
HK324
HK210
HK105
HK214
Alpha-Defensin 5, Human
Calprotectin, Human, Recombinant
Elafin, Human, Recombinant
HNP1-3, Human, Natural
LL-37/CAP-18, Human
50 µg
50 µg
50 µg
100 µg
50 µg
HC2121
HC2120
HC4011
HC4014
HC4013
Antibodies
Product Name
Clone name
Application
Quantity
Cat. #
Apoptotic Neutrophils, Human
Azurocidin, Human
Azurocidin, Human
Azurocidin, Human
Basophils, Human
Beta-defensin 2, Human
Calprotectin, Human
CD200R3, Mouse
CD200R3, Mouse
CR1/CR2, Mouse
Defensin 5, Human
Elafin, Human
Elafin, Human
Elafin, Human
Elastase, Human
Elastase, Human
HNP1-3, Human
Lactoferrin, Bovine
Lactoferrin, Bovine
Lactoferrin, Bovine Lactoferrin, Human
Lactoferrin, Human
LL-37/CAP-18, Human
LL-37/CAP-18, Human
LPLUNC1, Mouse
Lysozyme, Human
Neutrophil defensin 5, Rabbit
Neutrophils, Mouse
Proteinase 3, Human
Proteinase 3, Human
RBC, Mouse
RNAse 7, Human
RNAse 7, Human
SIRL-1, Human
SPLUNC1, Human
SPLUNC1, Human
SPLUNC1, Mouse
TREM-1, Human
BOB93
z6718
z6721
z6733
2D7
pAb
27E10
Ba91
Ba103
7E9
8C8
pAb
TRAB2F
TRAB2O
265-3K1
pAb
D21
a-bC-lobe
pAb
5F12.1.2
pAb
265-1K1
3D11
1-1C12
pAb
pAb
R3
NIMP-R14
WGM2
PR3-G2
34-3C
3C2
4F9
1A5
5F5B12
5F5G1
pAb
6B1
FC W
F IF W
IA W
IA W
FC F IF P W
IA P W
FC F IA IP P W
FC FS IP
FC FS IP W
FC IF IP W
F IA W
P W
IA P W
IA P W
IA W
IA
FC F FS IA IF IP P W
IA W
IA IP W
IA W
IA IP W
F IA W
FS IF P W
IA IF P W
P W
IA IP W
FC F IA P W
FC F FS IA P
FC F FS IA P W
FC F IA W
FC FS
F IA P W
F IA P W
FC FS IP W
F IA IF W
F IA IF W
P W
FC FS IA W
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg 100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
HM2154
HM2312
HM2310
HM2311
HM2279
HP9057
HM2156
HM1104
HM1103
HM1112
HM2228
HP9025
HM2063
HM2062
HM2174
HP9027
HM2058
HM4013
HP7001
HM4012
HP9034
HM2173
HM2070
HM2071
HP8044
HP9035
HM4008
HM1039
HM2171
HM2172
HM1120
HM2316
HM2317
HM2309
HM2314
HM2315
HP8043
HM2252
Figure 4: Alpha-Defensin 5 coloring on a healthy human
ileum using a paraffin section (Cat. # HM2228)
Figure 5: Immunochemistry analysis of LL-37 antibody
(Cat. # HM2070)
Figure 6: Immunohistochemical staining of Elafin with
anti-Elafin pAb on paraffin section of psoriatic human skin
tissue (Cat. # HP9025)
Figure 7: Immunohistochemical staining with Calprotectin
antibody using a paraffin section (Cat. # HM2156)
Why scientists buy our products:
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Unique products
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Sensitivity
Standardized assays
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Specificity
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Quality control
Easy to use
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Value for money
Inter/intra variation <10%
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1- & 2-plate kits
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Functional studies
Well documented products
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Technical support
Broad in applications
Hycult Biotech is distributed by:
www.hycultbiotech.com
Hycult Biotech B.V.
Frontstraat 2A
5405 PB Uden
The Netherlands
T +31(0)413 251335
F +31(0)413 248353
E info@hycultbiotech.com
Hycult Biotech Inc.
600 West Germantown Pike
Suite 110
Plymouth Meeting, PA 19462
USA
T: +1 484 5343566 Toll Free: 855-2-HYCULT (855-2-492858)
F: +1 484 3683558
E: orders-us@hycultbiotech.com
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