PROGRAM
CONFERINTA MEDICINA TRANSLATIONALA
desfasurata in cadrul celui de-al X-lea SIMPOZION ACADEMICIAN NICOLAE CAJAL
1 – 4 APRILIE 2015
HOTEL NOVOTEL CITY CENTER, BUCURESTI
MIERCURI, 1 APRILIE 2015
16.30 – 18.30 Inscriere participanti
Foyer Sala Paris
18.30 – 19.00 Deschidere Oficiala
Prof. Dr. Irinel Popescu – Presedinte Academia de Stiinte Medicale
Prezentare proiect POSDRU 186/3.2/S/155295 „DEZVOLTAREA COMPETENTELOR IN
TRANSPLANT”
Irina Cajal Marin – Presedinte Fundatia Academian Nicolae Cajal
Prof. Stefan Constantinescu - Ludwig Institute for Cancer Resarch and Université
catholique de Louvain, de Duve Institute, B1200 Brussels
Nicolae Banicioiu – Ministrul Sanatatii
Cristian Marius Hera – Vicepresedinte Academia Romana
Vasile Salaru – Secretar de Stat, Ministerul Educatiei si Cercetarii Stiintifice
19.00
Cocktail Deschidere Oficiala
Foyer Sala Paris
JOI, 2 APRILIE 2015
08.30 – 10.30 SESIUNE ACADEMIA DE STIINTE MEDICALE – I
Moderatori: Mihai Coculescu, Leon Zagrean
08.30 – 09.00 Dinamica mitocondriala si dialogul molecular dintre mitocondrii si organitele
intracelulare; semnificatii in miocardul diabetic
Doina Popov (1)
(1) Institutul de Biolologie si Patologie Celulara, Academia Romana
09.00 – 09.30
Migratia populatiilor antice explica mapa genetica a Europei: comparatie cu
migratiile actuale studiate de programul MEDIGENE
Florin Grigorescu (1), Mihail Coculescu (2), Ramon Gomis (3)
(1) Universitatea Montpellier, IURC Montpellier
(2) UMF Carol Davila Bucuresti, Endocrinologie
1
(3) Universitatea Barcelona, Endocrinologie
09.30 – 10.00 Studii transculturale in intestinul iritabil. Sunt romanii diferiti?
Dan Lucian Dumitrascu
UMF Iuliu Hatieganu, Cluj Napoca, Gastroenterologie
10.00 – 10.30 Aplicatii ale endoscopiei interventionale si chirurgiei endoscopice transluminale
Adrian Saftoiu
Universitatea de Medicina si Farmacie din Craiova, Chirurgie
10.30 – 11.00 Celulele Langerhans: 147 ani de la descoperirea lor
Constantin Ionescu-Tirgoviste (1,2), Sabina Zurac (1), Cristian Guja (1,2), Costin
Căruntu, Paul Gagniuc (2), Mihaela Ghita ( 1)
(1) UMF “C. Davila”, Bucuresti, Romania;
(2) Institutul Național de Diabet, Nutiritie si Boli Metabolice N.C. Paulescu,
Bucuresti
11.00 – 11.30 PAUZA DE CAFEA
11.30 – 13.00 SESIUNE ACADEMIA DE STIINTE MEDICALE – II
Moderatori: Eduard Apetrei, Florin Grigorescu
11.30 – 12.00 Impactul clinic al cardiologiei moleculare
Eduard Apetrei
UMF Carol Davila Bucuresti, Institutul de Cardiologie, Fundeni
12.00 – 12.30 Cuantificarea modificarilor subtile cardiovasculare in acromegalie: aportul
imagisticii cardiace modern
Ruxandra Jurcut, Anca Florian, Simona Galoiu, Aurora Vladaia, Mihail Coculescu,
Carmen Ginghina
UMF Carol Davila Bucuresti, Cardiologie si Endocrinologie
12.30-13.00
Riscul reactivarii virusului hepatitei B si C in era terapiilor biologice
Coman Tanasescu
UMF Carol Davila, Clinica Medicala Colentina
13.00 – 14.00 PAUZA DE PRANZ
14.00 – 16.00 SESIUNE ACADEMIA DE STIINTE MEDICALE – III
Moderatori: Constantin Mircioiu, Mihail Coculescu
14.00 – 14.30 In vitro assesment of novel tumor cells death mechanism – enucleation.
Paunescu Virgil, Bojin Florina, Ivan Alexandra, Cristea Mirabela, Taculescu Alina,
Gavriliuc Oana, Tanasie Gabriela, Panaitescu Carmen, Tatu Calin.
“Victor Babes” University of Medicine and Pharmacy Timisoara, Romania
2
14.30 – 15.00 Intereferente moleculare in determinarea tireoglobulinei, un risc pentru
ghidurile de consens in endocrinologie
Mariana Purice (1), Mihail Coculescu (2)
(1) Institutul National de Endocrinologie ”C.I.Parhon”, Bucuresti
(2) Academia Romana
15:00 – 15.30 Noi cai de semnalizare intre microbiota intestinala si celulele enteroendocrine
Catalin Chimirel, Fiona Gribble, Frank Reimann
Institute of Metabolic Science and MRC Metabolic Diseases Unit, University of
Cambridge, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0QQ, UK
15:30 – 16:00 Aplicatii ale nanomaterialelor in detectia electrochimica pe probe biomedicale
si de mediu
Robert Sandulescu , Cecilia Cristea, Mihaela Tertiş, Andreea Cernat, Adela
Maghear, Bogdan Feier, Anca Florea, Luminița Fritea
UMF Cluj Napoca
16.00 – 16.30 PAUZA DE CAFEA
16.30 – 18.30 SESIUNE ACADEMIA DE STIINTE MEDICALE – IV
Moderatori: Mihai Hinescu, Nicolae Manolescu
16.30 – 17.00 Personalized/Precision Medicine – Transdisciplinary and translational approach;
Omics Technology
Cristiana Tanase (1,2), Cristian (1), Radu Albulescu (3,2,1)
(1) ”Titu Maiorescu” University, Faculty of Medicine, Bucharest, Romania
(2) ”Victor Babes” National Institute of Pathology,Proteomics, Bucharest, Romania
(3) National Institute for Chemical Pharmaceutical Research and Development,
Bucharest, Romania
17.00 - 17:30 Profilul proteomic al carcinomului tiroidian diferentiat
Felicia Antohe (1), Elena Uyy (1), Viorel-Iulian Suica (1), Raluca Maria Boteanu (1),
Dana Manda (2), Maya Simionescu (1), Corin Badiu (2)
(1) Institutul de Biologie si Patologie Celulara “Nicolae Simionescu”, Bucuresti,
Romania
(1) Institutul National de Endocrinologie ”C.I.Parhon”, Bucuresti, Romania
17.30 -18.00 Expresia, localizarea si functia RAGE in celule de melanom cu diferite grade de
malignitate
Ioana Popa, Elena Ganea, and Stefana Petrescu
Institutul de Biochimie al Academiei Romane, Departamentul de Biologie
Moleculara si Celulara, Bucuresti, Romania.
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18.00 – 18.30 Correlation between tryptase-positive mast cells’s density and h.pylori
presence in gastric neoplasia
Gianina Micu (1), Alexandra Bastian (1,2), Mirela Petre (1), Alexandra-Simona
Iacob (1), Maria Bosa (1), Teodor Voiosu (2,3)
(1) “Colentina” Clinical Hospital, Department of Pathology, Bucharest, Romania
(2) “Carol Davila” University of Medicine, Bucharest, Romania
(3) “Colentina” Clinical Hospital, Department of Gastroenterology, Bucharest,
Romania
VINERI, 3 APRILIE 2015
08.30 – 10.30 Sesiune Medicina moleculara. Aplicatii in boli infectioase si boli cronice
Moderatori: Carmen Diaconu
08.30 – 09.00 Signaling Cross-Talk between Type I Interferon and Thrombopoietin Signaling:
Relevance for Cytokine Therapies and Myeloid Neoplasms
Stefan N. Constantinescu (1), Jean-Philippe Defour (1), Thomas Michiels (2), Jean
Luc Villeval (3), Isabelle Plo (3), William Vainchenker (3), Judith Staerk (4) and
Christian Pecquet (1)
(1) Ludwig Institute for Cancer Resarch and Université catholique de Louvain, de
Duve Institute, B1200 Brussels
(2) VIRO Unit, Duve Institute, Université catholique de Louvain, de Duve Institute,
B1200 Brussels
(3) INSERM U1009 , Institut Gustave Roussy, Villejuif, France
(4) EMBL Nordic Partnership, University of Oslo, Center for Molecular Medicine,
Norway
09.00 – 09.30 Predictive power of polygenic risk score in bipolar disorder in the Romanian
population
Maria Grigoroiu-Serbanescu (1), Carmen C. Diaconu (2), Ana Neagu (2), David
Curtis (3)
(1) Alexandru Obregia Clinical Psychiatric Hospital, Bucharest
(2) Stefan S NicolauInstitut of Virology, Romanian Academy, Bucharest, Romania
(3) University College London, Dept. Psychiatry, London
09.30 – 09.40 Potential molecular targets for gastric cancer therapy
Necula Laura G (1), Chivu-Economescu M (1), Dragu DL(1), Bleotu C (1), Dima SO
(2), Constantinescu G (3), Popescu I (3), Diaconu CC (1)
(1) Stefan S Nicolau Institute of Virology, Romanian Academy, Bucharest,
Romania
(2) Center of Digestive Disease and Liver Transplantation, Fundeni Clinical
Institute, Bucharest, Romania
(3) Floreasca Emergency Clinical Hospital, Bucharest, Romania
09.40 – 09.50 New isoniazid derived hydrazones with anti-tubercular activity
4
Lilia Matei (1,2), Ioana Madalina Aldea (1), Coralia Bleotu (1), Irina Zarafu (2),Ion
Baciu (2), Anamaria Hanganu (2), Otilia Banu (3), Petre Ionita (2), Anca Paun (2),
Arnaud Tatibouët (4), Carmen Cristina Diaconu (1)
(1) Stefan S Nicolau Institute of Virology, Romanian Academy, Bucharest,
Romania
(2) Faculty of Chemistry, University of Bucharest, Romania
(3) Institute of Cardiovascular Diseases Prof. Dr. C.C. Iliescu, Microbiology
Department, Bucharest, Romania
(4) University of Orleans, ICOA-UMR7311, CNRS, France
09:50 – 10:00 Preliminary research on cytotoxicity and antiviral activity of some natural
bioactive compounds.
Ioana M. Aldea (1), Daniela Ionescu (2), Coralia Bleotu (1), MihaelaChivu
Economescu (1), Lilia Matei (1), Iuliana Crisan (2), Stefan Stangaciu (3), Daniela A.
Ion (4,5), Carmen C. Diaconu (1)
(1) Stefan S. NicolauInstitute of Virology, Bucharest,Romania
(2) S.C. Hofigal Export Import S.A., Bucharest,Romania
(3) Apitherapy Consulting & Trading International Ltd., Romania
(4) Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
(5) Prof. dr. MateiBalş National Institute of Infectious Diseases, European
HIV/AIDS Academy, Bucharest, Romania
10:00 – 10.10 Role of interleukine-17 (IL-17) in renal and cardiovascular damage in systemic
lupus erythematous
Adriana Metoni (1), Paul Balanescu (1,2), Carmen C Diaconu (3), Dumitru
Matei(1,4), CristianBaicus (1,2,5)
(1) Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
(2) Laboratory of Immunology, Colentina Research Center, Bucharest, Romania
(3) Stefan S. Nicolau Institute of Virology, Bucharest, Romania
(4) Institute of Mother and Child “Prof. Alfred Russescu”, Bucharest, Romania
(5) Internal Medicine Clinic, Colentina Clinic Hospital, Bucharest, Romania
10:10 – 10:20 Dezvoltarea infrastructurii de cercetare prin modernizarea centrului pentru
studiul ocogenezei si al utilizarii oncolizei virale ca strategie terapeutica –
ONCOVIR - FEDR – POSCCE Axa II, operatiunea 2.2.1. Proiect nr. 929, SMIS
14049.
10:20 – 10:30 Utilitatea clinica a screeaningului si detectiei timpurii a markerilor tumorali
Dr Ana-Maria Georgescu
Novaintermed
10.30 – 11.00 PAUZA DE CAFEA
11.00 – 13.00 SESIUNE ACTUALITATI IN VIRUSOLOGIE – I
Moderatori: Simona Ruta
5
11:00 – 11:20 Un nou profil epidemiologic al rujeolei In Romania
Cernescu Costin
Institutul de Virusologie St. S. Nicolau, Academia Romana
11:20 – 11:40 Epidemia HIV/SIDA in Romania - dupa 25 de ani
Adrian Streinu Cercel
Institutul de Boli Infectioase Matei Bals
11:40 – 11:55 Subtipuri HIV in Romania la pacienti cu infectie nou diagnosticata
Aura Temereanca, Claudia Dita
Institutul de Virusologie St. S. Nicolau, Academia Romana, Bucuresti, Romania
11:55 – 12.10 Prezentari tardive in infectia HIV la utilizatorii de droguri intravenoase
Ianache Irina (1), Ceausu Emanoil (1,2), Ruta Simona (2,3), Erscoiu Simona (1,2),
Radoi Roxana (1), Tardei Gratiela (1), Oprea Cristiana (1,2)
(1) Spitalul Clinic de Boli Infectioase si Tropicale “Victor Babes”, Bucuresti,
Romania
(2) Universitatea de Medicina si Farmacie“Carol Davila”, Bucuresti, Romania
(3) Institutul de Virusologie St. S. Nicolau, Bucuresti, Romania
12:10 – 12:25 Malformatii congenitale severe la nou nascutii din mame HIV positiveexperienta Institutului National de Boli Infectioase Matei Bals
Ana Maria Tudor (1,2), Mariana Mărdărescu (2), Ioana Alina Anca (1,3), Cristina
Petre (2), Cosmina Cristea (1), Ruxandra Neagu Drăchicenoiu (2), Rodica
Ungurianu (2)
(1) „Carol Davila” University for Medicine and Pharmacy, Bucharest
(2) „Matei Bals” National Institute for Infectious Diseases, Bucharest
(3) „ Alfred Rusescu” Institutefor Mother and Child Protection, Bucharest
12.25 – 12.40 Corelatii intre disfunctiile metabolismului glucidic si adipokine la pacienti
HIV pozitivi sub tratament antiretroviral
Catalin Tiliscan1,2, Victoria Arama1,2,Raluca Mihailescu2, Daniela Munteanu2,
Adrian Streinu-Cercel1,2, Daniela Adriana Ion1, Ana Maria Tudor1,2, Cristina
Popescu1,2, Anna Tartakovsky1, Stefan Sorin Arama1
1
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania;
2 Prof. Dr. Matei Bals National Institute of Infectious Diseases, Bucharest,
Romania
12:40 – 12:55 Corelatii intre expresia miRNA- 29 si markerii inflamatori in cursul infectiei HIV
cronice
Adelina Rosca1, Luminita Ene2, Gabriela Anton3, Iulia Iancu3,Claudia Dita3,
Carmen Diaconu3, Aura Temereanca1,3, Cristian Achim4, Simona Ruta1,3.
1
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
2
Dr Victor Babes Hospital for Infectious and Tropical Diseases, Bucharest, Romania
6
3
4
Stefan S. Nicolau Institute of Virology, Bucharest, Romania..
University of California San Diego, La Jolla, USA.
12: 55 – 13.10 Hepatitis B Virus M glycoprotein rescues the viral secretion under stress
condition
Catalin Lazar, Mihaela Uta, Norica Nichita
Institute of Biochemistry of Romanian Academy, Bucharest, Romania
13.10 – 14.00 PAUZA DE PRANZ
14.00 – 16.00 SESIUNE ONCOGENOMICA – I
Moderatori: Dan G Duda, Mircea Ivan
14:00 – 14:30 Personalizing targeted therapies for cancer: Current progress and perspective.
Dan G. Duda
Edwin L. Steele Laboratory for Tumor Biology Department of Radiation Oncology,
Massachusetts General Hospital, USA
14:30 – 15:00 Hypoxia-Regulated Noncoding RNAs: Fine-Tuning the Molecular Landscape in
Cancer
Mircea Ivan
Department of Medicine Division of Hematology/Oncology, Department of
Microbiology and Immunology, Indiana Univesity School of Medicine, USA
15:00 – 15:30 Novel imaging techniques and their potential for individualizing cancer
treatments.
Anca Grosu
Department of Radiation Oncology, Medical Center - University of Freiburg,
Germany
15:30 – 16:00 REMODELING CYTOKINE RECEPTOR DIMERS BY TARGETING JUXTAMEMBRANE
DOMAINS AND ASSEMBLING COMPLEXES USING NOVEL LIGANDS
Stefan N. Constantinescu (1), Vitalina Gryshkova (1), Christian Pecquet (1), JeanPhilippe Defour (1), Emilie Leroy (1), Steven O. Smith (2), Ignacio Morega (3), K.
Christopher Garcia (3)
(1) Ludwig Institute for Cancer Research and Université catholique de Louvain, de
Duve Institute, B1200 Brussels, Belgium
(2) Department of Biochemistry, SUNY Stony Brook University, Long Island, NY,
USA
(3) Department of Biochemistry and Structural biology, Stanford University, CA,
USA
16.00 – 16.30 PAUZA DE CAFEA
16.30 – 18.30 SESIUNE ONCOGENOMICA – II
7
Moderatori: Prof. Tudorel Ciurea, Daniel Danila, Anca Grosu
16:30 – 17.00 Qualifing blood-based molecular assays for targeted therapies in prostate
cancer: from clinic to bench and back to clinic.
Daniel Danila
Memorial Sloan Kettering Cancer Center
17:00 – 17:20 Prognostic and therapeutic significance of liver enriched transcription factor
HNF4alpha expression in hepatocellular carcinoma
Razvan Iacob, Speranta Iacob, Nastase Anca, Raluca Florea, Vlad Herlea, Adina
Croitoru, Simona Dima, Cristian Gheorghe, Liana Gheorghe, Michael Ott, Irinel
Popescu
17: 20 – 17.40 Studii Genetice in patologia tumorala pancreatica
Dan Ionut Gheonea, Adrian Saftoiu, Tudorel Ciurea
Centrul de Cercetare in Gastroenterologie si Hepatologie
UMF Craiova
17.40 – 18.00 Factors involved in β-catenin gene expression deregulation in pancreatic cancer
Anca Botezatu (1), Iulia V. Iancu (1), Adriana Plesa (1), Gabriela Anton (1), Raluca
Florea (2), Veronica Ilie (2), Andrei Sorop (2), Nicolae Bacalbasa (3), Valeria Tica
(2), Simona Dima (2), Irinel Popescu (2)
(1) Institutul de Virusologie Stefan Nicolau
(2) Institutul Clinic Fundeni
(3) UMF Carol Davila
18:00 – 18:20 Disjunction of Dopachrome Tautomerase and Tyrosinase expression in
melanocytic lesions - molecular events and patterns with possible implications
in melanoma progression.
Anca Filimon (1), Sabina A Zurac (2), Adina L Milac (3), Livia E. Sima (1), Stefana M
Petrescu (1), Gabriela Negroiu (1).
(1) Institute of Biochemistry of the Romanian Academy, Department of Cellular
and Molecular Biology, Bucharest, Romania
SAMBATA, 4 APRILIE 2015
08.30 – 10.30 SESIUNE ACADEMIA DE STIINTE MEDICALE – V
Moderatori: Al. Vlad Ciurea, Leon Zagrean
08:30 – 09:00 Motility or morbidity in neurosurgery
A.V. Ciurea, H. Moisa
UMF Bucuresti
09:00 – 09:30 Spectrul functional cerebral al oxitocinei
8
Leon Zagrean, Ana-Maria Zagrean, Anca Panaitescu, Ioana F.Grigoras, Gheorghe
Peltecu
UMF Bucuresti
09:30 – 10:00 Rebalancing cytokine levels with the use of haemoadsorption device in severe
acute respiratory distress syndrome after liver transplatation. A case report
Dana Tomescu (1,3), Mihai Popescu (3), Simona Dima (2), Irinel Popescu (2,3)
(1) Clinica ATI 3 Institutul Clinic Fundeni
(2) Centrul de Chirurgie Digestiva si Transplant Hepatic “Dan Setlacec”
(3) UMF ‘Carol Davila’ Bucuresti, Romania
10.00 – 10.30
Deletia rs199508964 din exonul 6 al genei IRF5 se coreleaza cu polimorfismul
genei IL28B rs12980275 si prezice raspunsul virusologic sustinut la pacientii cu
hepatita recurenta C post-transplant hepatic
Speranta Iacob (1), Razvan Iacob (1), Codruta Vagu (1,3), Simona Ruta (2), Cristian
Gheorghe (1), Liliana Paslaru (1,3), Irinel Popescu (1) and Liana Gheorghe (1)
(1) Institutul Clinic Fundeni
(2) Institutul de Virusologie “Stefan N. Nicolau”
(3) UMF Carol Davila
10.30 – 11.00 PAUZA DE CAFEA
11.00 – 13.00 SESIUNE ACADEMIA DE STIINTE MEDICALE – V
Moderatori: Irinel Popescu, Mihail Coculescu
11.00 – 11.20 Cancerul tiroidian diferentiat: intre genetica si epigenetica
Sorina Schipor (1), Suzana Vladoiu (1), Andra Caragheorgheopol (1), Dana Manda
(1) Sabina Oros (1,2), Andrei Goldstein (1), (1) Dumitriu Ioachim, (2) Cosmin
Giulea, (1,2) Corin Badiu
(1) Institutul de Endocrinologie C.I.Parhon, Bucuresti, Romania
(2) Universitatea de Medicina si Farmacie « Carol Davila », Bucuresti, Romania
11.20 – 11.40 Liposomii tinta senzitivi transportori de antagonisti de receptori chemokinici
CCR2 inhiba metastazarea celulelor tumorale
Manuela Calin (1), Daniela Stan (1), Marko Robleck (2), Lubor Borsig (2), Maya
Simionescu (1)
(1) Institutul de Biologie si Patologie Celulara "Nicolae Simionescu", Bucuresti,
Romania
(2) Institutul de Fiziologie, Universitatea din Zürich, Elvetia
11.40 – 12.00 Moartea cardiac subita corde indemno: intre blestem si binecuvantare
In memoriam Stewart G. Wolf, MD (1914 - 2005)
Prof. Dr. Radu Negoescu, Institutul National de Sanatate Publica, Bucuresti
12.00 – 12.20 Importanta biomarkerilor in diagnosticul bolii Alzheimer,
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Cătălina Tudose (1), Cristina Popescu (2), Magdalena Budișteanu (3), Ioan
Codorean (4), Roxana Dinu (5), Ana Giurgiuca
(1) Profesor Disciplina Psihiatrie, UMF "Carol Davila",
(2) Psiholog, Cercetător gr. III, Spitalul Clinic de Psihiatrie "Prof. Dr. Alex.
Obregia",
(3) Medic Primar Neurologie Pediatrică, cercetător gr. III, Spitalul Clinic de
Psihiatrie "Prof. Dr. Alex. Obregia",
(4) Profesor, Disciplina Imagistică și Medicină Nucleară,
(5) Psiholog, Lector Disciplina Psihologie, Univ. "Spiru Haret"
12.20 – 13:00 CEREMONIE DE INCHIDERE / PREMIILE HERBERT BERLER BARBU
POSTERE
1. Identitatea dupa mastectomie
Iulia Mihaela Iacob (1), Carmen Giuglea (1), Crenguta Coman (2), S. Dumitrache (2), I. P.
Florescu (3)
(1) Spitalul Clinic de Urgenta “Sf. Ioan”, UMF Carol Davila, Bucuresti
(2) Spitalul Clinic de Urgenta “Sf. Ioan”, Bucuresti
(3) Spitalul Clinic de Urgenta “Bagdasar Arseni”, Bucuresti
2. Effect of β-cyclodextrinsbased nanosponges on the solubility of pharmacological active
substances
Andreea Alexandra Olteanu, Corina-Cristina Arama, Crina Maria Monciu
University of Medicine and Pharmacy “Carol Davila” Bucharest, Department of Analytical
Chemistry, Romania
3. Complications of syndactyly release by a modified flatt method
Doina-Iulia Nacea (2), D.M Enescu (1,2), Simona Stoicescu (1,2)
(1) Plastic Surgery and Reconstructive Microsurgery Clinic, Clinical Emergency Hospital
Grigore Alexandrecu”, Bucharest
(2) “Carol Davila ” University of Medicine and Pharmacy, Bucharest
4. Molecular characterization of SCCmec among Methicillin-resistant Staphylococcus
aureus clinical strains isolated from diferent specimens and infections occurred in
patients with cardiovascular surgery
Otilia Banu (1), Bogdan Ionescu (2), Diana Ionescu (2), Irina Gheorghe (2), Ani Ioana
Cotar (3), Grigore Mihaescu (2), Mariana Carmen Chifiriuc (2), Coralia Bleotu (4)
(1) Emergency Institute of Cardiovascular Diseases “Prof. Dr. C.C. Iliescu”, Bucharest
(2) Faculty of Biology, University of Bucharest; Research Institute of the University of
Bucharest;
(3) INCDMI Cantacuzino;
(4) Institute of Virology Stefan S. Nicolau
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5. Influence of probiotics upon the expresion of virulence and antibioresistance features
in strains isolated from gastroenterological infections
Delcaru Cristina (1), Podgoreanu Paulina (1), Alexandru Ionela (1), Violeta Corina Cristea
(2), Staiculescu Raluca-Madalina (2), Mariana Carmen Chifiriuc (3), Veronica Lazar (3),
Bleotu Coralia (4), Otilia Banu (5)
(1) Private Iancului Laboratory
(2) Department of Microbiology Reference Laboratory Central Synevo
(3) Faculty of Biology, University of Bucharest
(4) Institute of Virusology Stefan S. Nicolau
(5) Emergency Institute of Cardiovascular Diseases “Pro. Dr. C.C. Iliescu
6. Persistent effect of autologous bone marrow stem cell therapy on left ventricular
global longitudinal strain in patients with acute myocardial infarction and impaired left
ventricular function – a pilot study
Miruna Mihaela Micheu, Nicoleta Oprescu, Lucian Calmac, Daniela Pitic, Maria
Dorobantu
Department of Cardiology, Clinical Emergency Hospital of Bucharest
7. Difficulties in the etiological diagnosis of viral meningoencephalitis
C.P.Popescu (1,2), S. Ruta (2), S. Lazar(1,2), R. Rusu (1), M. Homos (1), V. Simion (1,2), M.
Nica (1,2), G. Tardei (1), S. Purice (1), A. Gutan (1), S. Florescu (1,2), E.Ceausu (1,2)
(1) Dr. Victor Babes Clinical Hospital of Infectious and Tropical Diseases, Bucharest
(2) Carol Davila University of Medicine and Pharmacy, Bucharest
8. Immunohistochemical assessment of basal cells in small glands pseudoneoplastic
lesions of the prostate
Manuela Enciu1,2, Mariana Aschie1,2, Anca Chisoi2, Gabriela Baltatescu 2, Sinziana- Andra
Ghitoi2
1)Department of Pathology, Faculty of Medicine, ‘’Ovidius’’ University, Constanta
2) Clinical Service of Pathology, Saint Apostle Andrew Emergency County Hospital,
Constanta
9. Morphometry and immunohistochemistry in testicular tumors diagnosis
Ionut Poinareanu 1,2, Mariana Aschie 1,2, Georgeta Camelia Cozaru 2, Anca Florentina
Mitroi 2,
Antonela Anca Nicolau 2, Oana Cojocaru 2
1)Pathology Department, Faculty of Medicine, “Ovidius” University Constanta
2)Pathology Reserch Team, Emmergency Clinical County Hospital Constanta
10. Clinicopathologicalstudy of KRAS-mutated andwild-type colorectal cancers
Mariana Așchie1,2, Georgeta Cozaru2, Anca Mitroi2, Gabriela Bălțătescu2, Ionuț
Poinăreanu1,2
1
Faculty of Medicine, „Ovidius” University Constanta (ROMÂNIA)
2
„Sf. Apostol Andrei” Constanta CountyEmergencyClinicalHospital (ROMÂNIA)
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11. Rolul major al analizei moleculare a mutatiilor genei k-ras in terapia anti-egfr
carcinomului colorectal
F. Cionca 1, G. Cardos 2
1.Institutul National de Cercetare-Dezvoltare in Domeniul Patologiei si Stiiintelor
Biomedicale “Victor Babes”, Bucuresti, Romania
2. Centrul de Genetica Medicala “Personal Genetics”, Bucuresti, Romania
12. Her 2 status in breast carcinomas determined by cish and ihc: comparation of the
results
Anca Mitroi1, Mariana Aşchie1,2, Georgeta Cozaru1, Gabriela Bălţătescu1, Ionuţ
Poinăreanu1,2, Anca Chisoi1, Manuela Enciu1,2, Anca Nicolau1, Oana Cojocaru1, Costel
Brînzan1
1 -Emergency Clinical County Hospital of Constanta, Pathology Department
2- “Ovidius” University of Constanta, Faculty of Medicine
13. HER2/Neu Amplification in Gastric Adenocarcinoma
Georgeta Camelia Cozaru1, Mariana Așchie1,2, Anca Mitroi1, Gabriela
Bălțătescu2,IonuțPoinăreanu1,2, Costel Brînzan1, Sînziana Ghițoi1
1
„Sf. Apostol Andrei” Constanta County Emergency Clinical Hospital (ROMÂNIA)
2
Faculty of Medicine, „Ovidius” University Constanta (ROMÂNIA)
14. Interleukina 22 in bolile inflamatorii intestinale
Alexandru Constantin Moldoveanu1, Mircea Diculescu2
1Clinica Gastreoenterologie si Medicina Interna II – SUUB, Universitatea de Medicina si
Farmacie „Carol Davila” Bucuresti
2Catedra de Gastroenterologie si Hepatologie Fundeni, Universitatea de Medicina si
Farmacie „Carol Davila” Bucuresti
15. Proteomic profiles of the intracystic papillary carcinoma of the breast
Gabriela Izabela Bălţătescu1), Mariana Aşchie1,2), Georgiana Cozaru1), Manuela Enciu1,2),
Ionut Poinăreanu1,2), Oana Cojocaru 1), Anca Chisoi 1), Sînziana Ghițoi1).
1)
Clinical Service of Pathology, Emergency County Hospital, Constanta, Romania
2)
Department of Pathology, Faculty of Medicine, “Ovidius” University, Constanta,
Romania
16. Proteomic analysis of laryngeal carcinomas
Oana Cojocaru1), Mariana Aşchie1,2), 1), Ionut Poinăreanu1,2), Anca Mitroi1), Anca Chisoi1),
Alexandra Maiorean1)
1)
Clinical Service of Pathology, Emergency County Hospital, Constanta, Romania
2)
Department of Pathology, Faculty of Medicine, “Ovidius” University, Constanta,
Romania
17. Enhanced green fluorescent protein (egfp) and coumarin labeling of hepatitis b virus
PAULA E. FLORIAN1, RAMONA N. GALANTONU2, CATALIN LAZAR2, SIMONA RUTA3, ANCA
ROSEANU1, NORICA NICHITA2
12
1
Institute of Biochemistry of the Romanian Academy, Ligand-Receptor Interactions
Institute of Biochemistry of the Romanian Academy, Viral Glycoproteins Dept.,
3
Stefan S. Nicolau Institute of Virology, Emergent Diseases Department
2
18. Cercetarea translaţíonală: o nouă frontieră pentru laboratoarele clinice
Alexandra Dana Maria Panait, Manole Cojocaru
“Titu Maiorescu” University, Faculty of Medicine, Bucharest
19. IN VITRO BIOLOGICAL SCREENING OF POTENTIAL ANALGESIC AND LOCAL ANAESTETIC
BENZANILIDES.
Mirela Serban1, Bianca Galateanu1,2, Diana Nuta3, Ariana Hudita1, Cornel Chirita3, Anca
Hermenean2, Aurel Ardelean2, Marieta Costache1
1
Department of Biochemistry and Molecular Biology, University of Bucharest, 91-95
SplaiulIndependentei, Bucharest 050095, Romania
2
Institute of Life Sciences, VasileGoldis Western University of Arad, 86 Rebreanu Street,
Arad 310414, Romania
3
Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila” of Bucharest,
6 TraianVuia Street, Bucharest, Romania
20. FETAL HYDROTHORAX: CASE REPORT - POSDRU/159/1.5/S/137390
Mihai DUMITRESCU, Dinu Florin ALBU, Crenguta ALBU
21. Aspecte imunohistochimice in neoplasmele colorectale - rezultate preliminare ale unui
studiu prospectiv
Mogoanta Stelian Stefanita1, MateescuOlivia Garofita2, Crafciuc Antoanela1,Streba
Liliana2, MogoantaLaurentiu2
UMF Craiova, Departamentul Chirurgie
UMF Craiova, Departamentul Histologie
22. ANTIGENGLYCOSYLATION AND CYTOTOXIC T CELLS ACTIVATION: CASE STUDY OF
TYROSINASE MUTANTS EXPRESSING HLA-A2 RESTRICTED YMD EPITOP
Gabriela N. Chiritoiu1, Cristian V.A. Munteanu1,Camilla Jandus2, Simona Ghenea1, Pedro
Romero2, Stefana M. Petrescu1
1
Institute of Biochemistry, Romanian Academy,2Ludwig Cancer Research Center, Faculty
of Biology and Medicine, University of Lausanne
23. Inflamatia cerebrala subclinica persistenta la pacienti infectati HIV
Diaconu Ioan Cristian
Prof. Dr. Matei Bals, National Institute of Infectious Diseases Bucharest, Romania
24. Expresia proteinelor S100 in cancerul pancreatic evidentiata prin nano-LC-MS/MS
Raluca M Boteanu1, Luminita Ivan1, Elena Uyy1, Viorel I Suica1, Florentina Safciuc1, Simona
Dima2, Irinel Popescu2,Maya Simionescu1, Felicia Antohe1 Raluca Florea (2), Veronica Ilie (2),
Andrei Sorop (2), Nicolae Bacalbasa (3), Valeria Tica (2)
13
1. Institutul de Biologie si Patologie Celulara “N. Simionescu”, Academia Româna,
Bucureşti, România
2. Institutul Clinic Fundeni, Bucureşti, România
25. Interactomics and live imaging as tools for identification and characterization of
endogenous factors involved in Hepatitis C Virus life cycle
Ovidiu Vlaicu1, Florin Pastrama1, Cristian Munteanu1, Georgiana Toma1, Simona
Paraschiv2, Dan Otelea2, Costin-Ioan Popescu1
1
Institute of Biochemistry of the Romanian Academy, Bucharest, Romania
2
National Institute of Infectious Disease „Matei Bals”, Bucharest, Romania
26. The pathway of degradation of hepatitis b virus (hbv) envelope proteins
Mihaela Uta, Catalin Lazar, Stefana Petrescu, Norica Nichita
Institute of biochemistry of the romanian academy
27. Prevalenta infectiilor digestive virale la copii in sezonul cald
Lazar S.**, Nica M.**, Nicoleta Tudor*, Obretin Dana*, Marcu Carmen* Rusu
Rodica*,Ceausu Em.**
* Spitalul de Boli Infectioase si Tropicale " Dr. V. Babes" Bucuresti
** UMF "Carol Davila" Bucuresti
28. IN VITRO biological screening of potential insulinmimetic metal-flavonoid complexes
Ariana Hudita1, Bianca Galateanu1, Alexandra Cristina Munteanu2, Valentina Uivarosi2,
Marieta Costache1
1
Department of Biochemistry and Molecular Biology, University of Bucharest, 91-95
SplaiulIndependentei, Bucharest 050095, Romania
2
Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila” of Bucharest,
6 TraianVuia Street, Bucharest, Romania
29. Uretrite sexual induse: panel etiologic
A. V. Dragodan1, F. Isopescu2, C. Giurcăneanu3
1
International Medical Center, Bucureşti,
2
Universitatea de Medicină şi Farmacie "Carol Davila“, Catedra de Obstetrică Ginecologie, Spitalul Clinic ”Nicolae Malaxa”, Bucureşti,
3
Universitatea de Medicină şi Farmacie "Carol Davila“- Catedra de Dermatologie
Oncologică şi Alergologie, Spitalul Universitar de Urgenţă “Elias”, Bucureşti
14