CT in NM Imaging Presented by: Donna Stevens, M.S. Senior Medical Physicist UT M. D. Anderson Cancer Center Houston, TX USA Part 2 CT Image Formation Objectives X-ray for CT imaging Back projection method of image reconstruction Effects of various reconstruction filters on the images Scan parameters affecting image quality Defining the concept of pitch in helical CT Slides are not to be reproduced without permission of author. CT Image Formation X-ray for CT imaging Image Reconstruction Image Quality Slides are not to be reproduced without permission of author. CT System Transmission imaging Narrow fan beam Rotate around patient Hundreds of projections Produce transaxial images Slides are not to be reproduced without permission of author. Computerized Axial Tomography One CT projection CT image from >700 Slides are not to be reproduced projections without permission of author. Axial Platforms first generation second generation third generation Slides are not to be reproduced without permission of author. Axial and Helical Platforms Slides are not to be reproduced without permission of author. Helical or Spiral CT Slip-ring gantry allows continuous rotation Reduction of interscan delays Constant table motion during scanning Special reconstruction methods developed Slides are not to be reproduced without permission of author. Pitch for Single-Slice CT Image and beam width are same for conventional CT Pitch = table travel ÷ beam width Typical pitch values are 0.7 to 2.0 Slides are not to be reproduced without permission of author. For Pitch < 1 Pitch Spirals overlap Dose is increased (at same mAs) For Pitch > 1 Spirals are stretched Dose is decreased (at same Slides mAs) are not to be reproduced without permission of author. Helical Interpolation Early helical used linear interpolation to estimate data for the “missing” projections Rebinning the collected data permits estimation of a data set 180° (opposite) from collected data Interpolation between the collected and “rebinned” projections reduces the scan length required to reconstruct each image Reduces the “helical” artifact Slides are not to be reproduced without permission of author. Helical Interpolation Collect data (black) Rebin to estimate the 180° data (red) Interpolate to estimate points between collected and rebinned data (blue) Helical CT needs fast computers Slides are not to be reproduced without permission of author. Beam Filtration Removes low energy x-rays from beam Low E photons contrib to dose, not image Filter reduces beam-hardening artifacts Shapes energy distribution across beam Removes more low energy from edges Results in more uniform beam hardening after passing through filter and patient Slides are not to be reproduced without permission of author. Beam Quality More filtration (“hard”) Avg energy higher Lower skin dose Better penetration Loss of contrast Less filtration (“soft”) Half-Value Layer kVp Mm Al needed to reduce exposure-in-air to one-half Typical HVL for x-ray: 2.5 to 5.0 mm Al Typical HVL for CT: 5.0 to 9.0 mm Al Slides are not to be reproduced without permission of author. Beam Hardening Light and dark variations in regions having high beam attenuation: Shoulders (apex of lungs) Skull Pelvis Low energy photons more readily absorbed Exit beam has higher average energy (is “harder”) Slides are not to be reproduced without permission of author. Beam Hardening Slides are not to be reproduced without permission of author. Beam Filtration X-ray fan beam Filter Shaped beam Patient More uniform output Pre-patient filter called “bowtie” Hardens and “shapes” beam for head or body imaging Slides are not to be reproduced without permission of author. Detector Characteristics X-ray absorption efficiency Response time Dynamic range High reproducibility Electronic stability and sampling rate Slides are not to be reproduced without permission of author. Solid State Detectors Photodiode multipliers (no PMT) CdWO4 crystals (old) 99% conversion and capture efficiency Ceramics (modern) 99% absorption, 3X conversion Slides are not to be reproduced without permission of author. Conventional CT Detectors Image width determined by beam thickness Pitch = table mm / beam mm Slides are not to be reproduced without permission of author. MSCT Detectors Single element – Image thickness determined by physical collimators Multiple element – Image thickness determined Slides are not to be reproduced electronically by withoutchannels permission of author. MSCT detectors 64 x 0.625 mm Table direction Slides are not to be reproduced without permission of author. Multi-Detector Concept Acquisition of multiple images per scan Electronic post-patient collimation Faster volume acquisition times Better bolus tracking and thin slices for 3D Slides are not to be reproduced without permission of author. Binning of Detector Elements 1 1.5 2.5 5.0 4-channel system Variable element, total 20mm 16-channel system 4 @ 1.5, 16 @ 0.75, 4 @ 1.5, total 24mm Slides are not to be reproduced without permission of author. 3rd Generation Platform Detector arc with ~1000 segments subdivided in zdirection Due to 8,000 to > 30,000 detector elements and assoc electronics, 4th gen MSCT platform not feasible Slides are not to be reproduced without permission of author. CT Image Formation X-ray for CT imaging Image Reconstruction Image Quality Slides are not to be reproduced without permission of author. CT Image Reconstruction Detector signal represents attenuation by all material along a path µ value (attenuation coefficient) calculated for each path Infinite number of paths needed for perfect reproduction of object Realistic limitations on number of paths Sampling rate of electronics Dose to patient Heat loading on system Slides are not to be reproduced without permission of author. Reconstruction Filters 1 Object 2 Projection data 3 Recon filter 1 2 3 4 4 Backprojection of filtered data 5 Backprojection of filtered data for two angles 5 Slides are not to be reproduced without permission of author. Filtered Backprojection Filtered profile Slides are not to be reproduced without permission of author. Filtered Backprojection Slides are not to be reproduced without permission of author. Ideal “Standard” “Edge” Various filters produce different effects in the structure of the noise. Slides are not to be reproduced without permission of author. Effects of Recon Filters on Resolution Std Recon Soft Recon Slides are not to be reproduced without permission of author. Effects of Recon Filters on Resolution Std Recon Bone Recon Slides are not to be reproduced without permission of author. Effects of Recon Filters on Resolution Std Recon Detail Recon Slides are not to be reproduced without permission of author. Effects of Recon Filters on Resolution Std Recon Edge Recon Slides are not to be reproduced without permission of author. Effects of Recon Filters on Noise Recon Filter Soft Standard Lung Detail Bone Edge Bone Plus Std Dev Water Img 3.8 4.7 19.6 6.5 18.8 35.8 27.0 Slides are not to be reproduced without permission of author. Reconstruction “Filters” “Standard” recon filter “Bone” recon filter Slides are not to be reproduced without permission of author. Dx vs Attenuation CT Standard recon Attenuation correction recon Slides are not to be reproduced without permission of author. Pitch Pitch = table travel ÷ beam width Typical pitch values are 0.7 to 2.0 For Pitch < 1 For Pitch > 1 Spirals overlap Spirals are stretched Dose is increased (at same mAs) Dose is decreased (at same mAs) Slides are not to be reproduced without permission of author. Helical Interpolation Collect data (black) Rebin to estimate the 180° data (red) Interpolate to estimate points between collected and rebinned data (blue) Helical CT needs fast computers Slides are not to be reproduced without permission of author. MSCT Image Recon Axial system uses 360° data for each image Conventional helical uses < 360° data, depending on pitch, then interpolates MSCT uses small arcs (<90°) from each element, plus interpolation, to “build” 360° of data Slides are not to be reproduced without permission of author. MSCT Pitch Pitch = table travel ÷ beam width Beam width due to pre-patient collimators not image width • Pitch relates to dose Beam width and effective mAs Slides are not to be reproduced without permission of author. MSCT Image Recon Image 1 Table direction A D B C Lesion moves from Channel A to D in one rotation Slides are not to be reproduced without permission of author. MSCT Image Reconstruction To get Image 1 Sample Channel A for 1st qtr rotation Channel B for 2nd qtr rotation Channel C for 3rd qtr rotation Channel D for 4th qtr rotation Apply all that data to Image 1 Slides are not to be reproduced without permission of author. 4-channel Recon, Pitch = 1.0 Image 5 Image 1 A D B C Table direction Qtr A arc 1st Im1 2nd 3rd 4th 5th B C D Slides are not to be reproduced without permission of author. 4-channel Recon, Pitch = 1.0 Image 5 Image 1 A D B C Table direction Qtr arc 1st 2nd 3rd 4th 5th A B C D Im1 Im2 Im1 Slides are not to be reproduced without permission of author. 4-channel Recon, Pitch = 1.0 Image 5 Image 1 A D B C Table direction Qtr arc 1st 2nd 3rd 4th 5th A B C D Im1 Im2 Im1 Im3 Im2 Im1 Slides are not to be reproduced without permission of author. 4-channel Recon, Pitch = 1.0 Image 5 Image 1 A D B C Table direction Qtr arc 1st 2nd 3rd 4th 5th A B C D Im1 Im2 Im1 Im3 Im2 Im1 Im4 Im3 Im2 Im1 Slides are not to be reproduced without permission of author. 4-channel Recon, Pitch = 1.0 Image 5 A Image 1 D B C Table direction Qtr arc 1st 2nd 3rd 4th 5th A B C D Im1 Im2 Im1 Im3 Im2 Im1 Im4 Im3 Im2 Im1 Im5 Im4 Im3 Im2 Slides are not to be reproduced without permission of author. CT Image Formation X-ray for CT imaging Image Reconstruction Image Quality Slides are not to be reproduced without permission of author. Image Quality Parameters kVp pitch mA effective mAs Rotation time recon filters mAs image thickness focal spot size display field size Slides are not to be reproduced without permission of author. Effective mAs To compare protocols, need effective mAs Eff mAs = mA • time ÷ pitch To compare if kVp’s are different Correct effective mAs by kVp2 eff mAsold • (kVpnew2 / kVpold2) then compare to eff mAsnew Slides are not to be reproduced without permission of author. Comparing Protocols w/ Eff. mAs Scanner 4-slice Image 7.5 Detector 4 x 3.75 Pitch 0.75 kVp 120 mA 200 Rotation 0.8 Eff. mAs 213 8-slice 7.5 8 x 2.5 .625 120 200 0.8 16-slice 7.5 16 x 1.25 1.375 120 320 0.5 256 116 Slides are not to be reproduced without permission of author. What it does When to change kVp contrast, penetration very lg or very sm patient mAs # x-rays “noise” in image display FOV image spatial resolution patient body size Parameter Slides are not to be reproduced without permission of author. Parameter What it does When to change image thickness resolution, noise reformats fine structure recon filters smooth, edge enhance depends on reason for study focal spot size spatial resolution user cannot control Slides are not to be reproduced without permission of author. Summary Detectors Binning for multi-row Pitch Filtered back projection Image Quality Parameters Effective mAs Slides are not to be reproduced without permission of author. Thank You! Slides are not to be reproduced without permission of author.