David J. Zelner - McHale & Slavin, P.A.

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David J. Zelner’s practice at McHale | Slavin focuses on patent prosecution, and
advising clients on patent portfolio strategies. Mr. Zelner has an advanced degree
in cell biology in addition to a law degree and specializes in biotechnology.
Prior to pursing his legal degree, Mr. Zelner spent over seven years in the research
laboratories at Northwestern University Medical School, Chicago, Illinois, in the
Department of Urology developing technical experience in a variety of cellular and
molecular biology related technologies. In support of multiple NIH-funded projects,
Mr. Zelner conducted research developing novel prostate cancer treatment
strategies and identifying prostate cancer markers, including the development of
advanced prostate cancer screening tools. Mr. Zelner also performed research
examining the role of TGF-β in prostate cancer and the use of this growth factor as
a target for gene therapy and immunotherapy. Additionally, Mr. Zelner conducted
research in the area of molecular mechanisms of neuropathic erectile dysfunction
and the neural control of prostate development and function.
David J. Zelner
Registered Patent Attorney
email
User, H., Zelner, D.J., McKenna, K.E., McVary, K.T. Microarray analysis and
description of SMR1 gene in rat penis in a post-radical prostatectomy model of
erectile dysfunction. J Urol. 170(1):298-301, 2003.
User, H.M., Hairston, J.C., Zelner, D.J., McKenna, K.E., and McVary, K.T. Penile
Weight and Cell Subtype Specific Changes in a Post-Radical Prostatectomy
Model of Erectile Dysfunction. Journal of Urology, 169, 1175-1179, March 2003.
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Telephone: 561.625.6575
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Scientific Publications:
Podlasek, C.A., Zelner, D.J., Tang, Y., McKenna, K.E., McVary, K.T. Altered
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Telephone: 561.625.6575
Facsimile: 561.625.6572
Education:
University of Texas, Austin, B.A. Biology 1992
DePaul University College of Law, J.D. 2004
(Certificate in Intellectual Property: Patents)
DePaul University, M.S., Cell Biology/Biology
2005
Admissions:
Florida Bar
Illinois Bar
United States Supreme Court
United States Court of Appeals for the Federal
Circuit
United States District Court for the Southern
District of Florida
United States District Court for the Northern
District of Illinois
United States Patent & Trademark Office
Professional Affiliations:
American Bar Association
American Intellectual Property Law Association
Chicago Bar Association
BioFlorida
Sonic hedgehog signaling is associated with profound morphological abnormalities
in the penis of the BB/WOR diabetic rat, Biol. Reprod. 69(3):816-27, 2003.
Podlasek, Carol A., Zelner, David J., Jiang, Hong Bin, Houston, John, McKenna,
Kevin E., McVary, Kevin T. Sonic Hedgehog cascade is required for penile
postnatal morphogenesis, differentiation, and adult homeostasis. Bio Repro. 68:
423-438, 2002.
Podlasek, C.A., Gonzalez, C.M., Zelner, D.J., Jiang, H.B., McKenna, K.E.,
McVary, K.T. Highlight Article: Analysis of NOS isoform changes in a post radical
prostatectomy model of erectile dysfunction. J of Urology, May 2002.
Podlasek, C.A., Gonzalez, C.M., Zelner, D.J., Jiang, H.B., McKenna, K.E.,
McVary, K.T. Analysis of NOS isoform changes in a post radical prostatectomy
model of erectile dysfunction. International Journal of Impotence Research. 13
Suppl. 5, S1-S5, 2001.
Podlasek, C.A, Zelner, D.J, Bervig T.R., Gonzalez, C.M., McKenna K.E., McVary
K.T. Characterization and localization of NOS isoforms in BB/WOR diabetic rats. J
Urology. 166: 746-755, 2001.
Gonzalez, C.M., Brannigan, R.E., Zelner, D.J., Bervig, T., Podlasek, C.A.,
McKenna, K.E., McVary, K.T. Protein and gene expression of nitric oxide
synthase isoforms I and II in the rat penile shaft. J Andrology. 22(1):54-61, 2001.
Kindu, Shilajit D., Kim, Isaac Y., Zelner, David J., Janulis, Lynn, Goodwin,
Shannon, and Lee, Chung. Loss of expression of transforming growth factor-ß type
II receptor is associated with an aggressive growth pattern in a renal carcinoma
cell line, Renca. J Urology. 160(5):1883-9, 1998.
Rohlff, C., Blagosklonny, M. V., Kyle, E., Kesari., A., Kim. I.Y., Zelner, D, Hakim,
F., Trepel, J., Bergan, R.C. Prostate cancer cell growth inhibition by tamoxifen is
associated with inhibition of protein kinase c and induction of p21wafl/cip l.
Prostate. 37:51-59, 1998.
Nemeth, J.A., Zelner, D.J., Lang, S, Lee, C. Keratinocyte growth factor in the rat
ventral prostate: androgen-independent expression. J. of Endo.156:115-125, 1998.
Kim, Isaac, Zelner, David, and Lee, Chung. The conventional transforming growth
factor ß (TGF-ß) receptor type I, is not required for TGFß1 signaling in a human
prostate cancer cell line, LNCaP. Exp. Cell Res. 241:151-160, 1998.
Nemeth, Jeffrey A., Sensibar Julia A., White, Roxanne R., Zelner, David J., Kim,
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Isaac Y., and Lee, Chung. The prostatic ductal system in rats: Tissue-specific
expression and regional variation in stromal distribution of transforming growth
factor ß1. Prostate 33:64-71, 1997.
Qian, Yi, Sensibar, Julia, Zelner, David J., Schaeffer, Anthony J., Judith A., Finlay,
Rittenhouse, Harry G., and Lee, Chung. Two-dimensional gel electrophoresis
detects prostate-specific antigen-∂1-antichymotrypsin complex in serum but not in
prostatic fluid. Clinical Chemistry 43(2): 352-359, 1997.
Kim, Isaac, Ahn, Han-Jong, Zelner, David J., Shaw, Jennifer E., Lang, Sharon,
Kato, Mitsuyasu, Oefelein, Michael, Miyazono, Kohei, Nemeth, Jeffrey A.,
Kozlowski, James M., and Lee, Chung. Loss of expression of transforming growth
factor ß receptors type I and II correlates with tumor grade in human prostate
cancer tissues. Clinical Cancer Research 2: 1255-1261, 1996.
Kim, Isaac Y., Kim, Jin-Ho, Zelner, David, Ahn, Han-Jong, Sensibar, Julia A., and
Lee, Chung. Transforming growth factor ß1 is a mediator of androgen-regulated
growth arrest in an androgen-responsive prostatic cancer cell line, LNCaP.
Endocrinology 137:991-999, 1996.
Kim, Isaac Y., Ahn, Han-Jong, Zelner, David J., Shaw, Jennifer W., Sensibar, Julia
A, Kim, Jin-Ho, Kato, Mitsuyasu, and Lee, Chung. Genetic change in transforming
growth factor ß (TGF-ß) receptor type I gene correlates with insensitivity to TGFß1 in human prostate cancer cells. Cancer Research 56:44-48, 1996.
Kim, Isaac Y., Zelner, David J., Sensibar, Julia A, Ahn, Han-Jong, Park, Linda,
Kim, Jin-Ho, and Lee, Chung. Modulation of sensitivity to transforming growth
factor-ß ( TGF-ß) and the level of type II TGF-ß receptor in LNCaP cells by
dihydrotestosterone. Experimental Cell Research. 222:103-110, 1996.
Kim, Isaac Y., Ahn, Han-Jong, Zelner, David J., Park, Linda, Sensibar, Julia A,
and Lee, Chung. Expression and localization of transforming growth factor-ß
receptors type I and type II in the rat ventral prostate during regression. Molecular
Endocrinology 10: 107-115, 1996.
Lee, Chung, Sutkowski, Debra M., Sensibar, Julia A, Zelner, David, Kim, Isaac,
Amsel, Irma, Shaw, Norman, Prins, Gail S., and Kozlowski, James. Regulation of
proliferation and production of prostate specific antigen in androgen-sensitive
prostate cancer cell line, LNCaP, by dihydrotestosterone. Endocrinology 136:
6796-803, 1995.
Scientific Presentations:
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"Analysis of Directed Extracellular Fluorescent Bead Movements Over the Surface
of Diatoms." Presentation & defense of research for Master of Science degree,
2005.
"Bilateral cavernous nerve resection caused a compensatory increase in NOS III
expression in the penis," co-presented at 2nd Fall Meeting Society for the Study
of Impotence, September 15-17, 2000, Cleveland, OH
"Distribution of NOS expression in normal and diseased tissues," co-presented at
1st Fall Meeting Society for the Study of Impotence, October 1-3, 1999, Boston,
MA
"Detection of prostate-specific antigen-∂1-antichymotrypsin complex in serum but
not in prostatic fluid or seminal fluid,” co-presented at the 90th Annual Meeting of
the American Urological Association, April 23-28, 1995, Las Vegas, NV
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