Best practice in MI care 2009 One-day meeting for health care professionals Royal College of Physicians Regent’s Park, London Chair: Professor Martin R. Cowie Delegate Booklet 17 June 2009 Accredited by Royal College of Physicians (5 hours) and Royal College of Nursing (6 hours) Supported by Pfizer Ltd 1 Chairman’s introduction 09 Professor Martin R. Cowie SURVIVAL AFTER MYOCARDIAL infarction (MI) has improved markedly in recent years, largely due to faster reperfusion treatment and better prescribing of evidence-based secondary prevention treatment. However, many challenges remain regarding the optimum care of all patients with MI. The purpose of today’s conference is to provide an update on the achievements to date and to highlight where service improvement is still needed and how this might be achieved. We have a distinguished panel of speakers whose presentations will cover treatment of acute MI pre-hospital and in-hospital and the appropriate continuing care after discharge. In terms of emergency treatment of MI, the conference is timely given the Department of Health’s recent recommendation of primary percutaneous coronary intervention (PCI) as the main treatment for STelevation MI in England, with pre-hospital thrombolysis encouraged where primary PCI is not possible.1 We will hear about the opportunities and logistic challenges of primary PCI services, UK guidelines on MI care, and strategies for minimising delay between symptom onset and reperfusion, which is central to improved outcome. Another key issue to be discussed is heart failure, which often develops in the context of MI. Left ventricular dysfunction must be identified promptly so that early treatment can be initiated, as this has been shown to influence outcome. Specialist nurses have an important role in helping to screen MI patients for heart failure, particularly when patients are not being treated on a cardiology ward. We will also hear how the recent changes in acute MI care – as well as pressures to limit length of hospital stay – impact on work in district general hospitals and what systems can be put in place to optimise patient care in response to these changes. A further presentation will highlight cur- Professor Martin R. Cowie Professor of Cardiology, Imperial College London and Honorary Consultant Cardiologist, Royal Brompton Hospital, London rent deficiencies in care for elderly patients with MI. These patients still tend to miss out on the improvements in MI care that have been achieved in other groups. One major point that is likely to be emphasised by today’s speakers is the importance of collaborative multidisciplinary working between primary and secondary care as a key component of best practice in MI care. The conference is accredited for Continuing Professional Development by the Royal College of Physicians and the Royal College of Nursing. It is intended to be an interactive meeting and there will be plenty opportunity for questions. Please do not hold back from contributing to the discussion sessions. Reference 1. Treatment of heart attack national guidance: final report of the National Infarct Angioplasty Project (NIAP). Department of Health, 2008. 2 | Best practice in MI care 2009 Faculty Dr Huon Gray Deputy National Director for Heart Disease and Stroke, Department of Health (England), and Consultant Cardiologist, Southampton University Hospital E-mail: huon@cardiology.co.uk Dr Clive Weston Reader in Clinical Medicine, Swansea University, and Honorary Consultant Cardiologist, ABM University Trust E-mail: c.f.m.weston@swansea.ac.uk Dr Iain Findlay Consultant Cardiologist, Greater Glasgow and Clyde Health Board E-mail: findli@aol.com Professor Adam Timmis Professor of Clinical Cardiology, London Chest Hospital E-mail: adamtimmis@mac.com Professor Martin R. Cowie Professor of Cardiology, Imperial College London and Honorary Consultant Cardiologist, Royal Brompton Hospital, London E-mail: m.cowie@imperial.ac.uk Professor Richard Hobbs Professor and Head of Primary Care Clinical Sciences, University of Birmingham E-mail: f.d.r.hobbs@bham.ac.uk Dr Jackie Taylor Consultant Physician, Department of Medicine for the Elderly, Glasgow Royal Infirmary E-mail: jackie.taylor@ggc.scot.nhs.uk Bernie Downey Cardiac Nurse Specialist, Mater Hospital Site, Belfast Health and Social Care Trust E-mail: bernie.downey@belfasttrust.hscni.net Dr Tim Gray Consultant Cardiologist, Pennine Acute Hospitals NHS Trust E-mail: tim.gray@pat.nhs.uk 3 Programme 9.30 Welcome and introduction Professor Martin R. Cowie The big picture 9.45 MI care: National progress and challenges Page 4 Dr Huon Gray 10.15 MINAP: Painting the picture Page 5 Dr Clive Weston 10.45 UK guidelines: NICE and SIGN Page 6 Dr Iain Findlay 11.15 Panel Discussion 11.30 Coffee Key areas 12.00 Minimising the delay to reperfusion Page 7 Professor Adam Timmis 12.20 Heart failure – detection and treatment Page 8 Professor Martin R. Cowie 12.40 Hand-over to primary care: Don’t drop the ball Page 9 Professor Richard Hobbs 1.00 Panel discussion 1.30 Lunch Time for action 2.30 Don’t forget the many – issues for the elderly Page 10 Dr Jackie Taylor 2.50 Joining up care: Evolving role of the nurse in MI care Page 11 Bernie Downey 3.10 How to make it happen in real life Dr Tim Gray 3.30 Panel discussion 4.00 Summary and close Page 12 4 | Best practice in MI care 2009 MI care: National progress and challenges Notes: 09 Dr Huon Gray DR HUON GRAY trained in cardiology at the Brompton and St George’s Hospitals, London, and was appointed Consultant Cardiologist at Southampton University Hospital in 1989. He has been Honorary Secretary of the British Cardiovascular Intervention Society, President of the British Cardiovascular Society, and cochaired the UK National Infarct Angioplasty Project (NIAP). Dr Gray is currently clinical adviser to NICE on acute coronary syndromes and Deputy National Director for Heart Disease and Stroke at the Department of Health (England). He chairs the International Council of the American College of Cardiology. THE MANAGEMENT OF patients with myocardial infarction, both ST elevation (STEMI) and non-ST elevation (NSTEMI), has been transformed over the last 25 years, from conditions often associated with an inhospital mortality of over 20% in the early 1980s to a current day average mortality approaching 5%. These acute coronary syndromes are all part of a single spectrum and the factors associated with the dramatic improvement in outcome owe much to the success of intervening at different pathophysiological points in their development. These interventions include the use of pharmacotherapy (such as antithrombins and antiplatelet agents), the uptake of earlier coronary angiography and appropriate coronary revascularisation, greatly increased use of secondary prevention intervention, and thrombolytic agents and primary PCI for the management of patients with STEMI. The mortality from cardiovascular diseases has been falling for many years but there is a risk of complacency unless we remind ourselves that cardiovascular diseases are still the number one cause of death worldwide and carry with them an associated high morbidity. With the alarming rate of increase in obesity and diabetes there is a risk of these positive trends being reversed. This talk will present an overview of these developments, the importance of data collection and analysis, some of the Department of Health policy initiatives that have encouraged change,1-4 and a brief summary of the challenges still to be overcome. References 1. National Service Framework for Coronary Heart Disease. Department of Health, 2000. http://www.dh.gov.uk/en/Publicationsands tatistics/Lettersandcirculars/Healthservice circulars/DH_4004813 2. The Coronary Heart Disease National Service Framework: Building on excellence, maintaining progress. Progress Report for 2008. Department of Health, 2009. http://www.dh.gov.uk/en/Publicationsands tatistics/Publications/PublicationsPolicyA ndGuidance/DH_096555 3. Treatment of heart attack national guidance: final report of the National Infarct Angioplasty Project (NIAP). Department of Health, 2008. http://www.dh.gov.uk/en/Publicationsands tatistics/Publications/PublicationsPolicyA ndGuidance/DH_089455 4. High quality care for all: NHS Next Stage Review final report. Department of Health; 2008. http://www.dh.gov.uk/en/Publicationsands tatistics/Publications/PublicationsPolicyA ndGuidance/DH_085825 5 MINAP: Painting the picture Notes: 09 Dr Clive Weston DR CLIVE WESTON is Reader in Clinical Medicine at the School of Medicine, Swansea University, and Honorary Consultant Cardiologist at ABM University Trust. He is also Chair of the Steering Group of the Myocardial Ischaemia National Audit Project (MINAP) within the National Institute for Clinical Outcomes Research, University College London. THE MYOCARDIAL ISCHAEMIA National Audit Project (MINAP) collects data from all English and Welsh hospitals with responsibility for the management of patients with acute coronary syndromes. Although the data are not exhaustive, and the emphasis, until recently, has been the care of those presenting with ST-segment elevation, analysis of the dataset allows important audit of hospi- tal (and pre-hospital) management against a limited number of agreed standards of care. This forms part of the public assurance of the quality of care provided by the health service as well as being a useful tool for healthcare workers and health service commissioners. Additionally, analysis gives an insight into the types of patient presenting with heart attack, improvements in particular aspects of care within individual hospitals and changes in patterns of care across regions and nationally. Observational studies using the dataset generate interesting hypotheses for later testing. In my talk I will introduce the concept of national registries and national audit and present a mix of data as examples of the utility of MINAP. 6 | Best practice in MI care 2009 UK guidelines: NICE and SIGN Notes: 09 Dr Iain Findlay DR IAIN FINDLAY is a Consultant Cardiologist with Greater Glasgow and Clyde Health Board. He was chair of the SIGN Acute Coronary Syndromes guideline group and is currently chair of the NHS Quality Improvement Scotland (NHSQIS) Audit and Indicators Steering Group. Dr Findlay’s principal clinical interest is in inherited cardiac conditions. He is lead clinician for the West of Scotland Regional Inherited Cardiac Conditions. THE NATIONAL INSTITUTE for Health and Clinical Excellence (NICE) and the Scottish Intercollegiate Guidelines Network (SIGN) differ in the manner by which topics are selected, in the evaluation of the evidence, with regard to economic analysis and cost implication, but hopefully not on their recommendations for patients. SIGN 931 specifically addressed the topic of acute coronary syndromes, starting in 2005. The guideline members decided to look at ACS under the following headings: z Presentation, assessment and diagnosis z Management in the first 12 hours z Reperfusion therapy for ST-elevation acute coronary syndromes z Risk stratification and non-invasive testing z Invasive investigation and revascularisation z Early pharmacological intervention z Treatment of hypoxia and cardiogenic shock z Patient support and information needs. It is important to emphasise that a SIGN guideline need not be a full review of a subject. Within ACS we looked at 24 specific areas of interest to the group. The release of new evidence during the guideline review period was a problem and while it clarified issues such as the place of primary percutaneous intervention (PCI), in other areas such as antithrombotic therapy for non-ST elevation myocardial infarction (NSTEMI) this was not the case. Areas that gave us particular concerns were the definition of myocardial infarction and its implications for patients and for epidemiologists. The most appropriate use of troponins was the subject of much debate. Our recommendations on the duration of clopidogrel following NSTEMI gave us the most feedback and was one area where we differed from published NICE guidance. The interventionalists were overwhelming in their support for primary PCI and this led to the most radical change in the management of myocardial infarction in Scotland since the introduction of thrombolysis, leading to major changes in the delivery of care for acute MI. Reference 1. SIGN. Acute Coronary Syndromes. National Clinical Guideline 93; 2007. 7 Minimising the delay to reperfusion Notes: 09 Professor Adam Timmis PROFESSOR ADAM TIMMIS is Professor of Clinical Cardiology at the London Chest Hospital. He qualified from the University of Cambridge and St Bartholomew’s Hospital Medical College in 1973. His cardiology training was at Massachusetts General Hospital, Boston, US, and at Guy’s Hospital, London, where he was Senior Registrar before taking up his current post. Professor Timmis has published extensively in the cardiovascular literature, his major interests being angina and acute coronary syndromes. He is Editor of Heart and chair of the Academic Group of the Myocardial Ischaemia National Audit Project (MINAP). IN ACUTE MYOCARDIAL infarction, most deaths occur early after symptom onset, often before the patient has gained access to medical care. These deaths are usually caused by ventricular fibrillation and are therefore preventable once a suitably equipped ambulance is to hand or the patient has been delivered to hospital. Once in hospital, death is usually caused by heart failure, largely dependent on the severity of myocardial injury which can be reduced by timely reperfusion therapy. The risk of primary ventricular fibrillation declines exponentially following onset of symptoms and after 6-12 hours is very low. The benefits of reperfusion therapy exhibit a similar time course, being maximal immediately after coronary occlusion and declining over the next 12 hours. Thus the most important means of saving lives in acute myocardial infarction is to get the patient to a defibrillator and to initiate antithrombotic and reperfusion therapy as soon as possible after the onset of symptoms. Three major components contribute to treatment delays in suspected myocardial infarction: z Patient delay: time from pain onset to the summoning of help z Transport delay: time from the summoning of help to arrival at hospital z Treatment delay: time from arrival at hospital to delivery of reperfusion therapy. The third component (“door-toneedle/balloon time”) has proved the most amenable to modification, although evidence is now emerging that current targets are overly modest and further efforts are needed to deliver treatment more quickly. It is the first two components, however, that most delay the delivery of treatment. Patient delay is the major factor but, even when the decision has been made to seek medical help, many patients fail to call an ambulance, choosing instead less efficient methods of accessing medical care. This talk will discuss those factors that are associated with delayed treatment of myocardial infarction and will attempt to quantify how additional lives might be saved by reducing treatment delay. There is a lot more to be done if further reductions in mortality from acute myocardial infarction are to be achieved. 8 | Best practice in MI care 2009 Heart failure – detection and treatment Notes: 09 Professor Martin R. Cowie PROFESSOR MARTIN R. COWIE is Professor of Cardiology, Imperial College London and Honorary Consultant Cardiologist, Royal Brompton Hospital, London. Professor Cowie has a longstanding clinical and research interest in heart failure diagnosis and management. He was Chair of the British Society for Heart Failure from 2007 to 2009, and acted as the clinical expert for the NICE guideline on chronic heart failure, published in 2003. He advised the Healthcare Commission on its recent national audit of heart failure. Since 2007, Professor Cowie has chaired the Education Committee of the Heart Failure Association of the European Society of Cardiology, and sits on its Board. MUCH OF THE improvement in standards of care for heart failure in the UK has arisen from professional guidelines for chronic heart failure (such as from NICE, SIGN and the European Society of Cardiology) coupled with a workforce targeted on implementing good practice for such patients. There has been little focus, however, on acute heart failure such as that occurring in the context of acute myocardial infarction (MI). Despite improvements in the treatment of ST elevation MI, with more rapid thrombolysis or access to primary percutaneous intervention, up to 20% of patients still suffer from significant left ventricular damage and/or heart failure peri-infarction. Even transient signs of heart failure are associated with a worse prognosis, and heart failure is now the leading cause of death in both the short and medium term after MI. Detection of significant left ventricular damage post-infarction should not be difficult, with a key role for echocardiography in addition to good clinical examination. Neglected groups include the elderly, those with diabetes, and those with non-ST elevation infarction. “MI detectives” have been used to good effect at some hospitals – these are heart failure nurse specialists who systematically screen new patients admitted to hospital with a troponin rise to identify those with left ventricular damage or heart failure. What is more difficult is to ensure that such patients are considered for appropriate drug therapy and monitoring over the days and weeks after their infarction. This requires good communication between different services in hospital and in the community, and a sense of ownership of the process by a local champion. Rehabilitation services, chronic heart failure services, the coronary care unit, and primary care all have a role to play. Too many patients still do not gain the full benefits of modern therapy with appropriate doses of renin-angiotensin system blockers, beta-blockers and eplerenone, titrated upwards in the early period after infarction when the ventricle is likely to be remodelling and the risk of arrhythmia and progressive heart failure is at its highest. 9 Hand-over to primary care: Don’t drop the ball Notes: 09 Professor Richard Hobbs PROFESSOR RICHARD HOBBS is Professor and Head of Primary Care Clinical Sciences at the University of Birmingham. He is co-Director of the Quality and Outcomes (QOF) Review Panel and Deputy Director of the NIHR National School for Primary Care Research. He sits on the Board of the British Primary Care Cardiovascular Society. He currently Chairs the Council for Cardiovascular Primary Care, European Society of Cardiology; the Prevention and Care Board, British Heart Foundation; and the European Primary Care Cardiovascular Society. Professor Hobbs’ research interests focus on cardiovascular epidemiology and trials, especially relating to vascular and stroke risk, and heart failure. He consulted on the National Service Framework for coronary heart disease and several NICE reviews. He has provided clinical care in inner-city general practice for more than 25 years. FOR SURVIVORS OF myocardial infarction (MI) and acute coronary syndrome, guidelines advise clinicians on priorities for ongoing preventative and treatment goals. For example, the NICE guideline on secondary prevention after MI (guideline 48) recognises the importance of treating dyslipidaemia, hypertension and smoking as the main risk factors for cardiovascular disease, plus additional preventive therapies including antiplatelet and beta-blocker therapy. Despite the availability of highly effective medication, numerous studies show that at-risk patients often fail to reach the treatment goals recommended in the guidelines. The prevalence of poorly controlled hypertension is still high. Lipid targets are easier to achieve than blood pressure targets; however, the EUROASPIRE II study1 of 5,556 patients hospitalised with coronary artery disease revealed that only 61% received statin treatment after discharge, and only 51% of these had total cholesterol levels below goal. A similarly low incidence of eli- gible patients attaining lipid treatment goals was found in the US L-TAP study.2 There are governmental, physician and patient factors that can either detract from or improve implementation of guidelines. Lack of awareness and understanding of cardiovascular disease and cholesterol management among the general public may contribute to this treatment gap. Adherence with prescribed drug therapy is especially important in patients at high risk for cardiovascular disease, ie, those with co-morbid hypertension and dyslipidaemia. Several medication factors have been shown to play a role in influencing patient adherence to therapy, especially adverse effects of medication, number of medications (lower pill burden is associated with better adherence with antihypertensive and lipid-lowering therapy), order of medications (initiating antihypertensive treatment and lipid-lowering treatment concomitantly is associated with better adherence), and combination treatment. Physician issues, especially in primary care, include variable under-treatment and under-titration of therapy. Government endorsement of guidelines via national health policy may help to reduce the burden of cardiovascular disease and to change physician and patient behaviour. Financial incentives for reaching specific clinical indicators in the Quality and Outcomes Framework have made a large impact. References 1. Lifestyle and risk factor management and use of drug therapies in coronary patients from 15 countries; principal results from EUROASPIRE II Euro Heart Survey Programme. Eur Heart J 2001;22:554-72. 2. Pearson TA, Laurora I, Chu H, Kafonek S. The lipid treatment assessment project (LTAP): a multicenter survey to evaluate the percentages of dyslipidemic patients receiving lipid-lowering therapy and achieving low-density lipoprotein cholesterol goals. Arch Intern Med 2000;160:459-67. 10 | Best practice in MI care 2009 Don’t forget the many – issues for the elderly Notes: 09 Dr Jackie Taylor DR JACKIE TAYLOR is a Consultant Physician in the Department of Medicine for the Elderly, Glasgow Royal Infirmary. After graduating from Glasgow University and a period of general professional training, she became Lecturer in the University Department of Geriatric Medicine and then jointly accredited in General Internal and Geriatric Medicine. Dr Taylor represents Geriatric Medicine on the Steering Group of the Cardiac Managed Clinical Network and chairs the Heart Failure Subgroup. From a clinical perspective, her main interest is the development of comprehensive multidisciplinary services for heart failure patients, and she has developed a Heart Failure Clinic and Day Hospital programme specifically tailored to the needs of older people. She is Honorary Secretary of the Royal College of Physicians and Surgeons of Glasgow. THE INCIDENCE OF myocardial infarction (MI) rises steeply with age: the over 75 age group currently comprises 8% of the population, but accounts for one-third of all MIs and 60% of all MI deaths. The changing demography of our population will result in a growing number of older individuals at risk of MI. While there have been considerable advances in the management of MI overall, these have not resulted in tangible benefits for many older patients. There are many potential factors that may explain this phenomenon. Older patients are more likely to present atypically and to present late.1 They more frequently have non-ST elevation MI, and complex co-morbidity including other manifestations of vascular disease such as cere- brovascular disease and cognitive dysfunction result in lower use of invasive strategies. Older patients are at high risk of developing heart failure post MI: age and presence of heart failure are the strongest predictors of one-year mortality,2 but older patients are less likely to have an assessment of left ventricular function. Prescription of evidenced-based therapies is consistently lower in older patients post MI3 and although there is growing evidence of the benefit of cardiac rehabilitation in this age group, both referral and uptake are relatively poor. There is no magic bullet to resolve these problems; indeed, some factors are not modifiable. What can be influenced is the model of care to promote systematic identification of patients, appropriate management of coronary artery disease and other co-morbidity, multidisciplinary working and good communication. References 1. Rich MW. Epidemiology, clinical features, and prognosis of acute myocardial infarction in the elderly. Am J Geriatr Cardiol 2006;15:7-11. 2. Montalescot G, Dallongeville J, Van Belle E, et al. STEMI and NSTEMI: are they so different? 1 year outcomes as defined by the ESC/ACC definition (the OPERA registry). Eur Heart J 2007;28:1409-17. 3. Myocardial Ischaemia National Audit Project (MINAP) data 2008. 11 Joining up care: Evolving role of the nurse in MI care Notes: 09 Bernie Downey BERNIE DOWNEY is a Cardiac Nurse Specialist at the Belfast Health and Social Care Trust, with responsibility for leading and co-ordinating the cardiac rehabilitation service at the Mater site. She is an independent nurse prescriber and runs a nurse-led clinic for secondary prevention for post-MI patients. She is past President of the British Association for Cardiac Rehabilitation (BACR). During her time as President she was responsible for the publication of standards and core components of cardiac rehabilitation. She has an active interest in the care of heart failure patients and has for many years promoted their inclusion in streamline cardiac rehabilitation services. Ms Downey is an honorary lecturer at Queen’s University Belfast. FOR A PATIENT who has had a myocardial infarction (MI), admission to the coronary care unit (CCU) should ensure immediate contact with cardiac rehabilitation (CR) and heart failure services. Specialist nurses working within these areas ensure ongoing assessment, investigation and optimisation of treatment. They have a positive impact on a patient’s care by improving compliance and ensuring decision-making is evidence based. They are often the focal point for stimulating multi-professional care. However, CCU beds are not always available and MI patients can be admitted to other wards where they are managed by a non-cardiologist. This not only can result in different treatment strategies being put into place but also compromises the onward referral to specialist nurses involved in CR services. CR has been shown to reduce mortality1 and should be offered to all patients who have had an MI.2 The patient’s journey following an MI can be complex. Primary percutaneous coronary intervention, day case angiography and “treat and return” have resulted in shorter hospital stays with the patient being more likely to transfer between different hospitals on the same admission. Within the same hospital, the patient can be placed in several different care environments, which can complicate continuity of care. The experienced CR nurse is ideally placed to screen for heart failure after MI. The nurse can also influence prescribing decisions and identify the need for investigations or follow-up of results. As a key player in the team the nurse can ensure the “joining up” of the infarct with the heart failure. Protocols to ensure all post-MI patients are referred to CR services will result in assessment by the nurse no matter where the patient is placed and, if appropriate, onward referral to heart failure or other services. Referral to CR services from care of the eld- erly and medical wards remains poor and needs to be improved. CR and heart failure services both work on the interface between secondary and primary care and ensure a more structured patient follow-up, often with protocols common to both areas. CR can, if properly resourced, provide the necessary vehicle to allow nurses to drive forward the organisation of care required by the patient with an MI complicated with heart failure. References 1. Taylor RS, Brown A, Ebrahim S, et al. Exercise-based rehabilitation for patients with coronary heart disease: Systematic review and meta-analysis of randomized controlled trials. Am J Med 2004;116:682-92. 2. NICE. Secondary prevention in primary and secondary care for patients following a myocardial infarction. Clinical guideline 48; 2007. 12 | Best practice in MI care 2009 How to make it happen in real life Notes: 09 Dr Tim Gray DR TIM GRAY graduated from St John’s College, Cambridge University and completed his basic medical training in Southampton. He then spent two years in Papworth Hospital performing research into chronic angina before moving to the North West of England to complete his cardiology training. He was appointed Consultant Cardiologist for the Pennine Acute Hospitals NHS Trust, based at The Royal Oldham Hospital, in May 2007. Dr Gray is trained in all aspects of interventional cardiology which he carries out at Rochdale Infirmary and Manchester Royal Infirmary. He looks after patients with all aspects of general cardiology in both inpatient and outpatient settings, but his interests lie particularly in patients with acute coronary syndrome and the medical and interventional treatments of this. CARING FOR PATIENTS with myocardial infarction (MI) remains challenging in real world practice. Although the number of ST elevation MIs appears to be falling, the evolution to primary angioplasty means that many of these patients present to their local hospital having already had an angioplasty at their regional “heart attack centre.” With an emphasis on getting these patients home more quickly, district general cardiologists often find themselves trying to initiate and titrate vital medications, arrange important investigations like echocardiography, and start the process of cardiac rehabilitation in everreducing time frames. Add to this the enor- mous rise in patients who are now being diagnosed with non-ST elevation MI since the introduction of troponin testing, and there are increasing pressures on our coronary care units. This talk will describe the processes in place to tackle these issues, as well as how we monitor our performance. Published by Logos Healthcare Communications Ltd (www.logoscommunications.co.uk) Supported by Pfizer Ltd