GAMBARAN BIAYA DAN EFEKTIVITAS ANTIBIOTIK PASIEN RAWAT INAP Community Acquired Pneumonia (CAP) SEBELUM DAN SETELAH PENERAPAN JAMINAN KESEHATAN NASIONAL DI RSUP DR. SARDJITO YOGYAKARTA INTISARI Pneumonia adalah peradangan yang menyerang parenkim paru, ditandai dengan reaksi inflamasi berupa alveolitis dan penggumpalan eksudat yang dapat ditimbulkan oleh bakteri. Antibiotik adalah terapi utama pada pneumonia. Penggunaan antibiotik yang tidak tepat menimbulkan resistensi sehingga perawatan pasien menjadi lebih lama, biaya pengobatan lebih mahal, dan penurunan kualitas pelayanan kesehatan. Jaminan Kesehatan Nasional melalui Badan Penyelenggara Jaminan Sosial merupakan sistem asuransi kesehatan yang bertujuan agar masyarakat dapat memenuhi kebutuhan dasar kesehatan yang layak. Tujuan penelitian ini adalah untuk mengetahui pola penggunaan antibiotik, gambaran biaya antibiotik dan efektivitas antibiotik pada pasien rawat inap CAP sebelum dan setelah penerapan JKN di RSUP Dr. Sardjito Yogyakarta. Penelitian ini merupakan penelitian deskriptif dengan rancangan cross sectional. Data diambil secara retrospektif dari catatan rekam medik dan Unit Teknologi Informasi RSUP dr. Sardjito Yogyakarta. Subyek penelitian ini adalah pasien rawat inap Januari 2013-Juli 2014 dengan 30 pasien yang memenuhi kriteria inklusi. Gambaran biaya dilihat berdasarkan antibiotik yang digunakan pasien selama di rawat inap. Efektivitas antibiotik dinilai dengan membandingkan hasil laboratorium awal dan akhir dari White Blood Cell dan neutrofil, jika mengalami penurunan maka terapi efektif. Hasil penelitian ini menunjukkan pola penggunaan antibiotik dan efektivitas antibiotik sebelum dan setelah penerapan JKN tidak jauh berbeda. Pola penggunaan antibiotik terbanyak yaitu seftriakson dan azitromisin, dengan efektivitas antibiotik 95% pada pasien pre-JKN dan 100% pada pasien JKN. Rata-rata biaya antibiotik pada pasien pre-JKN Rp. 267.137 dan JKN Rp. 568.830,3. Persentase biaya penggunaan antibiotik dibandingkan biaya keseluruhan obat pada pasien pre-JKN adalah sebesar 2,87% dan pada pasien JKN adalah 5,51%. Kata kunci: Gambaran biaya antibiotik, CAP, Efektivitas antibiotik, RSUP Dr. Sardjito Yogyakarta xiv THE REPRESENTATION OF THE ANTIBIOTICS COST AND THE EFFECTIVENESS OF ANTIBIOTICS IN UNDERGOING THE HOSPITALIZATION PATIENTS Community Acquired Pneumonia (CAP) BEFORE AND AFTER THE IMPLEMENTATION OF THE NATIONAL HEALTH INSURANCE IN DR. SARDJITO HOSPITAL YOGYAKARTA ABSTRACT Pneumonia is inflammation which attacks the lungs parenchyma, characterized by an inflammatory reaction in the form of alveolitis and exudates clotting that can be caused by bacteria. Antibiotic is the main therapy of pneumonia. The improper use of antibiotic which can cause resistance that the treatment to the patient becomes longer, the cost of treatment becomes more expensive, and ultimately it causes the declining quality of health care. National Health Insurance through Social Security Institution is a health insurance system which has purpose for the people in order to fulfill the proper basic need of health. The purpose of this study is to know the pattern of antibiotic using, the representation of the antibiotics cost, and the effectiveness of antibiotic in undergoing the hospitalization patients of pneumonia before and during the applying National Health Insurance in dr. Sardjito Hospital Yogyakarta. This study is a descriptive study using the cross sectional. The data are obtained retrospectively from medical record and Department of Information Technology Unit in dr. Sardjito Hospital Yogyakarta. The subject of this study is the undergoing hospitalization patients in January 2013 to July 2014 with 30 patients who appropriate the inclusive criteria. The representation cost is seen based on the antibiotic which is used by patient during the hospitalization. The effectiveness of antibiotic is valued by comparing the first and last laboratory’s result form White Blood Cell and neutrophils, if they are decreasing so the therapy is effective. The result of this study indicates that the pattern of antibiotic using and the effectiveness of antibiotic before and during applying National Health Insurance is not that different. The highest pattern of antibiotic using are ceftriaxone and azithromycin, with 95% antibiotic effectiveness to the patients before National Health Insurance and 100% to the patient during National Health Insurance. The average cost of antibiotics in patients preJKN Rp. 267.137 and JKN Rp. 568.830,3. The cost percentage of antibiotic using that compares with the cost of all medicines to patient before National Health Insurance is 2,87% and to the patient during National Health Insurance is 5,51%. Keywords: The representation of the antibiotics cost, community of pneumonia, the effectiveness of the antibiotics, Dr. Sardjito Hospital Yogyakarta xv