The 2 for 1 special: Not always a good deal The 2 for 1 special . . . Johanne Delisle, r.t CHU Sainte-Justine Medical imaging department Montreal, Quebec, Canada Not always a good deal The 2 for 1 special . . . Refered patient, gestation period of 24 weeks: ? ? ? type of twin pregnancy ? ? ? Polyhydramnios The 2 for 1 special . . . Oligohydramnios The 2 for 1 special . . . Hydrops Stuck twin 1 Quiz question The 2 for 1 special . . . How many varieties of twin pregnancies are there? 2, 3, 4, 5, 6 The 2 for 1 special . . . The 2 for 1 special . . . 6 Types 6 Types 1. DIZYGOTIC dichorionic – diamniotic (DI – DI) 2. MONOZYGOTIC dichorionic – diamniotic 3. MONOZYGOTIC monochorionic – diamniotic 5. Conjoined twins (pathological division ) 6. Acardius (pathological division ) (DI – DI) (MONO – DI) 4. MONOZYGOTIC monochorionic – monoamniotic (MONO – MONO) The 2 for 1 special . . . Conjoined twins Incomplet and late division Conjoined areas and shared organs The 2 for 1 special . . . Acardius Absence of heart The « normal » twin provides blood flow through placental anastomoses 2 The 2 for 1 special . . . Popular belief Mortality – Morbidity Non-identical or dizygotic Identical or monozygotic DZ Dichorionic – Diamniotic 9% MZ Monochorionic – Diamniotic MZ : 26% Monochorionic – Monoamniotic MZ : 50% The 2 for 1 special . . . → → → 2 ovules 66% of cases familial history → → → 1 ovule 33% of cases « genetic mistake" Dizygotic twins The real scientific data . . . DIchorionic (2 placentas) Always DIamniotic Dizygotic twins DIchorionic Dizygotic twins DI - DI DIZYGOTIC DIamniotic DI - DI 3 1. Dizygotic twins Dizygotic twins DI - DI DI - DI Fetal genders ? 1. Fetal genders ? 2. 2 placentas 1. Dizygotic twins Dizygotic twins DI - DI DI - DI Fetal genders ? 2. 2 placentas 3. Thick membrane Dizygotic twins DI - DI 100 % 1. Different fetal genders Quiz question Could these twins be DI – DI? 2. 2 placentas 4 Dizygotic twins Dizygotic twins YES 2 fused placentas 2 fused placentas Dizygotic twins Dizygotic twins DI - DI DI - DI 2 placentas 100% 3. Thick membrane > 2 mm + 2 layers single placenta Dizygotic twins DI - DI 3. Thick membrane Twin Peak Sign or Lambda sign reliable Dizygotic twins What is the optimal timing gestation to recognize the DI – DI? 8 weeks 14 weeks 18 weeks 26 weeks 5 Dizygotic twins Dizygotic twins Dichorionic twins 8 weeks Monochorionic twins Late assessment = Twinning type mistakes Dizygotic twins Quiz question 2 placentas 1 thick membrane 2 males The first trimester is the most reliable time to characterize the type of twinning Monozygotic twins YES Monozygotic twins present as DI – DI in 30% of cases The parents ask you if the twins can be «identical » ? Monozygotic twins MONOchorionic (1 placenta) MONOZYGOTIC DIamniotic MONO - DI 6 Monozygotic twins Monozygotic twins MZ Mono - Di MZ Mono - Di Monozygotic twins MONO - DI Monozygotic twins MONO - DI 1. Same fetal gender (100%) Monozygotic twins MONO - DI Monozygotic twins MONO - DI 1. Same fetal gender (100%) 1. Same fetal gender (100%) 2. Single placenta 2. Single placenta 3. Thin membrane (100%) (100%) 7 Monozygotic twins 3. Thin membrane Monozygotic twins MONOchorionic Monozygotic twins Membrane thin thick Monozygotic twins MZ Mono - Mono (single placenta) MONOZYGOTIC MONOamniotic MONO - MONO MZ twins Monozygotic twins MONO - MONO Monozygotic Mono - Mono 8 Monozygotic twins Monozygotic twins MONO - MONO MONO - MONO 1. Same fetal gender (100%) 1. Same fetal gender (100%) 2. Single placenta Monozygotic twins MONO - MONO (100%) Monozygotic twins 3. No membrane 1. Same fetal gender (100%) 2. Single placenta 3. No membrane (100%) Monozygotic twins Monozygotic twins Cords Mono-Mono Entanglement Strangulation 9 The 2 for 1 special . . . The 2 for 1 special . . . Monochorionic US follow-up for normal twin pregnancies: Complication = Vascular anastomoses Twin-to-twin transfusion syndrome (TTS) Twin embolisation syndrome (TES) Complications (I) ¾ Preterm labor Premature rupture of membranes - monochorionic > dichorionic ¾ Fetal malformations - monochorionic > dichorionic ¾ Weight discrepancy (ratio > 0.93) Amniotic fluid discrepancy - monochorionic = dichorionic Quiz question What type of twins ? ? ? Dz DI-DI Mz DI-DI Mz MONO-DI Mz MONO-MONO Early exam Every 2 weeks from 18 24 weeks Every 4 weeks (MZ-DZ) Complications (II) ¾ Intrauterine demise - monochorionic > dichorionic ¾ Twin to twin transfusion syndrome (TTS) - monochorionic ¾ Twin embolisation syndrome (TES) - monochorionic ¾ Cord entanglement - monochorionic - monoamniotic Quiz question Type of twinning DZ DI-DI 10 Acknowledgements Acknowledgements Andree Grignon M.D. Suzanne Laframboise Jocelyne Gagne Laurent Garel M.D. 11