Peripheral Nervous System PNS consists of nerves that branch out from the CNS and connect to other body parts. • Somatic (outer; voluntary) nerves that connect CNS to skin and skeletal muscles for conscious movement and sensory input. • Autonomic (visceral; involuntary) – connect CNS to visceral organs (heart, stomach, intestines, other glands) for unconscious activities. Receptors • External receptors (exteroceptors) – Sensitive to stimuli outside the body. Found at or near body surface (e.g. touch, pressure, pain). • Internal receptors (interoceptors) – Receive stimuli arising from internal viscera (e.g. GI tract, bladder, lungs). • Proprioreceptors – Measures the degree of stretch of locomotor organs, sending positional information to the CNS. Components • Nerves – most are mixed nerves with both sensory and motor fibers. – Cranial nerves (12 pair) attached to brain – Spinal nerves (31 pair) attached to the spinal cord. • Ganglia – Aggregation of nerve cell bodies Cranial Nerves • • • 12 pair, numbered I-XII from rostral (superior) to caudal (inferior). First 2 from forebrain, the rest from the brain stem. All serve the neck and head, except the vagus (thoracic and abdomen). Cranial nerves S=sensor M=motor B=both(mixed) I II III IV V Name Olfactory Optic Oculomotor Trochlear Trigeminal S,M, or B S S M M B VI Abducent VII Facial M B VIII Vestibulocochlear IX Glossopharyngeal S B X Vagus B XI Accessory M XII Hypoglossal M Function smell vision eye muscles eye muscles S- face & scalp M- muscles of mastication eye muscles S- tongue & taste M- facial muscles hearing & equilibrium S- tongue & taste General sensation of pharynx M- pharyngeal muscles(swallowing) S- visceral sensation M- visceral movement swallowing, head & shoulder movement tongue- speech & swallowing Extra credit – 5 pts., you come up with an original saying. If you and a friend work on it together and it is too similar…….. I II III IV V Name Olfactory Optic Oculomotor Trochlear Trigeminal On Old Olympos’ Towering Top VI Abducent VII Facial A Fin VIII Vestibulocochlear IX Glossopharyngeal And (V?) German X Vagus Viewed XI Accessory A XII Hypoglossal Hop S=sensor M=motor B=both(mixed) Spinal Nerves • 31 pairs, each exits spinal cord between vertebrae (except C1 which is above), inferior to vertebra of same number. • Mixed nerves (sensory and motor) that provide two way communications between spinal cord and arms, legs and trunk. Spinal Nerves • Mixed – motor and sensory – Afferent – carry sensory info to spinal cord (CNS) from receptors. – Efferent – carry motor info out to effector organs • Somatic – skeletal muscles • ANS – smooth muscle, glands Roots and Branches • Each nerve emerges by 2 short roots in spinal column. – Dorsal (sensory) – note dorsal root ganglion contains cell bodies of sensory neurons which conduct impulses inward from peripheral body. – Ventral (motor) – consists of axons from motor neurons whose cell bodies are located in gray matter of spinal cord. • Roots unite to form spinal nerve proper which passes through intervertebral formamen and the splits into branches. • Spinal nerve splits just lateral to intervertebral foramen. • Dorsal ramus (posterior branch); nerve turns posteriorly and innervates muscles and skin of back. • Ventral ramus (anterior branch); main portion continues anteriorly to supply muscles and skin on front and sides of trunk and limbs. • Rami communicantes (communicating rami of ANS) – Serves sympathetic motor nerves. • Rami communicantes consist of preganglionic, postganglionic and sensory axons. The ANS always displays two neurons in the motor pathway from CNS to the effector organ. - This contrasts with the situation in the somatic-efferent system where there is one neuron in the path from CNS to a skeletal muscle effector. The two ANS neurons are designated the pre- and post-ganglionic neurons. Nervous System Afferent Division (sensory division) Efferent Division (motor division) Autonomic Sympathetic “Stress” Somatic Parasympathetic “Calm” 1. Preganglionic (pre-g) neurons and their axons (fibers) - Cell body located in the CNS, originates in lateral horn. - its axon may reach most, or only part, of the distance to target organ it projects to through ventral root, - and synapses on, the postganglionic neuron in chain ganglia 2. Postganglionic (post-g) neurons and fibers - the cell body is located in an autonomic ganglion (motor ganglion) - its axon may be relatively short, or long - it projects to, and synapses on, a visceral effector organ • Rami communicantes (communicating rami of ANS) – Rami communicantes consist of preganglionic, postganglionic and sensory axons. • White rami communicantes consist of the many myelinated pre-g fibers leaving their spinal nerve. Gray rami communicantes consists of many non-myelinated post-g fibers returning to each mixed spinal nerve. Reflex Arc Five essential components: 1) receptor, 2) afferent neuron, 3) interneuron, 4) efferent neuron and 5) effector organ. Plexuses • Ventral rami of spinal nerves combine to form complex networks called plexuses. Plexuses • Each terminal branch of plexus contains fibers from several different spinal nerves • Each muscle in a limb receives nerve fibers from more than one spinal nerve. Innervation of Skin • Dermatomes - each pair of spinal nerves supplies a particular area of body skin. • Dermatome map help localize sites of injury to dorsal roots (sensory) of the spinal cord. Autonomic Nervous System And Visceral Sensory Neurons ANS consists of motor neurons that serve: • Cardiac muscle • Smooth muscle – Viscera – respiratory, digestive, excretory and genital organs – Blood vessels • Glands – Adrenal gland Comparison of Somatic Motor Nerves and ANS Motor Nerves Somatic vs. ANS 1. Voluntary control Involuntary control 2. Innervates skeletal muscle Innervates cardiac and smooth muscle, and glands 2 neurons (pre and post synaptic) ½ myelinated: presynaptic thinly myelinated post synaptic nonmyelinated 3. One neuron (CNS to skeletal muscle) 4. Myelinated Sympathetic vs. Parasympathetic • The 2 ANS divisions generally act as antagonists, one will activate, the other inhibit most organs. • Sympathetic (norepinephrine) speeds up heart. • Parasympathetic (acetylcholine) will slow it down. • Both systems are usually operating with one exerting more influence depending upon the situation. Parasympathetic Division • Preserves normal resting functions. Protects and preserves resources. Most active under ordinary, restful (calm) conditions. • Postganglionic membrane secretes acetylcholine. • Terminal ganglia are located near visceral organ (not in chain ganglia), so postganglionic fibers are short. Craniosacral Out Flow • Cranial Parasympathetic Outflow – Innervates head, neck , thorax, most of abdomen • Sacral Parasympathetic Outflow – Innervates abdomen (distal colon) and pelvic organs (bladder, reproductive organs) Sympathetic Division • More extensive than parasympathetic system. Supplies visceral organs and superficial ‘visceral’ structures (sweat glands, arrector pili muscles, smooth muscles of blood vessels). • Stress division. • Postganglionic fibers secrete norepinephrine. • Terminal ganglia near spinal cord, post-g long. • Axons branch profusely. Thoracolumbar Outflow • Spinal nerve outflow • Sympathetic trunk (sympathetic chain), formed by paired ganglia • Preganglionic cell bodies lie in lateral horn of spinal gray matter. Other ganglia are nearer to the effector organ.