DACTARI
Lead
Physico-chemical properties
DACTARI
Element
Symbol
Atomic number
Atomic weight
Chemical series
Discovered
Origin of the name
Electron configuration
Density
Melting point
Boiling point
Pearson classification (acid and base)
Electronegativity (Pauling scale)
Ionic Radius (Marcus)
Coordination number
Oxidation states (main in bold)
Redox potential
Main mineral compounds (solids)
Main Industrial compounds (solids)
Main industrial compounds (solution)
Main isotopes
Lead
Pb
82
207.2
Poor transition metals
Known since ancient time
From Latin plumbum, name for soft metals
[Xe] 4f14 5d10 6s2 6p2
10.66 g/cm3
327°C
1749°C
Soft
2.33
1.18 A
4-8
2+
2 (Pb ), 4 (Pb4+)
- 0.126 V (Pb/Pb2+), 1.80 (Pb2+/Pb4+)
Galena (PbS), cerussite (PbCO3), anglesite
(PbSO4)…
PbO, PbO2, Pb2O3, PbS, PbCl2, PbCl4, PbSO4…
Pb-tetraethyl:(CH3CH2)4Pb (liquid)
PbCl2, PbNO3, PbSO4 , Pb(CH3CO2)2…
210Pb (T = 22.3 y, , γ) (1g = 2.83 1012 Bq)
1/2
DACTARI
Lead
Acute toxicity
DACTARI
Element
Symbol
Lead
Pb
LD 50 (mg/kg) (rat/oral)
Lead (all soluble inorganic compounds)
Lead oxide : PbO
Lead chloride : PbCl2
Lead nitrate : Pb(NO3)2
Lead sulfate : PbSO4
Lead acetate : Pb(CH3CO2)2
Lead (organic compounds)
Lead tetraethyl
Lead tetramethyl
LDLO 190 – 20500 (dog, GP)
LDLO 1300 (dog)
LDLO 1490 (Guinea Pig)
LDLO 313 (Guinea Pig)
LDLO 1370 (dog) – 20500 (GP)
LDLO 191 (dog)
1.2 - 105
1.2 – 12.3
105
References
Fractionnal absorption : fA (ICRP 100)
Materno-fœtal transfer (ICRP 88)
Classification
LD50*
2 - NC
3
3
3
3 - NC
2
1-2
1
2
ATSDR, INCHEM, HSDB
0.2 – 0.6
1
*Classification of Acute Toxicity on the Basis of the LD 50.
Very Toxic (1)
Oral (mg/kg)
Inhalation
(mg/l/4h)
Dermal
(mg/kg)
25
0.25 for
aerosols or
particulates
Toxic (2)
R28
>25-200
R25
>200-2000
R26
>0.25-1 for
aerosols or
particulates
>0.5-2 for gases
or vapours
R23
>1-5 for
aerosols or
particulates
>2-20 for gases
or vapours
R20
R27
>50-400
R24
>400-2000
R21
0.5 for gases
or vapours
50
Harmful (3)
R22
Non Classified
(NC)
>2000
>5 for aerosols
or particulates
>20 for gases or
vapours
>2000
This table is based on the COMMISSION DIRECTIVE 2001/59/EC of 6 August 2001 adapting to technical progress for the
28th time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating
to the classification, packaging and labelling of dangerous substances.
DACTARI
Lead
Chronic toxicity
DACTARI
Element
Symbol
WHO
RN water guide value (Bq/L)
chemical water guide value (mg/L)
CMR classification
IARC (1 to 4)
Isotopes
210Pb
0.1
CEE
-
EPA
Non carcinogen
Critical effect
RfD (reference dose) mg/kg/d
NOAEL mg/kg/d
Risk phrases
Risk group (Delacroix)
# Specific activity : 210Pb (1g = 2.83 1012 Bq)
IARC carcinogenicity to humans:
-
C:1
C : 2A
C : 2B
C:3
C:4
Carcinogenic to humans
Probably carcinogenic to humans
Possibly carcinogenic to humans
Unclassifiable as to carcinogenicity for humans
Probably not carcinogenic for humans
Radiotoxic groups (Delacroix et al., 2002) :
G 1 : Exemption < 104 Bq
G 2 : Exemption < 105 Bq
G 3 : Exemption = 106 Bq
G 4 : Exemption = 107 Bq
G 5 : Exemption > 108 Bq
Lead
Pb
Chemical compound
0.01
Lead inorganic C : 2B
Lead organic C : 3
Hydrogenoarsenate lead C : 1
Inorganic lead C : 3
Organic-inorganic R : 1
Lead inorganic B : 2
Target organs : bone, kidneys, brain
Pb-acetate : 0.9 - 27
61-62-40-48-22
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