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364

S 230A-D
Thursday, May 08, 2014 8:30 AM-10:30 AM
Anatomy/Pathology / Clinical/Epidemiologic
Research / Cornea / Glaucoma /
Multidisciplinary Ophthalmic Imaging /
Physiology/Pharmacology / Retinal Cell Biology /
Retina
Hall SB
Thursday, May 08, 2014 8:30 AM-10:30 AM
Biochemistry/Molecular Biology / Clinical/
Epidemiologic Research / Genetics / Physiology/
Pharmacology / Retinal Cell Biology / Retina /
Visual Neuroscience
Abnormal ocular circulation is associated with the leading causes of blindness: macular degeneration, diabetic retinopathy, and glaucoma. Recent technological advances have greatly enhanced the ability to image and measure ocular circulation.
This session will address basic principles, emerging technologies, and their application to clinical practice.
AMD has an increasingly well-defined genetic basis. Potent genetic risk alleles have been identified by genome-wide association studies that are beginning to implicate specific biological processes in the pathogenesis of AMD. In this symposium we will explore how studies based on discovery of specific genetic risk alleles (i.e. Tyr402His in CFH) are revealing potential mechanism of disease in
AMD.
Moderators: Yoshiaki Yasuno, Gilbert T. Feke,
Susumu Ishida and Juan E. Grunwald
5414 — 8:30 Quantification of ocular blood flow.
Leopold Schmetterer.
1 Clinical Pharmacology,
2
Medical University of Vienna, Vienna, Austria;
Center of Medical Physics and Biomedical
Engineering, Medical University of Vienna, Vienna,
Austria
5415 — 8:45 Optical coherence tomography angiography.
Yali Jia. Oregon Health & Science
University, Portland, OR *CR
5416 — 9:00 Autoregulation of ocular circulation in glaucoma.
Alon Harris .
Ophthalmology, Indiana University , Indianapolis ,
IN *CR
5417 — 9:15 Death of choriocapillaris in agerelated macular degeneration.
Gerard A.
Lutty.
Wilmer Eye Inst , Baltimore, MD
5418 — 9:30 Ocular blood flow in diabetic retinopathy.
Taiji Nagaoka. Ophthalmology,
Asahikawa Medical University, Asahikawa, Japan
5419 — 9:45 Angiogenesis in corneal diseases.
Claus Cursiefen. Dept of Ophthalmology,
University of Cologne, Koln, Germany *CR
5420 — 10:00 Remodelling of Retinal Vessels in Arterial Hypertension Measured by Adaptive
Optics.
Georg Michelson. Ophthalmology,
Erlangen, Germany
— 10:15 Panel Discussion
Moderators: Margaret M. DeAngelis, Caroline C.
Klaver and Steven J. Fliesler
5421 — 8:30 Overview of the current state of
AMD genetics.
J ohanna Seddon. Ophthalmology,
Tufts University School of Medicine, Boston,
MA *CR
5422 — 8:50 Links between ARMS2 genotype, gene expression, and potential roles in AMD.
Gaofeng Wang. Hassman Institute for
Human Genomics, University of Miami, Miami, FL
5423 — 9:10 The influence of CFH genotype and age-related changes in Bruch’s membrane on AMD pathogenesis.
Anthony J. Day. Faculty of Life Sciences , The University of Manchester,
Manchester, United Kingdom
5424 — 9:30 Future directions in AMD
Genetics.
Michael Gorin.
1 Dept of Ophthalmology,
Jules Stein Eye Institute - UCLA, Los Angeles,
CA; 2 Human Genetics, David Geffen School of
Medicine - UCLA, Los Angeles, CA *CR
5425 — 9:50 CFH genotype and choroidal vascular disease in AMD.
Robert
Mullins . 1 Ophthalmology and Visual Sciences,
University of Iowa, Iowa City, IA; 2 The Stephen A
Wynn Institute for Vision Research, Iowa City, IA
5426 — 10:10 Exploring the role of complement in AMD via opportunistic clinical scenarios.
Andrew Lotery.
United Kingdom; 2
1 Ophthalmology - Eye
Unit, Southampton General Hospital, Southampton,
Kingdom *CR
Clinical Neurosciences,
University of Southampton, Southampton, United
Thursday – Symposium – 5414 – 5426 f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
365

Thursday Posters 8:30 am – 10:15 am
5427 – 5447– Thursday – Posters
Exhibit/Poster Hall SA A0001-A0020
Thursday, May 08, 2014 8:30 AM-10:15 AM
Anatomy/Pathology
Moderators: Jacob Pe’er and Rebecca C. Stacy
5427 — A0001 Childhood Orbital, Ocular and
Optic nerve tumors in Egypt.
Ahmad S.
AlFaar 1, 2 ,
M. S. Bakry
Children Cancer Hospital - Egypt 57357, Cairo,
Egypt; 2
1 , S. Ezzat 1, 3 . 1 Research Department,
Ophthalmology, Cairo University School of Medicine, Cairo, Egypt; 3 Public Health, National
Liver Institute, Shebin Elkom, Egypt
5428 — A0002 Successful management of ocular juvenile xanthogranuloma using off-label bevacizumab: a report of 2 cases.
Noy Ashkenazy,
C. M. Henry, A. Abbey, C. A. McKeown, A. M.
Berrocal, T. G. Murray. Bascom Palmer Eye
Institute, Miami, FL
5429 — A0003 Giant Orbital Hydrocystoma in Children: Report of Three Cases.
Mehrdad
Malihi 1 , R. Turbin 1 , N. Mirani 2 , P. D. Langer 1 .
1 The
Institute of Ophthalmology and Visual
Sciences, New Jersey Medical School, Newark,
NJ; 2 Department of Pathology, New Jersey Medical
School, Newark, NJ
5430 — A0004 Growth rates of orbital cavernous hemangiomas: A quantitative analysis.
Liza M.
Cohen
A. Karagianis 2 . 1
1 , A. Jayaram 1 , G. Lissner 1
Ophthalmology, Northwestern
University, Chicago, IL; 2 Radiology, Northwestern
University, Chicago, IL
,
5431 — A0005 Clinicopathologic Correlation of Caruncular Lesions.
Sander R. Dubovy 1, 2 , A. J.
1, 2 Bermudez 1, 2 , J. Thompson .
1 Bascom Palmer Eye
Institute, University of Miami, Miami, FL; 2 FLorida
Lions Ocular Pathology Laboratory, Miami, FL
5432 — A0006 Immunohistochemical Analysis of Sebaceous Cell Carcinoma in Comparison to Both Basal Cell Carcinoma and Squamous
Cell Carcinoma.
Andre N. Ali-Ridha 1, 2
Brownstein 1, 2 , K. Jiang 1, 2 , T. Milman 3
, S.
, B. Burns 2
Blanco 2 , J. Farmer 2 .
1
University of Ottawa, The Ottawa Hospital, The
Ottawa Hospital Research Institute, Ottawa, ON,
, P.
Department of Ophthalmology,
Canada; 2 Department of Pathology and Laboratory
Medicine, University of Ottawa, The Ottawa
Hospital, Ottawa, ON, Canada;
Ear Infirmary, New York, NY
3 Departments of
Ophthalmology and Pathology, New York Eye and
5433 — A0007 Sebaceous gland carcinoma of the ocular adnexa - variability in histological and immunhistochemical appearance.
Eva J.
Becker 1, 2 , M. C. Herwig 1, 2 , F. G. Holz 1
K. U. Loeffler 1, 2 . 1 Ophthalmology, University
Eye Hospital Bonn, Bonn, Germany; 2
, H. Fischer 3
Ophthalmic
Pathology, University Eye Hospital Bonn, Bonn,
Germany; 3 Pathology, University Bonn, Bonn,
Germany
,
5434 — A0008 Molecular Profiling of Ocular
Surface Squamous Neoplasia Identifies Multiple
DNA Copy Number Alterations Including
Recurring 8p11.22 Amplicons.
Saeed AlWadani 1, 3 ,
L. Asnaghi 1 , H. Alkatan 2
Edward 1, 2
Arabia; 3
, C. Eberhart 1 .
1
, H. Al -Hussain 2 , D.
Ophthalmic Pathology,
Johns Hopkins Hospital, Baltimore, MD; 2
Ophthalmology, King Saud University,
Riyadh, Saudi Arabia *CR
King
Khaled Eye Specialist Hospital, Riyadh, Saudi
5435 — A0009 Establishment and characterization of squamous cell carcinoma cells from the human bulbar conjunctiva.
Bettina
Mueller, H.
Thomasen , K.
Steuhl , D.
Meller .
University Duisburg Essen, Essen, German y
5436 — A0010 Intraoperative High Dose Rate
32P Brachytherapy for Diffuse Conjunctival
Neoplasms.
Brian Marr 1
Cohen 3 , C. Barker 2 . 1
, D. H. Abramson
Kettering, New York, NY; 2
1
Memorial Sloan Kettering, New York, NY;
, G.
Surgery, Memorial Sloan radiation oncology,
3 Medical
Physics, Memorial Sloan Kettering, New York, NY
5437 — A0011 A heterotopic model for tumorassociated (lymph)angiogenesis in the murine cornea - feasibility of intrastromal tumor cell injections.
Konrad R.
Koch , N.
Refaian, D.
Hos, M.
Matthaei , F.
Bock , S.
L.
Schlereth, M.
Becker , C.
Cursiefen, L.
M.
Heindl . Department of
Ophthalmology, University of Cologne, Cologne,
German y
5438 — A0012 New mouse model for conjunctival melanoma.
Simona L. Schlereth 1
, L. M. Heindl 1 .
1
, C.
Department of
,
S. Iden 2 , M. Mescher
Cursiefen 1
2 , K. R. Koch 1
Ophthalmology, University of Cologne, Cologne,
Germany; 2 CECAD Cologne, University of
Cologne, Cologne, Germany
5439 — A0013 A new conjunctival melanoma model of primary and metastatic tumor growth.
Jinfeng Ca o 1 , N. de Waard 1 , A. A.
Mulder 1 , B. R. Ksander 2 , M. Jager 1 .
1 Ophthalmolgy,
Leiden University Medical Center, Warmond,
Netherlands; 2 Ophthalmology, Schepens Eye
Research Institute / Mass Eye & Ear, Harvard,
Boston, MA
5440 — A0014 Role of the Renin-
Angiotensin System in Human Conjunctival
Lymphoma.
Erdal Tan Ishizuka , A.
Kanda, S.
Kase , S.
Kinoshita, S.
Takashina, Y.
Dong , K.
Noda ,
S.
Ishida . Laboratory of Ocular Cell Biology and
Visual Science, Department of Ophthalmology,
Hokkaido University Graduate School of Medicine ,
Sapporo, Japan
5441 — A0015 Prognosis of lymphomas developed in the ocular adnexa: A single-center study.
Yoshiko Matsumoto 1 , A. Azumi 2 , A. Akashi 1 ,
M. Sakamoto 1 , T. Nagai 1 , M. Nakamura 1 .
1 Devision of Ophthalmology, Kobe University Graduate
School of Medicine, Kobe, Japan; 2 Ophthalmology,
Kobe Kaisei hospital, Kobe, Japan
5442 — A0016 Prognostication in Ocular
Adnexal Lymphoma - Feasibility of the
Latest Tumour, Tode, Metastasis Staging
System.
Peter Rasmussen 2, 1
T. Finger
McKelvie
4
7
, E. O. Graue
, K. Mulay 6
4
, S. E. Coupland
, H. E. Grossniklaus
, J. Prause 2
5
3 , P.
, P.
, E. Ralfkiaer
S. Heegaard 2, 1 . 1
Glostrup Hospital, University of Copenhagen,
Glostrup, Denmark;
8 ,
Department of Ophthalmology,
University of Copenhagen, Copenhagen,
Denmark; 3
2 Eye Pathology Institute,
Department of Cellular and Molecular
Pathology, University of Liverpool, Liverpool,
Liverpool, United Kingdom;
New York City, NY; 5
4 Department of Ocular
Oncology, The New York Eye Cancer Center,
Emory Eye Center, Section of Ocular Oncology, Emery University, Atlanta,
GA; 6 Prasat Eye Institute, Kallam Anji Reddy
Campus, Hyderabad, India; 7 The Orbital Plastic and
Lacrimal Clinic, The Royal Victorian Eye and Ear
Hospital, Melbourne, VIC, Australia;
Copenhagen, Copenhagen, Denmark
8 Department of Pathology, Rigshospitalet, University of
5443 — A0017 IgG4 Immunostaining in
Patients with Orbital Sarcoidosis: A Pilot
Study.
Kateki Vinod 1 , J. Spindle 2 , T. Milman 1 , R.
Shinder 2 .
1 Ophthalmology, New York Eye and Ear
Infirmary, New York, NY; 2 Ophthalmology, SUNY
Downstate Medical Center, New York, NY
5444 — A0018 IgG4-related ophthalmic disease: A clinicopathological study of 40 cases.
Shunichiro Ueda 1, 2
K. Kimura
T. Nagao 2
1
.
1
, K. Umazume
University, Tokyo, Japan;
, H. Goto
1
2
1 , Y. Usui
, J. Matsubayashi
Ophthalmology, Tokyo Medical
2
1 ,
,
Anatomic Pathology,
Tokyo Medical University, Tokyo, Japan
5445 — A0019 Primary Epithelial
Malignancies of the Lacrimal Gland: Trends in
Survival.
Maxwell Elia 1 , C. Tuggle 2 , J. Servat 1 ,
F. Levin 1 .
1 Ophthalmology, Yale University
School of Medicine, New Haven, CT; 2 Plastic and
Reconstructive Surgery, Yale University School of
Medicine, New Haven, CT
5446 — A0020 Selective Uptake of
Vital Stains in Orbital and Periorbital
Tissues.
Nicole Nikolic 1, 2 , J. Qiao
Yoo 1, 2 .
1
School of Medicine, Chicago, IL; 2
1 , P. Bu , D. K.
Ophthalmology, Loyola University Stritch
Ophthalmology,
Hines Veterans Affairs Hospital, Hines, IL
1, 2
Exhibit/Poster Hall SA A0021-A0066
Thursday, May 08, 2014 8:30 AM-10:15 AM
Clinical/Epidemiologic Research / Retina
Moderators: Lisa J. Keay and Pirro G. Hysi
5447 — A0021 Introduction of the Trauma
Image Bank.
Justin M.
Roman, C.
M.
Proctor,
G.
N.
Magrath, L.
P.
Perry.
Storm Eye Institute,
Medical University of South Carolina , Charleston ,
SC
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
366

Thursday – Posters – 5448 – 5473
5448 — A0022 Characterization of Corneal
Features in Ocular Graft Versus Host Disease by in vivo Confocal Microscopy.
Tudor C. Tepelus 1
G. Chiu
L. Lee
2
1, 2
, J. Maram
.
1
1 , V. Chopra 1, 2 , S. R. Sadda 1, 2
,
, O.
Doheny Image Reading Center, Doheny
Eye Institute, Los Angeles, CA; 2 USC Eye Institute,
Keck School of Medicine, Los Angeles, CA *CR
5449 — A0023 Evaluation of conjunctival scarring in graft-versus-host disease.
Surendra
Basti, R.
Ram, D.
Borkar . Ophthalmology,
Northwestern University , Feinberg School of
Medicine , Chicago, IL *CR
5450 — A0024 Follicular conjunctivitis:
5-year frequency of clinical diagnosis in a reference institution in Mexico City.
Paulina
Nunez, J.
Quevedo-Martínez , M.
Álvarez-López, J.
SernaOjeda.
Instituto de Oftalmologia Conde de
Valenciana , Mexico city , Mexico
5451 — A0025 Exposure to an Indoor Cooking
Fire and Risk of Active Trachoma in Children,
Kongwa, Tanzania.
Beatriz E.
Muno z 1 , H.
Mkocha 2 , S. K. West 1 . 1 Ophthalmology, Johns
Hopkins Wilmer Eye Inst, Baltimore, MD; 2 Kongwa
Trachoma Project, Kongwa, United Republic of
Tanzania
5452 — A0026 Screening for Trichiasis Using a
Novel System in Tanzania.
E. Munoz 2 , H. Mkocha
S. L. Merbs 2 .
1
3
Gregory Greene
, A. Majeed 3
1, 2
, S. K. West
, B.
Bloomberg School of Public Health, Baltimore,
MD; 2
2, 1
International Health, Johns Hopkins
,
Dana Center for Preventative Ophthalmology,
Johns Hopkins Medical Institutes, Batlimore,
MD; 3 Kongwa Trachoma Project, Kongwa, United
Republic of Tanzania f
5453 — A0027 Evolution of penetrating keratoplasty in a reference hospital in Mexico
City a five years study.
Cristina Fernandez, O.
Fernandez, R.
Velasco, O.
Baca , A.
Babayan, E.
D.
Alegria, C.
Pacheco Del Valle.
Cornea , Hospital de la Luz, Distrito Federal, Mexico
5454 — A0028 Evolution of indications and surgical techniques of corneal graft: retrospective study about 501 grafts.
Oualid
Guechi, L. Louis, C. Ghetemme, A. Jeancolas, A.
Agapie, F. Ameloot, S. Premy, J. Perone. Regional
Hospital Center of METZ, METZ, France
5455 — A0029 Conjunctival swabs of cornea donors and medium contamination.
André
P.
Klamann 1 , C. Hildebrandt 2 , A. K. Gruenert 1 ,
G. Geerling 1 , T. A. Fuchsluger 1 .
1 Augenklinik,
Heinrich Heine Universität Düsseldorf, Düsseldorf,
Germany; 2 Institut für theoretische Physik, Heinrich
Heine Universität, Düsseldorf, Germany
5456 — A0030 Incidence of Stevens-
Johnson Syndrome and Chemical Burns to the Eye. Relevance for Keratoprosthesis
Surgery.
Michelle White 1, 2 , J. Chodosh
Dohlman 1, 2 .
1 and Ear Infirmary, Boston, MA; 2
School, Boston, MA
1, 2 , C. H.
Ophthalmology, Massachusetts Eye
Harvard Medical
5457 — A0031 Epidemiology, risk factors, and microbiological profiles of infectious corneal ulcers in Southeastern Louisiana.
Namita
Bhardwaj 1, 2 , P. Shah 1 .
1
2 Ophthalmology, Louisiana State University, New
Orleans, LA
Ophthalmology,
Ochsner Clinic Foundation, New Orleans, LA;
5458 — A0032 Microbiome Diversity on Worn
Contact Lenses and Bacterial Communities
Associated with Care Solution Use and Lid
Bioburden.
Mauricio Retuerto , L.
Szczotka Flynn,
P.
Mukherjee, G.
Stoll, J.
Chandra, S.
Debanne,
Y.
Jiang, M.
Ghannoum . Case Western Reserve
University , Cleveland, OH *CR, f
5459 — A0033 Peripheral hypertrophic subepithelial corneal opacification.
Gerd
Geerling 1 , M. Schargus 2 , A. Gericke
4 , W. Lisch 1
3 , U.
Ophthalmology, Schlotzer-Schrehardt 3 .
University of Duesseldorf, Duesseldorf, Germany;
2 Ophthalmology, University of Wuerzburg,
Wuerzburg, Germany; 3 Ophthalmology,
Johannes Gutenberg University Mainz, Mainz,
Germany; 4 Ophthalmology, University of Erlangen-
Nuernberg, Erlangen, Germany
5460 — A0034 Environmental proteinaceous corneal degeneration: prevalence in different regions of Argentina.
Leandro Correa 1 , J. A.
Urrets-Zavalia 1 , M. F. Suarez 2 , R. Monti 1 , E.
Espósito 1 , E. González-Castellanos 1 , H. M.
Serra 2 . 1 Ophthalmology, Clínica Universitaria
Reina Fabiola, Universidad Católica de Córdoba,
Córdoba, Argentina; 2 CIBICI, Faculty of Chemical
Sciences, Universidad Nacional de Córdoba,
Córdoba, Argentina
5461 — A0035 Characterization of
Corneal Involvement in Eyes with Mucous
Membrane Pemphigoid by in vivo Confocal
Microscopy.
Olivia L.
Le e 1, 2 , T. C. Tepelus , S.
Ophthalmology, USC Doheny Eye
Institute, Los Angeles, CA; 2
2
R. Sadda 1, 2 . 1
Doheny Image Reading
Center, Doheny Eye Institute, Los Angeles, CA *CR
5462 — A0036 Demographic profile, clinical features and outcome of peripheral ulcerative keratitis.
Hemant Kamble , N.
Sharma , G.
Sinha, J.
S.
Titiyal, T.
Agarwal, B.
Chawla , R.
Tandon , R.
B.
Vajpayee . ophthalmology, AIIMS, New Delhi, India
5463 — A0037 Epidemiological characteristics, risk factors and antibiotic sensitivity of infectious keratitis in a High Referral Hospital in Mexico
City for the past 5 years. Andres Benatti
N. Ramos Betancourt
Hernandez-Quintela 1
1 , V. Vanzzini Zago 2
, F. Beltran 1
Corneal and Refractive Surgery, APEC, Ciudad de México, Mexico; 2
. 1
1 ,
, E.
Department of
Department of Microbiology,
APEC, Ciudad de México, Mexico
5464 — A0038 Surgical Interventions for
Microbial Keratitis: a Four-Year Experience in
Pennsylvania.
Liwu G.
Chen , K.
M.
Hammersmith,
P.
Nagra, N.
Ni , C.
J.
Rapuano.
Cornea , Wills Eye
Hospital , Philadelphia , PA
5465 — A0039 Frecuency Of Etiologic Agents
In Infectious Keratitis.
Elisa D.
Alegria, R.
Velasco, A.
Babayan, O.
Fernandez, O.
Baca .
Cornea , Hosp Nuestra Senora De La Luz IAP,
Mexico , Mexico
5466 — A0040 Topical steroid use prior to diagnosis exacerbates Acanthamoeba keratitis.
Nicole A. Carnt 1, 2 , D. Robaei 1 , D.
Minassian 3 , J. K. Dart 1, 2 .
1 Moorfields Eye
Hospital NHS Foundation Trust, London,
United Kingdom; 2 Institute of Ophthalmology,
University College London, London, United
Kingdom; 3 EpiVision Ophthalmic Epidemiological
Consultants, London, United Kingdom *CR
5467 — A0041 Epidemiology of Ulcerative
Keratitis: Bronx Experience.
Susan Huang, A.
Crossan, G.
Honik, D.
C.
Gritz.
Ophthalmology,
Albert Einstein / Montefiore Medical Center , Bronx,
NY
5468 — A0042 Seasonality of microbial keratitis on the Federal University of Sao
Paulo Ocular Microbiology Laboratory.
Fabio
I.
Marujo , F.
E.
Hirai, M.
Z.
Yu , A.
L.
Hofling-
Lima , D.
Freitas, E.
H.
Sato . Department of
Ophthalmology and Visual Sciences , Paulista
School of Medicine , São Paulo Hospital , Federal
University of São Paulo, São Paulo, Brazil
5469 — A0043 Microbial Keratitis.
Daniel
Sand 1 , D. Chen
Y. Hsu 1, 2 .
1
3 , M. Schur 3 , I. A. Shulman 4, 5 , H.
Ophthalmology, LAC+USC Medical
Center, Los Angeles, CA; 2 USC Eye Institute,
Keck Medical Center of USC, Los Angeles, CA;
3 Keck School of Medicine, University of Southern
California, Los Angeles, CA; 4 Department of
Pathology, Keck School of Medicine at USC, Los
Angeles, CA; 5 Pathology and Laboratory Medicine,
LAC+USC Medical Center, Los Angeles, CA
5470 — A0044 A Twelve- Year Review of
Demographics, Characteristics, and Outcomes of Open Globe Injuries (OGIs) Related to Vehicle Accidents (VAs).
Christopher K.
Orr 1, 2 , A. Bauza 2 , P. D. Langer 2 , M. Zarbin 2 ,
N. Bhagat 2 .
1 Opthalmology, Drexel University
College of Medicine, Philadelphia, PA; 2 Institute of
Ophthalmology and Visual Science, Rutgers, New
Jersey Medical School, Newark, NJ
5471 — A0045 Ruptured Globes at Montefiore:
Causes and Effects.
Medow 2 .
1 Byers Eye Institute at Stanford
University, Palo Alto, CA;
York, NY
Anjum Cheema
2
1, 2 , N.
Ophthalmology and
Visual Sciences, Montefiore Medical Center, New
5472 — A0046 The Clinical Features of
Geriatric Ocular Trauma in a Regional
Emergency Medical Center in Korea.
Seung
W.
Lee, Y.
Ko. Department of ophthalmology,
Dongguk Universtiy, Gyeongju, Republic of Korea
5473 — A0047 Spectacle wear, airbag deployment and eye trauma.
Timo M. Tervo 1 , P.
Sulander 2 , T. Koisaari
Helsinki, Finland
2 .
1 Ophthalmology, University of Helsinki, Helsinki, Finland; 2 Traffic Insurer, f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
367

Thursday Posters 8:30 am – 10:15 am
5474 – 5498 – Thursday – Posters
5474 — A0048 Hospitalized Eye Injuries from
United States Emergency Departments.
Yasir
Ahme d 1 , J. G. Linakis
Greenberg 1
2, 3 , M. J. Mello 2 , P. B.
Ophthalmology, Penn State Hershey 4, 5 .
Medical Center, Hershey, PA;
Medicine, Warren Alpert Medical School of Brown
University, Providence, RI;
2 Emergency
3 Pediatrics, Warren
Alpert Medical School of Brown University,
4 Ophthalmology, Warren Alpert Providence, RI;
Medical School of Brown University, Providence,
RI; 5 Ophthalmology, Veterans Affairs Medical
Center, Providence, RI
5475 — A0049 Characteristics and
Demographics of Patients with Posterior
Segment Intraocular Foreign Bodies.
Poonam
Misra 1, 2 , S. M. Abbassi 1, 2 , A. Bauza 1, 2 , M. Zarbin 1, 2 ,
N. Bhagat 1, 2 .
1 Institute of Ophthalmology and
Visual Science, Newark, NJ; 2 Rutgers, New Jersey
Medical School, Rutgers, The State University of
New Jersey, Newark, NJ
5476 — A0050 Correlation of Radiographic
Muscle Entrapment with Diplopia and
Restriction of Extraocular Movements in
Patients with Orbital Fractures.
Elizabeth
Chiang 1 , L. V. Saadat
D. French 1
2 , J. A. Spitz
, C. B. Chambers 1
2 , P. Bryar 1 ,
1 . Ophthalmology,
Northwestern University Feinberg School of
Medicine, Chicago, IL; 2 Northwestern University
Feinberg School of Medicine, Chicago, IL
5477 — A0051 Management of Canalicular
Lacerations: Epidemiological Aspects and
Experience.
Ashley Campbell 1, 2 , D. K. De
Castro 1, 2 , N. G. Lee 1, 2 , S. K. Freitag 1, 2 , D.
R. Lefebvre 1, 2 .
1 Ophthalmic Plastic Surgery,
Massachusetts Eye and Ear Infirmary, Boston,
MA; 2 Ophthalmology, Harvard Medical School,
Boston, MA
5478 — A0052 Emergency Ophthalmic Care in the Disaster Setting: A Survey of Urgent
Care Visits at the New York Eye and Ear
Infirmary During Hurricane Sandy.
Dipika Joshi.
Ophthalmology, New York Eye and Ear Infirmary,
New York , NY
5479 — A0053 Sensitivity and Specificity of Computed Tomography Findings in the
Diagnosis of Combat-related Open-globe
Injuries.
R Joel Welc h 1 , Q. Nguyen 1 , S. R.
OConnell 2 . 1 Truhlsen Eye Institute, University of
Nebraska Medical Center, Omaha, NE; 2 Department of Ophthalmology, Naval Hospital Camp Pendleton,
Camp Pendleton, CA
5480 — A0054 Open Globe Injuries and the
Incidence of Sympathetic Ophthalmia at a Large
County Hospital.
Shaam Mahasneh , P.
Redmond,
R.
Mancini.
Ophthalmology, University of Texas
Southwestern Medical Center at Dallas , Dallas , TX
5481 — A0055 A Multivariate Analysis of Legal
Vision Requirements and MVC Fatalities in the
U.S.
Melinda Exume, G.
Martorana, A.
Nading , M.
B.
Sherwood . University of Florida, Gainesville, FL
5482 — A0056 Meta-Analysis: Golf-Related
Ocular Injuries.
Elliot S. Crane 1 , A. M.
Kolomeyer 3 , E. Kim 1 , D. S. Chu 2, 4 .
1 New Jersey
Medical School - Rutgers University, Newark,
NJ; 2 Department of Ophthalmology & Visual
Science, New Jersey Medical School - Rutgers
University, Newark, NJ; 3 Eye & Ear Institute,
University of Pittsburgh School of Medicine,
Pittsburgh, PA; 4 Metropolitan Eye Research and
Surgery Institute, Palisades Park, NJ *CR
5483 — A0057 Outcomes Following Traumatic
Hyphema in a Pediatric Population.
Laura J.
Kopplin 1 , M. F. Chiang 1, 2 , D. Karr 1 .
1 Department of Ophthalmology, Casey Eye Institute, Portland,
OR; 2 Department of Medical Informatics & Clinical
Epidemiology, Casey Eye Institute, Portland, OR
5484 — A0058 Pediatric Corneal Injuries from Laundry Detergent Pods.
Constance E.
West 1, 2 , M. E. Gray 1, 2 . 1 Division of Pediatric
Ophthalmology, Cincinnati Children’s Hospital
Medical Center, Cincinnati, OH; of Ophthalmology, University of Cincinnati,
Cincinnati, OH
2 Department
5485 — A0059 Detergent capsule ocular injuries; An emerging risk in the United
States.
Robert Glazie r 1 , E. McCourt 1 ,
R. Mets-Halgrimson 2 , R. Enzenauer 1 , R.
Braverman 1 .
1 Ophthalmology, University of Colorado, Aurora, CO; 2 Ophthalmology,
Northwestern University, Chicago, IL
5486 — A0060 Ocular injuries from the impact of collapsible laundry hamper wires.
Thomas
Wubben 1 , A. Khan 2 , Y. I. Leiderman 1 , F. Chau
T. J. Royston 2, 3 , I. S. Kassem 1 .
1 and Visual Sciences, University of Illinois at
Chicago, Chicago, IL;
1
Ophthalmology
,
Engineering, University of Illinois at Chicago,
Chicago, IL; 3
2 Mechanical and Industrial
Bioengineering, University of Illinois at Chicago, Chicago, IL
5487 — A0061 Ocular Trauma in South Texas:
Establishing an Open Globe Registry.
Olga
Shif , A.
Pazandak , S.
R.
Cohen, M.
R.
Jardeleza.
Ophthalmology, UTHSCSA, San Antonio, TX
5488 — A0062 Orbital Fractures: Patient
Demographics, Etiology and Clinical
Presentation.
Lily V.
Saadat 1 , E. Chiang 2 ,
J. A. Spitz
Chambers
1
2
, P. Bryar
.
1
2 , D. French
Northwestern University Feinberg
School of Medicine, Chicago, IL; 2
Medicine, Chicago, IL
2 , C. B.
Ophthalmology,
Northwestern University Feinberg School of
5489 — A0063 Analysis of Decreased Vision with Facial Fractures.
Jared A.
Spitz, E.
Chiang ,
L.
Saadat , P.
Bryar, D.
French , C.
B.
Chambers .
Ophthalmology, Northwestern University , Feinberg
School of Medicine , Chicago, IL
5490 — A0064 A prospective study on the incidence and pattern of orbital fractures and ocular complications in two wheeler drivers following road traffic accidents in South
India.
Sahebaan Sabharwal, S.
Prabhakar, R.
Ravindran.
Ophthalmology, Sri Ramachandra
University , Chennai, India
5491 — A0065 Frequency of Ocular Injury, and Examination Findings Predictive of
Serious Ocular Injury, in Patients with Orbital
Fractures.
John Fileta , I.
U.
Scott.
Penn State
Hershey Eye Center , Hershey, PA
5492 — A0066 The Availability of Modified
Ocular Trauma Score in Korean Patients with
Open Globe Injury.
Haeng Jin Lee, K.
Kim,
J.
Kim, S.
Lee.
Chungnam National University
College of Medicine , Daejeon, Republic of Korea
Exhibit/Poster Hall SA A0067-A0096
Thursday, May 08, 2014 8:30 AM-10:15 AM
Cornea
Moderator: Ilene K. Gipson
5493 — A0067 CD147 is Required for Meibomian Gland Development and Differentiation.
Dieckow
Argueso 1
1
.
1
Jerome
, E. E. Gabison 2 mauris 1 , J.
, R. A. Nowak 3 , P.
Ophthalmology, schepens Eye Rsrch Inst,
MEEI, HMS, Boston, MA; 2
Bichat, APHP, Université Paris VII Diderot, Paris,
France; 3 Department of Animal Sciences, University of Illinois, Urbana, IL
Cornea and External
Diseases, Fondation A. De Rothschild, Hôpital
5494 — A0068 Progression of the Meibomian
Gland Disease and Lid Margin Keratinization in Conditional Notch1 Knockout mice.
Sanaz
Gidfar , A.
Movahedan, N.
Afshar , H.
Sagha, A.
R.
Djalilian.
Ophthalmology and Visual Sciences ,
University of Illinois at chicago, Chicago, IL
5495 — A0069 Tissue-Specific Knockout of
Connective Tissue Growth Factor in the Cornea and Lens Epithelia Results in an Aniridia-
Like Phenotype.
Daniel J.
Gibson 1
S. Schultz 1 . 1
Gainesville, FL; 2
Gainesville, FL
, L. Pi 2 , G.
OB/GYN, University of Florida,
Pediatrics, University of Florida,
5496 — A0070 Inflammatory changes in barrier deficient corneas in conditional Notch1 knockout mice.
Ali R.
Djalilian, A.
Movahedan, N.
Afshar , M.
Eslani . Ophthalmology, Univ of Illinois at Chicago, Chicago, IL
5497 — A0071 Stratification of the Corneal
Epithelium is Disrupted in the Absence of Vangl2.
Domenico A.
Panzica, J.
Collinson.
University of Aberdeen , Aberdeen , United
Kingdom
5498 — A0072 Effects of Vitamin D Receptor
Knockout on Cornea Epithelium Gap
Junctions.
Mitchell A.
Watsky 1, 2 , X. Lu 1 . 1 Cell
Biology and Anatomy, Georgia Regents University,
Augusta, GA; 2 The Graduate School, Georgia
Regents University, Augusta, GA
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
368

Thursday – Posters – 5499 – 5522
5499 — A0073 Macrophage Heme Oxygenase
2 is necessary but not sufficient for successful corneal wound healing response.
Lars
Bellner 1 , M. Covey 1 , M. W. Dunn 1, 2 , M.
Schwartzman 1, 2 .
1 Pharmacology, New York Medical
College, Valhalla, NY; 2 Ophthalmology, New York
MEdical College, Valhalla, NY
5500 — A0074 Inhibition of Kir4.1 (KCNJ10) produces EGF-like effect in corneal epithelial cells.
Daohong Lin, C.
Zhang, L.
Wang , X.
Su .
Pharmacology , New York Medical College,
Valhalla , NY
5501 — A0075 Stimulation of PEDF-R in
Rabbit Corneal Epithelial Cells Induces a Rapid
Release of DHA.
Azucena H.
Kakazu , B.
Jun, E.
J.
Knott, N.
G.
Bazan, H.
E.
Bazan.
Ophthalmology/
Neuroscience Center , LSU Health Sciences Center ,
New Orleans, LA
5502 — A0076 Small Molecule Induction
Promotes Corneal Epithelial Cell Differentiation from Human Pluripotent Stem Cells.
Alexandra
Mikhailova 1, 2 , T. Ilmarinen 1, 2
4 , H. Skottman 1, 2 .
1
, H. M. Uusitalo 3,
Institute of Biomedical
Technology, University of Tampere, Tampere,
Finland; 2 BioMediTech, Tampere, Finland;
Department of Ophthalmology, University
3 SILK, of Tampere, Tampere, Finland;
Finland *CR
4 TAUH Eye
Center, Tampere University Hospital, Tampere,
5503 — A0077 Krt12Cre gene Expression is required demethylation of CpG island and Exon1.
Yasuhito Hayashi 1, 2 , N. Higuchi 1 ,
N. Takahira 1 , Y. Ohashi 1 , W. W. Kao 2 .
1 Dept of Ophthalmology, Ehime University, Toh-on,
Japan; 2 Ophthalmic Research Laboratories
& Crawley Vision Science Research Center,
University of Cincinnati, Cincinnati, OH
5504 — A0078 Functional Characterization of the Glucocorticoid Receptor in the
Cornea.
Mahita Kadmiel, J.
A.
Cidlowski.
NIEHS/
NIH, Durham , NC
5505 — A0079 Gap Junction Diffusion
Coefficients in Mouse Cornea Epithelium and
Keratocytes.
Xiaowen Lu , M.
A.
Watsky . Cellular
Biology and Anatomy, Georgia Regents University ,
Augusta, GA
5506 — A0080 Investigation of protein kinase
C alpha in corneal epithelial cells derived from a gelatinous drop-like corneal dystrophy patient.
Koji Kitazawa 1 , S. Kawasaki 2, 1 , M. Ueno 1 ,
H. Tanaka 1 , K. Shinomiya 1, 3
S. Kinoshita 1 .
1
Kyoto, Japan; 2
, M. Nakatsukasa 1 ,
Kyoto Prefectural Univ of Med,
Osaka, Japan; 3
Ophthalmology, Osaka Univ,
Ophthalmic Research Center, R&D
Division, Santen Pharmaceutical Co., Ltd., Ikoma,
Japan
5507 — A0081 Functional Implication of CXCL14 Chemokine during Cornea
Development.
Ana Ojeda, P.
Y.
Lwigale.
Biochemistry and cell biology, Rice University ,
Houston, TX
5508 — A0082 Biofunctionalized heavy metal free quantum dots (QD) as a tool for tracking transplanted limbal epithelial cells.
Nuria
Genicio 1, 2 , J. Gallo 3 , M. Dziasko 1 , N. J. Long 3 ,
A. J. Shortt 1, 2 .
1 Ocular Biology and Therapeutics,
UCL Institute of Ophthalmology, London, United
Kingdom; 2 NIHR BRC, Moorfields Eye Hospital,
London, United Kingdom; 3 Comprehensive Cancer
Imaging Centre, Imperial College London, London,
United Kingdom
5509 — A0083 Metagenomic data mining for ocular surface microbiome research.
Alexander I.
V. Shestopalov 1, 3 . 1
Tuzhikov 1, 2 , A. U. Panchin 2
Ophthalmology-McKnight
Rsch Ctr, Univ of Miami Miller Sch of Med,
Miami, FL; 2 Kharkevich Institute for Information
Transmission Problems, Moscow, Russian
Federation; 3 Vavilov Institute of General Genetics,
Moscow, Russian Federation
,
5510 — A0084 Diadenosine tetraphosphate modifies corneal epithelial tight junction assembly and barrier permeability.
Ana Guzman -
Aranguez , P.
Loma , M.
Perez de Lara , J.
Pintor .
Biochemistry and Molecular Biology, Complutense
University , Madrid , Spain
5511 — A0085 The Change of Tight Junction-
Related Protein Expression in Human
Telomerase Reverse Transcriptase (hTERT)
Immortalized Corneal and Conjunctival
Epithelial Cells by Viral Double-Strand RNA
Stimulation.
Keiko Yamada 1, 2
Kinoshita 2 .
1
Hospital, Nantan, Japan; 2
, Y. Ban 1, 2 , S.
Ophthalmology, Nantan General
Ophthalmology, Kyoto prefectural university of medicine, Kyoto, Japan
5512 — A0086 A Novel Method for Testing
Tight Junction Function in Cultured Epithelial
Cell Sheets.
Thomas Duncan , K.
Baba , Y.
Oie, K.
Nishida.
Department of Ophthalmology, Osaka
Graduate School of Medecine , Suita-shi, Japan
5513 — A0087 A potential role of PPARγ in corneal epithelial differentiation program.
Ewa
A. Meyer 1 , M. Zenkel 1
Menzel-Severing 1
, N. Polisetti 1
, M. K. Call
U. Schlotzer-Schrehardt 1 .
1
2
, J.
, F. E. Kruse
Germany; 2 Ophthalmology, University of
Cincinnati, Cincinnati, OH
1 ,
Ophthalmology,
University of Erlangen-Nuernberg, Erlangen,
5514 — A0088 Flow Cytometry Analysis of Inflammatory Biomarker HLA-DR for
Multicenter Clinical Trials of Ocular Surface
Disease.
Seth P.
Epstein, P.
A.
Asbell , N.
J.
Gadaria-
Rathod , Y.
Wei.
Ophthalmology, Icahn School of
Medicine at Mount Sinai, New York , NY f
5515 — A0089 Corneal epithelial cell bank; newly developed sheet manufacturing technology that allows the production of stable human corneal epithelial cell sheet.
Kiwamu
Imagawa 1 , K. Maeda 1
S. Watanabe 1
, S. Yokoyama
, T. Nakamura 2 , S. Kinoshita pharmaceuticals, Kobe, Japan; 2
1 , Y. Hosoda 1
3 .
1 JCR
,
Research Center for
Inflammation and Regenerative Medicine Faculty of Life and Medical Sciences Doshisha University,
Kyoto, Japan; 3 Ophthalmology, Kyoto Prefectural
University of Medicine, Kyoto, Japan *CR f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
369
5516 — A0090 Activation of Caspase-6 in Human Corneal Limbal Epithelial Cells
Exposed to UVB.
John L.
Ubels, M.
P.
Schotanus.
Department of Biology, Calvin College, Grand
Rapids , MI
5517 — A0091 MicroRNA-494 is Highly
Expressed in Human Cornea Epithelium
Cells(HCECs) and inhibits Nerve Growth
Factor(NGF)-Induced Cell Proliferation through
Targeting Cyclin D1.
Dan Wu , J.
Hong , J.
Xu .
Ophthalmology and Visual Science, Shanghai Eye
& ENT Hospital of Fudan University , Shanghai ,
China
5518 — A0092 Effect of NecroX-5, a novel necrosis inhibitor, on the survival of cultivated oral mucosal epithelial sheets.
Dong Won Hyun 1, 2
3 , S. Jeon 3 , W. Wee 1, 2 , A. Koh
M. Kim
2 , Y. Kim
1, 2
University College of Medicine, Seoul, Republic of Korea; 2
. 1
3 , E. Shin
Ophthalmology, Seoul National
Laboratory of Ocular Regenerative
Medicine and Immunology, Seoul Artificial
Eye Center, Seoul National University Hospital
Clinical Research Institute, Seoul, Republic of
Korea; 3 Cutigen Research Institute, Tego Science
Inc., Seoul, Republic of Korea
,
5519 — A0093 Efficacy of heparin sulfate mimetic polymer in Cogan’s epithelial dystrophy.
Marc Labetoulle 1, 2 , A. Rousseau 1 , M.
M’Garrech
E. Barreau 1
1 , G. Kaswin
, T. Bourcier
1
4
, B. Dupas 3 , C. Baudouin 3
.
1 Ophthalmology,
Hopital Bicetre, South Paris University, Le
,
Kremlin Bicetre, France; 2 Laboratoire de Virologie
Moleculaire et Structurale, CNRS UPR 3296, Gif sur Yvette, France;
France; 4
Strasbourg, France
3 CHNO Quinze-Vingts, Paris,
Ophthalmology, Nouvel Hopital Civil,
5520 — A0094 Orphan Drug for
Acanthamoeba Keratitis (ODAK) project: results of a 10-Year retrospective study in Italy and in the United Kingdom.
Vincenzo Papa
P. Rama
Italy; 2
Italy; 3
2 , F. Ferrario
C. Radford 3
2 , A. Ramoni
, J. K. Dart 3 .
1
2 , S. Matuska
SIFI SPA, Catania,
San Raffaele Scientific Institute, Milan,
Moorfields Eye Hospital NHS Foundation
Trust, London, United Kingdom *CR
1 ,
2 ,
5521 — A0095 Exclusion of pathogenic coding region mutations in the Xp22.3 locus associated with Lisch epithelial corneal dystrophy using next-generation sequencing.
Doug D.
Chung, R.
F.
Frausto, A.
J.
Aldave . Cornea Division , Jules Stein
Eye Institute, UCLA , Los Angeles, CA
5522 — A0096 Microfabricated niches for the culture of limbal epithelial cells.
Charanya
Ramachandran
F. Claeyssens 2
V. S. Sangwan 1
1 , I. Ortega 2
, A. J. Ryan 3
, S. Macneil
, F. Sefat 2 , P. Deshpande 2
, D. Balasubramanian
2 .
1 Centre for Ocular
1 ,
Regeneration, LV Prasad Eye Institute, Hyderabad,
India; 2 Department of Material Science and
Engineering, University of Sheffield, Sheffield,
United Kingdom; 3 Department of Chemistry,
University of Sheffield, Sheffield, United Kingdom
,

Thursday Posters 8:30 am – 10:15 am
5523 – 5543 – Thursday – Posters
Exhibit/Poster Hall SA A0097-A0120
Thursday, May 08, 2014 8:30 AM-10:15 AM
Cornea
Moderator: Harumitsu Hirata
5523 — A0097 Assessment of corneal epithelial thickness in dry eye patients evaluated by Fourier-domain optical coherence tomography.
Xinhan Cui, J.
Hong , F.
Wang , Y.
Yang , J.
Xu . Ophthalmology, Eye and ENT Hospital of Fudan University , Shanghai , China
5524 — A0098 Confocal microscopy: New tool for the follow-up of conjunctival intraepithelial neoplasia.
Vitor Maduro, L. vieira, R. Anjos,
A. Vicente, N. Alves. Ophthalmology, CHL-ZC,
Lisboa, Portugal
5525 — A0099 Normal development of central corneal thickness and intra-ocular pressure.
Ian
Cunningham , A.
Chandna.
Alder Hey Children › s
NHS Foundation Trust, Liverpool, United Kingdom
5526 — A0100 3-D epithelial mapping pattern assessment in normal and keratoconus eyes.
Elana S. Rosenberg
G. Asimellis 2 .
1
1 , A. J. Kanellopoulos 1, 2
Ophthalmology, New York
University School of Medicine, New York,
NY; 2 LaserVision.gr Eye Institute, Athens,
Greece *CR
,
5527 — A0101 Three-Dimensional Analysis of
Corneal Epithelial Nerves in Diabetes.
Matthew
S.
Yore k 1 , M. A. Yorek 1, 3 , R. H. Kardon 1, 2 . 1 Center for the Prevention and Treatment of Visual Loss,
Department of Veterans Affairs, Iowa City,
IA;
IA;
2
3
Ophthalmology, University of Iowa, Iowa City,
Internal Medicine, University of Iowa, Iowa
City, IA
5528 — A0102 Gamma-Glutamyl
Transpeptidase in Human Diabetic and Non-Diabetic Corneas.
Margaret
Young 1 , M. P. Langford
Chaudhery 2
1 , T. Redens 1 , S.
Ophthalmology, Louisiana State
University Health Sciences Center, Shreveport,
LA; 2
.
1
Pathology, Louisiana State University Health
Sciences Center, Shreveport, LA
5529 — A0103 Expression pattern of epithelial stem cell markers in the normal human cornea.
Michael J.
Nicolas, A.
P.
Moulin , F.
Majo .
Department of Ophthalmology, University of
Lausanne , Jules-Gonin Eye hospital , Lausanne ,
Switzerlan d
5530 — A0104 Analysis Of Expression Kinetics
Of Cell Cycle Machinery During Corneal
Epithelial Wound Healing And Epithelial
Growth Influenced By Growth Factors And
Extracellular Matrix.
Gudiseva Chandrasekher,
S.
Pothula.
Pharmaceutical Sciences , South Dakota
State University , Brookings, SD
5531 — A0105 TRPV-1 expression in cornea of diabetic rats.
Lara C.
Dias , A.
C.
Dias , L.
Nominato , E.
M.
Rocha.
Oftalmologia ,
Otorrinolaringologia e CCP, FMRP - USP, Ribeirão
Preto, Brazil
5532 — A0106 Lack of tyrosine phosphatase Shp2 in corneal epithelium impacts sensory innervation during development and homeostasis in adult mice.
Chia Yang Li u 1 , Y.
Zhang 1 , L. Yeh 2 , W. W. Kao 1 . 1 Ophthalmology,
University of Cincinnati, Cincinnati,
OH; 2 Ophthalmology, Chang-Gung Memorial
Hospital, Linko, Taiwan
5533 — A0107 Cultured limbal stem cell versus limbal tissue transplantation for treating severe limbal deficiency.
Vincent M. Borderie 1, 2
D. Ghoubay-Benallaoua 1, 2
O. Sandali 1 , E. Basli 1
Laroche 1, 2
Vingts, Paris, France;
France f
.
1
2
, N. Bouheraoua
, P. L. Goldschmidt 1, 2
1, 2 ,
, L.
Ophthalmology, CHNO des Quinze-
Institut de la Vision, Paris,
,
5534 — A0108 Prognostic factors in chronic complications of Stevens-Johnson syndrome and toxic epidermal necrolysis.
DongHyun
Kim 1, 2 , M. Kim 1, 2 , K. Yoon 3 , H. Lee 3 , K. Seo 4 ,
S. Yoon 4 .
1 Department of Ophthalmology,
Seoul National University College of Medicine,
Seoul, Republic of Korea; 2 Laboratory of Ocular
Regenerative Medicine and Immunology, Seoul
Artificial Eye Center, Seoul National University
Hospital Clinical Research Institute, Seoul,
Republic of Korea; 3 Department of Ophthalmology,
Chonnam National University Medical School,
Gwangju, Republic of Korea; 4 Department of
Ophthalmology, Institute of Vision Research, Yonsei
University College of Medicine, Seoul, Republic of Korea
5535 — A0109 Lateral Diffusion Coefficient in CXL with Corneal Channels.
Rebecca
M. McQuaid 1, 2 , J. Li 1 , M. Mrochen 2
Vohnsen 1 .
1
Dublin 4, Ireland; 2
Innocross, Zurich, Switzerland
, B.
Physics, University College Dublin,
Ophthalmology, IROC
5536 — A0110 Fibrin glue in cornea epithelial cell migration.
Aaron M.
Yeung, L.
A.
Faraj, O.
D.
McIntosh , H.
S.
Dua.
Ophthal & Visual Sciences ,
University of Nottingham , Nottingham , United
Kingdom
5537 — A0111 Conjunctival cell viability and apoptosis after one month of treatment with
Thealoz ® in dry eye subjects.
Hayette Rebika 1
A. López-Miguel
A. Corell 2, 3
3, 4
M. J. Gonzalez 2, 3 .
1
, R. Reinoso 2, 3
, I. Fernández 3
, C. Martín 2, 3
, M. Calonge de Valladolid, Spain, Valladolid, Spain;
2, 3 ,
R&D, Laboratoires Thea,
Clermont-Ferrand, France; 2
3 CIBER-
,
,
, IOBA, Universidad
BBN (Biomedical Research Networking Center in
Bioengineering, Biomaterials and Nanomedicine),
Spain, vallalolid, Spain; 4
Valladolid, Spain *CR , f
VISIÓN I+D, SL,
5538 — A0112 Blue Light-induced Oxidative
Stress in Human Corneal Epithelial Cells:
Protective Effect of Ethanol Extracts from
Mixture of Various Medicinal Plants.
Kyung
Chul Yoon
Lee 3
1 , Z. Li 1 , J. Woo 2 , S. Kim 3 , J.
Department of Ophthalmology, Chonnam .
1
National University Medical School and Hospital,
Gwangju, Republic of Korea;
Ophthalmology, Ulsan University Hosital, Ulsan,
Republic of Korea; 3
2 Department of
Department of Dermatology,
Chonnam National University Medical School and
Hospital, Gwangju, Republic of Korea
5539 — A0113 Novel primary epithelial cell toxicity assay using porcine corneal explant.
Hiroki Takahashi, K.
Tajima , T.
Hattori, H.
Goto . Ophthalmology, Tokyo Medical University ,
Shinjyuku-ku , Japan
5540 — A0114 DNA damage in Human
Limbal Epithelial Cells expanded ex vivo.
Yolanda Lorenzo Corrales
L. K. Drolsum
Nicolaissen 1, 3 .
1, 3
1
, M. Moe 1, 3
1, 2 , K. H. Berg
, A. R. Collins
Hospital.Center for Eye Research and The
2
1
, B.
,
Ophthalmology, Oslo University
Norwegian Eye Bank., Oslo, Norway; 2 Nutrition.,
Medical Faculty, University of Oslo., Oslo,
Norway; 3 Ophthalmology, University of Oslo.,
Oslo., Norway
5541 — A0115 Cytotoxicity Effect of Boric
Acid-based Multipurpose Contact Lens Care
Solutions (MPSs) on Human Corneal Epithelial
Cells HCET.
Kissaou T. Tchedre 1 , M. Imayasu 2 ,
Y. Hori 3 , C. H. Dwight 4 .
1 R&D and Innovation
Center, Menicon LTD, Le Mans, France; 2 2R&D and Innovation Center, Menicon LTD, Kasugai,
Japan; 3 Ophthalmology, Toho University Sakura
Medical Center, Sakura, Japan; 4 Ophthalmology,
Univ Texas Southwestern Med Ctr, Dallas, TX *CR
5542 — A0116 Improvement in Visual Function and Acuity with Prosthetic Replacement of the
Ocular Surface Ecosystem (PROSE) Treatment in Patients with Chronic Graft Versus Host
Disease.
A. Irvine 4
Christos Theophanous
.
1
1 , G. Chiu 2, 3 , J.
USC Keck School of Medicine, Los
Angeles, CA; 2
Angeles, CA;
CA; 4
3
Keck Medical Center of USC, Los
USC Ophthalmology, Los Angeles,
Ophthalmology, USC Keck School of
Medicine, Los Angeles, CA
5543 — A0117 Cultured Autologous Oral
Mucosal Epithelial Cell Sheet Grafts For
Treatment Of Experimentally-Induced Limbal
Stem Cell Deficiency.
Fawzia Bardag Gorc e 1 , R.
H. Hoft 3 , J. Oliva Vilana 1 , A. Wood 1 , D. Pan 1 , J.
Thropay 1 , A. Makalinao 1 , H. Sota 1 , S. W. French 2 ,
Y. Niihara 1 . 1 Hematology, LA BioMed at Harbor
UCLA Med Ctr, Torrance, CA; 2 Pathology, LA
3
BioMed at Harbor UCLA Med Ctr, Torrance, CA;
Surgery-Ophtalmogloy, LA BioMed at Harbor
UCLA Med Ctr, Torrance, CA *CR
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
370

Thursday – Posters – 5544 – 5566
5544 — A0118 Repeatability of Measurements from Fourier-Domain OCT for Detecting Ectatic
Diseases of Corneal Epithelial Thickness.
Ana
Laura C.
Canedo , B.
F.
Valbon , R.
Correa , R.
Ambrosio . Cornea & Refrative Surgery, Rio de
Janeiro Corneal Tomography & Biomechanics
Study Group, Rio de Janeiro, Brazil *CR
5545 — A0119 Vitamin D Activation and TLR2
Activity in Human Corneal Epithelial Cells.
Rose
Y.
Reins, H.
Badouri, A.
M.
McDermott.
College of
Optometry, Univ of Houston, Houston, TX
5546 — A0120 RNA processing of gamma secretase complex members, Pen2 and Nicastrin, corneal Epithelia.
Stephen P.
Sugrue , D.
Ryu, Q.
Peng , J.
Joo.
Anatomy & Cell Biology, University of Florida, Gainesville, FL
Exhibit/Poster Hall SA A0156-A0205
Thursday, May 08, 2014 8:30 AM-10:15 AM
Clinical/Epidemiologic Research / Retina
Moderators: Praveen J. Patel and Lisa Park
5547 — A0156 Reporting of Harms by Randomized Controlled Trials in
Ophthalmology.
Roderick O›Da y 1, 3
R. Blennerhassett
4 .
1
2 , M. C. Gillies 3
Hospital, Sydney, NSW, Australia;
, R. Walton
Royal Victorian Eye and Ear Hospital,
East Melbourne, VIC, Australia; 2 Westmead
3 Save Sight
Institute, University of Sydney, Sydney, NSW,
Australia; 4 Ophthalmology, University Hospital
Zurich, Zurich, Switzerland *CR
3
, D. Barthelmes
,
3,
5548 — A0157 Importance of Different
Barriers to Glaucoma Medication
Adherence.
Paula Anne Newman Case y 1 , T.
Blachley 1
Lee
MI;
1 .
1
, K. B. Farris 2 , A. L. Robin 3, 4 , P. P.
Ophthalmology & Vis Sci, Kellogg Eye
Center, University of Michigan, Ann Arbor,
2 College of Pharmacy, University of Michigan,
Ann Arbor, MI;
Baltimore, MD;
3
4
Ophthalmology, Johns Hopkins,
International Health, Johns
Hopkins, Baltimore, MD *CR
5549 — A0158 Evaluation of two metrics for identifying poor glaucoma medication adherence compared to objective adherence measurements.
B. Sleath
Muir 1, 4 .
1
3
Jaya Badhwar
, S. Danus 4
University, Durham, NC; 2
1, 4 , H. Bosworth 2, 4
, L. Christensen 1 , K. W.
Department of Ophthalmology, Duke
,
Chapel Hill, NC; 4
Department of
Medicine, Duke University, Durham, NC; 3 of Pharmacy, University of North Carolina,
School
Durham, NC
Health Services Research and Development, Durham VA Medical Center,
1
5550 — A0159 Association between Anxiety and Depression with the Frequency of Eye Drops in Inflammatory Eye Disease Patients.
Georgios
Vakros 1 , J. Hodson 2 , P. I. Murray 1 , S. Rauz
Academic Unit of Ophthalmology, Centre
1 . for Translational Inflammation Research,
University of Birmingham, Birmingham, United
Kingdom; 2 Wolfson Computer Laboratory, Queen
Elizabeth Hospital, Birmingham, United Kingdom
5551 — A0160 Real-World Analysis of the Time Associated with Adding a Second
Glaucoma Therapy in Newly Diagnosed OAG/
OHT Patients.
William Wong 1 , A. L. Cole 2 , J.
Chia 2 . 1 GHOSR, Allergan, Irvine, CA; 2 CHDA,
Allergan, Irvine, CA *CR
5552 — A0161 Use of eye care services among
US adults.
Asel Ryskulova, R.
Hines.
NCHS , CDC,
Hyattsville, MD
5553 — A0162 Ophthalmic Use of City
Hospital Emergency Services.
Ilyse D.
Haberman ,
E.
J.
Cohen, A.
Qureshi, L.
Park . Ophthalmology,
New York University , New York , NY
5554 — A0163 Characteristics of Inpatient
Ophthalmology Consults Associated with
Ocular Pathology and Need for Ophthalmologic
Intervention.
Jason Mayer
I. U. Scott 1 .
1
, Z. Landis 1
Ophthalmology, Penn State Hershey
Eye Center, Hershey, PA;
Hershey, PA
2
1 , M. Wang
Department of Public
Health Sciences, Penn State College of Medicine,
2 ,
5555 — A0164 The Scope of an Inpatient
Ophthalmology Consult Service Before and After
Hurricane Sandy.
Anam Qureshi, E.
J.
Cohen, I.
D.
Haberman , L.
Park . Ophthalmology, New York
University , New York , NY
5556 — A0165 Surgical outreach eye programs: a comparison of community-based vs. hospitalbased cataract surgery delivery.
E. Cole 2
MI;
, B. Badhu 3 , M. Sharma 4 .
1
Sushant Wagley 1
Medicine, Michigan State University, East Lansing,
2 Tufts University School of Medicine, Boston,
MA; 3
,
College of Human
Ophthalmology, BP Koirala Institute of
Health Sciences, Dharan, Nepal; 4 Ophthalmology,
Royal Australasian College of Surgeons, Dili,
Timor-Leste
5557 — A0166 Detection of Non-Glaucomatous
Ocular Pathology and Barriers to Follow-
Up in a Community Glaucoma Detection
Program.
Wanda D. Hu 1 , C. X. Hu 1 , J. Tran 1 ,
E. Pequignot 2 , M. Waisbourd 1 , L. A. Hark 1 , L.
Katz 1 .
1 Glaucoma, Wills Eye Hospital, Philadelphia,
PA; 2 Pharmacology and Experimental Therapeutics,
Thomas Jefferson University, Philadelphia, CA *CR
5558 — A0167 Foundation and Applications of the Universal EYE Exam Translator.
Samir I.
Sayegh. EYE Ctr Anterior- Vitreoretinal Surg, Eye
Center/The Retina Center, Champaign, IL
5559 — A0168 Tele-Ophthalmology Research in Post Phacoemulsification Diagnostic
Outcomes (TORPEDO) Study - Phase 1 and 2
Results.
Xiu Ling Tan 1, 2 , H. Wong 1, 2
Lim 1, 2 .
1
1, 2 , F. Yang , T.
Ophthalmology, Tan Tock Seng Hospital,
Singapore, Singapore; 2 National Healthcare Group
Eye Institute, Singapore, Singapore
5560 — A0169 Pilot Study Using Mobile
Health to Coordinate the Diabetic Patient,
Diabetologist and Ophthalmologist.
Irena Tsui 1 ,
A. Drexler 2 , A. Stanton 3 , J. Kageyama 1 , B. R.
Straatsma 1 . 1 Ophthalmology, JSEI, Los Angeles,
CA; 2 Endocrinology, UCLA, Los Angeles, CA;
3 Psychology, UCLA, Los Angeles, CA f
5561 — A0170 Association between government-insured general eye exams and incidence of self-reported glaucoma, cataracts and uncorrectable vision loss.
E. Badley 3, 2
Chan 3 .
1
, G. E. Trope 1
Yaping Jin
, Y. M. Buys 1
1, 2 ,
, C.
Ophthalmology & Vis Sci, University of
Toronto, Toronto, ON, Canada; 2 Dalla Lana School of Public Health, University of Toronto, Toronto,
ON, Canada;
ON, Canada
3 Arthritis Research and Evaluation
Unit, Toronto Western Research Institute, Toronto,
5562 — A0171 Low Utilization of Eye
Care Providers by Newfoundland and
Labrador Seniors: Barriers and Vision
Health Outcomes.
Kangping Cui 1 , G.
E. Trope 1, 2 , Y. M. Buys 1, 2 , C. Chan 2 , K.
Thavorn 3 , Y. Jin 1, 4 .
1 Ophthalmology and Vision
Siences, University of Toronto, Toronto, ON,
Canada; 2 Toronto Western Research Institute,
University Health Network, Toronto, ON,
Canada; 3 Keenan Research Centre, Li Ka Shing
Knowledge Institute, St. Michaels Hospital,
Toronto, ON, Canada; 4 Dalla Lana School of Public
Health, University of Toronto, Toronto, ON, Canada
5563 — A0172 : Inter-observer agreement and sensitivity - specificity analysis of a technology led, remote review glaucoma clinic.
Jonathan C.
Clarke , R.
Puertas, P.
J.
Foster , K.
Barton . NIHR
Biomedical Research Centre for Ophthalmology,
Moorfields Eye Hospital NHS Foundation Trust and
UCL Institute of Ophthalmology, London , United
Kingdom
5564 — A0173 Comparison of two diabetic retinopathy screening program models within a single primary care practice.
Kristina Holbrook ,
K.
Cotter , P.
A.
Yates.
Ophthalmology, University of Virginia , Charlottesville, VA *CR
5565 — A0174 Attitudes Toward Teleophthalmology.
Patricia Ple-plakon 1 , P. P.
Lee 1 , T. Blachley
Woodward 1 .
1
1 , D. C. Musch 1, 2 , M. A.
Ophthal & Visual Sciences, University of Michigan, Ann Arbor, MI; 2 Epidemiology,
University of Michigan, Ann Arbor, MI
5566 — A0175 Frequency of Gonioscopy and Pachymetry on First Visit Glaucoma
Patients.
Stephanie Ma 1 , S. Rana 1 , J. Tannir 2 , B.
Hughes 2 , A. Shukairy 2 , S. Nagori 2 , M. S. Juzych 2 ,
A. Goyal 2 .
1 Wayne State University School of
Medicine, Detroit, MI; 2 Ophthalmology, Kresge Eye
Institute, Detroit, MI f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
371

Thursday Posters 8:30 am – 10:15 am
5567 – 5588 – Thursday – Posters
5567 — A0176 An Analysis of Optometry
Referrals to Ophthalmology for Glaucoma
Suspects.
Catriona Barrett 1, 2 , C. J. O’Brien 2 ,
Optometry, Dublin Institute of J. Loughman 1
Technology, Dublin, Ireland;
Mater Misericordiae University Hospital, Dublin,
Ireland
.
1
2 Ophthalmology,
5568 — A0177 Comparison of eye disease diagnosis by optometrists and ophthalmologists in Ampang, Malaysia.
Duratul A.
Hussin
Carkeet 1 , P. Hendicott 1 , P. Baker 2
1 , A.
. 1 , A. Chen 3 of Optometry & Vision Science, Queensland
School
University of Technology, Kelvin Grove, QLD,
Australia; 2 School of Public Health & Social Work,
Queensland University of Technology, Kelvin
Grove, QLD, Australia; 3 Department of Optometry,
Universiti Teknologi MARA, Puncak Alam,
Malaysia
5569 — A0178 The Effectiveness of Vision
Screening for Visual Problems in School
Children.
Ellen Svarverud, T.
Langaas, H.
K.
Falkenberg . Dept of Optometry and Visual Science,
Buskerud and Vestfold University College,
Kongsberg, Norway
5570 — A0179 Outcomes of Large Sample
Vision Screening among School Children Aged
7-15 Years in Norway.
Helle K.
Falkenberg , T.
Langaas, E.
Svarverud.
Department of Optometry and Visual Science, Buskerud and Vestfold
University College, Kongsberg, Norway
5571 — A0180 National Burden of Eye Diseases in Iran 1990-2010; Findings from the Global
Burden of Disease Study 2010.
Elham Hatef
Naimi 1 , S. Mohammadi 2 , E. Ashrafi 2
Mohammadi 2 , F. Farzadfar 3 .
University, Baltimore, MD; 2
1
, C. Alinia
Medicine Residency Program, Johns Hopkins
2 , M.
General Preventive
Eye Research Center,
Farabi Eye Hospital, Tehran University of Medical
Sciences, Tehran, Islamic Republic of Iran; 3 Non-
Communicable Diseases Research Center, Tehran
University of Medical Sciences, Tehran, Islamic
Republic of Iran
5572 — A0181 Demographic and Clinical
Profile of a Homeless Population Presenting to an Ophthalmology Outreach Clinic.
Brian Stagg,
B.
Henriksen, M.
Padilla, B.
Radmall, E.
Liu, J.
Jensen , A.
Farukhi, J.
Pettey , A.
T.
Vitale . John A
Moran Eye Center , Salt Lake City , UT
5573 — A0182 Stakeholder Perceptions and Practices Regarding the Ocular Effects of Hyperbaric Oxygen Therapy.
Arjun J.
Dirghang i
Lehman 1 . 1
1 , B. K. Lee 2 , A. Allan 4 , K. Gandhi 3 , A. Y.
Department of Ophthalmology, Drexel
University College of Medicine, Philadelphia,
PA; 2 Department of Epidemiology and Biostatistics,
Drexel University School of Public Health,
Philadelphia, PA; 3 Drexel University College of
Medicine, Philadelphia, PA; 4 Drexel University
School of Health Professions, Philadelphia, PA
5574 — A0183 Positioning-Related Ocular
Complications of Minimally-Invasive Radical
Prostatectomies.
Frank S.
Siring o
C. Diebert 3 , B. Spencer 3, 4 .
1
1, 2 , T. Wen 4
Ophthalmology,
University of Colorado School of Medicine,
,
Denver, CO; 2 Ophthalmology, Columbia
University College of Physicians and Surgeons,
New York, NY; 3 Urology, Columbia University
College of Physicians and Surgeons, New York,
NY; 4 Epidemiology, Columbia University Mailman
School of Public Health, New York, NY
5575 — A0184 Morbidity and Mortality
Conference Using an Anonymous Audience
Response System to Address Core Competencies in Ophthalmology.
Jessica Prince 1 , L. A. Eisen 2 , J.
B. Rosenberg 1 . 1 Ophthalmology, Montefiore Med
Ctr/Albert Einstein, Bronx, NY; 2 Critical Care,
Montefiore Med Ctr/Albert Einstein, Bronx, NY
5576 — A0185 Determinants of hospitalization after cataract surgery in a large managedcare United States population.
Sophia Y.
Wang
Stein 1
1, 2 , T. Blachley 1 , J. Ayanian 3 , P. P. Lee 1 , J. D.
Department of Ophthalmology and Visual .
1
Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; 2 Department of
Ophthalmology, University of California, San
Francisco, San Francisco, CA;
Boston, MA
3 Department of
Health Care Policy, Harvard Medical School,
5577 — A0186 Training on the Prevention of Surgical Errors in Ophthalmology: the
Resident Perspective.
Allison Chen , A.
Havnaer,
P.
B.
Greenberg.
Alpert Medical School of Brown
University , Providence , RI
5578 — A0187 Improving the Transition to
Ophthalmology Residency: A Survey of First-
Year Ophthalmology Residents.
Travis Redd
A. Thomas 2 , T. S. Hwang 2 . 1
1
Oregon Health & Science University, Portland,
,
School of Medicine,
OR; 2 Ophthalmology, Casey Eye Institute, Oregon
Health & Science University, Portland, OR
5579 — A0188 Mindfulness Training to
Increase Resilience and Decrease Stress and
Burnout in Ophthalmology Residents: a
Pilot Study.
Jullia A.
Rosdah l 1 , K. Kingsolver 2 .
1 Ophthalmology, Duke University, Durham, NC;
2 Family Medicine, Duke University, Durham, NC
5580 — A0189 Breaking Bad News:
Evaluating the Impact of a Multidisciplinary
Training Program for Ophthalmology
Residents.
Sarah M.
Hilker t 1, 2 , S. G. Jain
1
1 , C.
, J. Boyer 1 , M. Cebulla 1 , S. A. Pfeil
S. L. Robbins 2 . 1
1 , S. C. Benes
Ophthalmology, Havener Eye
Institute, the Ohio State University, Columbus, OH;
2 Ophthalmology, Ratner Children’s Eye Center,
University of California, San Diego, San Diego, CA
5581 — A0190 Gender trends and practice differences of Canadian ophthalmologists.
Yvonne M.
Buys 1
McAlister 1
Marchais 3 .
1
, Y. Jin 1, 2 , R. Braga-Mele 1
, C.
, B. Des
Ophthalmology & Vision Sciences,
University of Toronto, Toronto, ON, Canada; 2 Dalla
Lana School of Public Health, University of
Toronto, Toronto, ON, Canada; 3 Médecine-Dép. d,
Université Lava, Quebec City, QC, Canada
5582 — A0191 A systematic review and costeffectiveness analysis of disinfection methods for Goldmann Applanation Tonometry.
Omar
Akhtar 1, 2 , H. Singh 1, 2 , W. Hodge 1, 2 .
1 Ophthalmology,
Western University, London, ON, Canada;
2 Epidemiology and Biostatistics, Western
University, London, ON, Canada
5583 — A0192 Evaluating surgical efficiency in the transition from the Accurus to the
Constellation Vision System for microincisional vitrectomy surgery (MIVS) from an operations management perspective.
G. Murray
FL; 2
1, 2 . 1
Daniel Gologorsky 1 , T.
Bascom Palmer Eye Institute, Miami,
Murray Ocular Oncology & Retina, Miami, FL
5584 — A0193 The Effect of Requiring Patientspecific Prescriptions on the Utilization of
Intravitreal Bevacizumab.
Alexander G.
Miller , L.
Rao, D.
Y.
Rowland, J.
Hornik . Retina Associates of
Cleveland, Beachwood, OH
5585 — A0194 Use of Statistical Analyses in the
Ophthalmic Literature.
Renato Lisboa, D. Meira-
Freitas, A. J. Tatham, A. Marvasti, L. Sharpsten, F.
A. Medeiros. Ophthalmology, Hamilton Glaucoma
Center, La Jolla, CA *CR
5586 — A0195 Comparing Quality
Performance Measures Publicly Reported by Ophthalmic Organizations.
Monica M.
Michelotti
D. W. Flanagan 2
Hingorani 2
MI; 2
Kingdom; 3
1 , J. S. Weizer
. 1
Moorfields Eye Hospital, London, United
Sweden; 4
Kingdom *CR
1 , J. D. Stein 1
, A. C. Odergren 3
, S. P. Kelly 4
, P. P. Lee 1 , M.
University of Michigan, Ann Arbor,
St Erik’s Eye Institute, Stockholm,
Royal Bolton Hospital, Bolton, United
,
5587 — A0196 Quality Measures Within a
Group Retina Practice - Cultural Shift and
Clinical Outcomes.
Brian Joondeph . Colorado
Retina Associates , Denver , CO
5588 — A0197 Assessing the development of guidelines for primary open angle glaucoma using the AGREE II instrument.
Todd H.
Driver
P. P. Lee 2 , Y. Ou 3 . 1 Medical School, University of California, San Francisco, San Francisco, CA;
3
2 Department of Ophthalmology, University of
Michigan Kellogg Eye Center, Ann Arbor, MI;
Department of Ophthalmology, University of
California, San Francisco, San Francisco, CA *CR
1 ,
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
372

Thursday – Posters – 5589 – 5608
5589 — A0198 Time Motion Study of
Electronic Health Record (EHR) Documentation
Time in Ophthalmology Exams.
Michelle Hribar 1
S. Read-Brown
Yackel 1
2 , M. Pasha
, M. F. Chiang 2, 1
1, 2 , L. Reznick 2 , T.
Medical Informatics
,
.
1 and Clinical Epidemiology, Oregon Health and
Science University, Portland, OR; 2 Ophthalmology,
Case Eye Institute, Oregon Health and Science
University, Portland, OR
5590 — A0199 Comparing iPhone and
Android Smartphone Application Development in Ophthalmology Using the Ocular Trauma
Score Application as a Prototype.
Emily Su 1 ,
K. Vinod 1 , S. Luong 2 , O. B. Ozgur 3 , P. Latkany 1 ,
O. Ozgur 1 .
1 Ophthalmology, The New York Eye and Ear Infirmary, New York, NY; 2 University of
California, Irvine, Irvine, CA; 3 Irvine High School,
Irvine, CA
5591 — A0200 Feasibility of using OpenEyes to identify potentially eligible patients for clinical research.
Annelie Small, B.
Aylward, R.
Khan , C.
E.
Pavesio, M.
Pefkianaki , P.
J.
Patel.
NIHR Moorfields Biomedical Research Centre ,
Moorfields Eye Hospital NHS Foundation Trust and
UCL Institute of Ophthalmology, London , United
Kingdom
5592 — A0201 Accuracy of the International
Classification of Diseases, 9th Revision (ICD-9) as a research tool for the identification of patients with polymyalgia rheumatica and concurrent noninfectious uveitis.
Eduardo Uchiyama 1 , S.
Faez 1 , H. Nasir 1 , S. H. Unizony 2 , G. N. Papaliodis 1 ,
L. Sobrin 1 .
1 Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA; 2 Rheumatology,
Massachusetts General Hospital, Boston, MA
5593 — A0202 Uses of the Word “Macula” in Written English, 1400-Present.
Stephen G.
Schwartz 1 , C. T. Leffler 2 . 1 Bascom Palmer Eye
Institute, Univ of Miami Miller Sch of Med, Naples,
FL; 2 Ophthalmology, Virginia Commonwealth
University, Richmond, VA *CR
5594 — A0203 Cost Effectiveness of Anti-
Oxidant Vitamin + Zinc Treatment to Prevent the Progression of Intermediate Dry AMD to its Wet Form. A Singapore Perspective.
Shao
Onn Yong 1 , N. Saxena 2 , P. P. George 2 , B. Heng 2 , T.
Lim 1 .
1 Ophthalmology, Tan Tock Seng Hospital,
Singapore, Singapore; 2 Health Services and
Outcomes Research, National Healthcare Group,
Singapore, Singapore *CR
5595 — A0204 Cost-effectiveness Analysis of iStent and Phacoemulsification versus
Glaucoma Medications in the Ontario Health
Insurance Plan (OHIP).
M. Hutnik 1
Yiannis Iordanous
, M. Malvankar 1, 2 .
1
1 , C.
Ophthalmology,
University of Western Ontario, London, ON,
Canada; 2 Epidemiology and Biostatistics, University of Western Ontario, London, ON, Canada
5596 — A0205 Treatment Patterns and
Associated Costs of Anti-VEGF Therapy for Neovascular Age-Related Macular
Degeneration.
Szilard Kiss 1
Wilson 3 , A. Huang
Johnston 3
3
, A. Turpcu 4 . 1
, P. U. Dugel
, D. Smith
Cornell Medical College, New York, NY; 2
Consultants of Arizona, Phoenix, AZ; 3
Genentech, Inc.,
South San Francisco, CA *CR
3 , H. Varker
Health Analytics, Bethesda, MD; 4
2
3
, K.
, S. S.
Ophthalmology, Weill
Retina
Truven
Exhibit/Poster Hall SA A0236-A0246
Thursday, May 08, 2014 8:30 AM-10:15 AM
Visual Psychophysics / Physiological Optics
Moderator: Allison M. McKendrick
5597 — A0236 Comparison of the electronic versions of Ishihara pseudochromatic plates with the printed version.
Jeung Kim, T.
Gaasch , A.
Shum . Southern College of Optometry, Memphis,
TN
5598 — A0237 Reliability of Smartphone-
Based Electronic Visual Acuity Testing:
(Applications in Remote Monitoring and Clinical Research of Macular
Pathology).
Seung-Young Yu 1 , J. Yang 1 , Y. Kim 1 ,
H. Kwak 2 .
1 1 , M. Blumenkranz Ophthalmology,
Kyung Hee University, Seoul, Republic of
Korea; 2 Ophthalmology, Stanford University School of Medicine, Stanford, CA f
5599 — A0238 Evaluation of Tablet
Computers in the Assessment of Visual
Acuity: Can iPads™ Replace the Snellen
Chart?.
Conor P. Malone 1, 2
Al Daqqaq 3, 1 , C. Murphy 1, 2
, C. McCourt 1
.
1
Royal College of Surgeons in Ireland, Dublin,
Ireland; 2
, N. T.
Ophthalmology,
Ophthalmology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland;
Busaiteen, Bahrain
3 RCSI-MUB,
5600 — A0239 PsyPad: an iPad application to enable vision research.
Allison M.
McKendrick 1 ,
D. J. Lawson 2 , A. Turpin 2 . 1 Optometry & Vision
Sciences, University of Melbourne, Parkville, VIC,
Australia;
Australia
2 Computing and Information Systems,
The University of Melbourne, Parkville, VIC,
5601 — A0240 Implementing the MNREAD
Reading Acuity Test on an iPad3.
Aurelie
Calabrese
Legge 1 .
1
1 , S. Gamam 1 , J. Mansfield 2 , G. E.
Psychology, University of Minnesota,
Minneapolis, MN;
NY *CR
2 Psychology, State University of New York College at Plattsburgh, Plattsburgh,
5602 — A0241 Compliance and Test
Variability of Patients with Maculopathy in
Using an iPhone-Based Shape Discrimination
Hyperacuity Test at Home.
Yi-Zhong
Wang 1, 2
Bartlett 4
, Y. He 2
.
1 Retina Foundation of the Southwest,
Dallas, TX; 2
, G. Mitzel 1 , S. Zhang 3 , M. B.
Ophthalmology, UT Southwestern
Medical Center, Dallas, TX; 3 Clinical Sciences, UT
Southwestern Medical Center, Dallas, TX; 4 Vital Art and Science Incorporated, Richardson, TX *CR
5603 — A0242 Self assisted Online visual testing,.
Norbert Schrage 1, 2 , F. Simonsen 2 , C.
Dudziak 2 , M. Dutescu 3 .
1 Ophthalmology, City
Hospital Cologne, Cologne, Germany; 2 ACTO e.V., Aachen, Germany; 3 Ophthalmology, RWTH
Aachen, Aachen, Germany
5604 — A0243 Home vision auto-testing in patients with AMD using an iPad App.
Matthias
G.
Hartmann . Private Practice , Berlin ,
Germany *CR
5605 — A0244 Effects of age and blur on, and test-retest variability of, a handheld radial shape deformation test.
Paul C. Knox 1 ,
A. O’Connor 1, 2 , A. F. Milling 1, 3 .
1 Eye and Vision
Science, University of Liverpool, Liverpool, United
Kingdom; 2 Orthoptics, University of Liverpool,
Liverpool, United Kingdom; 3 Orthoptics, Stepping
Hill Hospital, Manchester, United Kingdom *CR
5606 — A0245 A Novel Way to Assess
Visual Performance in Elite Athletes.
David
Kirschen 1 , D. M. Laby 2 , D. Meadows 3 .
1 Vision
Science and Optometry, Southern California
2
College of Optometry, Fullerton, CA;
Ophthalmology, Harvard Medical School, Boston,
MA; 3 Ophthalmology, University of Florida,
Gainsville, FL *CR
5607 — A0246 A Robust Method for Assessing
Visual Performance Ability in Amateur Baseball
Players.
David Meadows 1 , D. Kirschen 2 , D.
M. Laby 3 .
1 University of Florida, Gainesville,
FL; 2 Vision Science and Optometry, Southern
California College of Optometry, Fullerton, CA;
3 Ophthalmology, Harvard Medical School, Boston,
MA *CR
Exhibit/Poster Hall SA A0256-A0296
Thursday, May 08, 2014 8:30 AM-10:15 AM
Glaucoma
Moderator: Ki Ho Park
5608 — A0256 The Flashing Light-
Induced Pupil Response (FLIPR) Glaucoma
Study.
Patrick Shorte r 1 , D. Eren 2 , S. G. Jain 2 , A. T.
Hartwick 1 . 1 College of Optometry, The Ohio State
University, Columbus, OH; 2 Havener Eye Institute,
The Ohio State University, Columbus, OH f f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
373

Thursday Posters 8:30 am – 10:15 am
5609 – 5628 – Thursday – Posters
5609 — A0257 Evaluation of Steady State
Pattern Electroretinography (ssPERG) in
Discriminating Normal from Glaucoma Suspect and Glaucomatous Eyes.
Tello 1, 2 , P. H. Derr
, R. Ritch
3
1, 2
Carlos
, P. Seshadri 1
Urgile
, J. M. Liebmann 1, 4 . 1 s 1 , C.
, A. O. Gonzalez
Garcia 3 Einhorn
Clinical Research Center, New York Eye and
Ear Infirmary, New York, NY; 2 Department of
Ophthalmology, New York Medical College,
Valhalla, NY;
Brook, NJ;
NY *CR
4
3 Engineering, Diopsys Inc, Pine
NYU School of Medicine, New York,
5610 — A0258 Factors predicting the rate of visual field progression in normal-tension glaucoma eyes with tilted disc.
Youngkyo
Kwun 1, 2 , G. Han 1 , Y. Choy 1 , C. Kee 1, 2 .
1 Department of Ophthalmology, Samsung Medical Center,
Seoul, Republic of Korea; 2 School of medicine,
Sungkyunkwan University, Seoul, Republic of
Korea
5611 — A0259 User Friendly Tool Using
Kalman Filter Algorithms to Display Glaucoma
Progression Indicators and Personalized Time to Next Test.
Mariel S.
Lavier i 1 ,
M. Li
E. Helm
Stein 4
1 , G. Schell
3 , M. Van Oyen 1
, S. Devaprasad
1 , P. Martinez Villarreal 2
1
, D. C. Musch 4
, J.
, J. D.
. 1 Department of Industrial and Operations
Engineering, University of Michigan, Ann Arbor,
MI;
TX;
2 The University of Texas at El Paso, El Paso,
3 Kelley School of Business, Indiana University,
Bloomington, IN; 4
Arbor, MI *CR
Department of Ophthalmology
& Visual Sciences, University of Michigan, Ann
5612 — A0260 A Comparison of Learning
Effects for Standard Automated Perimetry,
Short-wavelength Automated Perimetry and
Frequency-Doubling Technology Perimetry in
Healthy Subjects.
Lorraine Myers, R.
Hu , L.
S.
Morgan , J.
S.
Hoop , L.
Racette.
Department of
Ophthalmology, Indiana University , Indianapolis ,
IN
5613 — A0261 The Melanopsin, Cone and
Rod Components of the Pupil Light Reflex and
Color Discrimination in Glaucomatous Optic
Neuropathy.
Gloria L.
Duque-Chica
Gracitelli
Costa 1, 2
3 , A. A. Moura
, A. Paranhos Jr.
Paulo, Brazil; 2
1, 2
3
1, 2 , C. P.
, B. V. Nagy 1, 4
, D. F. Ventura 1, 2
, M. F.
. 1 Instituto de Psicologia, Universidade de São Paulo, São
Núcleo de Apoio à Pesquisa em
Neurociência Aplicada (NAPNA), Universidade de São Paulo, São Paulo, Brazil;
Oftalmologia, Universidade Federal de São Paulo,
São Paulo, Brazil; 4
3 Departamento de
Department of Mechatronics,
Optics and Engineering Informatics, University of
Technology and Economics, Budapest, Hungary
5614 — A0262 A Novel Simulation Tool for the
Evaluation of Perimetric Algorithms: Benefits of Using Prior Data at Test Onset.
Emmanouil
Tsamis , D.
B.
Henson . Manchester Biomedical
Research Centre , University of Manchester ,
Manchester , United Kingdom *CR
5615 — A0263 Comparison of intra-eye and inter-eye visual field asymmetry score in nonglaucoma subjects with early stage of Primary
Open Angle Glaucoma (POAG) patients. Naqibah
, D. B. Henson 1, 2 , T. Aslam 2, 1 . 1 Ghazali 1, 2 School of
Medicine, University of Manchester, Manchester,
United Kingdom;
United Kingdom
2 Research Department,
Manchester Royal Eye Hospital, Manchester,
5616 — A0264 Does Stimulus Size Affect Test-
Retest Reliability for Peripheral Visual Field
Testing?.
Tamara L.
Berezina , C.
Kuriakose, A.
S.
Khouri , A.
M.
Kolomeyer, R.
D.
Fechtner . Institute of Ophthalmology and Visual Science, Rutgers -
New Jersey Medical School , Newark , NJ
5617 — A0265 Progression of visual field in patients with primary open-angle glaucoma: The Study PROG-F 2 . Levels of progression.
Jean-Marie Giraud 1, 2 , F. Aptel 3 , H.
El Chehab
Valero 1
2 , N. Aryal-Charles
, R. Sekfali 1
3 , M. Delbarre
, M. Bourniquel 1
1 , B.
, R. Vignal
J. G. Renard 2 .
1 Ophthalmology, Sainte Anne
Military Hospital, Toulon, France; 2 Ophthalmology,
Val de Grâce Military Hospital, Paris,
France; 3 Ophthalmology, Grenoble University
Hospital, Grenoble, France
1 ,
5618 — A0266 Progression of visual field in patients with ocular hypertension and primary open-angle glaucoma:PROG-F study1 Preliminary results.
Jean-Paul G.
Renard 1 , J. Giraud 1 , N. Aryal-Charles 2 , H. El
Chehab 1 , F. May 1 , C. Chiquet 2 , J. Romanet 2 , F.
Aptel 2 .
1 Ophtalmologie, Hopital du Val de Grâce,
Paris, France; 2 Ophtalmologie, CHU Grenoble,
Grenoble, France
5619 — A0267 Predicting progressive glaucomatous optic neuropathy using random forests based on longitudinally collected standard automated perimetry data.
Lucie
Sharpsten
Johnson 4
1 , J. Fan 2 , S. Demirel
, R. A. Levine 2 .
1
3 , X. Su of California, San Diego, La Jolla, CA;
5
2
, C. A.
Hamilton Glaucoma
Center, Department of Ophthalmology, University
Department of Mathematics and Statistics, San Diego State
University, San Diego, CA; 3 Devers Eye Institute,
Legacy Health System, Portland, OR; 4 Department of Ophthalmology and Visual Sciences,
University of Iowa, Iowa City, IA;
Paso, El Paso, TX
5 Department of
Mathematical Sciences, University of Texas at El
5620 — A0268 Effect of a novel computer software simulating Humphrey Visual Field
(HVF) on patient performance of HVF.
Mayank
Bansal , T.
Arora, T.
Dada . Ophthalmology, All India
Institute of Medical Sciences , New Delhi, India
5621 — A0269 Eye Movements Alterations
During Reading Process in Patients with
Glaucoma: a Microperimeter Study.
Angelica
Cerulli 1, 2 , L. Cerulli
R. Mancino 1
1 , M. Cesareo 1
, C. Mirisola 2
, E. Ciuffoletti
, C. Nucci 1 .
1
1 ,
Experimental
Medicine And Surgery, University Of Rome Tor
Vergata, Rome, Italy; 2 National Institute For Health,
Migration And Poverty, Rome, Italy
5622 — A0270 Simfield: A computer simulated visual field test to screen for glaucoma.
Justin
Hellman 1 , M. E. Perrone
Farrokh-Siar 3
1 , D. Altamirano
, A. Anchala 4 .
1
2 , L.
Pritzker
Chicago, IL;
, S. Ksiazek 5
School of Medicine, University of Chicago,
2 Universidad Andrés Bello, Santiago,
Weiss Hospital, Chicago, IL; 4 Chile; 3 Department of
Ophthalmology, Northwestern University, Chicago,
IL; 5 Section of Ophthalmology and Visual Science,
Department of Surgery, University of Chicago,
Chicago, IL
5623 — A0271 Open-Angle Glaucoma: BCEA and retinal sensitivity compared to Visual Field and RNFL.
Daniela Domanico , F.
Verboschi, C.
Di
Crescenzo, M.
Salomone , L.
Spadea , E.
M.
Vingolo.
Sapienza , University of Rome , Polo Pontino,
Latina , Ital y
5624 — A0272 Functional parameters in patients with ocular hypertension and primary open-angle glaucoma.
Mariella Salomone , F.
Verboschi, S.
Fragiotta, S.
Valente, D.
Domanico , L.
Spadea , E.
M.
Vingolo.
ophtalmology, University of
Rome “La Sapienza”, Terracina, Italy
5625 — A0273 Enhancement Of Visual Field
Sensitivity In Glaucomatous Eyes Following
Surgical Intraocular Pressure Reduction.
Tracy
M. Wright 1 , I. Goharian 1 , S. K. Gardiner 2 , D.
S. Greenfield 1 , M. Sehi 1 .
1 Bascom Palmer Eye
Institute, University of Miami Health, Palm Beach
Gardens, FL; 2 Devers Eye Institute, Legacy Health,
Portland, OR f
5626 — A0274 Cataract surgery slows the slow component of visual field decay but not the fast component in glaucoma patients.
Jiwoong Lee
E. Morales
CA; 2
1 , F. Yu
Nouri-Mahdavi 1
1, 3 , A. Afifi
, J. Caprioli 1
3 , N. Abdollahi
.
1
1 , K.
Ophthalmology,
Jules Stein Eye Institute, UCLA, Los Angeles,
Ophthalmology, Pusan National University
School of Medicine, Busan, Republic of
Korea; 3 Biostatistics, UCLA School of Public
Health, Los Angeles, CA
1, 2 ,
5627 — A0275 Longitudinal changes in visual field sensitivity compared to estimates of retinal ganglion cell loss in glaucoma.
Michelle Sato 1, 2 , A.
J. Tatham 2, 1 , L. M. Zangwill 2, 1 , A. R. Spitze 1, 2 , R.
N. Weinreb 1, 2 , F. A. Medeiros 1, 2 . 1 Ophthalmology,
University of California, San Diego, La Jolla,
CA; 2 Glaucoma, Hamilton Glaucoma Center and Department of Ophthalmology, La Jolla,
CA *CR , f
5628 — A0276 More accurate modelling of visual field progression in glaucoma:
ANSWERS.
Haogang Zhu 1, 2 , D. P. Crabb 1 , D.
School of Health Sciences, F. Garway-Heath 2
City University London, London, United
Kingdom; 2
.
1
Institute of Ophthalmology, University
College London, London, United Kingdom *CR , f
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
374

Thursday – Posters – 5629 – 5648
5629 — A0277 A Comparison of the Prevalence of Defects in the Superior versus Inferior
Visual Field: Evidence for a Model with Diffuse
Shallow as Well as Deep Local Damage.
Donald
, M. Chen 2 , A. S. Raza 2 C. Hood 1
G. V. De Moraes 3, 5 , R. Ritch 3 .
1
, P. Alhadeff 3, 4
Psychology and
,
Ophthalmology, Columbia University, New York,
NY; 2 Psychology, Columbia University, New
York, NY; 3 Ophthalmology, New York Eye and
Ear Infirmary, New York, NY; 4 Ophthalmology,
Hospital Servidor Publico Estadual, San Paulo,
Brazil; 5 Ophthalmology, New York University
Medical Center, New York, NY *CR
5630 — A0278 An Investigation of the Spatial
Weighting Procedure Used in the Visual
Field Index.
Megan Tuoh y 1 , B. C. Samuels 2 ,
L. Racette 1 . 1 Eugene and Marilyn Glick Eye
Institute, Indiana University School of Medicine,
Indianapolis, IN; 2 Department of Ophthalmology,
University of Alabama at Birmingham,
Brimingham, AL f
5631 — A0279 Censoring sensitivities results in a non-linear model of sensitivity vs. variability for standard automated perimetry.
Deborah
Goren 1 , W. H. Swanson
Gardiner 1
2 , S. Demirel
.
1
Devers Eye Institute, Portland, OR; 2
1 , S. K.
Discoveries in Sight Laboratories,
School of
Optometry, Indiana University, Bloomington, IN
5632 — A0280 Evaluation of visual function in ocular hypertension: PROG-F3 study.
Maxime
Delbarre 1 , J. Giraud 3 , F. Aptel 2 , H. El Chehab 1 , J.
Fenolland 1 , M. Maréchal 1 , A. Marill 1 , F. May 1 , J. G.
Renard 1 .
1 Department of Ophthalmology, Military
Hospital of Val-de-Grace, Paris, France; 2 CHU
Grenoble, Grenoble, France; 3 HIA Saint-Anne,
Toulon, France
5633 — A0281 Comparison of global visual field indices (MD,VFI), GPA II change and cluster analysis of visual field progression in glaucoma.
Valeria Bono
M. Normando 1, 2
Salvatore 3
, L. Crawley 2
, P. Bloom 2
1, 3 , B. M. Davis 1
, F. Ahmed
, M. Cordeiro 1, 2 .
1
2
, E.
, C.
UCL
Institute of Ophtalmology, London, United
Kingdom; 2 Glaucoma unit, Western Eye Hospital,
London, United Kingdom; 3 Experimental
Biomedicine and Clinical Neuroscience,
Ophthalmology Section, University of Palermo,
Palermo, Italy
5634 — A0282 Reliability Indices and Rates of Visual Field Change in Glaucoma.
Gustavo
V. De Moraes 1, 2 , J. M. Liebmann 1, 2 , R. Ritch 2 ,
T. Krupin 3 .
1 Ophthalmology, New York Univ
School of Med, New York, NY; 2 Ophthalmology,
New York Eye & Ear Infirmary, NEW YORK,
NY; 3 Ophthalmology, Northwestern University,
Chicago, IL *CR , f
5635 — A0283 Monte-Carlo Simulations for
Separate Estimation of Detection and Reaction
Times to Low-Contrast Peripheral Stimuli while
Car Following in Glaucoma Patients.
Felipe A.
Medeiros , P.
Rosen, A.
Marvasti , R.
N.
Weinreb, E.
R.
Boer . Ophthalmology, Univ of California San
Diego, La Jolla, CA
5636 — A0284 Effectiveness Of Achieving
Single Digit Iop Targets With Filtration Surgery
On Decreasing Global And Localized Visual
Field Progression In Eyes With Progressive
Normal-Tension Glaucoma.
Shawn M.
Iverson 1
1 , W. J. Feuer 1
,
S. K. Schultz
Greenfield 1 .
1
2 , W. Shi , D. S.
Ophthalmology, Bascom Palmer
Eye Institute - University of Miami, Palm Beach
Gardens, FL; 2 Ophthalmology, Bishop Eye
Associates, Hilton Head Island, SC
5637 — A0285 Detecting vision loss in glaucoma using eye movement scanpaths recorded during free viewing of movies - a proof of principle study.
Nicholas D.
Smith, H.
Zhu,
D.
P.
Crabb.
Optometry and Visual Science, City
University London , London , United Kingdom
5638 — A0286 Baseline Visual Field Damage as a Predictor of Faster Rates of Visual Field
Progression in the Low-pressure Glaucoma
Treatment Study.
Moraes 2, 1
Krupin 5, 6
Ritch 2, 8 .
1
Jessica E. Chan
, R. N. Weinreb 3
, S. K. Gardiner 7
1 , G. V. De
, D. S. Greenfield
, J. M. Liebmann
School of Medicine, New York, NY; 2
4
2, 1
, T.
, R.
Ophthalmology, New York University
Einhorn
Clinical Research Center, New York Eye and Ear
Infirmary, New York, NY; 3 Hamilton Glaucoma
Center, University of California at San Diego,
4 Ophthalmology, Bascom San Diego, CA;
Palmer Eye Institute, University of Miami Miller
School of Medicine, Palm Beach Gardens,
FL; 5 Ophthalmology, Feinberg School of Medicine,
Northwestern University, Chicago, IL; 6 The
Chicago Center for Vision Research, Chicago,
IL; 7
OR; 8
Devers Eye Institute, Legacy Health, Portland,
Ophthalmology, New York Medical College,
Valhalla, NY *CR
5639 — A0287 Patient Perception of
Glaucomatous Visual Field Loss Associated with Disease Severity.
Kenji Fujitani 1, 2 , S. Park 1, 3 ,
D. Su 1 , J. L. Simonson 1 , C. C. Teng 1, 3 , J. M.
Liebmann 1, 4 , R. Ritch 1, 3 .
1 Moise and Chella Safra
Advanced Ocular Imaging Laboratory, New York
Eye and Ear Infirmary of the Mount Sinai Health
System, New York, NY; 2 Icahn School of Medicine at Mount Sinai, New York, NY; 3 Department of
Ophthalmology, New York Medical College,
Valhalla, NY; 4 Department of Ophthalmology, New
York University School of Medicine, New York,
NY *CR
5640 — A0288 The Effect of Stimulus Size on the Effective Dynamic Range of Perimetry.
Stuart
K. Gardiner
Swanson 1
1 , S. Demirel 1 , D. Goren
2 .
Devers Eye Institute, Portland, OR; 2
1 , W. H.
Discoveries In Sight Laboratories,
School of
Optometry, Indiana University, Bloomington, IN
5641 — A0289 A New Visual Field Testing
Algorithm that Better Detects Glaucomatous
Progression.
Andrew Turpin 1 , L. X. Chong 2, 1 , A.
M. McKendrick 2 .
1 Computing and Information
Systems, University of Melbourne, Melbourne,
VIC, Australia; 2 Department of Optometry and
Vision Sciences, University of Melbourne,
Melbourne, VIC, Australia *CR
5642 — A0290 Effect of Panretinal
Photocoagulation for Diabetic Retinopathy on Retinal Nerve Fiber Layer and Visual
Field.
Peng Lei, J. T. Whitson. University of Texas
Southwestern, Dallas, TX *CR
5643 — A0291 Evaluating Sources of Testretest Variablity in Glaucomatous Visual Field
Defects.
William H.
Swanson 1 , M. W. Dul 2 , D. G.
Horner 1 , V. E. Malinovsky 1 . 1 School of Optometry,
Indiana University, Bloomington, IN; 2 SUNY
College of Optometry, New York, NY
5644 — A0292 Using High-Density Perimetry to Test a Model of Glaucomatous Damage of the Macula and to Assess the Placement of
Visual Field Test Points.
Alyssa C. Ehrlich
M. Nguyen 2 , A. S. Raza 3 , I. Sliesoraityte
, D. C. Hood 1, 7
4
1 ,
, A.
Psychology, Mast
GA;
5
3
, U. Schiefer 5, 6 .
1
Columbia University, New York, NY; 2
Neurobiology and Behavior, Columbia
University, New York, NY; 4
Internal
Medicine, Morehouse School of Medicine, Atlanta,
Tuebingen, Germany; 6
Institut de la Vision,
INSERM CIC 503, Paris, France; 5 Centre for
Ophthalmology, University of Tuebingen,
Competence Centre “Vision
Research”, University of Applied Sciences, Aalen,
Germany; 7 Ophthalmology, Columbia University,
New York, NY *CR
5645 — A0293 A Mobile Platform for
Evaluation of Processing Speed and Divided
Attention at Varying Contrast Levels in
Glaucoma Patients.
Peter Rosen, A.
Marvasti ,
E.
R.
Boer , M.
Della Penna, R.
N.
Weinreb, L.
M.
Zangwill , A.
Silverman, F.
A.
Medeiros .
Department of Ophthalmology, University of
California San Diego, San Diego, CA
5646 — A0294 A Novel Paradigm for
Vision Functionometry in Glaucoma.
Makoto
Miyakoshi
Medeiros 2
1
.
1
, S. Makeig 1 , A. J. Tatham 2 , F. A.
Swartz Center for Computational
Neuroscience, Institute for Neural Computation,
University of California San Diego, La Jolla, CA;
2 Department of Ophthalmology, University of
California San Diego, La Jolla, CA
5647 — A0295 The Ocular Hypertension
Treatment Study (OHTS): Longitudinal analyses of mean deviation (MD) loss and its association with visual acuity (VA) and contrast sensitivity
(CS) in eyes newly diagnosed with primary-open angle glaucoma (POAG).
Mae O. Gordon 1, 2 , J.
Miller 2 , J. Beiser 1 , M. A. Kass 1 , F. Gao 2 .
1 Ophthal
& Vis Sciences, Washington Univ Sch of Med, St
Louis, MO; 2 Division of Biostatistics, Washington
University School of Medicine, St Louis, MO f
5648 — A0296 The relationship between frequency doubling technology (FDT) perimetry and useful field of view (UFOV) testing in glaucoma.
Arielle R.
Spitze , A.
J.
Tatham , P.
Rosen, L.
M.
Zangwill , R.
N.
Weinreb, M.
A.
Sato ,
E.
R.
Boer , F.
A.
Medeiros . Hamilton Glaucoma
Center , Department of Ophthalmology, University of California , San Diego, La Jolla, CA *CR, f f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
375

Thursday Posters 8:30 am – 10:15 am
5693 – 5715 – Thursday – Posters
Glaucoma
See Monday Posters, 5649 - 5692, 8:30-10:15am.
Exhibit/Poster Hall SA B0001-B0028
Thursday, May 08, 2014 8:30 AM-10:15 AM
Biochemistry/Molecular Biology
Moderators: Qiong Ding and Eranga N. Vithana
5693 — B0001 Molecular and Cellular
Changes of Scleral Fibroblasts after Exposure to Experimental Glaucoma in Mice.
Ericka
Oglesby 1
Steinhart 1
, G. Tezel 2 , E. Cone-Kimball
, J. Jefferys 1 , M. Pease 1
1 , M. R.
, H. Quigley
1 Ophthalmology, Johns Hopkins School of
1 .
Medicine, Baltimore, MD; 2 Department of
Ophthalmology & Visual Sciences, University of
Louisville School of Medicine, Louisville, KY
5694 — B0002 Differences in cholesterol species of aqueous humor in ocular normotensive and hypertensive DBA/2J mice.
Katyayini Aribindi ,
Y.
S.
Guerra , H.
M.
Stradecki, S.
K.
Bhattacharya .
Bascom Palmer Eye Institute, University of Miami
School of Medicine , Miami, FL
5695 — B0003 Differences in aqueous humor phospholipid profiles of DBA/2J mice in ocular normotensive and hypertensive state.
HAIYAN
WANG
.
1
2 , G. Edwards 2 , S. K.
Shanghai First People, Shanghai,
China; 2
2, 1 , Y. S. Guerra
Bhattacharya 2
Bascom Palmer Eye Institute, Miami, FL
5696 — B0004 Correlative analysis of clinical findings, autoimmune characteristics and complement activation in human glaucomatous eyes.
Oliver W. Gramlich 1 , A. C.
Cook 2
Kuehn
, S. Beck
2
1 , N. Pfeiffer 1 , F. H. Grus 1 , M. H.
.
1 Experimental Ophthalmology, Department of Ophthalmology, University Medical Center
Mainz, Mainz, Germany; 2 Glaucoma Cell Biology
Laboratory, Department of Ophthalmology and
Visual Sciences, The University of Iowa, Iowa City,
IA
5697 — B0005 Relationship between incidence of post-trabeculectomy posterior capsular cataract and aqueous humor levels of immune mediators.
Katsuhiko Maruyama , Y.
Usui , S.
Ueda ,
T.
Kezuka , H.
Goto . Ophthalmolgy , Tokyo medical university , Tokyo, Japan
5698 — B0006 Investigation of Multiple
Proinflammatory Cytokines in the Aqueous
Humor in Eyes with Neovascular Glaucoma.
Saori Ohira, T.
Inoue, H.
Tanihara . Department of
Ophthalmology, Kumamoto University , Faculty of
Life Sciences , Kumamoto , Japan
5699 — B0007 Multiplex cytokine analysis of aqueous humor in acute primary angle-closure eyes.
Wenbin Huang, S.
Chen , X.
Gao, W. Wang,
M. Zhou, X. Zhang. Zhongshan Ophthalmic Center,
Guangzhou, China
5700 — B0008 Insight into glaucoma damage and resistance pathways through transcript levels of genes that influence mitochondrial function and structure.
Despoina Gkotsi 1, 2 , M.
Shöâeè 3 , G. Lascaratos 1, 2 , D. Chau 3 , A. Schapira 3 ,
D. F. Garway-Heath 1, 2 .
1 Institute of Ophthalmology,
University College London, London, United
Kingdom; 2 NIHR Biomedical Research Centre,
Moorfields Eye Hospital NHS Foundation Trust,
London, United Kingdom; 3 Department of Clinical
Neurosciences, Institute of Neurology, University
College London, London, United Kingdom *CR
5701 — B0009 Altered expression of fibrosis genes in capsules of failed Ahmed glaucoma valve implants.
Al Shahwan
Edward 1, 2 . 1
1
Alka Mahale
, I. Al Jadaan 1
1 , M. W. Othman
, O. A. Owaidhah
Research Department, King Khaled Eye
Specialist Hospital, Riyadh, Saudi Arabia; 2
1
1 , S.
, D.
Wilmer
Eye Institute, Johns Hopkins University School of
Medicine, Baltimore, MD
5702 — B0010 Expression of semaphorin 3F in rat retinal ganglion cells after optic nerve crush.
Ji Ae Ko , C.
Ohki , A.
Minamoto , Y.
Sugimoto , J.
Hirata , Y.
Kiuchi . Department of
Ophthalmology, Hiroshima Univ Grad Sch of
Biomed Sci, Hiroshima, Japan
5703 — B0011 Metabolic profiles associated with primary open-angle glaucoma.
Rachel
M.
Roberson
J. Kuchtey
Brantley 1 .
1
1
1 , K. Uppal 2 , L. Burgess 1
, R. W. Kuchtey 1
2
, V. Tran
, D. P. Jones 2
Department of
Medicine, Emory University, Atlanta, GA
2
Vanderbilt Eye Institute, Vanderbilt
University, Nashville, TN;
,
, M. A.
5704 — B0012 Quantitative Proteomic Analysis of Non-Human Primate (NHP) Peripapillary
(PP) Sclera in Early Experimental Glaucoma
(EEG).
Jack S. Crabb 1, 2 , C. Stowell 3 , G. Jang 1, 2 ,
L. Zhang 1, 2 , B. Willard 2 , C. Burgoyne 3 , J. W.
Crabb 1, 4 .
1 Cole Eye Institute, Cleveland Clinic,
Cleveland, OH; 2 Lerner Research Institute,
Cleveland Clinic, Cleveland, OH; 3 Optic Nerve
Head Research Laboratory, Devers Eye Institute,
Legacy Research Institute, Portland, OR; 4 Depts of
Ophthalmology and Molecular Medicine, Cleveland
Clinic Lerner College of Medicine of Case Western
Reserve University, Cleveland, OH
5705 — B0013 Differential Comparison of
Trabecular Meshwork Ceramides from Control and Glaucomatous Donors.
Ayman Aljohani , Y.
S.
Guerra , S.
K.
Bhattacharya . Bascom Palmer Eye
Inst , Univ of Miami, Miami, FL
5706 — B0014 LOXL1 is involved in the regulation of extracellular matrix-related genes in optic nerve head astrocytes.
Matthias Zenkel,
J. Roth, A. Bergua, F. E. Kruse, U. Schlotzer-
Schrehardt. Department of Ophthalmology,
University Erlangen Nuernberg, Erlangen, Germany
5707 — B0015 Induction of trabecular meshwork cells from human iPSCs by human primary trabecular meshwork cell conditioned media.
Wei Zhu, Q.
Ding , K.
Anfinson , D.
Ahram,
B.
A.
Tucker , M.
H.
Kuehn.
Stephen A.
Wynn
Institute for Vision Research , Department of
Ophthamology , University of Iowa , Iowa City , IA
5708 — B0016 Quantitative protein-antibody array analysis of aqueous humor In glaucoma and cataract.
Darrell WuDunn 1, 3 , S. Ragg 2, 3 , M.
Key 4, 3 , F. Rankin 2, 3 , L. B. Cantor 1 , C. R. Yung 1 ,
Y. Catoira-Boyle 1 , S. Valluri 1 , L. S. Morgan 1 , J. S.
Hoop 1 . 1 Department of Ophthalmology, Indiana
Univ Sch of Medicine, Indianapolis, IN; 2 Pediatrics,
Indiana Univ Sch of Medicine, Indianapolis,
4
IN; 3 Center for Computational Diagnostics,
Indiana Univ Sch of Medicine, Indianapolis, IN;
Mathematical Sciences, Purdue School of Science,
Indianapolis, IN *CR
5709 — B0017 Changed levels of CD4(+)
CD25(+) T cells in glaucoma patients in comparison to healthy controls.
Katharina Bell ,
A.
Holz , N.
Pfeiffer , F.
H.
Grus . Experimental
Ophthalmology, Medical Center Univesity of
Mainz, Mainz, German y
5710 — B0018 Generation of a Novel
Optineurin Knockout Mouse.
Frank S.
Ashburn,
H.
Bomze, C.
McKee, I.
Barak, H.
Tseng.
Ophthalmology, Duke Eye Center , Durham , NC
5711 — B0019 Inflammatory Cytokines in
Aqueous Humor and Plasma are associated with Primary Open angle Glaucoma in a
Brazilian population.
Mariana B.
Oliveira ,
J.
C.
Vasconcellos , V.
P.
Costa, M.
B.
Melo .
Ophthalmology, UNICAMP, Campinas , Brazil
5712 — B0020 The ERK1/2 Kinases May
Be Implicated In Glaucoma.
Wenfeng Hu , X.
Hu , W.
Ji , C.
B.
Toris, Q.
Nguyen , D.
W.
Li .
Ophthalmology & VIsual Sciences , University of
Nebraska Medical Center , Omaha, NE
5713 — B0021 Comparative analysis of
Cholesterol lipids in the trabecular meshwork of
DBA/2J mice.
K. Bhattacharya
Sherif Elsobky
2 .
United Kingdom; 2
1
1, 2 , Y. S. Guerra 2 , S.
Ophthalmology, UCL, London,
Ophthalmology, Bascom Palmer
Hospital, Miami, FL
5714 — B0022 Role of Toll like receptor-4 ligand after neuronal cell degeneration in the mice retina.
Yasunari Munemasa , Y.
Kitaoka, K.
Kojima , A.
Hirano , H.
Takagi . Ophthalmology, St
Marianna University , Kawasaki , Japan
5715 — B0023 Characterization of a
Small, Noncoding RNA in Pseudomonas aeruginosa.
Victoria Addi s
FitzGerald 3 . 1
1 , D. Pastrana 2 , D.
Department of Ophthalmology,
Georgetown University/Washington Hospital
Center, Washington, DC; 2 Laboratory of Cellular
Oncology, National Cancer Institute, Rockville,
MD; 3 Biotherapy Section, National Cancer Insitute,
Rockville, MD
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
376

Thursday – Posters – 5716 – 5733
5716 — B0024 The Role of Hypoxia in
Inducing Aberrant Epigenetic and Fibrotic
States in Glaucoma.
Clark 2 , C. J. O’Brien
Fiona McDonnel
1, 3 , D. M. Wallace
Dublin, Dublin, Ireland; 2 l 1
1, 3
, A. F.
.
1 School of
Medicine and Medical Science, University College
North Texas Eye Research
Institute, University of North Texas Health Science
Center, Ft Worth, TX; 3 Ophthalmology, Mater
Misericordiae University Hospital, Dublin, Ireland
5717 — B0025 Adoptive cell transfer from a glaucoma mouse model induces retinal ganglion cell loss in healthy recipient mice.
Qiong
Ding 1 , O. W. Gramlich 2 , M. G. Anderson 3 , M. H.
Kuehn 1 . 1 Ophthal & Visual Sciences, U of Iowa,
Iowa City, IA; 2 Experimental Ophthalmology,
Department of Ophthalmology, University Medical
Center Mainz, Mainz, Germany; 3 Molecular
Physiology & Biophysics, U of Iowa, Iowa City, IA
5718 — B0026 Expression of primary angle closure glaucoma (PACG) susceptibility gene
PLEKHA7 in cells of the blood aqueous barrier.
Mei Chin Lee
Hilmy 4 , W. Hong
N. Vithana 1, 7 .
1
5, 6
1, 2
, T. Aung
Singapore Eye Research Institute,
Singapore, Singapore; 2
, A. Chan
1, 3
3, 4 , S. Goh
, W. Hunziker
Duke-NUS Graduate
Medical School, Singapore, Singapore; 3
1 , M.
5, 8 , E.
Singapore
National Eye Centre, Singapore,
Singapore; 4 Pathology, Singapore General Hospital,
Singapore, Singapore; 5 Institute of Molecular and
Cell Biology, Singapore, Singapore;
Singapore;
6 Biochemistry,
National University of Singapore, Singapore,
7 Ophthalmology, National University of Singapore, Singapore, Singapore; 8
Singapore
Physiology,
National University of Singapore, Singapore,
5719 — B0027 Direct interaction of cochlin with mechanosensing channel TREK-1.
Teresia
A.
Carreon 1 , M. C. Piqueras 1 , A. Castellanos 2 ,
X. Gasull 2 , S. K. Bhattacharya 1 .
1 Ophthalmology,
University of Miami Bascom Palmer Eye Institute,
Miami, FL; 2 Facultat de Medicina, Universitat de
Barcelona-IDIBAPS, Barcelona, Spain
5720 — B0028 Changes in the levels of selected mechanosensing channels in normotensive versus hypertensive trabecular meshwork.
Phi T. Ho,
G. Edwards, F. Rifai, S. K. Bhattacharya. Bascom
Palmer Eye Institute, University of Miami, Miami,
FL
Exhibit/Poster Hall SA B0029-B0038
Thursday, May 08, 2014 8:30 AM-10:15 AM
Lens
Moderator: Om P. Srivastava
1
5721 — B0029 Biomarkers For Early
Diagnosis Of Diabetic Eye Diseases. Devi
Kalyan Karumanchi 1 , J. Dillon1, E.R. Gaillard 1,2
2
Department of Chemistry and Biochemistry,
Northern Illinois University, Dekalb, IL
Department of Biological Sciences, Northern
Illinois University, Dekalb, IL. Devi Kalyan
Karumanchi , E.
R.
Gaillard , J.
P.
Dillon .
Department of Chemistry and Biochemistry ,
Northern Illinois University , Dekalb , IL
5722 — B0030 AGE-modifications in human lens capsule: Implications for posterior capsule opacification.
Cibin T. Raghavan
Smuda
Nagaraj
2 , M. Glomb
1 .
1
2 , A. Singh 3 , P. Gupta 3
1 , M.
, R. H.
Ophthalmology and Visual Sciences,
Case Western Reserve University, Cleveland,
OH; 2 Institute of Chemistry, Martin-Luther-
University Halle-Wittenberg, Halle/Saale,
Germany; 3 Ophthalmology and Visual Sciences,
University Hospitals of Cleveland, Cleveland, OH
5723 — B0031 Hyperglycemia- and Oxidative
Stress-Induced Hyperoxidation of Prdx 6 during Lens Epithelial Cell Damage and Rat
Lens Opacity in Vitro and in Vivo.
Shinsuke
Shibata 1
Kubo 1 .
1
, D. P. Singh 2 , N. Shibata 1 , H. Sasaki 1 , E.
Department of Ophthalmology, Kanazawa
Medical University, Ishikawa, Japan; 2 Department of Ophthalmology and Visual sciences, University of Nebraska Medical Center, Omaha, NE
5724 — B0032 Lateral Organization of Lipids in Plasma Membranes of Fiber Cells Isolated from Single Donor Human Eye Lenses.
Witold
Subczynski
O’Brien 1 .
1
1 , M. Raguz 1, 2 , L. Mainali 1 , W. J.
Biophysics, Medical College of
Wisconsin, Milwaukee, WI; 2 Medical Physics and
Biophysics, University of Split, Split, Croatia
5725 — B0033 Addition of αA-Crystallin
Sequence 163-173 to αA-Mini-chaperone,
DFVIFLDVKHFSPEDLT Alters The
Conformation But Retains The Chaperone
Activity. Krishna Sharma 1 , R. Murugesan 2 ,
P. Santhoshkumar 2 . 1 Ophthalmology and
Biochemistry, University of Missouri, Columbia,
MO; 2 Ophthalmology, University of Missouri,
Columbia, MO
5726 — B0034 Identification of Crystallin
Cysteine Oxidation Sites in Vitro, in LEGSKO
Mouse and Old Human Lens.
Vincent M.
Monnie r 1, 2 , B. Wang 3 , G. Hom 4 , X. Fan 1 .
1 Pathology,
Case Western Reserve University, Cleveland,
OH; 2 Biochemistry, Case Western Reserve Univ,
Cleveland, OH; 3 Proteomics Center, Case Western
Reserve University, Cleveland, OH; 4 High School,
Fairview Park High School, Fairview Park, OH
5727 — B0035 Determination of Function of
βA3/A1-Crystallin in Lens Development using
βA3/A1-Crystallin Knockout Mice.
Shylaja
Hegde, K.
Srivastava , O.
P.
Srivastava . Vision
Science, University of Alabama Birmingham ,
Birmingham , AL
5728 — B0036 Analysis of βA3-Crystallin
Interaction with αA- and αB-Crystallins.
Ekta
Tiwary , S.
Hegde, O.
P.
Srivastava . vision science, university of Alabama, Birmingham, birmingham,
AL
5729 — B0037 Variant alpha-crystalline expression in age related and congenital cataract.
Jianjun Gu, S. Zhou, J. Yang. Zhongshan
Ophthalmic Center, Guangzhou, China
5730 — B0038 The Relationship Of Cataracts
And Refractive Error In Children With Down
Syndrome.
Frank Weng , O.
Adebona, D.
M.
Ledoux . Boston Children , Boston , MA
Exhibit/Poster Hall SA B0039-B0068
Thursday, May 08, 2014 8:30 AM-10:15 AM
Retinal Cell Biology
5731 — B0039 Visual deficits in mice after mild traumatic brain injury produced by primary overpressure blast are alleviated by the novel CB2 drug SMM189.
Anton Reiner 1, 2 ,
A. Elberger 1 , N. Guley 1 , J. Hines-Beard 4 , J.
Rogers 1 , N. Del Mar 1 , M. Honig 1 , T. S. Rex 4, 2 , C.
Presley 3 , B. M. Moore 3 .
1 Anatomy & Neurobiology,
Univ of Tennessee Health Sci Ctr, Memphis,
TN; 2 Ophthalmology, Univ of Tennessee Health
Sci Ctr, Memphis, TN; 3 Pharmaceutical Sciences,
Univ of Tennessee Health Sci Ctr, Memphis,
TN; 4 Ophthalmology & Visual Sciences, University of Vanderbilt, Nashville, TN
5732 — B0040 Amyloid precursor protein protects against a rodent model of optic neuropathy and is abundant in the human vitreous.
Hayley Waugh, V.
Chrysostomou , J.
G.
Crowston , I.
Trounce.
Centre for Eye Research
Australia, University of Melbourne, Royal Victorian
Eye and Ear Hospital , Melbourne, Australia,
Melbourne, VIC, Australia
5732a — B0040a Methylation sensitive regulation of the EphA5 promoter by KLF16, a zinc finger transcription factor expressed in retinal ganglion cells.
Deborah C.
Otteson, J.
Wang . Optometry, University of Houston, Houston,
TX
5733 — B0041 The scaffold protein mAKAPα regulates retinal ganglion cell survival and axon growth.
J. Hertz 1, 2 , M. D. Kritzer
Goldberg 1, 2 .
1
3
Yan Wang
UC San Diego, La Jolla, CA; 2
1, 2
, M. S. Kapiloff
, J. Li
3
Ophthalmology,
Bascom Palmer Eye Institute, Miami,
FL; 3 Pediatrics and Medicine, Miller School of
Medicine, Miami, FL
3 ,
, J. L.
Ophthalmology, Shiley Eye Center, f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
377

Thursday Posters 8:30 am – 10:15 am
5734 – 5756 – Thursday – Posters
5734 — B0042 Direct and indirect mechanisms of RGC neuroprotection and axon regeneration induced by siRNA-mediated knockdown of the mTOR regulator RTP801 after optic nerve crush.
Peter J. Morgan-Warren 1
ONeill 1
Logan 1
, Z. Ahmed
.
1
1 , M. Berry 1
, J.
, R. Scott 1, 2 , A.
Neurotrauma & Neurodegeneration,
University of Birmingham, Birmingham, United
Kingdom; 2 Royal Centre for Defence Medicine,
Birmingham, United Kingdom *CR
5735 — B0043 Kruppel-like factor 4 (KLF4)
Knockout in Retinal Ganglion Cells Rescues
Optic Neuritis in Experimental Autoimmune
Encephalomyelitis (EAE) Mice.
Venu Talla, T.
Chou , V.
Porciatti, J.
Guy.
Ophthalmology, Bascom
Palmer Eye Institute, Miami, FL
5
5736 — B0044 Minocycline as a neuroprotective agent in a rodent model of NAION.
Simonutti
Bodaghi 1
2
, V. Touitou 1
Audrey Fel
, P. Lehoang 1
.
1 de la Vision, Paris, France;
Baltimore, MD; 4
, S. A. Picaud
Ophthalmology, Pitié Salpétrière
Hospital, Paris, France;
1, 2
2
, N. G. Froger
, S. L. Bernstein 3 , N. Miller 4
2
2 , M.
, B.
, M. Paques
Ophthalmology, Institut
3 Ophthalmology and Visual Sciences, University of Maryland,
2,
Neuro-Ophthalmology, Wilmer
Eye Institute, Johns Hopkins Hospital, Baltimore,
MD; 5 Ophthalmology, DHU View Maintain, CHNO des XV-XX, Paris, France
5737 — B0045 Membrane bound Flt-1 protects against optic nerve degeneration in nerve crush injury in rats.
Zhao Hongwe i 1 , H. Uehara 2 , L.
Luo 1 , C. Nie
Lianna 1
1 , A. Jones 2 , B. Ambati
, Q. Changyu
BeiJing, China; 2
1 . 1
2 , X. Zhang 2 , H.
The 306th hospital of PLA,
Moran Eye Center, Salt Lake, UT
5738 — B0046 Neuroprotective effects of siRNA, targeting Caspase9 on rat retinal damage induced by different time course of transient ischemic injury.
Shinichiro Ishikawa 1
Nakabayashi 2 , R. Iwakiri 1 , S. Okinami
Faculty of Medicine, Saga, Japan;
Hospital, Saga, Japan
1
, A. Hirata
.
1
1 , J.
Saga Univ
2 Saga Memorial
5739 — B0047 Neuroprotective Effects of IGF-
1 on Retinal Ganglion Cell Survival.
Jie Ma , C.
Guo, C.
Guo, T.
Liao , U.
Beattie, G.
Teague , D.
Chen , K.
Lashkari . Schepens Eye Research Inst ,
Boston , MA
5740 — B0048 Efficacy of intravitreal injection of recombinant erythropoietin for protection of retinal ganglion cells in a rat model of retinal ischemia.
Litia Carvalho
Fleming
R. Guimarães 1
Dantas 1
Brazil; 2
Brazil
1 , L. Vitorino
, S. Allodi 1 .
1
1 , M. SantAnna 1
, E. Morizot 2
1 , R.
, M. Fusco 1
, L. Cavalcante 1
,
, A. M.
IBCCF, UFRJ, Rio De Janeiro,
Benjamin Constant Institute, Rio de Janeiro,
5741 — B0049 Eye drops containing pigment epithelium-derived factor promotes retinal ganglion cell neuroprotection and axon regeneration.
Zubair Ahmed, V.
Vigneswara ,
L.
Deer , M.
Esmaeili , M.
Berry, A.
Logan.
Neurotrauma and Neurodegeneration, University of
Birmingham , Birmingham , United Kingdom
5742 — B0050 Identification of p58IPK as a
Novel Protective Factor for Retinal Neuronal
Survival.
Sarah X.
Zhan g 1, 2 , E. Boriushkin 1, 2 ,
G. M. Seigel 2, 3 , J. J. Wang 1, 2 .
1 Departments of Ophthalmology and Biochemistry, SUNY/
University at Buffalo, Buffalo, NY;
Eye Institute, Buffalo, NY; 3
2 SUNY
Department of
Communicative Disorders and Sciences, SUNY/
University at Buffalo, Buffalo, NY
5743 — B0051 In the LPS-induced uveitis model, gp130 activation in retinal neurons and
Müller glia dampens neutrophil infiltration to prevent excessive inflammation.
Marcus J.
Hooper , J.
D.
Ash.
Opthalmology , University of
Florida, Gainesville, FL
5744 — B0052 Amitriptyline induces glialcell line derived neurotrophic factor in retinal cells in vivo and in vitro.
Petr Y. Baranov 1
Sukhanova 1
Morrow 2 , S. Wang 2
J. Young 1 .
1
, O. Yerov 1 , H. Lin
, P. Lei
2 , C. James
2 , J. McNeish 3
2
, T.
, D.
, M.
PA; 3
Schepens Eye Research Institute,
Boston, MA; 2 GlaxoSmithKline, King of Prussia,
GlaxoSmithKline, Boston, MA *CR
5745 — B0053 COMP-Ang1 has retinal neuroprotective properties after hypoxic and vascular insults.
Faisal Ahmed, J.
M.
Cahoon ,
B.
Archer , B.
Ambati . Ophthalmology and Visual
Sciences , John A.
Moran Eye Center , University of
Utah , Salt Lake City , UT
5746 — B0054 Caveolin-1 Modulates
Retinal Neuroprotective And Inflammatory
Cytokine Expression.
Alaina Reagan
D. J. Carr
Elliott 2, 1 .
1
2, 3 , N. A. Mandal 2, 1
1
, J. D. Ash
, X. Gu
4
Oklahoma Center for Neuroscience,
1
, M. H.
,
University of Oklahoma Health Sciences Center,
Oklahoma City, OK; 2 Ophthalmology/Dean
McGee Eye Institute, University of Oklahoma
Health Sciences Center, Oklahoma City,
OK; 3 Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma
City, OK; 4 Department of Ophthalmology Research,
University of Florida, Gainesville, FL
5747 — B0055 Neuroprotective Effects of
Intravitreal Triamcinolone Acetonide and
Dexamethasone Implant in Rabbit Retinas
After Pars Plana Vitrectomy and Silicone Oil
Injection.
Rubens C.
Siqueira 1 , W. F. Santos 1 , I.
U. Scott 3 , A. Messias 1 , M. N. Rosa 1 , G. F. Cunha 2 ,
A. C. Junior 2 , R. Jorge 1 . 1 Ophthalmology, Ribeirão
Preto Medical School, University of São Paulo,
Ribeirao Preto, Brazil; 2 Pharmacology, Minas
Gerais Federal Universityy, Belo Horizonte,
Brazil; 3 Departments of Ophthalmology and Public
Health Sciences, Penn State College of Medicine,
Hershey, PA
5748 — B0056 Human adipose tissue derived mesenchymal stem cells (hAD-MSCs) together with different combinations of factors delay the degeneration of human neuroretina in indirect co-culture system.
Jose-Carlos Pastor, A. K. Singh,
I. Fernandez-Bueno, D. Rodriguez-Crespo, M.
Garcia-Gutierrez, M. Gayoso, G. K. Srivastava.
IOBA-Campus Miguel Delibes, University of
Valladolid, Valladolid, Spain *CR
5749 — B0057 Protective effects of human iPS-derived retinal pigmented epithelial cells in comparison with human mesenchymal stromal cells and human neural stem cells on the degenerating retina in rd1 mice.
Jianan Sun 1
2 , M. Takahashi 1 .
1
, M.
Laboratory Mandai 1 , H. Kamao for Retinal Regeneration, RIKEN Center for
Developmental Biology, Kobe, Japan;
Okayama, Japan
2 Department of Ophthalmology, Kawasaki Medical School,
5750 — B0058 ApoTransferrin preserves photoreceptors from death.
Emilie Picard 1, 2 , M.
Berdugo 1, 2 , M. El Sanharawi
, M. Naud 1, 2
1, 2
, J. Jeanny
, Q. Le Rouzic
1, 2
1, 2 , L.
, Y. G. Courtois 1, 2 , Jonet 1, 2
F. F. Behar-Cohen 1, 3 .
1 Centre de Recherche des
Cordeliers, INSERM, Paris, France; 2
Paris 6 / Paris 5, Paris, France; 3
University
University of
Lausanne, Jules Gonin Hospital, Lausanne,
Switzerland
5751 — B0059 Metformin protects photoreceptors in mice with the PDE6bRd10 mutation and protects RPE in mice treated with sodium iodate.
Lei Xu , H.
Xia, J.
D.
Ash.
Ophthalmology, University of Florida, Gainesville,
FL
5752 — B0060 Leukemia Inhibitory Factor
(LIF) induces survival of Retinal Pigment
Epithelium.
John D.
As h 1 , H. Xia 1 , Y. Huang 1 , L.
Xu 1 , P. Zhu 1 , A. J. Chucair-Elliott 1 Ophthalmology,
FL; 2
2 .
University of Florida, Gainesville, ophthalmology, University of Oklahoma
Health Sciences Center, Oklahoma City, FL
5753 — B0061 Cone Photoreceptors Can
Generate the Potent Neurotrophic and Proangiogenic Fatty Acid Amide Erucamide.
Peter
D. Westenskow
J. Wang 2
Flannery 3
Jolla, CA; 2
1 , T. Kurihara
, L. C. Byrne
, G. Suizdak
3
2
1 , Y. Usui 1
, Y. Wakabayashi 4
, M. Friedlander
Research Institute, La Jolla, CA;
1
, S. Bravo
.
, J. G.
1
1
Cell and
Molecular Biology, Scripps Research Institute, La
Center for Metabolomics, The Scripps
4 Ophthalmology, Tokyo Medical
University Hospital, Tokyo, Japan
3 Helen Wills
Neuroscience, University of California, Berkeley,
Berkeley, CA;
,
5754 — B0062 Retinal neuroprotection using small molecule GDNF mimetics.
H
Uri Saragovi
Jmaeff 1
1 , Y. Sidorova 2 , M. Saarma 2
.
1 Pharmacology, McGill Univ - Jewish
General Hosp, Montreal, QC, Canada; 2
, S.
Medicine,
University of Helsinki, Helsinki, Finland *CR
5755 — B0063 A novel protective role for innate immunity Toll-Like Receptor 3 (TLR3) in retinal degeneration.
Amit K.
Patel, A.
S.
Hackam .
Ophthalmology, University of Miami, Miami, FL
5756 — B0064 Photoreceptor sensitivity to oxidative stress can by regulated by non-redundant roles of PGC-1α and PGC-
1β.
Carolina E. Abrahan, J. D. Ash. Ophthalmology,
University of Florida, Gainesville, FL
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
378

5757 — B0065 Protective effects by inhibition of CNG channels and PKG activity in rd1 mutant photoreceptors.
Evelina Bertolotti
, F. Schwede 2
1 , D.
, V. Marigo Hoffmann 1 , A. Rentsch 2 1 .
1 Life Sciences, University of Modena and Reggio
Emilia, Modena, Italy; 2 BIOLOG Life Science
Institute, Bremen, Germany *CR
2
5758 — B0066 Investigating the Protective
Effects of Dietary Supplementation in Retinal
Degenerations.
Ashley S.
Davi s 1, 2 , A. K. Patel 1, 2 ,
A. S. Hackam 1, 2 . 1 University of Miami, Miami, FL;
Bascom Palmer Eye Institute, Miami, FL
5759 — B0067 Neuroprotective Bioactivity of NPD1 and Dendrimer-NPD1 in the S334ter-5 model of Retinitis Pigmentosa.
Yousef
Cruz Inig
Iezzi 1
MN; 2
. 1 o
C. Gordon 3
1 , M. K. Mishra
, N. Petasis 4
2 , R. Kannan 2
, N. G. Bazan 3
, W.
, R.
Ophthalmology, Mayo Clinic, Rochester,
Wilmer Ophthalmologic Institute, Johns
Hopkins University, Maryland, MD; 3 Neuroscience
Center of Excellence, School of Medicine,
Louisiana State University Health Sciences
Center, New Orleans, LA; 4 University of Southern
California, Los Angeles, CA
5760 — B0068 Different Treatment
Paradigms of 830 nm Photobiomodulation are Retinoprotective in a Rodent Model of
Retinitis Pigmentosa.
Sandeep Gopalakrishnan 1 ,
B. Abroe
Quevedo
2
4
, H. M. Schmitt 3
, P. Summerfelt 5
, A. Gonzalez-
, A. Dubis 6 , J. Carroll 5
J. T. Eells
WI; 2
2 . 1 College of Nursing, University of Wisconsin-Milwaukee, Milwaukee,
,
WI; 4
Biomedical Sciences, University of Wisconsin-
Milwaukee, Milwaukee, WI; 3 Ophthalmology,
University of Wisconsin-Madison, Madison,
Biochemistry, Medical Institute of Havana,
Havana, Cuba; 5 Ophthalmology, Medical College of Wisconsin, Milwaukee, WI; 6
Kingdom *CR
Ophthalmology,
University College London, London, United
Exhibit/Poster Hall SA B0069-B0076
Thursday, May 08, 2014 8:30 AM-10:15 AM
Visual Neuroscience
Moderator: Maureen E. Estevez
5761 — B0069 Effect of age on the electrical response from intrinsically photosensitive retinal ganglion cells.
Matsubara
T. Morita 4
1
.
1
, M. Ayaki 3
Manami Kuze
, K. Tsubota 3
1, 2 , H.
, M. Kondo
Department of Opthalmology, Mie
University School of Medicine, Tsu, Japan;
1 , of Ophthalmology, Mie Central Medical Center,
Tsu, Japan;
Keio University School of Medicine, Tokyo,
Japan; 4
3 Department of Ophthalmology,
Department of Living Enviromental
2 Dept
Science, Fukuoka Women’s University, Fukuoka,
Japan
Thursday – Posters – 5757 – 5778
5762 — B0070 Role for intrinsically photosensitive retinal ganglion cells in modulating dopaminergic amacrine cell development.
Schmidt 1 .
1
Simon Pan 1 , S. Hattar 1, 2 , T. M.
Department of Biology, Johns Hopkins
University, Baltimore, MD;
MD
2 Department of
Neuroscience, Johns Hopkins University, Baltimore,
5763 — B0071 Ocular surface damage and migraine preclinical mouse models of photophobia.
Anna Matynia, S. Parikh, S. Habib,
P. Kim, S. Nusinowitz, M. Gorin. Jules Stein Eye
Institute, UCLA, Los Angeles, CA
5764 — B0072 Influence of Stimulus Size and Luminance on Rod-, Cone-, Melanopsinmediated Pupillary Light Reflexes.
Jason C.
Park ,
J.
McAnany.
Ophthalmology, University of Illinois at Chicago, Chicago, IL
5765 — B0073 Melanopsin-driven responses in the human brain.
Manuel Spitschan 1 , L. Luu 1 , R.
Datta 2 , D. H. Brainard 1 , G. K. Aguirre 2 . 1 Department of Psychology, University of Pennsylvania,
Philadelphia, PA; 2 Department of Neurology,
University of Pennsylvania, Philadelphia, PA *CR
5766 — B0074 Melanopsin-Derived
Signals in the dLGN of the Light-Adapted
Mouse.
Katherine E.
Davis, A.
E.
Allen, R.
J.
Lucas.
Faculty of Life Sciences , The University of
Manchester, Manchester, United Kingdom
5767 — B0075 Influences of melanopsin on cone visual pathways.
Annette E.
Allen, R.
Storchi, T.
Brown, R.
J.
Lucas.
University of
Manchester , Manchester , United Kingdom
5768 — B0076 Human opsin-G-protein fusion proteins as potential light sensitizers.
Doron
Hickey 1 , S. Hughes 1
MacLaren 1
, W. L. Davies 2, 1
, M. Hankins
Ophthalmology, University of Oxford, Oxford,
United Kingdom; 2
1 .
1
, R. E.
Nuffield Lab of
School of Animal Biology and
Oceans Institute, University of Western Australia,
Perth, WA, Australia
Exhibit/Poster Hall SA B0105-B0118
Thursday, May 08, 2014 8:30 AM-10:15 AM
Eye Movements / Strabismus / Amblyopia /
Neuro-Ophthalmology
Moderator: Kenneth S. Shindler
5769 — B0105 Combined inhibition of angiotensin II type 1 receptor and ASK1 significantly attenuates autoimmune optic neuritis.
Xiaoli Guo, K.
Namekata , C.
Harada , T.
Harada . Tokyo Metropolitan Institute of Medical
Science, Tokyo, Japan
5770 — B0106 Dock8 and Dock10 regulate severity of inflammatory demyelination disorders.
Kazuhiko Namekata , X.
Guo, A.
Kimura , C.
Harada , T.
Harada . Visual Research
Project, Tokyo Metropolitan Institute of Medical
Science, Tokyo, Japan
5771 — B0107 HE3286 Reduces Axonal
Loss and Preserves Retinal Ganglion Cell
Function in Experimental Optic Neuritis.
Reas
Sulaimankutty 1 , K. Dine 1 , E. Luna 1 , C. Ahlem 2 ,
2
K. S. Shindler 1 .
1 Ophthalmology, Univ of
Pennsylvania, Scheie Eye Inst, Philadelphia, PA;
Harbor Therapeutics Inc, San Diego, CA *CR
5772 — B0108 Resveratrol and BBI combination therapy in experimental optic neuritis.
Esteban Luna , R.
Sulaimankutty, K.
Dine ,
K.
S.
Shindler . Ophthalmology, University of
Pennsylvania , Philadelphia , PA
5773 — B0109 Distribution of OPA1-
AS1 genetic variants in patients with optic atrophy.
Isao Nakata , E.
D.
Gaier, M.
Janessian,
E.
Delbono, L.
R.
Pasquale , S.
Lessell, D.
M.
Cestari, J.
F.
Rizzo, J.
L.
Wiggs.
Ophthalmology,
Massachusetts Eye & Ear Infirmary, Boston , MA
5774 — B0110 Optical Coherence Tomography in Multiple Sclerosis Patients.
Lucy T.
Xu
2 , A. Nowacki 3 , P. K. Kaiser 4 . 1
1 , R. A.
Bermel Cleveland
Clinic Lerner College of Medicine, Cleveland
3
Clinic, Cleveland, OH; 2 Mellen Center for Multiple
Sclerosis, Cleveland Clinic, Cleveland, OH;
Quantitative Health Sciences, Cleveland Clinic,
Cleveland, OH; 4 Cole Eye Institute, Cleveland
Clinic, Cleveland, OH *CR , f
5775 — B0111 Functional and
Structural Deficits in Patients with
Microcystic Macular Edema.
Mathias
Abegg 1 , F. Borruat 2 .
1 Universitätsklinik für
Augenheilkunde, University of Bern, Bern,
Switzerland; 2 Ophthalmology, University of
Lausanne, Lausanne, Switzerland
5776 — B0112 Different Pattern Of
Ganglion Cell Loss In Eyes Affected By Optic
Neuropathy.
Andrea M.
Coppe, G.
Lapucci, G.
Ripandelli . Ophthalmology, GB Foundation Study
Ophth IRCCS, Rome , Ital y
5777 — B0113 Relation between retinal ganglion cell-inner plexiform layer thickness
(GCIPT) and multifocal visual evoked potentials
(mfVEP) in relapsing-remitting multiple sclerosis
(RRMS) patients.
Divya Narayanan 1 , H. Cheng 1 ,
R. Tang 2 , L. Frishman 1 . 1 College of Optometry,
University of Houston, Houston, TX; 2 MS Eye
CARE clinic, University of Houston, Houston, TX
5778 — B0114 Evaluation of Retinal
Nerve Fiber Layer in patients with idiopathic Optic Perineuritis using Optical
Coherence Tomography.
Jae Ho Jung 1
Lee 1
Choi
, K. Kim 1
2 . 1
, I. Byon 1 , J. Seo 1 , J. E. Lee 2 , H.
Ophthalmology, Pusan Nat,
Busan, Republic of Korea
, J.
Ophthalmology, Pusan Nat, Yangsan,
Republic of Korea; 2 f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
379

Thursday Posters 8:30 am – 10:15 am
5779 – 5796 – Thursday – Posters
5779 — B0115 Measurements by Spectral
Domain OCT in Papilledema are Associated with
Reduced Retinal Nerve Fiber Layer Thickness after Resolution of Optic Disc Swelling.
Berthold
Pemp, A. Reitner, K. Kircher, U. Schmidt-Erfurth.
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
5780 — B0116 Retinal Ganglion Cell Layer
Thinning and Vision Outcome in NAION and Optic Neuritis over Six Months.
Jui-Kai
Wang 1 , M. J. Kupersmith 2 , M. K. Garvin 3, 1 , R. H.
Kardon 3, 4 .
1 Department of Electrical and Computer
Engineering, The University of Iowa, Iowa
City, IA; 2 Department of Neuro-Ophthalmology,
Roosevelt Hospital and NYEE, New York, NY; 3 VA
Center for the Prevention and Treatment of Visual
Loss, Iowa City VA Health Care System, Iowa City,
IA; 4 Department of Ophthalmology and Visual
Sciences, The University of Iowa, Iowa City,
IA *CR
5781 — B0117
Acid, Bilirubin and Albumin in Patients with
Optic Neuritis.
Antioxidant Status of Uric
Juan deng. Ophthalmology, The
Third Affiliated Hospital of Sun Yat-sen University,
GuangZhou, China
5782 — B0118 Visual function and retinal nerve fiber layer thickness in Neuromyelitis optica: a longitudinal and comparative study.
Rabih
HAGE 1, 2 , P. Cabre 1 , H. Merle 1 .
1 Ophthalmology,
Fort-de-France University Hospital, Fort-de-France,
Martinique; 2 NeuroOphthalmology, EMORY
University, Atlanta, GA
Exhibit/Poster Hall SA B0208-B0217
Thursday, May 08, 2014 8:30 AM-10:15 AM
Physiology/Pharmacology
Moderator: Marina Roizenblatt
5783 — B0208 Innovative Aqueous
Azithromycin Ophthalmic Formulation.
Maria G.
Saita, D.
Aleo , S.
Mangiafico , B.
Melilli, M.
G.
Cro,
S.
Mangiafico . R&D, Medivis, Catania, Italy *CR
5784 — B0209 Correlation of
Phenotypic Expression of Methicillin
Resistance with Genotype and In Vitro
Susceptibility for mecA+ Staphylococcus epidermidisEndophthalmitis Isolates.
Laura C.
Huan g
Miller 2
1 , J. Stringham 2 , J. Wong 1
, H. W. Flynn 2 . 1
Eye Institute, Miami, FL
, J. Maestre
School of Medicine, Miami, FL; 2
2 , D.
University of Miami Miller
Bascom Palmer
5785 — B0210 Bactericidal Activity of
Levofloxacin against Staphylococcus aureus and Staphylococcus epidermidis in an In
Vitro Pharmacokinetic Model Simulating
Concentration in the Bulbar Conjunctiva after
Eye Drop.
Takashi Suzuki , T.
Yamamoto , Y.
Ohashi . Ophthalmology, Ehime University School of Medicine , Toon , Japan *CR
5786 — B0211 Cytotoxicity of Ophthalmic
Antimicrobial Solutions on SV40-immortalized
Human Corneal Epithelial Cells.
Jae Lim
Chung 1 , Y. Kwon 1 , S. Song 1
K. Seo 2 , C. Ta 3 .
1
, B. Kim 1 , J. H. Lee 1 ,
Ophthalmology, Myung-Gok Eye
Research Institute, Kim’s Eye Hospital, Konyang
University College of Medicine, Seoul, Republic of Korea; 2 Ophthalmology, Institute of Vision
Research, Yonsei University College of Medicine,
Seoul, Republic of Korea;
Medicine, Palo Alto, CA
3 Ophthalmology, Byers
Eye Institute, Stanford University School of
5787 — B0212 5% Betadine solution in not effective in inhibiting the growth of different Gram Negative and Gram Positive
Pathogens in vitro.
Eric Huynh 1 , P. Tran 1, 2 ,
P. Pham 1 , A. Hamood 2 , K. Mitchell 1 , T. W.
Reid 1, 2 .
1 Ophthalmology and Visual Sciences,
Texas Tech Univ Health Sciences Ctr, Lubbock,
TX; 2 Immunology and Molecular Microbiology,
Texas Tech University Health Sciences Ctr,
Lubbock, TX
5788 — B0213 Effect of biguanide on excystment, proliferation and death of Acanthamoeba strains.
Marina Roizenblatt, L.
C.
Carrijo-Carvalho , A.
S.
Foronda, F.
R.
Carvalho ,
D.
Freitas.
Department of Ophthalmology and
Visual Sciences , Paulista School of Medicine , São
Paulo Hospital , Federal University of São Paulo,
São Paulo, Brazil
5789 — B0214 Corneal Pharmacokinetics of Meropenem.
Henri Sueke 1, 2 , T. Neal 1 ,
S. J. Tuft 3 , M. Wilkinson 2 , Y. Zheng 2 , C.
Winstanley 2 , S. Kaye 1, 2 .
1 Ophthalmology, Royal
Liverpool University Hospital, Liverpool,
United Kingdom; 2 Eye and Vision Science,
University of Liverpool, Liverpool, United
Kingdom; 3 Ophthalmology, Moorfields Hospital,
London, United Kingdom
5790 — B0215 Besifloxacin Ophthalmic
Suspension, 0.6% Compared with Gatifloxacin
Ophthalmic Solution, 0.3% for the Treatment of Bacterial Conjunctivitis in Neonatal
Patients.
Tuyen On g
B. Sforzolini 1
1 , C. Allaire 3 , T. W. Morris 2 ,
Clinical Development, Bausch & . 1
Lomb Incorporated, Madison, NJ; and Sterilization Sciences, Bausch & Lomb
Incorporated, Rochester, NY; 3
2 Microbiology
European
Pharmaceutical Clinical Science, Bausch & Lomb
Incorporated, Evry Cedex, France *CR , f
5791 — B0216 Optimizing fluence settings and riboflavin composition for collagen cross-linking (CXL) in the antimicrobial efficiency against Pseudomonas aeruginosa and Staphylococcus aureus.
Olivier Richoz 1 ,
F. Hoogewoud 1 , D. Tabibian 1 , A. Hammer 1 , F.
Hafezi 1, 2 .
1 Ophthalmology, Geneva University
Hospital, Geneva, Switzerland; 2 Ophthalmology,
Southern California, Doheny Eye Institute, Keck
School of Medicine, Los Angeles, CA *CR
5792 — B0217 Comparative Anti-Fungal
Susceptibility Analysis of Candida Albicans versus Non-Albicans Candida Corneal
Isolates.
Oriel Spierer, J.
R.
Dugar, D.
Miller , T.
P.
O’Brien.
Ophthalmology, Bascom Palmer Eye
Institute, Palm Beach Gardens, FL
Exhibit/Poster Hall SA B0218-B0239
Thursday, May 08, 2014 8:30 AM-10:15 AM
Immunology/Microbiology
Moderator: Joyce H. Yamamoto
5793 — B0218 The value of rescreening in primary retinal vasculitis.
Mirjam E.
Van
Velthoven 1 , S. Baarsma 1
A. van Laar 2
, P. M. Van Hagen
, T. Missotten 1
2
Rotterdam Eye Hospital, Rotterdam,
Netherlands; 2
. 1
, J.
Ophthalmology,
Department of Clinical Immunology,
Erasmus Medical Center, Rotterdam, Netherlands
5794 — B0219 Use of Perfluoron in Obtaining
Large-Volume Undiluted Vitreous Specimens for Diagnostic Vitreous Biopsy.
Joseph Merck 1 ,
P. Merrill 1, 2 , R. Duval
Center, Chicago, IL; 2
3, 4 .
1 Rush University Medical
Illinois Retina Associates,
Chicago, IL;
QC, Canada;
3
4
University of Montreal, Montreal,
Maisonneuve-Rosemont Hospital,
Montreal, QC, Canada
5795 — B0220 Retinal biopsy in patients with ocular sarcoidosis and patients with rhegmatogenous retinal detachment.
Kenji
Nagata , K.
Yoneda , H.
Hatanaka , S.
Kinoshita.
Department of Ophthalmology, Kyoto Prefectural
University of Medicine , Kyoto, Japan
5796 — B0221 Incremental Cost-Effectiveness of Fluocinolone Acetonide Implant vs Systemic
Therapy for Non-infectious Intermediate,
Posterior, and Pan-Uveitis.
Elizabeth A.
Suga r 1, 2 ,
J. T. Holbrook 2
L. T. Drye 2
Jabs 6, 7
, J. H. Kempen 4, 5 , A. E. Burke 2 ,
, J. E. Thorne
, M. M. Altaweel 8
3 , T. A. Louis
, K. Frick 9 . 1
1 , D. A.
Biostatistics,
Bloomberg Sch Public Hlth-JHU, Baltimore,
MD; 2 Center for Clinical Trials, The Johns
Hopkins Bloomberg School of Public Health,
Baltimore, MD;
MD; 4
3 Ophthalmology, The Johns
Hopkins University School of Medicine, Baltimore,
Ocular Inflammation Service, The University of Pennsylvania, Philadelphia, PA; 5 Center for Clinical Epidemiology and Biostatistics,
Department of Biostatistics and Epidemiology,
The University of Pennsylvania, Philadelphia,
PA; 6 Ophthalmology, The Icahn School of Medicine at Mount Sinai, New York, NY; 7 Medicine, The
Icahn School of Medicine at Mount Sinai, New
York, NY; 8 Opthalmology and Visual Sciences,
University of Wisconsin, Madison, WI; 9 Carey
Business School, The Johns Hopkins University,
Baltimore, MD *CR , f
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
380

5797 — B0222 A new and standardized method to sample and analyse vitreous biopsies in unsolved uveitis by the Cellient ® automated cell block system.
Joachim van Calster, R.
Van
Ginderdeuren . Ophthalmology, University Hospitals
Leuven , Leuven , Belgium *CR
5798 — B0223 Adalimumab treatment in patients with Vogt-Koyanagi-Harada
Syndrome.
Cristobal A.
Couto, M.
Frick, E.
M.
Hurtado Jallaza, M.
Lopez, B.
A.
Schlaen.
Ophthalmology, University of Buenos Aires,
Buenos Aires, Argentina
5799 — B0224 Clinical course of Vogt-
Koyanagi-Harada disease in Brazilian patients.
Joyce H.
C. E. Hirata
Y. Takahashi
1
1
Yamamoto
, M. C. Marin 4
1 , V. M. Sakata 1
, H. Rodrigues 4
, R. A. Costa 2, 3 . 1
,
, W.
Ophthalmology,
University of Sao Paulo, Sao Paulo, Brazil;
2 DIvision of Macular, Centro Brasileiro de Ciências
Visuais, Belo Horizonte, Brazil;
Universidade de São Paulo Faculdade de Medicina,
Ribeirão Preto, Brazil; 4
3 Ophthalmology,
Laboratory of Immunology,
Heart Institute, Universidade de Sao Paulo,
Faculdade de Medicina, Sao Paulo, Brazil
5800 — B0225 Vogt Koyanagi Harada disease in pediatric patients.
vanessa valderrama, M.
Pedroza-Seres. Uvea, instituto de oftalmologia conde de valenciana, mexico, Mexico
5801 — B0226 Diagnostic and prognostic value of cerebrospinal fluid analysis in Vogt-
Koyanagi-Harada syndrome.
Alexandra
Mouallem 1
Champion 1
Cassoux 2
, V. Touitou
, A. Darugar
, P. Lehoang 1 .
1
1
, B. Bodaghi
1 , C. Fardeau
1
1
, E.
, N.
Ophthalmology, DHU
View Maintain, Pitié Salpétrière Hospital, Paris,
France;
France
2 Ophthalmology, Institut Curie, Paris,
5802 — B0227 Retinal pigment epithelium striations in Vogt-Koyanagi-Harada disease: A new biomarker for visual prognosis.
Kouhei Hashizume 1 , Y. Imamura 2 ,
T. Fujiwara 1 , S. Machida 1 , M. Ishida 2 , D.
Kurosaka 1 .
1 Ophthalmology, Iwate Medical
University, Morioka, Japan; 2 Ophthalmology,
Teikyo University School of Medicine,
Mizonokuchi Hospital, Kawasaki, Japan
5803 — B0228 Corneal specular microscopy findings in Behcet’s disease.
Banu Turgut Ozturk ,
B.
Bozkurt, A.
Beyoglu, S.
Gonul, S.
Okudan .
Ophthalmology, Selcuk University , Konya,
Turkey *CR
5804 — B0229 Changes in Ocular
Manifestations of Behçet’s Disease in Korean
Patients over Time: A Single Center Experience in the 1990s and 2000s.
Ji Hun Song 1
Chung 3 , E. Lee 2 , M. Kim 1 , H. Lew 1 .
1
, Y.
Department of Ophthalmology, Ajou University School of
Medicine, Suwon, Republic of Korea;
Medicine, Suwon, Republic of Korea;
2 Department of Dermatology, Ajou University School of of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of
Korea
3 Department
5805 — B0230 Increased Serum Interleukin-23
Levels In Patients With Behçet Disease-
Associated Uveitis.
Ozlem Gurses 1, 2 , E. Kartal
Koç 1, 3 .
1 Ophthalmology, Middle East Technical
University, Oran ankara, Turkey; 2 uveitis, The
World Eye Hospital, Ankara, Turkey; 3 statistics,
University of Tennessee, Knoxville, TN
5806 — B0231 Real-world observational multicenter study of intravitreal dexamethasone implant (Ozurdex characteristics, clinical outcomes and reinjection frequency.
E. Carreno 2
Robert
A. Adan Civera 4
1
® ) in Uveitis: Baseline
Johnston
, A. Ross 2
1
, A. Fonollosa
, R. W. Lee 2
, J. Zarranz-Ventura 2, 1
3 , L. Pelegrin 4
, A. D. Dick 2
Retinal Service, Cheltenham General
2
, A. A.
,
,
Sallam 1 .
Hospital, Cheltenham, United Kingdom; service, Bristol Eye Hospital, Bristol, United
Kingdom; 3 Uveitis service, Hospital de Cruces,
Bilbao, Spain; 4
Uveitis
Uveitis service, Hospital Clinic,
Barcelona, Spain *CR
5807 — B0232 Efficacy of the dexamethasone implant Ozurdex ® for the re-treatment of refractive cystoid macular edema in noninfectious uveitis.
Arnd Heiligenhaus , M.
Breitbach, D.
Rack , M.
Dietzel, C.
Heinz.
Ophthalmology, St Franziskus Hospital , Muenster ,
German y
5808 — B0233 The use of Ozurdex in patients with chronic, recurrent uveitis undergoing anterior segment surgery.
Ashwinee Ragam
.
1
1 , A.
The M. Kolomeyer 1 , N. V. Nayak 1 , D. S. Chu 1, 2
Institute of Ophthalmology and Visual Science,
Rutgers New Jersey Medical School, Newark,
NJ; 2 Metropolitan Eye Research and Surgery
Institute, Palisades Park, NJ *CR
5809 — B0234 Reactive and infiltrative papillitis in uveitis: response to treatment and use of optic nerve optical coherence tomography for monitoring.
Lucia Sobrin 1 , L.
Nicholson 1 , P. Pillai 1 , H. Cho 1, 2 . 1 Retina/Uveitis,
Harvard Med Mass Eye & Ear Infirmary, Boston,
MA; 2 Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of Korea
5810 — B0235 Anterior-Segment Optical
Coherence Tomography Findings In Eyes With
Scleritis.
Noriyasu Hashida, K.
Nishida.
Dept of
Ophthalmology, Osaka University Graduate School of Medicine , Suita, Japan f
5811 — B0236 Analysis of Foveal Variability with Optical Coherence Tomography in Multiple
Evanescent White Dot Syndrome.
Marcela
Marsiglia 1, 2 , E. Cunha Souza 8 , S. Mrejen 2 , T. A.
Albini 4 , R. Gallego-Pinazo 5, 2 , S. Yu 6, 2 , A. Gaudric 7 ,
K. Freund 2, 3 , L. A. Yannuzzi 2, 3 . 1 Columbia
University, New Yok, NY; 2 VRMNY, Nw York,
NY; 3 NYU, New York, NY; 4 Bascom Palmer,
Miami, FL; 5 Unit of Macula. Department of
Ophthalmology., University and Polytechcnic
Hospital La Fe., Valencia, Spain; 6 Dept. of
Ophthalmology, Shanghai Jiaotong University affiliated Shanghai First People’s Hospital,
Shanghai, China; 7 Hospitale Lariboisiere, Paris,
France; 8 UNIFESP, Sao Paulo, Brazil *CR
Thursday – Posters – 5797 – 5817
5812 — B0237 Spectral-domain optical coherence tomography imaging in patients with uveitis: Assesment of the integrity of the IS/OS line.
Maria de las Mercedes Frick
C. Ampuero
Lopez 1
A. Couto 1 .
1
1 , F. Pascuet 2 , B. A. Schlaen
2
Exhibit/Poster Hall SA C0001-C0027
Thursday, May 08, 2014 8:30 AM-10:15 AM
Retinal Cell Biology
1 , M.
, A. Delbene
1 ,
First Private Eyes
Hospital, Buenos Aires, Argentina
2 , C.
Ophthalmology, University of Buenos
Aires, Buenos Aires, Argentina;
5813 — B0238 Topographic Choroidal
Thickness Analysis of the Macula by Swept
Source Optical Coherence Tomography in
Unilateral Multifocal Choroiditis.
Brendan
Butler 2, 3 , P. Hernandez-Martinez 1 , I. Pascual-
Camps 1 , A. de Freytas 1 , M. Andreu-Fenoll 1 , R.
Dolz-Marco 1 , J. J. Jung 5, 4 , M. Marsiglia 5, 3 , S.
Mrejen 4, 3 , R. Gallego-Pinazo 1 .
1 Unit of Macula.
Department of Ophthalmology, University and Polytechnic Hospital La Fe, Valencia,
Spain; 2 Ophthalmology, New York University, New
York, NY; 3 LuEsther T. Mertz Retinal Research
Center, Manhattan Eye, Ear and Throat Hospital,
New York, NY; 4 Vitreous - Retina - Macula
Consultants of New York, New York, NY; 5 Edward
S. Harkness Eye Institute, Columbia University
College of Physicians and Surgeons, New York,
NY *CR
5814 — B0239 SS- OCT analysis of choroidal involvement in patients with uveitis.
Eleonore
DIWO , A.
Darugar, N.
Massamba , P.
Lehoang,
S.
Razavi , B.
Bodaghi.
Ophthalmology, DHU
ViewMaintain , Pitie Salpetriere Hospital , PARIS,
France
, E. M. Hurtado Jallaza 1
Moderator: Sarah X. Zhang
5815 — C0001 Regulation of Crystallins in Primates and Humans during Diabetic
Retinopathy.
Patrice E.
Fort , W.
Zhang, N.
Chandrasekar , K.
Green.
Ophthalmology and Visual
Sciences , University of Michigan , Ann Arbor, MI
5816 — C0002 Aerobic Exercise Sustains
Retinal Function and Retinal Dopamine
Metabolism in Diabetic Rats.
Brian C. Prall 1 ,
M. H. Aung 1 , M. Gogniat
, J. H. Boatright 2
1 , R. S. Allen
, P. M. Iuvone
1
2, 3
, C. S.
Sidhu 2
Pardue 2, 4 .
1
, M. T.
Neuroscience, Emory University,
Atlanta, GA;
Atlanta, GA;
2
3
Ophthalmology, Emory University,
Atlanta, GA; 4
Pharmacology, Emory University,
Rehab Center of Excellence, Atlanta
VA Medical Center, Decatur, GA
5817 — C0003 Exogenous αB-crystallin promotes tubulogenesis in human retinal endothelial cells.
Ram H.
Nagaraj, S.
Howell , R.
B.
Nahomi . Ophthalmology and Visual Sciences , Case
Western Reserve University , Cleveland, OH f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
381

Thursday Posters 8:30 am – 10:15 am
5818 – 5840 – Thursday – Posters
2
5818 — C0004 Diabetic retinopathy in transgenic pigs with induced diabetes mellitus.
Masami Nakajima 1
Umeyama 2 , H. Nagashima 2 . 1
, A. Ishimori 1
Univ School of Medicine, Itabashi-Ku, Japan;
Meiji University International Institute for Bio-
Resource Research, Kawasaki, Japan
, K.
Ophthalmology, Nihon
5819 — C0005 Dystrophin-Dp71-null mouse presents retinal vascular inflammation.
Brahim
El Mathari 1, 2
M. J. Roux 5
Rendon 1 .
1
, H. Charles-Messance
, J. A. Sahel
1 , C. Grepin
1, 3 , R. Tadayoni 1, 4 , A.
Therapeutic, Institut de la Vision/
2 ,
INSERM/UPMC Univ Paris 06/CNRS/CHNO des Quinze-Vingts, Paris, France;
Institut de la vision, Paris, France;
2
3
Sanofi-Fovea,
Fondation
Ophtalmologique Adolphe de Rothschild, Paris,
France; 4 Ophthalmology Dept, Hôpital Lariboisière,
AP-HP, Univ Paris Diderot, Paris, France; 5 de Génétique et de Biologie Moléculaire et
Institut
Cellulaire, CNRS UMR_7104, Inserm U 964,
Université de Strasbourg, Strasbourg, France *CR
5820 — C0006 Angiopoietin-like 4 is a Potent
Angiogenic Factor in Patients with Proliferative
Diabetic Retinopathy.
Kathleen J. Jee 1
Babapoor 1 , J. Hassan
G. L. Semenza 2
1 , Y. Daoud
, S. Montaner 3
1
, A. Sodhi 1
, S.
, S. D. Solomon
.
1
Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD; 2 Departments of
Pediatrics, Medicine, Oncology, and Radiation
Oncology, Johns Hopkins University School of Medicine, Baltimore, MD; 3
1
Wilmer
Department of
Oncology and Diagnostic Sciences, University of
Maryland Greenebaum Cancer Center, Baltimore,
MD
,
5821 — C0007 Angiofibrotic Response to
Bevacizumab on Fibrovascular Membranes in
Proliferative Diabetic Retinopathy.
Chunhua
Jiao 3 , 1 , C. Spee
D. R. Hinton 2
2 , S. He 2 , R. Mullins
, E. H. Sohn 1 .
1
1 , D. Eliott
Department of
Ophthalmology & Wynn Institute for Vision
2
Research, University of Iowa, Iowa City, IA;
Doheny Eye Institute, University of Southern
California Keck School of medicine, Los Angeles,
CA; 3 Massachusetts Eye and Ear Infirmary, Harvard
Medical School, Boston, MA *CR , f
5822 — C0008 Downregulation of Connexin
43 Expression and Gap Junction Intercellular
Communication Promotes Apoptosis in Retinal
Müller Cells.
Sayon Roy 1 , T. Tien 1 ,
V. P. Sarthy 2 .
1
1 , T. Muto
Medicine & Ophthalmology,
Boston University Sch of Med, Boston, MA;
2 Ophthalmology, Northwestern University Feinberg
School of Medicine, Chicago, IL
5823 — C0009 Expression of Water/ion
Channels and Inflammatory Markers in the
Retina of Goto-Kakizaki Type 2 Diabetic Rat:
Contribution of Mineralocorticoid Receptor
Pathway.
Min Zhao
P. Lassiaz 1
1 , E. Bousquet
, F. F. Behar-Cohen 1, 3
U872, Team 17, Paris, France; 2
.
1
1, 2 , J. Jeanny
CRC, Inserm department of Ophthalmology, AP-HP, Hôtel-Dieu, Paris,
France; 3 Hôpital Ophtalmique Jules-Gonin,
Lausanne, Switzerland
1 ,
5824 — C0010 Sphingosine-1-Phosphate
Pathway: Role in Pericyte-Endothelial
Interactions in Diabetic Retinopathy.
Carolina
Franco Nitta
McGuire 3, 1
1, 2 , F. Monickaraj
, A. Das 1, 2
Mexico, Albuquerque, NM; 2
1 , A. Lucero 3, 2 , P.
.
1 Surgery, University of New
Surgery, NMVA Health
Care System, Albuquerque, NM; 3 Cell Biology and Physiology, University of New Mexico,
Albuquerque, NM *CR
5825 — C0011 Monocytes/macrophages alter the blood-retinal barrier by secretion of cytokines and growth factors in diabetic retinopathy.
Finny Monickaraj
A. Lucero 3 , P. McGuire 3, 1
1 , C. Franco Nitta 1, 2
, A. Das 1, 2 .
1 Surgery/
Opthalmology, University of New Mexico,
Albuquerque, NM; 2 Surgery, NMVA Health
Care System, Albuquerque, NM; 3 Cell Biology and Physiology, University of New Mexico,
Albuquerque, NM *CR
,
5826 — C0012 Intravitreal injection of
IGFBP-3 restores normal insulin signaling in diabetic rat retina.
Qiuhua Zhan g 1 , Y. Jiang 1 , J.
J. Steinle 1 1, 2 . Ophthalmology, Univ of Tennessee
Hlth Sci Ctr, Memphis, TN; 2 Anatomy and
Neurobiology, University of Tennessee Health
Science Center, Memphis, TN
5827 — C0013 ProNGF causes retinal endothelial cell permeability via activation of p75NTR/RhoA pathway.
Rodenbeck 1, 2
B. El-Remessy 1, 2 .
1
, A. Y. Shanab
Barbara A. Mysona
1, 2 , S. Matragoon 1, 2
1, 2
GA; 2 Culver Vision Discovery Institute, Georgia
Regents University, Augusta, GA
, D.
, A.
UGA Clinical and Experimental
Therapeutics, University of Georgia, Augusta,
5828 — C0014 Serine 307 on Insulin Receptor
Substrate 1 is Key to Tumor Necrosis Factor alpha and Suppressor of Cytokine Signaling 3
Action in Müller cells.
Youde Jian g 1 , Q. Zhang 1 ,
J. J. Steinle 1, 2 . 1 Ophthalmology, UT Health Science
Center, Memphis, TN; 2 Anatomy and Neurobiology,
University of Tennessee Health Science Center,
Memphis, TN
5829 — C0015 The Role of GAPDH/Siah1
In Human Retinal Pericyte Apoptosis.
Sandra
Suarez 1 , J. S. Penn 1, 2 . 1 Cell and Developmental
Biology, Vanderbilt University School of Medicine,
Nashville, TN;
Nashville, TN
2 Ophthalmology and Visual
Sciences, Vanderbilt University School of Medicine,
5830 — C0016 Deletion of IDO prevents diabetes-induced retinal capillary degeneration in mice.
Rooban B. Nahomi 1 , M. Mailankot 1 , T.
Kern 2 , J. Tang
Nagaraj 1
2 , A. Lee 2 , S. Sampathkumar 1 , R. H.
.
1 Ophthalmology and Visual Sciences,
Case Western Reserve University, Cleveland,
OH; 2 Medicine, Case Western Reserve University,
Cleveland, OH
5831 — C0017 Direct downregulation of
Connexin 43 expression promotes retinal vascular cell loss characteristic of diabetic retinopathy.
Tetsuya Muto, S. Roy. Medicine and
Ophthalmology, Boston University, Boston, MA
5832 — C0018 Mismatch Mitochondrial DNA
Sequence in Diabetic Retinopathy.
Manish
Mishra , R.
Kowluru.
Kresge Eye Institute, Detroit,
MI
5833 — C0019 Neuroprotective and regenerative effect of taurine-conjugated urosodeoxycholic acid in rat retinas exposed to high glucose.
Toshiyuki Oshitari , G.
Bikbova, S.
Yamamoto . Ophthalmology, Chiba Univ Grad Sch of Med, Chiba, Japan
5834 — C0020 Protein Deacetylases
Sirt1 and Epigenetic Modification of
Matrix Metalloproteinase-9 in Diabetic
Retinopathy.
Renu Kowluru, J.
M.
Santos .
Ophthalmology, Kresge Eye Institute, Detroit, MI
5835 — C0021 Insulin-induced nitric oxide production under high glucose condition in microvessels of rat retina.
Teruyo Kida , H.
Oku,
T.
Horie, T.
Ikeda.
Ophthalmology, Osaka Medical
College, Takatsuki, Japan
5836 — C0022 Regenerative effects of different neurotrophic factors on isolated rat retinas exposed to high dose AGEs.
Guzel Bikbova, T.
Oshitari , S.
Yamamoto . Ophthalmology & Visual
Science, Chiba Univ Grad School of Medicine ,
Chuo ku , Japan
5837 — C0023 Aflibercept’s potency to block or revert VEGF-stimulated behavior of retinal endothelial cells.
Heidrun L.
Deissler , G.
K.
Lang , G.
E.
Lang . Department of Ophthalmology,
University of Ulm, Ulm, Germany *CR
5838 — C0024 The Role of Cytochrome P450
Epoxygenases and Their Epoxyeicosatrienoic
Acid Products in Diabetes-induced Retinal
Inflammation.
Megan E.
Capozzi, S.
Suarez , J.
S.
Penn . Molecular Physiology and Biophysics ,
Vanderbilt University School of Medicine ,
Nashville, TN
5839 — C0025 Endoplasmic reticulum stress is associated with pericyte loss at early retinopathy of streptozotocin-induced diabetic mice.
Yoo-Ri Chung 1 , J. Choi 3 , M. Kang 4 , J. Koh
Ophthalmology, Asan Medical Center,
2, 3 ,
Y. Yoon 1 .
1
Seoul, Republic of Korea; 2 Neurology, Asan
Medical Center, Seoul, Republic of Korea; 3 Neural
Injury Research Center, Asan Medical Center,
Seoul, Republic of Korea;
Republic of Korea *CR
4 Biomedical Science,
University of Ulsan College of Medicine, Seoul,
5840 — C0026 M1 and M2 Macrophage in
Proliferative Diabetic Retinopathy: Altered
Macrophage Polarization by Bevacizumab in Diabetic Fibrovascular Membranes.
Yedi
Zhou 1 , S. Nakao
Y. Sassa 1
Ishibashi 1
1 , S. Yoshida 1 , K. Ishikawa 1
, Y. Oshima 1 , H. Enaida 1 , T. Kono 2
,
, T.
.
1 Department of Ophthalmology, Kyushu
University Graduate School of Medical Sciences,
Fukuoka, Japan;
Japan
2 Department of Ophthalmology,
Fukuoka University Chikushi Hospital, Fukuoka,
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
382

Thursday – Posters – 5841 – 5855
5841
Microvascular Glycocalyx in the Diabetic Rat
Retina Occurs with an Increase in Circulating
Levels of Matrix Metalloproteinases.
R.
—
Harris
C0027
,
Physiology
Shreveport
R.
,
,
S.
Loss of the Retinal
Eshaq.
Molecular
LSU Health
LA
Sciences
&
Norman
Cellular
Center ,
Exhibit/Poster Hall SA C0028-C0070
Thursday, May 08, 2014 8:30 AM-10:15 AM
Multidisciplinary Ophthalmic Imaging / Retinal
Cell Biology / Retina
Moderators: Kevin C. Chan and
Dirk-Uwe G. Bartsch
5842 — C0028 Magnetic Resonance Imaging and Computerized Tomography for the
Detection and Characterization of Non-metallic
Intraocular Foreign Bodies.
Elad Moisseiev 1, 2 ,
2
D. Last 3
.
1
, D. Goez 3 , A. Barak
University, Tel Aviv, Israel; 3
1, 2 , Y. Mardor 3,
Ophthalmology, Tel Aviv Medical Center, Tel
Aviv, Israel; 2 Sackler School of Medicine, Tel Aviv
Advanced Technology
Center, Sheba Medical Center, Tel Hashomer, Israel
5843 — C0029 MRI Detection of Retinal
Hemorrhages: Correlation with Graded
Ophthalmologic Exam.
Anna Stagner 1 , A.
Beavers 2 , S. Allbery 3 , E. Lyden
Hejkal 1 .
1
Center, Omaha, NE; 2
4 , S. Haney 5 , T.
Truhlsen Eye Institute, Department of
Ophthalmology, University of Nebraska Medical
Department of Radiology,
University of Nebraska Medical Center, Omaha,
NE; 3 Department of Radiology, Children’s Hospital and Medical Center, Omaha, NE; 4 College of Public
Health, University of Nebraska Medical Center,
Omaha, NE; 5 Department of Pediatrics, Children’s
Hospital and Medical Center, Omaha, NE
5844 — C0030 Disease in the photoreceptors
(JMD) or retinal ganglion cells (LHON) affects optic tract and radiation tissue properties.
Y. Masuda 3, 2
Shumpei Ogawa
H. Horiguchi
J. D. Yeatman
2
.
1
1
, M. Terao 5, 4
Stanford, CA; 2
, H. Tsuneoka 2
1, 2 , H. Takemura 1, 4
, T. Haji 6 , F. Pestilli 1
, B. A. Wandell 1 ,
,
,
Psychology, Stanford University,
Ophthalmology, The Jikei University
School of Medicine, Tokyo, Japan; 3 Ophthalmology,
Atsugi City Hospital, Kanagawa, Japan; 4 The
Japan Society for the Promotion of Science, Tokyo,
Japan; 5 Psychology, The University of Tokyo,
Tokyo, Japan; 6 Tamagawa University Brain Science
Institute, Tokyo, Japan
5845 — C0031 High resolution MR imaging of the human eye and orbit at 7T using a dedicated
6-channel eye coil - impact of an optoacoustic triggered MR protocol on imaging quality.
Oliver
Stachs
Hosten
1
4
, T. Lindner 2 , J. Rieger 3 , R. Guthoff
, S. Hadlich 4 , P. Krüger 4
.
1
1 , N.
, T. Niendorf
Department of Ophthalmology,
3 ,
S. Langner 4
University of Rostock, Rostock, Germany; 2 Preclinical Imaging Research Group, University of
Rostock, Rostock, Germany; 3 Berlin Ultrahigh
Field Facility, Max-Delbrueck-Center for Molecular
Medicine, Berlin, Germany; 4 Institute for Diagnostic
Radiology and Neuroradiology, University of
Greifswald, Greifswald, Germany
5846 — C0032 Fusion of fundus images and MRI data of the human eye.
Sandro I. De
Zanet 1, 2 , C. Ciller
H. Kowal 1, 2 .
1
1, 4 , P. Maeder 4 , F. L. Munier 3 , J.
Ophthalmic Technology, ARTORG
Center for Biomedical Engineering Research,
Bern, Switzerland; 2 Ophthalmology, Inselspital
Bern, Bern, Switzerland; 3 Unit of Pediatric Ocular
Oncology, Jules Goning Eye Hospital, Lausanne,
Switzerland;
Switzerland
4 Department of Radiology, CHUV/
MIAL, Universite de Lausanne, Lausanne,
5847 — C0033 Relationships between Anterior
Visual Pathway Morphology, Ocular Physiology and Visual Function in Glaucoma.
Swarupa
Kancherla
Kim 1, 3
Chan 1, 2
, G. Wollstein 2
.
1
2 , I. P. Conner 2, 3 , L. C. Ho
, J. S. Schuman
1 , S.
2, 3 , K. C.
NeuroImaging Laboratory, Department of Radiology, University of Pittsburgh, Pittsburgh,
PA; 2 UPMC Eye Center, Eye and Ear Institute,
Ophthalmology and Visual Science Research
Center, Department of Ophthalmology, UPMC
Eye Center, Pittsburgh, PA; 3
Pittsburgh, PA *CR
Department of
Bioengineering, University of Pittsburgh,
5848 — C0034 Automatic magnetic resonance imaging segmentation of the eye based on
3D Active Shape Models.
Carlos Ciller 1, 2
S. I. De Zanet 2, 3 , A. Pica
, F. L. Munier 6
4 , J. Thiran
, J. H. Kowal
5, 1 , P.
,
Maeder
Cuadra
1
7, 1 .
1
1, 3 , M. Bach
Department of Radiology, CHUV/
MIAL, Université de Lausanne, Lausanne,
Switzerland; 2 Ophthalmic Technology Group,
ARTORG Center of University of Bern, Bern,
Switzerland; 3 Department of Ophthalmology,
Inselspital, Bern University Hospital, Bern,
Switzerland; 4 Department of Radiation Oncology,
Inselspital, Bern University Hospital, Bern,
Switzerland; 5 Signal Processing Laboratoy (LTS5),
École Polytechnique Fédérale de Lausanne (EFPL),
Lausanne, Switzerland; 6 Unit of Pediatric Ocular
Oncology, Jules-Gonin Eye Hospital, Lausanne,
Switzerland; 7 CIBM, Université de Lausanne
(UNIL), Lausanne, Switzerland
5849 — C0035 High specificity but low sensitivity of MRI for detection of retinal hemorrhages in non-accidental trauma.
Austin
P. Bell 1, 4 , M. Hood
. 1
1, 4 , A. F. Choudhri 1, 3 , J. I.
University of Tennessee Health Science Calzada 1, 2
Center, Memphis, TN;
Memphis, TN;
Memphis, TN
3
2 Charles Retina Institute,
Radiology, Le Bonheur Children’s
Hospital, Memphis, TN; 4 Hamilton Eye Institute,
5850 — C0036 Tract-specific analysis of visual stream structural connectivity in late-blind patients with retinitis pigmentosa.
Samantha I.
Cunningham 1 , J. D. Weiland 1 , N. Lepore 2 , Y. Chai 2
Biomedical Engineering, University
,
2
B. S. Tjan 3, 4 .
1 of Southern California, Los Angeles, CA;
Department of Radiology, Children’s Hospital Los
Angeles, Los Angeles, CA; 3 Neuroscience Graduate
Program, University of Southern California,
Los Angeles, CA; 4 Department of Psychology,
University of Southern California, Los Angeles, CA
5851 — C0037 Focusing Precision under
Different Magnification Settings in Operating
Microscope with Coherent Image Coupling.
Vladimir Lemberg.
Abbott Medical Optics Inc.
,
Santa Ana, CA *CR
5852 — C0038 Optimizing Laser Parameters for Pump-Probe Microscopy of Conjunctival
Melanocytic Lesions.
Vora 1 , S. Deb
J. Cummings 3
2
Lejla Vajzovic
, J. W. Wilson 2
, P. Mruthyunjaya 1
1 , G. K.
, F. E. Robles 2 , T.
, W. Warren 2
1
.
Ophthalmology, Duke University Eye Center,
Durham, NC; 2
Durham, NC;
Durham, NC
3
Chemistry, Duke University,
Pathology, Duke University,
5853 — C0039 Cell Level Imaging of
Photoreceptors with Retinitis Pigmentosa using Differential Interference Contrast
Microscopy.
SeokHwan Kim 1 , J. Oh 2, 3 , S. Lee 2 , K.
Park 4 , H. Yu 4 2 , T. Lee 2
J. Kim 2 .
1
, S. Jun 3 , C. Kim
Hospital, Seoul, Republic of Korea; 2
, M. Seo 2 ,
Department of Ophthalmology, Boramae
Sensor
System Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of
Korea; 3 School of Mechanical Engineering, Yonsei
University, Seoul, Republic of Korea; 4 Department of Ophthalmology, Seoul National University
Hospital, Seoul, Republic of Korea
5854 — C0040 Watching dying RGC-5 cells by using Raman microscopy 2.
Takeshi
Morimoto 1
T. Fujikado
, H. Kanda
1 .
1
1 , T. Endo 2 , K. Nishida 2
Applied Visual Science,
Osaka Univ Graduate Sch of Med, Suita,
,
Japan; 2 Ophthalmology, Osakauniv Graduate Sch of
Med, Suita, Japan
5855 — C0041 Scanning Electron Microscope and Epiretinal Membranes in Vitreoretinal
Surgery.
Claudio Azzolini 1 , T. Congiu 2 , S.
Donati 1 , P. Basso
G. Airaghi 1
2 , S. Battistini 1 , R. Vinciguerra 1 ,
.
1 Dept. of Surgical and Morphological
Sciences - Section of Ophthalmology, Univerity of Insubria, Varese, Italy; 2 Dept. of Surgical and
Morphological Sciences - Section of Human
Anatomy, University of Insubria, Varese, Italy f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
383

Thursday Posters 8:30 am – 10:15 am
5856 – 5875 – Thursday – Posters
5856 — C0042 Signal Processing in High
Resolution Ultrasonic Imaging of Tissue
Characterization and Perfusion of the
Choroid.
D Jackson Coleman 1 , R. H. Silverman 1, 2
M. J. Rondeau 3 , S. Chang 1 .
1 Ophthalmology,
Columbia University Medical Center, New York,
,
NY; 2 F.L. Lizzi Center for Biomedical Research,
Riverside Research, New York, NY; group, New York, NY
3 the selfsimilar
5857 — C0043 Quantitative Ultrasonography of Vitreous Correlates with Contrast Sensitivity in Patients with Floaters.
Christianne A.
Wa 1, 2 ,
K. M. Yee 1, 2 , J. Mamou 3 , R. H. Silverman 3, 4 ,
J. Gale 2 , A. K. Ganti 1, 2 , J. A. Ketterling 3 , A. A.
Sadun 2 , J. Sebag 1 . 1 VMR Institute, Huntington
Beach, CA; 2 Ophthalmology, Doheny Eye Institute,
Los Angeles, CA; 3 Frederic L. Lizzi Center for
Biomedical Engineering, Riverside Research, New
York, NY; 4 Ophthalmology, Harkness Eye Institute,
College of Physicians & Surgeons, Columbia
University, New York, NY
5858 — C0044 Axial length comparison between two ultrasound devices and a partial coherence interferometry device.
Hang Tran
K. Yum
Sayegh 2
2, 4
.
Pomona, CA;
IL; 3
Illinois, Champaign, IL
1 ,
1
, J. Taibl 2, 4 , D. Hjelmstad 2, 3 , S. I.
Western University of Health Sciences,
2 The Eye Center, Champaign,
Arizona State University, Phoenix, AZ; 4 U of
5859 — C0045 Quantitative assessment of choroidal melanoma response to gamma knife radiosurgery (GKR) treatment with contrast-enhanced ultrasound (CEUS): preliminary results.
Maura Di Nicola 1, 2 , E.
Miserocchi 1 , M. Venturini 1 , C. Colantoni 1 , A.
Del Maschio 1 , R. Ratiglia 2 , F. Bandello 1 , G.
Modorati 1 .
1 Ophthalmology, University Vita-
Salute - Scientific Institute San Raffaele, Milan,
Italy; 2 Clinical Sciences and Community Health,
University of Milan, Milan, Italy
5860 — C0046 Ultrasound Biomicroscopic
Diagnosis Of Ciliary Body Cysts And Evaluation
Of Their Effect On Anterior Chamber
Angle.
Giorgia Maraone, G.
Mannino, S.
Calafiore,
C.
Mannino, M.
Delle Fave , L.
Spadea , E.
M.
Vingolo.
Ophtalmology , Sapienza university of
Rome , Rome , Ital y
5861 — C0047 Automatic detection of reticular drusen using multimodal retinal image analysis.
Mark J.
van Grinsven 1 ,
G. H. Buitendijk 2, 3 , C. Brussee 2, 3 , B. van
Ginneken 1 , T. Theelen 4 , C. C. Klaver 2, 3 , C. I.
Sanchez 1 . 1 Diagnostic Image Analysis Group,
Radboud University Medical Center, Nijmegen,
Netherlands; 2 Department of Ophthalmology,
Erasmus Medical Center, Rotterdam,
Netherlands; 3 Department of Epidemiology,
Erasmus Medical Center, Rotterdam,
Netherlands; 4 Department of Ophthalmology,
Radboud University Medical Center, Nijmegen,
Netherlands *CR
5862 — C0048 Peripheral Retinal Hemorrhages on Fundus Photography in Patients with
Suspected Abusive Head Trauma.
Pavlina S.
Kemp
Walz 4
1 , S. Q. Longmuir
, R. Oral 2
1, 2 , B. Zimmerman 3
, M. D. Abramoff 1
Ophthalmology, University of Iowa, Iowa City,
IA; 2 of Iowa, Iowa City, IA;
.
1
, A.
Department of
Department of Pediatrics, University of Iowa,
Iowa City, IA; 3 College of Public Health, University
4 College of Medicine,
University of Iowa, Iowa City, IA
5863 — C0049 Thermal Index in Ex
Vivo Bovine Lenses from Acoustic-Radiation-
Force Impulse (ARFI) Pulse Imaging.
Michele D.
Lee, R.
Urs, L.
H.
Suh, R.
H.
Silverman.
Harkness
Eye Institute, Columbia University , New York , NY
5864 — C0050 Reflection-based Imaging of
Macular Pigment Distributions in Infants and
Children.
Mohsen Sharifzadeh
P. S. Bernstein 2 .
1 Physics and astronomy, Univ. of Utah, Salt Lake City, UT;
1 , W. Gellermann
2 Department of
Ophthalmology and Visual Sciences, Moran Eye
Center, Salt Lake City, UT
1 ,
5865 — C0051 Smallest Needle and
Vitrectomy Trochar/Plug Sizes Identified on
X-Rays: To Avoid Unnecessary Radiation and Operating Room Turnover Time.
Yigit
Akduman 1 , J. Azhar 2 , T. Allam 1 , E. I. Akduman 1 ,
L. Akduman 3 .
1 Radiology, Saint Louis University,
St. Louis, MO; 2 Optometry, Illinois College of
Optometry, Chicago, IL; 3 Ophthalmology, Saint
Louis Univerisity, St. Louis, MO
5866 — C0052 Multimodal Evaluation
Of Patients With Chronic Central Serous
Chorioretinopathy.
Pedro M.
Leão , L.
F.
Barroso, R.
C.
Siqueira , R.
Jorge.
ophthalmology, universidade de Sao Paulo - USP-RP, Ribeirao
Preto, Brazil
5867 — C0053 The Effect of Photodynamic
Therapy on Short-Wavelength Fundus
Autofluorescence in Eyes with Acute Central
Serous Chorioretinopathy.
Stefan Hagen 1, 2 , S.
Ansari-Shahrezaei 1, 2 , E. Smretschnig 1, 2 , I. Krebs 1, 2 ,
C. G. Glittenberg 1, 2 , S. Binder 1, 2 . 1 Ophthalmology,
Rudolf Foundation Clinic, Vienna,
Austria; 2 Ophthalmology, Ludwig Boltzmann
Institute for Retinology and Biomicroscopic Laser
Surgery, Rudolf Foundation Clinic, Vienna, Austria
5868 — C0054 Usefulness of Ultra-Widefield
Fluorescein Angiography by Oral Administration of Fluorescein.
Masahiko Sugimoto , H.
Matsubara, R.
Miyata , Y.
Matsui , A.
Ichio, M.
Kondo.
Ophthalmology, Mie University School of
Medicine , Tsu, Japan f
5869 — C0055 Autofluorescence-Based
Macular Pigment Measurements before and after Cataract Surgery in a Large
Subject Population.
Akira Obana
Gohto 1 , T. Seto 1 , T. Ueno 3
1, 2 , Y.
, M. Sharifzadeh 4 , W.
Ophthalmology, Seirei Hamamatsu Gellermann 4 .
1
Gen Hosp, Hamamatsu, Japan; 2 Medical
Spectroscopy, Applied Medical Photonics
Laboratory, Medical Photonics Research Center,
Hamamatsu University School of Medicine,
Hamamatsu, Japan; 3 Optic Development,
R&D Devision, NIDEK CO.,LTD, Gamagori,
Japan; 4 Physics and Astronomy, University of Utah,
Salt Lake City, UT *CR
5870 — C0056 Autofluorescence and Red
Reflectance Imaging of Choroidal Nevus
Using Ultra-Wide-Field Scanning Laser
Ophthalmoscope.
Laura N. Distefano 1 , M. A.
Zapata 1, 3 , M. Leila 2 , T. Teixido 3 , A. Salas Torras 1 , J.
Rigo 1 , J. Garcia-Arumi 1, 4 .
1 Ophthalmology, Hospital
Vall d’Hebron, Barcelona, Spain; 2 Research
Institute of Ophthalmology, Giza, Egypt; 3 Institut d’Oftalmologia Clínica Girona, Girona,
Spain; 4 Instituto de Microcirugía Ocular, Barcelona,
Spain
5871 — C0057 Fundus Autofluorescence in Acute Retinal Necrosis.
Ashvini Reddy.
Ophthalmology, University of Virginia,
Charlottesville, VA
5872 — C0058 Scotopic and photopic dissociation in patients with chronic central serous chorioretinopathy.
Jakob Wågström , M.
Larsen . Glostrup Hospital , Glostrup , Denmar k
5873 — C0059 Imaging of Retinal
Vascular Disease Using Hypoxia-Sensitive
Contrast Agents.
. 1
Stephanie M.
Evan s 1 , A.
Ophthalmology and Visual Sciences, Jayagopal 1, 2
Vanderbilt Eye Institute, Nashville, TN;
Physiology and Biophysics, Vanderbilt University
Medical Center, Nashville, TN
2 Molecular
5874 — C0060 Evaluation Of Multicolor
Spectral Reflection Imaging (488 nm, 536 nm & 786 nm) In Comparison With Color
Photography, Autofluorescence And Spectral
Domain OCT imaging In A Consecutive Series
Of Patients With Retinal Disorders.
Simone
Kellner 1, 2 , S. Weinitz 1, 2 , G. Farmand 1 , U.
Kellner 1, 2 .
1 Rare Retinal Disease Center,
AugenZentrum Siegburg, MVZ ADTC Siegburg
GmbH, Siegburg, Germany; 2 RetinaScience, Bonn,
Germany
5875 — C0061 Normal values of retinal sensitivity determined by Macular Integrity
Assessment.
Manabe 2
F. Shiraga 1 .
1
Atsushi Fujiwara
, S. Izumibata 2
1 , C. Shiragami 2
, A. Murata 2
Kagawa University, Miki-cho,
Japan *CR
, S.
, Y. Morizane 1 ,
Okayama University Hospital,
Okayama, Japan; 2
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
384

Thursday – Posters – 5876 – 5898
5876 — C0062 Fundus-screening with
Optos ultra-widefield retinal imaging versus biomicroscopy in patients with pneumological diseases.
Timo Bullmann 1
Schiel 1
Darida
, M. Schumann
1 , B. Lorenz 1 .
1
2
2 , E. Wimmer
, J. Post 2
, H.
, M. Andrassi-
Ophthalmology, Justus Liebig
University Giessen, Giessen, Germany; 2 Medical
School, Justus Liebig University Giessen, Giessen,
Germany *CR
5877 — C0063 Assessing the incidence of ocular dicrotism in healthy and glaucomatous eyes.
Monika E.
Danielewska 1 , P. Krzyzanowska-
Berkowska 2 , D. Iskander 1 . 1 Institute of
Biomedical Engineering & Instrumentation,
Wroclaw University of Technology, Wroclaw,
Poland; 2 Department of Opthalmology, Wroclaw
Medical University, Wroclaw, Poland *CR
5878 — C0064 Clinical Applications of
Multiwavelength Scanning Laser Imaging.
Daren
Hanumunthadu , M.
Clemo, D.
A.
Sim, P.
A.
Keane,
P.
J.
Patel.
NIHR Moorfields Biomedical Research
Centre , Moorfields Eye Hospital NHS Foundation
Trust and UCL Institute of Ophthalmology, London ,
United Kingdom *CR
5879 — C0065 A Case of Occult Macular
Dystrophy with Foveal Detachment by
Vitreomacular Traction.
Yu Kato 1 , K. Fujinami 1, 2 ,
T. Noda 1 , M. Akahori 1 , T. Iwata 1 , Y. Miyake 1, 3 ,
K. Tsunoda 1 .
1 National Institute of Sensory
Organs, National Tokyo Medical Center, Tokyo,
Japan; 2 Ophthalmology, Keio University School of
Medicine, Tokyo, Japan; 3 Aichi Medical University,
Aichi, Japan
5880 — C0066 Spectral Domain Optical
Coherence Tomography in Lipemia
Retinalis.
Omar Shakir , S.
Grover . Ophthalmology,
University of Florida - Jacksonville , Jacksonville ,
FL
5881 — C0067 Vertical midline respecting ganglion cell layer defect in patients with space-occupying brain lesion.
Ahreum Chung, Y.
Kim, N.
Kim.
Inha University Hospital , Incheon,
Republic
M. Jardel 2 of Korea
5882 — C0068 Telemedicine as a useful tool for referrals to eye care services in a remote city of the Brazilian Amazon.
P. H. Morales 1
Mariana D. Coelho 1
, S. R. Salomao 1 , I. Lins da Silva 1
, M. Giordani Mileo
L. Marcelo Aranha 2 .
1
,
,
Federal University of Sao
Paulo, São Paulo, Brazil; 2
2 , R. Belfort, Jr.
1
,
Institute of Biomedical
Research, Montenegro ICB5/USP, Montenegro,
Brazil
5883 — C0069 EyeArt: Advanced
Image Analysis Tools for Diabetic
Retinopathy Screening and Telemedicine
Applications.
Kaushal Solanki 1 , S. Bhat 1 , C.
Ramachandra 1 , M. Nittala 2 , S. R. Sadda 2 .
1 Eyenuk
LLC, Woodland Hills, CA; 2 Ophthalmology, USC
Keck School of Medicine, Los Angeles, CA *CR
5884 — C0070 Giving Greater Access to
Retinal Screening Through Low-cost, Easy-
To-Use Non-Mydriatic Retinal Cameras in
Underserved Clinics.
Johnson 1 , E. Barriga
G. Zamora 1 . 1
San Antonio, TX *CR
Peter Soli z 1
, W. Bauman
VisionQuest Biomedical LLC,
Albuquerque, NM; 2
, J. Maynard
1 , S. C. Nemeth 1
Retina Institute of South Texas,
Exhibit/Poster Hall SA C0071-C0084
1 , R.
Thursday, May 08, 2014 8:30 AM-10:15 AM
2 ,
Retina / Multidisciplinary Ophthalmic Imaging /
Retina
Moderator: Eric H. Souied
5885 — C0071 Outer Retinal Tubulation as a Predictor of the Growth Rate of
Geographic Atrophy in Age-related Macular
Degeneration.
Nittala
Henry 2
1 , S. R. Sadda
.
1
Amirhossein Hariri
1 , E. C. Strauss
1
2
, M. G.
, P. Lai 2 , E.
Doheny Eye Institute, Los Angeles, CA;
2 Genentech Inc., South San Francisco, CA *CR
5886 — C0072 Multimodal Imaging Of Ghosts
In Geographic Atrophy Areas.
Eric H.
Souied ,
C.
Bonnet , H.
Oubraham , R.
Blanco Garavito ,
N.
Puche, J.
Zerbib , G.
Querques . Retina Creteil,
University Paris Est, Creteil, France *CR
5887 — C0073 Choroidal thickness in geographic atrophy associated with agerelated macular degeneration.
Moritz Lindner 1
J. Czauderna 1
Brinkmann 1
, A. Bezatis 1
, R. Fimmes 2
, E. Becker 1
, S. Schmitz-Valckenberg
, M. Fleckenstein 1 .
1
, C. K.
,
1 ,
F. G. Holz 1 Department of
Ophthalmology, University of Bonn, Bonn,
Germany; 2 Institute for Medical Biometry,
Informatics and Epidemiology, University of Bonn,
Bonn, Germany *CR , f
5888 — C0074 Long-term natural history of geographic atrophy in age-related macular degeneration.
Steffen Schmitz-Valckenberg, M.
Fleckenstein , M.
Lindner, A.
P.
Goebel , F.
G.
Holz . Ophthalmology, University of Bonn , Bonn ,
Germany *CR, f
5889 — C0075 Structural characteristics of retinal layers adjacent to Geographic
Atrophy.
Mohammad A.
Sadiq, N.
Rajagopalan,
K.
E.
Guinn, M.
S.
Hanout , L.
J.
Zapata , J.
Maya ,
S.
Sarwar , D.
V.
Do , Q.
Nguyen , Y.
Sepah.
Ocular
Imaging Research and Reading Center, Stanley
M. Truhlsen Eye Institute. University of Nebraska
Medical Center, Omaha, NE *CR
5890 — C0076 Intravitreal Erythropoietin in Eyes with Geographic Atrophy Secondary to Age-related Macular Degeneration.
Stephen
H.
Sinclair
Presti 3 . 1
1, 2
Media, PA; 2
, K. Hurley 1 , B. Parvus
School Medicine, Philadelphia, PA;
1 , P.
Ophthalmology, Sinclair Retina Associates,
Ophthalmology, Drexel University
3 Interactive
Multi-media Technology Center, Georgia Institute of Technology, Atlanta, GA *CR
5891 — C0077 Choroidal thickness changes in progressing geographic atrophy secondary to age-related macular degeneration.
Elisabetta
Pilotto
Evelyn
Italy; 2
1
2
, F. Guidolin 1 , E. Convento 1
, R. Parrozzani 2 , E. Midena
, F. Stefanon 1
1, 2 .
1
, L.
Department of Ophthalmology, University of Padova, Padova,
G.B. Bietti Foundation, IRCCS, Rome, Italy
5892 — C0078 Intravitreal Sirolimus for the Treatment of Bilateral Geographic
Atrophy Associated with Age-Related Macular
Degeneration: Results of a Phase I/II Trial.
Philip A. Petrou 1 , K. Shimel 2 , C. A. Cukras 2 , F. L.
Ferris 2 , E. Y. Chew 2 , W. T. Wong 1 . 1 Unit on Neuron-
Glia Interactions in Retinal Disease, National
Eye Institute, National Institutes of Health (NIH),
Bethesda, MD; 2 National Eye Institute, National
Institutes of Health (NIH), Bethesda, MD f
5893 — C0079 Retinal oximetry in eyes with geographic atrophy due to age-related macular degeneration.
Andreas Pollreisz, M. Baratsits,
K. Kefer, C. Mitsch, S. Sacu, U. Schmidt-Erfurth.
Ophthalmology, Medical University Vienna,
Vienna, Austria
5894 — C0080 Rates of Vision Loss in
Patients with Geographic Atrophy in AREDS and AREDS 2.
David Valent 1 , E. Y. Chew 1 ,
E. Agron 1 , F. L. Ferris 1 , P. J. Rosenfeld 3 , T. E.
Clemons 2 , W. T. Wong 1 , A. Disease Study Research
Group 2 . 1 National Eye Institute/National Institutes of Health, Bethesda, MD; 2 EMMES Corporation,
Rockville, MD; 3 Bascom Palmer Eye Institute,
Miami, FL f
5895 — C0081 Spectral-domain Optical
Coherence Tomography Features of Regions of Increased Autofluorescence at the Margin of Geographic Atrophy in Patients with Age
Related Macular Degeneration.
Hariri
P. Lai 2
1 , M. G. Nittala 1
, S. R. Sadda 1, 3
Los Angeles, CA;
Francisco, CA;
2
.
, E. C. Strauss 2
1
Yan Lu o 1 , A.
, E. Henry
Doheny Eye Institute,
Genentech, Inc., South San
2
3 Department of Ophthalmology,
University of Southern California, Los Angeles,
CA *CR
,
5896 — C0082 Correlation between Fundus
Autofluorescence and Spectral Domain Optical
Coherence Tomography Measurements in
Geographic Atrophy.
Muneeswar Gupta Nittala 1 ,
A. Hariri 1 , E. Henry 2 , E. C. Strauss 2 , P. Lai 2 , S. R.
Sadda 1 .
1 Ophthalmology, Doheny Eye Institute, Los
Angeles, CA; 2 Genentech, Inc, South San Francisco,
CA *CR
5897 — C0083 The Autofluorescence in the
Detection and Monitoring of Behavior Patterns
Age-Related Macular Disease (ARMD) Dry
Type.
Milagros Velazco, J. Rodriguez. RETINA,
Conde de Valenciana, Mexico DF, Mexico f
5898 — C0084 MultiColor imaging in the evaluation of geographic atrophy due to agerelated macular degeneration.
Naima Ben
Moussa , A.
Georges, E.
H.
Souied , G.
Querques .
Ophthalmology, University Paris Est Creteil, Centre
Hospitalier Intercommunal de Creteil, Creteil,
France f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
385

Thursday Posters 8:30 am – 10:15 am
5899 – 5919 – Thursday – Posters
Exhibit/Poster Hall SA C0085-C0121
Thursday, May 08, 2014 8:30 AM-10:15 AM
5902 — C0088 Dark-Rearing (DR) Mitigates
Pre-Retinal Neovascularization and OIR
Pathology with no Detriment To Visual Function and Morphology: Compelling Evidence For DR as Non-Invasive Intervention in Retinopathy of Prematurity (ROP).
Tailoi Chan-Ling 1 ,
S. Adamson
Koina
Linsenmeier
1
4 , P. Hu
5
, R. Natoli 2
1 , J. C. Lau
, R. Maccarone
5 , J. M. Provis 2
3 , M.
& Histology, University of Sydney, Sydney, NSW,
Australia; 2
, S. Bisti 3
, R. A.
.
1 Department of Anatomy
ARC Centre for Excellence in Vision
Science, Australian National University, Canberra,
ACT, Australia; 3 Biomedical & Science Technology,
The University of LAquila, LAquila, Italy; 4 ACT
Pathology, The Canberra Hospital, Canberra, ACT,
Australia; 5 Department of Biomedical Engineering,
Northwestern University, Evanston, IL
5905 — C0091 Telemedicine for ROP
Screening.
Michael T. Trese 1, 2 , K. Drenser 1, 2
Capone 1, 2
Oak, MI; 2
MI *CR
.
1
, A.
Associated Retinal Consultants, Royal
William Beaumont Hospital, Royal Oak,
5907 — C0093 Outcomes of laser treatment in infants with high-risk pre-threshold retinopathy of prematurity (ROP) in East London.
Marina
Vasalaki 1 , S. Khan 1 , S. Karim
Patel 1, 2 , M. Reddy 1 .
1
1 , G. Adams 2 , H.
Ophthalmology, Barts Health
NHS Trust - The Royal London Hospital, London,
United Kingdom; 2 Ophthalmology, Homerton
University Hospital, London, United Kingdom
5912 — C0098 Characterizing the Natural
History of Retinopathy in Incontinentia
Pigmenti.
Connie Chen , I.
Han, M.
F.
Goldberg .
Wilmer Eye Institute, Baltimore, MD
Retina
Moderators: Michael T. Trese and
Michael F. Chiang
5899 — C0085 Ocular and Systemic
Adverse Events Asociated with Intravitreal
Bevacizumab in the Treatment of Retinopathy of
Prematurity.
Victoria Gonzalez 1 , A. Kychenthal 3 ,
P. Dorta 3 , A. Banker 2
Martinez-Castellanos
D.F., Mexico;
Mexico; 2
2
Ahmedabad, India;
Rio, Santiago, Chile
V. Morales-Canton 1
3
, V. Morales-Canton
1 . 1 by the iPhone 5 camera.
Rafael
, R. Chan 2
M. A. Martinez-Castellanos
College, New York, NY;
University, Portland, OR
3
1 .
*CR
1
Romero
1 , M. A.
Retina, APEC, Mexico,
Retina, Banker, Navrangpura,
Retina, Hospital Roberto del
5900 — C0086 Long-Term Safety and
Efficacy of Intravitreal Bevacizumab (IVB) for
Aggressive Posterior Retinopathy of Prematurity
(AP-ROP).
Pankaj Malhotra , K.
Kishore.
Surgery,
University of Illinois College of Medicine , Peoria ,
Peoria , IL
5903 — C0089 Interexpert agreement in the diagnosis and management of Retinopathy of Prematurity using digital images acquired
Vera
, M. F. Chiang 3
Retina, Asoc
,
1 ,
Para Evitar la Ceguera en Mexico, Mexico, D.F,
Ophthalmology, Weill Cornell Medical
Ophthalmology and
Medical Informatics & Clinical Epidemiology,
Casey Eye Institute at Oregon Health & Science
5904 — C0090 Does the Replacement of Foetal
Haemoglobin by Adult Haemoglobin After
Blood Transfusion in Very Preterm Infants
Contribute to the Development of Retinopathy of
Prematurity? A Prospective Cohort Study.
Chris
Stutchfield 1, 2 , D. Odd 2
R. Markham 3
Kingdom; 3
, A. Jain 1
.
1
, C. Williams 3, 1 ,
Neonatal unit, St. Michael’s
Hospital, Bristol, United Kingdom; 2
Ophthalmology, Bristol Eye Hospital,
Bristol, United Kingdom
Neonatal unit, Southmead Hospital, Bristol, United
5906 — C0092 Increasing severity of ROP after birth correlates with the level of functional and morphological retinal alterations at primary school age.
Birgit Lorenz , M.
Andrassi Darida ,
C.
Ophthalmology, Linköping University, Linköping,
Sweden; 4 Division of Ophthalmology, Department of clinical sciences, Umeå university, Umeå,
Sweden;
University Hospital, Lund, Sweden;
Hospital, Stockholm, Sweden
5909 — C0095 Risk Factors for Development of Zone I versus Zone II Retinopathy of
Prematurity: A Retrospective Analysis of the
Early Treatment of Retinopathy of Prematurity
Study (ET-ROP).
Mynna Ishikiriyama 1, 2
A. Levison 1, 3
,
Campomanes 1
, M. Deiner
.
1
1 , A. G. de Alba
Ophthalmology, University of California-San Francisco, San Francisco,
CA; 2 Ophthalmology, Santa Casa of Sao Paulo, Sao
Paulo, Brazil; 3 Ophthalmology, Cole Eye Institute,
Cleveland Clinic, Cleveland, OH *CR
5910 — C0096 Efficacy of oral acetazolamide and topical dorzolamide therapy for X-linked juvenile retinoschisis maculopathy.
Maria Silvana
Galantuomo 1 , A. Cuccu 1 , I. Zucca 1 , M. N. Preising 2 ,
B. Lorenz 2 , M. Fossarello 1 .
1 Ophthalmology,
R.
Friedburg,
Italy; 2 Ophthalmology, University of Giessen,
Henr
Murray 3 y 1
5
M.
Ophthalmology,
Giessen,
Bokun,
Justus
Germany
Department of Ophthalmology, Lund
Giessen, Germany
, R. Sisk 2
*CR
-
, A. M. Berrocal 1
, J. Tzu
K.
. 1
1
Stieger,
Liebig
Academy, Gothenburg, Sweden;
University of Cagliari, Cagliari,
Diseases: Extended Follow Up.
Palmer Eye Institute, Miami, FL;
3
Christopher
2
6
W.
Department of
St. Erik’s Eye
, T. A. Albini 1
Ocular Oncology and Retina, Miami, FL
Bowl
University
, T. G.
Cincinnati Eye Institute, Cincinnati, OH; 3
.
Giessen,
5911 — C0097 Intravitreal Bevacizumab for
Ophthalmology,
Murray
5908 — C0094 Evaluation of new guidelines for ROP screening in Sweden with the help of a national quality register - SWEDROP.
Gerd
Holmstrom 1 , A. Hellström 2 , P. Jakobsson 3 , P.
Lundgren 4 , K. Tornqvist 5 , A. Wallin 6 . 1 Neuroscience, ophthalmology, Uppsala University, Uppsala,
Sweden; 2 Section of Pediatric Ophthalmology,
The Queen Silvia Children’s hospital, Sahlgrenska the Treatment of Pediatric Retinal and Choroidal
Ophthalmology, Bascom
5913 — C0099 Normative data for intraocular pressure and central corneal thickness in preterm infants.
S.
A.
of
Grover
Patel,
. Ophthalmology,
Jacksonville , FL
Wassia Khaja,
Retinopathy of Prematurity.
K.
V.
University
Chalam of
5914 — C0100 Comparing Outcomes and Complication Rates with Intravitreal
,
Florida,
Bevacizumab versus Laser Therapy for Type 1
5919 — C0105 Retinal Fluorescein
Angiographic Features In The Different Stages
Of Retinopathy Of Prematurity.
Maria G.
Martinez , L.
Rodriguez Quiñones , V.
Morales-
Canton , M.
A.
Martinez Castellanos.
Retina ,
Asociacion Para Evitar la Ceguera en Mexico , San
Lucas Coyoacan , Mexico
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
K.
J. Wang 1 .
Ferenchak,
Medical Center
Bevacizumab.
1
Prematurity.
Baldascino
Department the Sacred of
,
,
Ophthalmology, Indiana University,
Indianapolis, IN;
L.
2
Heart,
J.
Southwest, Dallas, TX
A.
Chicago,
Emanuele
Orazi,
Tonti,
S.
Rome ,
Ophthalmology,
Ital
Rebecca Deutsch,
Cohen.
IL
D.
Luceri y
Kathryn M. Haider
Rush
,
1
F.
5916 — C0102 Refractive Error and Visual
Acuity in infants with ROP treated with
, E. Birch
Retina Foundation of the
Lepore ,
Molle.
Catholic
2 ,
5918 — C0104 Effect of sunlight exposure during pregnancy on Retinopathy of
H.
University
5915 — C0101 The teaching and practice of retinopathy of prematurity screening skills during Ophthalmology residency training: a nationwide survey.
Talía Nieto, R.
Romero Vera ,
M.
A.
Martinez Castellanos.
APEC , Mexico City ,
Mexico
5917 — C0103 Neonatal serum cytokine profiles with and without retinopathy of prematurity.
Syatirah Abu Yazi b 1 , R. Mohd
Salleh 2 , N. Khaliddin 1, 3 , Y. Choo 4 , A. Ahmad
Kamar 4 , S. Sulaiman 5 , M. Choo 1, 3 , C. K. Patel 6 ,
T. A. Kamalden 1, 3 . 1 Uni Malaya Eye Research
Centre, University of Malaya, Kuala Lumpur,
Malaysia; 2 School of Health Sciences, Science
University of Malaysia, Kubang Kerian,
Malaysia; 3 Department of Ophthalmology,
University of Malaya, Kuala Lumpur,
Malaysia; 4 Department of Paediatrics, University of
Malaya, Kuala Lumpur, Malaysia; 5 Department of
Obstetrics and Gynaecology, University of Malaya,
Kuala Lumpur, Malaysia; 6 Oxford Eye Hospital,
John Radcliffe Hospital, Oxford, UK, United
Kingdom
University
386

Thursday – Posters – 5920 – 5938
5920 — C0106 Evaluating, monitoring and predicting visual acuity during the first two years of life in premature infants with and without
Retinopathy of Prematurity using an indigenous normogram.
Anand Vinekar, P.
Hari , A.
Zope , V.
Kemmanu, M.
Kurian , B.
Shetty . Pediatric Retina ,
Narayana Nethralaya Postgraduate Institute of
Ophthalmology, Bangalore, India
5921 — C0107 Correlation of Severity of
Retinopathy of Prematurity and the Size of the Infant’s Electronic Medical Record.
Reid
Mollman, J.
Cao, R.
W.
Enzenauer, E.
McCourt,
R.
Braverman, M.
Paciuc Beja . Ophthalmology,
University of Colorado , Aurora , CO
5922 — C0108 Anti-Vascular Endothelial
Growth Factor (VEGF) for Retinopathy of Prematurity: Jules Stein Eye Institute
Experience.
Ryan K.
Wong , I.
Tsui .
Ophthalmology, Jules Stein Eye Institute, Los
Angeles, CA
5923 — C0109 Intravitreal Anti-Vascular
Endothelial Growth Factor inhibitors in
Treatment of Retinopathy of Prematurity:
Systematic Review.
Parisa Emami-naeini .
Ophthalmology, Kresge Eye Institute, Detroit, MI
5924 — C0110 Fluorescein Angiography
Differences Between Retinopathy of Prematurity and Retinopathy Induced by Oxygen in Preterm
Newborns.
Alan Alba Orozco , L.
Rodriguez
Quiñones , H.
Sepulveda, V.
Morales-Canton , M.
A.
Martinez Castellanos.
Retina , Assoc Para Evitar la
Ceguera en Mexico , IAP, Mexico , Mexico
5925 — C0111 The new modified technique of the cryotherapy and laser photocoagulation of the retina under the visual control of RetCam
3 in newborns with high-risk prethreshold
ROP.
Juraj Timkovič , J.
Němčanský, D.
Cholevík ,
P.
Mašek.
Clinic of Ophthalmology, University
Hospital Ostrava, Ostrava, Czech Republic
5926 — C0112 Comparison of Serum
Concentrations of Bevacizumab and Vascular
Endothelial Growth Factor (VEGF) Levels in Laser and Bevacizumab Treated ROP
Patients.
Lingkun Kong , A.
R.
Bhatt, A.
B.
Demny,
P.
G.
Steinkuller.
Ophthalmology, Baylor College of
Medicine , Houston, TX
5927 — C0113 A Computerized Telemedicine
System for Screening of Retinopathy of
Prematurity (ROP) and Validation of
ROPtool.
Ashkan Abbe y
D. C. Musch 2
Drenser 1 , D. K. Wallace 3
1
, C. Andrews
, C. G. Besirli 2
2 , A. Capone 1
, M. T. Trese 1 . 1
, P. P. Lee
, K. A.
Associated
Retinal Consultants, William Beaumont Hospital,
Royal Oak, MI; 2 Ophthalmology, University of Michigan - Kellogg Eye Center, Ann Arbor,
MI; 3 Ophthalmology, Duke University, Durham,
NC *CR
2 ,
5928 — C0114 Patients with retinopathy of prematurity (ROP) have increased levels of prolactin and reduced levels of vasoinhibins in the circulation.
Vazquez Membrillo Miguel
Ange l 1 , L. Zepeda Romero
J. Gutierrez Padilla
Barrera de Leon
Chalita 2
3
2 , F. Gomez Aguayo
2 , E. Angulo Castellanos
, C. Gonzalez Bernal 3
, A. Meza Anguiano 2 , C. Clapp 1
2
2 ,
, J.
, A. Quezada
.
1 Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico (UNAM), Campus Juriquilla,
Mexico; 2 OPD, Hospital Civil “Fray Antonio
Alcalde”, Centro Universitario de Ciencias de la
Salud,Universidad de Guadalajara, Guadalajara,
Mexico; 3 Hospital Mateno Infantil “Esperanza
López Mateos” Secretaria de Salud Jalisco,
Guadalajara, Mexico
5929 — C0115 Functional modifications of retinal images in quantitative plus disease diagnosis of retinopathy of prematurity.
Samir
N.
Pate l 1
S. Ostmo
, R. Chan
Ataer-Cansizoglu 3
5
1 , A. Ruggeri
, M. F. Chiang 5, 6 . 1
2 , E. Poletti 2
, J. Kalpathy-Cramer 4
, E.
, K. Jonas
Ophthalmology,
Weill Cornell Medical College, New York,
PA; 2 Information Engineering, University of
Padova, Padua, Italy; 3 Electrical and Computer
Engineering, Northeastern University, Boston,
1 ,
MA; 4 Radiology, Massachusetts General Hospital,
Boston, MA; 5 Ophthalmology, Casey Eye Institute at Oregon Health & Science University, Portland,
OR; 6 Medical Informatics & Clinical Epidemiology,
Casey Eye Institute at Oregon Health & Science
University, Portland, OR *CR
5930 — C0116 Inter-reader Agreement and
Performance in Diagnosing ROP as Compared to a Gold Standard Diagnostic Algorithm.
Michael
C. Ryan 1 , S. Ostmo 2 , K. Jonas 4 , R. Chan 4 , M. F.
School of Medicine, Oregon Health Chiang 2, 3 .
1
& Science University, Portland, OR; 2 Department of Ophthalmology, Casey Eye Institute at
Oregon Health & Science University, Portland,
OR; 3 Department of Medical Informatics & Clinical
Epidemiology, Casey Eye Institute at Oregon Health
& Science University, Portland, OR; 4 Department of Ophthalmology, Weill Cornell Medical College,
New York, NY *CR
5931 — C0117 Vitreoretinal interface disorders assessed by SD-OCT in patients with retinopathy of prematurity.
Sarai Delgado-Pelayo,
V. González, V. E. Giordano, M. A. Martinez-
Castellanos. Retina, Asociación para Evitar la
Ceguera, México, Mexico
5932 — C0118 Evaluation of Spectral Domain
Optical Coherence Tomography Vascular
Characteristics in Subjects with Retinopathy of Prematurity.
Viet 1 , D. K. Wallace
Toth 1, 3 . 1
Ramiro
1, 2
Ophthalmology, Duke University Eye
Center, Durham, NC; 2
S.
Maldonad
, S. F. Freedman
School of Medicine, Durham, NC; 3 o 1
1, 2
, D. Tran-
, C. A.
Pediatrics, Duke University
Biomedical
Engineering, Duke University, Durham, NC *CR
5933 — C0119 The Effect of Intravitreal
Bevacizumab on Cystoid Macular Edema
(CME) in Retinopathy of Prematurity (ROP) as
Detected by Handheld Spectral Domain Optical
Coherence Tomography (SDOCT).
Sailaja ( Sailu)
Bondalapati, J.
Ulrich , M.
T.
Cabrera.
University of
North Carolina , School of medicine , Chapel Hill ,
NC
5934 — C0120 Structural and vascular developmental changes of the fovea in patients with spontaneously regressed retinopathy of prematurity assessed by fluorescein angiography and spectral domain OCT.
Luvia Rodriguez
Quiñones , V.
E.
Giordano , S.
Salinas Longoria ,
V.
Morales-Canton , M.
A.
Martinez Castellanos.
Retina , Asociacion para Evitar la Ceguera en
Mexico , Mexico , Mexico
5935 — C0121 Spectral-Domain Optical
Coherence Tomography (Spectralis) and
Fundus Autofluorescence Findings in
Foveal Hypoplasia.
Kevin Cronin , S.
Grover .
Ophthalmology, University of Florida -
Jacksonville , Jacksonville , FL
Exhibit/Poster Hall SA C0167-C0185
Thursday, May 08, 2014 8:30 AM-10:15 AM
Retina / Anatomy/Pathology
Moderator: Emily Y. Chew
5936 — C0167 Morpho-functional long term evolution of dome shaped maculas.
Guillaume
Soudier
Strasbourg, France;
France
1
Bourcier 1
, V. Gualino
C. Speeg-Schatz 1 , R. Tadayoni
, D. Gaucher
2
2 , A. Gaudric
1
2
2 , P. G. Massin
, M. Nardin 1 , T.
.
1 NHC university hospital,
Lariboisière hospital, Paris,
2 ,
5937 — C0168 Prevalence of macular complications associated with high myopia: a prospective study in a clinical setting.
Olivier
Lichtwitz 1 , S. Rouissi
N. Leveziel 1 .
1
1 , M. Boissonnot
Ophthalmology, Poitiers, France; 2
1 , P. Ingrand
University Hospital Poitiers,
University
Hospital Poitiers, Public Health, Poitiers, France
2 ,
5938 — C0169 Longterm Follow up and
Role of Staphyloma Radius of Curvature in Cases of Spontaneous Improvement of
Myopic Foveoschisis.
Katherine Chen 1, 2 ,
C. Chen 1, 3 , J. Garcia-Arumi
Q. V. Hoang 1
University, New York, NY; 2
4 , S. Chang 1 ,
.
1 Ophthalmology, Columbia
Institute of Human
Nutrition, Columbia University, New York, NY;
3 Ophthalmology, Chang Gung Memorial Hospital,
Chiayi, Taiwan; 4 Ophthalmology, Hospital
Universitario Vall d, Barcelona, Spain *CR f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
387

Thursday Posters 8:30 am – 10:15 am
5939 – 5954 – Thursday – Posters
5939 — C0170 Comparison of Ocular
Axial Length Measurements with MRI and
Partial Coherence Interferometry in Highly
Myopic Patients with Posterior Staphyloma.
Jonathan Tang
Hoang 1 . 1
1 , J. Y. Pan 1, 2 , S. Chang 1 , Q. V.
Edward S. Harkness Eye Institute,
Columbia University College of Physicians and
Surgeons, New York, NY; 2 Methodist Girls’ School,
Singapore, Singapore *CR
5940 — C0171 Acute Macular
Neuroretinopathy Following Trauma.
Nicholas
D.
Chinskey , M.
W.
Johnson.
Ophthalmology and
Visual Sciences , University of Michigan ,
Ann Arbor, MI
5941 — C0172 Retinal topography of myopic eyes: A spectral domain optical coherence tomography study.
Seong-Woo Kim 1
Oh 2 , C. Yun 1 , K. Huh 1 . 1
, J. Oh 1 , I.
Ophthalmology, Korea
University, College of Medicine, Seoul, Republic of Korea; 2 Ophthalmology, Wonkwang University
Sanbon Hospital, Sanbon, Republic of Korea
5942 — C0173 Ocular risk factors for myopic foveoschisis.
Chang Ki Yoon , H.
Yu .
Ophthalmology, Seoul National University
Hospital , Seoul, Republic of Korea
5943 — C0174 Maculopathy in Patients with
Monoclonal Gammopathy of Undetermined
Significance.
Stephen J.
Smith, M.
W.
Johnson.
Kellogg Eye Center , University of Michigan ,
Ann Arbor, MI
5944 — C0175 Paraproteinemic maculopathy.
bachir abia d 1 , A. M. Mansour 1, 2 ,
J. Arevalo 3, 8 , H. Zegarra 4 , G. Shah 5 , R.
Moorthy 6 , J. S. Pulido 7 , R. Alameddine 1 , A. Bou
Ghannam 1 , G. The Collaborative Paraproteinemic
Maculopathy 1 .
1 Ophthalmology, American
University of Beirut Medical Center, Beirut,
Lebanon; 2 Ophthalmology, Rafic Hariri University
Hospital, Beirut, Lebanon; 3 Ophthalmology, Wilmer
Eye Institute, The Johns Hopkins University,
Baltimore, MD; 4 Retina Associates of Cleveland,
Beachwood, OH; 5 Barnes Retina Institute, St. Louis,
MO; 6 Ophthalmology, Indiana University School of
Medicine, Indianapolis, IN; 7 Ophthalmology, Mayo
Clinic, Rochester, MN; 8 Vitreoretinal Division, The
King Khaled Eye Specialist Hospital, Riyadh, Saudi
Arabia
5945 — C0176 Dome-shaped macula detachment: new treatment approach in 2 cases.
Gisele Soubrane 1 , N. Massamba 3 ,
C. M. Herpe 4
France; 2
.
1
, I. Aknin 2
University PARIS V, Paris,
Estivalière, Cannes, France;
PONTOISE, Cergy Pontoise, France;
Laval, France
3 CH CERGY
4 CHR Laval,
5946 — C0177 Correlating Changes In
Macular Function With Antomical Pathology
In Tractional Epiretinal Membrane.
Adil
Syed 1, 2 , T. Hong 1 , G. Broadhead 1, 2 , M. Zhu 1, 2 , A.
A. Chang 1, 2 .
1 Sydney Institute of Vision Science,
Sydney, NSW, Australia; 2 Save Sight Institute,
Sydney, NSW, Australia
5947 — C0178 High-resolution assessment of cone photoreceptor structure and function in macular telangiectasia type 2 (MacTel).
Qinyun
Wang 1 , W. S. Tuten 2 , B. J. Lujan 2 , J. Holland 1 ,
1
S. D. Schwartz 3 , J. L. Duncan 1 , A. Roorda 2 .
Ophthalmology, University of California,
San Francisco, San Francisco, CA; 2 School of
Optometry and Vision Science Graduate Group,
3
University of California, Berkeley, Berkeley, CA;
Jules Stein Eye Institute, University of California,
Los Angeles, Los Angeles, CA *CR , f
2
5948 — C0179 Patterns of retinal sensitivity loss in type 2 idiopathic macular telangiectasia
(MacTel).
Ferenc B. Sallo
Vujosevic 8, 3
Pauleikhoff 6 , T. Peto 4 .
1
1, 2
, T. E. Clemons 7
, I. Leung 2, 4 , S.
, A. C. Bird 5 , D.
Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom;
Research and Development, Moorfields Eye
Hospital, London, United Kingdom;
Italy; 4
3 Department of Ophthalmology, University of Padova, Padova,
5
NIHR Biomedical Research Centre at
Moorfields Eye Hospital and UCL Institute of
Ophthalmology, London, United Kingdom;
Inherited Disease, Moorfields Eye Hospital,
London, United Kingdom; 6 Department of
Ophthalmology, St Franziskus Hospital, Münster,
Germany; 7 The EMMES Corporation, Rockville,
MD; 8 The International Microperimetry Reading
Centre, Padova, Italy
5949 — C0180 A New Clinical Sign in
Parafoveal Telangiectasia.
Avinash Pathengay, A.
Jindal , H.
Choudhury.
Retina and Uveitis Services ,
L.
V.
Prasad Eye Institute, Vishakhapatnam , India
5950 — C0181 Characteristics of pigmented lesions in type 2 idiopathic macular telangiectasia (MacTel).
Irene Leung
B. Sallo 1, 3
Clemons 4
, D. Pauleikhoff
, T. Peto 5 .
1
6 , A. C. Bird
1, 5
2
, F.
, T. E.
Research and Development,
Moorfields Eye Hospital, London, United
Kingdom; 2 Inherited Disease, Moorfields Eye
Hospital, London, United Kingdom; 3 Cell Biology,
UCL Institute of Ophthalmology, London,
United Kingdom;
Rockville, MD; 5
4 The EMMES Corporation,
NIHR Biomedical Research
Centre at Moorfields Eye Hospital and UCL
Institute of Ophthalmology, London, United
Kingdom; 6 Department of Ophthalmology, St
Franziskus Hospital, Münster, Germany
5951 — C0182 Non-invasive evaluation of microscopic retinal pathology in macular telangiectasia type 2.
Drew H.
Scoles 1 , M.
R. Goldberg 2 , C. S. Langlo 3 , Y. N. Sulai 4 , K.
E. Stepien 2 , D. V. Weinberg 2 , J. E. Kim 2 , A.
Dubra 2, 5 , J. Carroll 2, 3 , B. A. Blodi 6 . 1 Biomedical
Engineering, University of Rochester, Rochester,
NY; 2 Ophthalmology, Medical College of
Wisconsin, Milwaukee, WI; 3 Cell Biology,
Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI; 4 The Institute of Optics, University of Rochester, Rochester,
NY; 5 Biophysics, Medical College of Wisconsin,
Milwaukee, WI; 6 Ophthalmology and Visual
Sciences, University of Wisconsin, Madison,
WI *CR
5952 — C0183 Hyperreflective Intraretinal
Spots in Radiation Maculopathy: an in vivo
Spectral Domain OCT Study.
Giulia Midena 1 , R.
Parrozzani 2 , L. Frizziero 3 , S. Vujosevic 3 , E. Pilotto 3 ,
E. Midena 2, 3 .
1 University Campus Bio-Medico,
Roma, Italy; 2 GB Bietti Foundation, IRCCS, Roma,
Italy; 3 Ophthalmology, University of Padova,
Padova, Italy
5953 — C0184 Spectral domain optical coherence tomography imaging of hydroxychloroquine retinal toxicity with and without supplemental enhanced depth imaging testing. Andrew J. Barkmeier, G. Chen.
Ophthalmology, Mayo Clinic, Rochester, MN
5954 — C0185 Autofluorescence and spectraldomain optical coherence tomography may help to characterize Bietti’s crystalline dystrophy in different stages.
Qian LI 1 , X. Peng 2, 1 , Y. Li 2, 1 , X.
Zhu 1 , X. Zhang 2, 1 . 1 Beijing Tongren Eye Center,
Beijing Key Laboratory of Ophthalmology and
Visual Science, Beijing Tongren Hospital, Capital
Medical University, Beijing, China; 2 Beijing
Institute of ophthalmology, Beijing, China
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
388

Exhibit/Poster Hall SA
Thursday, May 08, 2014 10:45 AM-11:45 AM
Thursday – All Posters f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
389

Thursday Papers 12:00 pm – 1:45 pm
5955 – 5968 – Thursday – Papers
S 210DE
Thursday, May 08, 2014 12:00 PM-1:45 PM
Visual Neuroscience
Moderator: Vladimir J. Kefalov
5955 — 12 : 00 Light regulates the outer segment protein transport and disc renewal of mammalian photoreceptors.
Ching-Hwa Sung 2, 1 ,
Y. Hsu 2 2 , J. Chuang .
1 Cell and Developmental
Biology, Weill Med College of Cornell University,
New York, NY; 2 Ophthalmology, Weill Med College of Cornell University, New York, NY
5956 — 12 : 15 Photoreceptor cells with profound structural deficits can support useful vision in mice.
Stewart Thompson 1, 2
P. Singh 1, 2 , X. Liu
S. F. Stasheff
1, 2 , R. Mullins
2, 3 , E. M. Stone 1, 2 .
1
1, 2
, F. R. Blodi 2, 3
, B. A. Tucker
Ophthalmology
& Visual Sciences, University of Iowa, Iowa
1, 2
City, IA;
IA; 3
2 The Stephen A. Wynn Institute for
Vision Research, University of Iowa, Iowa City,
Pediatrics, University of Iowa, Iowa City, IA
,
,
5957
K +
— 12 : 30 The Role of Na + /Ca 2+ ,
exchanger 1 in Mammalian Vision.
Frans
Vinberg
Kefalov 1
1 , T. Wang
Louis, MO;
2 , R. S. Molday 3 , J. Chen 2 , V. J.
.
1 Ophthalmology and Visual Sciences,
Washington University School of Medicine, St
3
2 Cell and Neurobiology, University of Southern California, Los Angeles, CA;
Biochemistry/Molecular Biology, University of
British Columbia, Vancouver, BC, Canada
5958 — 12 : 45 Time course of dark adaptation under conditions of persistent rhodopsin phosphorylation in mouse rods.
Justin
Berr y 1 , R. Frederiksen
C. Cornwall 1
Boston, MA;
. 1
1 , Y. Yao 2 , J. Chen 2 , M.
Department of Physiology and
Biophysics, Boston University School of Medicine,
2 Department of Cell and Neurobiology and Department of Ophthalmology, University of
Southern California, Keck School of Medicine, Los
Angeles, CA
5959 — 1:00 Meta III Limits Opsin Availability
During Pigment Regeneration in Bleached
Mouse Rods.
Rikard Frederiksen 1 , S. Nymark 1, 2 ,
J. Berry 1 , A. V. Kolesnikov
M. C. Cornwall 1
3 , V. J. Kefalov 3 ,
.
1 Department of Physiology and Biophysics, Boston University School of
Medicine, Boston, MA; 2 Department of Electronics and Communications Engineering, University of Technology and BioMediTech, Tampere,
Finland; 3 Department of Ophthalmology and
Visual Sciences, Washington University School of
Medicine, St. Louis, MO
5960 — 1:15 Foveolar cones of monkeys and humans have a unique, still unknown morphology with impact for understanding the Stiles-Crawford effect.
Ulrich
Schraermeyer 1 , S. Schmelzle 2
Julien 1 .
1
, S. Schultheiss 1 , S.
Experimental Vitreoretinal Surgery, Centre for Ophthalmology, Tubingen, Germany;
University Tübingen, Tübingen, Germany
2 of Evolution and Ecology, Eberhard Karls
Institute
5961 — 1:30 Rods may actively drive ganglion cells at surprisingly high light levels in mouse
1 retina.
Alexandra Tikidji-Hamburyan 1 , T. Muench 2 .
Neurosurgery, Stanford University, Stanford, CA;
2 Center for intergrative neuroscience, Tuebingen,
Germany
S 230A-D
Thursday, May 08, 2014 12:00 PM-1:45 PM
Retina
Moderator: Mark S. Humayun
5962 — 12 : 00 Assessing improvements in perception afforded by retinal prostheses in multisensory tasks.
Sara Garcia 1 , K. Petrini 1 ,
L. Da Cruz 2 , G. S. Rubin 1 , M. Nardini 3, 1 .
1 Visual
Neuroscience, UCL Institute of Ophthalmology,
London, United Kingdom; 2 Vitreoretinal Surgery,
Moorfields Eye Hospital, London, United
Kingdom; 3 Psychology, Durham University,
Durham, United Kingdom
5963 — 12 : 15 Spatial resolution of retinal response to photovoltaic stimulation.
Georges
A. Goetz 1, 2
J. Harris 1
, R. Smith 4 , X. Lei
, K. Mathieson 5
1 , T. Kamins 1 ,
Palanker 2, 3 .
1
, A. Sher 4 , D. V.
Electrical Engineering, Stanford
University, Stanford, CA; 2 Hansen Experimental
Physics Laboratory, Stanford University, Stanford,
CA; 3 Ophthalmology, Stanford University,
Stanford, CA; 4 Santa Cruz Institute for Particle
Physics, University of California Santa Cruz, Santa
Cruz, CA; 5 Institute of Photonics, University of
Strathclyde, Glasgow, United Kingdom *CR
5964 — 12 : 30 Photovoltaic Restoration of Sight in Rats with Retinal Degeneration: Assessment of
Spatial Resolution and Visual Functions.
Daniel
V. Palanker
Mandel
Kamins 3
2, 1
1, 2 , H. Lorach 2
, R. Smith 4 , D. Boinagrov
, K. Mathieson 5
, G. A. Goetz
, A. Sher 4 .
1
2
2
3 , Y.
, X. Lei
Hansen
3 , T.
Stanford University, Stanford, CA;
Ophthalmology,
Experimental Physics Laboratory, Stanford
University, Stanford, CA; 3 Electrical Engineering,
Stanford University, Stanford, CA; 4 Institute for
Particle Physics, University of California, Santa
Cruz, CA; 5 Institute of Photonics, University of
Strathclyde, Glasgow, United Kingdom *CR
5965 — 12 : 45 Visual Acuity of Rats with
Photovoltaic Subretinal Prostheses.
Henri
Lorach 1
Lei 3
, Y. Mandel
, T. Kamins
Palanker 1, 2 .
1
1 , G. A. Goetz
3 , L. Galambos 3
1, 3 , P. Huie
, J. Harris 3
1, 2 , X.
, D. V.
Hansen Exp. Physics Lab, Stanford
University, Stanford, CA;
University, Stanford, CA;
2
3
Ophtalmology, Stanford
Electrical Engineering,
Stanford University, Stanford, CA
5966 — 1:00 Receptive field properties in healthy and blind mouse retinas evaluated by stimulation using an implantable subretinal microchip.
Guenther Zeck , F.
Helmhold , M.
Eickenscheidt.
Natural and Medical Sciences
Institute at the University Tübingen , Reutlingen ,
German y
5967 — 1:15 Visual outcome in 26 blind retinitis pigmentosa patients after implantation of subretinal Alpha-IMS devices.
Eberhart Zrenner 1
K. Bartz-Schmidt 1 , C. Chee 2 , F. Gekeler
4 , J. Nemeth 5
1 , T. L.
, H. Sachs
,
Jackson 3
K. Stingl
, R. MacLaren
1 , D. Wong 7 .
1
6 ,
Institute for Ophthalmic
Research, Centre for Ophthalmology, University of Tuebingen, Tuebingen, Germany; 2 Dept.of
Ophthalmology, National University Health System,
Singapore, Singapore; 3 Dept. of Ophthalmology,
School of Medicine, King’s College, London,
United Kingdom; 4 Dept. of Clinical Neurosciences,
Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, United Kingdom;
University, Budapest, Hungary; 6
5
Klinikum Dresden-Friedrichstadt, Dresden,
Germany; 7
Semmelweis
Städtisches
Dept. of Ophthalmology, University of
Hong Kong, Hong Kong, Hong Kong *CR , f
5968 — 1:30 An Update on the Argus II
Epiretinal Implant.
Mark S.
Humayun 1 , L. Da
Cruz 2 , G. Dagnelie 3 , P. E. Stanga 4 , A. C. Ho 5 ,
R. J. Greenberg 6 , D. G. Birch 7 , J. L. Duncan 8 , J.
Sahel 9 . 1 Ophthalmology, Doheny Eye Institute
- USC, Los Angeles, CA; 2 NIHR Biomedical
Research Centre for Ophthalmology, Moorfields
Eye Hospital, London, United Kingdom; 3 Lions
Vision Research and Rehabilitation Center,
Johns Hopkins University, Baltimore, CA;
4 4Manchester Royal Eye Hospital, Manchester,
United Kingdom; 5 Wills Eye Institute, Philadelphia,
PA; 6 Second Sight Medical Products, Inc., Sylmar,
CA; 7 Retina Foundation of the Southwest, Dallas,
TX; 8 University of California, San Francisco, CA;
9 Center Hospitalier National d’Ophtalmologie des
Quinze-Vingts, Paris, France *CR , f
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
390

Thursday – Papers – 5969 – 5983
S 230EF
Thursday, May 08, 2014 12:00 PM-1:45 PM
Visual Psychophysics / Physiological Optics
Moderators: Jens Buehren and
Ramkumar Sabesan
5969 — 12 : 00 Investigating the accommodative response with different sign and magnitudes of spherical aberration.
Aixa Alarcon 1 , F. Baig 1 ,
L. Zheleznyak 2 , G. Yoon 1, 2 .
1 Flaum Eye Institute,
University of Rochester, Rochester, NY; 2 Institute of
Optics, University of Rochester, Rochester, NY
5970 — 12 : 15 Internal code for blur:
Interocular effects.
Aiswaryah Radhakrishnan 1 ,
C. Dorronsoro
Peli 3
1 , L. Sawides
, S. Marcos 1
1 , M. Webster 2 , E.
Laboratory of Visual Optics and
Biophotonics, Instituto de Optica, CSIC, Madrid,
Spain; 2
.
1
Department of Psychology, University of
Nevada, Reno, NV; 3 The Schepens Eye Research
Institute, Boston, MA
5971 — 12 : 30 Clinical Validation of Visual
Simulation for Pseudophakic Patients.
Christina
Schwarz
K. Hileman 3
P. Artal 1
1 , C. Canovas 2
, R. Rosén 2
, S. Manzanera
, P. A. Piers 2
1 , P. Prieto
.
1 Laboratorio de Optica, Universidad de Murcia, Murcia, Spain; 2
Netherlands; 3
AMO, Groningen,
AMO, Santa Ana, CA *CR , f
1 ,
, H. A. Weeber 2 ,
5972 — 12 : 45 Improving binocular through focus visual performance by inducing different interocular orientation of astigmatism.
Joung
Yoon Kim 1 , A. Alarcon 2 , G. Yoon 1, 2 .
1 The Institute of Optics, University of Rochester, Rochester,
NY; 2 Flaum Eye Institute, University of Rochester,
Rochester, NY
5973 — 1:00 Low-cost adaptive lens for vision correction.
Guoqiang Li . 1 Ophthalmology and
Visual Science, Ohio State University, Columbus,
OH; 2 Electrical and Computer Engineering, The
Ohio State University, Columbus, OH
5974 — 1:15 Longitudinal Chromatic
Aberration of the human eye in the visible and near infrared from Hartmann-Shack wavefront sensing, double-pass and psychophysics.
Maria
Vinas, C. Dorronsoro, L. Sawides, D. Cortés, D.
Pascual, A. Radhakrishnan, S. Marcos. Visual
Optics & Biophotonics Lab, Instituto de Optica,
CSIC, Madrid, Spain
S 230GH
Thursday, May 08, 2014 12:00 PM-1:45 PM
Eye Movements / Strabismus / Amblyopia /
Neuro-Ophthalmology
Moderators: Frank A. Proudlock and
Huibert J. Simonsz
5975 — 12 : 00 Disinvestment study of population-wide eye screening in the
Netherlands: effect of omission of preverbal eye screening at age 6-9 months.
Frea Sloot 1 ,
A. Sami 5, 1
Sjoerdsma
Simonsz 1
3
, H. Karaman 5 , S. E. Loudon
, J. Benjamins 4 , H. Raat 2
1 , T.
, H. J.
.
1 Ophthalmology, Erasmus Medical
Center, Rotterdam, Netherlands; 2 Public
Health, Erasmus Medical Center, Rotterdam,
Netherlands; 3 Municipal Health Service,
Amsterdam, Netherlands; 4 Public Health Service
Icare, Meppel, Netherlands; 5 Orthoptics, University of Applied Sciences, Utrecht, Netherlands f
5976 — 12 : 15 Prevalence of amblyopia in school-aged children and variations by ethnicity: a multi-country refractive error study in children.
Ou Xiao
M. He 1 .
1
1 , I. G. Morgan 2 , L. Ellwein
Zhongshan Ophthalmic Center,Sun
Yat-sen university, Guangzhou, China; 2 ARC
Centre of Excellence in Vision Science and
3 ,
Research School of Biology, Australian National
University, Canberra, ACT, Australia; 3 National Eye
Institute,National Institute of Health, Bethesda, MD
5977 — 12 : 30 Simulating Amblyopic
Noise: Reduction in Saccadic Adaptation in
Controls.
Rana Arham Raashid 1 , H. C. Goltz 1, 3 ,
A. Blakeman 2, 3 3 , A. M. Wong .
1 Department of
Neuroscience and Mental Health, Hospital for Sick
Children, Toronto, ON, Canada; 2 Department of
Ophthalmology and Vision Sciences, Hospital for
Sick Children, Toronto, ON, Canada;
Toronto, Toronto, ON, Canada
3 Department of
Ophthalmology and Vision Sciences, University of
5978 — 12 : 45 The Effect of Prenatal
Exposure to Recreational Drugs on Global
Motion Perception at 4.5 Years of Age.
Arijit
Chakraborty 1 , N. Anstice 1
2 .
1
, R. J. Jacobs 1 , B.
Optometry & Vision Thompson 1 , T. Wouldes
Science, The University of Auckland, Auckland,
New Zealand; 2 Psychological Medicine, The
University of Auckland, Auckland, New Zealand
5979 — 1:00 Oculomotor signs during epileptic seizures in children.
Alexandra Hoeh 1 ,
S. Schubert-Bast of Ophthalmology, University of Heidelberg,
Germany
2 , C. Beisse 1
Heidelberg, Germany; 2
. 1 Department
Department of Pediatric
Neurology, University of Heidelberg, Heidelberg,
5980 — 1:15 The developing optic nerve head in infantile idiopathic nystagmus and nystagmus associated to albinism.
Ravi Purohit, H.
Lee, A.
Patel, V.
Sheth, G.
Maconachie , E.
Papageorgiou ,
R.
J.
McLean , I.
Gottlob, F.
A.
Proudlock.
Ophthalmology Group, University of Leicester,
Leicester, United Kingdom
5981 — 1:30 An Exploratory Study of a Novel
Home-Based Binocular Therapy for Childhood
Amblyopia.
Manuela Boss i 1 , E. J. Anderson 1, 2 ,
V. Tailor 3, 6 , P. J. Bex 4 , J. A. Greenwood 5 , A.
Dahlmann-Noor 6 , S. C. Dakin 1, 6 . 1 UCL Institute of
Ophthalmology, London, United Kingdom; 2 UCL
Institute of Cognitive Neuroscience, London,
United Kingdom; 3 Strabismus and Paediatric
Service, Moorfields Eye Hospital, London, United
Kingdom; 4 Massachusetts Eye and Ear Infirmary,
Boston, MA; 5 Cognitive, Perceptual & Brain
Sciences, UCL Psychology & Language Sciences,
London, United Kingdom; 6 National Institute for
Health Research Biomedical Research Centre for
Ophthalmology at Moorfields Eye Hospital NHS
Foundation Trust, London, United Kingdom
S 310A-D
Thursday, May 08, 2014 12:00 PM-1:45 PM
Glaucoma
Moderators: Ernst R. Tamm, Arthur J. Sit and
Makoto Araie
5982 — 12 : 00 The Effect of Cell Stiffness on I- and B-Pore Formation in Schlemm’s
Canal Endothelial Cells.
Darryl R.
Overby 1 , A.
Vahabikashi
Stamer 3
2 , R. Vargas-Pinto 2 , S. T. Braakman
R. Pedrigi 1 , R. Gupta 1
, C. R. Ethier
, K. M. Perkumas
4, 1 , M. Johnson 2 . 1
3 of Bioengineering, Imperial College London,
Evanston, IL; 3 Department of Ophthalmology,
Duke University School of Medicine, Durham,
NC; 4 Department of Biomedical Engineering,
Georgia Institute of Technology, Atlanta, GA
1 ,
, W.
Department
London, United Kingdom; 2 Department of
Biomedical Engineering, Northwestern University,
5983 — 12 : 15 A fluorescent permeability assay for Schlemm’s canal endothelial cells in response to stretch.
Sietse T. Braakman
.
1
1 ,
Bioengineering, W. Stamer 2
Imperial College London, London, United
Kingdom; 2
, D. R. Overby 1
Ophthalmology, Duke University,
Durham, NC *CR f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
391

Thursday Papers 12:00 pm – 1:45 pm
5984 – 6000 – Thursday – Papers
5984 — 12 : 30 A Conditionally Cytotoxic Viral
Vector for Trabecular Meshwork Ablation.
Amardeep Dhaliwal
H. Tseng 2
1 , S. Kola
, J. S. Schuman 1
1 , J. Kim 1 , Z. Zhang 2
, R. N. Weinreb 3
,
A. Loewen 1 . 1
, N.
Department of Ophthalmology,
UPMC Eye Center/University of Pittsburgh
School of Medicine, Pittsburgh, PA; 2 Department of Ophthalmology and Visual Sciences, Yale
University School of Medicine, New Haven,
CT; 3 Hamilton Glaucoma Center, University of
California, San Diego, San Diego, CA
5985 — 12 : 45 Laser Induced Mouse Glaucoma
Model Suitable for Studying Stem Cell-based
Therapy.
Yiqin Du 1, 2 , H. Yun 1 , K. L. Lathrop 1, 3 ,
L. Kagemann 1, 3 , J. S. Schuman 1, 3 .
1 Ophthalmology,
University of Pittsburgh, Pittsburgh,
PA; 2 Developmental Biology, University of
Pittsburgh, Pittsburgh, PA; 3 Bioengineering,
University of Pittsburgh, Pittsburgh, PA
5986 — 1:00 Human Trabecular Meshwork
Exhibit Certain Characteristics of Adiposederived Mesenchymal Stem Cells.
Morgan 1 , J. Wood
Borjesson 1
1 , N. Walker
, C. J. Murphy 1, 2 .
1
1
Paul Russell
, V. Raghunathan 1
School of Veterinary
Medicine, University of California Davis, Davis,
1 , J.
, D.
CA; 2 School of Medicine, University of California,
Davis, Sacramento, CA
5987 — 1:15 In vivo study of the role of SPARC in TGFb2-mediated ocular hypertension.
Swarup
S.
Swaminathan 1 , D. Oh 2 , M. Kang 2 , A. R.
Shepard 3 , I. Pang 4 , D. J. Rhee 2 .
1 Department of Ophthalmology, Massachusetts Eye &
Ear Infirmary, Boston, MA; 2 Department of
Ophthalmology and Visual Sciences, Case Western
Reserve University, Cleveland, OH; 3 Ophthalmology
Research/Glaucoma Research, Novartis
Institutes for Biomedical Research, Fort Worth,
TX; 4 Department of Pharmaceutical Sciences,
University of North Texas Health Sciences Center,
Fort Worth, TX *CR
5988 — 1:30 New Advances on the Gene
Therapy Treatment of Steroid-induced Elevated
IOP in Sheep.
B. Lane
Borras
1
1, 2 .
1
LaKisha Buie
, M. H. Smith 1
1 , R. Elliott 1
, S. D. Lawrence 1
,
, T.
Ophthalmology, University of North
Carolina at Chapel Hill, Chapel Hill, NC; 2 Gene
Therapy Center, University of North Carolina at
Chapel Hill, Chapel Hill, NC
S 310E-H
Thursday, May 08, 2014 12:00 PM-1:45 PM
Retinal Cell Biology
Moderators: Mark E. Kleinman and
Janet R. Sparrow
5989 — 12 : 00 Analysis of the VEGFR-1,-2, and -3 distribution in the adult mouse retina and choroid and the effect of Notch activation on these receptors in laser-induced CNV.
Anne F. Alex
Eter 1 . 1
1 , M. Ehling 2 , R. H. Adams 2 , N.
Department of Ophthalmology, University of Muenster, Medical Center, Muenster,
Germany; 2 Department of Tissue Morphogenesis,
Max-Planck Institute for Molecular Biomedicine,
Muenster, Germany *CR
5990 — 12 : 15 Thy-1 regulates VEGF-induced choroidal endothelial cell migration.
Haibo
Wang , Y.
Jiang, M.
Hartnett . John A Moran Eye
Ctr, Ophthalmology, University of Utah , Salt Lake
City , UT
5991 — 12 : 30 RPE Cytotoxicity and
Caspase Activation after Treatment with
Valproic Acid.
Andre Berner 1 , K. Mohan 1 ,
D. Lou
Sugino
1
2
, J. Brown 1 , J. West
, M. A. Zarbin
Kleinman 1 . 1
University of Kentucky,College of Medicine,
Lexington, KY; 2 Institute of Ophthalmology and
Visual Science, Rutgers New Jersey Medical
School, Newark, NJ
2
1 , R. Kono
, J. Ambati 1
1 , I. K.
, M. E.
Ophthalmology and Visual Sciences,
5992 — 12 : 45 Long-term Intermittent Fasting
(IF) Protects db/db Mice from Development of Diabetic Retinopathy (DR).
Maria Grant 1, 2
Y. Yan
Dominguez
Busik 4
1 , T. Salazar
1
Indianapolis, IN; 2
1 , A. D. Bhatwadekar
, D. Nguyen 1
, M. E. Boulton 1 .
1
, R. Gao 3
University of Florida, Gainesville, FL; 3
1 , J. M.
,
, E. Beli
University Perdue University Indianapolis,
1 , J. V.
Ophthalmology, Indiana
Pharmacology and Therapeutics,
Pediactrics,
Indiana University Perdue University Indianapolis,
Indianapolis, IN; 4 Physiology, Michigan State
University, East Lansing, MI
5993 — 1:00 How RPE cells respond to C5b-9 assembly in vitro.
Apostolos Georgiannakis, K.
Lueck, J.
Greenwood, S.
E.
Moss . Cell Biology,
UCL Institute of Ophthalmology, London , United
Kingdom
5994 — 1:15 Complement Attack by the
Alternative Pathway Increases Gene Expression and Protein Expression of ER Stress Markers in Human RPE Cells.
Yang 2 , G. J. Jaffe 2 .
1
Angel Long
Medicine, Durham, NC;
University Eye Center, Durham, NC
1 , M. Bao 2 , P.
Duke University School of
2 Ophthalmology, Duke
5995 — 1:30 Light and melanopsin regulated eye development.
Copenhagen
OH; 2
3 , R. A. Lang 2 .
1
Sujata Rao
Visual Systems Group, Cincinnati Children,
Cincinnati, OH; 3 Ophthalmology and Physiology,
UCSF, San Francisco, CA
1, 2 , D. R.
Ophthalmic Research,
Cole Eye Institute, Cleveland Clinic, Cleveand,
S 320AB
Thursday, May 08, 2014 12:00 PM-1:45 PM
Physiology/Pharmacology
Moderators: Uday Kompella and Livia S. Carvalho
5996 — 12 : 00 Transport of Topical
Riboflavin across the Cornea with and without Iontophoresis.
Chaiyasan
U. Kompella 2 .
1
Bloomington, IN;
CO; 3
3 , Y. Wang
2
1
Sangly P. Srinivas
, Y. Jiang 1
1 , W.
, W. Tiyaboonchai
Optometry, Indiana University,
3 ,
University of Colorado, Denver,
Naresuan University, Phitsanulok, Thailand
5997 — 12 : 15 Evaluation of prednisoloneacetate (PA) loaded microfilm in a rabbit model of recurrent uveitis.
Xu Wen Ng 1 , M.
Ang 2, 3 , Y. Peng 1
Venkatraman 1 .
1
, C. Wong
Nanyang Technological University,
Singapore, Singapore; 2
2 , T. Wong
Centre, Singapore, Singapore; 3
2, 3 , S.
Singapore National Eye
Singapore Eye
Research Institute, Singapore, Singapore
5998 — 12 : 30 Evaluation of ocular biocompatibility and duration of a bioerodible intravitreal pentablock co-polymer thermosensitive gel and/or nanoparticle ocular drug delivery system.
Brian C. Gilger
Salmon 1 , S. P. Patel
A. K. Mitra 3, 2
3 , P. Velagaleti
, U. Grau 2 .
1
2
1 , J. H.
, S. L. Weiss
Carolina State University, Raleigh, NC; 2
2 ,
Clinical Sciences, North
Inc., Randolph, NJ; 3 i-novion,
School of Pharmacy,
University of Missouri - Kansas City, Kansas City,
MO *CR
5999 — 12 : 45 Oral Delivery of ACE2 or Ang-
(1-7) Bioencapsulated in Plant Cells Protect against Experimental Uveitis and Autoimmune
Uveoretinitis.
Pollob K. Shil 1 , K. Kwon 2 , P. Zhu 1 ,
A. Verma
Q. Li 1 .
1
1 , V. Shenoy
Gainesville, FL; 2
3 , M. Raizada 3 , H. Daniell
Ophthalmology, University of Florida,
2 ,
Biochemistry & Pathology,
University of Pennsylvania, Philadelphia,
PA; 3 Physiology & Functional Genomics,
University of Florida, Gainesville, FL
6000 — 1:00 Prophylactic Treatment of Optimized Retinylamine Loaded PLA
Particles in a Macular Degeneration Mouse
Model.
Golczak
Z. Lu 1 .
1
Anthony Puntel
2 , T. Maeda 3
1 , A. Maeda
, S. Gao 2
3 , M.
, K. Palczewski
Biomedical Engineering, Case Western
Reserve University, Cleveland, OH; 2
2 ,
Pharmacology,
Case Western Reserve University, Cleveland,
OH; 3 Ophthalmology and Visual Sciences, Case
Western Reserve University, Cleveland, OH
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
392

Thursday – Papers – 6001 – 6014
6001 — 1:15 Evaluation of an optimised injection system for retinal gene therapy in human patients.
M Dominik Fischer
M. Groppe 1, 2
Kingdom f
PA *CR
S 320CD
, D. Hickey
R. E. MacLaren 1, 2
United Kingdom;
.
2
1
1 , M. S. Singh
Clinical/Epidemiologic Research
1, 2
1, 2
,
,
Nuffield Laboratory of
Ophthalmology, University of Oxford, Oxford,
Oxford Eye Hospital, Oxford
University Hospitals NHS Trust, Oxford, United
6002 — 1:30 Comparison of dual AAV vector approaches for large gene delivery to the retina.
Livia S.
Carvalho 1 , H. T. Turunen 1 , M. Luna
Velez 2 , J. Bennett 2 , L. H. Vandenberghe 1 . 1 Schepens
Eye Research Institute, Massachusetts Eye and Ear
Infirmary, Harvard Medical School, Boston, MA;
2 Ophthalmology, University of Pennsylvania School of Medicine, F.M. Kirby Center for Molecular
Ophthalmology, Scheie Eye Institute, Philadelphia,
Thursday, May 08, 2014 12:00 PM-1:45 PM
Moderators: Tunde Peto and Kristin J. Meyers
6003 — 12 : 00 Ethnic Variation in the
Distribution and Pattern of Early Age-related
Macular Degeneration Lesions in Whites and
Asians.
Jie Jin Wang 1 , N. D. Joachim 1 , C. Younan 1 ,
, C. Cheng 2, 3 , G. C. Cheung 2, 3 G. Burlutsky
Zheng 4
1
, M. Moffitt 1 , T. Y. Wong 2, 3
, Y.
, P. Mitchell 1 .
1 for Vision Research/Ophthalmol, Westmead
Millennium Institute, University of Sydney
2 Singapore
Ctr
C24, Westmead, NSW, Australia;
Eye Research Institute, Singapore National Eye
Centre, Singapore, Singapore; 3 Department of Ophthalmology, Yong Loo Lin School of
Medicine, National University of Singapore and
National University Health System, Singapore,
Singapore; 4 Saw Swee Hock School of Public
Health, National University of Singapore and
National University Health System, Singapore,
Singapore *CR
6004 — 12 : 15 Impact of Fellow Eye on
Incidence, Progression and Regression of Age-
Related Macular Degeneration: Results from
Multi-state Models Applied to the Beaver Dam
Eye Study.
Ronald Gangnon 1
Klein 4
. 1
, K. E. Lee 4
, T. A. Sivakumaran 3
, B. E.
, R.
Biostatistics and Medical Informatics, Klein 4
, S. K. Iyengar 2
University of Wisconsin School of Medicine and
Public Health, Madison, WI; 2
University, Cleveland, OH; 3
Case Western Reserve
Cincinnati Children’s
4
Hospital Medical Center, Cincinnati, OH;
Ophthalmology and Visual Sciences, University of
Wisconsin School of Medicine and Public Health,
Madison, WI
6005 — 12 : 30 Frequency of subretinal drusenoid deposits (SDD) in Older Eyes in
Normal Macular Health or with Early or
Intermediate Age-related Macular Degeneration
(AMD).
David Neely, M.
E.
Clark, C.
E.
Huisingh ,
G.
McGwin , R.
M.
Feist, Y.
Zhang, C.
Owsley , C.
A.
Curcio . UAB Department of Ophthalmology,
Birmingham , AL
6006 — 12 : 45 Better Eye Health for Aging
Baby-boomers: Generational Differences in the
5-yr Incidence of AMD.
Karen J. Cruickshanks 1, 2 ,
D. S. Dalton 1 , R. Klein 1 , B. E. Klein 1 , D.
Nondahl 1 .
1 Ophthal & Vis Sci, U of WI SMPH,
Madison, WI; 2 Population Health Sciences, U of WI
SMPH, Madison, WI
6007 — 1:00 Prevalence and incidence of blindness and other degrees of visual impairment in patients with neovascular age-related macular degeneration in a well-defined region of the United Kingdom.
Miranda Buckle , R.
Healy, R.
Johnston . Ophthalmology Department ,
Gloucestershire Eye Unit , Gloucestershire
NHS Foundation Trust, Cheltenham , United
Kingdom *CR
6008 — 1:15 Higher Serum Leptin Levels
Are Protective of Age-related Macular
Degeneration.
Charumathi Sabanayagam 1, 3 , J.
Liao 2 , C. Cheng 1, 2 , G. C. Cheung 2 , P. Mitchell 4 ,
J. Wang 4 , S. Sethi 5 , T. Y. Wong 1, 2 .
1 Singapore
Eye Research Institute, Singapore,
Singapore; 2 Ophthalmology, National University of Singapore, Singapore, Singapore; 3 Duke-
NUS Graduate Medical School, Singapore,
Singapore; 4 Centre for Vision Research, Sydney,
NSW, Australia; 5 Department of Pathology, National
University of Singapore, Singapore, Singapore
6009 — 1:30 Correlates of Metabolic Syndrome
Are Associated with Low Macular Pigment
Despite Moderate to High Intakes of Macular
Carotenoids.
Wallace
S. K. Iyengar
A. Mares 1 . 1
6
Kristin J.
3 , L. Tinker 4
Meyers 1 , Z. Liu
, C. Engelman 5
1 , R.
, B. A. Blodi
, E. Johnson 7 , M. Snodderly 8 , J.
Ophthal & Visual Sciences, Univ
1, 2 of Wisconsin, Madison, Madison, WI; 2 Fundus
Photograph Reading Center, University of
Wisconsin Madison, Madison, WI; 3 Department of Epidemiology, University of Iowa College of
,
Public Health, Iowa City, IA; 4 Dept. of Cancer
Prevention Research Prog, Fred Hutchinson Cancer
Research Center, Seattle, WA; 5 Dept of Population
Health Sciences, University of Wisconsin Madison,
Madison, WI; 6 Epidemiology, Case Western
University, Clevland, OH; 7 Jean Mayer USDA
Human Nutrition Research Center on Aging, Tufts
University, Boston, MA; 8 Department of Human
Ecology, The University of Texas, Austin, TX *CR
S 320GH
Thursday, May 08, 2014 12:00 PM-1:45 PM
Biochemistry/Molecular Biology
Moderators: Dusanka Deretic and Alecia K. Gross
6010 — 12 : 00 Monitoring Kinetic Changes of
Proper and Improper Rhodopsin Transport ex vivo.
Alecia K.
Gros s 1, 2 , V. Parpura 2 , J. D.
Sammons 3 . 1 Vision Sciences, Univ of Alabama at
Birmingham, Birmingham, AL; 2 Neurobiology,
University of Alabama at Birmingham,
Birmingham, AL; 3 Cellular, Developmental and
Integrative Biology, University of Alabama at
Birmingham, Birmingham, AL
6011 — 12 : 15 Differential Roles of Splice
Variants of Very Low-density Lipoprotein
Receptor in Regulating the Wnt Signaling
Pathway.
K. Oka 4
Qian Chen
, J. Ma 1, 3 .
1
1, 2 , Y. Takahashi 2, 3 , K. Lee 3
Department of Physiology,
University of Oklahoma Health Sciences center,
,
Oklahoma City, OK; 2 Department of Endocrinology,
University of Oklahoma Health Sciences center,
Oklahoma City, OK; 3 Harold Hamm Diabetes
Center, University of Oklahoma Health Sciences center, Oklahoma City, OK;
Medicine, Houston, TX
4 Department of
Molecular & Cellular Biology, Baylor College of
6012 — 12 : 30 Studies of Protein Interaction of the Chaperonin CCT in Photoreceptors.
Maxim
Sokolo v 1 , M. Belcastro 1 , X. Gao 1 , V. Y. Arshavsky 2 ,
N. P. Skiba 2 , S. Sinha 1 .
1 Ophthalmology, West
Virginia Univ Eye Institute, Morgantown,
WV; 2 Albert Eye Research Institute, Duke
University, Durham, NC
6013 — 12 : 45 Differential Expression of
IRBP, Albumin, BIGH3 and PNA Binding in the Interphotoreceptor Matrix Versus Choroid in Diabetes, AMD and Glaucoma.
Andrew
T. Tsin 1 , T. Zou 2
Fernandez
Fernandez
2
, R. LeBaron
, P. Hires
2, 4
3
Biology, University of Texas San
Antonio, San Antonio, TX; 2
1 , V. Gonzalez-
, J. Lonsdale 3 , F. Gonzalez-
.
1
Med Res Svc/Veterans
Affairs, SUNY at Buffalo, Ross and SUNY Eye
Institutes, Buffalo, NY;
Interchange, Philadelphia, PA;
NY
3 National Disease Research
4 Pahtology and
Anatomical Sciences, SUNY at Buffalo, Buffalo,
6014 — 1:00 Rhodopsin is directly involved in the activation of Arf4 mediated by the Arf GEF
GBF1 during ciliary targeting.
Dusanka Deretic,
J.
Wang . Surgery, Univ of New Mexico Sch of Med,
Albuquerque, NM f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
393

Thursday Papers 12:00 pm – 1:45 pm
6015 – 6028 – Thursday – Papers
6015 — 1:15 Use of small molecules to correct mutant bestrophin-1 localization.
Carolina
Uggenti 1, 2 , L. Swanton 2 , F. D. Manson 1, 3 .
1 Faculty of Medical and Human Sciences, Manchester
Centre for Genomic Medicine, Institute of
Human Development, Manchester, United
Kingdom; 2 Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom; 3 St.
Mary’s Hospital, Central Manchester University
Hospitals NHS Foundation Trust, Manchester
Academic Health Science Centre, Manchester,
United Kingdom
6016 — 1:30 Phosphorylation of the Usher syndrome 1G protein SANS controls Magi2mediated endocytosis.
Uwe Wolfrum 1 , B.
Knapp 1 , P. Jores 1 , R. Roepman 2, 3 , H. Kremer 2, 3 ,
E. vanWijk 2, 3 , K. Bauss 1 . 1 Cell & Matrix Biology,
Inst. of Zool., Johannes Gutenberg Univ of Mainz,
Mainz, Germany; 2 Dept. Human Gen., Radboud
Univ. Nijmegen Medical Centre, Nijmegen,
Netherlands; 3 Nijmegen Centre Mol. Life Sci.,
Radboud Univ. Nijmegen Medical Centre,
Nijmegen, Netherlands
S 330CD
Thursday, May 08, 2014 12:00 PM-1:45 PM
Anatomy/Pathology
Moderators: Hans E. Grossniklaus and
Matthew W. Wilson
6017 — 12 : 00 (Neonatal) Retinoblastoma in the First Month of Life: Comparison of the
Pre- and Post-Intraarterial Chemotherapy
Era.
Talia R.
Kaden 1 , J. H. Francis 1 , B. Marr 1 , S.
E. Brodie 3 , Y. Gobin 2 , D. H. Abramson 1 . 1 Memorial
Sloan Kettering Cancer Center, New York,
NY; 2 NewYork-Presbyterian Hospital/Weill Cornell
Medical Center, New York, NY;
Medical Center, New York, NY
3 The Mount Sinai
6018 — 12 : 15 Intravitreal chemotherapy virtually eradicates indication to external beam irradiation for vitreous seeding in retinoblastoma.
Francis L. Munier
Gaillard
Popovic
1 , A. Balmer
2 .
1
1 , S. Houghton
1 , M.
1 , M. Beck
Ophthalmolgy, Jules-Gonin Eye
Hospital, Lausanne, Switzerland; 2 Unité d’hématooncologie pédiatrique, Centre Hospitalier
Universitaire Vaudois, Lausanne, Switzerland
6019 — 12 : 30 A Prospective Single Institution
Trial Using Toptecan Based Chemotherapy for the Treatment of Bilateral Intraocular
Retinoblastoma: 5 Year Results.
Matthew W.
Wilson 1, 2 , R. Brennan 1, 3
C. Rodriguez-Galindo 5 .
1
, S. Mao 4 , I. Qaddoumi 3
Ophthal/Hamilton Eye
,
Int, Univ of Tennessee Health Sci Ctr, Memphis,
TN; 2 Surgery, St Jude Children’s Research Hospital,
Memphis, TN; 3 Oncology, St Jude Children’s
Reseach Hospital, Memphis, TN; 4 Biostatics,
St Jude Children’s Reseach Hospital, Memphis,
TN; 5 Pediatric Oncology, Dana Farber Cancer
Institute, Boston, MA f
6020 — 12 : 45 An Update on the
Development of sd-rxRNA for Retinoblastoma
Therapy.
Michael Byrn e 1 , D. Qi 2 , K. Stachelek 2 ,
H. Singh 2 , J. Cardia 1 , L. Panderarinathan 1 ,
K. Holton 1 , K. Bulock 1 , D. Cobrinik 2 , P. A.
Pavco 1 . 1 Pharmacology, RXi Pharmaceuticals,
Westborough, MA; 2 Children’s Hospital Los
Angeles, Los Angeles, CA *CR
6021 — 1:00 The 2014 American
Brachytherapy Society (ABS) Guidelines for
Plaque Brachytherapy of Uveal Melanoma and Retinoblastoma.
Paul T.
Finger . Ophthalmic
Oncology , New York Eye Cancer Center ,
New York , NY
6022 — 1:15 Comparison of Uveal Melanoma
Cytopathologic Sample Retrieval in Transscleral
Versus Vitrectomy-Assisted Transvitreal Fine
Needle Aspiration Biopsy.
Melinda Chang, B.
J.
Glasgow, T.
A.
McCannel . Ophthalmology, Jules
Stein Eye Institute, Los Angeles, CA
6023 — 1:30 Primary Oculo-Cerebral lymphoma (POCL): Efficacy of intravenous high-dose methotrexate (MTX) based polychemotherapy without radiotherapy on intraocular disease control.
Diem Trang Nguyen 1 ,
N. Cassoux
Cossec 5
2 , S. Choquet 3
, A. Omuro 6
K. Hoang Xuan 6
, C. Soussain
, P. Lehoang
, V. Touitou 1 .
1
1
4 , C. Le
, B. Bodaghi 1 ,
Ophthalmology,
DHU View Maintain, Pitié Salpêtriere Hospital,
Paris, France; 2 Ophthalmologic oncology, Insitut
Curie, Paris, France; 3 Clinical Hematology, Pitie
Salpetriere hospital, Paris, France; 4 Oncology,
Institut René Huguenin, Saint Cloud,
France; 5 Biostatistics, medical informatic, Pitie
Salpetriere Hospital, Paris, France;
France *CR , f
6 Neuro-
Oncology, Pitie Salpetriere Hospital, Paris,
S 330EF
Thursday, May 08, 2014 12:00 PM-1:45 PM
Lens
Moderators: Juliet A. Moncaster and
Frank J. Lovicu
6024 — 12 : 00 Non-Invasive Detection of
Age-Related and Alzheimer’s Disease Linked
Pathology in the Lenses of Human Subjects with Down Syndrome.
Srikant Sarangi 1 , O.
Minaeva
Weng 3
1, 2
Goldstein 2, 1
, J. A. Moncaster 2
, D. M. Ledoux 3
.
1
, C. Rook 3
, D. G. Hunter 3
, F.
, L. E.
Biomedical Engineering, Boston
University, Boston, MA; 2 Boston School of
Medicine, Boston University, Boston, MA;
3 Ophthalmology, Boston Children, Boston, MA *CR
6025 — 12 : 15 Oxygen Metabolism in Primary
Human Lens Epithelial Cells; Association with
Age, Diabetes and Glaucoma.
C. J. Siegfried
C. Beebe
MO; 2
1, 3 .
1
1 , Y. Shui 1 , F. Bai 1 of Medicine, Tokyo, Japan; 3
Miyuki Kubota
, A. J. Huang 1 , D.
Ophthalmology, Keio University School
Cell Biology and
Physiology, Washington University School of
Medicine, St. Louis, MO
1, 2
Ophthalmology & Visual Sciences,
Washington Univ School of Medicine, St Louis,
,
6026 — 12 : 30 Comparison of Two Photopolymerizable Gel Oxygen Barrier Formulations for Prevention of Oxidative Damage to the
Crystalline Lens.
Martin G. O’Toole 1 , B. M.
Nunn 1
Gobin 4
, Q. Zeng 2 , M. Humphrey
, T. H. Tezel 2, 3
2
1 , S. Schaal 2 , A. S.
.
1 Bioengineering, University of Louisville, Louisville, KY; Ophthalmology and Visual Sciences, University of Louisville,
Louisville, KY; 3 Anatomy and Neurobiology,
University of Louisville, Louisville, KY;
Heart Institute, Houston, TX
4 Texas
6027 — 12 : 45 Confirmation of association of axial length and young age with post-operative steroid-induced intraocular pressure rise in a large cataract cohort.
Mukhtar Bizrah 1, 2
A. Mahroo
Thompson 4
1, 3 , O. Kailani 4 , T. Dar 5
, C. J. Hammond 1, 3 .
1
, A. Nag 3 , J.
Ophthalmology,
King’s College London, St Thomas’
, O.
Hospital Campus, London, London, United
Kingdom;
Hospitals NHS Foundation Trust, London, United
Kingdom; 3
2 Ophthalmology, The Hillingdon
Department of Twin Research and
Genetic Epidemiology, King’s College London, St
West Thomas’ Hospital, London, United Kingdom; 4
Kent Eye Centre, Princess Royal University
Hospital, London, United Kingdom; 5 King’s
College London, London, United Kingdom
6028 — 1:00 Enhancement of Ubiquitination
Promotes the Degradation of Mutant Crystallins in Lens.
Fu Shang 1, 2 , Z. Liu 1, 2 , M. Wu 1, 2 , X.
Zhang 1, 2 , Y. Liu 1 , A. Taylor 2 .
1 The State Key
Laboratory of Ophthalmology, Zhongshan
Ophthalmic Center, Guangzhou, China;
Tufts University, Boston, MA
2 HNRCA,
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
394

Thursday – Papers– 6029 – 6042
6029 — 1:15 response pathway activation involved in three kinds of cataract.
Zhongshan Ophthalmic Center, Guangzhou, China
S 330GH
Different Unfolded protein
Jing Yang , S.
Zhou , J.
Gu.
Thursday, May 08, 2014 12:00 PM-1:45 PM
Immunology/Microbiology
Moderators: Manabu Mochizuki and
Russell W. Read
6030 — 12 : 00 A genome wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.
Jonas
Kuiper 1, 5 ,
T. Mutis 5
, J. Setten 2 , P. I. de Bakker
, B. Koeleman 2 .
1
2, 4 , A. Rothova 3
Ophthalmology,
University medical center utrecht,
Utrecht, Netherlands; 2 Medical Genetics,
University Medical Center Utrecht, Utrecht,
Netherlands; 3 Ophthalmology, Erasmus University
Medical Center, Rotterdam, Netherlands; of Harvard and MIT, Cambridge, MA;
4 Program in Medical and Population Genetics, Broad Institute
5 Clinical
Chemistry and Hematology, University Medical
Center Utrecht, Utrecht, Netherlands
6031 — 12 : 15 Incidence and Risk Factors for Ocular Hypertension in Adults with Noninfectious Uveitis.
Ebenezer Daniel 1, 2 , M.
Pistilli 2 , H. Sen 4 , E. B. Suhler 12, 5
C. Foster 9, 10 , D. A. Jabs 11, 7
T. Rosenbaum 12, 6
, J. E. Thorne
, R. B. Nussenblatt
, J. H. Kempen 1, 3 . 1
4
8, 7
University of Pennsylvania, Philadelphia,
PA; 2 Center for Preventive Ophthalmology and
,
, J.
The Scheie
Eye Institute, The Perelman School of Medicine,
Biostatistics, Department of Ophthalmology,
University of Pennsylvania, Philadelphia, PA;
3 Center for Clinical Epidemiology and Biostatistics,
Department of Biostatistics and Epidemiology,
University of Pennsylvania, Philadelphia, PA; 4 The
Laboratory of Immunology, National Eye Institute,
Bethesda, MD; 5 Portland Veteran’s Affairs Medical
Center, Portland, OR; 6
Portland, OR; 7
The Devers Eye Institute,
The Department of Epidemiology,
The Johns Hopkins University Bloomberg
School of Public Health, Baltimore, MD; 8 The
Department of Ophthalmology, The Johns Hopkins
University School of Medicine, Baltimore,
MD; 9 The Massachusetts Eye Research and Surgery
Institution, Cambridge, MA; 10 Department of
Ophthalmology, Harvard Medical School, Boston,
MA; 11 The Department of Ophthalmology, The
Icahn School of Medicine at Mount Sinai, New
York, NY; 12 Department of Ophthalmology, Oregon
Health and Science University, Portland, OR *CR
6032 — 12 : 30 Risk of Ocular Complications in
Non-infectious Uveitis.
Martha Skup 1 , N. Tundia 1 ,
R. Sorg 2
Dick 3 . 1
, C. Zhao 2 , J. Chao 1
Group, Inc, New York, NY; 3
, P. Mulani 1 , A. D.
AbbVie Inc., North Chicago, IL; 2 Analysis
Bristol Eye Hospital,
Bristol, United Kingdom *CR
6033 — 12 : 45 Risk factors for reduced visual acuity in non-infectious intermediate, posterior, and panuveitis.
Douglas A.
Jabs 1
M. L. Van Natta 2
S. Lightman 4
J. H. Kempen 5 . 1
, M. M. Altaweel
, J. E. Thorne 2
3
, J. T. Holbrook
2 of Medicine at Mount Sinai, New York, NY;
,
, J. P. Dunn
2 ,
Ophthalmology, Icahn School
2 ,
Biostatistics & Epidemiology, Johns Hopkins
Bloomberg School of Public Health, Baltimore,
MD; 3 Ophthalmology & Visual Science,
University of Wisconsin-Madison, Madison, WI;
4 Ophthalmology, Moorfields Eye Hospital, London,
United Kingdom; 5 Ophthalmology, Biostatistics, &
Epidemiology, Scheie Eye Institute, University of
Penn, Philadelphia, PA f
6034 — 1:00 Etiologic diagnosis of anterior uveítis in mexican population.
Lorena Ramirez,
M.
Pedroza-Seres, V.
M.
Bautista . Conde de
Valenciana , Mexico , Mexico
6035 — 1:15 Uveitic Macular Edema Outcomes by Subtype: Results of a Randomized Controlled
Trial.
Elizabeth Shen
R. Thundikandy
Weinrib 1
2
, T. Porco 1, 5
1 , S. R. Rathinam
, A. Kanakath 3
, N. Acharya 1, 4 .
1
2 , M. Babu
, E. Browne 1 , R.
Francis I.
Proctor Foundation, University of California, San
3
Francisco, San Francisco, CA; 2 Aravind Eye Care
System, Madurai, India, Madurai, India; 3 Aravind
Eye Care System, Coimbatore, India, Coimbatore,
India; 4 Department of Ophthalmology, University of California, San Francisco, San Francisco, CA;
5 Department of Epidemiology & Biostatistics,
University of California, San Francisco, San
Francisco, CA f
,
6036 — 1:30 Visual acuity outcome of non-infectious intermediate, posterior, and panuveitis in the Multicenter Uveitis Steroid
Treatment (MUST) Trial.
John H.
Kempen 1 ,
M. L. Van Natta 2 , M. M. Altaweel 3 , J. P. Dunn 4 ,
D. A. Jabs 5, 2 , S. Lightman 6 , J. E. Thorne 2, 4 , J. T.
Holbrook 2 . 1 Ophthal-Biostatistics & Epidemiol,
Scheie Eye Inst/Univ of Penn, Philadelphia,
PA; 2 Epidemiology, Center for Clinical Trials,
Johns Hopkins University Bloomberg School of
Public Heatlh, Baltimore, MD; 3 Ophthalmology,
Fundus Photograph Reading Center, University of
Wisconsin, Madison, WI; 4 Ophthalmology, Wilmer
Eye Institute, Johns Hopkins University School of
Medicine, Baltimore, MD; 5 Ophthalmology and
Medicine, Icahn School of Medicine at Mount
Sinai, New York, NY; 6 Institute of Ophthalmology,
University College London, London, United
Kingdom f
S 331A-D
Thursday, May 08, 2014 12:00 PM-1:45 PM
Cornea
Moderators: Satoshi Kawasaki, Friedrich E. Kruse and Winston W. Kao
6037 — 12 : 00 The microRNA-103/107 family regulates the cell cycle to confer quiescence on stem cell-enriched limbal keratinocytes.
Jong
Kook Park 1 , H. Peng 1 , J. V. Katsnelson
W. Yang 1 , R. Lavker 1
2
University, Chicago, IL; 2
Chicago, IL
, S. Yang
Rush Medical School,
1 ,
.
1 Dermatology, Northwestern
2
6038 — 12 : 15 DNA methylation profiling of limbal- and fibroblast-derived iPSC suggests retention of some epigenetic signatures of parental cells.
D. Sareen 1
V. Punj 2
Ljubimov 1, 3 .
1
Tanya M. Spektor
, L. A. Ornelas 1
, Y. S. Rabinowitz 1
1 , M. Saghizadeh 1
, V. Funari 1 , J. Tang
, C. Svendsen 1 , A.
Regenerative Medicine Institute,
Cedars-Sinai Medical Center, Los Angeles, CA;
Epigenome Center, University of Southern
California, Los Angeles, CA; 3 6David Geffen
School of Medicine, UCLA, Los Angeles, CA
1 ,
,
6039 — 12 : 30 MicroRNA-184 and microRNA-
450b are essential regulators of corneal epithelial fate and ocular development.
Ruby Shalom-
Feuerstein 1
Aberdam 2
1 , L. Serror 1 , D. Putin
, D. Aberdam 2 of Technology, Haifa, Israel;
Paris, France
2
, E. Nir 1 , E.
.
1 Technion - Israel Institute
University of Paris,
6040 — 12 : 45 Efficient induction of neural crest cells from human pluripotent stem cells.
Fukuta 2
Kinoshita 1 .
1
Hiroshi Tanaka
, M. Ueno 1
1 , Y. Nakai 1
, M. Ikeya 2
, M.
, J. Toguchida 2 , S.
Ophthalmology, Kyoto Prefectural
University of Medicine, Kyoto, Japan; 2 Center for iPS Cell Research and Application, Kyoto
University, Kyoto, Japan *CR
6041 — 1:00 Induction Of Human
Adipose Derived Stem Cells Into Limbal
Epithelial Cells For The Reconstruction
Of Corneal Epithelium.
Xiao-Wei Tan 1 , M.
Setiawan
S. Mehta
1 , G. Goh
1, 2
1 , C. Nyein 1 , D. T. Tan 2, 3
2 Singapore National Eye
Center, Singapore, Singapore; 3
School, Duke-NUS, Singapore, Singapore
, J.
.
1 Singapore Eye Research Institute,
Singapore, Singapore;
Graduate Medical
6042 — 1:15 Effect of Wnt signaling small molecule modulators on the cultured human
LSCs.
Justyna Kanska , M.
N.
Nakatsu, J.
Zheng, S.
X.
Deng . Ophthalmology, UCLA , Los Angeles, CA f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
395

6043 – Thursday – Papers
6043 — 1:30 Prevention of Corneal
Scarring by Human Corneal Stromal Stem
Cells.
Andrew Hertsenberg 1 , S. Basu 2 , J. L.
Funderburgh 1 .
1 Ophthalmology, University of
2
Pittsburgh School of Medicine, Pittsburgh, PA;
Cornea and Anterior Segment Services, L V Prasad
Eye Institute, Hyderabad, India
Thursday Papers 12:00 pm – 1:45 pm
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
396

Thursday – Posters – 6044 – 6067
Exhibit/Poster Hall SA A0121-A0155
Thursday, May 08, 2014 12:00 PM-1:45 PM
Cornea
Moderator: Kathryn Dumbleton
6044 — A0121 Exploring Silicone Hydrogel
Material Properties to Deliver Various Ocular
Therapeutics.
Frances Lasowski , G.
Conant , H.
Sheardown.
Chemical Engineering, McMaster
University , Hamilton , ON , Canada
6045 — A0122 Disinfection efficacy of hexamidine against ocular pathogens.
Bandarage
Mahesh K.
Bandara
M. D. Willcox
Holden 1, 2 . 1
2
1 , R. S. Bandara
, P. Lazon De La Jara
1
1
, H. Zhu 1, 2
, B. A.
,
Brien Holden Vision Institute, Sydney,
NSW, Australia;
NSW, Australia
2 School of Optometry and Vision
Science, University of New South Wales, Sydney,
6046 — A0123 Biocidal Efficacy of Hydrogen
Peroxide Solutions Against Clinical Isolates of
Fungal Pathogens.
Brien C.
David, D.
McGrath, D.
Callahan , J.
Mason, J.
Bair , T.
Hilfiker , P.
A.
Walsh.
RD Microbiology , Bausch & Lomb , Rochester,
NY *CR
6047 — A0124 Correlations of In vitro Assays for Assessing Cytotoxicity and Biocompatibility of Contact Lens Multipurpose Solutions.
Ling
Huang, M.
Salvador Silva.
R&D - Biological
Sciences , Abbott Medical Optics , Santa Ana,
CA *CR
6048 — A0125 Antimicrobial Efficacy of Multipurpose Disinfecting Solutions against Clinical Isolates Following Multiple
Rechallenge.
Marina Milenkovic , J.
Cook . Corneal
R&D, Abbott Medical Optics , Santa Ana, CA *CR
6049 — A0126 Antibacterials Properties and
Ophthalmic Applications of Xylitol.
Charles Q.
Yu , D.
Choi . Eye Institute at Stanford , Stanford
University , Palo Alto , CA
6050 — A0127 Development of Soft Contact
Lens for Drug Delivery Using Zwitter Ionic
Hydrogel.
Toru Matsunaga 1, 2 , T. Tashiro 1 ,
T. Sato 2
Japan; 2
1 , T. Funaki
Department of Ophthalmology, Juntendo
University Graduate School of Medicine, Tokyo,
Japan *CR
2 , A. Murakami .
1 Reserch and Development, Seed Co Ltd, Saitama,
6051 — A0128 Assessment of the growth of Stenotrophomonas maltophilia,
Elizabethkingia meningoseptica and Delftia acidovorans in contact lens cases and on recovery media.
David J.
McCanna, L.
Liu, J.
Seo,
L.
N.
Subbaraman , L.
W.
Jones.
Centre for Contact
Lens Research , School of Optometry and Vision
Science, University of Waterloo , Waterloo , ON ,
Canada
6052 — A0129 Simultaneous Determination of the Rate of Disinfection and Peroxide
Neutralization of a Novel Hydrogen Peroxide
Disinfecting System.
Deborah McGrath, K.
A.
Millard, D.
Cordero, T.
W.
Morris . Microbiology,
Bausch&Lomb, Rochester, NY *CR
6053 — A0130 Delivery of the secretagogue
Ap4A from conventional and silicone hydrogel soft contact lenses: effect on tear secretion.
Jesus
Pintor 1 , C. Dominguez-Godinez 2 , A. Martin-Gil 1 ,
G. Carracedo 2 , J. Gonzalez-Meijome 3 , A. Guzman-
Aranguez 1 . 1 Bioquimica y Biologia Molecular
IV, F. de Optica UCM, Madrid, Spain; 2 Optica
II, F. Optica, UCM, Madrid, Spain; 3 Clinical &
Experimental Optometry Research Lab, Center of
Physics, University of Minho, Braga, Portugal
6054 — A0131 Patient-Reported Wearing
Experience from Daily Disposable Wearers
Over Age 40 from the TEMPO Registry.
Sheila
B.
Hickson-Curran 1 , R. L. Chalmers
W. Gleason 4 . 1
Vision Care, Inc., Jacksonville, FL; 2
2 , L. J. Keay 3 ,
Medical Affairs, Johnson & Johnson
Consultant, Atlanta, GA; 3
Clinical Trial
The George Institute,
Sydney, NSW, Australia; 4 Foresight Regulatory
Strategies, Boston, MA *CR , f
6055 — A0132 Patient age is not a significant barrier to adoption of customized scleral devices.
Eda Dou, D.
L.
Kornberg , Y.
Wang , R.
M.
St Clair, M.
Lee, M.
I.
Rosenblatt , P.
Sood , A.
G.
Alzaga Fernandez, J.
B.
Ciralsky , K.
C.
Sippel .
Ophthalmology, Weill Cornell Medical College,
New York , NY
6056 — A0133 OCT based meniscometry for evaluating tear film behavior on contact lenses.
Dorota H. Szczesna-Iskander
S. Adamus 1
1 , M. Bartuzel
Wroclaw University of Technology, Wroclaw,
Poland; 2
1 , D. Iskander 2 .
Institute of Physics,
Institute of Biomedical Engineering and Instrumentation, Wroclaw University of
Technology, Wroclaw, Poland
1 ,
6057 — A0134 Understanding Contact Lens
Mechanics.
Kara Maki , D.
Ross . School of
Mathematical Sciences , Rochester Institute of
Technology , Rochester, NY *CR
6058 — A0135 Comparing and optimizing cholesterol extraction from hydrogel and silicone hydrogel contact lens materials.
Miriam Heynen ,
D.
Trieu, H.
I.
Lorentz, L.
W.
Jones.
Centre for
Contact Lens Research School of Optometry &
Vision Science, University of Waterloo , Waterloo ,
ON , Canada
6059 — A0136 Localization of full-length recombinant human proteoglycan 4 in commercial contact lenses using confocal microscopy.
Steven Cheung 1 , L. N. Subbaraman 1 ,
T. A. Schmidt 2 , L. W. Jones 1 . 1 CCLR, School of
Optometry and Vision Science, University of
Waterloo, Waterloo, ON, Canada; 2 Faculty of
Kinesiology, University of Calgary, Calgary, AB,
Canada *CR
6060 — A0137 DeltaVision Spectris Imaging of
Lipid Deposits on Contact Lens Surfaces.
Shyam
Panthi , S.
D.
Hanlon , A.
R.
Burns, J.
J.
Nichols.
The Ocular Surface Institut e ,University of Houston,
College of Optometry, Houston, TX *CR
6061 — A0138 The effect of lactoferrin on lysozyme deposition and activity on silicone hydrogel contact lenses.
Brad Hall 1 , L. W. Jones 1, 2 ,
J. Forrest 2, 1 . 1 CCLR School of Optometry and
Vision Science, University of Waterloo, Waterloo,
ON, Canada; 2 Physics & Astronomy, University of
Waterloo, Waterloo, ON, Canada *CR
6062 — A0139 Investigation of diurnal blink patterns using a continuous blink tracking device in soft contact lens wearers.
Colleen Heckley
J. D. Rodriguez
Ousler 2 .
1
1 , E. Angjeli
Andover, MA *CR
1 , K. J. Lane 1 , G. W.
R & D, Ora, Inc, Andover, MA;
1 ,
2 Ora, Inc,
6063 — A0140 Comparative Surface
Smoothness Durability of a Novel Silicone
Hydrogel Material.
Mohinder M.
Merchea, K.
A.
Wygladacz, D.
Hook . Bausch + Lomb , Rochester,
NY *CR
6064 — A0141 Effect of trehalose on protection of desiccation-induced human corneal epithelial cell damage and lubrication of contact lens surfaces.
Qian Garrett
Ariyavidana 1
De La Jara 1, 2
, I. Perera 1
.
1
1, 2 , N. Khandekar
, K. Ehrmann
South Wales, Sydney, NSW, Australia
1, 2
1 , A.
, P. Lazon
Biological Sciences, Brien Holden
Vision Institute, Sydney, NSW, Australia; 2 School of
Optometry and Vision Science, University of New
6065 — A0142 Impact of Current and
Previous Contact Lens Wear on Meibomian
Glands and Tear Film Characteristics.
Waleed
Alghamdi 1, 2 , M. Markoulli 2 , B. A. Holden 1, 2 , E.
B. Papas 1, 2 .
1 Vision Cooperative Research Centre,
Brien Holden Vision Institute, Sydney, NSW,
Australia; 2 School of Optometry & Vision Science,
University of New South Wales, Sydney, NSW,
Australia
6066 — A0143 Confocal analysis of the ocular tear film - contact lens interface.
Scott Schatz 1, 2 ,
H. Laubach 2 .
1
Grundy, VA; 2
Appalachian College of Optometry,
College of Medical Sciences, Nova
Southeastern University, Fort Lauderdale, FL *CR
6067 — A0144 Atomic Force Microscopy and
Coefficient of Friction Analysis of Unworn and
Worn Soft Contact Lenses.
Jeffery Schafe r 1 ,
R. Steffen 1 , K. A. Wygladacz 1 , C. Lusignan 1 , D.
Hook 1 , K. Simoncelli 2 . 1 Bausch & Lomb, Rochester,
NY; 2 SUNY College of Optometry, New York,
NY *CR f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
397

Thursday Posters 12:00 pm – 1:45 pm
6068 – 6084 – Thursday – Posters
6068 — A0145 The large-scale epidemiological study of the change in the number of prescriptions of various contact lenses in
Japan - The results of analysis of 8 years of prospective research of approximately 930,000 eyes of Japanese subjects -.
Masao Yoshida 1
Mizuki 2 , T. Kawagoe
E. Okada 5 .
1
2 , J. Nakamura 3
University School of Medicine, Mitaka-shi,
Japan; 2 Department of Ophthalmology, Yokohama
City University School of Medicine, Yokohama,
Japan; 3
MD; 4
National Eye Institute of NIH, Bethesda,
National Human Genome Research Institute of NIH, Bethesda, MD; 5
Yokohama, Japan
Okada Eye Clinic,
, N.
, M. Takeuchi
Department of Public Health, Kyorin
4 ,
6069 — A0146 The large scale epidemiological study of the change in the number of prescription for single vision and the multifocal contact lenses - The results of comparative analysis of 8 years prospective research of approximately 180,000 eyes of Japanese subjects aged 40 years or older -.
Eiichi Okada 1 , N.
Mizuki 2 , T. Kawagoe 2 , J. Nakamura 3 , M. Takeuchi 4 ,
M. Yoshida 5 .
1 Okada Eye Clinic, Yokohama,
Japan; 2 Department of Ophthalmology, Yokohama
City University School of Medicine, Yokohama,
Japan; 3 National Eye Institute of NIH, Bethesda,
MD; 4 National Human Genome Research Institute of NIH, Bethesda, MD; 5 Department of Public
Health, Kyorin University School of Medicine,
Mitaka, Japan
6070 — A0147 Contact lens discomfort associated with bulbar conjunctival microvascular alternations.
Jianhua Wang
1, 2
1
, D. DeBuc
, H.
1 .
1
Jiang 1 , Z. Xu
Ophthalmology, Bascom Palmer Eye Inst Lib,
Miami, FL; 2
, A. Tao 1, 2 , C. Liu 1
Ophthalmology and Optometry,
Wenzhou Medical College, Wenzhou, China *CR
6071 — A0148 Solute-Uptake Characterization of Water-Gradient Laminated Soft Contact
Lenses.
David E.
Li u 1 , T. J. Dursch 1 , Y. Oh 1 ,
C. J. Radke 1, 2 . 1 Department of Chemical and
Biomolecular Engineering, University of California,
Berkeley, Berkeley, CA; 2 Vision Science Group,
University of California, Berkeley, Berkeley, CA
6072 — A0149 Power profiles measured on
NIMO TR1504 (Lambda-X): repeatability and effects of lens decentration for single vision, bifocal and multifocal contact lenses.
Eon Kim 1
R. C. Bakaraju
Ehrmann 1, 3 .
1
1 , I. Perera 1 , B. A. Holden
Technology, Brien Holden Vision
Institute, Sydney, NSW, Australia; 2
1, 2 , K.
,
Sydney, NSW, Australia;
Vision Science, University of New South Wales,
Sydney, NSW, Australia
3
Vision CRC,
School of Optometry and
6073 — A0150 Specular Microscopy to demonstrate morphological changes of corneal endothelial cells (EC) with Corneal Oxigen
Deficiency (COD) in Contact Lens (CL)
Wears.
Andre Heck , F.
C.
Abib . Anatomy, Federal
University of Parana , Curitiba , Brazil *CR
6074 — A0151 Ocular Comfort with Contact
Lenses Compared with Spectacles and No
Vision Correction.
E. B. Papas
Holden
France
P. Situ 1
1, 2 . 1
1, 2
NSW, Australia;
Percy Lazon De
, J. Diec
, C. G. Begley 1
1 , P. Xu
La
. 1
Jara
Optometry and Vision Science, UNSW, Sydney,
NSW, Australia *CR , f
Performance.
Dawn Meye r 1
, T. L. Simpson 2
University, Bloomington, IN;
1
2
, N. Peng
Waterloo, Waterloo, ON, Canada
School of Medicine , Kayseri, Turkey
1
,
Indiana
University of
1, 3 ,
, B. A.
Brien Holden Vision Institute, Sydney,
2 Vision Cooperative Research
Centre, Sydney, NSW, Australia; 3 School of
6075 — A0152 Risk factors for contact lensrelated microbial keratitis: a case-control multicenter study.
Tristan Bourcier , S.
Arnaud .
Hôpitaux Universitaires de Strasbourg , Strasbourg ,
6076 — A0153 Within- and Between-Observer
Repeatability of Real-Time and Video-
Recorded Slit Lamp Measures of Contact Lens
, P. S. Kollbaum
6077 — A0154 Piggy-Back Contact Lens
Systems After Corneal Trauma.
Caroline
Cromelin , S.
R.
Lambert, B.
M.
Russell.
Ophthalmology, Emory University , Atlanta, GA
6078 — A0155 A new alternative fitting approach for providing an adequate comfort and visual performance in keratoconus:
Soft HydroCone (Toris K) silicone hydrogel keratoconus lenses.
Koray Gumus, N.
Parmaksiz.
Department of Ophthalmology, Erciyes University
Exhibit/Poster Hall SA A0206-A0235
1
Thursday, May 08, 2014 12:00 PM-1:45 PM
Clinical/Epidemiologic Research
Moderators: Susan Vitale and Ruth E. Hogg
6079 — A0206 Prevalence And Causes
Of Vision Impairment And Blindness In
Older Adults In An Urban Census Sector Of
Parintins, Brazilian Amazon Region.
Joao M.
Furtad o 1, 2 , S. Munoz 3
Cohen 4, 5 , J. M. Cohen
Cavascan 1
, A. Berezovsky
4, 5 , P. H. Morales
, S. E. Watanabe
R. Salomao 1 . 1
1
1 , M. J.
1 , N. Nunes
, R. Belfort, Jr.
1 , S.
Departamento de Oftalmologia e
Ciências Visuais, Escola Paulista de Medicina,
Universidade Federal de São Paulo, Sao
Paulo, Brazil; 2 Departamento de Oftalmologia,
Otorrinolaringologia e Cirurgia de Cabeça e
Pescoço, Faculdade de Medicina de Ribeirão Preto,
USP, Ribeirão Preto, Brazil;
Salud Publica, Universidad de La Frontera, Temuco,
Chile;
Brazil; 5
3 Departamento de
4 Instituto de Olhos de Manaus, Manaus,
Departamento de Cirurgia, Setor de
Oftalmologia, Faculdade de Medicina, Universidade
Federal do Amazonas - UFAM, Manaus, Brazil
6080 — A0207 Prevalence and Causes of
Visual Impairment and Blindness in an Urban
Population: The South Brazilian Bocaiuva
Study.
Lisandro Sakata , V.
M.
Sakata , A.
L.
Rocha,
G.
Sakuno , A.
Mozena , P.
Watanabi , T.
Nakayama ,
M.
Sato , A.
R.
Moreira, K.
Sakata . Universidade
Federal do Parana , Curitiba , Brazil *CR
6081 — A0208 Prevalence of visual impairment in elderly Europeans: geographical and temporal trends.
Cecile DelCourt . Universite Bordeaux
Segalen, INSERM , Bordeaux , France *CR
6082 — A0209 Vision Impairment among
Older Adults Residing in Federally Subsidized
Senior Housing Communities.
Amanda Elliott 1
G. McGwin 2, 3 , C. Owsley 2 .
1 Nursing, University of South Florida, Tampa, FL; 2
,
Ophthalmology,
University of Alabama at Birmingham,
Birmingham, AL; 3 Epidemiology, University of
Alabama at Birmingham, Birmingham, AL
6083 — A0210 Vision Impairment and
Blindness due to Age-Related and other Macular
Degenerations Globally: A Systematic Review and Meta-Analysis.
Jill Keeffe 1 , J. B. Jonas 2 , R.
Bourne 3 , T. Y. Wong 8 , J. L. Leasher 5 , K. S. Naidoo 6 ,
H. Price 7 , S. R. Flaxman 4 , S. Resnikoff 9 , H. R.
Taylor 10 . 1 L V Prasad Eye Institute, Hyderabad,
India; 2 Ophthalmology, University of Heidelberg,
Mannheim, Germany; 3 Vision and Eye Research
Unit, Anglia Ruskin University, Cambrodge,
United Kingdom; 4 School of Computer Science and Heinz College, Carnegie Mellon University,
Pittsburgh, PA; 5 Nova Southeastern University, Fort
Lauderdale, FL; 6 African Vision Research Institute,
University of Kwazulu Natal, Durban, South
Africa; 7 Vision and Eye Research Institute, Anglia
8
Ruskin University, Cambridge, United Kingdom;
Singapore Eye Research Institute, Singapore,
Singapore; 9 Brien Holden Vision Institute, Sydney,
NSW, Australia; 10 Melbourne School of Population and International Health, University of Melbourne,
Melbourne, VIC, Australia
6084 — A0211 Prevalence of Visual
Impairment and Blindness in Chinese
American Adults: The Chinese-American
Eye Study.
Torres
Varma 1 .
1
Chunyi Hsu 1 , J. S. Kim
1 , R. McKean-Cowdin
2
2 , S. Wu
2 , S. P. Azen
1
University of Southern California,
Los Angeles, CA
2
, M.
, R.
University of Illinois at Chicago, Los
Angeles, CA;
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
398

6085 — A0212 Prevalence and causes of vision loss in Sub-Saharan Africa: 1990-2010.
Kovin
S.
Naidoo
Flaxman
1, 2
5 , J. B. Jonas
K. Pesudovs
, S. Gichuhi
9 , H. Price
3 , M. Basáñez
6 , J. Keeffe 7
10 , J. L. Smith
4 , S. R.
, J. L. Leasher 8 ,
Programs, Brien Holden Vision Institute, Durban,
South AfriCA; 2
Institute, Durban, South Africa; 3
11 . 1 Global
Research, African Vision Research
Infectious
Ophthalmology,
University of Nairobi, Nairobi, Kenya; 4 disease epidemiology, School of Public
Health, London, United Kingdom; 5 School of
Computer Science & Heinz College, Pittsburg,
PA; 6 Ophthalmology, Universitätsmedizin,
Mannheim, Manheim, Germany; 7 Ophthalmology,
University of Melbourne, Melbourne, VIC,
Australia; 8 Optometry, Nova Southeastern
University, Fort Laudedale, FL; 9 NHMRC
Centre for Clinical Eye Research, Adelaide, SA,
Australia; 10 Vision & Eye Research Unit, Anglia
University, Cambridge, United Kingdom;
Uganda
11 London
School of Hygiene & Tropical Medicine, London,
6086 — A0213 Is optic neuritis incidence rising? Evidences from an epidemiological study in Barcelona, Spain 2008-2012.
Elena
H. Martinez-Lapiscina 1 , E. Fraga-Pumar 1 , X.
Pastor 2 , M. Gómez 3 , A. Conesa 2 , R. Lozano-
Rubí 2 , B. Sanchez-Dalmau 1, 4 , A. Alonso 5 , P.
Villoslada 1 .
1 Neurology, IDIBAPS-Hospital Clinic of Barcelona, Barcelona, Spain; 2 Department of Medical Informatics, Hospital Clinic of
Barcelona-University of Barcelona, Barcelona,
Spain; 3 Direction of Strategy and Planning,
Hospital Clinic of Barcelona and Technical Office
- AISBE, Barcelona, Spain; 4 Ophthalmology,
IDIBAPS- Hospital Clinic of Barcelona, Barcelona,
Spain; 5 Division of Epidemiology and Community
Health, School of Public Health, University of
Minnesota, Minneapolis, MN *CR
6087 — A0214 Prevalence Of Near Vision
Impairment In Middle-Aged And Older
Adults In An Urban Census Sector Of
Parintins, Brazilian Amazon Region.
Solange
R.
Saloma
Mitsuhiro 1 o 1 , S. Munoz
Y. Sacai 1 , M. J. Cohen 4
2 , J. M. Furtado 1, 3
, J. M. Cohen 5, 4
, S. B. Arruda
Berezovsky 1 . 1
4
, P.
, M. R.
, R. Belfort, Jr.
1 , A.
Departamento de Oftalmologia,
Universidade Federal de Sao Paulo, Sao Paulo,
Brazil; 2 Salud Publica, Universidad de La Frontera,
Temuco, Chile; 3 Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeca e Pescoco, Faculdade de
Medicina de Ribeirao Preto, USP, Ribeirao Preto,
Brazil; 4
Brazil; 5
Instituto de Olhos de Manaus, Manaus,
Cirurgia, Divisao de Oftalmologia,
Faculdade de Medicina - Universidade Federal do
Amazonas, Manaus, Brazil
Thursday – Posters – 6085 – 6101
6088 — A0215 Emergence of intravitreal injections in a National Health System: 2002-
2012.
ANA P.
. 1
MARQUE
A. Rocha-Sousa
R. Santana 1
3
S 1 , A. F. Macedo 2
, J. Perelman 4
, A.
, A. M. Baptista
Policy Management and Health
2 ,
Administration, National School of Public Health;
Nova University, Lisboa, Portugal; 2 Centre/
Department of Physics and Optometry, Minho
University, Braga, Portugal; 3 Department of Senses
Organs, Faculty of Medicine; University of Porto,
Porto, Portugal;
Portugal
4 Health Economics, National
School of Public Health; Nova University, Lisboa,
6089 — A0216 Incremental Cost-Utility Ratio of Intravitreal Aflibercept Compared with
Ranibizumab for the Treatment of Macular
Edema Secondary to Central Retinal Vein
Occlusion.
Alan F. Cruess 4 , M. Jeddi 1 , R. Goeree 2 ,
G. Blackhouse 2 , M. Eriksson 3 .
1 Bayer, Toronto, ON,
Canada; 2 Faculty of Health Sciences, McMaster
University, Hamilton, ON, Canada; 3 Bayer AB,
Solna, Sweden; 4 Ophthalmology, Dalhousie
University, Halifax, NS, Canada *CR
6090 — A0217 Loaner ophthalmoscopes in conjunction with simulation and clinical training improve fundoscopy skills of third year medical students.
Jennifer Park 1
Levine 1 , L. A. Eisen 3
A. C. Raff 4
Rosenberg 2
, U. Mian 2
, M. Meholli
Bronx, NY;
.
2
1
5
, R. M.
, M. Calvo
, W. B. Burton 6
4 ,
, J. B.
Albert Einstein College of Medicine,
Ophthalmology and Visual Sciences,
Albert Einstein College of Medicine and Montefiore
Medical Center, Bronx, NY; 3 Critical Care
Medicine, Albert Einstein College of Medicine and
Montefiore Medical Center, Bronx, NY; 4 Medicine,
Albert Einstein College of Medicine and Montefiore
Medical Center, Bronx, NY; 5 Medicine, Albert
Einstein College of Medicine and Jacobi Medical
Center, Bronx, NY; 6 Family and Social Medicine,
Albert Einstein College of Medicine, Bronx, NY
6091 — A0218 A Glimpse into the Resident’s
Perspective: Current attitudes and future outlook.
Saba Al-Hashimi, R. Song, M. Desai.
Boston Medical Center, Boston, MA
6092 — A0219 Measurable Indicators of
Eye Care Integration into Health Systems in the Western Pacific.
.
1
Helen Chan 1, 2 ,
Western Pacific Regional A. Mueller 1
Office, World Health Organisation, Manila,
Philippines; 2 Ophthalmology, Royal Melbourne
Hospital, Melbourne, VIC, Australia
6093 — A0220 Vision, Older Drivers & Public
Safety: Can An Annual Eye Examination
Requirement Reduce Motor Vehicle Collision
In a Cost Effective Way?.
Lori L.
Grover 1 , C.
Shih 2 . 1 Health Solutions, Arizona State Univ,
CONHI Ctr Translational Health Science, Phoenix,
AZ; 2 School of Public Health & Health Services,
George Washington University, Washington, DC
6094 — A0221 Improving Eye Care Follow-
Up Adherence in Patients with Diabetes:
The Effectiveness of Patient Contracts in a
Community-Based Eye Screening.
Chelsea L.
Aleo 1 , A. P. Murchison
E. Mayro 1 , B. Leiby 2
1 , L. A. Hark
, L. Pizzi 2
1 , Y. Dai
, J. A. Haller 1
1
.
1 Research, Wills Eye Hospital, Philadelphia,
,
PA; 2 Thomas Jefferson University, Philadelphia,
PA *CR , f
6095 — A0222 The Effectiveness of a Tailored
Intervention to Increase Follow-Up Adherence in Patients with Glaucoma.
Judie Tran , M.
Waisbourd, D.
Weiss, A.
P.
Murchison, L.
Katz ,
G.
L.
Spaeth , J.
A.
Haller , L.
A.
Hark . Department of Research , Wills Eye Hospital , Philadelphia ,
PA *CR, f
6096 — A0223 A Comparison of Three
System-Based Interventions to Improve
Follow-Up Adherence in a Primary Eye Care
Setting.
Brianna Kenney , L.
A.
Hark , A.
P.
Murchison, R.
Bailey , J.
A.
Haller , J.
A.
Bilson .
Wills Eye Hospital , Philadelphia , PA *CR, f
6097 — A0224 Medicare Payment and
Cataract Surgical Volume.
Dan Gong , J.
Lin, J.
C.
Tsai . Department of Ophthalmology & Visual
Science, Yale School of Medicine , New Haven, CT
6098 — A0225 A cost effectiveness analysis of cataract surgery.
Lucidi 1
Domenico Lepore
, M. Ruggeri 2 , G. Damiani 3 .
1
1 , F.
Deparment of Ophthalmology, Catholic University of the
Sacred Heart, Rome, Italy; 2 Department of Health
Economics, Catholic University of the Sacred
Heart, Rome, Italy;
Heart, Rome, Italy
3 Department of Hygiene and
Public Health, Catholic University of the Sacred
6099 — A0226 Patient-Reported Outcomes in
Optometric Glaucoma Care.
Paul P.
Le e 1, 2 , S.
Asrani 2 , W. Rafferty 2 , D. Lobach 3 , C. E. Huisingh 4 ,
G. McGwin 4 . 1 Ophthalmology and Visual
Sciences, University of Michigan, Ann Arbor,
MI; 2 Ophthalmology, Duke University, Durham,
NC; 3 Family Medicine, Duke University, Durham,
NC; 4 Ophthalmology, University of Alabama,
Birmngham, AL f
6100 — A0227 Telemedicine versus inperson examination: High patient satisfaction with a teleglaucoma model for detection and management of glaucoma suspects in rural
Alberta.
Sourabh Arora, K.
Kurji, I.
Kherani, C.
J.
Rudnisky , K.
F.
Damji.
Ophthalmology, University of Alberta, Edmonton , AB , Canada *CR
6101 — A0228 Comparing the subjective and the objective severity of affections observed at emergency room in ophthalmology.
Aurelie
Pison 1 , P. Rothschild 1, 2 , C. Mehanna 1 , A. P. Brezin 1 ,
J. Bourges 1, 2 .
1 Ophthalmology, Pole Hotel-Dieu
Cochin, site Hotel-Dieu, Sorbonne Paris Cité university, Paris Descartes School of medicine,
Assistance Publique-Hopitaux de Paris, Paris,
France; 2 Team 17, INSERM UMRS 872, CIC des
Cordeliers, Paris, France f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
399

Thursday Posters 12:00 pm – 1:45 pm
6102 – 6123 – Thursday – Posters
6102 — A0229 Impact of the Lions Lens on a school vision clinic and on child’s perception of academic performance.
Sandra S.
Block, M.
A.
Suckow . School Based Vision Clinic , Illinois
College of Optometry, Chicago, IL
6103 — A0230 Glaucoma Screening in African
American Communities: A Comparative
Effectiveness Analysis.
Reena Vaswani, L.
A.
Al -
Aswad, G.
A.
Cioffi , D.
M.
Blumberg . Columbia
University , New York , NY
6104 — A0231 Final versus referral diagnosis of visual impairment in a tertiary low vision rehabilitation centre for children.
Evelyn
Longhin 1 , M. Vinciati 2
E. Convento 3
E. Midena 1, 3
Rome, Italy;
, I. A. Fregona 3
.
1
2
, I. Cermakova 2 , G. Zabeo 3 ,
, R. Parrozzani 1 ,
Fondazione G. B. Bietti IRCCS,
Italy; 3
Robert Hollman Foundation, Padova,
Department of Ophthalmology, University of
Padova, Padova, Italy
6105 — A0232 Incidence and frequency of positive findings in inpatient ophthalmology consultations at Boston Medical Center.
Neil
Vyas , J.
Gittinger.
Ophthalmology, Boston
University / Boston Medical Center , Boston , MA
6106 — A0233 New referrals to an Australian ophthalmic outpatient clinic.
Fiona Stapleton 1 ,
S. C. Lim 1 , M. Knipe 2 , N. Verma 2 .
1 School of
Optometry and Vision Science, University of
New South Wales, Kensington Sydney, NSW,
Australia; 2 Eye Clinic, Royal Hobart Hospital,
Hobart, TAS, Australia
6107 — A0234 Variability in Access to
Hospital Eye Care in Southern China.
Yingfeng
Zheng, D.
Wang , M.
He . State Key Laboratory of
Ophthalmology, Zhongshan Ophthalmic Center ,
Sun Yat-sen University , Guangzhou, China
6108 — A0235 Demand, capacity and flow of care in ophthalmology in the Campinas region, Brazil.
Denise F.
Oliveira , C.
E.
Arieta .
OPhthalmology, UNICAMP, Campinas , Brazil
Exhibit/Poster Hall SA A0247-A0255
Thursday, May 08, 2014 12:00 PM-1:45 PM
Visual Psychophysics / Physiological Optics /
Retina
Moderator: David G. Birch
6109 — A0247 Visual training with microperimetry for patients with unstable/ excentric fixation after macular surgery.
Patricia
Udaondo, A.
Hervas Ontiveros, S.
García Delpech,
D.
Salom, R.
Martínez Costa, . Cisneros-Lanuza.
Ophthalmology, La Fe University Hospital,
Valencia, Spain *CR
6110 — A0248 Comparison of Kinetic Visual
Fields (Goldmann and Octopus) and Threshold
Visual Fields (Octopus macular static and
Full-Field Stimulus Threshold) in Patients with Inherited Retinal Diseases.
Ronald A.
Schuchard
Koenekoop
. 1
1, 5 , D. G. Birch
4
2
, A. K. Bittner 3
, G. Dagnelie
, L. M. Wood
3
4
, R. K.
, C. S.
Stanford University, Palo Alto, CA; Barnes 5
2 Retina Foundation of the Southwest, Dallas, TX;
3 Johns Hopkins Wilmer Eye Institute, Baltimore,
MD; 4 McGill University Health Centre, Montreal,
QC, Canada;
CA *CR
5 VA Palo Alto HCS, Palo Alto,
6111 — A0249 Progression in Patients with
Advanced Retinal Degenerative diseases
(RDD) followed with Full-field Stimulus
Threshold (FST) Testing.
Martin Klein 1 , D. G.
Birch 1, 2 . 1 Retinal Degenerations Laboratory, Retina
Foundation, Dallas, TX; 2 Ophthalmology, UT
Southwestern Medical Center, Dallas, TX
6112 — A0250 Spatial Summation Across the Visual Field: Implications for Visual Field
Testing.
Sieu Khuu 1 , M. Kalloniatis 1, 2 .
1 School of
Optometry and Vision Science, The University of
New South Wales, Sydney, NSW, Australia; 2 The
School of Optometry and Vision Science and the
Centre for Eye Health, University of New South
Wales, Sydney, NSW, Australia *CR
6113 — A0251 Registration accuracy of
NIDEK MP-1 micro-perimeter in ‘follow-up’ testing.
Arunkumar Krishnan , N.
B.
Patel, S.
B.
Stevenson, H.
E.
Bedell . Optometry, Univ of
Houston College of Optometry, Houston, TX
6114 — A0252 Real-Time Retinal Imaging with Integrated Visual Function Testing Using the Digital Light Ophthalmoscope.
Matthew
S.
Muller 1
Kollbaum 2
, A. E. Elsner 1, 2
, B. L. Petrig
Bloomington, IN; 2
1 .
, K. Baskaran 2 , E. J.
1 Aeon Imaging, LLC,
School of Optometry, Indiana
University, Bloomington, IN *CR
6115 — A0253 Comparison of the Peripheral retinal sensitivity between professional soccer players and non-athletes.
vinicius
B. pereira 1 , V. Pereira 2 , R. A. Pereira 3 , N.
Kasahara 1 . 1 Ophtalmology, Santa Casa de
São Paulo, São Paulo, Brazil; 2 Medical,
University Anhembi Morumbi, São Paulo,
Brazil; 3 Ophtalmology, Instituto Panamericano da
Visão, Goiânia, Brazil
6116 — A0254 The Relation Between
Functional Visual Acuity and Functional
Visual Field for Elderly Drivers with Normal
Cognitive Status.
Tsutomu Shimizu, S.
Masui, M.
Saiki, H.
Torii, M.
Dogru, K.
Tsubota, K.
Negishi.
Ophthalmology, Keio University , Tokyo, Japan *CR
6117 — A0255 Retinal sensitivity by means of microperimetry in patients with different drusen type.
Giovanni Staurenghi , A.
Giani, M.
V.
Cigada .
Department of Biomedical and Clinical Sci ( Luigi
Sacco) , University of Milan, Milano , Italy *CR
Exhibit/Poster Hall SA A0297-A0350
Thursday, May 08, 2014 12:00 PM-1:45 PM
Glaucoma
Moderator: Gus Gazzard
6118 — A0297 Effect of Clear Lens Extraction in Primary Angle Closure.
Tanuj Dada , A.
Rathi,
R.
Sharma , T.
Agarwal, M.
Vanathi, S.
Khokhar,
R.
B.
Vajpayee . Dr Rp Center For Ophthalmic
Sciences , All India Institute Of Medical Sciences ,
New Delhi, India
6119 — A0298 Effect of Intraoperative factors on IOP lowering after phacoemulsification surgery.
Sona Chaudhry 1 . 1 University
MD; 2
, O. J. Saeedi 2 of Maryland - Baltimore, Baltimore,
Ophthalmology, University of Maryland -
Baltimore, Baltimore, MD *CR
6120 — A0299 Induced astigmatism in patients undergoing combined surgery of phacoemulsification, intraocular lens implantation and trabeculectomy.
Carolina Prado,
M. Zavala Aznar, S. Silva Romano, R. Castaneda
Diez. Asociación Para Evitar La Ceguera en México
I.A.P., Mexico City, Mexico
6121 — A0300 Post Operative Refractive
Outcomes in Patients Undergoing Combined
Cataract Extraction, Endocyclophotocoagulation and iStent Placement (ICE Procedure).
Kristin O.
Chapman, C. E. Starr, K. Bohm, N. M. Radcliffe.
Ophthalmology, Weill Cornell Medical College,
New York, NY *CR
6122 — A0301 Comparing the Effect of Laser
Peripheral Iridotomy to Lens Extraction on
Anterior Segment Morphology in Narrow Angle
Eyes using Anterior Segment Optical Coherence
Tomography (ASOCT).
Jacob Gross 1, 2 , L. Baker 3 ,
A. Chuang 2 , L. S. Blieden 2, 3 , N. P. Bell 2, 3 , R. M.
Feldman 2, 3 .
1 The University of Texas School of
Public Health, Houston, TX; 2 Ruiz Department of
Ophthalmology and Visual Science, The University of Texas Medical School at Houston, Houston, TX;
3 Robert Cizik Eye Clinic, Houston, TX *CR
6123 — A0302 Laser peripheral iridotomy versus trabeculectomy as an initial treatment for primary angle-closure glaucoma: a nonrandomized comparative study.
Yuanbo Liang
Liang 1, 2 , Y. Chen 2 , S. Fan 3
R. Thomas 7 , S. Rong 6
, H. Meng
, N. Wang 2 .
1
4 , X. Wang 5 ,
Glaucoma,
School of Optometry and Eye Hospital, Wenzhou,
Wenzhou, China; 2 Ophthalmology, Beijing Tongren
Hospital, Beijing, China;
Hospital, Handan, China;
3
4
Glaucoma, Handan Eye
Glaucoma, Anyang
Eye Hospital, Anyang, China;
Eye Hospital, Fushun, China; 6
5
Glaucoma, Queensland Eye Institute, Queensland,
QLD, Australia f
Glaucoma, Fushun
OVS, The Chinese
7
University of Hong Kong, Hong Kong, China;
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
400

6124 — A0303 Intraocular pressure (IOP) related pattern in patients with primary angle closure (PAC) and primary angle closure glaucoma (PACG) before and after laser peripheral iridotomy (LPI).
Shibal
Bhartiya 1 , S. Dhawan
R. Goedkoop 2
1 , S. Simon-Zoula 2 ,
Glaucoma Facility, Fortis
Memorial Research Institute, Gurgaon, Haryana,
India; 2
.
1
Clinical Development and Medical Affairs,
Sensimed AG, Lausanne, Switzerland *CR , f
6125 — A0304 All-Cause Mortality Following
Combined Cataract Extraction and Minimally
Invasive Glaucoma Surgery Compared to
Cataract Extraction Alone and Traditional
Glaucoma Surgery.
Paul Baciu, A.
R.
Sheraly, D.
Crandall , N.
R.
Imami.
Ophthalmology, Henry Ford
Hospital , Detroit, MI
6126 — A0305 Comparison of Outcomes of iStent with Cataract Surgery versus Cataract
Surgery Alone in Open-Angle Glaucoma.
Mia
Miller 1, 2
A. Goyal
, B. Hughes
1
1 , J. Apple 1
, A. Shukairy
Institute, Detroit, MI; 2
1
, C. Kim
, C. Kim 1 .
1
School of Medicine, Detroit, MI *CR
1 , J. Tannir
Kresge Eye
Wayne State University
1 ,
6127 — A0306 Comparison Between
Endhotelial Cell Loss After Express Implant
And Mics, Phaco Mics Safe-Trabeculectomy
And Phaco With Hydrus Implant.
Romeo
1
Altafini 1 , A. M. Fea 3 , S. Morselli 2 , F. M. Grignolo 3 .
Ophthalmology Unit, San Bortolo Hospital,
Vicenza, Vicenza, Italy; 2 Ophthalmology Unit, San
Bassiano Hospital, Bassano del Grappa, Vicenza,
Italy; 3 Ophtalmology Unit, Department of Clinical
Pathophysiology, University of Turin, Turin, Italy
6128 — A0307 Phacoemulsification combined with cyclodyalisis in patients with cataract and open angle glaucoma.
Alfredo Piñeyro-Garza,
S.
Lopez-Rubio, M.
A.
de Alba . Ophthalmology,
Tecnologico de Monterrey, Monterrey, Mexico
6129 — A0308 Risk Factors for Early
Postoperative Intraocular Pressure Elevation after Phacoemulsification in Trabeculectomized
Eyes.
Wonmo Gu, S. Cha, S. Lim, J. Chu, M.
Sagong. Department of Ophthalmology, Yeungnam
University College of Medicine, Daegu, Republic of Korea
6130 — A0309 Clinical and Structural
Markers of One-Year Angle Surgery
Outcomes.
D. M. Reed
S. E. Moroi 1
1
Samir Shah
, A. Argento
.
1
1 , S. Bansal 1 , J. Gilbert
2 , N. Chakraborty
Ophthalmology and Visual
2 ,
Sciences, University of Michigan, Ann Arbor,
MI; 2 Mechanical Engineering, University of
Michigan - Dearborn, Dearborn, MI *CR
1 ,
6131 — A0310 Postoperative IOP is not related to intrascleral lake morphology after Non Penetrating Deep Sclerectomy without scleral implant.
Cristian Dalmasso 1 ,
J. J. Urcola 1, 2 , E. Vecino 2 , J. Cabrerizo 1 , G.
Saracibar 2 .
1 Ophthalmology, Hospital Universitario
Araba, Vitoria Gasteiz, Spain; 2 Universidad del País
Vasco, Vitoria Gasteiz, Spain
Thursday – Posters – 6124 – 6148
6132 — A0311 A Retrospective Analysis of
Outcomes of Resident-Performed Glaucoma
Surgery at a Veterans Affairs Medical
Center.
Robert A. Sharpe 1 , E. Sharpe 2 .
1
2
Medical
University of South Carolina, Charleston, SC;
Ophthalmology, Ralph H Johnson VAMC,
Charleston, SC
6133 — A0312 Clinical Experience with Ahmed
M4 Tube-Shunt in Various Types of Glaucoma:
A Pilot Study.
Timothy Sullivan , V.
Cvintal, W.
D.
Hu , F.
Ekici, N.
Sabherwal, M.
Waisbourd, M.
J.
Pro, M.
R.
Moster . Glaucoma , Wills Eye Hospital ,
Philadelphia , PA *CR
6134 — A0313 Ahmed Glaucoma Valve (AGV
) vs. Gold Micro Shunt (GMS ) in Refractory
Glaucoma. 5 year results of a Prospective,
Randomize Study.
Modi Goldenfeld . Goldschleger
Eye Institute, The Sam Rothberg Glaucoma center ,
Ramat Gan, Israel *CR, f
6135 — A0314 Sequential Glaucoma Drainage
Devices in Pediatric Glaucoma.
Niloufar
Abdollahi, A.
Chen , A.
L.
Coleman, J.
A.
Giaconi,
S.
K.
Law, F.
Yu , J.
Caprioli . Jules Stein Eye
Institute, Los Angeles, CA *CR
6136 — A0315 Outcomes of Sequential
Glaucoma Drainage Implants in Refractory
Glaucoma.
Naryan Sabherwal 1, 2
W. D. Hu 2 , F. Ekici 2
M. J. Pro .
1
Philadelphia, PA;
PA *CR
2
, M. R. Moster
, M. Waisbourd 2
2
Drexel University College of Medicine,
2
, V. Cvintal 2 ,
,
Wills Eye Hospital, Philadelphia,
6137 — A0316 Postoperative outcome in eyes with glaucoma treated with the Boston type I keratoprosthesis.
Pablo Romero , P.
P.
Chen , T.
T.
Shen , M.
A.
Slabaugh . Ophthalmology, University of Washington , Seattle, WA
6138 — A0317 Suprachoroidal Drainage
Devices - Six Months Experience.
Andre Vicente,
B.
Borges , R.
Anjos, A.
Cabugueira , L.
vieira ,
M.
Cardoso, A.
D.
Santos , N.
Silva, J.
Ferreira ,
F.
Fernandes.
Ophthalmology, Centro Hospitalar
Lisboa Central, Lisbon , Portugal
6139 — A0318 Combined Pars Plana
Vitrectomy with Gas Tamponade and Posterior
Glaucoma Tube placement in the Management of
Fuchs Heterochromic Iridocyclitis complicated by secondary glaucoma.
Sarah Escott
E. Opremcak 3 .
1
1 , D. Baker ophthalmology, The Wexner
Medical Center Havener Eye Institute, Columbus,
2 ,
OH;
OH;
2
3
Ophthalmology, The Retina Group, Columbus,
Ophthalmology, Ophthalmic Surgeons and
Consultants, columbus, OH
6140 — A0319 Long-term Bleb Survival after
Staged Trabeculectomy and Temporal Clear
Corneal Phacoemulsification versus Combined
Surgery.
Joshua Nunn
3
B. Prum 1
VA; 2
1 , E. Areiter 2, 3 , R. Page
.
1
Lemuel Shattuck Hospital, Boston, MA;
Tulane University, New Orleans, LA
1 ,
University of Virginia, Charlottesville,
6141 — A0320 Trabeculotomy ab externo
Combined with Sinusotomy and with or without
Removal of Schlemm’s Canal Endothelium for
Primary Open Angle Glaucoma and Exfoliation
Glaucoma.
Tadamichi Akagi, H.
Yamada , H.
O.
Ikeda, N.
Unoki, H.
Nakanishi, N.
Yoshimura.
Ophthalmology and Visual Sciences , Kyoto Univ
Graduate Sch of Med, Kyoto, Japan
6142 — A0321 Development of novel glaucoma drainage implant for efficient regulation of intraocular pressure.
MooJong Kim 4 , J. Kang 4
,
,
M. Kim
Y. Kim 1
1, 2 , K. Park
, J. Lee 4, 5 .
1
1, 2 , J. Jeoung 1, 2 , S. Kim 1, 3
Ophthalmology, Seoul
National University College of Medicine, Seoul,
Republic of Korea; 2 Ophthalmology, Seoul
National University Hospital, Seoul, Republic of Korea; 3 Ophthalmology, Seoul National
University Boramae Hospital, Seoul, Republic of
Korea; 4 Nano-Bio Research Center, Korea Institute of Science and Technology, Seoul, Republic of
Korea; 5 Mechanical Engineering, Ajou University,
Suwon, Republic of Korea
6143 — A0322 STARfloTM Glaucoma Implant for surgical treatment of primary open angle glaucoma.
Lukan P.
Mishev , A.
Misheva, A.
Angelov, M.
Ioanna , Y.
Tsankova . Ophthalmology,
Mishevi Eye Center , Sofia, Bulgaria
1
6144 — A0323 A Retrospective Study on the
Effects of Retisert Implant and Ahmed Valve in Patients with Uveitic Glaucoma.
Katherine
Talcott 1 , H. Cho
G. N. Papaliodis
Ophthalmology, Massachusetts Eye and Ear
Infirmary, Boston, MA; 2 of Korea
1, 2
1
, L. Sobrin
, A. Turalba
1
1
, A. Lobo 1 ,
, L. Q. Shen 1 .
Ophthalmology, Hanyang
University College of Medicine, Seoul, Republic
6145 — A0324 Outcomes of Glaucoma
Drainage Implant Surgery in Uveitic
Glaucoma.
Eun S. Huh, D. Sambhara, A. Aref, T.
S. Vajaranant, J. T. Wilensky. Ophthalmology, Univ of Illinois Eye & Ear Infirmary, Chicago, IL
6146 — A0325 Preliminary Results of Tube-
Shunt Coverage with Gamma-irradiated Cornea
Allograft (VisionGraft).
Priyamvada M.
Pitale ,
F.
Ekici, M.
R.
Moster , V.
Cvintal, W.
D.
Hu , M.
Waisbourd.
Glaucoma research , Wills Eye Hospital ,
Philadelphia , PA *CR
6147 — A0326 Miniature Glaucoma Shunt
Implantation after Keratoplasty.
Jasbeth Ledesma
Gil, L.
Gurria , J.
Valencia Aguirre, A.
Navas, E.
O.
Graue, C.
Hartleben-Matkin . Glaucoma , Institute of Ophthalmology, Conde de Valenciana , Mexico
City , Mexico
6148 — A0327 Pars Plana Glaucoma Tube
Drainage Device Implantation Combined with
Vitrectomy and 20% SF6 Gas Tamponade for Treatment of Uncontrolled Uveitic
Glaucoma in Patients with Juvenile Idiopathic
Arthritis.
Megan Chambers , N.
Baker, E.
Opremcak , R.
Derick . Ophthalmology, Ohio State
University , Columbus , OH f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
401

Thursday Posters 12:00 pm – 1:45 pm
6149 – 6171 – Thursday – Posters
6149 — A0328 Fibrinous uveitis following stent suture removal in patients with Baerveldt tube implant.
Laura Beltran-Agullo 1
Galvis
Spain;
2
2
, K. Lim 2 .
1
, S. Jones
St Thomas, London, United Kingdom
2 , E.
Institut Catala Retina, Barcelona,
6150 — A0329 Efficacy of Goniosynechialysis for Advanced Chronic Angle-Closure
Glaucoma.
Guoping Qing . Beijing Tongren Eye
Center , Beijing Tongren Hospital , Beijing, China f
6151 — A0330 Long term outcome of patients with Plateau Iris Configuration.
Jonathan
M.
Schulhof , J.
B.
Serle.
Department of
Ophthalmology, Icahn School of Medicine at Mount
Sinai, New York , NY
6152 — A0331 Short-Term Outcomes Of
Iridoplasty In Persistent Angle Closure Despite
Patent Iridotomies: An Anterior Segment Optical
Coherence Tomography Study.
Jorge-Emmanuel
Morales-León , C.
Elizondo Olascoaga, K.
Dueñas -
Ángeles, A.
Gabriel-Mendoza, E.
O.
Graue, C.
Hartleben-Matkin . Instituto de Oftalmologia
Fundación Conde de Valenciana IAP, Mexico City ,
Mexico
6153 — A0332 Bilateral Same-Day Laser
Peripheral Iridotomy in a Community-
Based Glaucoma-Screening Project in
Philadelphia.
Michael Waisbourd, R.
Delvadia , H.
Sembhi , L.
A.
Hark , L.
Katz . Glaucoma Research
Center , Wills Eye Hospital , Philadelphia , PA *CR
6154 — A0333 Safety and Efficacy of
Selective Laser Trabeculoplasty in Uveitic
Glaucoma.
Pranav Patel, C.
Foster . Massachusetts
Eye Research and Surgery Institute ( MERSI) ,
Cambridge, MA
6155 — A0334 Outcomes of Micropulse
Laser Trabeculoplasty vs. Selective Laser
Trabeculoplasty.
Peter Coombs , N.
M.
Radcliffe.
Ophthalmology, Weill Cornell Medical College,
New York , NY *CR
6156 — A0335 Selective Laser Trabeculoplasty as Initial Therapy in Community Ophthalmology
Offices.
Sophia Y. Siu 1 , A. B. Theventhiran 1 ,
M. Tripoli 4 , S. Luminais 2 , R. L. Sherry 3 ,
D. Yu 5 , J. D. Henderer 1 .
1 Ophthalmology,
Temple University Hospital, Philadelphia,
PA; 2 LevinLuminaisChronister Eye Associates,
Thorndale, PA; 3 Brandywine Eye Center,
Wilmington, DE; 4 Crozer Chester Medical
Center, Upland, PA; 5 Department of Clinical
Sciences, Temple University School of Medicine,
Philadelphia, PA
6157 — A0336 The efficacy of selective laser trabeculoplasty (SLT) in primary angle closure glaucoma (PAC/PACG): a case control study.
Ohoud A.
Owaidhah , L.
Ali Aljasim, D.
P.
Edward . Glaucoma , King Khaled Eye Specialist
Hospital , Riyadh , Saudi Arabia
6158 — A0337 A Comparison of Topical
Steroids Versus Non-Steroidal Anti-
Inflammatory Drugs after Selective Laser
Trabeculoplasty.
Adam L.
Rothman
Delwadia 2 , R. Sarwal
L. W. Herndon 1
3 , S. S. Stinnett
, P. Challa 1 . 1
1
1 , N. A.
, P. P. Lee 4 ,
Ophthalmology, Duke
University School of Medicine, Durham, NC;
University, Durham, NC; 3
Care, P.C., Brentwood, NY; 4
2
University of Michigan
Kellogg Eye Center, Ann Arbor, MI *CR , f
Duke
Long Island Eye Surgical
6159 — A0338 Influence on Intraocular
Pressure of Different Types of Anti-
Inflammatory Treatments after Selective Laser
Trabeculoplasty in Patients with Primary
Open-Angle Glaucoma.
Sophie Champagne 1, 2 , I.
Savoie 1, 2 , J. Anctil 1, 2 , A. Goyette 1, 2 , C. Lajoie 1, 2 , B.
Des Marchais 1, 2 .
1 Département d’ophtalmologie,
Faculté de médecine, Université Laval, Quebec,
QC, Canada; 2 Centre universitaire d’ophtalmologie et Centre de recherche du CHU de Québec, Hôpital du Saint-Sacrement, Quebec, QC, Canada f
6160 — A0339 Repeatability of Selective Laser
Trabeculoplasty.
Julia K.
Polat, T.
Realini.
WVU
Eye Institute, Morgantown , WV *CR
6161 — A0340 Changes in Corneal
Endothelium on Specular Microscopy after
Selective Trabeculoplasty.
Mariem Abidar 1, 2 ,
P. Harasymowycz 1, 2 , G. Li 1, 2 , M. R. Lesk 1, 2 , M.
M. Alotaibi 1 .
1 Ophthalmology, University of
Montreal, Montreal, QC, Canada; 2 Ophthalmology,
Maisonneuve-Rosemont Hospital, Montreal, QC,
Canada
6162 — A0341 Investigation of Corneal
Endothelial Changes Post Selective Laser
Trabeculoplasty.
Di Girolamo
White 4, 5
3
Kate E. Leahy
, S. L. Watson
1, 2 , M. Sarris 3
4 , P. J. McCluskey 4
, N.
, A. J.
Department of Ophthalmology, Westmead .
1
Hospital, Sydney, NSW, Australia;
NSW, Australia; 3
2 Sydney
Medical School, University of Sydney, Sydney,
School of Medical Sciences,
University of New South Wales, Sydney, NSW,
Australia; 4 Save Sight Institute, University of
Sydney, Sydney, NSW, Australia; 5 Westmead
Millennium Institute, University of Sydney, Sydney,
NSW, Australia
6163 — A0342 SLT (Selective Laser
Trabeculoplasty) induced Keratitis.
Annapurna
Singh 1 , M. Belyayev 4 , A. M. Solish 2 , J.
Ruderman 3 .
1 Department of Ophthalmology, Cole
Eye Institute, Cleveland, OH; 2 Southern California
Glaucoma Consultants, University of California,
Los Angeles, CA; 3 Northwestern University,
Feinberg School of Medicine, Chicago, IL; 4 Dept of
Ophtahlmology, Case Western Reserve University,
Cleveland, OH
6164 — A0343 Central corneal thickness as a risk factor in visual field progression in Mexican patients with glaucoma.
Lizbeth Ordoñez, J.
Jimenez-Arroyo , G.
Lazcano, N.
Juárez Reyna, R.
Saucedo, J.
Jimenez-Roman.
Asociación para Evitar la Ceguera en Mexico , Distrito Federal, Mexico
6165 — A0344 Micropulse Diode Laser
Trabeculoplasty Results In Treatment Of
Primary Open-Angle Glaucoma Patients.
Enyr
S.
Arcier i 1, 2 , R. S. Arcieri 3 . 1 Ophthalmology,
Presidente Antônio Carlos University (UNIPAC),
2 Ophthalmology, Federal Araguar, Brazil;
University of Uberlandia (UFU), Uberlandia,
Brazil; 3 Ophthalmology, School of Medicine of
Ribeirao Preto, University of Sao Paulo (USP),
Ribeirao Preto, Brazil
6166 — A0345 Impact of Glaucoma Type on the Success of Transscleral Diode Laser
Cyclophotocoagulation in the Treatment of
Refractory Glaucoma.
Samantha S.
Dewundara,
B.
Hughes , S.
Nagori , A.
Shukairy , J.
Tannir , A.
Goyal, M.
S.
Juzych , C.
Kim.
Ophthalmology,
Kresge Eye Institute, Detroit, MI
6167 — A0346 A LED based device for transscleral photodynamic ablation of the ciliary body in rabbits using Verteporfin.
Miltiadis
K.
Tsilimbaris, R.
Niavi, O.
Sahin, C.
Tsika, I.
Naoumidi . Ophthalmology, University of Crete
Medical School , Heraklion, Greece *CR
6168 — A0347 Trans-scleral Cyclodiode laser for the treatment of plateau iris.
Marina Syrimi ,
M.
Griffiths.
Frinmley Park Hospital , Frimley,
United Kingdom
6169 — A0348 Phaco endoscopic cytophotocoagulation versus phaco external cyclodiode.
Anita Arora 1, 2
Goyal 1, 2 .
1
London, United Kingdom;
, I. Rodrigues
Ophthalmology, St Thomas’ Hospital,
2
2 , S.
Ophthalmology, Queen
Mary’s Hospital, Sidcup, Kent, United Kingdom
6170 — A0349 Multicenter Clinical Trial of Ultrasonic Circular Cyclo Coagulation in patients with Open-Angle Glaucoma:
One Year Results.
Florent Aptel 1 , P. Denis 2 , J.
Rouland 3 , J. Nordmann 4 , Y. Lachkar 5 , J. Renard 6 ,
E. Sellem 7 , C. Baudouin 4 , A. M. Bron 8 .
1 Grenoble
University Hospital, Grenoble, France; 2 Hôpital de la Croix-Rousse, Hospices Civils de Lyon,
Lyon, France; 3 Hôpital Claude Huriez, CHRU de
Lille, Lille, France; 4 Centre Hospitalier National des Quinze-Vingts, Paris, France; 5 Institut du glaucome, Fondation Hôpital Saint-Joseph, Paris,
France; 6 Hôpital d’Instruction des Armées du Val de Grâce, Paris, France; 7 Centre Ophtalmologique
Kléber, Lyon, France; 8 Hôpital Général, Dijon,
France *CR , f
6171 — A0350 High-intensity focused ultrasound device in refractory Glaucoma patients. Results at 1 year.
Shlomo Melamed,
M.
M.
Goldenfeld , D.
Cotlear.
Ophthal/Glaucoma
Unit GEI, Goldschleger Eye Institute, Raanana,
Israel *CR, f
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
402

Thursday – Posters – 6172 – 6194
Exhibit/Poster Hall SA B0077-B0104
Thursday, May 08, 2014 12:00 PM-1:45 PM
Visual Neuroscience
Moderator: Mary A. Johnson
6172 — B0077 Analysis of SIRT3 function in the mouse retina.
Norimitsu Ban 1, 2 , T. Inaba 2 , S.
Miyake
Japan; 2
Japan
1, 2 , K. Tsubota 2 , Y. Ozawa 1, 2 .
1 Laboratory of
Retinal Cell Biology, Keio University, Shinjyuku,
Ophthalmology, Keio University, Shinjyuku,
6173 — B0078 Electrophysiological and
Histological Characterizations of Retinal
Changes in a Mouse Model of Sanfilippo
Syndrome.
Dennis Y. Tse
.
1
1 , P. Lotfi 2 , D. L. Simons 1
Dept of Ophthalmology,
,
M. Sardiello 2 , S. M. Wu 1
Baylor College of Medicine, Houston,
TX; 2 Department of Human and Molecular
Genetics, Neurological Research Institute, Baylor
College of Medicine, Houston, TX
6174 — B0079 Morphology of the Retina in Early Diabetes. J. Beckman, J. M. Moore-
Dotson, M. J. Romero-Aleshire, H. L. Brooks and E.D. Eggers. Physiology and Biomedical
Engineering, University of Arizona, Tucson,
AZ.
Jamie Beckman 1 , J. Moore-Dotson 1 , E. D.
Eggers 1, 2 , M. Romero-Aleshire 1
1
, H. Brooks 1 .
Physiology, University of Arizona, Tucson, AZ;
2 Biomedical Engineering, University of Arizona,
Tucson, AZ
6175 — B0080 Retinal Physiology Is Altered In
Glucose-Treated Zebrafish Retinas.
Victoria P.
Connaughton 1 , Z. Tanvir 1 , R. F. Nelson 2
American University, Washington, DC; 2
. 1 Biology,
Neural
Circuitry Unit, NINDS/NIH, Bethesda, MD
6176 — B0081 Visual impairment in mice expressing glaucoma-associated E50K mutant optineurin.
Henry Tseng 1 , T. Riday 2 , H. Bomze 1 ,
I. Barak 1 , C. Marean-Reardon
Ehlers 3
Durham, NC; 2
1 , B. Philpot 2 , M.
.
1 Ophthalmology, Duke Eye Center,
Cell and Molecular Physiology,
University of North Carolina, Chapel Hill,
NC; 3 Neuroscience Research Unit, Pfizer, Inc,
Cambridge, MA *CR
6177 — B0082 Visual phenotyping of Wfs1 mutant mice, models of Wolfram syndrome neuronal and diabetic symptoms.
Cecile Delettre 1
C. P. Hamel , S. Koks 2 , M. Seveno 1
Montpellier, France;
Estonia
1
D. M. Bonnet Wersinger
2
1 .
1
, G. Lenaers 1
INSERM U1051,
University of Tartu, Tartu,
,
,
6178 — B0083 Collagen 4a1 deficiency induces a vascular leakage in the retina.
Alix
Trouillet 1
I. Ivkovic
A. Sahel
France; 2
1
, E. Plaisier 2
1
, B. El Mathari
, J. Degardin 1
, S. A. Picaud 1
, M. Paques 1
1 , H. Lorach
, P. Ronco 2
1 ,
, J.
.
1 Institut de la Vision, Paris,
APHP- Hopital Tenon, Paris, France
6179 — B0084 Characterization of a refined mouse model of retinal vein occlusion.
Andreas
Ebneter, C.
Agca , S.
Wolf , V.
Enzmann, M.
S.
Zinkernagel.
Department of Ophthalmology,
University of Bern , Bern , Switzerland *CR
6180 — B0085 Corneal ERG Topography in Healthy Rat Eyes and Eyes with Focal
Retinal Lesions.
Zahra Derafshi 1 , H.
Tajalli 1 , S. Thongpang 2 , J. Williams 2 , J. R.
Hetling 1 .
1 Bioengineering, University of Illinois at
Chicago, Chicago, IL; 2 Biomedical Engineering,
University of Wisconsin-Madison, Madison,
WI *CR
6181 — B0086 Electroretinogram Findings in Animal Model of Concurrent Diabetes and Hypothyroidism.
Bruno D. Gomes 1
Guimarães 1 , N. F. Rabelo 1 , M. Hamoy
1, 2 , A. M. Herculano
1
1
, G. F.
, L. L.
.
1 Silveira 1 , F. F. Rocha Instituto de Ciências Biológicas, Universidade Federal do
Pará, Belém, Brazil; 2 Núcleo de Medicina Tropical,
Universidade Federal do Pará, Belém, Brazil
6182 — B0087 A familial abnormal negative photopic ERG in Papillon dogs.
Simon M.
Petersen Jones, K.
J.
Gervais, P.
A.
Winkler, F.
M.
Mowat, L.
M.
Occelli, J.
T.
Bartoe . Small Animal
Clinical Sciences , Michigan State University , East
Lansing, MI
6183 — B0088 Dietary ω3 fatty acids & metabolic syndrome in the rat : consequences on sensitivity and retinal functionality.
Magalie
Thierr y 1 , B. Pasquis 2 , V. Febvret
L. Leclère
Bron 1, 3
1 , N. Acar
, L. Bretillon 1 . 1
1 , S. Grégoire 1
1 , C. P. Garcher 1, 3 , A. M.
,
Eye, Nutrition & Signalling
Research, CSGA, UMR 1324 INRA, 6265 CNRS,
University of Burgundy, Dijon, France; 2 Animalerie expérimentale, CSGA, UMR 1324 INRA,
6265 CNRS, University of Burgundy, Dijon,
France; 3 Department of Ophtalmology, University
Hospital, Dijon, France
6184 — B0089 Photoreceptor and postphotoreceptoral contribution to reduction of photopic b-wave ERG in light-adapted
Pikachurin null-mutant mice.
Masatoshi
Nagaya 1 , S. Ueno 1 , M. Kondo 2 , T. Furukawa 3 , H.
Terasaki 1 .
1 Ophthalmology, Nagoya University
Graduate School of Medicine, Nagoya,
Japan; 2 Ophthalmology, Mie University Graduate
School of Medicine, Tsu, Japan; 3 Institute for
Protein Research, Osaka University, Osaka, Japan
6185 — B0090 Effects of Quensyl on the ERG a-wave amplitude from the isolated superfused vertebrate retina.
Siarhei Siapich, A.
Goebel , P.
Walter . RWTH UKAachen , Aachen , German y
6186 — B0091 Differentiating between
Ischemic and Non-Ischemic Origins of the
“Negative” Electroretinogram.
Naoyuki
Tanimoto 1 , J. D. Akula 2 , A. Fulton 2 , B. H.
Weber 3 , M. W. Seeliger 1 . 1 Division of Ocular
Neurodegeneration, Ctr Ophthalmol Inst
Ophthalmic Res, Tuebingen, Germany; 2 Department of Ophthalmology, Boston Children’s Hospital and
Harvard Medical School, Boston, MA; 3 Institute of Human Genetics, University of Regensburg,
Regensburg, Germany
6187 — B0092 The neuroprotection of
Angiotensin-(1-7) in Tg(RHO P347S) and rd10 mice.
Ping Zhu, P.
K.
Shil , W.
Deng , J.
Li , A.
Verma, T.
Prasad , Q.
Li . Ophthalmology, University of Florida, Gainesville, FL
6188 — B0093 Non-metric Multidimensional
Scaling of Electroretinogram Oscillatory
Potential Data achieves Early Diagnosis of
Retinal Degeneration in a Mouse Model of
Mitochondrial Dysfunction.
Eric Dolinar 1
MacPherson
Hutnik 2
1 , A. Laliberté
, K. Hill 1 .
1
1 , J. Van Gaalen
Ontario, London, ON, Canada;
1
, T.
, C. M.
Biology, University of Western
2 Ivey Eye Institute,
London Health Sciences Center, London, ON,
Canada
6189 — B0094 Daily optokinetic testing improves contrast sensitivity through BDNFmediated pathways.
Amanda Mui
H. Aung 1, 2 , T. Obertone
.
1
1 , H. Park 1
1 , B. C. Prall 2 , M.
, J. H. Boatright 1 ,
Ophthalmology, Emory University, M. T. Pardue 1, 3
Atlanta, GA;
Atlanta, GA;
Atlanta, GA
2
3
Neuroscience, Emory University,
Veterans Affairs Medical Center,
6190 — B0095 Spatiotemporal mapping of retinal phototropic response evoked by oblique light stimulation.
Xincheng Yao, R.
Lu , B.
Wang ,
Q.
Zhang.
Biomedical Engineering, Univ of
Alabama at Birmingham , Birmingham , AL *CR
6191 — B0096 Anesthesia usage confounds in vivo pharmacological studies using electrophysiology.
Jason Charng
Vingrys 1 , B. V. Bui
T. Nguyen 1 . 1
1 , R. L. Fish 2
1 , Z. He 1 , A. J.
, R. Gurrell 2 , C.
Optometry and Vision Sciences, The
2
University of Melburne, Melbourne, VIC, Australia;
Pfizer Neusentis, Cambridge, United Kingdom *CR
6192 — B0097 Long-term bilateral microglial responses in rat retina after unilateral optic nerve transection.
Ling Ping Cen, M.
Hang , M.
Zhang.
Joint Shantou International Eye Center ,
Shantou, China
6193 — B0098 Characterization of light toxicity on retinal ganglion cells in vivo and in vitro.
Emilie Arnault 1, 2
P. Gondouin
Villette 3
Picaud 1, 2 .
1
1, 2
U968, INSERM, Institut de la Vision,
Paris, France; 2
, C. Nanteau 1, 2
, C. Barrau
, K. Bigot
, D. A. Cohen-Tannoudji 3
1, 2
, J. Sahel
3 ,
, T.
1, 4 , S. A.
UMR_S968, UPMC Université Paris
06, Institut de la Vision, Paris, France; 3 Essilor
International, Charenton-le-Pont, France; 4 Centre
Hospitalier National d’Ophtalmologie des Quinze-
Vingts, Paris, France *CR
6194 — B0099 Determination of Injury
Thresholds for Torsional Indirect Traumatic
Optic Neuropathy in a Rat Model.
Brooke I.
Asemota 2 , W. E. Sponsel 1 1 , R. D. Glickman
Reilly 1 . 1
Texas at San Antonio, San Antonio, TX; 2
, M. A.
Biomedical Engineering, University of
Antonio, TX
University of Texas Health Science Center at San Antonio, San f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
403

Thursday Posters 12:00 pm – 1:45 pm
6195 – 6208 – Thursday – Posters
6195 — B0100 Heat shock protein 25 kDa gene therapy alleviates retinal ganglion cell dysfunction after optic nerve crush in mice.
Henri
O.
Leinonen 1 , S. Ragauskas 2, 3 , J. Puranen 2 , A.
6
Smedowski 2, 4 , K. Airenne 5 , S. Ylä-Herttuala 5,
, H. Tanila 1 , G. Kalesnykas 2, 7 . 1 Department of
Neurobiology, A.I. Virtanen institute, University of Eastern Finland, Kuopio, Finland; 2 Department of Ophthalmology, Institute of Clinical Medicine,
School of Medicine, University of Eastern
Finland, Kuopio, Finland; 3 Institute of Innovative
Medicine, Vilnius, Lithuania; 4 Department of Physiology, Medical University of Silesia,
Katowice, Poland; 5 Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute,
University of Eastern Finland, Kuopio,
Finland; 6 Research Unit and Gene Therapy
Unit, Kuopio University Hospital, Kuopio,
Finland; 7 Experimentica Ltd., Kuopio, Finland *CR
3
6196 — B0101 Morphological and functional evaluation of retinal ganglion cells in R6/2 mice.
Symantas Ragauska s
J. Puranen 1
Gurevicius
Tanila 3
3
, S. Nymark 4
, O. Kontkanen 5
, G. Kalesnykas 1, 6
Kuopio, Finland;
. 1
Institute, Kuopio, Finland;
1, 2 , H. O. Leinonen 3
, A. Lipponen 3 , K.
, J. Puoliväli 5 , H.
Department of
Ophthalmology, University of Eastern Finland,
2 State Reaserch Institute for Innovative Medicine, Vilnius, Lithuania;
Department of Neurobiology, A.I. Virtanen
4 Department of
,
Electronics and Communications Engineering,
BioMediTech, Tampere University of Technology,
Tampere, Finland; 5
Kuopio, Finland; 6
Charles River DRS Finland,
Department of Ophthalmology,
Kuopio University Hospital, Kuopio, Finland
6197 — B0102 Targeted modulation of the glial inflammatory response in Retinitis Pigmentosa attenuates photoreceptor cell death.
Enrique J.
de la Rosa 1 , C. Hernández-Sánchez 1 , A. M. Hernández-
Pinto 1 , M. Platón 1 , M. Marchena 1 , N. Álvarez-
Lindo 1 , A. I. Arroba 1 , S. Jmaeff 2 , P. F. Barcelona 2 , H.
Saragovi 2 . 1 Cell & Molecular Medicine, Centro de
Investigaciones Biologicas, Madrid, Spain; 2 Lady
Davis Institute-Jewish General Hospital Montreal,
McGill University, Montreal, QC, Canada *CR
6198 — B0103 Changes of Receptive Field
Properties of Ganglion Cells in a Rat Model of
Retinitis Pigmentosa.
Wan-Qing Yu
Field 3, 4 , N. Grzywacz 1, 2 .
1
, E. Lee
Neuroscience Graduate
Progam, University of Southern California,
Los Angeles, CA; 2
Los Angeles, CA; 3
1 2
Department of Biomedical
, G.
Engineering, University of Southern California,
Zilkha Neurogenetic Institute,
University of Southern California, Los Angeles,
CA; 4 Department of Cell and Neurobiology,
University of Southern California, Los Angeles, CA
6199 — B0104 Brimonidine Enhances
Electrophysiological Activity of Retinal Ganglion
Cells through Trk-PI3K Pathway.
Masayoshi
Yukita 1 , S. Machida 2 , K. Omodaka 1 , K. Maruyama 1 ,
T. Nakazawa 1 .
1 Ophthalmology, Tohoku University
Graduate School of Medicine, Miyagiken,
Japan; 2 Ophthalmology, Iwate Medical University
School of Medicine, Iwateken, Japan
Exhibit/Poster Hall SA B0119-B0156
Thursday, May 08, 2014 12:00 PM-1:45 PM
Eye Movements / Strabismus / Amblyopia /
Neuro-Ophthalmology / Retina
Moderator: Alfredo A. Sadun
6200 — B0119 Genetic survey of primary
LHON-causing mtDNA mutations as well as
OPA1 and OPA3 mutations in 522 Chinese families with suspected hereditary optic neuropathy.
Yang Li, J. Chen, X. Zhang, K. Xu,
B. Dong. Beijing Inst of Ophthalmology, Beijing
Tongren Hospital, Beijing, China
6201 — B0120 EPI-743 May Improve Visual
Acuity in LHON: Data from a Brazilian
Cohort.
Karanjia 1
Amitha K. Ganti
, J. Tran 1
A. Berezovsky 2
1 , E. R. Chu
, R. Belfort, Jr.
2
1 , R.
, M. Moraes
, A. A. Sadun 1 , G. Miller 4
2, 3
Chicani 2 .
1
,
, F.
Ophthalmology, University of Southern
California, Los Angeles, CA; 2 Ophthalmology,
Universidade Federal de São Paulo, São Paulo,
Brazil; 3 Centro Universitario do Espirito Santo,
Colatina, Brazil; 4 Edison Pharmaceuticals,
Mountain View, CA *CR
6202 — B0121 Perimetric parameters in unaffected carriers of Leber’s Hereditary Optic
Neuropathy (LHON).
Andrew Pouw 1 , J. Gale 1 , R.
Karanjia
A. Berezovsky 3
Sadun 1
1 , J. Tran 1 , M. Moraes 2, 3 , S. R. Salomao 3
, F. Chicani 3 , P. A. Quiros 1
.
1 Ophthalmology, University of Southern
California, Los Angeles, CA; 2 do Espirito Santo, Colatina, Brazil;
, A. A.
,
Centro Universitario
3 Ophthalmology,
Federal University of Sao Paulo, Sao Paulo, Brazil
6203 — B0122 Although smoking and alcohol are known to increase incidence of Leber’s
Hereditary Optic Neuropathy (LHON) only smoking increases severity of LHON.
Rustum
Karanjia
University of Southern California, Los Angeles,
CA; 2
1 , J. Tran
Frousiakis 1
S. R. Salomao 3
Colatina, Brazil; 3
1 , E. R. Chu 1
, A. Pouw 1
, J. Gale
, C. A. Wa
, V. Carelli 4, 5 . 1
1
1 , S. E.
, M. Moraes
Ophthalmology,
Centro Universitario do Espirito Santo,
Ophthalmology, Federal
University of Sao Paulo, Sao Paulo, Brazil;
2, 3 ,
Bellaria Hospital, Bolongna, Italy;
4 IRCCS
Institute of Neurological Sciences of Bologna,
5 Department of
Biomedical and NeuroMotor Sciences (DIBINEM),
University of Bologna, Bolongna, Italy
6204 — B0123 Multifocal bioelectrical cortical responses in Leber Hereditary Optic
Neuropathy.
Vincenzo Parisi 1 , L. Ziccardi 1 , D.
Giannini 2 , F. Sadun 3 , A. De Negri 4 , G. Savini 5 , P.
Barboni 6, 7 , C. La Morgia 8, 9 , V. Carelli 8, 9 .
1 Visual
Neurophysiology & Neurophthalmology, GB Bietti
Eye Foundation-IRCCS, Rome, Italy; 2 Department of Statistical Sciences, “Sapienza” University of
Rome, Rome, Italy; 3 Ophthalmology, Saint John
Evangelist Hospital, Tivoli, Italy; 4 Ophthalmology,
5
Azienda San Camillo-Forlanini, Rome, Italy;
Anterior Segment Unit, GB Bietti Eye Foundation
- IRCCS, Rome, Italy; 6 Ophthalmology, Ophthalmic
Clinic d’ Azeglio, Bologna, Italy; 7 Ophthalmology,
Scientific Institute San Raffaele -IRCCS, Milan,
Italy; 8 Neurology, Institute of Neurologic Sciences of Bologna - IRCCS, Bologna, Italy; 9 DIBINEM,
University of Bologna, Bologna, Italy
6205 — B0124 Cardiac Conduction in Leber’s
Hereditary Optic Neuropathy.
Starleen E.
Frousiakis
Quiros 1
1 , R. Karanjia
M. Moraes 2, 3
, F. Chicani 3
1 , A. K. Ganti
, S. R. Salomao 3
, A. A. Sadun 1 .
1
1 , A. Pouw 1
, R. Belfort, Jr.
3
University of Southern California, Los Angeles,
,
, P. A.
Ophthalmology,
CA; 2 Centro Universitario do Espirito Santo,
Colatina, Brazil; 3 Department of Ophthalmology,
Federal University of Sao Paulo, Sao Paulo, Brazil
6206 — B0125 Clinical experience with
Idebenone (Raxone ® ) in the treatment of patients with Leber’s Hereditary Optic Neuropathy
(LHON).
Guenther Metz 1 , C. Gallenmueller 2 , T.
Meier 1 , T. Klopstock 2 .
1 Santhera Pharmaceuticals
(Switzerland) Ltd, Liestal, Switzerland; 2 Neurology,
Friedrich-Baur-Institute, Ludwig-Maximilians-
University, Munich, Germany *CR
6207 — B0126 Long Pcr Based Analysis Of
Whole Mitochondrial Genome Of Leber’s
Hereditary Optic Neuropathy (Lhon) Patients.
Bibhuti B. Saikia
Shanmugam 2
1 , J. Charmakani
, P. Sundaresan 1 . 1
1 , M. K.
Department of
Genetics, Aravind Medical Research Foundation,
Madurai, India; 2 Neuro-ophthalmology Clinic,
Aravind Eye Hospital and Post Graduate Institute of
Ophthalmology, Madurai, India
6208 — B0127 The mt11778/ND4 mutation, in Leber’s hereditary optic neuropathy, is associated with less degeneration in the peripheral nerve compared to the mt3460/ND1 mutation.
Edward R. Chu 1 , F. N. Ross-Cisneros 1 ,
A. H. Pham 1 , J. Gale 1 , M. Moraes 2, 3 , S. R.
Salomao 3 , A. Berezovsky 3 , V. Carelli 4, 5 , R. Belfort,
Jr.
3 , A. A. Sadun 1 .
1 Ophthalmology, Keck School of Medicine, University of Southern California,
Los Angeles, CA; 2 Centro Universitário do
Espírito Santo, Colatina, Brazil; 3 Ophthalmology,
Federal University of Sao Paulo, Sao Paulo,
Brazil; 4 Neurological Sciences, University of Bologna, Bologna, Italy; 5 Biomedical and
NeuroMotor Sciences, University of Bologna,
Bologna, Italy *CR
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
404

Thursday – Posters – 6209 – 6231
1
6209 — B0128 Mitochondrial DNA integration and replication in transgenic mutant ND4 mice.
John Gu y
Bascom Palmer Eye Institute, University of Miami,
Miami, FL; 2
Miami, FL; 3
1 , H. Yu 1 , A. Mehta 2 , A. S. Lewin 3 .
Hussman Institute Human Genomics,
University of Florida, Gainesville, FL
6210 — B0129 Multiethnic involvement in autosomal dominant optic atrophy; report of a new gene mutation causing optic atrophy and deafness.
Dan Milea 1, 2
Tow 1
Loo 1
, D. Bonneau 2
.
1
Singapore; 2
France
, P. Amati-Bonneau
, V. Procaccio 2
2 , S.
, P. Reynier 2 , J.
Singapore National Eye Centre, Singapore,
Angers University Hospital, Angers,
6211 — B0130 Macular Sensitivity and
Fixation Patterns in Patients with Autosomal
Dominant Optic Atrophy.
Larsen 1, 2 .
1
Copenhagen, Denmark
Cecilia Ronnback
Hospital, Glostrup, Copenhagen, Denmark; 2
1, 2
Faculty of Health Sciences, University of Copenhagen,
, M.
Department of Ophthalmology, Glostrup
6212 — B0131 Ganglion cell complex analysis in toxic optic neuropathy by optical coherence tomography.
luisa vieira , N.
Silva, A.
D.
Santos ,
R.
Anjos, L.
Abegão Pinto, A.
Vicente, B.
Borges ,
J.
Ferreira , D.
Amado, J.
Cunha.
Centro Hospitalar
Lisboa Central, lisboa , Portugal
6213 — B0132 The electrophysiological characteristics and monitoring of ethambutol toxicity.
Anthony G.
Robson 1, 2
S. Li 3 , M. M. Neveu
Holder 1, 2 .
1
Kingdom; 3
1, 2 , Z. Q. Yin 3 , G. E.
Electrophysiology, Moorfields Eye
Hospital, London, United Kingdom; 2
Southwest Eye Hospital, Third Miltary
Medical University, Chongqing, China
,
Institute of Ophthalmology, UCL, London, United
6214 — B0133 Reversible changes in patients with early detected ethambutol induced ocular toxicity : after discontinuation of ethambutol treatment.
Kyoung Lae Kim, S. Park.
Ophthalmology, Kangdong sacred heart hospital,
Hallym university, Seoul, Republic of Korea
6215 — B0134 Evaluation of circumpapillary retinal nerve fiber layer from nasal hemiretina.
Kaori Ueda , A.
Kanamori , Y.
Matsumoto, A.
Akashi , Y.
Yamada , M.
Nakamura .
Division of Ophthalmology, Department of , Kobe
University Graduate School of Medicine , Kobe ,
Japan f
6216 — B0135 Prevalence and
Characterization of Epiretinal Membranes in Patients with Optic Nerve Disease.
Nicole
De Cuir
Moraes 1
1 , J. Idiga 1
, R. Ritch 2
, K. Kaur 1 , J. Odel 1
, D. C. Hood 1 . 1
, G. V. De
Columbia
University, New York, NY; 2 New York Eye & Ear
Infirmary, New York, NY *CR
6217 — B0136 Ocular findings and handheld optical coherence tomography in microcephaly.
Eleni Papageorgiou
Proudlock
Gottlob 1 . 1
1 , V. Sheth 1 , R. Purohit 1
1 , H. Lee 1 , F. A.
, P. Vasudevan 2 , I.
Ophthalmology, University of Leicester,
Leicester, United Kingdom; 2 Clinical Genetics,
University of Leicester, Leicester, United Kingdom
6218 — B0137 Sectorial macular retinal ganglion cell layer thinning caused by retrograde degeneration of the visual pathway.
Bernardo
F. Sanchez Dalmau 1, 2 , J. Keller 1 , P. Villoslada 2 .
1 Institut Clinic d’Oftalmologia, Hospital Clinic.
Seu Maternitat, Barcelona, Spain; 2 Center for
Neuroimmunology, IDIBAPS, Barcelona,
Spain *CR
6219 — B0138 Infra-red photography retinal abnormalities and inner nuclear layer microcystic retinal degeneration in eyes with band atrophy of the optic nerve.
Mario
L. Monteiro
N. Rajagopalan
Nguyen 2
1 , R. M. Sousa
2
1 , D. A. Ferraz 1
, M. A. Sadiq 2
, W. Y. Takahashi 1 .
1
, Y. Sepah 2
,
, Q.
Ophthalmology and
Otolaringology, University of São Paulo Medical
School, São Paulo, Brazil; 2 Ophthalmology,
University of Nebraska Medical Center Stanley M.
Truhlsen Eye Institute, Omaha, NE *CR
6220 — B0139 Visual Recovery and OCT
Changes Following Treatment of Nonarteritic
Anterior Ischemic Optic Neuropathy with
Levodopa, Allopurinol and Tetracycline.
Lenworth N. Johnson 1, 2 , D. P. Harris Lyttle 2 , G. F.
Petroski 3 . 1 Ophthalmology, Alpert Medical School of Brown University/Rhode Island Hospital,
Providence, RI; 2 Ophthal-Sch of Med, University of
Missouri-Columbia, Columbia, MO; 3 Biostatistics,
University of Missouri-Columbia, Columbia,
MO f
6221 — B0140 Therapeutic Outcomes of
Traumatic Optic Neuropathy.
Hidetoshi Onda , J.
Kizaki , H.
Okawada, H.
Takahashi, E.
Tomoyori ,
M.
Hirosawa . Ophthalmology, Showa Univ Sch of
Medicine , Shinagawa-Ku , Japan
6222 — B0141 An Experimental Model of Optic Nerve Head Injury.
Dimosthenis
Mantopoulos 1, 2 , A. Tsakris 3 , B. S. Pawlyk 1 , M.
A. Sandberg 1 , J. W. Miller 1 , J. F. Rizzo 1 , D.
G. Vavvas 1 , D. M. Cestari 1 .
1 Ophthalmology,
Massachusetts Eye and Ear Infirmary, Boston,
MA; 2 Ophthalmology, Ohio State University,
Columbus, OH; 3 Microbiology, Athens Medical
School, Athens, Greece
6223 — B0142 Revatio (Sildenafil) protects retinal ganglion cells immediately after optic nerve crush injury, but high dose intraperitoneal may induce sporadic optic nerve stroke.
Nitza
Goldenberg-Cohen 1, 2
D. Morzaev
Zadok 3
, M. Vieyra 2
2 , O. Muhsinoglu
, J. D. Nicholson 2
2
,
.
1
1 , S. Weiss , D.
Ophthalmology, Schneider Childrens
Med Ctr, Petach Tikva, Israel; 2 Sackler School of
Medicine, The Krieger Eye Research Laboratory,
3
FMRC, Tel Aviv University, Petach Tikva, Israel;
Ophthalmology Department, Assaf Harofeh,
Zerifin, Israel
1
6224 — B0143 TrkB Neurotrophin Receptor
Activation with Pharmacophore as Possible
Treatment for Experimental Ischemic Optic
Neuropathy.
M.
Ali Shariati
T. Yang 2 , B. Barres 3
1 , J. Ma
, C. Chakraborty 3
1 , F. Longo
, Y. J. Liao
2
1
,
.
Ophthalmology, Byers Eye Institute at Stanford,
Stanford, CA; 2 Neurology, Stanford School of
Medicine, Stanford, CA; 3 Neurobiology, Stanford
School of Medicine, Stanford, CA *CR
6225 — B0144 Optical coherence tomography measurements of the macular area in eyes with optic nerve sheath meningioma.
Stanley Darma 1 ,
P. Saeed 1 , M. P. Mourits 1 , M. D. Abramoff 2, 3 , F.
D. Verbraak 1 .
1 Ophthalmology, Academic Medical
Center, Amsterdam, Netherlands; 2 Ophthalmology and Visual Sciences, University of Iowa, Iowa
City, IA; 3 Electrical and Computer Engineering,
University of Iowa, Iowa City, IA *CR
6226 — B0145 Early axonal damage detection by Ganglion Cell Complex with Optical
Coherence Tomography in Nonarteritic Anterior
Isquemic Optic Neuropathy.
Begona Arana, B.
Berasategui, A.
Orive, N.
Martínez Alday, M.
Galdós . Cruces , Barakaldo, Spain
6227 — B0146 Severe Impairment of Axonal
Transport in Acute Experimental Anterior
Ischemic Optic Neuropathy.
Jeffrey Ma 1 , M.
Shariati 1 , L. Pisani 2 , F. Pestilli 3 , B. Dougherty 3 ,
L. Perry 3 , G. Lee 1 , C. Contag 2 , B. A. Wandell 3 ,
Y. J. Liao 1 .
1 Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA; 2 Stanford Center for
Innovation in In Vivo Imaging, Stanford, CA;
3 Psychology, Cognitive and Neurobiological
Imaging Center at Stanford, Stanford, CA
6228 — B0147 Assessment of apoptosis along the optic nerve after low-level repeated blast exposure.
B. J. Lund 1
Wang 1 . 1
Jae Hyek Choi 1
, A. J. Johnson 1
, J. Novak 2 , T. A. Burke 1 ,
, J. Cleland 1 , H. H.
Ocular Trauma, UU.S. Army Institute of Surgical Research, JBSA Fort Sam Houston,
TX; 2 Pathology, U.S. Army Institute of Surgical
Research, JBSA Fort Sam Houston, TX
6229 — B0148 Optic nerve changes after mild traumatic brain injury in mice expressing human Tau.
Alexandra Quezada 1 , M. Gautier 1 , B.
Mouzon 1 , J. Ojo 1 , F. Crawford 1, 2 , R. T. Tzekov 1, 2 .
1 Roskamp Institute, Sarasota, FL; 2 VA hospital,
Tampa, FL
6230 — B0149 Links between the endoplasmatic reticulum protein WFS1/
Wolframin and mitochondrial proteins defined in silico may explain optic atrophy.
Rainald G.
Schmidt-Kastner
Medina 1
1 , T. Seidman
, B. Lorenz 2
1 , G. Quinones-
, M. N. Preising 2 .
1 C.E. Schmidt
College of Medicine, Florida Atlantic University,
Boca Raton, FL; 2 Department of Ophthalmology,
Justus-Liebig University, Giessen, Germany
6231 — B0150 Vitamin A Deficiency as a cause of Optic Neuropathy.
Francinia McCartney, M.
Berkenstock, J.
M.
Ackert . Ophthalmology, Drexel
College of Medicine , Philadelphia , PA f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
405

Thursday Posters 12:00 pm – 1:45 pm
6232 – 6253 – Thursday – Posters
6232 — B0151 Effects of Pentoxifylline on
Blood Flow in Patients with Non-Arteritic
Ischemic Optic Neuropathy.
Jesse Gale
E. R. Chu
Karanjia 1
1 , S. E. Frousiakis
, O. Tan
1 , S. Srinivas 2
1 ,
, R.
3 , D. Huang 3 , S. R. Sadda 1
Sadun 1 .
1
California, Los Angeles, CA;
, A. A.
Ophthalmology, University of Southern
2 Doheny Eye Institute,
Los Angeles, CA; 3 Casey Eye Institute, Oregon
Health and Science University, Portland, OR *CR
6233 — B0152 Induction of autophagy protects axons against TNF-induced optic nerve degeneration with possible involvement of p62 inhibition.
Yasushi Kitaoka, K.
Kojima , Y.
Munemasa , H.
Takagi . Ophthalmology, St Marianna
Univ School of Med, Kawasaki , Japan
1
6234 — B0153 Electrophysiological Monitoring in Chidren with Optic Nerve Glioma.
Valeria L.
Fu 2, 1 , E. Mitchell 1, 2 , A. Medsinge 1, 2 , K. Nischal
Pittsburgh, PA; 2 Ophthalmology, University of
Pittsburgh School of Medicine, Pittsburgh, PA
1, 2 .
Ophthalmology, Children’s Hospital of Pittsburgh,
6235 — B0154 Characteristics of Normal
Optic Nerve Development Using Hand-Held
Ultra-High Resolution Spectral Domain Optical
Coherence Tomography in Children and Young
Adults.
Dr Patel, R.
Purohit, H.
Lee, V.
Sheth, G.
Maconachie , E.
Papageorgiou , F.
A.
Proudlock,
R.
J.
McLean , I.
Gottlob.
Ophthalmology Group,
University of Leicester, Leicester, United Kingdom
6236 — B0155 Multifocal Photopic Negative
Response (mfPhNR) and Ganglion Cell-Inner
Plexiform Layer Thickness (GCIPLT) in
Patients with Optic Nerve Lesions.
Ari Kamei 1 ,
E. Nagasaka
Japan; 2
2 .
1 Ari Eye Clinic, Oshu-Mizusawa,
Mayo Corp., Inazawa, Japan
6237 — B0156 Diagnostic ability of macular analysis by SD-OCT for compression optic neuropathy at chiasma.
Azusa Akashi , A.
Kanamori , Y.
Matsumoto, M.
Sakamoto , M.
Naka ,
Y.
Kondo, Y.
Yamada , M.
Nakamura . Kobe university , Kobe , Japan f
Exhibit/Poster Hall SA B0157-B0168
Thursday, May 08, 2014 12:00 PM-1:45 PM
Visual Psychophysics / Physiological Optics
Moderator: James A. Kuchenbecker
6238 — B0157 Effect of color illumination from street lights on scotopic visual acuity.
Kozo
Masuda 1 , H. Uozato 2 . 1 Health and Social Services,
Osaka University of Human Sciences, Settu,
Japan; 2 Ophthalmology/School of Allied Health
Sciences, Kitasato University, Sagamihara, Japan
6239 — B0158 Rod-Cone Interactions in
Mesopic Spatial Vision.
Pablo A.
Barrionuevo,
D.
Cao.
Ophthalmology and Visual Sciences ,
University of Illinois at Chicago, Chicago, IL
6240 — B0159 Hands-Free Phone
Communication Impairs Low Contrast Color and Luminance Target Recognition.
Jeff C.
Rabin, T. Bradshaw, A. Chacon, S. Johnston, D. Yu.
Optometry, UIW Rosenberg School of Optometry,
San Antonio, TX
6241 — B0160 An Alarming and Practical Case of Compromised Color Constancy.
Javid Sadr .
Psychology , University of Lethbridge , Lethbridge ,
AB , Canada
6242 — B0161 Functional Defects
In Colour Vision In Patients With
Choroideremia.
R. E. MacLaren 1, 2
Jasleen K. Jolly
.
1
1, 2 , M. Groppe 1, 2
Nuffield Laboratory of Ophthalmology, Nuffield Department
, of Clinical Neurosciences, Oxford, United
Kingdom; 2 Moorfields Eye Hospital-UCL Institute of Ophthalmolog, NIHR Biomedical Research
Centre, London, United Kingdom *CR , f
6243 — B0162 Color Vision Defects Among
Leprosy Patients With Normal Spatial
Luminance Contrast Sensitivity.
Andrew
S.
Caires 1, 3 , F. Reis 1, 3 , E. B. Lacerda 2, 3 , G. S.
Souza 3, 2 , A. C F Papaleo
A. R. Rodrigues tentes Côrtes 1 . 1
2, 3
4 , L. B do C Azevedo
, L. L. Silveira 2, 3 , M. Izabel
4 ,
Programa de Pós Graduação em Ciências da Saúde, Universidade federal do
Amapá, Macapa, Brazil; 2 Instituto de Ciências
Biológicas, Universidade Federal do Pará, Belem,
Brazil; 3 Nucleo de medicina Tropical, Universidade
Federal do Para, Belem, Brazil; 4 Programa de controle de doenças tropicais, Centro de Referência em Doenças Tropicais, Macapá, Brazil *CR
6244 — B0163 Space And Spatial Frequency
Joint Entropy Estimated From Different
Achromatic And Chromatic Stimuli With
And Without Heterochromatic Flicker
Photometry.
Vladimir A.
Silveira 1, 2
Souza 1, 2
, G. S.
, B. D. Gomes 1 , A. R. Rodrigues
L. Silveira 1, 2
2
Universidade Federal do Pará, Belém,
Brazil; 2
. 1
, L.
Instituto de Ciências Biológicas,
Núcleo de Medicina Tropical, Universidade
Federal do Pará, Belém, Brazil
6245 — B0164 Color Discrimination
Ellipses Estimated Using Colour Assessment
And Diagnosis Test: Preliminary Brazilian
Database And Correlation With Results From
Cambridge Colour Test.
Leticia Miquilini 1 ,
G. S. Souza 1, 2 , E. B. Lacerda
, L. L. Silveira 1, 2
1 , A. Rosa 3, 4 , D. F.
.
1 Instituto de Ciencias Ventura 5
Biologicas, Universidade Federal do Para, Belem,
Brazil; 2 Nucleo de Medicina Tropical, Universidade
Federal do Para, Belem, Brazil; 3
Belem, Brazil; 4
Instituto de
Ciencias da Saude, Universidade Federal do Para,
Hospital Universitario Bettina Ferro de Souza, Universidade Federal do Para, Belem,
Brazil; 5 Instituto de Psicologia, Universidade de Sao
Paulo, Sao Paulo, Brazil
6246 — B0165 The Relationship Between
Photopigment Spectral Separation and Color
Vision Acuity.
Candice Davidoff , M.
Neitz, J.
Neitz.
Ophthalmology, University of Washington ,
Seattle, WA
6247 — B0166 The Effect of Aging on Color
Visual Acuity in Normal Eyes and Tinted-
IOL Eyes.
Nakaura
Horai 1
2
Yoshiki Tanaka
, K. Ichikawa 2
, K. Tanaka 3 .
1
1 , S. Yokoyama 2
, S. Tanabe 2
, H.
, Y. Kato 2 , R.
Medical Support, Chukyo
Medical Co., Inc., Nagoya, Japan; 2 Ophthalmology,
Social Insurance Chukyo Hospital, Nagoya,
Japan; 3 Faculty of Engineering, Shinshu University,
Nagano, Japan
6248 — B0167 Chromatic components in underwater targets do not affect Great cormorants’ (Phalacrocorax carbo) visual resolution.
Gadi Katzir 1, 2 , R. Almon 1 , I.
.
1 Izhaki 1 Department of Evolutionary and
Environmental Biology, University of Haifa, Haifa,
Israel; 2 Department of Marine Biology, University of Haifa, Haifa, Israel
6249 — B0168 Spatial retinal reflectance properties and red-green relative spectral sensitivity.
Dimitrios Christaras , H.
S.
Ginis,
P.
Artal.
Laboratorio de Optica , Universidad de
Murcia , Murcia , Spain
Exhibit/Poster Hall SA B0169-B0207
Thursday, May 08, 2014 12:00 PM-1:45 PM
Immunology/Microbiology
Moderator: Patrick M. Stuart
6250 — B0169 Demodex and its Association with Chalazia: A Histopathologic Study.
Matthew
J. Schear
Udell 3
1 , T. Milman
, A. Steiner 3 .
1
2 , T. Steiner
Medicine, Glen Cove, NY; 2
3 , C. Shih 3 , I. J.
NYIT College of Osteopathic
Ophthalmology,
New York Eye and Ear Infirmary, Manhatten,
NY; 3 Ophthalmology, Hofstra North Shore-Long
Island Jewish School of Medicine, Great Neck, NY
6251 — B0170 HSV-1 Us9-30 Mutant as a
Candidate HSV Vaccine in a Mouse Ocular
Model.
Matilda F.
Chan
A. Casbon 2 , J. H. LaVail
1 , J. H. Lin
1, 2 .
1
1 , J. M. Draper 1, 2
Ophthalmology, Univ of California-San Francisco, San Francisco, CA;
2 Anatomy, Univ of California-San Francisco, San
Francisco, CA
,
6252 — B0171 Effect of essential oils on the survival rate of Demodex spp.
Maciej K.
Oseka 1 , A. Sedzikowska 2
Poland; 2
. 1 Ofta Spzoo, Warsaw,
Department of General BIology and
Parasitology, Medical University of Warsaw,
Warsaw, Poland *CR
6253 — B0172 Identifying a Host Factor as a New Mediator of Ocular Herpes
Infection.
Satvik Hadigal 1
Shukla 1, 2 .
1
, T. Antoine 1, 2 , D.
Ophthalmology and Visual Sciences,
University of Illinois Chicago, Chicago,
IL; 2 Microbiology and Immunology, University of
Illinois Chicago, Chicago, IL
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
406

Thursday – Posters – 6254 – 6275
6254 — B0173 Outer Membrane Vesicle shedding by P. aeruginosa is Induced by Tear
Fluid or Lysozyme and Compromises Corneal
Epithelial Defenses Against Bacterial Adhesion and Traversal.
Matteo M.
Metrucci o 1
Evans 1, 2 , M. M. Gabriel 3
M. Fleiszig 1, 4 . 1 of California, Berkeley, Berkeley, CA;
, D. J.
, J. Kadurugamuwa
2
3 , S.
School of Optometry, University
College of
3
Pharmacy, Touro University California, Vallejo, CA;
Alcon Laboratories, Fort Worth, TX; 4 University of California, Berkeley, Graduate Groups in Vision
Science, Microbiology, and Infectious Disease &
Immunity, Berkeley, CA *CR
6255 — B0174 Identification of Herpes Simplex
Virus Glycoprotein B Human Epitopes That
Preferentially Recall Polyfunctional CD8+
T Cells from Seropositive Asymptomatic
Individuals and Protect HLA Transgenic Mice
Against Ocular Herpes.
Anthony B.
Nesburn,
A.
Khan , R.
Srivastava , S.
L.
Wechsler1, L.
BenMohamed . Gavin Herbert Eye Institute,
University of California , Irvine , Irvine , CA
6256 — B0175 Role of Dendritic Cells in
Corneal Epithelial Defense against Pseudomonas aeruginosa Colonization and Traversal in Vivo.
David J.
Evan s 1, 2 , C. Tam 2
Fleiszig 2 . 1
, M. M. Metruccio 2 , S. M.
College of Pharmacy, Touro University
California, Vallejo, CA; 2 School of Optometry,
University of California, Berkeley, CA
6257 — B0176 Non-Thermal Dielectric Barrier
Discharge (DBD) Plasma Suppresses Herpes
Simplex Virus Type 1 (HSV-1) Replication in
Corneal Epithelium.
Jane Azizkhan Clifford , O.
Alekseev , K.
Donovan, V.
Limonnik . Biochemistry and Molecular Biology, Drexel University College of Medicine , Philadelphia , PA *CR
6258 — B0177 Epithelium-expressed CXCL10 and Natural killer cells in protective corneal mucosal immunity against Candida albicans infection.
Bing Xu . Anatomy & Cell Biology and Department of Ophthalmology, Wayne State
University School of Medicine , Detroit, MI
6259 — B0178 Pseudomonas aeruginosa
Biofilm (BF) Adhesion and Dispersion on lenses under Ketorolac (KL) and Bromfenac (BR) influence.
Marisa Arcos 1, 2 , A. E. Farinati 1 , M. T.
Diluca 2 , M. G. Santalucia
Buenos Aires, Argentina;
1
2
.
1 Salvador University,
Ophthalmology, Pedro
Fiorito Hospital, Avellaneda, Argentina
6260 — B0179 Ecological Diversity of
Acanthamoeba and Associated Microbial
Communities.
Darlene Miller , M.
Diaz , E.
Perez,
J.
Maestre, E.
C.
Alfonso.
Bascom Palmer Eye
Institute, Univ of Miami Miller Sch of Med, Miami,
FL
6261 — B0180 Investigating Unique DNA
Sequences of L. albertoi from Ocular Disease for Diagnostic Purposes.
Luiza R. Vilela
Vilela 2, 6 , P. R. Vilela
R. R. Sayegh 4
3, 1 , R. C. Vilela 3, 1
, A. L. Mendoza 6
1, 3 , R. R.
, A. Oliveira 5
Horizonte, Brazil; 2
.
1 Ophthalmology,
Centro Oftalmologico de Minas Gerais, Belo
,
Universidade Federal de Minas
Gerais, Belo Horizonte, Brazil; 3 Instituto Superior de Medicina, Belo Horizonte, Brazil; 4 Department of Ophthalmology and Visual Sciences, University
Hospitals Eye Institute Case Western Reserve
University School of Medicine, Cleveland,
OH; 5 Faculdade Ciencias Medicas de Minas Gerais,
Belo Horizonte, Brazil; 6 Biomedical Laboratory
Diagnotisc, Michigan State University, Lansing, MI
6262 — B0181 Immune Factor Levels and
CMV DNA load in Aqueous Humor of CMV
Retinitis - The CRIGSS Study.
Jayant V. Iyer 1, 3 ,
J. Connolly 2
Bernett 2
2 , R. V. Agrawal
, S. C. Teoh 1
1 , T. Yeo 1 , B. Au
.
1 Ophthalmology, Tan Tock
Seng Hospital, Singapore, Singapore;
, L.
2 Singapore
Immunology Network, A*STAR, Singapore,
Singapore; 3 Ophthalmology, Singapore National
Eye Centre, Singapore, Singapore f
6263 — B0182 Defining a new role for cytoskeletal alterations in corneal herpetic disease.
Deepak Shukla , T.
Antoine, V.
Tiwari .
Ophthal/Visual Sciences , University of Illinois at
Chicago, Chicago, IL
6264 — B0183 Cornea transcriptome changes induced by Atmospheric-Pressure Cold
Plasma for the treatment of ocular surface infections.
Andrea Leonardi 1 , E. Tarricone 2, 1 ,
U. Rosani 3 , M. Zuin 4 , E. Martines 4 , P. Venier 3 , P.
.
1 Neuroscience, Ophthalmology, University Brun 2 of Padova, Padova, Italy;
Padua, Italy; 3
2 Histology, Microbiology and Medical Biotechnology, University of Padua,
Italy; 4
Biology, University of Padua, Padua,
Consorzio RFX, Euratom-ENEA Association,
Padua, Italy
6265 — B0184 Susceptibility of C57BL/6 and
Balb/c mice to Vaccinia virus keratitis.
Curtis R.
Brandt , I.
V.
Larsen , H.
Clausius . Ophthal & Visual
Sci, Univ of Wisconsin-Madison, Madison, WI
6266 — B0185 Antimicrobial Peptides and Acanthamoeba: Peptide expression and anti-amoebicidal activity via timelapse imaging.
Joseph C.
Manarang 1 , H.
Baidouri 1 , S. N. Kolar 1 , M. L. Mangoni 2
McDermott 1 . 1 of Houston, Houston, TX;
Rome, Rome, Italy
2
, A. M.
College of Optometry, University
Sapienza University of
6267 — B0186 Structural Insights into
Bactericidal Activity of Corneal Epithelial
Keratin-Derived Antimicrobial Peptides
(KDAMPs).
Tsz Ying (Judy) Lee
1
1, 2 , P. Too 1, 2 , C.
Tam 1, 2 .
Ophthalmic Research, Cleveland Clinic
Lerner Research Institute, Cleveland, OH;
Berkeley, CA *CR
2 School of Optometry, University of California Berkeley,
6268 — B0187 Descemet’s membrane-schisis in fungal keratitis: a pathological analysis of
23 corneal buttons.
Ziyuan Liu, P.
Zhang, C.
Liu, W.
Zhang, J.
Hong , W.
Wang . Department of
Ophthalmology, Peking University Third Hospital ,
Beijing, China
6269 — B0188 Cytotoxicity to Corneal Cells in vitro by Serratia marcescens is Mediated by Transcription Factors FlhC and FlhD and
Requires the ShlA Hemolysin.
Robert M.
Shanks ,
N.
A.
Stella , K.
Brothers , E.
G.
Romanowski .
Ophthalmology, University of Pittsburgh ,
Pittsburgh , PA
6270 — B0189 Esc1-21 a Novel Antimicrobial
Peptide for Microbial Keratitis.
Satya Sree N.
Kola r 1 , H. Baidouri 1 , V. Luca 2 , G. Mannino 2 , M.
L. Mangoni 2 , A. M. McDermott 1 .
1 University of
Houston College of Optometery, Friendswood, TX;
2 Sapienza University of Rome, Rome, Italy
6271 — B0190 Immunofluorescent
Antibody Detection of Enterovirus-specific
Immunoglobulins in Tear and Sera Post
Coxsackievirus A24 Acute Hemorrhagic
Conjunctivitis.
Marlyn P. Langford, M. Burch, D.
E. Texada. Ophthalmology, Lousiana State Univ
Hlth Sci Ctr, Shreveport, LA
6272 — B0191 Neutrophil Transdifferentiation as a Factor of Disease Pathogenesis.
Elizabeth
A.
Berger 1, 2 , C. R. McWhirter 1 , S. A. McClellan 1 ,
L. D. Hazlett 1 , N. Wolf 1 .
1 Anatomy & Cell Biology,
Wayne State Univ Sch of Med, Detroit, MI;
2 Ophthalmology, Kresge Eye Institute, Detroit, MI
6273 — B0192 Riboflavin/UVA-mediated
Elimination of Pathogenic Bacteria with and without Antibiotic Resistance Using an In Vitro
Model of Keratitis Treatment.
K. Makdoumi 2, 3 . 1
Anders Backman 1 ,
Clinical Research Centre, Örebro
University Hospital, Örebro, Sweden; 2 Department of Ophthalmology, Örebro University Hospital,
Örebro, Sweden; 3 Centre for Health Care Sciences,
Örebro University Hospital, Örebro, Sweden
6274 — B0193 Distribution traits of neutrophil in normal cornea in C57BL/6J, BALB/c and nude mice.
Hongmin Zhang, S.
Liu, G.
Chen , H.
Liu, S.
He, L. Wang. Henan Eye Institute, Henan
Eye Hospital, Zhengzhou, China
6275 — B0194 Primary human corneal fibroblasts release specific matrix metalloproteinases in response to live
Pseudomonas aeruginosa infection in-vitro.
Ahmad Elsahn
P. Hossain 1, 2 .
1
1, 2 , P. Rodas 3, 1 , M. Christodoulides 1 ,
Molecular Microbiology, University
2 of Southampton, Southampton, United Kingdom;
Eye Unit, University Hospital Southampton
NHS Foundation Trust, Southampton, United
Kingdom; 3 Medicine and Innovative Science
(CIMIS), Facultad de Medicina, Andres Bello
University, Santiago, Chile f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
407

Thursday Posters 12:00 pm – 1:45 pm
6276 – 6297 – Thursday – Posters
6276 — B0195 Potential autocrine regulation of interleukin-33/ST2 signaling of corneal epithelium in Fungal Keratitis.
Jing Lin, G.
Zhao , L.
Hu , C.
Che, N.
Jiang.
Ophthalmology, the Affiliated Hospital of Qingdao Medical
College,Qingdao University, Qingdao, China
1
6277 — B0196 Inhibition of Corneal
Inflammation by the Lipid Mediator of
Resolvin. Ji-Eun Lee 1, 2 , Y. Sun
Ophthalmology, Pusan National University,
Yangsan, Republic of Korea; 2
2 , E. Pearlman 2 .
Ophthalmology, Case
Western Reserve University, Cleveland, OH
6278 — B0197 Protease-Activated Receptor
(PAR)2, But not PAR1, is Upregulated by Acanthamoeba Plasminogen Activator (aPA) and Induces Proinflammatory Cytokines in
Human Corneal Epithelial Cells.
Trivendra
Tripathi , M.
Abdi , H.
Alizadeh . Cell Biology and
Immunology , Univ of North Texas Hlth Science Ctr,
Fort Worth, TX
6279 — B0198 Role of Pyoverdin in
Pseudomonas aeruginosa Keratitis.
Sayuri
Okamoto
Gotoh 2
1 , N. Oka 1
, Y. Ohashi 1 .
, T. Suzuki
1
1 , N. Hayashi 2 , N.
Ehime University School of
Medicine, Toon, Japan;
University, Kyoto, Japan
2 Kyoto Pharmaceutical
6280 — B0199 Association of HTLV-1 uveitis with systemic inflammatory diseases and adult
T cell leukemia.
Koju Kamo i 1, 2 , Y. Terada 1, 3 ,
K. Miyata 3 , M. Mochizuki 1, 3 .
1 Ophthalmology,
Tokyo Medical and Dental University, Tokyo,
Japan; 2 Research Hospital, The Institute of
Medical Science, The University of Tokyo, Tokyo,
Japan; 3 Miyata Eye Hospital, Miyakonojo, Japan
6281 — B0200 Antibiotic Resistance Profile of Ocular Pathogens - An Update from the
2013 US ARMOR Surveillance Study.
Christine
M. Sanfilippo 1 , T. W. Morris 1 , J. Deane
Draghi
NY; 2
2 , D. F. Sahm 2 .
1
2 , D. C.
Bausch & Lomb, Rochester,
Eurofins Medinet, Chantilly, VA *CR
6282 — B0201 Development of a rapid immunochromatographic test kit using fluorescent silica nanoparticle for detection of Acanthamoeba.
Koji Toriyama 1 , T. Suzuki 1 ,
T. Inoue 1 , H. Eguchi 2 , S. Hoshi 3 , H. Aizawa 4 ,
K. Miyoshi 4 , M. Ohkubo 4 , Y. Ohashi 1 .
1 Ehime
University School of Medicine, Toon, Japan; 2 The
University of Tokushima Graduate School,
Tokushima, Japan; 3 Fujieda Municipal General
Hospital, Fujieda, Japan; 4 Furukawa Electric Co.,
Ltd., Tokyo, Japan *CR
6283 — B0202 Efficacy of photodynamic antimicrobial chemotherapy against herpes simplex virus-type 1.
Taiichiro Chikama 1
1 , T. Sakaguchi
, A.
2 , M. Latief
A. Obana 3
1 , J. Ko
.
1
1 , Y. Kiuchi
Ophthalmology and Visual
Science, Hiroshima University Institute of
Biomedical and Health Sciences, Hiroshima,
Japan; 2 Virology, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima,
Japan; 3 Ophthalmology, Seirei Hamamatsu General
Hospital, Hamamatsu, Japan
6284 — B0203 The role of IL-17 in resistance to Pseudomonas aeruginosa infection.
Cui Li , S.
A.
McClellan, R.
P.
Barrett, L.
D.
Hazlett.
Anatomy and Cell Biology, Wayne State University , Detroit,
MI
6285 — B0204 Identification of miRNAs associated with herpes simplex keratitis by miRNA microarray analysis.
Fei Wang , T.
Qian , X.
Cui, J.
Xu . Eye & ENT hospital , Fudan
University , Shanghai , China
6286 — B0205 Tacrolimus (FK506) suppresses
TREM-1 Expression in a murine model of
Fungal Keratitis.
Jin Yuan , L.
Huang, J.
Zhong.
Zhongshan Opthalmic Center , Guangzhou,
China *CR
6287 — B0206 Torque Teno Virus Revealed by Deep DNA Sequencing of Ocular Surface
DNA.
2
Russell Van Gelder
Shestopalov 3
1 , N. Ko 1
, E. Linardopoulou 1
Ophthalmology, Moorefields Eye Hospital,
London, United Kingdom; 3
, A. Y. Lee
.
1
Ophthalmology, University of Washington, Seattle,
WA;
Ophthalmology,
Bascom Palmer Eye Institute, Miami, FL *CR
2 , V.
Department of
6288 — B0207 Experimental approaches in the analysis of microbial community in ocular samples.
Nabeel M.
Shalab i 1, 2 ,
A. I. Tuzhikov 1 , A. Galor 1, 3 , Q. Dong 4 , A. U.
Panchin 5 , O. Thanathanee 6 , R. Van Gelder 7 , T.
P. O’Brien 1 , V. Shestopalov 1, 8 . 1 Department of
Ophthalmology, Bascom Palmer Eye Institute,
Miami, FL; 2 Department of Ophthalmology, Hail
University, Hail, Saudi Arabia; 3 Department of
Ophthalmology, VA Medical Center, Miami,
FL; 4 Department of Biological Sciences,
University of North Texas, Texas, TX; 5 Institute for Information Transmission Problems, Moscow,
Russian Federation; 6 Department of Ophthalmology,
Srinagarind Hospital Khon Kaen University, Khon
Kaen, Thailand; 7 Department of Ophthalmology,
University of Washington, Seattle, WA; 8 Vavilov
Institute of General Genetics, Vavilov Institute of
General Genetics, Moscow, Russian Federation
Exhibit/Poster Hall SA B0240-B0259
Thursday, May 08, 2014 12:00 PM-1:45 PM
Physiology/Pharmacology
Moderator: Maurizio G. Uva
6289 — B0240 Efficacy of trans-epithelial cross-linking for treatment of progressive keratoconus in paediatric age.
Maurizio G.
Uva, A.
Longo, C.
Rapisarsa, A.
Cantavenera,
M.
Fallico, M.
Reibaldi , E.
Bonacci, T.
Avitabile.
Institute of Ophthalmology, University of Catania,
Catania, Ital y
6290 — B0241 Topical Tacrolimus in Thygeson
Superficial Punctate Keratitis.
Maria Carolina
Marquezan da Silva, H. M. Nascimento, L.
Vieira, M. Serapião, R. Belfort, Jr., D. de Freitas.
UNIFESP, São Paulo, Brazil
6291 — B0242 Outcomes of Ganciclovir
0.15% Ointment use in patients with
Cytomegalovirus(CMV)-related anterior uveitis.
John Wong , S.
C.
Teoh . Ophthalmology,
National Healthcare Group Eye Institute, Tan Tock
Seng Hospital , Singapore, Singapor e
6292 — B0243 Growth factor and interleukin concentrations in amniotic membrane suspension
(AMS).
Berthold Seitz 1, 2 , M. Bischoff 1, 2 , T.
Stachon 1 , M. Huber 2 , M. Zawada 2 , M. Eichler 2 ,
A. Langenbucher 3 , N. Szentmary 1 .
1 Department of Ophthalmology, Saarland University Medical
Center, Homburg/Saar, Germany; 2 LIONS
Cornea Bank Saar-Lor-Lux, Trier/Westpfalz at the Department of Ophthalmology, Saarland
University Medical Center, Homburg/Saar,
Germany; 3 Experimental Ophthalmology, Saarland
University, Homburg/Saar, Germany
6293 — B0244 Inhibition of corneal inflammation by Sulfasalazine-Hyaluronic acid compound in rat alkali burn model.
Choun-
Ki Joo 1, 2 , J. Choi 1 .
1
Republic of Korea; 2
Catholic Institutes of Visual
Science, Catholic Univ Korea Coll of Med, Seoul,
Republic of Korea
Seoul St. Mary’s hospital Eye
Institute, The Catholic University of Korea, Seoul,
6294 — B0245 Immune-Mediated Keratitis in Dogs Following Treatment with Topical
Carbonic-Anhydrase Inhibitors.
Billie
Beckwith-Cohen 1 , E. Bentley 2 , D. J. Gasper 1 , R. R.
Dubielzig 1 .
1 Pathobiological Sciences, University of Wisconsin- Madison, Madison, WI; 2 Surgical
Sciences, University of Wisconsin- Madison,
Madison, WI
6295 — B0246 Suppression of ocular inflammation by a combination of renin inhibitor and prorenin receptor blocker.
Qiuhong Li 1
K. Shil 1 , A. Verma
Batenburg 2 . 1
1
Ophthalmology, University of Florida,
Gainesville, FL; 2
, P. Zhu 1 , J. A. Danser 2
, P.
, W. W.
Internal Medicine, Erasmus MC,
Rotterdam, Netherlands
6296 — B0247 Inhibition of Experimental
Autoimmune Anterior Uveitis by Chitosan
Oligosaccharides.
Sheng-Li Ch o 1 , C. Yang 2 , I.
Fang 3 . 1 School of Medicine, National Taiwan
University, Taipei, Taiwan; 2 Department of
Ophthalmology, National Taiwan University
Hospital, Taipei, Taiwan; 3 Department of
Ophthalmology, Taipei City Hospital Zhongxiao
Branch, Taipei, Taiwan
6297 — B0248 Anti-inflammatory effects of the glucocorticoid loteprednol etabonate in human ocular and inflammatory cells.
Thomas
R.
Vollmer, M.
E.
Cavet, K.
L.
Harrington , S.
M.
Volhejn, M.
Richardson . Preclinical Pharmacology ,
Bausch + Lomb , Rochester, NY *CR
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
408

Thursday – Posters – 6298 – 6315
6298 — B0249 Bivalent anti-TNF-α Fab-PEG-
Fab for ocular inflammation.
Hanieh Khalili 1, 2 , A.
Khalili 2 , G. Sharma 1, 2 , A. Lockwood 1, 2 , P. Khaw 2 ,
S. Brocchini 1, 2 .
1 UCL School of Pharmacy, London,
United Kingdom; 2 National Institute for Health
Research (NIHR) Biomedical Research Centre at
Moorfields Eye Hospital NHS Foundation Trust and
UCL Institute of Ophthalmology, London, United
Kingdom
6299 — B0250 Immunosuppressive treatment in Sympathetic ophthalmia: long-term visual outcome.
Hrarat Linda, C.
Fardeau.
hopital pitie salpetriere, Stains, France
6300 — B0251 A new artificial tear testing in
New Zeland Rabbits.
Yussett Contreras, O.
Olvera ,
P.
A.
Marquez, L.
M.
Baiza-Duran, P.
Melgarejo, J.
Bonilla, G.
Fregoso.
Medical Research Department ,
Laboratorios Sophia SA de CV , Zapopan,
Mexico *CR
6301 — B0252 Treatment of dry eye in live rabbit model using a novel hyaluronic acid and sulphonamide topical drop.
Ben B. Muirhead, V.
Gupta, H. Sheardown. Biomedical Engineering,
McMaster University, Elmira, ON, Canada
6302 — B0253 Improved Staining, Tear Film
Breakup Time, and Dry Eye Severity Level
Following a Six-Month Treatment of a Cohort of
Dry Eye Patients in Norway.
Jon Roger Eide t 1, 2 ,
T. P. Utheim 1, 2 , . A. Utheim 1, 2 , X. Chen 2, 3 , A.
Stojanovic 3, 4 , S. Ræder 2, 3 . 1 Department of Medical
Biochemistry, Oslo University Hospital, Oslo,
Norway; 2 The Norwegian Dry Eye Clinic, Oslo,
Norway; 3 SynsLaser Kirurgi, Tromsø and Oslo,
Norway; 4 Department of Ophthalmology, University
Hospital of North Norway, Tromsø, Norway *CR
6303 — B0254 Dysfunction of Rab3D Is
Associated with Increased Secretion of Tear
Cathepsin S, a Tear Biomarker of Sjögren’s
Syndrome.
Zhen Meng , M.
Edman-Woolcott , C.
Ding , S.
F.
Hamm Alvarez.
Pharmacology and
Pharmaceutical Sciences , School of Pharmacy ,
University of Southern California , Los Angeles, CA
6304 — B0255 Evaluation of Demoxoft
Lipogel and Demoxoft Liquid efficacy and safety in patients with Demodex blepharitis.
Malgorzata Krajewska 1 , J. Wasyluk 1,
5 , M. K. Oseka 3 , A. Sedzikowska 2 , B. Roman 4 , E.
Jaremko 4 .
1 Ophthalmological Center Optimum,
Warsaw, Poland; 2 Department of General BIology and Parasitology, Medical University of Warsaw,
Warsaw, Poland; 3 Ofta Sp. z o.o., Warsaw,
Poland; 4 Verco Sp. z o.o., Warsaw, Poland; 5 Eye
Clinic, Military Institute of Avation Medicine,
Warsaw, Poland *CR
6305 — B0256 The Effect of Teprotumumab
(RV001) IGF-1 Receptor Blocking Antibody on Hematopoietic Cell Function: Implications for Graves’ Orbitopathy.
Denise S. Kim 1 , T. J.
Smith 1, 2 , T. Mester 1 , R. S. Douglas 1, 3 .
1 Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Kellogg Eye Center,
Ann Arbor, MI; 2 Department of Internal Medicine,
Division of Metabolism, Endocrinology, and
Diabetes, University of Michigan Medical School,
Ann Arbor, MI; 3 Ann Arbor Veterans Administration
Medical Center, Ann Arbor, MI *CR
6306 — B0257 Profiling expression of NF-κB signaling target genes in IKK-2 inhibitor treated pterygium and conjunctiva fibroblast cells.
Aihua
Hou 1 , M. Tin 1 , L. Tong 1, 2 . 1 Singapore Eye Research
Institute, Singapore, Singapore; 2
Eye Center, Singapore, Singapore
Singapore National
6307 — B0258 Cytokines in corneal washes as prognostic indicators of recurrent pterygium.
Tine Possemiers , E.
Vandeweyer ,
V.
De Groot, M.
B.
Tassignon, N.
Zakaria.
Ophthalmology, University Hospital Antwerp,
Edegem , Belgium
6308 — B0259 Evaluation of Pirfenidone as a Postoperative Anti-proliferative Agent in Experimental Cataract Surgery: A Pilot
Study.
Yangfan Yang, X. Lin, K. Wu, M. Yu.
Zhongshan Ophthalmic Center, Sun Yat-sen
University, Guangzhou, China
Exhibit/Poster Hall SA B0260-B0295
Thursday, May 08, 2014 12:00 PM-1:45 PM
Retinal Cell Biology
Moderator: Vera L. Bonilha
6309 — B0260 The apical polarity of Na+,K+-
ATPase in ARPE-19 cells is regulated by the expression of the β2 subunit.
Jorge Alberto
Lobato 1 , A. Loza-Huerta 1
R. Gonzalez 2 , L. Shoshani
, J. Bonilla-Delgado 3
1 . 1 Physiology,
CINVESTAV-IPN, Mexico City, Mexico;
,
Biology, CINVESTAV-IPN, Mexico City,
Mexico; 3 Genetic and molecular diagnosis, Unidad de Investigación Hospital Juárez de Mexico,
Mexico City, Mexico
2 Cell
6310 — B0261 In pursuit of authenticity:
Comprehensive analysis of iPSC derived RPE offer a benchmark and insight for clinical applications.
Qin Wan 1 , K. J. Miyagishima 1 , M. R.
Lotfi 1 , A. Maminishkis
F. Hua 1 , S. Temple
NIH, Bethesda, MD;
Rensselaer, NY
2
2
1 , R. Sharma 1
, S. S. Miller
, B. Corneo
1 , K. Bharti 1 .
1
2 ,
NEI/
Neural Stem Cell Institute,
6311 — B0262 Transgenic Mouse Models of Marfan Syndrome (Fibrillin-1) Exhibit
Elongated Ocular Axial Length.
Aakriti Garg 1 ,
E. D. Gavazi 1 , W. Lee 1, 2
, E. E. Flynn 2
, Q. V. Hoang
, H. O. Lloyd 1
1 , R. H.
, S. H. Silverman 1
Tsang 1, 2 . 1 Department of Ophthalmology, Columbia
University College of Physicians and Surgeons,
New York, NY; 2 Pathology & Cell Biology,
Columbia University College of Physicians and
Surgeons, New York, NY
6312 — B0263 Fluid transport defects in a mouse model of X-linked juvenile retinoschisis
(XLRS).
Yingxiang Huang, H.
Xia, J.
D.
Ash.
Ophthalmology, University of Florida, Gainesville,
FL
6313 — B0264 Evaluation of LED lighting ocular toxicity.
Picard 1, 2
Cohen 1, 3
Arthur
, M. Berdugo 1, 2
Krigel
, L. Jonet 1, 2
, C. Andrieu-Soler 1, 2 .
1
1, 2 , L. Bessalah 1, 2 team17, INSERM, Paris, France;
, E.
, F. F. Behar-
CRC UMRS872
5 Paris 6, Paris, France; 3
2 Universirté Paris
Université de Lausanne,
Hospital Jules Gonin, Lausanne, Switzerland
6314 — B0265 An organotypic culture model of porcine neuroretina supplemented with porcine retinal pigment epithelium (pRPE) cells to simulate an ex vivo subretinal space.
Salvatore Di Lauro 1, 2 , I. Fernandez-Bueno 1, 3 , D.
Rodríguez-Crespo 1 , G. K. Srivastava 1, 3 , A. K.
Singh 1 , M. Garcia-Gutierrez 1, 3 , M. Gayoso 4 , J.
Pastor 1, 2 . 1 Ophthalmology, Instituto Universitario de Oftalmobiologia Aplicada (IOBA), University of Valladolid, Valladolid, Spain; 2 Ophthalmology,
Hospital Clinico Universitario de Valladolid,
University of Valladolid, Valladolid, Spain; 3 CIBER de Bioingenieria, Biomateriales y Nanomedicina
(CIBER-BBN), Valladolid, Spain; 4 Cellular
Biology, Histology and Pharmacology, University of Valladolid, Valladolid, Spain
6315 — B0266 The Mouse Homolog of the
Human LCA3 Gene, Spata7, Plays a Critical
Role in Cilium Structural Maintenance and
Protein Trafficking in Photoreceptor Cells.
Rui
Chen 1, 2 , A. Eblimit
Esteve-Rudd
R. Roepman 3
4
1, 2 , Y. Chen
, L. Gan
, G. Mardon . 1
1, 2
5 , S. M. Wu
2
, M. Nguyen 3
6
, J.
, D. S. Williams
Genetics, Baylor College of Medicine, Houston,
TX; 2 Human Genome Sequencing Center, Baylor
College of Medicine, Houston, TX; 3
4
Molecular and Human
,
Dept. of
Human Genetics, Radboud University Medical
Center, Nijmegen, Netherlands; 4 Jules Stein Eye
Institute, UCLA, Los Angeles, CA; 5 Department of
Ophthalmology, University of Rochester, Rochester,
NY; 6 Department of Ophthalmology, Baylor College of Medicine, Houston, TX f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
409

Thursday Posters 12:00 pm – 1:45 pm
6316 – 6335 – Thursday – Posters
6316 — B0267 Correlation between OCT measurement of the retinal nerve fibre layer thickness and RGC loss after optic nerve section in the adult rat.
Francisco M. Nadal-
Nicolas 1 , G. Rovere
Nieto-Lopez 1
Villegas-Perez 3
2 , P. Sobrado-Calvo
, C. Nucci 2 , M. Agudo
, M. Vidal-Sanz 3 .
1
1
3 , L.
, M. P.
Ophthalmology,
Instituto Murciano de Investigación Biosanitaria-
Hospital Clínico Universitario Virgen de la
Arrixaca (IMIB), 30120 Murcia, Spain, Murcia,
Spain; 2 Ophthalmology Unit, Department of Exp
Medicine and Surgery, University of Rome Tor
Vergata, Rome, Italy; 3 Ophtalmology, Departamento de Oftalmología, Facultad de Medicina, Instituto
Murciano de Investigación Biosanitaria (IMIB),
Campus Espinardo, 30.100 Murcia, Spain, Murcia,
Spain
6317 — B0268 Ablation Of Raf-1 Kinase
Inhibitory Protein (RKIP) Improves
Photoreceptor Structure and Function in a
Cep290-Mutant Mouse Model Of Severe Retinal
Degeneration.
Balajikarthick Subramanian, M.
Anand, H.
Khanna . Ophthalmology, University of
Massachusetts, Worcester, MA
6318 — B0269 The Mitochondrial Complex
I Inhibitor, Rotenone, Induces Endoplasmic
Reticulum Stress and Activation of GSK-3β in Cultured Rat Retinal Cells.
Guoge Han, R.
Casson , J.
P.
Wood , G.
Chidlow.
Ophthalmology,
Hanson Institute, Adelaide , SA , Australia
6319 — B0270 Oxidative Stress Modulates
Glutathione S-Transferase Pi Isoform
(GSTP1) Expression in Human Retinal
Pigment Epithelial Cells.
Matthew Donovan 1 ,
A. M. Saeed
W. Lee 3
1 , M. Hyska 2
2
, M. Marin-Castano 3 ,
.
1 University of Miami Miller School of
Medicine, Miami, FL; Michigan State University
College of Osteopathic Medicine, East Lansing,
MI; 3 Ophthalmology, Bascolm Palmer Eye Institute-
University of Miami, Miami, FL
6320 — B0271 Pan-retinal, subretinal aggregates in Macular Telangiectasia Type
2.
Michael B. Powner 1 , M. C. Gillies 2
P. S. Bernstein
M. Fruttiger 1 .
1
3 , G. S. Hageman 3
, M. Zhu
, C. A. Egan 4
Ophthalmology, London, United Kingdom;
Sight Institute, University of Sydney, Sydney,
NSW, Australia; 3
2 ,
Cell Biology, UCL Institute of
,
2 Save
Department of Ophthalmology
& Visual Sciences, University of Utah, Salt Lake
City, UT; 4 Medical Retina, Moorfields Eye Hospital,
London, United Kingdom *CR
6321 — B0272 Cefuroxime toxicity in human retinal pigment epithelial cells - Implications for preventing or treating endophthalmitis in vitreoretinal surgeries.
Yi Sheng Chang.
1 Department of Ophthalmology, National Cheng
2
Kung University, Taiwan, Tainan City, Taiwan;
Department of Ophthalmology, National Cheng
Kung University Hospital, Taiwan, Tainan City,
Taiwan
6322 — B0273 CYP2E1 mediated ethanol metabolism in ARPE-19 cells.
Natalia Martínez ,
S.
Atienzar , M.
Flores Bellver, L.
Bonet, J.
Sancho -
Pelluz , J.
M.
Barcia , F.
J.
Romero . Phisiology ,
Universidad Católica de Valencia , Valencia , Spain
6323 — B0274 Delayed Administration of Bone
Marrow Mesenchymal Stem Cell Conditioned
Media Significantly Improves Outcome after
Retinal Ischemia in Rats.
Steven Roth 1 , J.
Dreixler 1 , J. N. Poston 2 , I. Balyasnikova 3 , A. R.
Shaikh 1 , K. Y. Tupper 1 , S. M. Conway 1 , M. M.
Marcet 3 , M. S. Lesniak 3 . 1 Anesthesia and Critical
Care, Univ of Chicago, Chicago, IL; 2 Pritzker
School of Medicine, Univ of Chicago, Chicago,
IL; 3 Surgery, Univ of Chicago, Chicago, IL
6324 — B0275 Is There a Relationship
Between Extranuclear DNA and Degenerative
Mitochondria?.
Alexander Ogilvy 1
, M. S. Abu-Asab 1 .
1
, D. Shen
Chan 1, 2
National Eye Institute, Bethesda, MD; 2
2 , C.
Histopathology Core,
Laboratory of Immunology, National Eye Institute, Bethesda,
MD
6325 — B0276 Influence of sigma receptor-1
(σR1) on inflammatory, stress and toxicity mediators in retinal Müller glia (rMG).
Arul
Shanmugam 1, 2 , S. Markand 1, 2 , A. M. Tawfik 1, 2 , E.
Zorrilla 3 , V. Ganapathy 2, 4 , S. B. Smith 1, 2 .
1 Cellular
Biology & Anatomy, Georgia Regents University,
Augusta, GA; 2 James and Jean Culver Vision
Discovery Institute, Georgia Regents University,
Augusta, GA; 3 Neurological Research Institute,
The Scripps Institute, LaJolla, CA; 4 Biochemistry
& Molecular Biology, Georgia Regents University,
Augusta, GA
6326 — B0277 The effects of antivascular endothelial growth factor on cell viability, oxidative stress and mitochondrial bioenergetics.
Chan 3 .
1
Shwu Jiuan Sheu 1, 2 , N. Liu 1 , J.
Ophthalmology, Kaohsiung Veterans
General Hospital, Kaohsiung, Taiwan; 2 National
Yang Ming Univerisity, Taipei, Taiwan; 3 Center for Translational Research in Biomedical Science,
Kaohsiung Chang Gung Memorial Hospital,
Kaohsiung, Taiwan
6327 — B0278 In Situ Localization of
Complement Factor H Gene Expression in the
Mouse Eye.
Sharon L.
Oltjen 1 , L. M. Hjelmeland 1 ,
R. A. Radu 2 . 1 Ophthalmology, University of
California-Davis, Davis, CA; 2 Jules Stein Eye
Institute, Univerisity of California-Los Angeles, Los
Angeles, CA
6328 — B0279 Regulation of TRPV2 channel surface expression in the retinal pigment epithelium.
Reichhart 1 .
1
Olaf Strauss 1 , F. Fried 2 , N.
Experimental Ophthalmology, Charite
University Medicine Berlin, Berlin, Germany; 2
Hospital, University Medicine Regensburg,
Regensburg, Germany
Eye
6329 — B0280 Sustained elevated light exposure in mice leads to strain dependent dysregulation of the complement system in the eye.
Philipp Herrmann 1, 2
, K. M. Nishiguchi 1
, J. Cowing 1 , S. E.
, U. F. Luhmann 1 , Liyanage 1
R. R. Ali 1 .
1 Department of Genetics, UCL,
Institute of Ophthalmology, London, United
Kingdom; 2 Department of Ophthalmology,
University of Bonn, Bonn, Germany
6330 — B0281 Loss of CCL5 Signaling
Induces Visual Dysfunction in Healthy
Retina.
D’Anne S. Duncan 1 , A. C. Rehorn 1 ,
R. M. Sappington
Vanderbilt University Medical Center, Nashville,
TN; 2
1, 2 .
1 Vanderbilt Eye Institute,
Vanderbilt Vision Research Center, Vanderbilt
University Medical Center, Nashville, TN
6331 — B0282 Retinal Histopathology in Eyes from a Patient with Digenic
Usher Syndrome Caused by Mutations in USH2A and GPR98.
Meghan J.
Marino
L. Bonilha
Kimberling
1 , M. E. Rayborn
2 , E. I. Traboulsi
1 . 1
1 , B. A. Bell 1
1
, W. J.
1 , S. A. Hagstrom
, V.
Ophthalmic Research, Cole
1 ,
J. G. Hollyfield
Eye Institute, Cleveland Clinic, Cleveland,
OH; 2 Department of Ophthalmology and Visual
Sciences, University of Iowa, Iowa City, IA
6332 — B0283 Retinal Histopathology in
Eyes from Patients with Best Disease Caused by VMD2 Mutations.
Mary E.
Rayborn 1 , V. L.
Bonilha 1 , B. A. Bell
I. Traboulsi 1
1 , M. J. Marino 1
, C. D. Beight 1
Fishman 2 , J. G. Hollyfield 1
, S. A. Hagstrom 1
. 1
, G. J. Pauer 1
Ophthalmology, Cole
Eye Institute/CCLCM, Cleveland, OH; 2
Are Blind or Visually Impaired, Chicago, IL
, E.
, G. A.
Tangere
Center at The Chicago Lighthouse for People Who
6333 — B0284 A Mutant of RPE65
D477G Affects Subcellular Localization of
Wild-type RPE65 by Formation of Protein
Complexes.
Younghwa Shin 1
P. Moiseyev 1 , Y. Takahashi 2
1 , O. Nikolaeva
, J. Ma 1, 2 . 1
, G.
Physiology,
The University of Oklahoma HSC, Oklahoma City,
OK; 2 Harold Hamm Diabetes Center, Oklahoma
City, OK
6334 — B0285 Activation of Primary Retinal
Pigment Epithelial Cells by Complement
Component C5a.
Susanne Wasmut h 1 , M. Busch 1 ,
A. Lommatzsch 2 , D. Pauleikhoff 2, 3 .
1 Ophthalmology at St. Franziskus Hospital, Ophtha-Lab, Münster,
Germany; 2 Ophthalmology at St. Franziskus
Hospital, Münster, Germany; 3 Ophthalmology of
University Duisburg-Essen, Essen, Germany
6335 — B0286 IL-6 deficiency in the retina and its consequences on the murine visual system.
Franklin
Sappington 2 . 1
Nashville, TN; 2
D.
Echevarria
Vanderbilt Eye Insitute, Vanderbilt
University, Nashville, TN
1, 2 , R. M.
Neuroscience, Vanderbilt University,
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
410

Thursday – Posters – 6336 – 6352
6336 — B0287 Targeted deletion of microRNA-204 in mice impairs structure and visual function of RPE and retina.
Congxiao
Zhan
Maminishkis
MD;
MD
2 g 1 , K. J. Miyagishima
1 , S. S. Miller 1
1 , L. Dong
. 1
2 , A.
Sec of Epi & Retinal
Physiol Diseases, National Eye Institute, Bethesda,
Genetic Engineering Facility, NEI, Bethesda,
6337 — B0288 Gpr91, a pro-angiogenic receptor for succinate, is upregulated in hemojuvelin-null mouse retina via increased
BMP6 signaling.
Pachiappan Arjunan 1, 2
Gnana-Prakasam 1, 2 , S. Ananth
R. Veeranan-Karmegam
Ganapathy 1, 2 . 1
1, 2
, J.
, M. A. Romej
1 , S. B. Smith 3, 2 , V.
1 ,
Department of Biochemistry and
Molecular Biology, Georgia Regents University,
Augusta, GA; 2 Vision Discovery Institute, Georgia
Regents University, Augusta, GA; 3 Department of
Cellular Biology and Anatomy, Georgia Regents
University, Augusta, GA
6338 — B0289 Retinal Histopathology in Eyes from a Carrier of XLRP with an RP2 Mutation.
M. E. Rayborn
Heckenlively 2
1
Gayle J.
, B. A. Bell 1
Paue
, M. J. Marino
, E. I. Traboulsi 1
J. G. Hollyfield 1 r 1 , V. L. Bonilha
, S. A. Hagstrom 1
Cole Eye Institute i-31,
Cleveland Clinic, Cleveland, OH; 2
1 , J. R.
,
1 ,
. 1
Department of
Ophthalmology and Visual Sciences, University of
Michigan, Ann Arbor, MI
6339 — B0290 Characterization of Calcium
Currents in Stem Cell Derived Retinal
Pigment Epithelium.
Uusitalo 2, 3 , H. Skottman
S. Nymark 1, 3 . 1
Iina
2, 3
Vainio 1, 3
Department of Electronics and
Communications Engineering, Tampere University of Technology, Tampere, Finland; 2
, K. M. Juuti-
, J. A. Hyttinen 1, 3 ,
Institute of
Biomedical Technology, University of Tampere,
Tampere, Finland; 3 BioMediTech, Tampere, Finland
6340 — B0291 Regulation of Nucleocytoplasmic
Partitioning and Proteostasis of Substrates and
Chemokine Signaling by Ran-binding protein 2
(Ranbp2) in Thy1 in Cho 1 , S. Qiu
P. A. Ferreira 1
1
+ -Ganglionic Neurons.
Kyoung-
, D. Yoon 1 , M. Yu
.
1
Medical Center, Durham, NC; 2
2 , N. S. Peachey
Ophthalmology, Duke University
Ophthalmic
Research, Cole Eye Institute, Cleveland Clinic
Foundation, Cleveland, OH
2 ,
6341 — B0292 Protective effect of lutein on the light-induced disruption of the cell-cell junction in the retinal pigment epithelium.
Mamoru Kamoshita
Kobayashi
Ozawa 1 .
1
2 , T. Kurihara 1 of Medicine, Shinjyuku, Japan; 2
Co.Ltd, Shimogyo, Japan *CR
1 , S. Miyake
, N. Nagai 1
1, 2
, K. Tsubota
, S.
1 , Y.
Ophthalmology, Keio University School
Wakasa Seikatsu
6342 — B0293 Identification of a Canonical Set of Biomarkers to Obtain Pure Retinal Pigment
Epithelial Cells from Differentiated Induced
Pluripotent Stem Cells.
Andrea Li 1
D. Riordan
R. Gundry 3
Bharti 1
2 , F. Hua 1 , O. Memon 1
, S. S. Miller 1
, V. Khristov 1
, A. Maminishkis
MD;
WI; 4
3
National Institute on Aging, Bethesda,
Medical College of Wisconsin, Milwaukee,
Kong
University of Hong Kong, Pokfulam, Hong
,
.
1
, K. Boheler 4
1 ,
, K.
Unit on Ocular and Stem Cell Translational
Research, National Eye Institute, Bethesda,
MD; 2
6343 — B0294 A critical role for caveolin-1 in eNOS-dependent retinal arterial autoregulation and eNOS-independent retinal venous pathology.
Xiaowu Gu 1, 2 , S. J. Fliesler 3,
4 , Y. Zhao 5 , W. B. Stallcup 6 , A. Cohen 2 , M. H.
Elliott 1, 2 . 1 Oklahoma Center for Neuroscience,
University of Oklahoma Health Sciences
Center, Oklahoma City, OK; 2 Department of
Ophthalmology and Dean McGee Eye Institute,
University of Oklahoma Health Science Center,
Oklahoma City, OK; 3 Research Service,
Veterans Administration Western New York
Healthcare System, Buffalo, NY; 4 Departments of Ophthalmology and Biochemistry, University at Buffalo, and the SUNY Eye Institute, Buffalo,
NY; 5 Department of Pharmacology and Center for Lung and Vascular Biology, University of
Illinois College of Medicine, Chicago, IL; 6 Tumor
Microenvironment Program, Sanford-Burnham
Medical Research Institute, La Jolla, CA
6344 — B0295 TLR3 stimulation leads to ATP release from both RPE cells and optic nerve head astrocytes; a common pathway to escalate the inflammatory response in ocular cells?.
Claire
H.
Mitchell 1, 2 , J. M. Beckel 1
M. Laties 3 . 1 of Pennsylvania, Philadelphia, PA; 2
1 , J. Lim 1 , A.
Anatomy and Cell Biology, University
Physiology,
University of Pennsylvania, Philadelphia,
PA; 3 Ophthalmology, University of Pennsylvania,
Philadelphia, PA
, W. Lu
Exhibit/Poster Hall SA C0122-C0147
Thursday, May 08, 2014 12:00 PM-1:45 PM
Retina
6345 — C0122 Long-term results of laser photocoagulation sparing the papillomacular bundle for peripapillary polypoidal choroidal vasculopathy lesions.
Yukari Shirakata 1
F. Shiraga 2 , C. Shiragami
A. Fujiwara 2 .
1
1 , A. Yamashita
Ophthalmology, Kagawa
,
1 ,
University Faculty of Medicine, Kita-gun,
Japan; 2 Ophthalmology, Okayama University
Faculty of Medicine, Okayama, Japan *CR
6346 — C0123 Photothermal Stimulation of the Macula for Treatment of Chronic Central
Serous Retinopathy.
Palanker 1 .
1 Ophthalmology and HEPL, Stanford
Brazil *CR , f
Daniel Lavinsky
University, Stanford, CA; 2
2, 1 , D. V.
Ophthalmology, Federal
University of Rio Grande do Sul, Porto Alegre,
6347 — C0124 Treatment with a nanosecond laser reduces drusen and thins Bruch’s membrane: evidence from human and animal model studies.
Erica L.
Fletcher 1 , S. A. Mills 1 , K.
Vessey 1 , U. Greferath 1 , C. D. Luu 2 , K. Brassington 2 ,
K. Aung 2 , M. J. Plunkett 3 , R. H. Guymer 2 , A. I.
Jobling 1 . 1 Dept Anatomy/Neuroscience, University of Melbourne, Parkville, VIC, Australia; 2 Centre for Eye Research Australia, The University of
Melbourne, Melbourne, VIC, Australia; 3 Ellex Pty
Ltd, Adelaide, SA, Australia *CR , f
6348 — C0125 Effect of Selective Retina
Therapy (SRT) on the inflammatory microenvironment of the subretinal space.
Jost
Hillenkamp
Brinkmann 2
1 , S. Bartsch
, J. Roider 1 .
1
1
, A. K. Klettner 1 , R.
Ophthalmology, University
Medical Center Schleswig-Holstein, Kiel,
Germany; 2 Medical Laser Center Lübeck, Lübeck,
Germany *CR
6349 — C0126 The Effect Of Macular Laser
On Vitreomacular Adhesion In Patients
Undergoing Treatment For Diabetic Macular
Edema.
Corey Waldman, D.
Ellenberg, P.
H.
Scharper . Ophthalmology, Krieger Eye Istitute ,
Baltimore, MD
6350 — C0127 Accurate Definition of
Photocoagulation Intensity by Optical Coherence
Tomography (OCT), Microperimetry and
Temperature.
Stefan O. Koinzer
K. Purtskhvanidze 1 , J. Heckmann 1
1 , M. J. Saeger
, K. Schlott 2, 3
1
,
,
A. Baade
Roider 1 .
1
3, 2
Ophthalmology, Kiel University, Kiel,
Germany; 2
, A. Caliebe 4 , R. Brinkmann
University, Luebeck, Germany; 3
3, 2 , J.
Institute of Biomedical Optics, Luebeck
Medical Laser
Center Luebeck, Luebeck, Germany; 4 Institute for
Medical Informatics and Statistics, Kiel University,
Kiel, Germany
6351 — C0128 Novel 3-Nanosecond Pulse laser and Diabetic Macular Edema: Changes in Visual Acuity and OCT guided analysis of the FLUID.
Amanpreet Kaur , T.
Chau , N.
Jaross .
Ophthalmology, Vision Eye Institute, Footscray,
VIC, Australia
6352 — C0129 Functional Evaluation Using
Multifocal Electroretinogram after Selective
Retinal Therapy by Microsecond-Pulsed
Laser Equipped with Automated Real-Time
Reflectometry.
Tae Kwann Park 1
Y. Ohn 1 .
1
, H. Kim 1 , J. Han 1 ,
, T. Ha 2 Department of Ophthalmology,
Soonchunhyang University Hospital, Bucheon,
Republic of Korea; 2 R&D Department, Lutronic,
Goyang, Republic of Korea f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
411

Thursday Posters 12:00 pm – 1:45 pm
6353 – 6376 – Thursday – Posters
6353 — C0130 Electroretinographic findings associated with selective retina therapy (SRT) versus conventional panretinal photocoagulation
(PRP) in rabbits.
Young Jung Roh, Y.
Park .
Ophthalmology, Yeouido St Mary › s Hospital ,
Catholic University of Korea, Seoul, Republic of
Korea
6354 — C0131 Barely Visible And
Subthreshold 577NM (Yellow) Pascal ® Laser
With And Without Endpoint Management ®
In Proliferative Diabetic Retinopathy And
Diabetic Macular Oedema.
Maria Gil Martinez 1 ,
S. Pastor 1 , K. Yau 1 , Y. D’Souza 1 , S. Mahmood 1 ,
S. Charles 1 , G. Turner 1 , D. McLeod 1, 2 , D. B.
Henson 1, 2 , P. E. Stanga 1, 2 .
1 Ophthalmology,
Manchester Vision Regeneration (MVR) Lab at NIHR/ Wellcome Trust Manchester CRF and
Manchester Royal Eye Hospital, Manchester,
United Kingdom; 2 Manchester Academic Health
Science Centre and Centre for Ophthalmology and
Vision Research, Institute of Human Development,
University of Manchester, Manchester, United
Kingdom *CR
6355 — C0132 F/A and ICG guided, subthreshold, reduced fluence Focal Laser
Photocoagulation Treatment (SRFLPT) in patients with Diabetic Clinically Significant
Macular Edema (CSME): Two Year results.
Georgios Papastergiou , F.
El Jabali , K.
Waite, M.
Bennett.
Retina Institute of Hawaii ,
Honolulu , HI f
6356 — C0133 Micropulse Laser Therapy For
The Treatment Of Longstanding Refractory
Pseudophakic Cystoid Macular Edema.
Joao
Guilherme Aguirr e 1, 2 , A. J. Dare 2, 3 .
1 Instituto
Reynaldo Rezende, Ribeirao Preto, Brazil; 2 HOIP,
Araraquara, Brazil; 3 CRV, Ribeirao Preto, Brazil
6357 — C0134 Comparing Morbidity Rates in
Retinopathy of Prematurity Treated with Either
Intravitreal Bevacizumab or Conventional Laser
Therapy.
Stephen M.
Huddleston , J.
Calderwood ,
M.
E.
Hoehn.
Ophthalmology, University of
Tennessee, Memphis, TN
6358 — C0135 Adherence to laser therapy in diabetic patients in INDEN, Santo Domingo,
Dominican Republic, from April 2012 to April
2013.
Lyam Ciccone 2, 1 , R. E. Valdez 2, 1 , F. Gomez 1, 2 ,
J. Soria 1 .
1 INDEN, Santo Domingo, Dominican
Republic; 2 UNIBE, Santo Domingo, Dominican
Republic
6359 — C0136 Optical coherence Tomography
(OCT) to evaluate treatment of Diabetic macular edema using intravitreal injection of triamcinolone and argon laser treatment.
soheir
M. Mahmoud Ali. Ophthalmology, Kasr Al Einy hospital Cairo University, Dokki Giza, Egypt f
6360 — C0137 The efficacy and safety of 577-nm subthreshold diode micropulse photocoagulation in macular edema.
Sophia
Wong , E.
Ramenaden, R.
Alhabshan, L.
Smithen,
J.
R.
Mathura.
Ophthalmology, The George
Washington University, Washington, DC
6361 — C0138 Preservation of the
Photoreceptor Layer following Subthreshold
Laser Treatment for Diabetic Macular Edema as
Demonstrated by SD-OCT.
Dafna Goldenberg 1, 2 ,
M. Goldstein
U. Soiberman
1, 2
1, 2
, P. Pianka
. 1
3 , A. Loewenstein
Ophthalmology, Tel Aviv
Medical Center, Tel Aviv, Israel; 2 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv,
Israel; 3 Lumenis Ltd, Yokneam, Israel *CR
1, 2 ,
6362 — C0139 A histological comparison of micropulse and standard laser treatment in threshold and sub-threshold modes.
Amy C.
Lo 1, 2 , V. Chong 3, 1 . 1 , L. Lau 1 , I. Wong 1, 2
Hong Kong, Hong Kong; 2
Department of Ophthalmology, The University of Hong Kong,
Research Center of
Heart, Brain, Hormone and Healthy Aging, The
University of Hong Kong, Hong Kong, Hong
Kong; 3 Oxford Eye Hospital, Oxford University
Hospitals, Oxford, United Kingdom *CR
6363 — C0140 Combination therapy with subthreshold diode laser micropulse photocoagulation and intravitreal anti-vascular endothelial growth factor injections for diabetic macular edema.
Sumeer Thinda , A.
P.
Patel, A.
A.
Hunter , A.
Moshiri, L.
S.
Morse.
Ophthalmology and Vision Science, University of California Davis
Eye Center , Sacramento , CA
6364 — C0141 Subthreshold Micropulse Diode
Laser Photocoagulation (577nm) for Macular
Edema secondary to retinal vein occlusion in
Korean Patients.
Yong Sung You, D.
Lee, S.
Sung ,
H.
Oh , S.
Kim, O.
Kwon . Nune Eye Hospital ,
Seoul, Republic of Korea
6365 — C0142 Laser photocoagulation of peripapillary choroidal neovascular membranes
1
(CNVM).
Suruchi Bhardwaj 1, 2 , T. R. Vrabec 2 .
Ophthalmology, Temple University School of
Medicine, Phildelphia, PA; 2 Ophthalmology,
Geisinger Medical Center, Danville, PA
6366 — C0143 Subthreshold Micropulse Diode
Laser Photocoagulation (577nm) for Diabetic
Macular Edema in Korean Patients.
Dongkyu
Lee, H.
Kang , H.
Kim, Y.
You, S. Kim, O. Kwon.
Vitreoretinal Center, Nune Eye Hospital, Seoul,
Republic of Korea
6367 — C0144 Non-Vitrectomized Vitrectomy to Manage Coats’ Disease.
Peiquan Zhao .
Ophthalmology, Xinhua Hospital , Shanghai
Jiaotong University , Shanghai , China
6368 — C0145 Retinal Injury from Accidental
Laser Exposure: Evolution of Changes on
SD-OCT and Examination.
Gregory D.
Lee, C.
R.
Baumal , D.
R.
Lally, E.
Reichel, J.
S.
Duker.
Ophthalmology, New England Eye Center , Tufts
Medical Center , Boston , MA *CR
6369 — C0146 POFAL Study: «Protection
Oculaire Face aux Agressions Lasers», Phase I.
Hussam El Chehab 1 , A. Bemelmans 2 , C. Nouvel-
Jaillard 3 , M. Niepon 3 , J. G. Renard 1 .
1 Department of Ophthalmology, Hospital Val de Grace, Paris,
France; 2 Molecular Imaging Research Center /
CEA, Fontenay-Aux-Roses, France;
Institute, Paris, France
3 Vision
6370 — C0147 A new laser induced traumatic optic neuropathy model.
Mary Tapia 1 , X.
Xing 1, 2 , S. Galeb
Bhattacharya
1 , A. Camp
1 , R. K. Lee 1
1 , X. Tong 1, 3 , S. K.
.
1 Bascom Palmer Eye
Institute, U of Miami Miller School of Medicine,
Miami, FL; 2 Tianjin Medical University Eye
Institute, Tianjin Medical University Eye Hospital,
Tianjin, China; 3 Department of Ophthalmology,
Shanghai Eye Disease Prevention and Treatment
Center, Shanghai, China
Exhibit/Poster Hall SA C0148-C0166
Thursday, May 08, 2014 12:00 PM-1:45 PM
Retina
Moderator: Demetrios G. Vavvas
6371 — C0148 Spectrum of Retinal Pigment
Epithelium Abnormalities in Central Serous
Chorioretinopathy as Revealed by Ultra-
Widefield Autofluorescence.
Juliana E.
Boneta 2, 1 , L. A. Yannuzzi
J. Sherman 1, 3
4 , S. Nath 3 , S. J. Bass 1 ,
. 1
New York, NY;
SUNY College of Optometry,
NY; 3
NY; 4
2 Fromer Eye Centers, New York,
Eye Institute & Laser Center, New York,
Vitreous Retina Macula Consultants of New
York, New York, NY *CR
6372 — C0149 Long-Term Impacts of
Antioxidant Supplementation and Smoking
Cessation on Chronic Central Serous
Chorioretinopathy.
Midori Araki, T.
Yasukawa , M.
Ashikari , A.
Kato , N.
Tachi, Y.
Hirano , Y.
Ogura.
Nagoya City University , Nagoya , Japan
6373 — C0150 Recurrence of central serous chorioretinopathy in patients who undergo intraocular surgery with subsequent topical steroid therapy.
Oscar C.
Kuruvilla, N.
Alapati,
H.
Inger, Z.
Peracha, D.
Kim, P.
A.
Edwards.
Ophthalmology, Henry Ford Hospital , Royal Oak,
MI
6374 — C0151 Potential Therapeutic Benefit
Of Melatonin In Refractory Central Serous
Chorioretinopathy.
Jose D.
Luna Pinto, A.
L.
Gramajo, G.
Marquez, V.
Torres , C.
P.
Juarez , R.
E.
Rosenstein . Ophthalmology, Ctr Privado de Ojos
Romagosa Fndtn VER, Cordoba, Argentina
6375 — C0152 Retinal Sensitivity
Changes After Half-time Reduced-Fluence
Photodynamic Therapy for Central Serous
Chorioretinopathy.
Hirotaka Yokouchi , M.
Kitahashi, M.
Kubota , T.
Baba , S.
Yamamoto .
Ophthalmology, Chiba Univ Graduate School of
Med, Chiba, Japan
6376 — C0153 Half-dose versus half-fluence photodynamic therapy for chronic central serous chorioretinopathy.
Ryo Matoba , Y.
Shiode , T.
Kawata , M.
Hosokawa , S.
Kimura , Y.
Morizane , F.
Shiraga.
Okayama university , Okayama, Japan *CR
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
412

Thursday – Posters – 6377 – 6398
6377 — C0154 Quantitatve Evaluation
Of Eplerenone Treatment For Central
Serous Chorioretinopathy (CSCR).
Agustina
Palacio 1 , N. Piri 1 , A. Ozkok 1
Tezel 1, 2 .
1
, S. Schaal 1 , T. H.
Ophthalmology and visual Sciences,
University of Louisville, Louisville, KY;
Louisville, KY
2 Anatomy and Neurobiology, University of Louisville,
6378 — C0155 Eplerenone fails to treat central serous chorioretinopathy.
Harpal Sandhu , D.
G.
Vavvas . Ophthalmology, Massachusetts Eye and Ear
Infirmary, Boston , MA
6379 — C0156 Eplerenone for Treatment of
Chronic Central Serous Chorioretinopathy: A
Retrospective Case Series.
Margaret Greven
Salz 1 , J. D. Pitcher 2 , K. Elliot 3 , C. D. Regillo 2
, J. F. Vander 2
1 , D.
, M.
, Fineman
M. Spirn
PA; 2
2
2
, J. Hsu
.
1
2 , D. H. Fischer 2
Wills Eye Hospital, Philadelphia,
Retina Service, Wills Eye Hospital,
Philadelphia, PA; 3 Thomas Jefferson University
School of Medicine, Philadelphia, PA
6380 — C0157 The Sympatholytic Non-selective
β-blocker PROPRANOLOL as A Non-invasive
Therapeutic Approach for the Treatment of
Chronic Central Serous Chorioretinopathy
(CSC).
Jose A.
Cardillo , M.
W.
Rodrigues, L.
F.
Barroso, R.
C.
Siqueira , R.
Jorge.
Retina , Ribeirão
Preto Medical School University of São Paulo,
Ribeirão Preto, Brazil
6381 — C0158 Central Serous
Chorioretinopathy Treated with
Mineralocorticoid Antagonists: a Retrospective
Study Analyzing the Clinical and Multimodal
Imaging Response to Therapy.
Quraish Ghadiali
J. J. Jung 1, 2 , S. Yu 2, 3 .
1
1 ,
Department
York, NY; 2
, L. A. Yannuzzi 1, 2 of Ophthalmology, New York University, New
Vitreous Retina Macula Consultants of New York, New York, NY; 3 Department of
Ophthalmology, Shanghai First People’s Hospital,
Shanghai Jiaotong University, Shanghai, China
6382 — C0159 Finasteride for Chronic Central
Serous Chorioretinopathy.
Kelly Fujikawa , A.
P.
Patel, L.
S.
Morse.
Department of Opthalmology ,
University of California Davis Eye Center ,
Sacramento , CA
6383 — C0160 Anti-VEGF treatment of
CNVM Secondary to Chronic Central Serous
Retinopathy.
Netan Choudhry . Herzig Eye
Institute, Toronto, ON , Canada
6384 — C0161 Systemic Interferon alpha 2a for treatment of chronic relapsing Central Serous
Chorioretinopathy.
Egbert Matthe , D.
Sandner, L.
E.
Pillunat . Dept of Ophthalmology, University of
Dresden, Dresden, German y
6385 — C0162 Micropulsed Laser Therapy
Outcomes in the Treatment of Chronic Central
Serous Choroidopathy Based on Leakage
Pattern.
Alessandro J. Dare 1
Paganelli 1 , L. C. Castro 1
1, 2 , R. Peroni , F.
Ophthalmology, HOIP -
Hospital de Olhos do Interior Paulista, Araraquara,
Brazil; 2
.
1
Ophthalmology, CRV - Consultores de
Retina e Vítreo, Ribeirao Preto, Brazil
6386 — C0163 Large choroidal blood vessel sign on optical coherence tomography images in acute central serous chorioretinopathy: locational relationship with angiographic findings.
Sung Yong Park, S. Kim, D. Ham.
Ophthalmology, Sung Kyun Kwan University,
Seoul, Republic of Korea
6387 — C0164 Prevalence of the large choroidal blood vessel sign on optical coherence tomography images in central serous chorioretinopathy.
Y. Song 2 , J. Sung 3, 4
Don-Il Ham
, S. Park 1 .
1
1 , S. Kim 1 , S. Kim
Samsung Medical
Center, Ophthal, Sungkyunkwan Univ Sch of
1 ,
Med, Seoul, Republic of Korea; 2 Family medicine,
Samsung Medical Center, Sungkyunkwan Univ Sch of Med, Seoul, Republic of Korea; 3 Epidemiology and Institute of Environment and Health, School of Public Health, Seoul National University, Seoul,
Republic of Korea; 4 4Genomic Medicine Institute
(GMI), Medical Research Center, Seoul National
University, Seoul, Republic of Korea
6388 — C0165 Obscuration of the inner choroidal layer in central serous chorioretinopathy.
Ryo Obata, Y.
Nomura ,
X.
Tan, K.
Azuma, Y.
Yanagi . Department of
Ophthalmology, Univ of Tokyo School of Medicine ,
Tokyo, Japan *CR
6389 — C0166 Subfoveal choroidal thickness of smoking and non-smoking patients with central serous chorioretinopathy.
Yasuki Ito, R.
Maruko ,
Y.
Nagasaka , K.
Oiwa , H.
Terasaki . Ophthalmology,
Nagoya Univ School of Medicine , Nagoya , Japan
Exhibit/Poster Hall SA C0186-C0240
Thursday, May 08, 2014 12:00 PM-1:45 PM
Genetics
Moderators: Elias I. Traboulsi and
Arlene V. Drack
6390 — C0186 Diagnostic Precision in a
Tertiary Care Specialty Retinal Dystrophy
Clinic.
Elias I.
Traboulsi, M.
J.
Marino . Center for Genetic Eye Diseases , Cole Eye Institute,
Cleveland, OH *CR
6391 — C0187 Next-generation Sequencing
Panel for Molecular Diagnosis in the Eye Clinic
-Identification of Novel Mutations and the Saga of Variants of Unknown Significance.
Suma
P. Shankar
Hegde 1 .
1
1
Hutchinson 2
, J. Yan 2
, M.
Human Genetics, Emory University,
Atlanta, GA; 2
, S. R. Lambert
, P. Lenhart 2
2 , A. K.
, V. T. Ciavatta 2
Dept of Ophthalmology, Emory
University, Atlanta, GA
6392 — C0188 Next Generation Approach to
Molecular Diagnosis of Ocular Diseases.
Lee-Jun
C. Wong
G. Wang 1
1 , V. Zhang 1
, J. Wang 1
, Y. Feng 1 , F. Li
, R. A. Lewis 1, 2 .
1
1
, C. K. Truong
Molecular and Human Genetics, Baylor College of Medicine,
Houston, TX; 2 Department of Ophthalmology,
Baylor College of Medicine, Houston, TX
1 ,
6393 — C0189 The Challenges, limitations and uncertainties of whole exome sequencing
(WES) for hereditary ocular disorders.
Maria
Carolina Ortube 1, 2 , A. Martinez 1
M. Gorin 1, 3 .
1
1 , S. P. Strom
Ophthalmology, Jules Stein Eye
,
Institute, UCLA, Los Angeles, CA; 2 Pathology and Laboratory Medicine, University of California
(UCLA), Los Angeles, CA; 3 Human Genetics,
University of California (UCLA), Los Angeles, CA
6394 — C0190 Systematic Analysis of Non-
Protein Coding Sequence Variation Reveals
Putative Pathogenic Mutations Causing
Inherited Human Retinal Disease.
Zachry Soens
J. E. Zaneveld
K. Koenekoop
1
3
, V. Gelowani
, R. Chen 1 .
1
1 , L. Jiang 1 , R. Sui 2 , R.
Molecular and Human
Genetics, Baylor College of Medicine, Houston,
1 ,
TX; 2 Ophthalmology, Peking Union Medical
College Hospital, Beijing, China; 3 Human Genetics and Paediatric Surgery and Ophthalmology, McGill
University Health Centre, Montreal, QC, Canada
6395 — C0191 An algorithm to characterize gene-gene interactions in family-based studies of polygenic disorders of the eye.
Vincent
Raymond
E. Shink 2
1, 2
.
1
, P. Belleau 1 , S. Dubois
Molecular Genetics of Sensory Systems,
CHU de Quebec Research Centre, CHUL Hospital,
Quebec City, QC, Canada; 2
1 , S. Desjardins
Molecular Medicine,
1 ,
Laval University, School of Medicine, Quebec City,
QC, Canada
6396 — C0192 Cortical Patterning Genes are
Associated with Individual Differences in Visual
Orientation Perception.
Patrick T.
Goodbourn 1, 2
G. Bargary 1, 3 , J. M. Bosten
J. Lawrance-Owen 1
1 , R. E. Hogg 1, 4
, J. D. Mollon 1 . 1
, A.
Department of Experimental Psychology, University of
Cambridge, Cambridge, United Kingdom; 2
,
School of Psychology, University of Sydney, Sydney,
NSW, Australia; 3 Division of Optometry and
Visual Science, City University London, London,
United Kingdom; 4
Kingdom
Centre for Vision and Vascular
Science, Queen’s University Belfast, Belfast, United
6397 — C0193 miRNA Mimic Screen to Identify Genetic Pathways Involved in
Maintenance of RPE Phenotype.
Katharina Clore-
Gronenborn 1 , V. Khristov
Miyagishima
Bharti 1 .
1
1 , S. Martin 2
1 , A. Li 1 , M. Zamani
, J. Davis
National Eye Institute, National Institutes of Health, Bethesda, MD; 2 NCATS, National
Institutes of Health, Bethesda, MD
1
1 , K. J.
, S. S. Miller 1 , K.
6398 — C0194 Rapid Identification of
Causative Mutations from Blind Zebrafish by
Whole Exome Sequencing.
Sujuan Jia, Y.
Wang ,
G.
Wu , H.
Henson , M.
R.
Taylor . St Jude Children › s
Research Hospital , Memphis, TN f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
413

Thursday Posters 12:00 pm – 1:45 pm
6399 – 6414 – Thursday – Posters
6399 — C0195 General Survey of Eye Diseases in Laboratory Mouse Strains.
Bo Chang, R.
Hurd , J.
Wang , B.
FitzMaurice, P.
M.
Nishina.
The
Jackson Laboratory , Bar Harbor , ME
6400 — C0196 Genetic background effect on eye phenotype of Le-Cre transgenic mice.
Natalie
Dora 1 , J. Collinson 2 , R. E. Hill 3 , J. D. West 4 . 1 Centre for Integrative Physiology, School of Biomedical
Sciences, University of Edinburgh, Edinburgh,
United Kingdom; 2 Institute of Medical Sciences,
University of Aberdeen, Aberdeen, United
Kingdom; 3 Medical Research Council Human
Genetics Unit, Medical Research Council Institute of Genetics and Moleular Medicine, University of
Edinburgh, Edinburgh, United Kingdom; 4 Centre for Integrative Physiology, School of Clinical
Sciences, University of Edinburgh, Edinburgh,
United Kingdom
6401 — C0197 An Intronic SINE Insertion in FAM161A that Causes Exon-skipping is
Associated with Progressive Retinal Atrophy in Tibetan Spaniels and Tibetan Terriers.
Louise M. Downs 1, 2 , C. S. Mellersh 2 . 1 Section of
Ophthalmology, School of Veterinary Medicine,
University of Pennsylvania, Philadelphia,
PA; 2 Kennel Club Genetics Centre, Animal Health
Trust, Newmarket, United Kingdom
6402 — C0198 Functionality Characterization of rs2229094 (T>C) polymorphism and LTα
Expression in Human Retinas.
Santiago
Delgado-Tirado 1 , S. Pastor 1, 2 , I. Rodriguez-
Hernandez 2, 3 , J. Rojas 1 , L. Gonzalez-Buendia 1 ,
R. Gonzalez-Sarmiento 2, 3 , J. Pastor 1 . 1 Instituto de Oftalmobiologia Aplicada (IOBA), University of Valladolid, Valladolid, Spain; 2 Unidad de
Medicina Molecular, University of Salamanca,
Salamanca, Spain; 3 Instituto de Biologia Molecular y Celular del Cancer (IBMCC) Consejo Superior de Investigaciones Cientificas (CSIC) Instituto de
Investigacion Biomedica de Salamanca (IBSAL),
University of Salamanca, Salamanca, Spain
6403 — C0199 Genetic Variation is the
Major Determinant of Individual Differences in Leukocyte Endothelial Adhesion.
Vidhya
R.
Ra o 1 , S. Chen
Bogaard 1
Huang 5
4 , K. P. Winkler
, J. Rehman 2
, M. A. Grassi 1
1 , W. Zhang 3
, A. B. Malik 2
. 1
, J.
, N. J. Cox 5 , R.
Ophthalmology and Visual
Sceinces, University of Illinois, Chicago, Chicago,
IL; 2 Department of Pharmacology, University of Illinois, Chicago, Chicago, IL; 3
Chicago, IL; 4
Department of Pediatrics, University of Illinois, Chicago,
Cellular Screening Center, Institute for Genomics and Systems Biology, University of Chicago, Chicago, IL; 5 Section of Genetic
Medicine, University of Chicago, Chicago, IL
6404 — C0200 Tbx3 is required at neural plate stages for normal eye formation in Xenopus laevis.
Zahra Motahari 1, 2 , A. S. Viczian 1, 2 , M.
E. Zuber 1, 2 .
1 Ophthalmology, Biochemistry &
Molecular Biology, SUNY Upstate Medical university, Syracuse, NY; 2 The Center for Vision
Research and SUNY Eye Institute, SNY Upstate
Medical University, Syracuse, NY
6405 — C0201 QTL rich region of Chr1 specific gene, Pfdn2, regulates Sncg expression in mouse RGC.
Sumana R.
Chintalapudi 1 , V.
Morales-Tirado 1, 2 , R. W. Williams 3 , M. M.
Jablonski 1, 3 . 1 Ophthalmology, Hamilton Eye
Institute, University of Tennessee Health Science
Center, Memphis, TN; 2 Microbiology, Immunology and Biochemistry, University of Tennessee Health
Science Center, Memphis, TN; 3 Department of Anatomy and Neurobiology, University of
Tennessee Health Science Center, Memphis, TN
6406 — C0202 Genome-wide Linkage Analysis
Using Large Consanguineous Pedigrees from
South India Identifies New Loci for Ocular
Quantitative Traits.
Friedman 3 , L. Vijaya
J. L. Wiggs 1 . 1
Baojian Fan
Marie Sharmila 2 , N. Soumittra 2
4 , J. L. Haines
1
5
, P. Ferdina
, S. Sripriya 2 , D. S.
, R. J. George 4 ,
Dept of Ophthalmology Harvard Med
Sch, Massachusetts Eye & Ear Infirmary, Boston,
MA; 2 SNONGC Department of Genetics and
Molecular Biology, Vision Research Foundation,
Chennai, India;
Wilmer Eye Institute, Baltimore, MD;
Research Foundation, Sankara Nethralaya, Chennai,
India; 5
3 Johns Hopkins Medical School,
4 Medical
Center for Human Genetic Research,
Vanderbilt University School of Medicine,
Nashville, TN
6407 — C0203 Analysis of intra-ocular pressure using a combination of next generation sequencing data and imputation-based method in the TwinsUK cohort.
Abhishek Nag, P.
G.
Hysi ,
C.
J.
Hammond.
Dept of Twin Research , King › s
College London , London , United Kingdom
6408 — C0204 Family-based Genomewide Association Study in South Indian
Consanguineous Pedigrees Identifies an
Association between WNT7B and Central
Corneal Thickness.
Xueli Chen
Ferdina Marie Sharmila 2
1 , B. Fan
, N. Soumittra 2
1 , P.
, S.
5 Sripriya 2 , D. Friedman
R. J. George 4
3 , L. Vijaya
, J. L. Wiggs 1 . 1
4 , J. Haines
Ophthalmology,
,
Harvard Medical School, Massachusetts Eye & Ear
Infirmary, Boston, MA; 2 SNONGC Department of
Genetics and Molecular Biology, Vision Research
Foundation, Chennai, India; 3 Johns Hopkins
Medical School, Wilmer Eye Institute, Baltimore,
MD; 4 Medical Research Foundation, Sankara
Nethralaya, Chennai, India; 5 Center for Human
Genetic Research, Vanderbilt University School of
Medicine, Nashville, TN
6409 — C0205 Congenital Stromal Corneal
Dystrophy is not reproduced in 952delT Dcn
Transgenic Mice.
Anne Christensen Mellgren 1, 3 ,
O. Bruland 4 , A. Vedeler 2 , J. Schönheit 5 , C. Bredrup 3 ,
P. Knappskog 4 , E. Rodahl 1, 3 .
1 Department of
Clinical Medicine, University of Bergen, Bergen,
Norway; 2 Department of Biomedicine, University of Bergen, Bergen, Norway; 3 Department of
Ophthalmology, Haukeland University Hospital,
Bergen, Norway; 4 Center for medical genetics and molecular medicine, Haukeland University
Hospital, Bergen, Norway; 5 Norwegian Veterinary
Institute, Bergen, Norway
6410 — C0206 Determining the genetic basis of familial Keratoconus by autozygosity mapping and whole exome sequencing.
Layal
Abi Farraj
1
Sleymane
1 , S. Siddiqui
1
1, 2 , A. Rice 3 , G. Abi-
, C. F. Inglehearn 1 , M. Ali 1 4 , C. Toomes .
Ophthalmology and Neuroscience, Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, United Kingdom; 2 Department of Ophthalmology, Saint James, Leeds, United
Kingdom; 3 East Kent Hospitals University
NHS Foundation Trust, Kent, United Kingdom;
4 Department of Laboratory Science and Technology,
American University of Science and Technology,
Ashrafieh, Lebanon
6411 — C0207 Genetic variations of antioxidant related genes are associated with susceptibility to Keratoconus in Korean patients.
Jeewon Mok 1 , K. Na 1, 2 , M. Kim 1 , H. Ju 1 ,
Y. Yoo 1, 2 , C. Joo 1, 2 .
1 Catholic Institutes of Visual
Science, Catholic Univ Korea, Seoul, Republic of
Korea; 2 Seoul St. Mary’s hospital Eye Institute, The
Catholic University of Korea, Seoul, Republic of
Korea
6412 — C0208 Identification and segregation analysis of rare ZNF469 coding variants in familial Keratoconus.
Alice Davidson 1
E. Borasio 2 , V. Cipriani
, S. J. Tuft 5, 1
1 , P. Liskova 3 , V.
, A. J. Hardcastle 1 .
1
,
Plagnol 4 UCL,
Institute of Ophthalmology, London, United
Kingdom; 2 Moorfields Eye Hospital, Dubai, United
Arab Emirates; 3 Institute of Inherited Metabolic
Diseases, Charles University, Prague, Czech
Republic; 4 UCL, Genetics Institute, London,
United Kingdom; 5 Moorfields Eye Hospital NHS
Foundation Trust, London, United Kingdom
6413 — C0209 High Resolution in-vivo Imaging in Patients with PAX6 Mutations.
Mervyn
G.
Thomas 1 , V. Sheth 1 , W. Chan 2 , C. Andrews 2 ,
E. C. Engle 2, 3 , I. Gottlob 1 .
1 Ophthalmology
Group, University of Leicester, Leicester, United
Kingdom; 2 Department of Neurology, Boston
Children, Boston, MA; 3 Departments of Neurology,
Ophthalmology, Medicine (Genetics), Harvard
Medical School and Boston Children, Boston, MA
6414 — C0210 Transcriptional characterization of the nonsense allele of FOXE3 responsible for
Peters anomaly.
M. W. Lee 3
N. Pourmand 3
A. S. Riazuddin 1 .
Shahid
, Z. Ma
1
4
Y.
Khan
, S. Riazuddin
, J. F. Hejtmancik 4
1
5
, A. O. Khan 2
, R. N. Cole 6
, J. D. Gottach 1
Ophthalmology-Cornea and
Anterior Segment Service, The Wilmer Eye
Institute, Baltimore, MD; 2 Division of Pediatric
Ophthalmology, King Khaled Eye Specialist
,
,
,
Hospital, Riyadh, Saudi Arabia; 3 Department of Biomolecular Engineering, University of
California Santa, Santa Cruz, CA; 4 Ophthalmic
Genetics and Visual Function Branch, National
Eye Institute, Bethesda, MD; 5 National Centre of
Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan;
University, Baltimore, MD
6 Mass Spectrometry and Proteomics Core Facility, The Johns Hopkins
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
414

Thursday – Posters – 6415 – 6432
6415 — C0211 Identification two novel
PITX2 gene mutations in Chinese patients with distinct ocular phenotypes in Axenfeld-Rieger syndrome.
Xiaohui Zhang, J.
Chen , K.
Xu , Y.
Li .
Beijing Institute of Ophthalmology, Beijing, China
6416 — C0212 Discovery of a novel deletion in PITX2 by dye-based quantitative
PCR confirms that haploinsufficiency is a disease-causing mechanism for Axenfeld-
Rieger Syndrome.
Morteza Seifi
E. Abdalla 2 , G. Elhady 2
1 , T. Footz 1
, R. Ritch 4
,
, , K. Nabil 3
M. A. Walter 1 .
1 Department of Medical
Genetics, University of Alberta, Edmonton,
AB, Canada; 2 Department of Human Genetics,
Medical Research Institute, Alexandria University,
Alexandria, Egypt; 3 Department of Ophthalmology,
Faculty of Medicine, Alexandria University,
Alexandria, Egypt;
York, NY
4 Einhorn Clinical Research
Center, New York Eye and Ear Infirmary, New
6417 — C0213 Hereditary cataract in
Bichon Frisé dogs: Genome-wide association study suggests a new preliminary locus finding.
Maria K.
Kaukonen 1, 2 , S. J. Ahonen 1, 2 ,
H. Lohi 1, 2 . 1 Molecular Neurology, University of Helsinki, Helsinki, Finland; 2 The Folkhälsan
Institute of Genetics, Helsinki, Finland
6418 — C0214 Novel Indoleamine
2, 3-Dioxygenase; (IDO1) gene mutation in the
Pathogenesis of age-related cataract.
Mamata
Manne
2
1, 2 , P. Gunda
N. Thurlapati 3, 1
1, 2 , R. K. Kondreddy 2, 1
, P. Tirunilai 1, 2
Sarojini Devi Eye Hospital, Mehidipatnam,
Hyderabad, India; 3
.
1
,
Department of Genetics, Osmania University, Hyderabad,
India;
Department of Zoology,
Osmania University, Hyderabad, India
6419 — C0215 Identification of multiple genetic susceptibility loci for Behçet’s disease.
Masaki
Takeuchi 1, 2 tutkun 3
, N. Mizuki
, Y. Ozyazgan 3
2 , A. Meguro
, S. Ohno
Kastner 1 , E. F. Remmers
Health, Bethesda, MD; 2
1 . 1
4
2 , I. Tugal-
, A. Gül 3 , D. L.
National Institutes of
Ophthalmology, Yokohama
City University Graduate School of Medicine,
Yokohama, Japan;
Turkey; 4
3 Istanbul University, Istanbul,
Ophthalmology, Hokkaido University
Graduate School of Medicine, Sapporo, Japan
6420 — C0216 Association analysis of
TGFBR3 gene with Behcet’s Disease and
Idiopathic Intermediate Uveitis in a Caucasian population.
Robert J.
Barr y 1, 2
Wallace 1, 2 , P. I. Murray 2, 1
, J. Alsalem
, J. Curnow 1, 2 . 1
1 , G. R.
Centre for Translational Inflammation Research,
University of Birmingham, Birmingham, United
Kingdom;
Kingdom
2 Academic Unit of Ophthalmology,
University of Birmingham, Birmingham, United
6421 — C0217 A molecular genetics study on Stevens-Johnson Syndrome.
Sushil Kumari
Sangwan 1
T. Agarwal
India Institute of Medical Sciences, New Delhi,
India; 2 Dr.Rajendra Prasad Centre for Opthalmic
Sciences, All India Institute of Medical Sciences,
New Delhi, India; 3 Dermatology and Venerology,
All India Institute of Medical Sciences, New Delhi,
India; 4 Centre for Eye Research, University of
Melbourne, Melbourne, SA, Australia
6422 — C0218 Identification of a Novel
OCRL Mutation in Oculocerebrorenal
Syndrome of Lowe.
Hu 1
, A. Sharma
2 , R. Vajpayee
, M. J. Turner
Y. Sun 1 .
1
Indianapolis, IN;
2
1 , N. Sharma
4, 2 .
1 Anatomy, All
Na Luo 1
2 , N. Khanna
, L. C. Mairs 1
, D. E. Neely 1
Ophthalmology, Indiana University,
3
2
,
,
2 Dermatology, Indiana University,
Indianapolis, IN *CR
, X.
, D. F. Spandau
6423 — C0219 Phenotypic features related to Wolfram syndrome in 17 families.
Stephanie
Leruez
V. Procaccio Reynier
Milea
1
1, 4
, V. Marion
C. P. Hamel
1 , J. Grenier
6, 5 , C. Orssaud
2, 4
7
6 , X. Zanlonghi
, C. Vignal-Clermont
, P. Bonneau 2, 4 , D.
.
1 Ophthalmology, CHU Angers,
Angers, France;
Angers, France;
2
3
Genetics, CHU Angers,
Ophthalmology, Clinique
Sourdille, Nantes, France; 4
3 ,
8 ,
Angers, France;
France; 6
5
INSERM U1083,
INSERM U1051, Montpellier,
Ophthalmology, CHRU Montpellier,
Montpellier, France; 7 Ophthalmology, Hôpital
Georges Pompidou, Paris, France;
Fondation Rotschild, Paris, France
8 Ophthalmology,
6424 — C0220 A Rare Syndrome:
Hypotrichosis with Juvenile Macular Dystrophy
(HJMD).
Maya Bita r
Oliveira 2 , N. F. Azar
Maumenee 1 .
Sao Paulo, Brazil;
Paulo, Brazil
1
1
1 , B. Y. Milani 1 at Chicago, Chicago, IL;
3
2
, R. Ferreira
, J. Ferraz Sallum 3 , I. H.
Ophthalmology, University of Illinois
Santa Casa de São Paulo,
Ophthalmology, UNIFESP, Sao
6425 — C0221 Homozygous deletion of glutamate receptor gene GRID2 causes new hotfoot mutant phenotype, characterized by early-onset cerebellar ataxia and retinal dystrophy.
Kristof Van Schil 1 , M. Karlstetter 3 , F.
Meire 2 , M. Bauwens
E. Scheiffert
De Baere 1
1 , H. Verdin
3 , N. Deconinck 4
1 , F. Coppieters
, T. Langmann 3
1
, E.
,
.
1 Center for Medical Genetics, Ghent
University and Ghent University Hospital, Ghent,
Belgium; 2 Department of Pediatric Ophthalmology,
Queen Fabiola Children’s University
Hospital, Brussels, Belgium; 3 Department of
Ophthalmology, University of Cologne, Cologne,
Germany; 4 Department of Pediatric Neurology,
Queen Fabiola Children’s University Hospital,
Brussels, Belgium
6426 — C0222 Pineal gland evaluation through polysomnography (PSG) in a patient with juvenile X linked retinoschisis.
Luciana
C. Lavigne
Mendonca
J. Chiang 2
1
1 , A. T. Rassi
, I. B. Silva 1
1 , T. Oliveira 1 , L. M.
, M. P. Avila
, L. A. Gabriel
CEROF, Goiania, Brazil;
1 .
2
1
1 , L. F. Chaves
Ocular Genetics,
Casey Molecular
Diagnostic laboratory, Casey Eye Institute,
Portland, OR
1 ,
6427 — C0223 Non-Truncating Homozygous
Deletion in CACNA2D4 Mimicking Oligocone
Trichromacy.
Ajoy Vincent 1, 2 , S. Deshmukh 1
T. Wright 1
Heon 1, 2 .
1
, Y. Sanchez 1 , C. A. Westall 1 , E.
,
Ophthalmology and Vision Sciences,
Hospital for Sick Children, Toronto, ON,
Canada; 2 Genetics and Genome Biology Program,
Hospital for Sick Children, Toronto, ON, Canada
6428 — C0224 High resolution images of cone photoreceptors with Bietti Crystalline dystrophy associated with CYP4V2 mutation.
Kiyoko
Gocho 1
Kameya
, K. Akeo
1 , K. Yamaki
A. Mizota 2, 4
1 , S. Kikuchi
1 , T. Hayashi
, H. Takahashi 5 .
1
1 , A. Usui 2 , S.
3 , H. Tsuneoka
Ophthalmology,
Nippon Med Univ, Chiba Hokusoh Hosp, Inzai,
Japan; 2 Ophthalmology, Juntendo University
Urayasu Hospital, Urayasu, Japan;
3 ,
The Jikei University School of Medicine, Tokyo,
Japan; 4 of Medicine, Tokyo, Japan;
3 Ophthalmology,
Ophthalmology, Teikyo University School
5 Ophthalmology, Nippon
Medical School, Tokyo, Japan
6429 — C0225 In Search of Novel Disease-
Causing Genes of Familial Exudative
Vitreoretinopathy (FEVR) - a Genetically
Heterogeneous Eye Disease.
Mingchu Xu 1, 2
S. Salvo
Nguyen 5
1, 3 , H. Wang
, H. Luo 4
1, 2 , K. Wang
, K. Zhang
2 , Y. Li
4 , R. Chen
1, 2
1, 2 .
1
, J.
, D. H.
Human
Genome Sequencing Center, Baylor College of
Medicine, Houston, TX; 2 Molecular and Human
Genetics, Baylor College of Medicine, Houston,
TX; 3 Structural and Computational Biology &
Molecular Biophysics Graduate Program, Baylor
4 Department College of Medicine, Houston, TX; of Ophthalmology, University of California, San
Diego, San Diego, CA; 5 School of Medicine,
University of California, San Diego, San Diego, CA
6430 — C0226 Next generation sequencing
(NGS) of CHM, RPRG and RP2 genes identifies novel Indian mutations in two families with Choroideremia.
Rajani Batt u
P. Murthy
Reddy 1
2 , P. Srinivasan 1 , R. Shetty 3 , K.
Vitreoretina, Narayana Nethralaya,
1 ,
4 .
Bangalore, India; 2 Vitreoretina, Vittala International
Institute of Ophthalmology, Bangalore,
India; 3 Electrophysiology, Narayana Nethralaya,
Bangalore, India;
India *CR
4 Strand Life Sciences, Bangalore,
6431 — C0227 Spectrum of CHM mutations, structural retinal features and their progression in choroideremia patients within the UK.
Mariya
Moosajee
T. Moore
1, 3 , S. C. Ramsden
1, 3 , A. Webster 1 .
1
2 , G. C. Black 2 , A.
Ocular Biology and
Therapeutics, UCL Institute of Ophthalmology,
London, United Kingdom; 2 Genetic Medicine,
Central Manchester University Hospitals
NHS Foundation Trust, Manchester, United
Kingdom; 3 Genetics, Moorfields Eye Hospital NHS
Foundation Trust, London, United Kingdom
6432 — C0228 New genetic aspects and particular ocular manifestations of a child with Hallermann Streiff syndrome.
Alexandra
Oltea Puiu
I. Puiu 2, 1
1 , F. Burada
, C. Mocanu
2, 1
2, 1 .
1
, A. Stefanescu-Dima
Emergency Clinical
Hospital, Craiova, Romania; 2 University of
Medicine and Pharmacy, Craiova, Romania
2, 1 , f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
415

Thursday Posters 12:00 pm – 1:45 pm
6433 – 6444 – Thursday – Posters
6433 — C0229 Whole Exome Sequencing for
Sjögren’s Reticular Dystrophy.
Scott E. Brodie 1 ,
V. Rudrapatna 1
Mahajan 2
P. Leroy 3
, M. Linderman
, H. Shah 2 , P. Devchand
, G. C. Black 4 .
1
2 , G. Diaz
2
2 , M.
, E. Schadt 2 , B.
Ophthalmology, Icahn
School of Medicine at Mount Sinai, New York,
NY;
NY; 3
2 Genetics and Genomic Sciences, Icahn
School of Medicine at Mount Sinai, New York,
Ophthalmology and Medical Genetics, Ghent
University, Ghent, Belgium;
Kingdom
4 Genomic Medicine,
University of Manchester, Manchester, United
6434 — C0230 Mutation identification in the family with autosomal recessive encephalocele and retinal detachments originally described by
Knobloch.
Behrad Y.
Milani 1
Maumenee 1 . 1
, C. Summers 2 , I. H.
Ophthalmology, Univ of Illinois at
Chicago, Chicago, IL; 2 OPhthalmology, University of Minnesota, Minnesota, MN
6435 — C0231 In-depth analysis of the
COL2A1 gene in lattice degeneration of the retina.
Akira Meguro
Ota 3 , H. Inoko 4
Japan; 2
.
1
1 , H. Ideta 2 , R. Ideta 2 , M.
Department of Ophthalmology,
Yokohama City Univ School of Med, Yokohama,
3
Ideta Eye Hospital, Kumamoto, Japan;
Department of Legal Medicine, Shinshu University
School of Medicine, Matsumoto, Japan; 4 Tokai
University School of Medicine, Isehara, Japan
6436 — C0232 Investigation of the Role of ADAMTSL4 in an atypical Marfan syndrome population.
Taie 1, 2 . 1
Andrea L.
Vincen t 1, 2 , W. Ikink 1 , R. Al
Ophthalmology, New Zealand National
Eye Centre, University of Auckland, Auckland,
New Zealand;
New Zealand
2 Eye Department, Greenlane Clinical
Centre, Auckland District Health Board, Auckland,
6437 — C0233 Characterization of a Novel
OPA1 Mouse Model by Light and Transmission
Electron Microscopy.
Anh H. Pham 1, 2
Cisneros 1 , B. X. Pan 1 , M. Zaninello 3
1
, F. N. Ross-
, L. Scorrano 3,
4 , V. Carelli 5, 6 , A. A. Sadun .
1 Ophthalmology,
University of Southern California, Los Angeles,
CA; 2 Biology and Biological Engineering,
California Institute of Technology, Pasadena, CA;
3 Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, Padova, Italy; 4
University of Padova, Padova, Italy; 5
Biology,
IRCCS
Institute of Neurological Sciences of Bologna,
Bellaria Hospital, Bologna, Italy;
Bologna, Bologna, Italy
6 Biomedical and
NeuroMotor Sciences (DIBINEM), University of
6438 — C0234 Screening the DNA of Ocular
Albinism Patients for Possible Mutations in
GNAI3 (Guanine Nucleotide Binding Protein,
Alpha Inhibiting Activity Polypeptide 3 gene).
Alejandra Young
Farber 1, 2 .
1 Jules Stein Eye Institute, UCLA, Los
Angeles, CA; 2 Molecular Biology Institute, UCLA,
Los Angeles, CA;
Houston, TX
3
1, 2 , R. A. Lewis 3 , D. B.
Department of Molecular and
Human Genetics, Baylor College of Medicine,
6439 — C0235 A Cross Sectional Examination of BCVA by Specific Type of Albinism.
Caitlin
Nosano v 1 , A. Holleschau 2 , C. Summers 2
University, Saint Paul, MN; 2
. 1 Hamline
Ophthamology &
Visual Neurosciences, University of Minnesota,
Minneapolis, MN
2
6440 — C0236 Loss of Paternal Sperm DNA integrity in Non- familial Retinoblastoma.
Shiv
Basant Kumar
R. Dada 1 .
1
1 , B. Chawla 2 , R. Seth 3 , S. Gautam 1
Department of Anatomy, All India
Institute of Medical Sciences, New Delhi, India;
,
Retinoblastoma Clinic, All India Institute of
Medical Sciences, New Delhi, India; 3 Department of Pediatrics, All India Institute of Medical
Sciences, New Delhi, India
6441 — C0237 Novel Mutations in the RB1
Gene in Retinoblastoma patients with treatment failure.
Leen Abu Safieh , S.
Al Mesfer , M.
W.
Othman , M.
Karaoui, H.
Al Katan, D.
Edward .
Research Department , King Khalesh Eye Specialist
Hospital , Riyadh , Saudi Arabia
6442 — C0238 Identification of a Small Cohort of Genes That Might Drive Metastases in Uveal
Melanoma.
R. Yates 2, 1
Morales 1, 3 . 1
Mercy Kibe
, J. J. Steinle 1
1 , J. J. Toutounchian
, M. W. Wilson 1
2 ,
, V. M.
Ophthalmology, Hamilton Eye
Institute, University of Tennessee Health Science
Center, Memphis, TN; 2 Pharmaceutical Sciences,
University of Tennessee Health Science Center,
Memphis, TN; 3 Microbiology, Immunology and
Biochemistry, University of Tennessee Health
Science Center, Memphis, TN
6443 — C0239 Clinical characteristics of uveal melanoma in patients with germline BAP1 mutations.
A. Lane
Kim 1 . 1
1
Mrinali Pate
, K. Mayne 2 l 1 , M. M. DeAngelis
, E. S. Gragoudas 1 , I. K.
Ophthalmology, Mass Eye and Ear
Infirmary, Harvard Medical School, Boston,
2 ,
MA; 2 Ophthalmology, University of Utah, Salt Lake
City, UT
6444 — C0240 Aneuploidy of chromosome 3 and 4 in human uveal melanomas detected by fluorescence in situ hybridization.
Zita Steiber 1
E. Sipos 2
,
, K. Hegyi 3 , G. Halmos 2 , G. Mehes 3 , A.
Department of Ophthalmology, University Treszl 2 .
1 of Debrecen, Debrecen, Hungary; 2 Department of
Biopharmacy, University of Debrecen, Debrecen,
Hungary; 3 Department of Pathology, University of
Debrecen, Debrecen, Hungary
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/amindices .
416

Hall SB
Thursday, May 08, 2014 2:00 PM-3:15 PM
An internationally recognized pioneer in retinal gene therapy, Jean Bennett has developed gene transfer approaches to test treatment strategies for retinal degenerative and ocular neovascular diseases, to elucidate retinal differentiation pathways and to identify pathogenetic mechanisms that lead to blindness. Her laboratory has developed gene transfer approaches to treat inherited diseases resulting in vision loss and studied immune response of the eye to viral vectors which characterizes and utilizes cell-specific promoters for the delivery of therapeutic nucleic acids. Her research has established the scientific underpinnings that made it possible to test the first potential definitive retinal gene therapy treatment for patients with blinding retinal degenerations.
Bennett will focus on her team’s experiences in developing retinal gene therapy and, through an interactive presentation, will present examples of opportunities, surprises, challenges and successes that could confront new investigators.
6445 — 2:00 Seeing the Light with Retinal
Gene Therapy: Things You Wished You’d
Known Early on Your Way to Late-Stage
Trials.
Jean Bennett.
310 Stellar-Chance Labs ,
University of Pennsylvania , Philadelphia , PA
Thursday – Keynote – 6445 f Refer to the Program Number in the Clinical Trial (CT) Registration Index. * CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
417

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418