D:\106746459.doc Department of Health West Midlands Quality, Innovation, Productivity & Prevention Breastfeeding & Infant Feeding 1. INTRODUCTION/OVERVIEW OF WEST MIDLANDS There is clear evidence that breastfeeding has positive health benefits for both mother and baby in the short and longer-term (beyond the period of breastfeeding)1. Breast milk is the best form of nutrition for infants and exclusive breastfeeding is recommended for the first six months of an infant’s life. Thereafter, breastfeeding should continue for as long as the mother and baby wish, while gradually introducing a more varied diet. Babies who are not breast-fed are many times more likely to acquire illnesses such as gastroenteritis and respiratory infections in the first year 2. In addition, there is some evidence that babies who are not breast-fed are more likely to become obese in later childhood3,4. Mothers who do not breastfeed have an increased risk of breast and ovarian cancers and may find it more difficult to return to their pre-pregnancy weight5. Within the West Midlands, breastfeeding initiation rates have risen from 53.0% in 2005/06 to 66.6% in 2009/106. The Public Health White Paper also emphasises that public health evaluation and research will be critical in enabling public health practice to develop into the future and address key challenges and opportunities, such as how to handle the wider determinants of health and how to use behaviour change science to support better more cost effective practice. This is supported by the setting up of a new School for Public Health Research and a Policy Research Unit on Behaviour and Health. Public Health England, the new service that will be part of the Department of Health, will be expected to properly resource research into interventions happening outside the NHS. Public Health England and others will work together to identify research priorities and use the best evidence and evaluation and will support innovative and cost effective approaches to behaviour change. 2. OVERALL RECOMMENDATIONS Infants Babies who are not breast-fed are many times more likely to acquire illnesses such as gastroenteritis and respiratory infections in the first year7. There is some evidence that babies who are not breastfed are more likely to become obese in later childhood8,9. Mothers Mothers who do not breastfeed have an increased risk of breast and ovarian cancers and may find it more difficult to return to their pre-pregnancy weight10. Breastfeeding can protect mothers against breast cancer; the relative risk of 1 D:\106746459.doc cancers decreases by 4.3% for every 12 months of breastfeeding. This can lead to 145 few cases every year11. NICE uses a threshold of £20,000 - £30,000 per QALY to assess cost effectiveness. Even if the scheme has a net cost, it would still be cost effective if the QALY gain from a reduction in infection and breast cancer is achieved at less than £20,000 - £30,000 per QALY. Enhanced staff contact (which was additional skilled professional support in hospital) was found to be more effective and less costly than normal staff contact, both in the base case and the sensitivity only scenarios. 3. EVIDENCE ON SPECIFIC INTERVENTIONS The Baby Friendly Initiative (BFI), produced by WHO and UNICEF, accredits maternity and community healthcare facilities that have implemented best practice for breastfeeding and have passed an external assessment12. It has been endorsed by NICE as the minimum standard for breast feeding management 13. Below are components of BFI as well as other initiatives for the promotion of breastfeeding. BFI Step 1: Have a written breastfeeding policy that is routinely communicated to all healthcare staff14 There are few studies that have looked specifically at the effectiveness of a breastfeeding policy on breastfeeding rates. However, the studies included in this review seem to indicate that breastfeeding policies do appreciably improve breastfeeding rates although this has not been definitively demonstrated. Taken in combination with the other steps of the BFI, a breastfeeding policy is an important starting point and can be used to implement the other steps of the BFI. BFI Step 2: Train all healthcare staff in the skills necessary to implement the breastfeeding policy There is a paucity of data on the individual effect of training healthcare staff on breastfeeding policy. The one non-randomised controlled quasi-experimental study included in this review15 demonstrated a markedly positive effect on breastfeeding rates of training in several steps of the BFI in a developing country. Training of healthcare staff will be a pre-requisite to implementing the other steps of the BFI. BFI Step 3: Inform all pregnant women about the benefits and management of breastfeeding16 Individual educational interventions appear to be variably effective in socio-economically deprived populations. Group discursive educational sessions on breastfeeding, however, however appear to be effective in low-income and minority groups17. There is also some evidence that showing mothers how to breastfeed and express breast milk improves exclusive breastfeeding rates18. 2 D:\106746459.doc BFI Step 4: Help mothers initiate breastfeeding soon after birth19 This component appears to have a positive effect on breastfeeding rates including in socio-economically deprived populations. Early breastfeeding initiation and skin-to-skin contact should be encouraged. BFI Step 6: Give newborn infants no food or drink other than breast milk, unless medically indicated20 The majority of evidence points towards routine nutritional supplementation reducing breastfeeding rates. Exclusive breastfeeding should therefore be encouraged unless medically indicated. BFI Step 7: Practice rooming-in, allowing mothers and infants to remain together 24 hours a day21 Although the evidence around rooming-in remains weak, it does point towards a positive effect on breastfeeding rates and should therefore be encouraged. BFI Step 8: Encourage breastfeeding on demand22 A weak evidence base suggests breastfeeding on demand improves breastfeeding rates beyond one month23,24. This is likely to be more feasible when rooming-in is practiced. BFI Step 9: Give no artificial teats or dummies to breastfeeding infants25 The evidence around the harms of artificial teats is ambiguous but several observational studies indicate that they may reduce breastfeeding rates in both high and low income settings26,27,28. It therefore seems reasonable to avoid provision of artificial teats and pacifiers to breastfeeding infants. Do not provide commercial discharge packs promoting formula milk Two meta-analyses29,30 suggest that provision of commercial discharge packs with formula milk is detrimental to breastfeeding rates and should therefore be prevented. BFI Step 10: Foster the establishment of breastfeeding support groups and refer mothers to them on discharge from the hospital or clinic31 This was the only aspect of the BFI for which economic data was available. Jacklin’s (2007) economic analysis showed that peer support groups fall within the NICE threshold for cost effectiveness. A systematic review by NICE32 showed that breastfeeding support from both peers and professionals is effective at increasing any breastfeeding among women who plan to breastfeed. Its effect on exclusive breastfeeding among socially disadvantaged women however is weak. 3 D:\106746459.doc BFI This combined intervention has been demonstrated to improve breastfeeding rates in one large cluster RCT33 by 36.9% at 3 months following 12 to 16 months of implementation in Belarus and two before-after studies34,35. Similar findings were also observed in Gateshead, UK36. The marked findings of these studies suggest a synergistic effect of the multiple components of the BFI and that complete implementation may be more effective than isolated interventions. See Appendix 1 - Evidence for Breastfeeding Initiatives for full results and references, prepared by Shamil Haroon, Sandwell PCT. 4. COSTS AND COST EFFECTIVENESS Breastfeeding Benefits to Infants and Mothers: Cumulative Annual Savings in NHS Treatment Costs37 An increase of 10 percentage points in prevalence at 6 months means that 60,000 extra infants are breast-fed every year, providing estimated annual savings to the NHS in treatment costs as follows38,39. See also the Financial Benefits of Improving Health of Low Income Households (Appendix 2). Otitis Meida Gastroenteritis Asthma Lower Respiratory Tract Infection Breast Cancer Total Annual Savings 5. £0.5 million £2.3 million £2.6 million £0.8 million £0.9 million ---------------£7.1 million FURTHER READING NICE Public Health Guidance 11: Maternal and Child Health – ‘Improving the Nutrition of pregnant and breastfeeding mothers in low income households & NICE Public Health Guidance 11: Costing Statement Maternal and Child Nutrition: http://guidance.nice.org.uk/PH11/guidance/pdf/English NICE Clinical Guidance 37, “Routine Postnatal Care of Women and Their Babies”, includes clear recommendations and a costing report template to support implementation and calculating national and local costs and savings including costs in relations to implementing Breastfeeding Initiative: http://www.nice.org.uk/nicemedia/pdf/CG37NICEguideline.pdf Increasingly breastfeeding prevalence contributes to reduction in health service costs. NICE Costing Template, NICE 37, 2006: “Postnatal Care: Routine Postnatal Care of Women and their Babies Costing Report: Implementing Nice Guidance in England”: http://www.nice.org.uk/nicemedia/pdf/implementation_tools/cg37costingreport.d oc Appendix 3 - obesity and breastfeeding - a review of the evidence Financial Benefits Associated with Breastfeeding © UNICEF UK/Jill Jennings 2006: www.babyfreindly.org.uk (see Appendix 2) Department of Health: Commissioning Local Breastfeeding Support Services: consolidates the case for breastfeeding care and support as an integral part of local strategies to improve child health and reduce health inequalities and 4 D:\106746459.doc signposts commissioners to sources of policy, practice and evidence. http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolic yAndGuidance/DH_106501 Breastfeeding Promotion for Infants in Neonatal Units: A systematic review and economic analysis, Health Technology Assessment-National Institute for Health Research 2009: Vol 13: No 40 DOI:10.3310/hta13400. HMSO ISSN 1366-5278: www.hta.ac.uk/project/1611.asp Modeling the Cost Effectiveness of Interventions to Promote Breastfeeding, September 2007. National Collaboration Centre for Women’s and Child Health for NICE: www.nice.org.uk/nicemedia/live/11677/34695/34695.pdf Support for Breastfeeding Mothers (Review), The Cochrane Library 2009, Issue 4, http://onlinelibrary.wiley.com/o/cochrane/clsysrev/articles/CD001141/frame.html Public Health Guidance 11, Maternal and Child Nutrition http://www.nice.org.uk/nicemedia/pdf/ph011quickrefguide.pdf Appendix 4 - West Midlands Breastfeeding CQUINs (updated September 2010) A literature review (Appendix 5) was undertaken on preventing obesity in children aged <5. The review confirms that there is limited and immature evidence and a lack of comprehensive evidence on effective strategies to prevent obesity in younger children. There are some interesting individual studies that enhance and support recent NICE guidance around activity, familybased interventions and breast-feeding. The need remains for structured, focused and systematic research on child obesity prevention. Well-designed studies examining a range of interventions remain a priority. The findings in this review support the recommendations in the National Institute for Health and Clinical Excellence (NICE) guidelines on obesity. http://jpubhealth.oxfordjournals.org/content/29/4/368.full.pdf+html 5 D:\106746459.doc APPENDICES Appendix 1 Summary of Evidence for Breastfeeding Initiatives Adobe Acrobat Document Appendix 2 Financial benefits and improving health of low income households Adobe Acrobat Document Appendix 3 Obesity and Breastfeeding – A Review of the Evidence Adobe Acrobat Document Appendix 4 West Midlands Breastfeeding CQUINs Adobe Acrobat Document Appendix 5 Literature Review – Preventing Obesity in Children Aged <5 I:\Pbhealth\Health Strategy Unit (JB AO JD)\Julie Davis 2011\OBESITY - QIPP FINAL DOCS FROM ALEX - AMENDED\Infant Feeding - App KS.pdf REFERENCES 1 National Institute for Health and Clinical Excellence (NICE), Improving the nutrition of pregnant and breastfeeding mothers and children in low-income households, London: NICE, 2008. 2 Quigley MA et al, Breastfeeding and hospitalization for diarrheal and respiratory infection in the United Kingdom Millennium Cohort Study, Pediatrics, 2007; 119(4):e837–42. 3 Li et al. (2003); DH 2004a 4 Michels et al. (2007); DH 2004a 5 World Cancer Research Fund (2007); DH 2004a 6 http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsStatistics/DH_116060 (last accessed 15.2.11) 7 Horta BL, Bahl R, Martines JC et al. (2007) Evidence on the long term effects of breastfeeding: systematic reviews and meta-analyses. Geneva: World Health Organization 8 Op Cit (3) 9 Op Cit (4) 6 D:\106746459.doc 10 Op Cit (5) 11 http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_1065 01 (page 39). (Last accessed 15.2.11). 12 UNICEF. The Baby Friendly Initiative. 2009 [cited 2010 29/5/10]; Available from: www.babyfriendly.org.uk. 13 NICE. Improving the nutrition of pregnant and breast feeding mothers and children in low-income households. NICE; 2008 [cited 2010 29/5/10]; Available from: http://guidance.nice.org.uk/PH11/Guidance/pdf/English. 14 http://www.babyfriendly.org.uk/page.asp?page=61 15 Altobelli L, Baiocchi-Ureta N, Larson E. A controlled trial to extend the duration of exclusive breastfeeding among low income mothers in Lima, Peru. Unpublished. 1991. 16 http://www.babyfriendly.org.uk/page.asp?page=63 17 Renfrew M, Dyson L, Wallace L, D'Souza L, McCormick F, Spiby H. The effectiveness of public health interventions to promote the duration of breastfeeding. London: The National Institute for Health and Clinical Excellence; 2005. 18 Cattaneo A, Buzzetti R. Effect on rates of breast feeding of training for the baby friendly hospital initiative. BMJ. 2001 Dec 8;323(7325):1358-62. 19 http://www.babyfriendly.org.uk/page.asp?page=64 20 http://www.babyfriendly.org.uk/page.asp?page=66 21 http://www.babyfriendly.org.uk/page.asp?page=67 22 http://www.babyfriendly.org.uk/page.asp?page=68 23 Illingworth RS, Stone DG, Jowett GH, Scott JF. Self-demand feeding in a maternity unit. Lancet. 1952 Apr 5;1(6710):683-7. 24 Slaven S, Harvey D. Unlimited suckling time improves breast feeding. Lancet. 1981 Feb 14;1(8216):392-3. 25 http://www.babyfriendly.org.uk/page.asp?page=69 26 Barros FC, Victora CG, Semer TC, Tonioli Filho S, Tomasi E, Weiderpass E. Use of pacifiers is associated with decreased breast-feeding duration. Pediatrics. 1995 Apr;95(4):497-9. 27 Victora CG, Behague DP, Barros FC, Olinto MT, Weiderpass E. Pacifier use and short breastfeeding duration: cause, consequence, or coincidence? Pediatrics. 1997 Mar;99(3):445-53. 28 Righard L, Alade MO. Breastfeeding and the use of pacifiers. Birth. 1997 Jun;24(2):116-20. 29 Donnelly A, Snowden HM, Renfrew MJ, Woolridge MW. Commercial hospital discharge packs for breastfeeding women. Cochrane Database Syst Rev. 2000(2):CD002075. 30 Perez-Escamilla R, Pollitt E, Lonnerdal B, Dewey KG. Infant feeding policies in maternity wards and their effect on breast-feeding success: an analytical overview. Am J Public Health. 1994 Jan;84(1):89-97. 31 http://www.babyfriendly.org.uk/page.asp?page=70 Renfrew M, Dyson L, Wallace L, D'Souza L, McCormick F, Spiby H. The effectiveness of public health interventions to promote the duration of breastfeeding. London: The National Institute for Health and Clinical Excellence; 2005. 33 Kramer MS, Chalmers B, Hodnett ED, Sevkovskaya Z, Dzikovich I, Shapiro S, et al. Promotion of Breastfeeding Intervention Trial (PROBIT): a randomized trial in the Republic of Belarus. JAMA. 2001 Jan 2431;285(4):413-20. 34 Giovannini M, Banderali G, Radaelli G, Carmine V, Riva E, Agostoni C. Monitoring breastfeeding rates in Italy: national surveys 1995 and 1999. Acta Paediatr. 2003;92(3):357-63. 35 Cattaneo A, Buzzetti R. Effect on rates of breast feeding of training for the baby friendly hospital initiative. BMJ. 2001 Dec 8;323(7325):1358-62. 36 Lowry RJ, Billett A, Buchanan C, Whiston S. Increasing breastfeeding and reducing smoking in pregnancy: a social marketing success improving life chances for children. Perspectives in Public Health. 2009;129(6):277-80. 37 Op Cit (6) 38 Breastfeeding Promotion for Infants in Neonatal Units, A Systematic Review & Economic Analysis, Renfrew MJ, Craig D, Dyson L, McCornick F, Rice S, King SE, Misso E, Stenhouse E, Williams AF (2009) 32 7 D:\106746459.doc 39 Economic Evaluation of Enhanced Staff Contact for the Promotion of Breastfeeding for Low Birth Weight Infants, Rice SJ, Craig D, McCornick F, Renfrew MJ, Williams AF 8