RAD216 ADVANCED IMAGING MODALITIES & SPECIAL PROCEDURES APPLICATION OF DIGITAL FLUOROSCOPY: DIGITAL SUBTRACTION SUBTRACTION q which A technique removes bony anatomy which obscures contrastfilled vessels and organs. PHOTOGRAPHIC SUBTRACTION (FIRST ORDER) Involves the use of ANALOG techniques. The steps employed in obtaining subtraction images are numerous and require precision and skill. STEP 1 Obtain the scout film. It is i important t t tto position iti the th patient ti t the same way for each of the subsequent radiographs. Breathing instructions should be carefully explained so that they are replicated with each exposure. STEP 2 Place the scout film on the glass surface of the duplication machine. machine Place the special-purpose SUBTRACTION FILM on top of the scout film. Set the duplication machine to the correct exposure time and expose subtraction film. STEP 3 Process the exposed subtraction film. film The processed film becomes the DIAPOSITIVE MASK. This mask is the reversal of the scout film in that all of the densities are reversed. SUBTRACTION FILM SIMILAR CHARACTERISTICS TO DUPLICATION FILM SINGLE EMULSION HIGH CONTRAST SOLARIZED (DENSITY DECREASES WITH INCREASED EXPOSURE TO LIGHT) DISIMILAR CHARACTERISTICS REVERSAL OF DENSITIES DISTINCTIVE NOTCHING ON FILM CORNER STEP 4 The contrast-enhanced radiographs are obtained using positioning and respiratory control similar to what was used in obtaining the scout radiograph. STEP 5 The contrast-enhanced radiograph and the mask are positioned together on the glass of the duplicating machine so that all features are precisely superimposed. This is a very difficult step and requires patience and meticulous attention to detail. STEP 6 After carefully placing the mask and contrast radiograph on the duplicating machine, a fresh subtraction film is placed over these. STEP 7 After exposing the subtraction film, it is processed. processed The resulting subtraction radiograph is obtained. This method produces contrastfilled vessels and organs free of bony superimposition. Contrast is seen as dark whereas other structures are lighter. MOCK SUBTRACTION (WITHOUT CONTRAST) SCOUT MASK CONTRAST CONTRAST - MASK DISADVANTAGES OF PHOTOGRAPHIC SUBTRACTION TIME CONSUMING PRECISION AND SKILL REQUIRED PATIENT FACTORS WILL DIMINISH QUALITY OF SUBTRACTION RADIOGRAPHS (INVOLUNTARY MOTION, ETC.) DIGITAL SUBTRACTION A technique q employing p y g the use of a computer to remove bony superimposition from contrast-filled images. DIGITAL SUBTRACTION METHODS TEMPORAL SUBTRACTION MASK MODE TIME INTERVAL DIFFERENCE ENERGY SUBTRACTION HYBRID SUBTRACTION MASK MODE The first step involves converting (digitizing) a pre-contrast image. This digitized image will be used as the mask. MASK MODE Subsequent contrast-filled images are also digitized. The mask is then used to mathematically subtract the bony densities from the contrast images so only the contrast-filled structures remain. MASK M CONTRAST IMAGES 1 2 3 4 5 SUBTRACTION IMAGES 1-M 2-M 3-M 4-M 5-M REMEMBER... When an image is digitized (by means of an analog analog-to-digital to digital converter) all of the densities of the image are converted into series of 1’s and 0’s. It should not be too difficult to see how bone can be mathematically removed from soft tissue since this is done pixel by pixel. TIME INTERVAL DIFFERENCE This temporal subtraction technique utilizes several masks. masks The first several images are obtained and digitized. After a pre-determined time in which contrast is allowed to fill the blood vessels, the first images are subtracted from later images. TIME INTERVAL DIFFERECE 1 2 3 7-2 8-3 9-4 4 10-5 5 6-1 TIME INTERVAL DIFFERENCE This technique is especially useful when the contrast contrast-filled filled structures are susceptible to motion artifacts such as heart motion. These defects are called MISREGISTRATION ARTIFACTS. Misregistration results from the pixels from each image not lining up precisely. ENERGY SUBTRACTION This technique takes advantage of the attenuation differences between tissues and contrast media when different x-ray energies are used. ENERGY SUBTRACTION Especially important to this technique is the k-shell absorption edge of the iodine. By using two different x-ray energies on either side of the k-shell edge of iodine, photoelectric absorption of iodine is enhanced or diminished tremendously in comparison to surrounding tissues. ENERGY SUBTRACTION The difference in photoelectric absorption of iodine compared to the tissues is what makes this type of subtraction possible. ENERGY SUBTRACTION Two methods can be used to generate different energy spectra. spectra The first is to alter the kVp between 70 and 90 kVp. The other (preferred) is to introduce two dissimilar metal filters into the x-ray beam in alternating fashion (using a fly wheel). LIMITATIONS OF DIGITAL SUBTRACTION The main disadvantage of digital subtraction is the small field of view (FOV). Consequently, digital subtraction is limited to relatively small areas of the body.