Aetna Precertification Notification 503 Sunport Lane, Orlando, FL 32809 Phone: 1-866-503-0857 FAX: 1-888-267-3277 Multiple Sclerosis Medication Precertification Request Page 1 of 2 (All fields must be completed and legible for Precertification Review.) Please indicate: Start of treatment: Start date / / Continuation of therapy: Date of last treatment / For Medicare Advantage Part B: FAX: 1-844-268-7263 / Precertification Requested By: Phone: Fax: A. PATIENT INFORMATION First Name: Last Name: Address: City: Home Phone: State: Work Phone: DOB: Allergies: Current Weight: lbs or ZIP: Cell Phone: E-mail: kgs Height: inches or cms B. INSURANCE INFORMATION Aetna Member ID #: Group #: Insured: Medicare: Yes Does patient have other coverage? If yes, provide ID#: Insured: No If yes, provide ID #: Medicaid: Yes Yes No Carrier Name: No If yes, provide ID #: C. PRESCRIBER INFORMATION First Name: Last Name: Address: City: Phone: Fax: (Check One): State: St Lic #: Provider E-mail: NPI #: DEA #: Neurologist Primary Care D.O. N.P. P.A. ZIP: UPIN: Office Contact Name: Specialty (Check one): M.D. Phone: Other: D. DISPENSING PROVIDER/ADMINISTRATION INFORMATION Place of Administration: Self-administered Physician’s Office Outpatient Infusion Center Phone: Center Name: Home Infusion Center Phone: Agency Name: Administration code(s) (CPT): Dispensing Provider/Pharmacy: Patient Selected choice Physician’s Office Retail Pharmacy Specialty Pharmacy Mail Order Other: Name: Phone: Fax: TIN: PIN: E. PRODUCT INFORMATION Request is for: Dose: Aubagio Plegridy Avonex Rebif Frequency: Betaseron Tecfidera Copaxone Tysabri Extavia Gilenya Glatopa Lemtrada (Failure to indicate dose and frequency may extend review time) F. DIAGNOSIS INFORMATION – Please indicate primary ICD Code and specify any other where applicable. Primary ICD Code: Secondary ICD Code: Other ICD Code: G. CLINICAL INFORMATION – Required clinical information must be completed in its entirety for all precertification requests. For All Requests Yes No Does the patient have a documented diagnosis of relapsing remitting multiple sclerosis? Yes No Has the patient experienced signs and symptoms of Clinically Isolated Syndrome suggestive of MS that has been confirmed with magnetic resonance imaging (MRI)? Yes No Will the drug requested be used as monotherapy? Yes No Has the patient received samples of any of the MS products? If yes, please indicate which products: ______________________________________ (Sampling of any the Multiple Sclerosis products does not guarantee coverage under the provisions of the pharmacy benefit) For COPAXONE: Yes No Is the request for 20 mg of Copaxone? If yes, Yes No Does the patient have a contraindication, intolerance or allergy to Glatopa? Yes No Does the patient have a documented failure of an adequate trial of Glatopa? If yes, please indicate which of the following describe the evidence of treatment failure: Yes No The patient has increasing relapses (defined as two or more relapses in a year, or one severe relapse associated with either poor recovery or MRI lesion progression) Yes No The patient has lesion progression by MRI (increased number or volume of gadolinium-enhancing lesions, T2 hyperintense lesions or T1 hypointense lesions) Yes No The patient has worsening disability (sustained worsening of Expanded Disability Status Scale (EDSS) score or neurological examination findings) For GILENYA: Yes No Does the patient have a documented recent (within 6 months) complete blood count (CBC)? Yes No Does the patient have a documented recent (within 6 months) liver transaminase and bilirubin? Yes No Will the patient have an EKG prior to the first dose and at the end of the observation period? Continued on next page GR-68750 (12-15) Multiple Sclerosis Medication Precertification Request Page 2 of 2 (All fields must be completed and legible for Precertification Review.) Patient First Name Patient Last Name Patient Phone Aetna Precertification Notification 503 Sunport Lane, Orlando, FL 32809 Phone: 1-866-503-0857 FAX: 1-888-267-3277 For Medicare Advantage Part B: FAX: 1-844-268-7263 Patient DOB G. CLINICAL INFORMATION (continued) – Required clinical information must be completed in its entirety for all precertification requests. For GILENYA – also complete the following: Yes No Has the patient had a recent (within the last 6 months) occurrence of myocardial infarction, unstable angina, stroke, transient ischemic attack, decompensated heart failure requiring hospitalization, or Class III/IV heart failure? Yes No Does the patient have history or presence of Mobitz Type II 2nd degree or 3rd degree AV block or sick sinus syndrome? Yes No Does the patient have a pacemaker? Yes No Does the patient have a baseline QTc interval ≥500 ms (as measured on most recent EKG)? Yes No Is the patient on any Class Ia or Class III anti-arrhythmic drugs? Yes No Does the patient have a documented baseline ophthalmologic examination? Yes No Does the patient have a documented history of chicken pox or administration of the varicella zoster vaccine (VZV)? Yes No If female, does the patient have a documented negative pregnancy test? For AUBAGIO, AVONEX, BETASERON, EXTAVIA, LEMTRADA, PLEGRIDY, TECFIDERA, & TYSABRI – also complete the following: Yes No Has the patient received samples for the drug being requested? (Sampling of medication does not guarantee coverage under the provisions of the pharmacy benefit) Yes No Does the patient have a contraindication, intolerance or allergy to Copaxone or Glatopa? Yes No Does the patient have a documented failure of an adequate trial of Copaxone or Glatopa? If yes, please indicate which of the following describe the evidence of treatment failure: The patient has increasing relapses (defined as two or more relapses in a year, or one severe relapse associated with either poor recovery or MRI lesion progression) The patient has lesion progression by MRI (increased number or volume of gadolinium-enhancing lesions, T2 hyperintense lesions or T1 hypointense lesions) The patient has worsening disability (sustained worsening of Expanded Disability Status Scale (EDSS) score or neurological examination findings) Yes No Does the patient have a contraindication, intolerance or allergy to Gilenya? Yes No Does the patient have a documented failure of an adequate trial of Gilenya? If yes, please indicate which of the following describe the evidence of treatment failure: The patient has increasing relapses (defined as two or more relapses in a year, or one severe relapse associated with either poor recovery or MRI lesion progression) The patient has lesion progression by MRI (increased number or volume of gadolinium-enhancing lesions, T2 hyperintense lesions or T1 hypointense lesions) The patient has worsening disability (sustained worsening of Expanded Disability Status Scale (EDSS) score or neurological examination findings) Yes No Does the patient have a contraindication, intolerance or allergy to Rebif? Yes No Does the patient have a documented failure of an adequate trial of Rebif? If yes, please indicate which of the following describe the evidence of treatment failure: The patient has increasing relapses (defined as two or more relapses in a year, or one severe relapse associated with either poor recovery or MRI lesion progression) The patient has lesion progression by MRI (increased number or volume of gadolinium-enhancing lesions, T2 hyperintense lesions or T1 hypointense lesions) The patient has worsening disability (sustained worsening of Expanded Disability Status Scale (EDSS) score or neurological examination findings) For AUBAGIO – also complete the following: Yes No Does the patient have a documented (within 6 months) complete blood count (CBC)? Yes No Does the patient have a documented (within 6 months) liver transaminase and bilirubin? Yes No Does the patient have a documented (within 6 months) Tuberculin skin test to check latent Tuberculosis? Yes No Has/will the patient’s blood pressure be monitored at initiation and during treatment? Yes No If female, does the patient have a documented negative pregnancy test? Yes No If female, is there confirmation that reliable contraception will be used during treatment with Aubagio? For LEMTRADA – also complete the following: Yes No Is the patient HIV negative? For Tecfidera – also complete the following: Yes No Does the patient have a documented recent (within 6 months) complete blood count (CBC)? For TYSABRI – also complete the following: Yes No Does the patient have a documented anti-JCV antibody test with ELISA prior to initiating treatment? Yes No Has the patient had a documented anti-JCV antibody test with ELISA within the last 12 months? If yes, please indicate the date of testing: / / H. ACKNOWLEDGEMENT Request Completed By (Signature Required): Date: / / Any person who knowingly files a request for authorization of coverage of a medical procedure or service with the intent to injure, defraud or deceive any insurance company by providing materially false information or conceals material information for the purpose of misleading, commits a fraudulent insurance act, which is a crime and subjects such person to criminal and civil penalties. The plan may request additional information or clarification, if needed, to evaluate requests. GR-68750 (12-15)