Curriculum Vitae PERSONAL INFORMATION Name: Xing-Hai Liu, PhD Contact Information: College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou, 310014, P.R. China Email: xhliu@zjut.edu.cn RESEARCH INTERESTS Organic Synthesis of Bioactive Molecular Computer-Aided Drug Design Enzyme Preparation and Test the biological activity Molecular Modeling and Quantum Chemistry Computation EDUCATION AND WORK EXPERIENCE B.Sc, 2000.09-2004.06, Zhejiang Normal University, China; PhD, 2004.09-2009.06, Nankai University, China; Research Fellow, 2009.07-2010.01, Shanghai Chempartner Co. LTD Assistant Professor, 2010.01-2012, Zhejiang University of Technology Associate professor, 2012-Now, Zhejiang University of Technology JOURNAL REVIEWER Journal of Agricultural and Food Chemistry European Journal of Medicinal Chemistry Chemical Biology & Drug Design Bioorganic & Medicinal Chemistry Pest Management Science Chinese Journal of Organic Chemistry Letters in Organic Chemistry Monatshefte für Chemie - Chemical Monthly Chinese Journal of Structural Chemistry Letters in Drug Design & Discovery Molecules Research on Chemical Intermediates Journal of the Chemical Society of Pakistan Molecular Diversity Phosphorus, Sulfur and Silicon and the Related Elements LIST of PUBLICATIONS and PRESENTATION Papers [1] Guo-Xiang Sun, Zhao-Hui Sun, Ming-Yan Yang, Xing-Hai Liu*, Yi Ma and Yun-Yang Wei, Design, Synthesis, Biological Activities and 3D-QSAR of New N,N'-Diacylhydrazines Containing 2,4-Dichlorophenoxy Moieties, Molecules. 2013, 18(12), 14876-14891. [2] Na-Bo Sun, Jian-Qun Fu, Jian-Quan Weng, Jian-Zhong Jin, Cheng-Xia Tan and Xing-Hai Liu*, Microwave Assisted Synthesis, Antifungal Activity and DFT Theoretical Study of Some Novel 1,2,4-Triazole Derivatives Containing the 1,2,3-Thiadiazole Moiety, Molecules 2013, 18(10), 12725-12739. [3] Na-Bo Sun, Yan-Xia Shi, Xing-Hai Liu*, Yi Ma, Cheng-Xia Tan, Jian-Quan Weng, Jian-Zhong Jin and Bao-Ju Li, Design, Synthesis, Antifungal Activities and 3D-QSAR of New N,N'-Diacylhydrazines Containing 2,4-Dichlorophenoxy Moiety, International Journal of Molecular Sciences. 2013; 14(11):21741-21756. [4] Sun, Na-Bo; Liu, Xing-Hai*; Weng, Jian-Quan ; Tan, Cheng-Xia, An Unexpected Product N-(3-((2-fluorobenzyl)thio)-5-methyl-4H-1,2,4-triazol-4-yl)acetimidamide: Synthesis and Structure Analysis. Journal of the Chemical Society of Pakistan, 2013, 35, 499-502. [5] Su, Na-Na; Li, Yao; Yu, Shu-Jing; Zhang, Xiao; Liu, Xing-Hai*; Zhao, Wei-Guang, Microwave-assisted synthesis of some novel 1,2,3-triazoles by click chemistry, and their biological activity, Research on Chemical Intermediates, 2013, 39, 759-766. [6] Jin, Jian-Chang; Sun, Zhao-Hui ; Yang, Ming-Yan; Wu, Jing; Liu, Xing-Hai*, Synthesis, Crystal Structure, and Theoretical Studies of N-(4-((4-chlorobenzyl)oxy)phenyl)-4(trifluoromethyl)pyrimidin-2-amine, Journal of Chemistry, 2013,2013, 521757. [7] Tong Jian-Ying; Wu Hong-Ke; Sun Na-Bo; Liu, Xing-Hai*, Synthesis, Crystal Structure and Biological Activity of a New 1,2,4-Triazole Derivative, Chinese Journal of Structural Chemistry, 2013, 32, 607-611. [8] Cui, Can; Wang, Zhi-Peng; Du, Xiu-jiang; Wang, Li-Zhong; Yu, Shu-Jing; Liu, Xing-Hai*; Li, Zheng-Ming ; Zhao, Wei-Guang, Synthesis and Antiviral Activity of Hydrogenated Ferulic Acid Derivatives, Journal of Chemistry, 2013, 2013, 269434. [9] Liu, Xing-Hai; Weng, Jian-Quan; Tan, Cheng-Xia, Synthesis, Crystal Structure, and Fungicidal Activity of 5-(4-cyclopropyl-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)-4-methyl-1,2,3thiadiazole, Journal of Chemistry, 2013, 2013, 306361. [10] Tong Jianying; Shi Yanxia; Liu Xing-Hai*; Sun Nabo; Li Baoju, Synthesis and Fungicidal Activity of 1,2,4-Triazole Derivatives Containing 2-Fluorophenyl Moiety, Chinese Journal of Organic Chemistry, 2012, 32, 2373-2377. [11] Xue, Yong-Lai; Zhang, Yong-Gang; Liu, Xing-Hai*, Synthesis, Crystal Structure and Biological Activity of 1-Cyano-N-(2,4-dichlorophenyl)cyclopropanecarboxamide, Asian Journal of Chemistry, 2012, 24, 5087-5089. [12] Weng, Jian-Quan; Wang, Lei; Liu, Xing-Hai*, Synthesis, Crystal Structure and Herbicidal Activity of a 1, 2, 4-triazol-5(4H)-one Derivative, Journal of the Chemical Society of Pakistan, 2012, 34, 1248-1252. [13] Liu, Xing-Hai*, Zhao, Wei-Guang; Wang, Bao-Lei; Li, Zheng-Ming, Synthesis, bioactivity and DFT structure-activity relationship study of novel 1,2,3-thiadiazole derivatives, Research on Chemical Intermediates, 2012, 38, 1999-2008. [14] Wu, Rui; Zhu, Cong; Du, Xiu-Jiang; Xiong, Li-Xia; Yu, Shu-Jing ; Liu, Xing-Hai*, Li, Zheng-Ming; Zhao, Wei-Guang, Synthesis, crystal structure and larvicidal activity of novel diamide derivatives against Culex pipiens, Chemistry Central Journal, 2012, 6, 99. [15] Xue, Yong-Lai; Zhang, Yong-Gang; Liu, Xing-Hai*, Synthesis, Crystal Structure and Biological Activity of 1-Cyano-N-(4-bromophenyl)cyclopropanecarboxamide, Asian Journal of Chemistry, 2012, 24, 3016-3018. [16] Chen, Pei-Quan; Tan, Cheng-Xia; Weng, Jian-Quan; Liu, Xing-Hai*, Synthesis, Structure and DFT Calculation of Chlorimuron-ethyl, Asian Journal of Chemistry, 2012, 24, 2808-2810. [17] Liu, Xing-Hai*; Pan, Li; Weng, Jian-Quan; Tan, Cheng-Xia; Li, Yong-Hong; Wang, Bao-Lei ; Li, Zheng-Ming, Synthesis, structure, and biological activity of novel (oxdi/tri)azoles derivatives containing 1,2,3-thiadiazole or methyl moiety, Molecular Diversity, 2012, 16, 251-260. [18] Tan, Cheng-Xia ; Shi, Yan-Xia; Weng, Jian-Quan; Liu, Xing-Hai*; Li, Bao-Ju; Zhao, Wei-Guang, Synthesis and Antifungal Activity of 1,2,4-triazole Derivatives Containing Cyclopropane Moiety, Letters in Drug Design & Discovery, 2012, 9, 431-435. [19] Xue, Yong-Lai; Liu, Xing-Hai*; Zhang, Yong-Gang, Synthesis, Crystal Structure and Biological Activity of 1-Cyano-N-phenylcyclopropanecarboxamide, Asian Journal of Chemistry, 2012, 24, 1571-1574. [20] Weng, Jian-Quan; Tan, Cherig-Xia; Liu, Xing-Hai*, Synthesis and fungicidal activity of hydrazones containing 4-methylbenzo[d] thiazole moiety, Journal of Pesticide Science, 2012, 37, 164-168. [21] Tan, Cheng-Xia ; Weng, Jian-Quan ; Liu, Zheng-Xiao ; Liu, Xing-Hai*; Zhao, Wei-Guang, Synthesis, Crystal Structure, and Fungicidal Activity of a Novel 1,2,3-Thiadiazole Compound, Phosphorus, Sulfur and Silicon and the Related Elements, 2012, 187, 990-996. [22] Liu, Xing-Hai*; Pan, Li; Tan, Cheng-Xia; Weng, Jian-Quan; Wang, Bao-Lei; Li, Zheng-Ming, Synthesis, crystal structure, bioactivity and DFT calculation of new oxime ester derivatives containing cyclopropane moiety, Pesticide Biochemistry & Physiology, 2011, 101, 143-147. [23] Liu, Xing-Hai*; Pan, Li ; Ma, Yi; Weng, Jian-Quan; Tan, Cheng-Xia; Li, Yong-Hong; Shi, Yan-Xia; Li, Bao-Ju; Li, Zheng-Ming ; Zhang, Yong-Gang, Design, Synthesis, Biological Activities, and 3D-QSAR of New N,N '-Diacylhydrazines Containing 2-(2,4-dichlorophenoxy)propane Moiety, Chemical Biology & Drug Design, 2011, 78: 689-694. [24] Liu, Xing-Hai*; Weng, Jian-Quan; Tan, Cheng-Xia; Pan, Li; Wang, Bao-Lei; Li, Zheng-Ming, Synthesis, Biological Activities and DFT Calculation of alpha-Aminophosphonate Containing Cyclopropane Moiety, Asian Journal of Chemistry, 2011, 23, 4031-4036. [25] Liu, Xing-Hai*; Weng, Jian-Quan; Tan, Cheng-Xia, Microwave Synthesis and Biological Activity of Hydrazone Derivatives Containing 1,2,3-Thiadiazole, Asian Journal of Chemistry, 2011, 23, 4064-4066. [26] Xing-Hai Liu, Cheng-Xia Tan, Jian-Quan Weng, Phase Transfer Catalyzed One Pot Synthesis and Biological Activity of Some Novel N- Pyrimidinyl -N’- Nicotinyl Thiourea Derivatives, Phosphorus, Sulfur and Silicon and the Related Elements, 2011, 186, 552-557. [27] Xing-Hai Liu, Cheng-Xia Tan, Jian-Quan Weng, Synthesis, Dimeric Crystal Structure and Fungicidal Activity of 1-(4-methylphenyl)-2-(5-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)-4phenyl-4H-1,2,4-triazol-3-ylthio)ethanone, Phosphorus, Sulfur and Silicon and the Related Elements, 2011, 186, 558-564. [28] Xing-Hai Liu, Pei-Quan Chen, Bao-Lei Wang, et al. High Throughput Receptor Based Virtual Screening Under ZINC-Database, Synthesis and Biological Evaluation of Inhibitors of Ketol-Acid Reductoisomerase, Chemical Biology & Drug Design, 2010, 74(2): 228-232. [29] Xing-Hai Liu, Li Pan, Yan-Xia Shi, et al. Solvent-, Catalyst-Free Synthesis and Antifungal Activities of α-Aminophosphonate Containing Cyclopropane Moiety, Chemical Research in Chinese Universities, 2010, inpress. [30] Xing-Hai Liu, Yan-Xia Shi, Yi Ma, et al. Synthesis of Some N, N′-diacylhydrazine Derivatives with Radical Scavenging and Antifungal activity, Chemical Biology & Drug Design, 2009, 73(3):320-327. [31] Xing-Hai Liu, Yan-Xia Shi, Yi Ma, et al. Synthesis, Antifungal Activities and 3D-QSAR Study of N-(5-substituted-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide, European Journal of Medicinal Chemistry, 2009, 44(7):2782-2786. [32] Xing-Hai Liu, Chuan-Yu Zhang, Wan-Cheng Guo, et al. Synthesis and Bioactivity of N’-(5-substituted-1,3,4-thiadiazol-2-yl)-N-cyclopropyformyl thiourea as Ketol Acid Reducto-isomerase Inhibitor, Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, 24(2): 545-552. [33] Xing-Hai Liu, Pei-Quan Chen, Bao-Lei Wang, et al. High Throughput Screening under ZINC-Database and Synthesis a Dialkylphosphinic Acid as a potential KARI Inhibitor, Phosphorus, Sulfur and Silicon and the Related Elements, 2008, 183:775-778. [34] Xing-Hai Liu, Pei-Quan Chen, Bao-Lei Wang, et al. Synthesis, Bioactivity, Theoretical and Molecular Docking Study of 1-cyano-N-substituted-cyclopropane -carboxamide as ketol-acid reductoisomerase inhibitor, Bioorganic & Medicinal Chemistry Letters, 2007, 17:3784-3788. [35] Xing-Hai Liu, Pei-Quan Chen, Feng-Qi He, et al. Structure, bioactivity and theoretical study of 1-cyano-N-p-tolylcyclo-propanecarboxamide, Structural Chemistry, 2007, 5:563-568. [36] Xing-Hai Liu, Chuan-Yu Zhang, Wei-Li Dong, et al KARI and its Inhibitor (Review), Progress in Chemistry, 2008, 11:1788-1797. [37] Xing-Hai Liu, Bao-Lei Wang, Zheng-Ming Li, Progress in Chemical Synthesis and Modification of Glucosamine (Review), Chemistry, 2006, 7, 484-492. [38] Xing-Hai Liu, Zheng-Ming Li, Bao-Lei Wang, Progress in Pesticidal Bioactivities for Chitosan Oligosaccharide (Review), Chinese Journal of Pesticide Chemistry, 2006, 8:1-7. [39] Xing-Hai Liu, Zheng-Ming Li, Bao-Lei Wang, Progress in Preparation Methods for Chitosan Oligosaccharide(Review), Tianjin Chemical Industry, 2006, 20:1-6. [40] Wan-Cheng Guo, Xing-Hai Liu, Pei-Quan Chen, et al Synthesis and Crystal Structure of 2-Amino-4-chloro-5- (4-methylbenzyl)-6-methylpyrimidine, Chinese Journal of Structural Chemistry, 2007, 26:1005-1008 [41] Feng-Qi He, Xing-Hai Liu, Bao-Lei Wang, et al. Synthesis and Biological Activity of a New Kinds of Bi-heterocyclic Pyrrodiazole Derivatives Containing Pyrazole, Heteroatom Chemistry, 2008, 19:21-27. [42] Feng-Qi He, Xing-Hai Liu, Bao-Lei Wang, et al. Synthesis, Structure and Biological Activities of Some Novel N-(4,6-disubstituted-pyrimidin-2-yl)-N'- (trifluoromethyl-phenyl)-guanidine Derivatives, Chinese Journal of Chemistry, 2008, 26:1481-1485. [43] Wan-Cheng Guo, Xing-Hai Liu, Yong-Hong Li, et al. Synthesis and Herbicidal Activities of Novel Sulfonylureas Containing 1,3,4-Thiadiazoles, Chemical Research In Chinese University, 2008, 24:32-35. [44] Wei-Li Dong, Xing-Hai Liu, Jun-Ying Xu, et al, Design and synthesis of novel anthranilic diamides containing 5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidine, Journal of Chemical Research, 2008, 9:530-534. [45] Feng-Qi He, Xing-Hai Liu, Bao-Lei Wang, et al. Synthesis and biological activity of new 1-[4-(substituted)-piperazin-1-ylmethyl]-1H-benzotriazole, Journal of Chemical Research, 2006, 12:809-811. [46] Wan-Cheng Guo, Xing-Hai Liu, Pei-Quan Chen, et al. Synthesis and Crystal Structure of 2-Amino-4-chloro-5- (4-methylbenzyl)-6-methylpyrimidine, Chinese Journal of Structural Chemistry, 2007, 26:1005-1008. [47] Wei-Li Dong, Xing-Hai Liu, Yi Ma, et al. Quantitive-Strucutre Activity Relationship (QSAR) study of a New Heterocyclic Insecticides Using CoMFA and CoMSIA, Heterocyclic Communications, 2009, inpress. [48] Bao-Lei Wang, Xing-Hai Liu, Zheng-Ming Li, Synthesis and Characteristic of O,O-Dimethyl-N-(2,2,2-trichloro-1-arylaminoethyl)Phosphoramidothioates, Phosphorus, Sulfur and Silicon and the Related Elements, 2009, 184: 2281-2287. [49] Wei-Li Dong, Jun-Ying Xu, Xing-Hai Liu, et al Synthesis, Structure and Biological Activities of Some Novel Anthranilic Acid Esters containing N-pyridylpyrazole, Chinese Journal of Chemistry, inpress. [50] Pei-Quan Chen, Xing-Hai Liu, Hong-Wei Sun, et al, Molecular Simulation Studies of Interactions between Ketol-Acid Reductoisomerase and Its Inhibitors Acta Chimica Sinica, 2007, 65, 1693-1701. [51] Lei Wang, Yi Ma, Xing-Hai Liu, et al. Synthesis, Herbicidal Activities and CoMFA Study of Some Novel Triazolinone Derivatives, Chemical Biology & Drug Design, 2009, 73(6):674-681. [52] Wei-Li Dong, Jun-Ying Xu, Xing-Hai Liu, et al. Synthesis, Structure and Biological Activities of Some Novel Anthranilic Acid Esters containing N-pyridylpyrazole, Chinese Journal of Chemistry, 2009, 27(3):579-586. [53] Chuan-Yu Zhang, Bao-Lei Wang, Xing-Hai Liu, et al. Facile Synthesis and Herbicidal Activities of New Isoxazole Derivatives Via 1,3-Dipolar Cycloaddition Reaction, Heterocyclic Communications, 2008, 14(6):397-404. [54] Cun-Gui Cheng, Xing-Hai Liu, Application of DTA on quality of different varieties of fritillary, Chinese Traditional and Herbal Drugs, 2004, 210-212. [55] Cun-Gui Cheng, Xing-Hai Liu, Pei-Xi Zhu, Microwave assisted and Airtight Solvent Extraction of Harpagoside from Radix Scrophulariae, Journal of Nanjing University of Science and Technology, 2006, 30, 243-247. [56] Cun-Gui Cheng, Ze-Feng Cheng, Xing-Hai Liu, Microwave-Assisted and Pressurized Solvent Extraction of Shionone from Tatarian aster Root. Chinese Pharmaceutical Journal , 2006, 41, 502-505. [57] Wan-Cheng Guo, Hai-Zhong Tan, Xing-Hai Liu, et al, Synthesis and Biological Activity of New Trisubstituted Pyrimidine Phenylsulfonylurea Derivatives, Chemical Journal of Chinese Universities, 2008, 29:319-323. [58] Wan-Cheng Guo, Mei-Yi Wang, Xing-Hai Liu, et al Synthesis and Herbicidal Activities of Novel 4,5,6-Trisubstituted Pyrimidine Sulfonylureas, Chemical Journal of Chinese Universities, 2007, 28:1666-1670. [59] Yong-Jun Xiao, Jian-Guo Wang, Xing-Hai Liu, et al Molecular Design,Synthesis and Biological Activity Evaluation of Novel AHAS Inhibitors Based on Receptor Structure, Chemical Journal of Chinese Universities, 2007, 28:1280-1282. [60] Wei-Li Dong, Jun-Ying Xu, Xing-Hai Liu, et al, Synthesis, Crystal Structure and Biological Activity of Novel Anthranilic Diamides Containing 1,2,3-Thiadiazole, Chemical Journal of Chinese Universities, 2008, 29:1990- 1994. [61] Wei-Li Dong, Jun-Ying Xu, Xing-Hai Liu, et al, Synthesis and Biological Activities of New Neonicotinoids Containing 4-Thiazolidinone, Chemical Journal of Chinese Universities, 2008, 29:1359-1362. [62] Jian-Guo Wang, Yong-Jun Xiao, Yong-Hong Li, Xing-Hai Liu, et al, Design, synthesis and biological activity of substituted-N-[4-(substituted-phenylsulfamoyl) phenyl]benzamide as potential AHAS inhibitors, Chinese Chemical Letters, 2006, 17: 1555-1558. [63] Cun-Gui Cheng, Dan-Ting Li, Xing-Hai Liu, et al, Comparative study on trace elements in Flos chrysanthemi and Flos chrysanthemi Indica. Spectroscopy and Spectral Analysis 2006, 26: 156-158. Conference Papers [1]. Xing-Hai Liu*, Xiao-Yan Xu, Cheng-Xia Tan, Jian-Quan Weng, Jie Chen, Synthesis and Herbicidal Activity of 8-chloro-3-(4-propylphenyl)-[1,2,4]triazolo[4,3-a]pyridine, The 10th National Congress of Pesticide Chemistry, Jinan, 2013 [2]. Xing-Hai Liu*, Cheng-Xia Tan, Jian-Quan Weng, Yong-Gang Zhang, Synthesis, Structure and Biological Activity of [1,2,4]Triazolo[4,3-a]pyridines, The 9th National Congress of Pesticide Chemistry, Yangzhou, 2011 [3]. Xing-Hai Liu, Bao-Lei Wang, Zheng-Ming Li, et al. Synthesis and Herbicidal Activity of Novel Bi-Heterocyclic 1,2,4-Triazole Derivatives Containing 1,2,3-thidiazole and cyclopropane Moieties, the 12th IUPAC International Congress of Pesticide Chemistry, Melbourne, Austrilia, 2010. [4]. Xing-Hai Liu, Pei-Quan Chen, Wan-Cheng Guo, et al. Rational Design, Synthesis and SAR Study of Some Cyclopropane Derivatives as KARI Inhibitors, 3rd International Symposium on Pesticide and Environmental Safety & 7th International Workshop on Crop Protection Chemistry and harmonization,China Agriculture University Press,Beijing,2007.(ORAL PRESENTATION AND POSTER AWARD) [5]. Xing-Hai Liu, Pei-Quan Chen, Wan-Cheng Guo, et al High Throughput Screening under ZINC-Database and Synthesis a Dialkylphosphinic Acid as a potential KARI Inhibitor, Abstract of 17th International Conference on Phosphorus Chemistry, Xiamen,2007. [6]. Xing-Hai Liu, Chuan-Yu Zhang, Wan-Cheng Guo, et al. Synthesis, and Herbicidal Activity of Some Novel Diacylhydrazines Containing 2,4-dichlorophenoxy Moiety, The forth plant protection conference of Hunan and Hubei Province, Changsha,2007. (EXCELLENT PAPER) [7]. Xing-Hai Liu, Pei-Quan Chen, Wei-Li Dong, et al High Throughput Receptor Based Virtual Screening Under ZINC-Database, Synthesis and Biological Evaluation of Inhibitors of Ketol-Acid Reductoisomerase, The 13rd Annual of PCCIES of China, 2008, 293-296. [8]. Xing-Hai Liu, Wei-Li Dong, Guo-Rong He, et al Synthesis and DPPH Radical-Scavenging Activity of Some Novel N,N′-diacylhydrazines, The 26th Annual of Chinese Chemical Society, Tianjin, 2008 [9]. Xing-Hai Liu, Bao-Lei Wang, Wan-Cheng Guo, et al. Synthesis and Biological Activity of Novel 1-cyano-N-substituted-cyclopropanecarboxamide as KARI inhibitor, International Forum on Green Chemical Science & Engineering and Process System Engineering, Tianjin, 2006. [10]. Bao-Lei Wang, Xing-Hai Liu, Zheng-Ming Li, et al. Synthesis and Biological Activity of Some Novel 1,2,4-Triazole Mannich Bases Containing Trifluoromethyl and Piperazine Moieties, the 12th IUPAC International Congress of Pesticide Chemistry, Melbourne, Austrilia, 2010. [11]. Wei-Li Dong, Xing-Hai Liu, Jun-Ying Xu, et al, Design, Synthesis of Novel diamides (carboxylic acid esters) Containing N-phenyl pyrazole, The 26th Annual of Chinese Chemical Society, Tianjin, 2008. [12]. Bao-Lei Wang, Yu-Xin Li, Su-Hua Wang, Zheng-Ming Li, Xing-Hai Liu, et al. The Design, Synthesis and Biological Activity of Novel KARI Inhibitors, the 12th IUPAC International Congress of Pesticide Chemistry, Melbourne, Austrilia, 2010. [13]. Mei-Yi Wang, Xiao-Li Mu, Wan-Cheng Guo, Xing-Hai Liu, et al. Synthesis and Herbicidal Activity of Novel 5-Substituted Benzenesulfonylurea, International forum on green chemical science & engineering and process systems engineering, Tianjin, 2006 [14]. Wan-Cheng Guo, Mei-Yi Wang, Xing-Hai Liu, et al. The Synthesis and Biological Activity of Some Novel Pyrimidines, International forum on green chemical science & engineering and process systems engineering,Tianjin, 2006 [15]. Cun-Gui Cheng, Dan-Ting Li, Xing-Hai Liu, et al, Application of HATR-FTIR Spectroscopy to the Analysis of Nifedipine Tablets 20th Congress of the International Commission for Optics, 2006, 6024. [16]. Cun-Gui Cheng, Bei Wang, Xing-Hai Liu, et al, FTIR Study on the Normal and Malignant Gastric Tissues, 20th Congress of the International Commission for Optics, 2006, 6026. Patent [1]. Application of diacylhydrazine compounds as herbicide. Chinese Patent, CN101889577 [2]. Application of diacylhydrazine-type compounds as plant growth regulator. Chinese Patent, CN101889576 [3]. Application of acylhydrazone derivatives as fungicide. Chinese Patent, CN101874496 [4]. Application of diacyl hydrazides as fungicides. Chinese Patent, CN101874485 [5]. Preparation of N-pyridinecarbonyl N'-pyrimidyl thiourea derivatives as agrochemical bactericides. Chinese Patent, CN101851229 [6]. Preparation of benzothiazolinone derivatives as pesticides and/or antibacterial agents. Chinese Patent, CN101845027 [7]. New 1,2,4-triazole derivative useful for preparing herbicide for preventing and treating dicotyledon, preferably rape and/or monocot, preferably grass, Chinese Patent, CN 102775361 [8]. Use of triazolopyridine derivative for preparing drug for resisting agricultural fungi, e.g. Fusarium oxysporum, Chinese Patent, CN 102669121 [9]. New substituted 2-(3-(3-methoxyphenyl)-propionylamino)-3-methyl-N-(1-phenyl-ethyl)-butyramide derivatives useful as pesticides, insecticides for controlling e.g. mosquitoes, and as fungicides for treating e.g. early blight of tomato, Chinese Patent, CN 102627579 [10]. Usage method of triazole pyridine derivative useful for preparing medicine for treating infection caused by fungus e.g. Fusarium oxysporum, Chinese Patent, CN 102675309 [11]. Use of bihydrazide compound for regulating growth of plants and preventing rooting of cucumber cotyledon, Chinese Patent, CN 101889576 [12]. Use of dihydrazide compound as fungicide used for treating cucumber scab, cucumber powdery mildew, cucumber solani disease, cucumber leaf spot or cucumber anthracnose Chinese Patent, CN 101874485