Food Additives and Health 食物添加劑與健康 Prof. Susanna S. T. Lee Department of Biochemistry & Environmental Science Programme < lee2022@cuhk.edu.hk> Objectives: This lecture intends to introduce some common types of food additives and their specific functions and importance in the production and preservation of food products. The potential health risks of consuming these food additives, and the current legislations in the HKSAR governing the use of food additives will also be discussed. Summary: Food additives have been used for centuries to improve the quality (e.g., tastes, color, and shelf-life) of food products. Food additives are chemicals, other than the basic food component, intentionally added to food during production, processing, storage, and/or packaging to produce a desired effect. Today, more than 2000 different additives are being used in foods and there has always been some concern regarding the potential health risks of consuming these additives in foods. In the following table, the specific functions, potential health risks and the HKSAR legislations regarding the use of some common food additives are summarized. Food additives Flavor enhancers Examples Functions Monosodium glutamate 調味增添劑 穀氨酸單鈉 Modify the taste of Chinese natural and Restaurant synthetic flavor Syndrome Classified as GRAS ADI not specified Artificial sweeteners (MSG) 味精 Synthetic, noncarbohydrates: Saccharin Provide low calorie, sweetened foods for consumer groups with special dietary needs Food adulteration (artificial sweeteners) regulations 人造糖,代糖, 人工代糖, 增 甜劑, 甜味劑 薩克林, 糖精, Cyclamate 環磺酸鹽, Health concerns Metabolite of aspartame induces mental retardation in Phenylketonuria (PKU) patient 代謝性先天缺陷苯 Aspartame 丙酮尿的病人 阿斯巴甜, 阿斯伯特, 阿斯巴特 Aspartame has been linked to brain dysfunction 天冬胺酸代糖, Acesulfame-K 醋磺內酯甲 M5L2-1 Regulations 食物攙雜(人造糖) 規例 Coloring agents 色素 Food additives Nitrites (NO2-) 亞硝酸鹽 Natural (10%) Synthetic (90%): Tartrazine Impart desired color to food and restore lost color Allergic reaction in some people 過敏反應 酒石黃, 檸檬黃 Coloring matter in food regulations 食物內色素規例 Examples Functions Health concerns Regulations Sodium nitrite Formation of pink color in cured meat and inhibit the growth of Clostridium botulinum Methemoglobinemia Preservatives in food regulations 正鐵血紅蛋白症 食物內防腐劑規例 (肉毒梭菌, 亞硝胺 亞硝酸鈉 Carcinogenic nitrosamines 肉毒桿菌) Antioxidants 抗氧化劑 Natural: vitamin C and E Synthetic: BHA Retard autooxidation in fatcontaining foods May induce cancers and cause hemorrhage Preservatives in food regulations 食物內防腐劑規例 丁基羥基甲氧苯 BHT 二丁基羥基甲氧苯 References: 1. Concon, J. M. (1988). Food Toxicology: Part B. Contaminants and Additives. Marcel Dekker Inc., New York. 2. Maga, J. A. and Tu, A. T. (1995). Food Additive Toxicology. Marcel Dekker Inc., New York. 3. Millichap, J. G. (1993). Environmental Poisons in Our Food. ONB Publisher, Chicago. 4. Shibamoto, T. and Bjeldanes, L. F. (1993). Introduction to Food Toxicology. Academic Press, Inc. Harcourt Brace & Company, New York. 5. Taylor, S. L. and Scanlan, R. A. (1989). Food Toxicology: A Perspective on the Relative Risk. Marcel Dekker Inc., New York. 6. Colouring Matter in Food Regulations. Chapter 132 Subsidiary Legislation. Authorized Loose-leaf edition. Government Printer, Hong Kong. 7. Preservatives in Food Regulations. Chapter 132 Subsidiary Legislation. Authorized Loose-leaf edition. Government Printer, Hong Kong. 8. Food Adulteration (Artificial Sweeteners) Regulations. Chapter 132 Subsidiary Legislation. Authorized Loose-leaf edition. Government Printer, Hong Kong. 9. Walker, R. and Lupien, J. R. (2000). The Safety evaluation of monosodium glutamate. J. Nutr. 130: 1049S-1052S. 10. Choice Magazine 選擇 p. 31-34. Vol. 184. 1992. 11. Choice Magazine 選擇 p. 4-13. Vol. 208. 1994. 12. Choice Magazine 選擇 p. 11-18. Vol. 214. 1994. 13. Choice Magazine 選擇 p. 4-7. Vol. 217. 1994. M5L2-2 14. Choice Magazine 選擇 p. 14-22. Vol. 244. 1997. 15. Choice Magazine 選擇 p. 4-15 Vol. 270. 1999. M5L2-3