BETH ISRAEL DEACONESS MEDICAL CENTER DEPARTMENT OF PHARMACY MANUFACTURING BOOK ACETIC ACID SOLUTION 3% Page 1 of 2 Last update: February 13, 2001 NAME OF PREPARATION: ACETIC ACID SOLUTION 3% - 500 mL MATERIALS NEEDED: Glacial Acetic Acid 99.7% (located in acid cabinet in IV Room) Sterile Water for Irrigation Glass Graduated Cylinder 15 mL 500 mL bottle #1 PROTECTIVE EQUIPMENT: Vertical Flow Hood Face Mask Goggles or Protective Glasses Acid-Resistant Gloves (located in acid cabinet) Gown DIRECTIONS: 1. Pour 15 mL from the irrigation bottle and discard. 2. Carefully measure 15 mL Glacial Acetic Acid in the graduate. 3. Pour the Glacial Acetic Acid into the 485 mL of water remaining in the irrigation bottle. Recap and rotate bottle to mix well. 4. Affix label as shown below. STABILITY INFORMATION: Store at: Expiration: Room Temp 6 months from date of preparation LABEL REQUIREMENTS: ACETIC ACID SOLUTION 3% 500 mL control #:______________ exp date:__________ Prep by: ____________ FOR EXTERNAL USE ONLY Note: Control Number is actual date of preparation. * A 5% solution is sometimes ordered. For a 5% solution, remove 25 mL of water and add 25 mL of Glacial Acetic Acid following the above procedures. D:\533560313.doc BETH ISRAEL DEACONESS MEDICAL CENTER DEPARTMENT OF PHARMACY MANUFACTURING BOOK ACETIC ACID SOLUTION 3% Page 2 of 2 Last update: February 13, 2001 CLEAN-UP: 1. Large spills of glacial acetic acid must be cleaned using the ACID SPILL KIT located next to the acid cabinet in the IV Room. If the kit is not available, Sodium Bicarbonate powder must be spread on the acid to buffer it before cleaning. 2. Small spills may be buffered with Sodium Bicarbonate injection and the graduated cylinder must be buffered with 5-10 mL of Sodium Bicarbonate solution before rinsing with water to prevent a strong gas from forming. 3. A Material Safety Data Sheet (MSDS) can be found in the Employee Safety Manual located in all pharmacy areas. D:\533560313.doc